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  • ASTROPHYSICS  (6,235)
  • AERODYNAMICS  (2,823)
  • Physics
  • 1990-1994  (9,062)
  • 1
    Electronic Resource
    Electronic Resource
    Calcium phosphates in pharmaceutical tableting (1993)
    Springer
    Pharmacy world & science 15 (1993), S. 105-115 
    Details
    ISSN: 1573-739X
    Keywords: Calcium phosphates ; Drug compounding ; Excipients ; Particle size ; Physics ; Powders ; Tablets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Ten commercially available calcium phosphates used for direct tableting were evaluated. The particle size distributions, powder properties, Sorption isotherms and pH values of aqueous slurries were compared. All samples showed good or at least sufficient flowability. Scanning electron micrographs illustrated the different kinds of manufacturing and gave hints on their expectable behaviour under compaction pressure. The sorption isotherms of identical chemical substances, which had been manufactured by different methods, differed strongly. This can be related to their specific surface areas. Most of the hydroxylapatites have large surface areas and can absorb up to more than 15% water at 93% relative humidity. Dibasic calcium phosphate dihydrate was non-hygroscopic and absorbed less than 1% water. With the exception of monobasic calcium phosphate monohydrate all calcium phosphates behaved quite neutral in water. Monobasic calcium phosphate monohydrate can be regarded as a solid acid. Although the calcium phosphates are usually stable substances, the role of crystal water in the case of dibasic calcium phosphate dihydrate and monobasic calcium phosphate monohydrate is problematic due to possible interactions with active ingredients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02113938
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    Paper (German National Licenses)
    Fulltext
  • 2
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    The meaning of hydrophobicity (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dill, K A -- New York, N.Y. -- Science. 1990 Oct 12;250(4978):297-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco 94143.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2218535" target="_blank"〉PubMed〈/a〉
    Keywords: Energy Transfer ; Physical Phenomena ; Physics ; *Protein Conformation ; Proteins/*chemistry ; Solutions
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 3
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    Superconducting Super Collider. Senate issues a stay of execution (1992)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1992-08-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hamilton, D P -- New York, N.Y. -- Science. 1992 Aug 7;257(5071):737.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1496387" target="_blank"〉PubMed〈/a〉
    Keywords: *Government Agencies ; Physical Phenomena ; Physics ; Politics ; *Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 4
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    Science, citation, and funding (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-03-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1991 Mar 22;251(5000):1408-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2006414" target="_blank"〉PubMed〈/a〉
    Keywords: Astronomical Phenomena ; Astronomy ; Physical Phenomena ; Physics ; Publishing/*trends ; Research Support as Topic ; Science/*methods ; Sociology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    An ensemble pulsar time (1993)
    In:  CASI
    Details
    Publication Date: 2004-12-03
    Description: Millisecond pulsars are galactic objects that exhibit a very stable spinning period. Several tens of these celestial clocks have now been discovered, which opens the possibility that an average time scale may be deduced through a long-term stability algorithm. Such an ensemble average makes it possible to reduce the level of the instabilities originating from the pulsars or from other sources of noise, which are unknown but independent. The basis for such an algorithm is presented and applied to real pulsar data. It is shown that pulsar time could shortly become more stable than the present atomic time, for averaging times of a few years. Pulsar time can also be used as a flywheel to maintain the accuracy of atomic time in case of temporary failure of the primary standards, or to transfer the improved accuracy of future standards back to the present.
    Keywords: ASTROPHYSICS
    Type: NASA. Goddard Space Flight Center, The 24th Annual Precise Time and Time Interval (PTTI) Applications and Planning Meeting; p 73-86
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    NASA TECHNICAL REPORTS
  • 6
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    Calculations of the outflow velocity of envelopes of cool giants (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: We study the transfer of momentum from photons to dust grains to (molecular) gas in the outflow around cool giants (carbon-stars, Mira variables and OH/IR stars) beyond the radius where the dust grains condense. The problem is circular: radiation pressure determines the outflow velocity of the dust and thus also the dust density; on the other hand the dust density determines, via radiative transfer effects, the spectrum of the photons and thus the effective radiation pressure. This circular problem is solved by a rapidly converging iterative procedure. We compare our predictions with observed properties of a large sample of OH/IR stars and of Miras and find a good qualitative and quantitative agreement. We confirm a conclusion by Wood et al. (1993) that very luminous OH/IR stars in the Large Magellanic Cloud (LMC) owe their low outflow velocity to the low dust-to-gas ratio, a consequence of the low metallicity of the LMC. Similarly we consider a sample of about 100 OH/IR stars within 200 pc from the galactic center that has an average asymptotic giant branch (AGB) luminosity and an uncommonly high value of v(sub out); we conclude that these stars are probably very metal rich, perhaps even more than the stars in the Baade window studied by Rich (1990).
    Keywords: ASTROPHYSICS
    Type: Astronomy and Astrophysics (ISSN 0004-6361); 286; 2; p. 523-534
    Format: text
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    NASA TECHNICAL REPORTS
  • 7
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    The relationship between the magnetic field in the Martian magnetotail and upstream solar wind parameters (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Magnetic field data measured by the MAGMA instrument in the Martian magnetotail lobes are compared with the ram pressure of the upstream solar wind observed by the TAUS instrument in the circular orbits of the Phobos 2 spacecraft. High correlation was found between the magnetic field intensity in the Martian magnetotail lobes and the solar wind ram pressure. From this relationship the average flaring angle of the Martian magnetotail was determined as approximately 13 deg, and the average magnetosonic Mach number was estimated as approximately 5. The observed relationship between the Martian magnetotail magnetic field intensity and the solar wind magnetic field reflects the correlation of the solar wind magnetic field to the ram pressure providing a value of approximately 7 for the average Alfvenic Mach number. The flaring angle obtained for the Martian magnetotail was found to be an intermediate value between the flaring angle of the magnetotail of the Earth and that of Venus at comparable distances.
    Keywords: ASTROPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 99; A9; p. 17,199-17,204
    Format: text
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    NASA TECHNICAL REPORTS
  • 8
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    Interferometric investigations of compressible dynamic stall over a transiently pitching airfoil (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The compressible dynamic stall flowfield over a NACA 0012 airfoil transiently pitching from 0 to 60 deg at a constant rate under compressible flow conditions has been studied using real-time interferometry. A quantitative description of the overall flowfield, including the finer details of dynamic stall vortex formation, growth, and the concomitant changes in the airfoil pressure distribution, has been provided by analyzing the interferograms. For Mach numbers above 0.4, small multiple shocks appear near the leading edge and are present through the initial stages of dynamic stall. Dynamic stall was found to occur coincidentally with the bursting of the separation bubble over the airfoil. Compressibility was found to confine the dynamic stall vortical structure closer to the airfoil surface. The measurements show that the peak suction pressure coefficient drops with increasing freestream Mach number, and also it lags the steady flow values at any given angle of attack. As the dynamic stall vortex is shed, an anti-clockwise vortex is induced near the trailing edge, which actively interacts with the post-stall flow.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 3; p. 586-593
    Format: text
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    NASA TECHNICAL REPORTS
  • 9
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    Reduction of blade-vortex interaction noise through porous leading edge (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The effect of the porous leading edge of an airfoil on the blade-vortex interaction noise, which dominates the far-field acoustic spectrum of the helicopter, is investigated. The thin-layer Navier-Stokes equations are solved with a high-order upwind-biased scheme and a multizonal grid system. The Baldwin-Lomax turbulence model is modified for considering transpiration on the surface. The amplitudes of the propagating acoustic wave in the near field are calculated directly from the computation. The porosity effect on the surface is modeled in two ways: (1) imposition of prescribed transpiration velocity distribution and (2) calculation of transpiration velocity distribution by Darcy's law. Results show leading-edge transpiration can suppress pressure fluctuations at the leading edge during blade-vortex interaction and consequently reduce the amplitude of propagating noise by 30% at a maximum in the near field.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 3; p. 480-488
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    NASA TECHNICAL REPORTS
  • 10
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    Effect of Reynolds number and turbulence on airfoil aerodynamics at -90-degree incidence (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: A method has been developed for calculating the viscous flow about airfoils with and without deflected flaps at -90 deg incidence. This method provides for the solution of the unsteady incompressible Navier-Stokes equations by means of an implicit technique. The solution is calculated on a body-fitted computational mesh using a staggered-grid method. The vorticity is defined at the node points, and the velocity components are defined at the mesh-cell sides. The staggered-grid orientation provides for accurate representation of vorticity at the node points and the continuity equation at the mesh-cell centers. The method provides for the noniterative solution of the flowfield and satisfies the continuity equation to machine zero at each time step. The method is evaluated in terms of its stability to predict two-dimensional flow about an airfoil at -90-deg incidence for varying Reynolds number and laminar/turbulent models. The variations of the average loading and surface pressure distribution due to flap deflection, Reynolds number, and laminar or turbulent flow are presented and compared with experimental results. The comparisom indicate that the calculated drag and drag reduction caused by flap deflection and the calculated average surface pressure are in excellent agreement with the measured results at a similar Reynolds number.
    Keywords: AERODYNAMICS
    Type: AIAA Journal (ISSN 0001-1452); 32; 3; p. 449-454
    Format: text
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    NASA TECHNICAL REPORTS
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