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  • Rat  (115)
  • stability
  • Springer  (126)
  • 1975-1979  (126)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 22 (1977), S. 77-84 
    ISSN: 1432-0827
    Keywords: Fluoride ; Blood plasma ; Enamel mineralization ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract It is postulated that tissue fluid F concentrations are the primary determinants of fluoride effects on bones and developing teeth and that these concentrations are dependent on, or mirrored by, blood plasma F. It has earlier been shown that the plasma F levels are dependent on the dietary F supply as well as on skeletal F concentration. Fasting and post-ingestion or postinjection plasma F levels have been determined in rats on F doses that cause different degrees of enamel fluorosis. The results indicate that temporary peak values rather than elevated fasting values are responsible for the occurrence of enamel fluorosis and that the peak values must approach about 10 μM in order to block enamel formation by the ameloblasts. The diagnostic and prognostic importance of plasma F determinations is discussed.
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  • 2
    Electronic Resource
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    Springer
    Calcified tissue international 25 (1978), S. 75-83 
    ISSN: 1432-0827
    Keywords: Rat ; Fluorosis ; Enamel ; Scanning electron microscopy ; Low temperature incineration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Sixteen 58-day-old male rats of Wistar strain, with a mean body weight of 179 g, were divided into two equal groups. Each group of eight animals was maintained for 70 days on drinking water, ad lib., containing no fluorine (control group) and 100 ppm of fluorine (experimental group). All specimens examined were obtained from the incisal portions of the incisors. The following types of enamel specimens were prepared for scanning electron microscopy: (1) acid-etched specimens; (2) acid-etched specimens followed by low temperature microincineration; and (3) fractured specimens. The enamel formed during high fluoride exposure showed marked hypocalcification, that is, the crystallite density in the prism core and interprismatic region was lower than that of control animals. The organic substances appeared to increase in these regions. These changes were prominent in the outer and middle enamel layers. Such changes following fluoride administration appear to indicate an inhibition of enamel maturation, that is, an inhibition of the mineral deposition and/or an inhibition of organic matrix withdrawal.
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  • 3
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    Springer
    Calcified tissue international 23 (1977), S. 161-170 
    ISSN: 1432-0827
    Keywords: Bone ; Growth ; Rat ; Remodeling ; Tetracyclines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Cortical bone remodeling along the femur diaphysis was determined in normal female rats (Sprague-Dawley) with the tetracycline technique. Three segments on the cortical bone circumference (the anterolateral, the medial, and the posterior) were found to be most suitable for the study of the remodeling process. Oxytetracycline was administered at age 60 and 75 days, and groups of animals were killed at age 75, 85, 95, and 105 days. The accumulated endosteal growth during age 60 to 75 days in the anterolateral segment was found to increase uniformly in the distal direction along the femur diaphysis. A method is described where this accumulated endosteal growth is used. This method eliminates the use of calipers to determine the section level and makes it possible to study comparable sections even after varying periods of time. The proximal part of the diaphysis showed periosteal apposition in all three segments. The periosteal apposition turned into resorption in the distal part of the diaphysis in the anterolateral and medial segments, whereas the periosteal appsition increased in the posterior segment. The endosteal growth increased in the distal direction in the anterolateral and medial segments. Irregular OTC bands made measurements of endosteal remodeling in the posterior segment impossible. The cortical width decreased in the distal direction along the femoral shaft. Comparison between the different age groups is described and also the relation between the accumulated endosteal growth and the diameter of the medullary cavity.
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  • 4
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    Springer
    Calcified tissue international 27 (1979), S. 161-164 
    ISSN: 1432-0827
    Keywords: Osteoporosis ; Ovary ; Rat ; Vitamin D
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Fifty adult female rats were used to study the effect of 1-alpha-hydroxyvitamin D3 (1α-OH-D3)on bone after oophorectomy. The experimental period was 6 months. At the end of the experiment the femurs and the tibias were investigated for bone mass and composition. Significant signs of osteopenia occurred as a result of oophorectomy. The treatment with 1α-OH-D3 induced only minor changes in blood chemistry but increased bone mass significantly. The findings support the view that 1α-OH-D3 may be a valuable tool in the treatment of osteoporosis resulting from ovarian insufficiency.
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  • 5
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    Springer
    Journal of statistical physics 15 (1976), S. 477-483 
    ISSN: 1572-9613
    Keywords: Stochastic process ; chemical fluctuations ; Lotka-Volterra model ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Spontaneous fluctuations in the Lotka-Volterra model of chemical reactions are known to grow in an unbounded way when species held in excess are neglected. This result is obtained in a simple way using generalized fluctuation-dissipation principles but appears to be an artifact of ignoring fluctuations in the variables that are held fixed. When fluctuations in the other concentrations are included in the model, the spontaneous fluctuations become bounded.
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  • 6
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    Mycopathologia 55 (1975), S. 53-55 
    ISSN: 1573-0832
    Keywords: Rubratoxine B ; Mitochondria ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The in vitro effect of rubratoxin B on the electron transport system of rat liver mitochondria was investigated. This mycotoxin depressed oxygen consumption in ADP-lacking mitochondria and in ADP-coupled mitochondria, using succinate or β-hydroxybutyrate as substrats. Rubratoxin B is neither an oxidative-phosphorylation inhibitor nor uncoupling agent. Its effect is compared with aflatoxin B1.
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  • 7
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    BIT 17 (1977), S. 321-328 
    ISSN: 1572-9125
    Keywords: 5.15 ; nonlinear equation ; root finding ; multiple root ; secant method ; Steffensen procedure ; order of convergence ; efficiency ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract A superlinear procedure for finding a multiple root is presented. In it the secant method is applied to the given function divided by a divided difference whose increment shrinks toward zero as the root is approached. Two function evaluations per step are required, but no derivatives need be calculated.
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  • 8
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    Journal of statistical physics 13 (1975), S. 1-16 
    ISSN: 1572-9613
    Keywords: Electrical circuit ; entropy production ; stability ; bistability ; fluctuations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A number of the theorems expounded by Prigogine, Glansdorff and their collaborators are translated into electrical circuit terminology and their validity and significance discussed. The simultaneous occurrence of inductors and capacitors represents a situation not envisioned in the chemically oriented discussions and imposes some limitations. The electrical terminology also leads to “dual” theorems, in which voltage sources are replaced by current sources. The validity of the theorems in situations in which fluctuations are critical to the relaxation behavior is analyzed. The “excess entropy production” theorem is only valid if the circuit relaxation can be described by single-valued macroscopic variables, but not if it must be described by distribution functions. We stress that no purely local characterization, which examines a multistable system only in the neighborhoods where it occurs with high probability, can predict or characterize the steady state.
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  • 9
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    Journal of statistical physics 14 (1976), S. 399-416 
    ISSN: 1572-9613
    Keywords: Reservoir-driven open systems ; coherent states ; entropy production ; nonlinear equations ; irreversible processes ; stationary state ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A kinetic equation for the density matrix of a monomode laser with explicit coupling with a thermal reservoir representing the cavity and a nonthermal one representing the pumping mechanism is derived. The macroscopic behavior of this system, inferred from Glauber's P function, is discussed within the framework of Glansdorff-Prigogine's theory of far-from-thermal-equilibrium open systems.
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  • 10
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    Journal of statistical physics 18 (1978), S. 585-632 
    ISSN: 1572-9613
    Keywords: Strong coupling BCS model ; macroscopic states ; heat bath ; dissipative semigroup ; bifurcation ; Liapunov function ; stability ; nonequilibrium thermodynamics ; fluctuations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The dynamics of the strong coupling BCS model, considered as an open system interacting with a thermal bath, is solved rigorously and explicitly in the weak coupling limit and in the infinite-volume limit. The BCS system goes from the normal phase to the ordered phase by bifurcation. Fluctuations around trajectories of intensive observables are Gaussian and Markovian. Thermodynamic phases are global attractors in the physical domain. Structural stability is discussed. The model provides an example of a nonequilibrium statistical mechanical system with phase transition whose irreversible macroscopic dynamics can be calculated exactly from the underlying Hamiltonian quantum mechanics.
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