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  • Molecular Diversity Preservation International  (221,634)
  • 2020-2022  (221,634)
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  • 1
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    A Novel Approach for the Design of Fast-Settling Amplifiers for Biosignal Detection (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The most common method used to pick up biomedical signals is through metallic electrodes coupled to the input of high-gain, low-noise amplifiers. Unfortunately, electrodes, amongst other effects, introduce an undesired contact resistance and a contact potential. The contact potential needs to be rejected since it would otherwise cause the saturation of the input stage of the amplifiers, and this is almost always obtained by inserting a simple RC high-pass filter in the input signal path. The contact resistance needs to be estimated to ensure that it does not impair correct measurements. Methods exist for estimating the contact resistance by dynamically modifying the input network configuration, but because of the presence of the input RC filter, long transients are induced any time a switch occurs between different input configurations, so that the measurement time may become unacceptably long. In this paper, we propose a new topology for a DC removal network at the input of the differential signal amplifier that results in an AC filter whose time constant can be continuously changed by means of a control voltage. As such, we can speed up the recovery from transients by setting very short time constants (during the input resistance estimation process) while maintaining the ability to obtain very low cut-in frequencies by setting a much larger time constant during actual measurements. A prototype of the system was built and tested in order to demonstrate the advantage of the approach we propose in terms of reduced measurement time.
    Electronic ISSN: 2079-9292
    Topics: Electrical Engineering, Measurement and Control Technology
    Published by Molecular Diversity Preservation International
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  • 2
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    Labeling of Installed Heating Appliances in Residential Buildings: An Energy Labeling Methodology for Improving Consumers’ Awareness (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: In the EU 28, the installed heating appliance stock is quite old, with an actual replacement rate of 4%. This is directly reflected in the average efficiency of the installed heating systems, where around 60% of the stock is rated with an energy class of C or D (the lowest classes of the energy label scale). The European project HARP aims at raising consumers’ awareness of the planned replacement of their old and inefficient heating appliances with more efficient and renewable solutions. In this direction, an energy labeling methodology for old appliances has been developed to rate the installed stock before the introduction of the EU energy label. The methodology has been developed for space heating appliances and water heaters, targeting two types of users: end consumers and professional users. The validation considered about 4600 space heating appliances and 800 water heaters built between 1972 and 2019. Three heating appliances and two water heaters were tested in the laboratory, confirming the reliability of the proposed methodology. The expected impact of defining an energy labeling methodology for installed heating appliances increases the current replacement rate of these appliances in the EU from 4% to 5%.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 3
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    A Comprehensive Harmonic Analysis of Current-Mode Power Amplifiers (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: This work presents a comprehensive theoretical analysis of current-mode power amplifiers as a function of input power for different biasing classes under the common simplifying assumption of constant transconductance and hard current cut-off/saturation. Typically, the theoretical analysis of power amplifier performance and behavior are carried out only at maximum output power. However, to achieve high data-rates, modern telecommunication systems adopt signals characterized by a very high peak-to-average power ratio, thus it is useful to analyze the power amplifier behavior as a function of power back-off. Moreover, in many cases, to enhance the efficiency and/or to apply harmonic shaping techniques, a clipped drain-source current, which approaches a square wave, is required. The classical analysis can be extended to low power levels only under the assumption of power-independent conduction angle, which is true only for class-A and class-B amplifiers, and does not take into account possible waveform clipping at maximum current. This work presents a complete theoretical Fourier analysis of FET-based power amplifiers as a function of quiescent drain-source current at any input power level and accounting for the clipped current case, up to the square-wave limit, reorganizing and completing the material that can be found in classical textbooks in the field.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 4
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    Increased Post-Hypoxic Oxidative Stress and Activation of the PERK Branch of the UPR in Trap1-Deficient Drosophila melanogaster Is Abrogated by Metformin (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Hypoxia is known to impair mitochondrial and endoplasmic reticulum (ER) homeostasis. Post-hypoxic perturbations of the ER proteostasis result in the accumulation of misfolded/unfolded proteins leading to the activation of the Unfolded Protein Response (UPR). Mitochondrial chaperone TNF receptor-associated protein 1 (TRAP1) is reported to preserve mitochondrial membrane potential and to impede reactive oxygen species (ROS) production thereby protecting cells from ER stress as well as oxidative stress. The first-line antidiabetic drug Metformin has been attributed a neuroprotective role after hypoxia. Interestingly, Metformin has been reported to rescue mitochondrial deficits in fibroblasts derived from a patient carrying a homozygous TRAP1 loss-of-function mutation. We sought to investigate a putative link between Metformin, TRAP1, and the UPR after hypoxia. We assessed post-hypoxic/reperfusion longevity, mortality, negative geotaxis, ROS production, metabolic activity, gene expression of antioxidant proteins, and activation of the UPR in Trap1-deficient flies. Following hypoxia, Trap1 deficiency caused higher mortality and greater impairments in negative geotaxis compared to controls. Similarly, post-hypoxic production of ROS and UPR activation was significantly higher in Trap1-deficient compared to control flies. Metformin counteracted the deleterious effects of hypoxia in Trap1-deficient flies but had no protective effect in wild-type flies. We provide evidence that TRAP1 is crucially involved in the post-hypoxic regulation of mitochondrial/ER stress and the activation of the UPR. Metformin appears to rescue Trap1-deficiency after hypoxia mitigating ROS production and downregulating the pro-apoptotic PERK (protein kinase R-like ER kinase) arm of the UPR.
    Print ISSN: 1661-6596
    Electronic ISSN: 1422-0067
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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  • 5
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    Identification of Reference Genes for Expression Studies in the Whole-Blood from Three Cattle Breeds under Two States of Livestock Weather Safety (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Real-time PCR is widely used to study the relative abundance of mRNA due to its specificity, sensitivity, and repeatability quantification. However, relative quantification requires a reference gene, which should be stable in its expression, showing lower variation by experimental conditions or tissues. The aim of this study was to evaluate the stability of the expression of five commonly used reference genes (actb, ywhaz, b2m, sdha, and 18s rRNA) at different physiological stages (alert and emergency) in three different cattle breeds. In this study, five genes (actb, ywhaz, b2m, sdha, and 18s rRNA) were selected as candidate reference genes for expression studies in the whole blood from three cattle breeds (Romosinuano, Gyr, and Brahman) under heat stress conditions. The transcription stability of the candidate reference genes was evaluated using geNorm and NormFinder. The results showed that actb, 18SrRNA, and b2m expression were the most stable reference genes for whole blood of Gyr and Brahman breeds under two states of livestock weather safety (alert and emergency). Meanwhile, actb, b2m, and ywhaz were the most stable reference genes for the Romosinuano breed.
    Electronic ISSN: 2076-2615
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Molecular Diversity Preservation International
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  • 6
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    Poor Ventilation Habits in Nursing Homes Have Favoured a High Number of COVID-19 Infections (2021)
    Molecular Diversity Preservation International
    Details
    Publication Date: 2021-10-28
    Description: Residents of nursing homes have been significantly affected by COVID-19 in Spain. The factors that have contributed to the vulnerability of this population are very diverse. In this study, physical agents, chemical pollutants, population density and different capacities of residences were analysed to understand their influence on the number of elderly people who have died in geriatric centres in different autonomous communities (AACCs) of Spain. A statistical analysis was carried out on the variables observed. The results show that many residences with a larger number of deaths were private, with some exceptions. Physical agents and pollutants were found to be determining factors, especially for the communities of Extremadura and Castilla–La Mancha, although the large number of factors involved makes this study complicated. The compromise between air quality and energy efficiency is of great importance, especially when human health is at stake.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 7
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    Energy Self-Sufficient Livestock Farm as the Example of Agricultural Hybrid Off-Grid System (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: Contemporary agriculture has become very energy-intensive and mainly uses electricity, which is needed for technological processes on livestock farms. Livestock faeces are burdensome for the environment due to the release of methane into the atmosphere. This article presents the concept of a self-sufficient livestock farm as an off-grid energy circuit that is a part of the agricultural process. The key idea is to obtain an energy flow using the concept of a smart valve to achieve a self-sufficient energy process based on a biogas plant, renewable energy sources, and energy storage. During the production process, a livestock farm produces large amounts of waste in the form of grey and black manure. On the one hand, these products are highly harmful to the environment, but on the other, they are valuable input products for another process, i.e., methane production. The methane becomes the fuel for cogeneration generators that produce heat and electricity. Heat and electricity are partly returned to the main farming process and partly used by residents of the area. In this way, a livestock farm and the inhabitants of a village or town can become energy self-sufficient and independent of national grids. The idea described in this paper shows the process of energy production combining a biogas plant, renewable energy sources, and an energy storage unit that enable farmland to become fully self-sufficient through the energy flow between all constituents of the energy cycle being maintained by a smart valve.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 8
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    SCADA Data-Based Working Condition Classification for Condition Assessment of Wind Turbine Main Transmission System (2021)
    Molecular Diversity Preservation International
    Details
    Publication Date: 2021-10-28
    Description: Due to the complex and variable conditions under which wind turbines operate, existing working condition classification methods are inadequate for condition assessment of the main transmission system. Because working conditions are too few after classification, it cannot effectively describe the complex and variable working conditions of wind turbine. This can lead to high false-alarm rates in the condition monitoring, which affect normal operations. This paper proposes a working condition classification method for the main transmission system of wind turbines based on supervisory control and data acquisition (SCADA) data. Firstly, correlation analysis of SCADA data acquired by wind farm is used to select the parameters relevant to the main transmission system. Secondly, according to the wind turbine control principle, the working conditions are initially divided into four phases: shutdown, start-up, maximum wind energy tracking, and constant speed. The k-means clustering algorithm is used to subdivide the maximum wind energy-tracking phase and constant speed phase, which account for a larger proportion of the working conditions, to achieve better classification. Finally, a case study is used to demonstrate the calculation of alarm thresholds and alarm rates for each working condition. The results are compared with the direct use of k-means clustering for working condition classification. It is concluded that the proposed method can significantly reduce the false-alarm rate of the vibration detection process.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 9
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    Land Use Change and Its Impact on Landscape Ecological Risk in Typical Areas of the Yellow River Basin in China (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-10-28
    Description: The basic premise of regional ecological construction would be to scientifically and effectively grasp the characteristics of land use change and its impact on landscape ecological risk. The research objects of this paper are the typical areas of the Yellow River Basin in China and “process-change-drive” as the logical main line. Moreover, this paper is based on multi-period land use remote sensing data from 2000 to 2020, the regional land use change process and influencing factors are identified, the temporal and spatial evolution and response process of landscape ecological risk are discussed, and the land use zoning control strategy to reduce ecological risk is put forward. The results indicated: (1) The scale and structure of land use show the characteristics of “many-to-one” and “one-to-many”; (2) the process of land use change is affected by the alternation of multiple factors. The natural environment and socio-economic factors dominate in the early stage and the location and policy factors have a significant impact in the later stage; (3) the overall landscape ecological risk level and conversion rate show a trend of “high in the southeast, low in the northwest”, shift from low to high and landscape ecological risks gradually increase; and (4) in order to improve the regional ecological safety and according to the characteristics of landscape ecological risk and spatial heterogeneity, we should adopt the management and control zoning method and set different levels of control intensity (from key intensity to strict intensity to general intensity), and develop differentiated land use control strategies.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by Molecular Diversity Preservation International
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  • 10
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    Ambient Air Quality Measurement with Low-Cost Optical and Electrochemical Sensors: An Evaluation of Continuous Year-Long Operation (2021)
    Molecular Diversity Preservation International
    Details
    Publication Date: 2021-10-27
    Description: Sensor technology is attractive to the public due to its availability and ease of use. However, its usage raises numerous questions. The general trustworthiness of sensor data is widely discussed, especially with regard to accuracy, precision, and long-term signal stability. The VSB-Technical University of Ostrava has operated an air quality sensor network for more than two years, and its large sets of valid results can help in understanding the limitations of sensory measurement. Monitoring is focused on the concentrations of dust particles, NO2, and ozone to verify the impact of newly planted greenery on the reduction in air pollution. The sensor network currently covers an open field on the outskirts of Ostrava, between Liberty Ironworks and the nearby ISKO1650 monitoring station, where some of the worst air pollution levels in the Czech Republic are regularly measured. In the future, trees should be allowed to grow over the sensors, enabling assessment of the green barrier effect on air pollution. As expected, the service life of the sensors varies from 1 to 3 years; therefore, checks are necessary both prior to the measurement and regularly during operation, verifying output stability and overall performance. Results of the PMx sensory measurements correlated well with the reference method. Concentration values measured by NO2 sensors correlated poorly with the reference method, although timeline plots of concentration changes were in accordance. We suggest that a comparison of timelines should be used for air quality evaluations, rather than particular values. The results showed that the sensor measurements are not yet suitable to replace the reference methods, and dense sensor networks proved useful and robust tools for indicative air quality measurements (AQM).
    Electronic ISSN: 2076-3298
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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