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  • Animals  (4,976)
  • *Ecosystem  (661)
  • 2005-2009  (5,184)
  • 1
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    Nature Publishing Group (NPG)
    Publication Date: 2009-11-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Check Hayden, Erika -- England -- Nature. 2009 Nov 5;462(7269):21. doi: 10.1038/462021a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19890298" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptation, Physiological/genetics ; Animals ; *Biodiversity ; Databases, Genetic ; Genomics/*trends ; Humans ; International Cooperation ; Species Specificity ; Vertebrates/*genetics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2006-11-04
    Description: This week marks a century since the first description of Alzheimer's disease (AD). Despite approval of several drugs for AD, the disease continues to rob millions of their memories and their lives. Fortunately, many new therapies directly targeting the mechanisms underlying AD are now in the pipeline. Among the investigative AD therapies in clinical trials are several strategies to block pathogenic amyloid-beta peptides and to rescue vulnerable neurons from degeneration. Complementary but less mature strategies aim to prevent the copathogenic effects of apolipoprotein E and the microtubule-associated protein tau. New insights into selective neuronal vulnerability and the link between aging and AD may provide additional entry points for therapeutic interventions. The predicted increase in AD cases over the next few decades makes the development of better treatments a matter of utmost importance and urgency.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544944/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544944/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Roberson, Erik D -- Mucke, Lennart -- AG011385/AG/NIA NIH HHS/ -- AG022074/AG/NIA NIH HHS/ -- K08 NS054811/NS/NINDS NIH HHS/ -- K08 NS054811-01/NS/NINDS NIH HHS/ -- NS054811/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 2006 Nov 3;314(5800):781-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, CA 94158, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17082448" target="_blank"〉PubMed〈/a〉
    Keywords: Alzheimer Disease/pathology/physiopathology/*therapy ; Amyloid beta-Peptides/immunology/metabolism ; Animals ; Clinical Trials as Topic ; Enzyme Inhibitors/therapeutic use ; Humans ; Immunization, Passive ; Nootropic Agents/therapeutic use ; Vaccination
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2005-10-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sharp, Phillip A -- New York, N.Y. -- Science. 2005 Oct 7;310(5745):17.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16210500" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bioterrorism ; Containment of Biohazards ; Disease Outbreaks/history ; Editorial Policies ; *Genes, Viral ; Genome, Viral ; History, 20th Century ; Humans ; Influenza A virus/*genetics/pathogenicity ; Influenza, Human/epidemiology/history/*virology ; Information Dissemination ; Mice ; *Publishing ; Security Measures ; Sequence Analysis, DNA ; Virulence
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2009-08-29
    Description: Northern Hemisphere surface temperature reconstructions suggest that the late twentieth century was warmer than any other time during the past 500 years and possibly any time during the past 1,300 years (refs 1, 2). These temperature reconstructions are based largely on terrestrial records from extra-tropical or high-elevation sites; however, global average surface temperature changes closely follow those of the global tropics, which are 75% ocean. In particular, the tropical Indo-Pacific warm pool (IPWP) represents a major heat reservoir that both influences global atmospheric circulation and responds to remote northern high-latitude forcings. Here we present a decadally resolved continuous sea surface temperature (SST) reconstruction from the IPWP that spans the past two millennia and overlaps the instrumental record, enabling both a direct comparison of proxy data to the instrumental record and an evaluation of past changes in the context of twentieth century trends. Our record from the Makassar Strait, Indonesia, exhibits trends that are similar to a recent Northern Hemisphere temperature reconstruction. Reconstructed SST was, however, within error of modern values from about ad 1000 to ad 1250, towards the end of the Medieval Warm Period. SSTs during the Little Ice Age (approximately ad 1550-1850) were variable, and approximately 0.5 to 1 degrees C colder than modern values during the coldest intervals. A companion reconstruction of delta(18)O of sea water-a sea surface salinity and hydrology indicator-indicates a tight coupling with the East Asian monsoon system and remote control of IPWP hydrology on centennial-millennial timescales, rather than a dominant influence from local SST variation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Oppo, Delia W -- Rosenthal, Yair -- Linsley, Braddock K -- England -- Nature. 2009 Aug 27;460(7259):1113-6. doi: 10.1038/nature08233.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Geology and Geophysics, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543, USA. doppo@whoi.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19713927" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Atmosphere/analysis ; Calibration ; History, 15th Century ; History, 16th Century ; History, 17th Century ; History, 18th Century ; History, 19th Century ; History, 20th Century ; History, 21st Century ; History, Ancient ; History, Medieval ; Ice Cover ; India ; Indonesia ; Oceans and Seas ; Oxygen Isotopes ; Pacific Ocean ; Plankton/metabolism ; Rain ; Records as Topic ; Salinity ; Seasons ; Seawater/*analysis ; *Temperature ; Time Factors ; Tropical Climate ; Weather
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 5
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2005-09-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gramling, Carolyn -- New York, N.Y. -- Science. 2005 Sep 23;309(5743):1992.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16179456" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Awards and Prizes ; Hemiptera/*growth & development ; History, 21st Century ; Indiana ; *Multimedia/history ; *Photography/history ; *Video Recording/history
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2006-01-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 2006 Jan 6;311(5757):35.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16400127" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Birds ; China/epidemiology ; Government Agencies/*organization & administration ; History, 21st Century ; Humans ; Influenza in Birds/*epidemiology ; Influenza, Human/*epidemiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2006-09-23
    Description: Science and the National Science Foundation announce the winners and honorable mentions in the categories of photography, illustration, informational graphics, noninteractive multimedia, and interactive multimedia in this year's Science and Engineering Visualization Challenge.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chatterjee, Rhitu -- New York, N.Y. -- Science. 2006 Sep 22;313(5794):1730-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16990531" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Audiovisual Aids ; *Awards and Prizes ; Computer Graphics ; *Diagnostic Imaging ; Humans ; Image Processing, Computer-Assisted ; Imaging, Three-Dimensional ; Multimedia ; Photography
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2007-09-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lester, Benjamin -- New York, N.Y. -- Science. 2007 Sep 28;317(5846):1858-63.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17901312" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Audiovisual Aids ; *Awards and Prizes ; Computer Graphics ; Computer Simulation ; *Diagnostic Imaging ; Humans ; Internet ; Photography ; Tomography, X-Ray Computed ; User-Computer Interface ; Video Recording
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2007-02-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stokstad, Erik -- New York, N.Y. -- Science. 2007 Feb 2;315(5812):585-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17272693" target="_blank"〉PubMed〈/a〉
    Keywords: *Budgets ; *Ecosystem ; Financing, Government ; *Marine Biology ; *Oceanography ; Oceans and Seas ; *Research Support as Topic ; Seawater ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2008-09-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zelkowitz, Rachel -- New York, N.Y. -- Science. 2008 Sep 26;321(5897):1768. doi: 10.1126/science.321.5897.1768.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18818337" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Audiovisual Aids ; *Awards and Prizes ; Computer Graphics ; Humans ; Imaging, Three-Dimensional ; Internet ; Microscopy, Electron ; Multimedia ; Photography
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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