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  • Springer  (10,415)
  • American Institute of Physics (AIP)
  • American Chemical Society (ACS)
  • 1945-1949  (10,415)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of mathematical biology 11 (1949), S. 59-82 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract A theory of linkage of autopolyploids is developed under consideration ofm loci andr alleles. The simplifying assumption of chromosome segregation, which may be considered as an approximation to the more adequate theory of chromatid segregation, is made throughout. Random mating and distinct, non-overlapping generations are assumed. Under these assumptions the problem is determined by three basic probability distributions—the distributions of genotypes and of gametes, and the segregation distribution. The segregation distribution is assumed to be the same for males and for females. The aim of the paper is to establish recurrence formulas (which allow to find the distributions of gametes and of genotypes from generation to generation, if the distribution of genotypes for an initial generation is known) and to investigate the limit behavior of these distributions as the number of generations increases indefinitely. In the present paper (hereafter referred to as I) the problem is explained, and the three characteristic distributions are introduced for the general case of a 2s-ploid,m loci, andr alleles. Recurrence relations are established for tetraploids,s=2 andm=2 loci, while the recurrence relations for the general case as well as the limit theorems will be given in the second part of this paper (hereafter referred to as II).
    Type of Medium: Electronic Resource
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  • 2
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    Springer
    Bulletin of mathematical biology 11 (1949), S. 83-95 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Steady state kinetic relations previously developed forclosed, homogeneous systems are extended toopen systems consisting of geometrically confined regions of arbitrary shape. The generalized system of consecutive reactions is considered to occur within the cell, and the cell plus environment are treated as an open system. The diffusion condition is imposed upon the kinetic solution for various special cases and the method ofgeneral solution when all products, reactants and intermediates, may enter and leave the cell is indicated.
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  • 3
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    Springer
    Bulletin of mathematical biology 11 (1949), S. 97-103 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract When two polished metal spheres in contact with each other are immersed in a corrosive solution, their surfaces gradually corrode, leaving, however, a non-corroded zone around the point of contact. The size of this zone is a function of the size of the spheres, concentration of the corrosive, and of the time. The phenomenon has been first observed by F. C. Besic on human teeth immersed in hydrochloric acid, and studied on metal balls. In the present paper it is shown that such a phenomenon may be due to gradients of concentration of the corrosive in the neighborhood of the point of contact, caused by the chemical reaction which consumes the corrosive. Approximate expressions for the size of the uncorroded zones as a function of the size of the balls and as a function of time are derived and found to be in fair agreement with F. C. Besic's data.
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  • 4
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    Springer
    Bulletin of mathematical biology 11 (1949), S. 105-113 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract When an individual grows up in a society, he learns certain behavior patterns which are “accepted” by that society. He may in general have a tendency toward behavior patterns other than those which are “accepted” by the society. This tendency toward such unaccepted behavior may be due to a process of cerebration which results in doubt as to the “correctness” of the accepted behavior. Thus, on the one hand, the individual learns to follow the accepted rules almost automatically; on the other hand, he may tend to consciously break those rules. Using a neural circuit, suggested by H. D. Landahl in his theory of learning, a neurobiophysical interpretation of the above situation is outlined. Mathematical expressions are derived which describe the social behavior of an individual as a function of his age, social status, and some neurobiophysical parameters.
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  • 5
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    Springer
    Bulletin of mathematical biology 11 (1949), S. 139-144 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Analysis is made to show that the mitotic index is simply proportional to the ratio of the duration of mitosis (T) to the intermitotic time only under special conditions. In the case of exponential growth of cell population the simple proportionality hold if the product ofT and the growth constant is small. For power law (t n ) growth of cell population the simple proportionality holds only when a steady state of growth has existed for at least ten intermitotic periods. The simple proportionality does not apply in conditions of transient growth.
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  • 6
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    Springer
    Bulletin of mathematical biology 11 (1949), S. 115-138 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Food and metabolic waste products, insofar as they act upon the hereditary substrate of cells, are the most important factors governing tissue growth. Equations describing the growth of tissues are derived in consideration of this fact. A quantity is found in these equations which, if slightly changed, results in very great changes in the growth rate of the tissue, where such very great changes are interpretable as neoplastic growth. The relationship between our equations and similar equations which others have proposed is discussed.
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  • 7
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    Springer
    Bulletin of mathematical biology 11 (1949), S. 145-147 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
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  • 8
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    Springer
    Monatshefte für Mathematik 52 (1948), S. 1-12 
    ISSN: 1436-5081
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
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  • 9
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    Monatshefte für Mathematik 52 (1948), S. 13-37 
    ISSN: 1436-5081
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
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  • 10
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    Springer
    Monatshefte für Mathematik 52 (1948), S. 55-85 
    ISSN: 1436-5081
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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