ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The temperature-dependent conformations of poly(U) in 0.5M CsC1 have been studied by carbon-13 nuclear magnetic resonance. The transition from random coil to an ordered structure results in broadening of lines in the 13C spectra, due to intramolecular 1H-13C dipolar interactions and restricted motions in the ordered state. Changes in the chemical shifts suggest that the bases are interacting below the transition temperature. The random coil form shows conformation preferences for internal rotation about C4′-C5′, C5′-O5′, and C3′-O 3′ bonds. The statistical randomness of the coil arises mainly because of flexibility about O-P bonds. The results are analyzed in conjunction with theoretical calculations and light-scattering data.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.1973.360121111
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