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  • Male  (1,816)
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  • Chemistry
  • Nature Publishing Group (NPG)  (2,063)
  • Alliance for Coastal Technologies
  • 1
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    Evaluating approaches and technologies for monitoring organic contaminants in the aquatic environment, Ann Arbor, MI, July 21-23, 2006: workshop proceedings (2021)
    Alliance for Coastal Technologies | Solomons, MD
    In:  http://aquaticcommons.org/id/eprint/3114 | 130 | 2011-09-29 17:51:58 | 3114 | University of Maryland Center for Environmental Science. Chesapeake Biological Laboratory
    Details
    Publication Date: 2021-07-01
    Description: The Alliance for Coastal Technologies (ACT) convened a workshop on Evaluating Approaches and Technologies for Monitoring Organic Contaminants in the Aquatic Environment in Ann Arbor, MI on July 21-23, 2006. The primary objectives of this workshop were to: 1) identify the priority management information needs relative to organic contaminant loading; 2) explore themost appropriate approaches to estimating mass loading; and 3) evaluate the current status of thesensor technology. To meet these objectives, a mixture of leading research scientists, resourcemanagers, and industry representatives were brought together for a focused two-day workshop.The workshop featured four plenary talks followed by breakout sessions in which arranged groupsof participants where charged to respond to a series of focused discussion questions.At present, there are major concerns about the inadequacies in approaches and technologies forquantifying mass emissions and detection of organic contaminants for protecting municipal watersupplies and receiving waters. Managers use estimates of land-based contaminant loadings torivers, lakes, and oceans to assess relative risk among various contaminant sources, determinecompliance with regulatory standards, and define progress in source reduction. However, accuratelyquantifying contaminant loading remains a major challenge. Loading occurs over a range ofhydrologic conditions, requiring measurement technologies that can accommodate a broad rangeof ambient conditions. In addition, in situ chemical sensors that provide a means for acquiringcontinuous concentration measurements are still under development, particularly for organic contaminantsthat typically occur at low concentrations. Better approaches and strategies for estimatingcontaminant loading, including evaluations of both sampling design and sensor technologies,need to be identified. The following general recommendations were made in an effort to advancefuture organic contaminant monitoring:1. Improve the understanding of material balance in aquatic systems and the relationship betweenpotential surrogate measures (e.g., DOC, chlorophyll, particle size distribution) and target constituents.2. Develop continuous real-time sensors to be used by managers as screening measures and triggersfor more intensive monitoring.3. Pursue surrogate measures and indicators of organic pollutant contamination, such as CDOM,turbidity, or non-equilibrium partitioning.4. Develop continuous field-deployable sensors for PCBs, PAHs, pyrethroids, and emerging contaminantsof concern and develop strategies that couple sampling approaches with tools that incorporatesensor synergy (i.e., measure appropriate surrogates along with the dissolved organics toallow full mass emission estimation).[PDF contains 20 pages]
    Description: NOAA
    Description: Alliance for Coastal Technologies, CBL/UMCES
    Keywords: Engineering ; Earth Sciences ; Environment ; Chemistry
    Repository Name: AquaDocs
    Type: monograph
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    State of Technology for In Situ Measures of Salinity Using Conductive Temperature Sensors, Savannah, Georgia, December 3-5, 2007: workshop proceedings (2021)
    Alliance for Coastal Technologies | Solomons, MD
    In:  http://aquaticcommons.org/id/eprint/3110 | 130 | 2011-09-29 17:51:42 | 3110 | University of Maryland Center for Environmental Science. Chesapeake Biological Laboratory
    Details
    Publication Date: 2021-07-01
    Description: This Alliance for Coastal Technologies (ACT) workshop was convened to assess the availabilityand state of development of conductivity-temperature sensors that can meet the needs of coastalmonitoring and management communities. Rased on the discussion, there are presently a numberof commercial sensor options available, with a wide range of package configurations suitable fordeployment in a range of coastal environments. However, some of the central questions posedin the workshop planning documents were left somewhat unresolved. The workshop descriptionemphasized coastal management requirements and, in particular, whether less expensive, easilydeployed, lower-resolution instruments might serve many management needs. While several participantsexpressed interest in this class of conductivity-temperature sensors, based on input fromthe manufacturers, it is not clear that simply relaxing the present level of resolution of existing instrumentswill result in instruments of significantly lower unit cost. Conductivity-temperature sensorsare available near or under the $1,000 unit cost that was operationally defined at the workshopas a breakpoint for what might be considered to be a "low cost" sensor. For the manufacturers, akey consideration before undertaking the effort to develop lower cost sensors is whether there willbe a significant market. In terms of defining "low cost," it was also emphasized that the "life cyclecosts" for a given instrument must be considered (e.g., including personnel costs for deploymentand maintenance). An adequate market survey to demonstrate likely applications and a viablemarket for lower cost sensors is needed. Another topic for the workshop was the introductionto the proposed ACT verification for conductivity-temperature sensors. Following a summaryof the process as envisioned by ACT, initial feedback was solicited. Protocol development willbe pursued further in a workshop involving ACT personnel and conductivity-temperature sensormanufacturers.[PDF contains 28 pages]
    Description: NOAA
    Description: Alliance for Coastal Technologies, CBL/UMCES
    Keywords: Earth Sciences ; Environment ; Chemistry
    Repository Name: AquaDocs
    Type: monograph
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  • 3
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    Applications of in situ Fluorometers in Nearshore waters, Cape Elizabeth, Maine, February 2-4,2005: workshop proceedings (2021)
    Alliance for Coastal Technologies | Solomons, MD
    In:  http://aquaticcommons.org/id/eprint/3126 | 130 | 2011-09-29 17:52:50 | 3126
    Details
    Publication Date: 2021-06-25
    Description: The Alliance for Coastal Technologies (ACT) Workshop "Applications of in situ Fluorometers inNearshore Waters" was held in Cape Elizabeth, Maine, February 2-4,2005, with sponsorship bythe Gulf of Maine Ocean Observing System (GoMOOS), one of the ACT partner organization.The purpose of the workshop was to explore recent trends in fluorometry as it relates to resourcemanagement applications in nearshore environments. Participants included representatives fromstate and federal environmental management agencies as well as research institutions, many ofwhom are currently using this technology in their research and management applications.Manufacturers and developers of fluorometric measuring systems also attended the meeting.The Workshop attendees discussed the historical and present uses of fluorometry technology andidentified the great potential for its use by coastal managers to fulfill their regulatory andmanagement objectives. Participants also identified some of the challenges associated with thecorrect use of Fluorometers to estimate biomass and the rate of primary productivity. TheWorkshop concluded that in order to expand the existing use of fluorometers in both academicand resource management disciplines, several issues concerning data collection, instrumentcalibration, and data interpretation needed to be addressed. Participants identified twelverecommendations, the top five of which are listed below:Recommendations1) Develop a "Guide" that describes the most important aspects of fluorescencemeasurements. This guide should be written by an expert party, with both research andindustry input, and should be distributed by all manufacturers with theirinstrumentation. The guide should also be made available on the ACT website as wellas those of other relevant organizations. The guide should include discussions on thefollowing topics:The benefits of using fluorometers in research and resource managementapplications;What fluorometers can and cannot provide in terms of measurements;The necessary assumptions required before applying fluorometry;Characterization and calibration of fluorometers; (pdf contains 32 pages)
    Description: NOAA
    Description: Alliance for Coastal Technologies, CBL/UMCES
    Keywords: Environment ; Chemistry
    Repository Name: AquaDocs
    Type: monograph
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  • 4
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    Sex bias blights drug studies (2010)
    Nature Publishing Group (NPG)
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    Publication Date: 2010-03-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Check Hayden, Erika -- England -- Nature. 2010 Mar 18;464(7287):332-3. doi: 10.1038/464332b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20237530" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bias (Epidemiology) ; Biomedical Research/*methods ; Clinical Trials as Topic/methods ; Drug Evaluation/*methods ; Female ; Humans ; Male ; Patient Selection ; Prejudice ; *Sex Characteristics ; Sex Distribution
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 5
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    The primate connection (2010)
    Nature Publishing Group (NPG)
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    Publication Date: 2010-07-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Trivedi, Bijal -- England -- Nature. 2010 Jul 15;466(7304):S5. doi: 10.1038/nature09236.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20631704" target="_blank"〉PubMed〈/a〉
    Keywords: AIDS Vaccines/immunology ; Animals ; Chronic Disease ; Disease Models, Animal ; Disease Progression ; Female ; Genome, Viral/genetics ; HIV Infections/*immunology/physiopathology/virology ; HIV-1/genetics/growth & development/immunology ; Host-Pathogen Interactions/immunology ; Immunity, Innate/immunology ; Inflammation/immunology/pathology ; Interleukin-17/immunology ; Macaca/immunology/virology ; Male ; Physiology, Comparative/methods ; Primates/*immunology/metabolism/*virology ; Receptors, HIV/metabolism ; Simian Acquired Immunodeficiency Syndrome/*immunology/metabolism/virology ; Simian Immunodeficiency Virus/classification/genetics/pathogenicity/*physiology ; T-Lymphocytes, Helper-Inducer/immunology/pathology ; Viral Load
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
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    Males still dominate animal studies (2010)
    Nature Publishing Group (NPG)
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    Publication Date: 2010-06-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zucker, Irving -- Beery, Annaliese K -- England -- Nature. 2010 Jun 10;465(7299):690. doi: 10.1038/465690a.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departmentsof Psychology, Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720, USA. irvzuck@berkeley.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20535186" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bias (Epidemiology) ; Biomedical Research/ethics/*methods/trends ; *Disease Models, Animal ; Female ; Humans ; Male ; Prevalence ; *Sex Characteristics ; Sex Distribution ; Sex Factors
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 7
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    Foot strike patterns and collision forces in habitually barefoot versus shod runners (2010)
    Nature Publishing Group (NPG)
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    Publication Date: 2010-01-30
    Description: Humans have engaged in endurance running for millions of years, but the modern running shoe was not invented until the 1970s. For most of human evolutionary history, runners were either barefoot or wore minimal footwear such as sandals or moccasins with smaller heels and little cushioning relative to modern running shoes. We wondered how runners coped with the impact caused by the foot colliding with the ground before the invention of the modern shoe. Here we show that habitually barefoot endurance runners often land on the fore-foot (fore-foot strike) before bringing down the heel, but they sometimes land with a flat foot (mid-foot strike) or, less often, on the heel (rear-foot strike). In contrast, habitually shod runners mostly rear-foot strike, facilitated by the elevated and cushioned heel of the modern running shoe. Kinematic and kinetic analyses show that even on hard surfaces, barefoot runners who fore-foot strike generate smaller collision forces than shod rear-foot strikers. This difference results primarily from a more plantarflexed foot at landing and more ankle compliance during impact, decreasing the effective mass of the body that collides with the ground. Fore-foot- and mid-foot-strike gaits were probably more common when humans ran barefoot or in minimal shoes, and may protect the feet and lower limbs from some of the impact-related injuries now experienced by a high percentage of runners.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lieberman, Daniel E -- Venkadesan, Madhusudhan -- Werbel, William A -- Daoud, Adam I -- D'Andrea, Susan -- Davis, Irene S -- Mang'eni, Robert Ojiambo -- Pitsiladis, Yannis -- England -- Nature. 2010 Jan 28;463(7280):531-5. doi: 10.1038/nature08723.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Human Evolutionary Biology, 11 Divinity Avenue, Harvard University, Cambridge, Massachusetts 02138, USA. danlieb@fas.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20111000" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Biomechanical Phenomena ; Child ; Female ; Foot/*physiology ; Forefoot, Human/physiology ; Gait/physiology ; Humans ; Kenya ; Male ; Running/*physiology ; *Shoes/standards ; *Stress, Mechanical ; United States ; Weight-Bearing/physiology ; Young Adult
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 8
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    Amygdalar and hippocampal substrates of anxious temperament differ in their heritability (2010)
    Nature Publishing Group (NPG)
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    Publication Date: 2010-08-13
    Description: Anxious temperament (AT) in human and non-human primates is a trait-like phenotype evident early in life that is characterized by increased behavioural and physiological reactivity to mildly threatening stimuli. Studies in children demonstrate that AT is an important risk factor for the later development of anxiety disorders, depression and comorbid substance abuse. Despite its importance as an early predictor of psychopathology, little is known about the factors that predispose vulnerable children to develop AT and the brain systems that underlie its expression. To characterize the neural circuitry associated with AT and the extent to which the function of this circuit is heritable, we studied a large sample of rhesus monkeys phenotyped for AT. Using 238 young monkeys from a multigenerational single-family pedigree, we simultaneously assessed brain metabolic activity and AT while monkeys were exposed to the relevant ethological condition that elicits the phenotype. High-resolution (18)F-labelled deoxyglucose positron-emission tomography (FDG-PET) was selected as the imaging modality because it provides semi-quantitative indices of absolute glucose metabolic rate, allows for simultaneous measurement of behaviour and brain activity, and has a time course suited for assessing temperament-associated sustained brain responses. Here we demonstrate that the central nucleus region of the amygdala and the anterior hippocampus are key components of the neural circuit predictive of AT. We also show significant heritability of the AT phenotype by using quantitative genetic analysis. Additionally, using voxelwise analyses, we reveal significant heritability of metabolic activity in AT-associated hippocampal regions. However, activity in the amygdala region predictive of AT is not significantly heritable. Furthermore, the heritabilities of the hippocampal and amygdala regions significantly differ from each other. Even though these structures are closely linked, the results suggest differential influences of genes and environment on how these brain regions mediate AT and the ongoing risk of developing anxiety and depression.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998538/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998538/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Oler, Jonathan A -- Fox, Andrew S -- Shelton, Steven E -- Rogers, Jeffrey -- Dyer, Thomas D -- Davidson, Richard J -- Shelledy, Wendy -- Oakes, Terrence R -- Blangero, John -- Kalin, Ned H -- MH018931/MH/NIMH NIH HHS/ -- MH046729/MH/NIMH NIH HHS/ -- MH059490/MH/NIMH NIH HHS/ -- MH081884/MH/NIMH NIH HHS/ -- MH084051/MH/NIMH NIH HHS/ -- P50 MH084051/MH/NIMH NIH HHS/ -- P50 MH084051-030001/MH/NIMH NIH HHS/ -- R01 MH046729/MH/NIMH NIH HHS/ -- R01 MH046729-17/MH/NIMH NIH HHS/ -- R01 MH081884/MH/NIMH NIH HHS/ -- R01 MH081884-04/MH/NIMH NIH HHS/ -- R37 MH059490/MH/NIMH NIH HHS/ -- R37 MH059490-13/MH/NIMH NIH HHS/ -- England -- Nature. 2010 Aug 12;466(7308):864-8. doi: 10.1038/nature09282.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychiatry, University of Wisconsin-Madison, Madison, Wisconsin 53719, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20703306" target="_blank"〉PubMed〈/a〉
    Keywords: Amygdala/*metabolism ; Animals ; Anxiety/*genetics/*physiopathology ; Depression/genetics ; Female ; Freezing Reaction, Cataleptic ; Genetic Predisposition to Disease/*genetics ; Glucose/metabolism ; *Heredity ; Hippocampus/*metabolism ; Macaca mulatta/genetics/physiology ; Male ; Models, Animal ; Neural Pathways/physiology ; Pedigree ; Phenotype ; Positron-Emission Tomography ; Stress, Psychological ; Temperament/*physiology ; Temporal Lobe/metabolism ; Vocalization, Animal
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 9
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    Forgotten lessons (2010)
    Nature Publishing Group (NPG)
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    Publication Date: 2010-07-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Basu, Paroma -- England -- Nature. 2010 Jul 15;466(7304):S14-5. doi: 10.1038/nature09241.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20631697" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/drug therapy/epidemiology/prevention & ; control/psychology/transmission ; Adult ; Child ; Chronic Disease/drug therapy/epidemiology/prevention & control/psychology ; Community-Institutional Relations ; Developed Countries/*statistics & numerical data ; Female ; HIV Infections/drug therapy/*epidemiology/prevention & ; control/*psychology/transmission ; Health Education ; Humans ; Incidence ; Male ; Patient Compliance/psychology/statistics & numerical data ; Risk-Taking ; Safe Sex/*psychology/*statistics & numerical data ; Viral Load/drug effects
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 10
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    Competition drives cooperation among closely related sperm of deer mice (2010)
    Nature Publishing Group (NPG)
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    Publication Date: 2010-01-22
    Description: Among the extraordinary adaptations driven by sperm competition is the cooperative behaviour of spermatozoa. By forming cooperative groups, sperm can increase their swimming velocity and thereby gain an advantage in intermale sperm competition. Accordingly, selection should favour cooperation of the most closely related sperm to maximize fitness. Here we show that sperm of deer mice (genus Peromyscus) form motile aggregations, then we use this system to test predictions of sperm cooperation. We find that sperm aggregate more often with conspecific than heterospecific sperm, suggesting that individual sperm can discriminate on the basis of genetic relatedness. Next, we provide evidence that the cooperative behaviour of closely related sperm is driven by sperm competition. In a monogamous species lacking sperm competition, Peromyscus polionotus, sperm indiscriminately group with unrelated conspecific sperm. In contrast, in the highly promiscuous deer mouse, Peromyscus maniculatus, sperm are significantly more likely to aggregate with those obtained from the same male than with sperm from an unrelated conspecific donor. Even when we test sperm from sibling males, we continue to see preferential aggregations of related sperm in P. maniculatus. These results suggest that sperm from promiscuous deer mice discriminate among relatives and thereby cooperate with the most closely related sperm, an adaptation likely to have been driven by sperm competition.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824558/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824558/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fisher, Heidi S -- Hoekstra, Hopi E -- F32 GM084719/GM/NIGMS NIH HHS/ -- F32 GM084719-02/GM/NIGMS NIH HHS/ -- England -- Nature. 2010 Feb 11;463(7282):801-3. doi: 10.1038/nature08736. Epub 2010 Jan 20.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Cambridge, Massachusetts 02138, USA. hfisher@oeb.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20090679" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Aggregation ; Competitive Behavior/*physiology ; *Cooperative Behavior ; Copulation/physiology ; Female ; Male ; Peromyscus/*classification/*physiology ; Sexual Behavior, Animal/*physiology ; Species Specificity ; Sperm Motility/physiology ; Spermatozoa/*physiology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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