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  • Molecular Diversity Preservation International  (495,622)
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  • 1
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    A differential pressure instrument with wireless telemetry for in-situ measurement of fluid flow across sediment-water boundaries (2009)
    Molecular Diversity Preservation International
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    Publication Date: 2022-05-25
    Description: © 2009 The Authors. This article is distributed under the terms of the Creative Commons Attribution (3.0) License. The definitive version was published in Sensors 9 (2009): 404-429, doi:10.3390/s90100404.
    Description: An instrument has been built to carry out continuous in-situ measurement of small differences in water pressure, conductivity and temperature, in natural surface water and groundwater systems. A low-cost data telemetry system provides data on shore in real time if desired. The immediate purpose of measurements by this device is to continuously infer fluxes of water across the sediment-water interface in a complex estuarine system; however, direct application to assessment of sediment-water fluxes in rivers, lakes, and other systems is also possible. Key objectives of the design include both low cost, and accuracy of the order of ±0.5 mm H2O in measured head difference between the instrument’s two pressure ports. These objectives have been met, although a revision to the design of one component was found to be necessary. Deployments of up to nine months, and wireless range in excess of 300 m have been demonstrated.
    Keywords: Pressure sensor ; Wireless ; Hydrology ; Data logger ; Oceanographic instrumentation
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
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  • 2
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    Does Physical Inactivity Induce Significant Changes in Human Gut Microbiota? New Answers Using the Dry Immersion Hypoactivity Model (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Gut microbiota, a major contributor to human health, is influenced by physical activity and diet, and displays a functional cross-talk with skeletal muscle. Conversely, few data are available on the impact of hypoactivity, although sedentary lifestyles are widespread and associated with negative health and socio-economic impacts. The study aim was to determine the effect of Dry Immersion (DI), a severe hypoactivity model, on the human gut microbiota composition. Stool samples were collected from 14 healthy men before and after 5 days of DI to determine the gut microbiota taxonomic profiles by 16S metagenomic sequencing in strictly controlled dietary conditions. The α and β diversities indices were unchanged. However, the operational taxonomic units associated with the Clostridiales order and the Lachnospiraceae family, belonging to the Firmicutes phylum, were significantly increased after DI. Propionate, a short-chain fatty acid metabolized by skeletal muscle, was significantly reduced in post-DI stool samples. The finding that intestine bacteria are sensitive to hypoactivity raises questions about their impact and role in chronic sedentary lifestyles.
    Electronic ISSN: 2072-6643
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Published by Molecular Diversity Preservation International
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  • 3
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    Multicomponent Approach to the Synthesis of 4-(1H-indol-3-yl)-5-(4-methoxyphenyl)furan-2(5H)-one (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: A simple one-pot approach was developed for the synthesis of furan-2(5H)-one derivative containing indole fragments. This method includes the telescoped multicomponent reaction of indole, 4-methoxyphenylglyoxal, and Meldrum’s acid. The synthetic utility of the prepared furan-2(5H)-one was demonstrated by condensation with 4-methoxybenzaldehyde. The advantages of this method include the employment of readily accessible starting materials, atom economy, process simplicity, and the easy isolation of the target products. The structure of the synthesized furanones was confirmed by 1H and 13C-NMR spectroscopy and high-resolution mass spectrometry with electrospray ionization (ESI-HRMS).
    Electronic ISSN: 1422-8599
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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  • 4
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    Parental Book-Reading to Preterm Born Infants in NICU: The Effects on Language Development in the First Two Years (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Background: After preterm birth, infants are at high risk for delays in language development. A promising intervention to reduce this risk is represented by the exposure to parental voices through book-reading in Neonatal Intensive Care Units (NICU). This study investigated the possible advantages of book-reading to preterm neonates during their NICU stay on their subsequent language development. Methods: 100 families of preterm infants were recruited. The parents of 55 preterm infants (Reading Group) received a colored picture-book on NICU admission and were supported to read to their neonate as often as possible and to continue after hospital discharge. Forty-five infants (Control Group) were recruited before the beginning of the intervention. Infant language development was assessed with the Hearing and Language quotients of the Griffith Mental Development Scale at the corrected ages of 3, 6, 9, 12, 18 and 24 months. Results: Regardless of group membership, Hearing and Language mean quotients decreased between 9 and 18 months; nevertheless, this decrease was considerably reduced in the Reading group, compared to the Control Group. Conclusions: Reading in NICUs represents a suitable intervention that could positively influence language development and parent-infant relationships in preterm children. The study findings support its implementation as a preventive measure.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
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  • 5
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    Demand-Side Flexibility Impact on Prosumer Energy System Planning (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Apart from numerous technical challenges, the transition towards a carbon-neutral energy supply is greatly hindered by limited economic feasibility of renewable energy sources. This results in their slow and bounded penetration in both commercial and residential sectors that are responsible for over 40% of final energy consumption. This paper aims to demonstrate that combined application of sophisticated planning methodologies at building-level and presents incentive mechanisms for renewables that can result in prosumers, featuring hybrid renewable energy systems (HRES), with economic performance comparable to that of conventional energy systems. The presented research enhances existing planning methodologies by integrating appliance-level demand side management into the decision process and investigates its effect on the planning problem. Moreover, the proposed methodology features an innovative and holistic approach that simultaneously assess electrical and thermal domain in both an isolated and grid-connected context. The analyzed hybrid system consists of solar photovoltaic, wind turbine and battery with thermal supply featuring solar thermal collector and a ground-source heat pump. Overall optimization problem is modeled as a mixed-integer linear program, while ranking of all feasible alternatives is made by the multicriteria decision-making algorithm against several technological, economic, and environmental criteria. A real-life scenario of energy system retrofit for a building in the United Kingdom was employed to demonstrate overall cost savings of 12% in the present market and regulation context.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 6
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    Real-Time 2-D Lidar Odometry Based on ICP (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: This study presents a 2-D lidar odometry based on an ICP (iterative closest point) variant used in a simple and straightforward platform that achieves real-time and low-drift performance. With a designated multi-scale feature extraction procedure, the lidar cloud information can be utilized at multiple levels and the speed of data association can be accelerated according to the multi-scale data structure, thereby achieving robust feature extraction and fast scan-matching algorithms. First, on a large scale, the lidar point cloud data are classified according to the curvature into two parts: smooth collection and rough collection. Then, on a small scale, noise and unstable points in the smooth or rough collection are filtered, and edge points and corner points are extracted. Then, the proposed tangent-vector-pairs based on edge and corner points are applied to evaluate the rotation term, which is significant for producing a stable solution in motion estimation. We compare our performance with two excellent open-source SLAM algorithms, Cartographer and Hector SLAM, using collected and open-access datasets in structured indoor environments. The results indicate that our method can achieve better accuracy.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
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  • 7
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    ArcheoBot Experimental Tools for Archaeology and Cultural Heritage (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: ArcheoBot is a prototype of a Telegram Bot: it is an experimental prototype that builds on the common digital experiences of the authors of this article, aiming to offer a quick, powerful, easy to use tool. It aims to serve archaeological and topographical investigations quickly and to interface with other software for the management of collected data.
    Electronic ISSN: 2673-4931
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 8
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    Solvent and pH Stability of Poly(styrene-alt-maleic acid) (PSaMA) Membranes Prepared by Aqueous Phase Separation (APS) (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: In the single-polyelectrolyte aqueous phase separation (APS) approach, membranes are prepared by precipitating a weak polyelectrolyte from a concentrated aqueous solution using a pH switch. This has proven to be a versatile and more sustainable method compared to conventional approaches as it significantly reduces the use of organic solvents. Poly(styrene-alt-maleic acid) (PSaMA) is a polymer that has been extensively investigated for APS and has been the basis for both open and dense membranes with good performances. These membranes are chemically crosslinked and, in this work, we further investigated ultrafiltration (UF) and nanofiltration (NF) membranes prepared with PSaMA for their stability in various organic solvents and under different pH conditions. It was shown that these membranes had stable performances in both isopropanol (IPA) and toluene, and a slightly reduced performance in N-methyl-2-pyrollidone (NMP). However, PSaMA did not perform well as a selective layer in these solvents, indicating that the real opportunity would be to use the UF-type PSaMA membranes as solvent-stable support membranes. Additionally, the membranes proved to be stable in an acidic-to-neutral pH regime (pH 2–7); and, due to the pH-responsive nature of PSaMA, for the NF membranes, a pH-dependent retention of Mg2+ and SO42− ions was observed and, for the UF membranes, a strong responsive behavior was observed, where the pH can be used to control the membrane permeability. However, long-term exposure to elevated pH conditions (pH 8–10) resulted in severe swelling of the NF membranes, resulting in defect formation, and compaction of the UF membranes. For the UF membranes, this compaction did prove to be reversible for some but not all of the membrane samples measured. These results showed that in aqueous systems, membranes prepared with PSaMA had interesting responsive behaviors but performed best at neutral and acidic pH values. Moreover, the membranes exhibited excellent stability in the organic solvents IPA and toluene
    Electronic ISSN: 2077-0375
    Topics: Biology , Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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  • 9
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    Effects of Stand Structure and Topography on Forest Vegetation Carbon Density in Jiangxi Province (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Stand structure and topography are important factors affecting forest vegetation carbon density (FVCD). Revealing the interaction mechanisms between stand structure and topography on FVCD is of great significance for enhancing forest vegetation carbon storage and achieving regional carbon neutrality. Based on stratified sampling, systematic distribution and forest continuous inventory sample plots in Jiangxi province, the variation characteristics of FVCD and its correlations with stand structure and topographic factors were studied. The results are as follows: (1) The average FVCD in Jiangxi province was 44.23 Mg/ha, which was dominated by the carbon density of the arbor layer, accounting for about 81.39% of the total forest—far lower than the average level of global FVCD, which proved that the forest in Jiangxi province was dominated by middle-age and young forests with low carbon density, and also showed that the potential for forest vegetation carbon storage in Jiangxi province was huge. (2) Except for vegetation carbon densities of shrub and herb layers, the vegetation carbon densities of other forest layers in Jiangxi province were significantly different among different forest types. Volume per unit area was the most important factor affecting the vegetation carbon densities of arbor and total forest, and vegetation carbon density–volume models of the main forests were built for vegetation carbon density calculation in Jiangxi province. (3) The vegetation carbon densities of arbor layer, snag and log layer, and total forest increased significantly with increases in elevation and slope. Except for the shrub layer and herb layer, the vegetation carbon densities of the other layers and the total forest had extremely significant or significant differences between slope position gradients—indicating that the effect of topography on FVCD in Jiangxi province was significant, mainly through influencing of forest distribution and human disturbance intensity.
    Electronic ISSN: 1999-4907
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Molecular Diversity Preservation International
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  • 10
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    On Sustainable Consumption: The Implications of Trade in Virtual Water for the EU’s Food Security (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: The paper addresses the sustainability of the European Union’s food consumption through a water footprint assessment of selected vulnerable agricultural imports from a two-pronged perspective: (1) the degree of the EU’s dependence on global green water resources embedded in the apparent consumption of selected water-intensive agricultural products and (2) the degree of commitment of countries of origin to sustainability policies. The study argues that the vulnerability of the EU’s agricultural imports to water risks can be estimated based on the amount of green water consumed in producing crops in the countries of origin. The results show that the EU’s consumption of agricultural goods is highly dependent on virtual water imports for all six selected vulnerable agricultural products, from the lowest footprint for bananas (5 mil. km3) to the largest for coffee (69 mil. km3). The analysis also points to a greater concern for quality issues in the countries of origin (56.53%) relative to management (26.52%) and availability issues (16.85%), but the latter are to arise in importance for sustainable production in the years to come. Our conclusions contribute to building up a responsible commitment towards (1) development of environmental policies and the design of practical measures by providing quantitative information that makes problems more clearly defined and tangible, and (2) assessing the outcome of policies and practical measures by understanding their effects on the sustainability of food consumption.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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  • 11
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    Understanding the High Creep Resistance of MRI 230D Magnesium Alloy through Nanoindentation and Atom Probe Tomography (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Due to their low density, magnesium alloys are very appealing for light-weight constructions. However, the use of the most common magnesium alloy, AZ91 (Mg 9 wt.% Al, 1 wt.% Zn), is limited to temperatures below 150 °C due to creep failure. Several alloys with an improved creep resistance have been developed in the past, for example the alloy MRI 230D or Ca-alloyed AZ91 variants. However, there is an ongoing discussion in the literature regarding the mechanisms of the improved creep resistance. One factor claimed to be responsible for the improved creep resistance is the intermetallic phases which form during casting. Another possible explanation is an increased creep resistance due to the formation of precipitates. To gain more insight into the improved creep resistance of MRI 230D, nanoindentation measurements have been performed on the different phases of as-cast, creep-deformed and heat-treated samples of MRI 230D and Ca-alloyed AZ91 variants. These nanoindentation measurements clearly show that the intermetallic phase (IP) of the alloy MRI 230D does not lose strength during creep deformation in contrast to the Ca-alloyed AZ91 variants. High-temperature nanoindentation measurements performed at 200 °C clearly show that the intermetallic phases of the MRI 230D alloy maintain their strength. This is in clear contrast to the Ca-alloyed AZ91 variants, where the IP is significantly softer at 200 °C than at room temperature. Atom probe measurements have been used to gain insight into the differences in terms of chemical composition between the IPs of MRI 230D and the Ca-alloyed AZ91 variants in order to understand the dissimilar behaviour in terms of strength loss with increasing temperature.
    Electronic ISSN: 2075-4701
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 12
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    FaTEMa: A Framework for Multi-Layer Fault Tolerance in IoT Systems (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Fault tolerance in IoT systems is challenging to overcome due to its complexity, dynamicity, and heterogeneity. IoT systems are typically designed and constructed in layers. Every layer has its requirements and fault tolerance strategies. However, errors in one layer can propagate and cause effects on others. Thus, it is impractical to consider a centralized fault tolerance approach for an entire system. Consequently, it is vital to consider multiple layers in order to enable collaboration and information exchange when addressing fault tolerance. The purpose of this study is to propose a multi-layer fault tolerance approach, granting interconnection among IoT system layers, allowing information exchange and collaboration in order to attain the property of dependability. Therefore, we define an event-driven framework called FaTEMa (Fault Tolerance Event Manager) that creates a dedicated fault-related communication channel in order to propagate events across the levels of the system. The implemented framework assist with error detection and continued service. Additionally, it offers extension points to support heterogeneous communication protocols and evolve new capabilities. Our empirical results show that introducing FaTEMa provided improvements to the error detection and error resolution time, consequently improving system availability. In addition, the use of Fatema provided a reliability improvement and a reduction in the number of failures produced.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
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  • 13
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    An Integrated of Hydrogen Fuel Cell to Distribution Network System: Challenging and Opportunity for D-STATCOM (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: The electric power industry sector has become increasingly aware of how counterproductive voltage sag affects distribution network systems (DNS). The voltage sag backfires disastrously at the demand load side and affects equipment in DNS. To settle the voltage sag issue, this paper achieved its primary purpose to mitigate the voltage sag based on integrating a hydrogen fuel cell (HFC) with the DNS using a distribution static synchronous compensator (D-STATCOM) system. Besides, this paper discusses the challenges and opportunities of D-STATCOM in DNS. In this paper, using HFC is well-designed, modeled, and simulated to mitigate the voltage sag in DNS with a positive impact on the environment and an immediate response to the issue of the injection of voltage. Furthermore, this modeling and controller are particularly suitable in terms of cost-effectiveness as well as reliability based on the adaptive network fuzzy inference system (ANFIS), fuzzy logic system (FLC), and proportional–integral (P-I). The effectiveness of the MATLAB simulation is confirmed by implementing the system and carrying out a DNS connection, obtaining efficiencies over 94.5% at three-phase fault for values of injection voltage in HFC D-STATCOM using a P-I controller. Moreover, the HFC D-STATCOM using FLC proved capable of supporting the network by 97.00%. The HFC D-STATCOM based ANFIS proved capable of supporting the network by 98.00% in the DNS.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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  • 14
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    Dynamics of Charged Particles Moving around Kerr Black Hole with Inductive Charge and External Magnetic Field (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: We mainly focus on the effects of small changes of parameters on the dynamics of charged particles around Kerr black holes surrounded by an external magnetic field, which can be considered as a tidal environment. The radial motions of charged particles on the equatorial plane are studied via an effective potential. It is found that the particle energies at the local maxima values of the effective potentials increase with an increase in the black hole spin and the particle angular momenta, but decrease with an increase of one of the inductive charge parameter and magnetic field parameter. The radii of stable circular orbits on the equatorial plane also increase, whereas those of the innermost stable circular orbits decrease. On the other hand, the effects of small variations of the parameters on the orbital regular and chaotic dynamics of charged particles on the non-equatorial plane are traced by means of a time-transformed explicit symplectic integrator, Poincaré sections and fast Lyapunov indicators. It is shown that the dynamics sensitivity depends on small variations in the inductive charge parameter, magnetic field parameter, energy, and angular momentum. Chaos occurs easily as each of the inductive charge parameter, magnetic field parameter, and energy increases but is weakened as the angular momentum increases. When the dragging effects of the spacetime increase, the chaotic properties are not always weakened under some circumstances.
    Electronic ISSN: 2218-1997
    Topics: Physics
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  • 15
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    Effect of Drilling Fluid Invasion on Natural Gas Hydrate Near-Well Reservoirs Drilling in a Horizontal Well (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Horizontal wells can significantly improve the gas production and are expected to be an efficient exploitation method for the industrialization of natural gas hydrates (NGHs) in the future. However, the near-wellbore hydrate is highly prone to decomposition during the drilling process, owing to the disturbance aroused by the factors such as the drilling fluid temperature, pressure, and salinity. These issues can result in the engineering accidents such as bit sticking and wellbore instability, which are required for further investigations. This paper studies the characteristics of drilling fluid invasion into the marine NGH reservoir with varied drilling fluid parameters via numerical simulation. The effects of the drilling fluid parameters on the decomposition behavior of near-wellbore hydrates are presented. The simulating results show that the adjustments of drilling fluid density within the mud safety window have limited effects on the NGH decomposition, meanwhile the hydrates reservoir is most sensitive to the drilling fluid temperature variation. If the drilling fluid temperature grows considerably due to improper control, the range of the hydrates decomposition around the horizontal well tends to expand, which then aggravates wellbore instability. When the drilling fluid salinity varies in the range of 3.5–7.5%, the increase in the ion concentration speeds up the hydrate decomposition, which is adverse to maintaining wellbore stability.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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  • 16
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    A Vision-Based Approach for the Analysis of Core Characteristics of Volcanic Ash (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-29
    Description: Volcanic ash fall-out represents a serious hazard for air and road traffic. The forecasting models used to predict its time–space evolution require information about the core characteristics of volcanic particles, such as their granulometry. Typically, such information is gained by the spot direct observation of the ash collected at the ground or by using expensive instrumentation. In this paper, a vision-based methodology aimed at the estimation of ash granulometry is presented. A dedicated image processing paradigm was developed and implemented in LabVIEW™. The methodology was validated experimentally using digital reference images resembling different operating conditions. The outcome of the assessment procedure was very encouraging, showing an accuracy of the image processing algorithm of 1.76%.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
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  • 17
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    A Novel Approach for the Design of Fast-Settling Amplifiers for Biosignal Detection (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The most common method used to pick up biomedical signals is through metallic electrodes coupled to the input of high-gain, low-noise amplifiers. Unfortunately, electrodes, amongst other effects, introduce an undesired contact resistance and a contact potential. The contact potential needs to be rejected since it would otherwise cause the saturation of the input stage of the amplifiers, and this is almost always obtained by inserting a simple RC high-pass filter in the input signal path. The contact resistance needs to be estimated to ensure that it does not impair correct measurements. Methods exist for estimating the contact resistance by dynamically modifying the input network configuration, but because of the presence of the input RC filter, long transients are induced any time a switch occurs between different input configurations, so that the measurement time may become unacceptably long. In this paper, we propose a new topology for a DC removal network at the input of the differential signal amplifier that results in an AC filter whose time constant can be continuously changed by means of a control voltage. As such, we can speed up the recovery from transients by setting very short time constants (during the input resistance estimation process) while maintaining the ability to obtain very low cut-in frequencies by setting a much larger time constant during actual measurements. A prototype of the system was built and tested in order to demonstrate the advantage of the approach we propose in terms of reduced measurement time.
    Electronic ISSN: 2079-9292
    Topics: Electrical Engineering, Measurement and Control Technology
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  • 18
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    Labeling of Installed Heating Appliances in Residential Buildings: An Energy Labeling Methodology for Improving Consumers’ Awareness (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: In the EU 28, the installed heating appliance stock is quite old, with an actual replacement rate of 4%. This is directly reflected in the average efficiency of the installed heating systems, where around 60% of the stock is rated with an energy class of C or D (the lowest classes of the energy label scale). The European project HARP aims at raising consumers’ awareness of the planned replacement of their old and inefficient heating appliances with more efficient and renewable solutions. In this direction, an energy labeling methodology for old appliances has been developed to rate the installed stock before the introduction of the EU energy label. The methodology has been developed for space heating appliances and water heaters, targeting two types of users: end consumers and professional users. The validation considered about 4600 space heating appliances and 800 water heaters built between 1972 and 2019. Three heating appliances and two water heaters were tested in the laboratory, confirming the reliability of the proposed methodology. The expected impact of defining an energy labeling methodology for installed heating appliances increases the current replacement rate of these appliances in the EU from 4% to 5%.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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  • 19
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    A Comprehensive Harmonic Analysis of Current-Mode Power Amplifiers (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: This work presents a comprehensive theoretical analysis of current-mode power amplifiers as a function of input power for different biasing classes under the common simplifying assumption of constant transconductance and hard current cut-off/saturation. Typically, the theoretical analysis of power amplifier performance and behavior are carried out only at maximum output power. However, to achieve high data-rates, modern telecommunication systems adopt signals characterized by a very high peak-to-average power ratio, thus it is useful to analyze the power amplifier behavior as a function of power back-off. Moreover, in many cases, to enhance the efficiency and/or to apply harmonic shaping techniques, a clipped drain-source current, which approaches a square wave, is required. The classical analysis can be extended to low power levels only under the assumption of power-independent conduction angle, which is true only for class-A and class-B amplifiers, and does not take into account possible waveform clipping at maximum current. This work presents a complete theoretical Fourier analysis of FET-based power amplifiers as a function of quiescent drain-source current at any input power level and accounting for the clipped current case, up to the square-wave limit, reorganizing and completing the material that can be found in classical textbooks in the field.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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  • 20
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    Increased Post-Hypoxic Oxidative Stress and Activation of the PERK Branch of the UPR in Trap1-Deficient Drosophila melanogaster Is Abrogated by Metformin (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Hypoxia is known to impair mitochondrial and endoplasmic reticulum (ER) homeostasis. Post-hypoxic perturbations of the ER proteostasis result in the accumulation of misfolded/unfolded proteins leading to the activation of the Unfolded Protein Response (UPR). Mitochondrial chaperone TNF receptor-associated protein 1 (TRAP1) is reported to preserve mitochondrial membrane potential and to impede reactive oxygen species (ROS) production thereby protecting cells from ER stress as well as oxidative stress. The first-line antidiabetic drug Metformin has been attributed a neuroprotective role after hypoxia. Interestingly, Metformin has been reported to rescue mitochondrial deficits in fibroblasts derived from a patient carrying a homozygous TRAP1 loss-of-function mutation. We sought to investigate a putative link between Metformin, TRAP1, and the UPR after hypoxia. We assessed post-hypoxic/reperfusion longevity, mortality, negative geotaxis, ROS production, metabolic activity, gene expression of antioxidant proteins, and activation of the UPR in Trap1-deficient flies. Following hypoxia, Trap1 deficiency caused higher mortality and greater impairments in negative geotaxis compared to controls. Similarly, post-hypoxic production of ROS and UPR activation was significantly higher in Trap1-deficient compared to control flies. Metformin counteracted the deleterious effects of hypoxia in Trap1-deficient flies but had no protective effect in wild-type flies. We provide evidence that TRAP1 is crucially involved in the post-hypoxic regulation of mitochondrial/ER stress and the activation of the UPR. Metformin appears to rescue Trap1-deficiency after hypoxia mitigating ROS production and downregulating the pro-apoptotic PERK (protein kinase R-like ER kinase) arm of the UPR.
    Print ISSN: 1661-6596
    Electronic ISSN: 1422-0067
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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    Identification of Reference Genes for Expression Studies in the Whole-Blood from Three Cattle Breeds under Two States of Livestock Weather Safety (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Real-time PCR is widely used to study the relative abundance of mRNA due to its specificity, sensitivity, and repeatability quantification. However, relative quantification requires a reference gene, which should be stable in its expression, showing lower variation by experimental conditions or tissues. The aim of this study was to evaluate the stability of the expression of five commonly used reference genes (actb, ywhaz, b2m, sdha, and 18s rRNA) at different physiological stages (alert and emergency) in three different cattle breeds. In this study, five genes (actb, ywhaz, b2m, sdha, and 18s rRNA) were selected as candidate reference genes for expression studies in the whole blood from three cattle breeds (Romosinuano, Gyr, and Brahman) under heat stress conditions. The transcription stability of the candidate reference genes was evaluated using geNorm and NormFinder. The results showed that actb, 18SrRNA, and b2m expression were the most stable reference genes for whole blood of Gyr and Brahman breeds under two states of livestock weather safety (alert and emergency). Meanwhile, actb, b2m, and ywhaz were the most stable reference genes for the Romosinuano breed.
    Electronic ISSN: 2076-2615
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
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    Poor Ventilation Habits in Nursing Homes Have Favoured a High Number of COVID-19 Infections (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Residents of nursing homes have been significantly affected by COVID-19 in Spain. The factors that have contributed to the vulnerability of this population are very diverse. In this study, physical agents, chemical pollutants, population density and different capacities of residences were analysed to understand their influence on the number of elderly people who have died in geriatric centres in different autonomous communities (AACCs) of Spain. A statistical analysis was carried out on the variables observed. The results show that many residences with a larger number of deaths were private, with some exceptions. Physical agents and pollutants were found to be determining factors, especially for the communities of Extremadura and Castilla–La Mancha, although the large number of factors involved makes this study complicated. The compromise between air quality and energy efficiency is of great importance, especially when human health is at stake.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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    Energy Self-Sufficient Livestock Farm as the Example of Agricultural Hybrid Off-Grid System (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Contemporary agriculture has become very energy-intensive and mainly uses electricity, which is needed for technological processes on livestock farms. Livestock faeces are burdensome for the environment due to the release of methane into the atmosphere. This article presents the concept of a self-sufficient livestock farm as an off-grid energy circuit that is a part of the agricultural process. The key idea is to obtain an energy flow using the concept of a smart valve to achieve a self-sufficient energy process based on a biogas plant, renewable energy sources, and energy storage. During the production process, a livestock farm produces large amounts of waste in the form of grey and black manure. On the one hand, these products are highly harmful to the environment, but on the other, they are valuable input products for another process, i.e., methane production. The methane becomes the fuel for cogeneration generators that produce heat and electricity. Heat and electricity are partly returned to the main farming process and partly used by residents of the area. In this way, a livestock farm and the inhabitants of a village or town can become energy self-sufficient and independent of national grids. The idea described in this paper shows the process of energy production combining a biogas plant, renewable energy sources, and an energy storage unit that enable farmland to become fully self-sufficient through the energy flow between all constituents of the energy cycle being maintained by a smart valve.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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    SCADA Data-Based Working Condition Classification for Condition Assessment of Wind Turbine Main Transmission System (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Due to the complex and variable conditions under which wind turbines operate, existing working condition classification methods are inadequate for condition assessment of the main transmission system. Because working conditions are too few after classification, it cannot effectively describe the complex and variable working conditions of wind turbine. This can lead to high false-alarm rates in the condition monitoring, which affect normal operations. This paper proposes a working condition classification method for the main transmission system of wind turbines based on supervisory control and data acquisition (SCADA) data. Firstly, correlation analysis of SCADA data acquired by wind farm is used to select the parameters relevant to the main transmission system. Secondly, according to the wind turbine control principle, the working conditions are initially divided into four phases: shutdown, start-up, maximum wind energy tracking, and constant speed. The k-means clustering algorithm is used to subdivide the maximum wind energy-tracking phase and constant speed phase, which account for a larger proportion of the working conditions, to achieve better classification. Finally, a case study is used to demonstrate the calculation of alarm thresholds and alarm rates for each working condition. The results are compared with the direct use of k-means clustering for working condition classification. It is concluded that the proposed method can significantly reduce the false-alarm rate of the vibration detection process.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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    Land Use Change and Its Impact on Landscape Ecological Risk in Typical Areas of the Yellow River Basin in China (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The basic premise of regional ecological construction would be to scientifically and effectively grasp the characteristics of land use change and its impact on landscape ecological risk. The research objects of this paper are the typical areas of the Yellow River Basin in China and “process-change-drive” as the logical main line. Moreover, this paper is based on multi-period land use remote sensing data from 2000 to 2020, the regional land use change process and influencing factors are identified, the temporal and spatial evolution and response process of landscape ecological risk are discussed, and the land use zoning control strategy to reduce ecological risk is put forward. The results indicated: (1) The scale and structure of land use show the characteristics of “many-to-one” and “one-to-many”; (2) the process of land use change is affected by the alternation of multiple factors. The natural environment and socio-economic factors dominate in the early stage and the location and policy factors have a significant impact in the later stage; (3) the overall landscape ecological risk level and conversion rate show a trend of “high in the southeast, low in the northwest”, shift from low to high and landscape ecological risks gradually increase; and (4) in order to improve the regional ecological safety and according to the characteristics of landscape ecological risk and spatial heterogeneity, we should adopt the management and control zoning method and set different levels of control intensity (from key intensity to strict intensity to general intensity), and develop differentiated land use control strategies.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
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    An Energy-Friendly Scheduler for Edge Computing Systems (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The deployment of modern applications, like massive Internet of Things (IoT), poses a combination of challenges that service providers need to overcome: high availability of the offered services, low latency, and low energy consumption. To overcome these challenges, service providers have been placing computing infrastructure close to the end users, at the edge of the network. In this vein, single board computer (SBC) clusters have gained attention due to their low cost, low energy consumption, and easy programmability. A subset of IoT applications requires the deployment of battery-powered SBCs, or clusters thereof. More recently, the deployment of services on SBC clusters has been automated through the use of containers. The management of these containers is performed by orchestration platforms, like Kubernetes. However, orchestration platforms do not consider remaining energy levels for their placement decisions and therefore are not optimized for energy-constrained environments. In this study, we propose a scheduler that is optimised for energy-constrained SBC clusters and operates within Kubernetes. Through comparison with the available schedulers we achieved 23% fewer event rejections, 83% less deadline violations, and approximately a 59% reduction of the consumed energy throughout the cluster.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by Molecular Diversity Preservation International
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    Inorganic Fertilization at High N Rate Increased Olive Yield of a Rainfed Orchard but Reduced Soil Organic Matter in Comparison to Three Organic Amendments (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Strategies for waste valorisation from domestic and agro-industrial activities must be pursued, and its use as a soil amendment is an interesting possibility. In this four-year study, the effect of applying municipal solid waste (MSW), farmyard manure (FYM), bottom wood ash supplemented with nitrogen (Ash + N), the inorganic fertilization common in the region (50 kg ha-1 N, P2O5 and K2O) (Control) and this inorganic fertilization supplemented with 70 kg N ha-1 (High N) was assessed in a rainfed olive grove planted in a shallow soil with low organic matter and managed with conventional tillage. The High N treatment significantly increased olive yield in comparison to the other treatments (165% more than MSW), and soil available N proved to be the main driver for tree productivity. MSW and FYM increased soil organic matter, as well as the levels of phosphorus and cation exchange capacity, leaving good indications for future production cycles, although during the four years of the study these treatments provided little N to the trees. The High N treatment significantly reduced soil organic matter (63% less than MSW). The result was attributed in part to the soil management system that did not allow the development of herbaceous vegetation, but also to an effect known as “added N interaction”, in which the excess of inorganic N in the soil might have contributed to accelerate the mineralization of native soil organic matter, an aspect that compromises the sustainability of this fertilization strategy. Although MSW and wood ash are sometimes associated with risks of environmental contamination with heavy metals, in this study the levels of heavy metals in soils and in plant tissues were not of concern.
    Electronic ISSN: 2073-4395
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Economics
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    Evaluation of Drainage Water Detention Efficiency of Off-Line Ditch-Pond Systems and Its Influencing Factors (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Ditch-pond systems can effectively alleviate the adverse effects of agricultural drainage on downstream canals and flood control in downstream areas. In this study, peak flow reduction rate (PFR) and drainage volume detention rate (DVD) are used to evaluate the effectiveness of an off-line ditch-pond system for reducing peak flow, retarding agricultural drainage water, and examining the key influencing factors. The results show that the PFR and DVD of the off-line ditch-pond system are significantly affected by three parameters: weir depth (Ld), weir width (Lw), and pond area-to-drainage area ratio (Ksp). Both the PFR and DVD increase with the increase in Ld, Lw, and Ksp. The effects of Ld and Lw on the PFR and the DVD are significant, whereas that Ksp is relatively small. Adjusting Ld and Lw increases both the PFR and DVD up to 80%. Specifically, Ld contributes 75% of the variations in the PFR and the DVD, and Lw affects only 17% of the PFR variations and 11% of the DVD variations. These findings confirm that an off-line ditch-pond system can be effectively used for the detention of agricultural drainage water. Thus, when such a system is designed with an appropriate diversion weir, the impact of agricultural drainage water on downstream canals and downstream areas can be reduced remarkably.
    Electronic ISSN: 2073-4441
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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    Using a Two-Stage Method to Reject False Loop Closures and Improve the Accuracy of Collaborative SLAM Systems (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Loop-closure detection is an essential means to reduce accumulated errors of simultaneous localization and mapping (SLAM) systems. However, even false positive loop closures could seriously interfere and even corrupt the back-end optimization process. For a collaborative SLAM system that generally uses both intra-robot and inter-robot loop closures to optimize the pose graph, it is a tough job to reject those false positive loop closures without a reliable a priori knowledge of the relative pose transformation between robots. Aiming at this solving problem, this paper proposes a two-stage false positive loop-closure rejection method based on three types of consistency checks. Firstly, a multi-robot pose-graph optimization model is given which transforms the multi-robot pose optimization problem into a maximum likelihood estimation model. Then, the principle of the false positive loop-closure rejection method based on test is proposed, in which clustering is used to reject those intra-robot false loop-closures in the first step, and a largest mutually consistent loop-based test is constructed to reject inter-robot false loop closures in the second step. Finally, an open dataset and synthetic data are used to evaluate the performance of the algorithms. The experimental results demonstrate that our method improves the accuracy and robustness of the back-end pose-graph optimization with a strong ability to reject false positive loop closures, and it is not sensitive to the initial pose at the same time. In the Computer Science and Artificial Intelligence Lab (CSAIL) dataset, the absolute position error is reduced by 55.37% compared to the dynamic scaling covariance method, and the absolute rotation error is reduced by 77.27%; in the city10,000 synthetic dataset, the absolute position error is reduced by 89.37% compared to the pairwise consistency maximization (PCM) and the absolute rotation error is reduced by 97.9%.
    Electronic ISSN: 2079-9292
    Topics: Electrical Engineering, Measurement and Control Technology
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    Nicotinamide N-Methyltransferase in Head and Neck Tumors: A Comprehensive Review (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The head and neck tumors (HNT) are a heterogeneous group of diseases ranging from benign to malignant lesions, with distinctive molecular and clinical behaviors. Several studies have highlighted the presence of an altered metabolic phenotype in HNT, such as the upregulation of nicotinamide N-methyltransferase (NNMT). However, its biological effects have not been completely disclosed and the role of NNMT in cancer cell metabolism remains unclear. Therefore, this comprehensive review aims to evaluate the available literature regarding the biological, diagnostic, and prognostic role of NNMT in HNT. NNMT was shown to be significantly overexpressed in all of the evaluated HNT types. Moreover, its upregulation has been correlated with cancer cell migration and adverse clinical outcomes, such as high-pathological stage, lymph node metastasis, and locoregional recurrences. However, in oral squamous cell carcinoma (OSCC) these associations are still debated, and several studies have failed to demonstrate the prognostic significance of NNMT. The shRNA-mediated gene silencing efficiently suppressed the NNMT gene expression and exhibited a clear inhibitory effect on cell proliferation, promoting the expression of apoptosis-related proteins and modulating the cell cycle. NNMT could represent a new molecular biomarker and a new target of molecular-based therapy, although further studies on larger patient cohorts are needed to explore its biological role in HNT.
    Electronic ISSN: 2218-273X
    Topics: Biology
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    Seasonal and Temporal Influence on Polycyclic Aromatic Hydrocarbons in the Red Sea Coastal Water, Egypt (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: This study investigated seasonal variation, spatial distribution, sources, composition and potential ecological risks of 16 polycyclic aromatic hydrocarbons (PAHs) in Red Sea coastal water. Surface seawater samples were collected at fourteen different locations. The sum of 16 PAHs concentrations in Red Sea showed clear variation between seasons, ranged from 1.08–6.10, 0.79–50.86, 1.37–54.47 and 0.21–7.18 μg/L in summer, autumn, winter, and spring respectively. PAHs levels in Red Sea coastal waters were relatively high at certain sites during autumn and winter seasons. They could be classified as highly polluted by PAHs contaminants (〉10 μg/L). According to the diagnostic ratios measured, the majority of PAHs in this study originated from pyrogenic sources, while minor amounts originated from petrogenic sources. Four rings PAHs accounted for more than 64% of the total PAHs studied. PAHs pose a high ecological risk along the period of study, according to the ecological risk assessment by Risk quotients (RQNCs and RQMPCs).
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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    Convolutional Autoencoding and Gaussian Mixture Clustering for Unsupervised Beat-To-Beat Heart Rate Estimation of Electrocardiograms from Wearable Sensors (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Heart rate is one of the most important diagnostic bases for cardiovascular disease. This paper introduces a deep autoencoding strategy into feature extraction of electrocardiogram (ECG) signals, and proposes a beat-to-beat heart rate estimation method based on convolution autoencoding and Gaussian mixture clustering. The high-level heartbeat features were first extracted in an unsupervised manner by training the convolutional autoencoder network, and then the adaptive Gaussian mixture clustering was applied to detect the heartbeat locations from the extracted features, and calculated the beat-to-beat heart rate. Compared with the existing heartbeat classification/detection methods, the proposed unsupervised feature learning and heartbeat clustering method does not rely on accurate labeling of each heartbeat location, which could save a lot of time and effort in human annotations. Experimental results demonstrate that the proposed method maintains better accuracy and generalization ability compared with the existing ECG heart rate estimation methods and could be a robust long-time heart rate monitoring solution for wearable ECG devices.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
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    Identification and Fine Mapping of a Locus Related to Leaf Up-Curling Trait (Bnuc3) in Brassica napus (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Leaf trait is an important target trait in crop breeding programs. Moderate leaf curling may be a help for improving crop yield by minimizing the shadowing by leaves. Mining locus for leaf curling trait is of significance for plant genetics and breeding researches. The present study identified a novel rapeseed accession with up-curling leaf, analyzed the up-curling leaf trait inheritance, and fine mapped the locus for up-curling leaf property (Bnuc3) in Brassica napus. Genetic analysis revealed that the up-curling leaf trait is controlled by a single dominant locus, named BnUC3. We performed an association study of BnUC3 with single nucleotide polymorphism (SNP) markers using a backcross population derived from the homozygous up-curling leaf line NJAU-M1295 and the canola variety ‘zhongshuang11’ with typical flat leaves, and mapped the BnUC3 locus in a 1.92 Mb interval of chromosome A02 of B. napus. To further map BnUC3, 232 simple sequence repeat (SSR) primers and four pairs of Insertion/Deletion (InDel) primers were developed for the mapping interval. Among them, five SSR markers and two InDel markers were polymorphic. By these markers, the mapping interval was narrowed to 92.0 kb using another F2 population. This fine mapping interval has 11 annotated genes among which BnaA02T0157000ZS were inferred to be candidate casual genes for up-curling leaf based on the cloned sequence analysis, gene functionality, and gene expression analysis. The current study laid a foundational basis for further elucidating the mechanism of BnUC3 and breeding of variety with up-curling leaf.
    Print ISSN: 1661-6596
    Electronic ISSN: 1422-0067
    Topics: Chemistry and Pharmacology
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    Characteristics of the Polyphenolic Profile and Antioxidant Activity of Cone Extracts from Conifers Determined Using Electrochemical and Spectrophotometric Methods (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The aim of the study was to analyze the polyphenolic profile of cone extracts of Douglas fir, Scots pine and Korean fir, and to study their antioxidant activity. The mechanism of electro-oxidation of polyphenols (such as procyanidins and catechins) from cone extracts was investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV), as well as spectrophotometric methods—ABTS (2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonate)), DPPH (2,2-diphenyl-1-picrylhydrazyl), FRAP (Ferric Reducing Antioxidant Power ) and CUPRAC (CUPric Reducing Antioxidant Capacity). The scientific novelty of the research is the comprehensive analysis of cone extracts in terms of antioxidant properties. Due to the high polyphenol content, the extracts showed significant ability to reduce oxidative reactions, as well as the ability to scavenge free radicals and transition metal ions. Douglas fir, Scots pine and Korean fir cone extracts can potentially be used as natural stabilizers, preservatives and antimicrobial substances in the food industry and in medications.
    Electronic ISSN: 2076-3921
    Topics: Chemistry and Pharmacology
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    An Approach to Delineate Potential Groundwater Zones in Kilinochchi District, Sri Lanka, Using GIS Techniques (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The scarcity of surface water resources in the dry season in the Kilinochchi district increases the demand for freshwater. Therefore, the main objective of this study is to delineate potential groundwater zones in Kilinochchi, Sri Lanka, using integrated remote sensing (RS), geographic information systems (GIS) and the analytical hierarchy process (AHP). Groundwater potential zones are demarcated for the Kilinochchi district by overlaying thematic layers: geology, geomorphology, land use/land cover, soil types, drainage density, slope, lineament, and rainfall. The thematic layers were integrated into a geographic information system, and a weighted overlay analysis was carried out to delineate groundwater zones. Thus the resultant map is categorized into five different potential zones: very low (59.12 km2), low (207.78 km2), moderate (309.89 km2), high (507.74 km2), and very high (111.26 km2). The groundwater potential map was validated with the existing seventy-nine wells, which indicated a good prediction accuracy of 81.8%. This suggests that the results obtained by integrating RS-GIS and AHP are well-matched with the existing well water depth. The AHP approach based on RS-GIS was a handy and efficient technique for assessing potential groundwater zones. This research will help policymakers better manage the Kilinochchi district’s groundwater resources and give scope for further research into groundwater exploration in the area.
    Electronic ISSN: 2220-9964
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
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    Ultra-Fast Growth of ZnO Nanorods on Cotton Fabrics and Their Self-Cleaning and Physiological Comfort Properties (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The main aim of the present study was to investigate the effect of microwave irradiation time on the photocatalytic and physiological comfort characteristics of zinc-oxide-nanorod-coated cotton fabrics. An ultra-fast technique was employed to grow the zinc oxide nanorods on cotton fabrics using a microwave-assisted hydrothermal method. The axial (length) and lateral (diameter) growth of the zinc oxide nanorods was observed to increase with microwave irradiation time. The ZnO nanorods uniformly and entirely covered the cotton fibers. The surface morphology, topography and chemical characteristics of the ZnO nanorods were investigated by scanning electron microscopy (SEM), EDS analysis, X-ray diffraction (XRD), atomic force microscopy (AFM) and inductively coupled plasma-optical emission spectrometry (ICP-OES). The degradation of orange II dye under UV light irradiation was observed to assess photocatalytic self-cleaning and solution discoloration ability. The ZnO-nanorod-coated cotton fabrics exhibited excellent photocatalytic activity, as the stains of orange II dye disappeared predominantly within 4 h and the coated fabrics became almost white after 6 h. Analyses of thermal properties, water vapor permeability (WVP), air permeability and stiffness were also performed to investigate the physiological comfort of the ZnO-nanorod-coated fabrics. The thermal conductivity and thermal absorptivity were observed to increase with an increase in the size and density of the ZnO nanorods. Moreover, non-significant reductions in water vapor permeability and air permeability were observed with application of the ZnO nanorods. The stiffness of the ZnO-nanorod-coated cotton fabric increased due to the complete coverage of fibers by the uniform growth of the ZnO nanorods. The ZnO-nanorod-coated cotton fabrics also showed good washing durability and reusability.
    Electronic ISSN: 2079-6412
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
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    Calibration of Low-Cost NO2 Sensors through Environmental Factor Correction (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Low-cost air quality sensors (LCSs) have become more widespread due to their low cost and increased capabilities; however, to supplement more traditional air quality networks, the performance of these LCSs needs to be validated. This study focused on NO2 measurements from eight Clarity Node-S sensors and used various environmental factors to calibrate the LCSs. To validate the calibration performance, we calculated the root-mean-square error (RMSE), mean absolute error (MAE), R2, and slope compared to reference measurements. Raw results from six of these sensors were comparable to those reported for other NO2 LCSs; however, two of the evaluated LCSs had RMSE values ~20 ppb higher than the other six LCSs. By applying a sensor-specific calibration that corrects for relative humidity, temperature, and ozone, this discrepancy was mitigated. In addition, this calibration improved the RMSE, MAE, R2, and slope of all eight LCS compared to the raw data. It should be noted that relatively stable environmental conditions over the course of the LCS deployment period benefited calibration performance over time. These results demonstrate the importance of developing LCS calibration models for individual sensors that consider pertinent environmental factors.
    Electronic ISSN: 2305-6304
    Topics: Chemistry and Pharmacology
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    Soft Is Better: Determinants of Preferences for Non-Motorized Forms of Transportation in Urban Tourism Destinations (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Non-motorized forms of transportation are increasingly perceived as an option that can contribute to reducing the ecological impact of the transportation of tourists while offering satisfactory opportunities to appreciate the urban environment. Walking, bicycles, and other forms of non-motorized transport are increasingly used in urban contexts, both by residents and tourists. By looking into the characteristics and trip motivations of international tourists visiting the city of Barcelona, our analysis identifies the groups of tourists more oriented to these soft forms of mobility and also takes into consideration how they obtained previous information about the destination. Based on an extensive survey conducted in the city, the results of our multinomial logistic regressions reveal a slight generational divide when looking at sources of information (with retired tourists less oriented to digital tools) and a strong generational divide when observing transport choices (younger tourists more oriented to both soft or collective forms of mobility). Our results also show that tourists traveling in groups and/or with trips organized by travel companies and other organizations tend to prefer the utilization of private cars. These results can be used to promote the non-motorized mobility of tourists in other urban destinations.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
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    Affective Saturation Index: A Lexical Measure of Affect (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Affect plays a major role in the individual’s daily life, driving the sensemaking of experience, psychopathological conditions, social representations of phenomena, and ways of coping with others. The characteristics of affect have been traditionally investigated through physiological, self-report, and behavioral measures. The present article proposes a text-based measure to detect affect intensity: the Affective Saturation Index (ASI). The ASI rationale and the conceptualization of affect are overviewed, and an initial validation study on the ASI’s convergent and concurrent validity is presented. Forty individuals completed a non-clinical semi-structured interview. For each interview transcript, the ASI was esteemed and compared to the individual’s physiological index of propensity to affective arousal (measured by heart rate variability (HRV)); transcript semantic complexity (measured through the Semantic Entropy Index (SEI)); and lexical syntactic complexity (measured through the Flesch–Vacca Index (FVI)). ANOVAs and bi-variate correlations estimated the size of the relationships between indexes and sample characteristics (age, gender), then a set of multiple linear regressions tested the ASI’s association with HRV, the SEI, and the FVI. Results support the ASI construct and criteria validity. The ASI proved able to detect affective saturation in interview transcripts (SEI and FVI, adjusted R2 = 0.428 and adjusted R2 = 0.241, respectively) and the way the text’s affective saturation reflected the intensity of the individual’s affective state (HRV, adjusted R2 = 0.428). In conclusion, although the specificity of the sample (psychology students) limits the findings’ generalizability, the ASI provides the chance to use written texts to measure affect in accordance with a dynamic approach, independent of the spatio-temporal setting in which they were produced. In doing so, the ASI provides a way to empower the empirical analysis of fields such as psychotherapy and social group dynamics.
    Electronic ISSN: 1099-4300
    Topics: Chemistry and Pharmacology , Physics
    Published by Molecular Diversity Preservation International
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    Modeling Structure–Activity Relationship of AMPK Activation (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The adenosine monophosphate activated protein kinase (AMPK) is critical in the regulation of important cellular functions such as lipid, glucose, and protein metabolism; mitochondrial biogenesis and autophagy; and cellular growth. In many diseases—such as metabolic syndrome, obesity, diabetes, and also cancer—activation of AMPK is beneficial. Therefore, there is growing interest in AMPK activators that act either by direct action on the enzyme itself or by indirect activation of upstream regulators. Many natural compounds have been described that activate AMPK indirectly. These compounds are usually contained in mixtures with a variety of structurally different other compounds, which in turn can also alter the activity of AMPK via one or more pathways. For these compounds, experiments are complicated, since the required pure substances are often not yet isolated and/or therefore not sufficiently available. Therefore, our goal was to develop a screening tool that could handle the profound heterogeneity in activation pathways of the AMPK. Since machine learning algorithms can model complex (unknown) relationships and patterns, some of these methods (random forest, support vector machines, stochastic gradient boosting, logistic regression, and deep neural network) were applied and validated using a database, comprising of 904 activating and 799 neutral or inhibiting compounds identified by extensive PubMed literature search and PubChem Bioassay database. All models showed unexpectedly high classification accuracy in training, but more importantly in predicting the unseen test data. These models are therefore suitable tools for rapid in silico screening of established substances or multicomponent mixtures and can be used to identify compounds of interest for further testing.
    Electronic ISSN: 1420-3049
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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    Numerical and Experimental Investigation of a Thermoelectric-Based Radiant Ceiling Panel with Phase Change Material for Building Cooling Applications (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The present paper investigates the performance of a thermoelectric (TE)-based radiant ceiling panel with an additional layer of phase change material (PCM) for building cooling application through numerical and experimental analyses. The design of the ceiling panel consisted of an aluminum sheet with TE modules installed on the back to maintain a relatively low ceiling temperature that provided cooling through radiation and convection. A three-dimensional model was developed in COMSOL Multiphysics, and the system’s performance in several different configurations was assessed. The effect of the number of TE modules, as well as incorporating different amounts of PCM under transient conditions, was investigated for two modes of operation: startup and shutdown. It was shown that for a 609.6 mm × 609.6 mm ceiling panel, the use of four TE modules reduced the average surface temperature down to the comfort range in less than 5 min while producing a relatively uniform temperature distribution across the ceiling panel. It was also shown that the addition of a 2 mm thick PCM layer to the back of the ceiling panel enhanced the system’s performance by elongating the time that it took for the ceiling panel’s temperature to exceed the comfort range when the system shut down ,which in turn reduced the number of on/off cycling of the system. The numerical results demonstrated a good agreement with the experimental data. The results from this study can be used for the optimal design of a TE-based radiant ceiling cooling system as a promising technology for smart buildings.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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    A Study of Thermal Degradation and Fire Behaviour of Polymer Composites and Their Gaseous Emission Assessment (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The use of polymer composite materials in the aeronautics and automotive sectors has increased dramatically, and their fire behaviour has become a critical parameter in terms of fire safety. On this premise, it is critical to demonstrate that these composite materials constitute elements whose safety justifies a high level of confidence. This is based on their combustibility and the rate at which flammable and toxic gaseous species are emitted. Thus, strict fire safety regulations are enforced by the relevant authorities concerned because of their potential fire risk. This study analysed papers published between 1970 and 2021 that described the devices used to characterise the thermal behaviour of composite materials at various scales. The objective was to highlight the thermophysical phenomena, making it possible to accurately assess the flammability and thermal stability of polymer composite materials. The results of this research reveal that the small-scale facilities provide detailed understanding and mastery of the thermal reaction properties of the composites. While with the medium scale, the extended fire reaction parameters, which are the key indicators of the fire safety performance, can be determined. On a large scale, the tests were carried out using devices such as the NexGen burner recommended by the FAA. Therefore, with such assays, it is possible to assess the rates of thermal degradation as well as quantified pyrolysis gases. However, compared to other scales, there were very few works on a large scale. In addition, by focusing on the polluting nature of synthetic composite materials, there is also few research studies aimed at designing new polymer composite materials from biological sources.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 43
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    Lactic Acid Bacteria Fermented Cordyceps militaris (GRC-SC11) Suppresses IgE Mediated Mast Cell Activation and Type I Hypersensitive Allergic Murine Model (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Cordyceps militaris (C. militaris) has various biomedical applications in traditional oriental medicine for different diseases including inflammatory and immune-dysregulated diseases. It is a reservoir of nutritional components such as cordycepin, polysaccharides, and antioxidants. To improve its bioactivity, we fermented C. militaris with a Pediococcus pentosaceus strain isolated from a salted small octopus (SC11). The current study aimed to evaluate whether P. pentosaceus (SC11) fermentation could enhance the anti-allergic potential of C. militaris cultured on germinated Rhynchosia nulubilis (GRC) against a type I hypersensitive reaction in in vitro and in vivo studies. Total antioxidant capacity and cordycepin content were significantly increased in GRC after SC11 fermentation. GRC-SC11 showed significantly enhanced anti-allergic responses by inhibiting immunoglobulin E (IgE)/antigen-induced degranulation in RBL-2H3 cells, compared to GRC. The results demonstrated the significant inhibition of phosphorylated spleen tyrosine kinase (Syk)/ p38/GRB2-associated binding protein 2 (Gab2)/c-jun in IgE/Ag-triggered RBL-2H3 cells. Furthermore, suppressed mRNA levels of interleukin-4 (IL-4) and tumor necrosis factor-α (TNF-α) in IgE/Ag-activated RBL-2H3 cells were observed. GRC-SC11 significantly ameliorated IgE-induced allergic reactions by suppressing the ear swelling, vascular permeability, and inflammatory cell infiltration in passive cutaneous anaphylaxis (PCA) BALB/c mice. In conclusion, GRC fermented with P.pentosaceus exerted enhanced anti-allergic effects, and increased the cordycepin content and antioxidants potential compared to GRC. It can be used as bio-functional food in the prevention and management of type I allergic diseases.
    Electronic ISSN: 2072-6643
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Published by Molecular Diversity Preservation International
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    Rapid Detection of Small Faults and Oscillations in Synchronous Generator Systems Using GMDH Neural Networks and High-Gain Observers (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: This paper presents a robust and efficient fault detection and diagnosis framework for handling small faults and oscillations in synchronous generator (SG) systems. The proposed framework utilizes the Brunovsky form representation of nonlinear systems to mathematically formulate the fault detection problem. A differential flatness model of SG systems is provided to meet the conditions of the Brunovsky form representation. A combination of high-gain observer and group method of data handling neural network is employed to estimate the trajectory of the system and to learn/approximate the fault- and uncertainty-associated functions. The fault detection mechanism is developed based on the output residual generation and monitoring so that any unfavorable oscillation and/or fault occurrence can be detected rapidly. Accordingly, an average L1-norm criterion is proposed for rapid decision making in faulty situations. The performance of the proposed framework is investigated for two benchmark scenarios which are actuation fault and fault impact on system dynamics. The simulation results demonstrate the capacity and effectiveness of the proposed solution for rapid fault detection and diagnosis in SG systems in practice, and thus enhancing service maintenance, protection, and life cycle of SGs.
    Electronic ISSN: 2079-9292
    Topics: Electrical Engineering, Measurement and Control Technology
    Published by Molecular Diversity Preservation International
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    Bioprinting Au Natural: The Biologics of Bioinks (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The development of appropriate bioinks is a complex task, dependent on the mechanical and biochemical requirements of the final construct and the type of printer used for fabrication. The two most common tissue printers are micro-extrusion and digital light projection printers. Here we briefly discuss the required characteristics of a bioink for each of these printing processes. However, physical printing is only a short window in the lifespan of a printed construct—the system must support and facilitate cellular development after it is printed. To that end, we provide a broad overview of some of the biological molecules currently used as bioinks. Each molecule has advantages for specific tissues/cells, and potential disadvantages are discussed, along with examples of their current use in the field. Notably, it is stressed that active researchers are trending towards the use of composite bioinks. Utilizing the strengths from multiple materials is highlighted as a key component of bioink development.
    Electronic ISSN: 2218-273X
    Topics: Biology
    Published by Molecular Diversity Preservation International
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    District Heating as Demand Response Aggregator: Estimation of the Flexible Potential in the Italian Peninsula (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The liberalization of the gas market has deeply affected the structure of the gas system. The change from a vertically integrated utility structure to a liberalized architecture has resulted in a new network asset where aggregators could play a key role. To enable aggregators’ functionalities, the gas system has moved to a smart configuration. The development of this Advanced Metering Infrastructure (AMI) allowing a two-way communication between the utility and the consumers, together with demand response programs, prove to be an advantageous solution. Utilities are allowed to manage consumers’ gas load by asking them to reduce or shift their gas usage so that rebates or back payments could be available for consumers. In this framework, aimed at ensuring the feasibility of the gas system and promoting the aggregation of small gas loads, a new agent has been identified. In this research, the potential of district heating systems as gas market aggregators, together with a novel architecture for the gas network system has been identified. Furthermore, DR benefits in natural gas systems have been assessed with a focus on the Italian peninsula, where the authors have already carried out a previous analysis in this regard.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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    Effects of Moringa oleifera Leaf Extracts on Xanthomonas campestris pv. campestris (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Xanthomonas campestris pv. campestris (Xcc) is a Gram-negative bacterium belonging to the Xanthomonodaceae family, causing black rot in crucifers. To control this pathogen, the study investigated the effect of different leaves extracts of Moringa oleifera Lam., a tropical plant, well known for its food properties and with countless applications in many different fields, from nutraceutical (hypoglycemic) to the cosmetic (sunscreen) properties. Nevertheless, several studies pointed to its antibacterial action against both Gram-negative and Gram-positive bacteria. Many bioactive compounds, including flavonoids, phenolic acids, alkaloids, isothiocyanates, tannins and saponins, contained in these extracts, are responsible for its countless activities. The analyses carried out in this study show that the methanolic, hydroalcoholic and hydroalcoholic maltodextrin extracts have both bacteriostatic and bactericidal effects at concentrations of 0.5, 0.5 and 0.1 mg/mL respectively. In particular, the study shows how all extracts can alter membrane permeability, to adversely affect swarming motility, and to alter biofilm formation in Xcc. The in planta experiments showed a reduction of the necrosis area in the infected radishes, although the ability of the extracts to be absorbed by root systems is yet to be understood, in order to reach the target point.
    Electronic ISSN: 2076-2607
    Topics: Biology
    Published by Molecular Diversity Preservation International
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    A Study of the Energy Exchange within a Hybrid Energy Storage System and a Comparison of the Capacities, Lifetimes, and Costs of Different Systems (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: By combining the advantages of different energy storage technologies, the hybrid energy storage system (HESS) can satisfy the multiple requirements of prosumer systems. However, the required capacity of the HESS is larger than that of the single-battery energy storage system (ESS). This paper investigates the energy exchange within the HESS caused by the phase shift of the low-pass filter controller and its relevant impact on the HESS. The results show that unnecessary energy exchange results in an oversized capacity and increased energy loss. In addition, the increase in the time constant of the low-pass filter controller leads to a larger phase shift, further contributing to the increases in the total capacity and energy loss. Furthermore, this paper compares the single-battery ESS, the battery-supercapacitor HESS, and the battery-flywheel HESS implemented in a household-prosumer system along with a renewable energy source (RES). The comparison of the ESS combinations demonstrates the differences between their power flows, the required capacities of their individual energy storage devices (ESDs), their energy losses, their battery lifetimes, and their project costs. The results indicate that techno-economic analysis should be performed carefully to select the appropriate ESS solution for specific household-prosumer systems.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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    Efficient Degradation of Iopromide by Using Sulfite Activated with Mackinawite (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Iopromide (IOP), an iodinated X-ray contrast medium (ICM), is identified as a precursor to iodide disinfection byproducts that have high genotoxicity and cytotoxicity to mammals. ICM remains persistent through typical wastewater treatment processes and even through some hydroxyl radical-based advanced oxidation processes. The development of new technologies to remove ICMs is needed. In this work, mackinawite (FeS)-activated sulfite autoxidation was employed for the degradation of IOP-containing water. The experiment was performed in a 500 mL self-made temperature-controlled reactor with online monitoring pH and dissolved oxygen in the laboratory. The effects of various parameters, such as initial pH values, sulfite dosages, FeS dosages, dissolved oxygen, and inorganic anions on the performance of the treatment process have been investigated. Eighty percent of IOP could be degraded in 15 min with 1 g L−1 FeS, 400 μmol L−1 sulfite at pH 8, and high efficiency on the removal of total organic carbon (TOC) was achieved, which is 71.8% via a reaction for 1 h. The generated hydroxyl and oxysulfur radicals, which contributed to the oxidation process, were identified through radical quenching experiments. The dissolved oxygen was essential for the degradation of IOP. The presence of Cl- could facilitate IOP degradation, while NO3- and CO32- could inhibit the degradation process. The reaction pathway involving H-abstraction and oxidative decarboxylation was proposed, based on product identification. The current system shows good applicability for the degradation of IOP and may help in developing a new approach for the treatment of ICM-containing water.
    Electronic ISSN: 1420-3049
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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    Cross-Amplification in Strigiformes: A New STR Panel for Forensic Purposes (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Strigiformes are affected by a substantial decline mainly caused by habitat loss and destruction, poaching, and trapping. Moreover, the increasing trend in bird trade and the growing interest in wild-caught rather than captive-bred birds are expected to encourage illegal trade. The biomolecular investigation represents a valuable tool to track illegal trade and to explore the genetic variability to preserving biodiversity. Microsatellite loci (STRs) are the most used markers to study genetic variability. Despite the availability of species-specific microsatellite loci in Strigiformes, a unique panel permitting the description of the genetic variability across species has not been identified yet. We tested 32 highly polymorphic microsatellite markers to evaluate the reliability of a unique microsatellite panel in different species of Strigiformes and its use for conservation and forensic purposes. We included in the study 84 individuals belonging to 28 parental groups and 11 species of Strigiformes. After screening polymorphic microsatellite loci, the description of genetic variability, and the kinship assessment, we characterized a final panel of 12 microsatellite loci able to identify individuals in 9 Strigiformes species. This STR panel might support the authorities in the forensic investigation for suspected smugglers and false parental claims; moreover, it can be useful to evaluate relatedness among individuals in captive-bred populations and to implement research projects finalized to the description of the genetic variability in wild populations.
    Electronic ISSN: 2073-4425
    Topics: Biology
    Published by Molecular Diversity Preservation International
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