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  • Articles  (12,414)
  • Taylor & Francis  (6,350)
  • Nature Publishing Company  (6,064)
  • Process Engineering, Biotechnology, Nutrition Technology  (10,465)
  • Mathematics  (1,949)
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  • 1
    Electronic Resource
    Electronic Resource
    Industry may benefit from EPA Regulations (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 725-725 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The U.S. Environmental Protection Agency (EPA) has made a bold move in announcing that it intends to regulate the release of genetically modified organisms into the environment (see BIO/TECHNOLOGY, 1983, 1:638). Despite the cost (approximately $10,000 to file) and the delay (at least 90 ...
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    URL: http://dx.doi.org/10.1038/nbt1183-725a
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  • 2
    Electronic Resource
    Electronic Resource
    Support Loans for University Research (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 725-725 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] It is inherently unfair to competing companies, especially small companies, for an institution to withhold licenses for the most basic tools of any technology. In cases like the Cohen-Boyer process patent and the Axel-Wigler patent granted to Columbia University for cotransformation of eukaryotic ...
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    URL: http://dx.doi.org/10.1038/nbt1183-725b
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  • 3
    Electronic Resource
    Electronic Resource
    Cooperation with Bioengineers stressed at SIM (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 730-731 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SARASOTA, Florida—Many symposia at the Society for Industrial Microbiology meeting appeared aimed at the bioengineer rather than the industrial microbiologist. The need for cooperation and understanding between the two groups was a recurring theme of the meeting, which was held here in ...
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    URL: http://dx.doi.org/10.1038/nbt1183-730
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  • 4
    Electronic Resource
    Electronic Resource
    Scientists Working on Enzymes for Therapy (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 734-735 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—As techniques for enzyme production, engineering, purification, and delivery improve, the range of enzyme applications to therapy is increasing. Doctors apply enzymes externally to burns and wounds, infuse enzymes into the bloodstream to promote or inhibit clotting, ...
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    URL: http://dx.doi.org/10.1038/nbt1183-734
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  • 5
    Electronic Resource
    Electronic Resource
    U.S. Patent Office Plans Reorganization to Deal With Genetic Engineering (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 732-734 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—The U.S. Patent and Trademark Office (PTO) is considering changes in personnel, patent classification, and lines of authority to encompass the rapid growth and new technologies of genetic engineering, according to assistant commissioner for patents Rene Tegtmeyer. Several ...
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    URL: http://dx.doi.org/10.1038/nbt1183-732b
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  • 6
    Electronic Resource
    Electronic Resource
    Monoclonal Makers Upping Production, Vying for New Contracts (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 736-740 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Top left: A calf “on line” at Bio-Response. Top right: A Celltech scientist demonstrates the scale of its new 100 liter fermentors. Bottom: Human hybridoma cells growing within Damon Biotech's capsules. NEW YORK, New York—Damon Biotech and Bio-Response plan to open new facilities ...
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    URL: http://dx.doi.org/10.1038/nbt1183-736
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  • 7
    Electronic Resource
    Electronic Resource
    Prospects for Pollution Control with Microbes (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 743-755 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Seeking a way to keep warm, the hobo thought he had discovered fuel oil when he opened the valve of the railroad tank car parked on a siding. Unfortunately, the car held not fuel oil but 21,000 gallons of a 50 percent formaldehyde solution. It gushed out of the tank, spilled over a stone railbed ...
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    URL: http://dx.doi.org/10.1038/nbt1183-743
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  • 8
    Electronic Resource
    Electronic Resource
    Brazil's Staggering Progress in Biofuels (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 676-676 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] One would hardly expect to find our planet's most grandiose biotechnology project in a nation whose inflation rate is 120 percent, whose massive debts threaten the fabric of international banking, and whose social discontent is such as to suggest violent upheavals, if not worse, in the near future. ...
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    URL: http://dx.doi.org/10.1038/nbt1083-676
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  • 9
    Electronic Resource
    Electronic Resource
    Patent Cooperation Treaty May Not Benefit Biotechnology (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 709-709 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Patent Cooperation Treaty, or PCT, gives inventors the option of reserving patent protection in 32 additional countries at the same time that they file in the U.S. Thirty-three countries ratified the 1978 treaty, under which a patent filed in one country forms the basis for protection in all ...
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    URL: http://dx.doi.org/10.1038/nbt1083-709
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  • 10
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    Biochemical Handbook (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 701-702 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biochemical Engineering and Biotechnology Handbook. Edited by Bernard Aikens and Ferda Mavituna. Pp. 1119. ISBN 0 333 332741 (The Nature Press: New York). $97.00 The authors have assembled an impressive array of information, undoubtedly useful to workers in the field. The book is divided ...
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    URL: http://dx.doi.org/10.1038/nbt1083-701b
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  • 11
    Electronic Resource
    Electronic Resource
    Human MCA Against Colon Cancer Produced At Litton (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 537-538 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] KENSINGTON, Maryland—A technique for producing human monoclonal antibodies directed against tumor antigens associated with human colorectal cancers has been developed at Litton Bionetics, which says it has produced more than 20 of these cancer-reactive monoclonals since the beginning of the ...
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    URL: http://dx.doi.org/10.1038/nbt0983-537
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  • 12
    Electronic Resource
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    How to Engineer Bacilli for Protein Secretion (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 543-543 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] STANFORD, California—Bacilli have a great track record in industry. More than a score of their secreted proteins (mostly cleaving enzymes) are successfully produced and widely employed by dozens of industries. But what about the future now that biotechnology has become something more than ...
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    URL: http://dx.doi.org/10.1038/nbt0983-543
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  • 13
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    Electronic Resource
    The Role of Computers in Biotechnology (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 565-575 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The revolutionary advances of the early 1970's, such as rapid nucleic acid sequencing, restriction enzyme technology, and recombinant DNA techniques, have produced an information explosion in the field of molecular biology. Millions of base pairs of DNA sequences are now known and must be analyzed; ...
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    URL: http://dx.doi.org/10.1038/nbt0983-565
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  • 14
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    Book Received (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 612-612 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biotechnology Made Simple. PJB Publications ed. Pp. 1127. (PJB Publications: 1983) $150; £75,00 This large-format paperback is a dictionary of terms used in biology and biochemistry. Figures from basic texts are included. A chronology of the emerging biotechnology industry may be ...
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    URL: http://dx.doi.org/10.1038/nbt0983-612
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  • 15
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    Molecular Biology Instrumentation (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 615-616 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] This month the New Products section will feature products with applications in several areas of biotechnology. The section will review reagents and equipment for molecular biology, genetic engineering, and microbiological experimentation; the companies marketing these products will be exhibiting ...
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    URL: http://dx.doi.org/10.1038/nbt0983-615
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  • 16
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    Microbial Strains, Cell Lines, and Vectors (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 613-614 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The American Type Culture Collection (ATCC), a non-profit organization located in Rockville, Maryland, recently made the following materials available for distribution to biotechnologists in industry and academia. These materials may be ordered from the Collection by using the ATCC® number. ...
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    URL: http://dx.doi.org/10.1038/nbt0983-613
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  • 17
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    Electronic Resource
    The Biology of the Interferon System (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 480-483 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Netherlands Organization for Applied Scientific Research (TNO) sponsored its second conference on “The Biology of the Interferon System” on 18–22 April 1983 in Rotterdam. Although it came only six months after the Third International Congress for Interferon Research, the ...
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    URL: http://dx.doi.org/10.1038/nbt0883-480
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  • 18
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    The Climate for Biotechnology: National Strategies Contrasted (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 490-492 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Nothing said more about the subject of the first stream of sessions at Biotech 83, entitled The Climate for Biotechnology, than the simple fact that approximately 1000 delegates were prepared to pay as much as £400 a head to register for the meeting. Although a surprising number of speakers ...
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    URL: http://dx.doi.org/10.1038/nbt0883-490
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  • 19
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    International Patents (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 507-508 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TITLE: Dispersant and Biodegradant Formulations for Treating Hydrocarbon-Polluted Waters INVENTORS: Claude Gatellier, Boulogne, Andree Plessis, Le Vesinet, Patrick Gateau, Trappes, and Jean-Pierre Durand, Chatou, FR ASSIGNEE: Institut Francais du Petrole, Fueil-Malmaison, FR FILING & ...
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    URL: http://dx.doi.org/10.1038/nbt0883-507
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  • 20
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    Reports from Biotech '83 (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 388-389 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BACTERIAL PLASTIC COMES TO MARKET LONDON, England—Despite its mixed experience with single-cell protein, Britain's ICI is determined to stay in the biotechnology business, and believes it may have found a new path to success. At the Biotech '83 conference and exhibition here ICI took one of ...
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    URL: http://dx.doi.org/10.1038/nbt0783-388
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  • 21
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    Bio Rad Bails Out IPRI (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 395-396 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN CARLOS, California—The financially plagued International Plant Research Institute (IPRI) has avoided bankruptcy, at least for now. Bio Rad, a Richmond, CA, manufacturer of clinical diagnostics, research products and instrumentation, stepped in at the end of May and purchased IPRI ...
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    URL: http://dx.doi.org/10.1038/nbt0783-395
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  • 22
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    First Keystone Conference on Plant Molecular Biology (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 410-412 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Most appropriately, the first Keystone Conference on Plant Molecular Biology began with a keynote address by Josef Schell (Rijksuniversiteit, Gent and Max Planck Institut fur Zuchtungsforschung, Koln) on the “Prospects for Genetic Engineering in Higher Plants.” Dr. Schell reviewed the ...
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    URL: http://dx.doi.org/10.1038/nbt0783-410
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  • 23
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    Laboratory Equipment (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 439-440 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Since the major component of any large batch of media is water, its quality must be carefully monitored. Pyrogen content of the water is also a very important consideration. A variety of filtration systems, deionizers, distilled-deionizing systems, mixed-bed ion exchangers, and similar products are ...
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    URL: http://dx.doi.org/10.1038/nbt0783-439
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  • 24
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    Biotechnology Directory (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 448-448 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biotechnology International Edited by Carmel Barnard. Three volumes. Vol. 1, 200 Pp., $400.00; Vol. 2, 252 Pp., $400.00; Vol. 3, 114 Pp., $400.00. $1000.00 for all three volumes. (IMS World Publications, Ltd., York House, 37 Queens Square, London WC1 N3BL, U.K.) 1982 ...
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    URL: http://dx.doi.org/10.1038/nbt0783-448a
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  • 25
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    Plant Breeding: Poised for Revolution (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 309-310 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] COLOGNE, W. Germany—The branch of industry now most sensitively poised for a revolution triggered by recombinant DNA technology is plant breeding, judging from several papers given at the recent conference held by COGENE (the International Council of Scientific Unions' Committee on Genetic Ex ...
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    URL: http://dx.doi.org/10.1038/nbt0683-309
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  • 26
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    Space Biotech Takes Off (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 310-313 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] HUNTSVILLE, Alabama—A bioprocessing factory in space may not be too far in the future. One of the projects on the March space shuttle mission, the first flight of the Challenger, was a successful experiment in which National Aeronautics and Space Administration (NASA) astronauts operated ...
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    URL: http://dx.doi.org/10.1038/nbt0683-310
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  • 27
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    Keystone Crops (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 314-314 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] KEYSTONE, CO—Agrigenetics scientists announced expression of transferred foreign plant genes in plant cells at a meeting here late in April. At the same meeting, Monsanto scientists reported genetically engineering entire plants by transfer ring bacterial genes to plant cells, then ...
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    URL: http://dx.doi.org/10.1038/nbt0683-314c
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  • 28
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    Economic Motives for Managing the Composting Microbial Ecosystem (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 341-342 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] An old biotechnology, composting, has recently come into widespread use as a sewage sludge treatment process. (See Review Article, p. 347.) North American cities composting at least a sizeable portion of their sludge (or soon to do so) include Washing ton, DC; Philadelphia, PA; Camden, NJ; ...
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  • 29
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    Biotechnology Improves Food Production, Processing (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 344-345 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although the food industry never fails to make the list of areas where the “biotechnology boom” will have a significant impact, few specific applications have as yet materialized. Several papers presented at the recent ASM seminar entitled “Biotechnology in the Food ...
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  • 30
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    McClintock's Remarkable Transposable Elements—thirty Years Later (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 346-346 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Acabal of biotechnologists and molecular biologists, gathered to mull over the future implications of their pioneering work, is hardly likely to become equally excited about studies carried out three decades ago by someone now in their eighties. But that is what happened recently at COGENE's latest ...
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  • 31
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    Health and Environmental Hazards in Biotechnology (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 359-361 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Applied Genetic Engineering Future Trends and Problems. By Morris A. Levin, George M. Kidd, Robert H. Zaugg, and Jeffrey R. Swarz, pp. 191. ISBN 0-8155-0925-1 (Noyes Publications) $24.00 This book deals broadly with applied biology, including genetic engineering. The future trends promised ...
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  • 32
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    Patent Analysis (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 373-375 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TITLE: Microbiological Production of Lower Aliphatic Carboxylic Acids INVENTORS: Marvin P. Bryant, and Barbara R. S. Genthner, both of Urbana, IL, US ASSIGNEE: University Patents, Inc., Norwalk, CT, US FILING & ISSUING DATA: U.S. Patent No.: 4,377,638 Date Issued: March 22, 1983 Lower ...
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  • 33
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    Patterns of Investment in Biotechnology (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 248-250 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Fundamental scientific inquiry in physics and mathematics over the past 50 years resulted in advances in man's ability to compute, to communicate, and to use energy in revolutionary ways. It is clear that each of these technologies has developed according to externally defined needs and objectives. ...
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  • 34
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    New Publications in Biotechnology (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 276-277 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Within the past decade the amount of newly published information relating to biotechnology has rapidly expanded. The growth in the number of biotechnology-related companies is far exceeded by the number of new books, journals, news sheets, and so on in the field. Many long-established publishing ...
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    Biotech '83 (1983)
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    Nature biotechnology 1 (1983), S. 277-277 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biotech '83, the first world conference and exhibition on the commercial applications and implications of biotechnology is taking place this month in London. Accompanying the conference will be the first international biotechnology exhibition. Displays from many of the world's leading biotech ...
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    Grants (1983)
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    Nature biotechnology 1 (1983), S. 369-371 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The following biotechnology-related grants were selected from a group of new awards recently announced by the Nation al Institutes of Health. The descriptions are excerpted from the technical abstracts accompanying the proposals. TITLE: Transposable genetic elements of maize INVESTIGATOR: ...
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    Merrill Lynch Launches Sci/Tech Mutual Fund (1983)
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    Nature biotechnology 1 (1983), S. 220-220 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, NY—Sci/Tech Holdings, the new international mutual fund specializing in technology stocks, completed its subscription period March 24 and began investing funds in April. Specializing in promising science and technology investments, including biotechnology, Sci/Tech hopes to ...
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    FMC, Centocor to Begin Joint Immunoresearch (1983)
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    Nature biotechnology 1 (1983), S. 225-226 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] MALVERN, PA—Immunorex, the FMC Corp.-Centocor joint venture formed to produce pharmaceuticals using human monoclonal antibodies, is also planning to do immunoregulation research leading to the development of in vitro diagnostics. Although Immunorex is yet to market a product, FMC has agreed ...
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    Microbial Mining and Metal Recovery: Corporations Take the Long and Cautious Path (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 228-235 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Leaching solution is sprayed by a sprinkler system on top of a copper-leaching dump. The recycled waste water, from which the copper sulfate has been removed, retains much ferrous iron and some sulfuric acid. Inset; Sulfolobus brierleyi. Scanning electron micrograph of the organism developing ...
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    Mini–Ti: A Truncated Plasmid Simplifies Gene Transfer (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 239-239 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] One of the most rapidly progressing areas of biotechnology is plant molecular biology. Several re cent reports in BIO/TECHNOLOGY have focused on the manipulation of the Ti plasmid, a large plasmid found in Agrobacteria. Laboratories in the United States and Europe have announced successful ...
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    Construction and Characterization of a Versatile Broad Host Range DNA Cloning System for Gram–Negative Bacteria (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 269-275 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A set of broad host range cloning vectors has been constructed from the IncW plasmid pSa. These vectors have been constructed from the transfer defective deletion derivative pSa151, which encodes resistance to kanamycin and spectinomycin–streptomycin. Two of the vectors also contain the ...
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    The Economics of Conservation (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 280-280 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A Wealth of Wild Species: Storehouse for Human Welfare. Norman Meyers. Pp. 274. ISBN 0-86531-132-3 (Western Press, Inc.: 1983). $27.00 This book is not specifically written for a business audience, but it is useful to those in the biotechnology industries. It offers a list of raw materials ...
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    Plasmids and Plasmid-Containing Organisms (1983)
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    Nature biotechnology 1 (1983), S. 291-294 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TITLE: Escherichia coli Bacteria Carrying Recombinant Plasmids and Their Use in the Fermentative Production of L-Tryptophan INVENTORS: David M. Anderson, Rockville, MD, Klaus M. Herrmann, and Ronald L. Somerville, West Lafayette, IN, US ASSIGNEE: Ajinomoto, Co., Inc., Tokyo, JP FILING & ...
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    Scientists Engineer Proteins for Cellular Export (1983)
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    Nature biotechnology 1 (1983), S. 146-147 
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    Notes: [Auszug] COLD SPRING HARBOR, New York—Several virus proteins that are normally anchored in a membrane have been genetically engineered to proteins that are exported from infected eukaryotic cells. The secreted proteins, which are biologically active, can be purified far more easily and quickly than ...
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    Advances in Gene Technology for Plants and Animals (1983)
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    Nature biotechnology 1 (1983), S. 169-171 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Plant molecular genetics has finally come of age: the Miami Winter Symposium on the application of gene technology to agriculture drew more than 700 participants. While naturally occurring genetic variability among sexually compatible plants has long been exploited by plant breeders, it is now ...
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    Experimental Methods for On–Line Mass Spectrometry in Fermentation Technology * (1983)
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    Nature biotechnology 1 (1983), S. 181-188 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] It is shown here how mass spectrometry (MS) can be used for on–line data acquisition in fermentation. MS was applied in this work to analyze gas and liquid phases. Gas phase analysis allows fast and accurate measurement of all gases of interest (O2, N2, CO2, Ar, He etc.). Liquid phase ...
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    Announcements (1983)
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    Nature biotechnology 1 (1983), S. 195-196 
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    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] APRIL MEETINGS April 10–15. Cellular Responses to DNA Damage (1983 UCLA Symposium on Molecular and Cellular Biology). Keystone, CO. Info: UCLA Symposia, Molecular Biology Institute, University of California, Los Angeles, CA 90024 April 11. Meeting of the Recombi-nant DNA Advisory Committee. ...
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    Patent Analysis (1983)
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    Nature biotechnology 1 (1983), S. 205-205 
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    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TITLE: Extrachromosomal Regulation of Expression INVENTORS: John J. Sninsky, Mountain View, CA, and Stanley N. Cohen, Portolla Valley, CA ASSIGNEE: The Board of Trustees of the Leland Stan ford Jr. University, Stanford, CA FILING AND ISSUING DATA: U.S. Patent No.: 4,374,927 Date Issued: ...
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    Closing Volume 1 of Bio/Technology with a Word of Thanks (1983)
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    Nature biotechnology 1 (1983), S. 821-821 
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    Notes: [Auszug] BIO/TECHNOLOGY is very pleased to close its first volume with this December issue. A healthy circulation base and steadily increasing interest from advertisers testifies to the demand for this unique international publication. Independent surveys and conversations with our readers show that ...
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    The BIO/TECHNOLOGY Stock Index of Specialty Firms (1983)
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    Nature biotechnology 1 (1983), S. 824-824 
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    Notes: [Auszug] BIO/TECHNOLOGY STOCK INDEX OF SPECIALTY FIRMS Price Oct. 15 Price Nov. 15 Percent Change 52 Week Hi-Low Market Capitalization in $ millions (stock price × number of shares outstanding) Companies Emphasizing Recombinant DNA Technology Amgen 71/2 63/4 −10 ...
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    Fermentation and Genetic Engineering: Problems and Prospects (1983)
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    Nature biotechnology 1 (1983), S. 847-856 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Discussions of the implementation of genetic engineering in industrial processes by means of fermentation in industrial reactors inevitably turn to problems of scale up. This term refers to the translation of small scale laboratory experiments into processes that can be used in an economically ...
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    Upjohn Consolidates Biotech Efforts into a Single Unit; Plans Expansion (1983)
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    Nature biotechnology 1 (1983), S. 837-837 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] KALAMAZOO, Michigan—The Upjohn Company, the multinational pharmaceutical concern headquartered here, has formed a biotechnology unit. Since the firm was granted more than 20 biotechnology-related patents last year—easily more than Genentech, Genex, and Cetus combined—the move is a ...
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    Gene Cloning in Bacilli Related to Enhanced Penicillin Acylase Production (1983)
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    Nature biotechnology 1 (1983), S. 879-882 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have isolated bacillus strains highly productive for penicillin acylase using conventional mutagenesis and screening techniques. This report describes the isolation of a 2.7 kb chromosomal DNA fragment from Bacillus megaterium which, when inserted in a multi–copy vector and transferred ...
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    Dutch Soften DNA Guidelines (1983)
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    Nature biotechnology 1 (1983), S. 18-20 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] THE HAGUE—The Ad Hoc Committee on Recombinant DNA Work in the Netherlands has proposed new guidelines for the use of genetically engineered microorganisms in cultures of 10 liters or more. Concluding that detailed regulations are neither necessary nor possible, the committee proposed that the ...
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    Analysis: Rubisco Gene Cloned (1983)
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    Nature biotechnology 1 (1983), S. 33-33 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The nuclear genomes of plants are typical of eukaryotes generally: large, complex, containing a variety of repeating sequences, probably transposons, and other elements. Genes, or at least cDNAs, for most of the major storage proteins, have been isolated, cloned, and mapped. These genes typically ...
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    Analysis: Dealkylases for Enzymatic Control of Pests (1983)
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    Nature biotechnology 1 (1983), S. 43-44 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Worldwide agriculture production has increased greatly since World War II, due in part to post-war discoveries and the subsequent large-scale use of synthetic fertilizers and pesticides. Many organochlorine insecticides, including DDT, dieldrin, and heptachlor, which initially provided good ...
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    Invitation to Readers (1983)
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    Nature biotechnology 1 (1983), S. 7-7 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The publication of this ambitious magazine/journal of industrial biology is similar in some respects to successful research and development projects in biotechnology. The seemingly endless planning, negotiating, hiring, and arduous work prior to the birth of BIO/TECHNOLOGY were conducted in ...
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    International Society for Plant Molecular Biology (1983)
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    Nature biotechnology 1 (1983), S. 38-43 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] On January 14–15, 1983, the International Society for Plant Molecular Biology (formerly the Plant Molecular Biology Association) held its first conference in Miami, Florida. The Conference focused on the higher plant and plant virus genomes. Because genomic variation is the source of improved ...
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    Microbial Enhancement of Oil Recovery (1983)
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    Nature biotechnology 1 (1983), S. 47-54 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Successful application of microorganisms in oil recovery will greatly increase well output. Most promising is the use of microbial products in the production of biosurfactants. Current efforts to develop research are hindered by the lode of in-depth databases. Microbial processes and products have ...
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    Monitoring Environmental Pollution in Marine Fishes by Immunological Techniques: The Immune Response of Fishes Exposed by Injection or Bath to Bacterial Isolates from Sludge and In Situ Exposure to Sludge (1983)
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    Nature biotechnology 1 (1983), S. 66-68 
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    Notes: [Auszug] Antibody to human enteric bacterial isolates from sewage sludge dumped into the ocean has been demonstrated in several species of marine teleost. Antibody profiles of these bacteria gathered on commercial species can show what contact fish have had with potentially pathogenic microorganisms which ...
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    Development and Application of Bacillus Thuringiensis Var. Israelensis Serotype H 14 as an Effective Biological Control Agent Against Mosquitoes in Israel * (1983)
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    Nature biotechnology 1 (1983), S. 74-76 
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    Notes: [Auszug] The use of a new strain of Bacillus thuringiensis has been successfully used in mosquito control in Israel. Toxicity tests with Culex pipiens and Aedes aegypti showed that the strain was effective in LD50 bioassays. Field trials with B. thuringiensis showed that several applications were needed and ...
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    Protecting Biotechnology (1983)
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    Nature biotechnology 1 (1983), S. 79-80 
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    Notes: [Auszug] Legal Protection For Microbiological And Genetic Engineering Inventions. By Roman Saliwanchik. Pp. 256. ISBN 0-201-10938-7. (Addison-Wesley: 1982.) $34.95. Technological breakthroughs in the biosciences during the past decade have created wide-ranging commercial possibilities. Among these ...
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    American Biotechnology Needs a Strategic Planning Center (1983)
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    Nature biotechnology 1 (1983), S. 7-7 
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    Notes: [Auszug] The United States has yet to form a consistent set of policies which addresses both the problems and the economic potential of biotechnology. Despite the fact that federal money continues to support excellent research, and that corporations have begun manufacturing the first generation of ...
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    A second Human Genome Project? (1998)
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    Nature biotechnology 16 (1998), S. 793-793 
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    Notes: [Auszug] With only 4% of the Human Genome Project completed, albeit ahead of schedule, one might conclude that the so–called genomics revolution has quite a bit more time on the meter. But there is another aspect of the human genome that we can no longer afford to ignore: The more than three million ...
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    Latin America: CYTED-BT: An international biotechnology network that works (1998)
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    Nature biotechnology 16 (1998), S. 794-794 
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    Notes: [Auszug] Too often, international programs for cooperation in biotechnology, particularly those involving “developing” countries, begin with the best intentions, but over time, sadly, produce very little in the form of tangible accomplishment. Thus, it is both refreshing and encouraging to find ...
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    No prokaryotic GPI anchoring (1998)
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    Nature biotechnology 16 (1998), S. 799-799 
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    Notes: [Auszug] To the editor: In a recent article1 in Nature Biotechnology, Jung et al. describe the construction of a chimerical protein made of Zymomonas mobilis levansucrase and Pseudomonas syringae ice nucleation protein (Inp). The fusion protein is expressed in Escherichia coli and displays cell surface ...
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    No prokaryotic GPI anchoring (reply) (1998)
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    Nature biotechnology 16 (1998), S. 799-799 
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    Notes: [Auszug] Jung et al. reply: Kozloff et al. identified phosphatidylinositol, which is a relatively rare component of the prokaryotic cell wall, as a major component of the ice-nucleating site on the outer surface off! syringae1. They also suggested that the Inp is structurally very similar to the GPI anchor ...
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    Centaur abandons US for European IPO (1998)
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    Nature biotechnology 16 (1998), S. 807-807 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Centaur Pharmaceuticals (Sunnyvale, CA) is the first US biotechnology company to go public abroad; it began listing on the Swiss exchange SWX (Zurich, Switzerland) on August 27, hoping to raise at least CFR80 million ($54 million). The opportunity for biotechnology initial public offerings ...
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    Mystery plea for review of seed and biotech mergers (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 811-811 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Somebody with deep pockets and a will to remain anonymous appears keen to redirect the course of the US agricultural biotechnology business sector. Arguing that recent and future consolidations could undermine innovation in this sector and eventually weaken US agricultural competitiveness, a ...
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    A genome-based approach for the identification of essential bacterial genes (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 851-856 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have used comparative genomics to identify 26 Escherichia coli open reading frames that are both of unknown function (hypothetical open reading frames or y-genes) and conserved in the compact genome of Mycoplasma genitalium. Not surprisingly, these genes are broadly conserved in the bacterial ...
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    A rational design strategy for protein hormone superagonists (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 871-875 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] By combining evolutionary considerations, sequence comparisons and homology modeling we have designed recombinant human thyroid-stimulating hormone (hTSH) analogs with increased receptor binding and activity. The introduction of seven basic residues into the peripheral loops of hTSH resulted in up ...
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    People (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 880-880 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Guilford Pharmaceuticals (Baltimore, MD) has announced the appointment of David H. Bergstrom as vice president, pharmaceutical and chemical development. Dr. Bergstrom joins Guilford from Hoechst Marion Roussel, where for the past two years he was director of pharmaceutical and analytical sciences. ...
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    Jeremy Rifkin is biotechnology's biggest fan (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 695-695 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Extreme fans are fanatics. And if we ventured the opinion that Jeremy Rifkin was fanatical when it came to biotech, few would disagree. But Rifkin's fanaticism is not, at least yet, of the variety that borders on lunacy. Quite the contrary, his deep passion for biotechnology is reflected by ...
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    Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 857-861 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Peptide nucleic acids (PNAs) form stable and tight complexes with complementary DNA and/or RNA and would be promising antisense reagents if their cellular delivery could be improved. We show that a 21-mer PNA, complementary to the human galanin receptor type 1 mRNA, coupled to the cellular ...
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    Science-free GM food tests advance (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 712-713 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A European Council regulation stipulating that any food product made from some maize and soya varieties containing “foreign” DNA or proteins must be labeled accordingly (Nature Biotechnology 16:605, 1998) comes into force in September. In effect, the regulation means that all soya and ...
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    Patenting DNA sequences (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 877-877 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] It is essential that all patentable subject matter be recited in the claims of a patent in order to have the most advantageous marketing position since in many startup biotechnology ventures, the patent portfolio is one of the largest and sometimes only asset. The claims located at the end of every ...
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    FISH goes with the flow (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 723-724 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The integrity of chromosome structure is essential for the maintenance of life. In particular, telomeres—stretches of repetitive DNA at the end of each of the chromosome arms—have been implicated in processes such as cell aging and transformation. The lack of a routine method for ...
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    The problem with thalidomide's new incarnation (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 695-695 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The US Food and Drug Administration's (FDA) approval of thalidomide for the treatment of Hansen's disease—once called leprosy— shows just how government and industry can work together to bring back to market a drug that, while infamous for the terrible birth defects it produced when ...
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    Errata (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 702-702 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In “Viral sequences enable efficient and tis-sue-specific expression of transgenes in Xenopus” (Nature Biotechnology 16:253–257, March 1998), the plasmid p2L contains one ITR from the left end, and one ITR from the right end of wild-type AAV, rather than two copies of the right ...
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    Patent office resurrects EST debate (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 711-711 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The debate in the US over whether broad patent claims to expressed sequence tags (ESTs)—randomly isolated fragments of DNA used mainly as probes to isolate functional genes—are patentable lives on, despite a court ruling last September that could have laid the issue to rest. The concern ...
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    Caveat browser warning on Internet IPOs (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 716-716 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Internet initial public offerings (IPOs) are the latest way for early-stage companies to raise capital without losing chunks of the company to venture capitalists or having to pay large underwriting fees associated with administering a traditional IPO. The first biotechnology company to have ...
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    Skipping a step with neural nets (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 722-723 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Theoretical studies of receptor–ligand interactions using the tihree-dimensional structure of the receptor (and possibly the ligand), and statistical mechanics or molecular dynamics methods to analyze them, suffer from two drawbacks. First, details of how macromolecules interact with each ...
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    Computer-assisted rational design of immunosuppressive compounds (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 748-752 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We describe the rational design of immunosuppressive peptides without relying on information regarding their receptors or mechanisms of action. The design strategy uses a variety of topological and shape descriptors in combination with an analysis of molecular dynamics trajectories for the ...
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    Cloning: Big business is high on the Honolulu method (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 797-797 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] When the news broke in late July that Ryuzo Yanagimachi and Teruhiko Wakayama at the University of Hawaii (Honolulu) had successfully cloned 50 mice from adult cells, it was evident to many that cloning is here to stay. Coming only 17 months after the historic cloning of Dolly the lamb in Scotland, ...
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    Latin America: ONSA, the São Paulo Virtual Genomics Institute (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 795-796 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The state of São Paulo, in Southeastern Brazil, contains approximately one-tenth of the population of Latin America and historically has been a driving force for economic development in the region. The state agency responsible for funding scientific research, known as Fundação ...
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    Cloning: On human cloning (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 798-798 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Since cloning is a human idea, and the only people (as far as is known) who are doing cloning are human people, it is interesting to me to speculate on the mind sets from which we might turn out to be working. I recall reading in a newspaper recently, among endless titillating speculations about ...
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    This Month in Nature Biotechnology (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 806-806 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The fructan beet Although identical in appearance to its non-transformed counter-part, the addition of a gene encoding 1-sucrose:sucrose fructosyl transferase has effectively created a fructan beet whose primary carbohydrates are low molecular weight fructans as opposed to sucrose (see pp. 822 and ...
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    Cloning improvements suggested (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 809-809 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The recent birth of three generations of cloned mice from an adult somatic cell by scientists at the University of Hawaii (Honolulu) suggests that cloning, or nuclear transfer and reprogramming of mammalian cells, is both possible and reproducible in species other than the sheep. Although the ...
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    Xenophobia quelled in the UK (1998)
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    Nature biotechnology 16 (1998), S. 816-816 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The UK Department of Health (London) has begun to fill a long-standing regulatory gap by announcing measures that will permit the consideration of xenotransplant clinical protocols. A public consultation on preliminary guidelines established that ‘xenotransplant regulation should have ...
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    Peptide nucleic acid smugglers (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 819-820 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Sneaking an oligonucleotide across the cell membrane is no easy task. Indeed, peptide nucleic acids (PNAs)—oligonucleotides in which the sugar-phosphate backbone has been replaced with a neutral peptide backbone—are particularly difficult to smuggle into cells, a factor that has limited ...
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    Laboratory firepower for infectious disease research (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 825-829 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Batch science machines could one day perform the work of hundreds of humans, enhancing public health surveillance, increasing experimental reproducibility, and liberating researchers from the bench so that they can focus on “big” conceptual problems. Infectious diseases pose ...
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    From bits to bases: Computing with DNA (1998)
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    Nature biotechnology 16 (1998), S. 830-832 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biocomputers could one day rival the efficiency of silicon computers for solving complex mathematical problems. The time is 2010. A busy executive at a shipping company must quickly calculate the optimum delivery routes and schedules for all his vehicles. He flicks a switch on a machine at his ...
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    Large-scale production of UDP-galactose and globotriose by coupling metabolically engineered bacteria (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 847-850 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A large-scale production system of uridine 5′-diphospho-galactose (UDP-Gal) has been established by the combination of recombinant Escherichia coli and Corynebacterium ammoniagenes. Recombinant E. coli that overexpress the UDP-Gal biosynthetic genes galT, galK, and galU were generated. C. ...
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    New Products (1998)
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    Nature biotechnology 16 (1998), S. 881-881 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Liquid handling Pipette controller Rainin's (Emeryville, CA) GlassMaster pipette controller is lightweight and easy to use with all pipettes from 1 to 100 ml; its unique mode selection switch allows the user to select between three aspirate and dispense speeds: low, full, and gravity. GlassMaster ...
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    Protein Folding: An unacknowledged problem for structural genomics? (1998)
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    Nature biotechnology 16 (1998), S. 696-696 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] It took more than 50 years, but it happened. Molecular biologists—perhaps not so quick after all—finally realized what J.D. Bernal knew all along: that protein structure was the key to biology, and the advent of structural genomics must be celebrated as the real beginning of making ...
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    Telomerase and cellular lifespan: Ending the debate? (1998)
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    Nature biotechnology 16 (1998), S. 701-702 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A recent commentary by Harry Rubin1 examined the role of telomere loss in cell aging and critically analyzed the demonstration that forced expression of telomerase can extend cell lifespan in vitro2. This was discussed with reference to human aging and cell senescence. We believe his conclusions ...
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    Business and Regulatory News (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 703-705 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Clones from adult cow Researchers from Kinki University (Osaka, Japan) andIshikawa Prefectural Livestock Research Centre (Ishikawa Prefecture, Japan) last month announced the birth of twin calves cloned from somatic cells taken from an adult cow. According to scientists from the two research ...
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    NIH panel urges technology transfer reforms (1998)
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    Nature biotechnology 16 (1998), S. 710-710 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Current negotiations over intellectual property rights are “burdensome,” and “current trends pose a serious threat” to biomedical research and development, says a Working Group on Research Tools. The panel of seven outside experts was appointed by the NIH (Bethesda, MD) to ...
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    Biotech and pharma face more costly clinical trials (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 714-714 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biotechnology and pharmaceutical companies could face longer and more costly clinical trials should recommendations in a new report issued in June by the US Department of Health and Human Services (HHS; Washington, DC) Office of the Inspector General be implemented. The report, “A Time for ...
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    Europeans hothouse genomics (1998)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 16 (1998), S. 716-717 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The research ministries of both Germany and France are attempting to stimulate plant genomics in their respective countries by establishing networks of related projects involving academic and industrial researchers on the one hand, and model and crop plants on the other. In the near future, the two ...
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