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  • bic Book Industry Communication::M Medicine  (1,212)
  • Organic Chemistry
  • 2020-2024  (1,213)
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  • 1
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    10th Anniversary of Biomedicines—Biomarkers in Pain (2024)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-01-08
    Description: Pain biomarkers are biological indicators or measurable characteristics that can provide information about the presence, severity, or underlying mechanisms of pain. They are valuable for several reasons: Diagnosis and differential diagnosis: Biomarkers can help in the diagnosis of various pain conditions and differentiate between different types of pain, such as neuropathic, inflammatory, or nociceptive pain. This can lead to more accurate and timely diagnoses, which in turn can improve patient care. Monitoring treatment efficacy: Pain biomarkers can be used to track how well treatments are working for individuals suffering from chronic pain conditions. This allows healthcare providers to make informed decisions about adjusting treatment plans, optimizing pain management, and avoiding unnecessary or ineffective interventions. Drug development and testing: Biomarkers play a crucial role in the development of new pain medications and therapies. They can help researchers identify potential drug targets, screen compounds for their pain-relieving properties, and assess the safety and efficacy of experimental treatments in clinical trials. Personalized medicine: Pain biomarkers may, in a future, contribute to treatments, tailored to an individual's unique genetic and biological disposition. Reducing opioid misuse: By using biomarkers to assess pain and treatment responses, healthcare providers can make more informed decisions about opioid prescriptions, potentially reducing the overuse and abuse of these medications.
    Keywords: analgesia ; biomarker ; CSF ; cytokine ; inflammation ; neuropathy ; neurotransmitter ; pain ; QoL ; sensitization ; sensory ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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  • 2
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    10th Anniversary of JCM (2023)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-09-11
    Description: The year 2021 marks the 10th anniversary of Journal of Clinical Medicine, and as one of the major sections of JCM, we are launching a 10th anniversary Special Issue in the section “Gastroenterology & Hepatopancreatobiliary Medicine”. We accepted papers for the Special Issue, titled "Recent diagnostic and therapeutic advance in Gastroenterology & Hepatopancreatobiliary Medicine". This medical field is a complex and wide-ranging field that deals with diseases in multiple organs such as the gastrointestinal tract and hepatobiliary pancreas. With recent advances in diagnostic imaging and interventional treatment, those in endoscopic diagnosis and treatment, those in functional test and those in genetic diagnosis and drug therapy, including the molecular-targeted therapy, many new medical findings have been accumulated. In this Special Issue, we looked for reports that make full use of advances in diagnostics and therapeutics in the field of Gastroenterology and Hepatopancreatobiliary Medicine.
    Keywords: TXI ; sessile serrated lesion ; hyperplastic polyp ; colonoscopy ; endoscopic submucosal dissection ; colorectal tumor ; traction method ; carbon dioxide ; CO2 insufflation ; abdominal pain ; abdominal distention ; transnasal endoscopy ; health check ; tranexamic acid ; gastrointestinal bleeding ; mortality ; thromboembolic events ; liver metastases ; colorectal liver metastases ; non-colorectal and non-neuroendocrine liver metastases ; liver resection ; Crohn’s disease ; biologics ; small-molecule drugs ; health-related quality of life (HRQoL) ; gastric cancer ; gastric cancer screening ; endoscopy ; H. pylori ; eradication therapy ; n/a ; functional bowel disorders ; gut microbiota ; personalized diet ; machine learning ; personalized medicine ; Turkey ; machine perfusion ; normothermic ; hypothermic ; liver transplant ; survival ; ustekinumab ; perianal fistula ; radiological fistula remission ; metastatic pancreatic carcinoma ; FOLFIRINOX ; sarcopenia ; oxaliplatin ; L3 skeletal muscle index ; percutaneous endoscopic gastrostomy ; prognostic factor ; bic Book Industry Communication::M Medicine
    Language: English
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  • 3
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    3D Analysis of Human Movement, Sport, and Health Promotion (2024)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-01-08
    Description: The 3D analysis of human movement aims to objectively and quantitatively assess motor functions and alterations. It is a valuable method for sport scientists, coaches, and clinicians to evaluate sport performance, common movements, and alterations. The feasibility of 3D analysis is increasing because it can be adopted both in a laboratory setting or directly in the field, in static or dynamic conditions, and for physiological or pathological movements. This evaluation technique can be adopted for many people, including children, adolescents, adults, and older people, whether they are sedentary or athletes and whether they are healthy or motor-impaired people.
    Keywords: virtual reality ; augmented reality ; lifelogging ; mirror world ; health ; posture training ; feedback ; COVID-19 ; neck-shoulder-region ; shoulder protraction ; upper crossed syndrome ; posture weakness ; physical inactivity ; sedentary behavior ; soccer ; climbing ; exhaustion ; fatigue ; training ; machine learning ; sports ; gender ; data mining ; artificial intelligence ; posture ; reproducibility ; mobile app ; movement ; kinesiology ; sport performance ; inertial sensor ; inertial sensor device ; inertial measurement unit ; training load ; external load ; physical demand ; handstand ; postural control ; postural balance ; sEMG ; stabilometric assessment ; exercise ; Nordic walking ; walking ; 3D kinematics ; biomechanics ; gait analysis ; kyphosis ; spinal mouse ; photogrammetry ; postural evaluation ; bicycle ; cyclists ; saddle pressure ; perineal pressure ; urogenital system ; injury prevention ; cervical ROM ; elastic taping ; neck pain ; musculoskeletal health ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 4
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    3D Printed Materials Dentistry (2023)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-04-05
    Description: The Special Issue reprint covers a wide range of applications of 3D-printing in dentistry. Five out of eleven research papers deal with applications of 3D printing in orthodontics, one study presents a 3D-printed fitting system for the FFP2 that were applied during the COVID-19 pandemic, and the others address applications in prosthodontics and restorative dentistry.
    Keywords: three-dimensional printing ; dimensional stability ; dental models ; methodology ; accuracy ; storage ; bonding tray ; 3D-printing ; intraoral scanning ; shore hardness ; dental students ; cavity preparation ; 3D-printed teeth ; teachers’ evaluation ; additive manufacturing ; 3D printing ; fused filament fabrication ; fused deposition modeling ; digital workflow ; dentistry ; aligner ; Micro-CT ; PETG ; thermoforming ; material characteristics ; interim crowns ; provisional crowns ; trueness ; layer thickness ; margin quality ; support structure ; postcuring ; digital orthodontic appliance ; CAD/CAM ; polyether ether ketone (PEEK) ; finite element analysis (FEA) ; mechanical analysis ; orthodontic ; skeletal anchorage ; temporary anchorage device ; printed appliance ; metal printing ; flexural modulus ; hardness ; surgical template ; sterilization ; 3D-face-scanning ; surgical mask ; FFP2 respirator ; mask fitter ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Language: English
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  • 5
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    A ciência como profissão : médicos, bacharéis e cientistas no Brasil (1895-1935) (2021)
    SciELO Books - Editora FIOCRUZ
    Details
    Publication Date: 2023-12-21
    Description: O livro aborda o processo de especialização da atividade intelectual no Brasil durante as três primeiras décadas do século XIX, ao mesmo tempo em que analisa a emergência do ´cientista´ nesse processo, no qual já se anunciava o divórcio entre as ´humanidades´e as ´ciências duras´.
    Keywords: R5-920 ; bic Book Industry Communication::M Medicine
    Language: Portuguese
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  • 6
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    A Commemorative Issue in Honor of Centennial of the Discovery of Vitamin D-The Central Role of Vitamin D in Physiology (2023)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-04-05
    Description: This reprint is about vitamin D, a molecule that can be absorbed from certain foods, such as fatty fish, which can also be produced endogenously when we expose our skin to sufficient doses of ultraviolet B radiation. When vitamin D is metabolized into 1,25(OH)2D3 (also called calcitriol), it acts as a high-affinity ligand for the transcription factor VDR, i.e., it has direct effects on gene regulation. The key physiological functions of vitamin D are the regulation of calcium homeostasis, which is essential for bone mineralization, and the modulation of the immune system by stimulating innate immunity and preventing overreactions of adaptive immunity. This reprint presents recent developments and the latest research in the fascinating broad range of today’s vitamin D biology, from evolution to systems biology.
    Keywords: vitamin D ; VDR ; target genes ; chromatin ; epigenome ; transcriptome ; vitamin D signaling ; 25-hydroxyvitamin D ; 1,25-(OH)2D3 ; antitumor action ; breast cancer ; case-control studies ; colorectal cancer ; cohort studies ; ecological studies ; epidemiological studies ; randomized controlled trials ; UVB ; vitamin D receptor ; 3D structure ; structural analysis ; molecular recognition ; protein–ligand interactions ; coregulators ; acute myeloid leukemia ; blast ; 1,25-dihydroxyvitamin D ; analogs ; all-trans-retinoic acid ; differentiation ; immunomodulation ; evolution ; energy metabolism ; immune system ; calcium homeostasis ; migration of Homo sapiens ; influenza ; SARS-CoV-2 ; lung ; inflammation ; infantile hypercalcemia type 1 ; idiopathic infantile hypercalcemia ; CYP24A1 ; 25-hydroxyvitamin D 24-hydroxylase ; hypercalcemia ; 24,25-dihydroxyvitamin D3 ; fracture repair ; diet ; transcellular ; absorption ; diffusion ; intestine ; homeostasis ; parathyroid hormone ; gestational diabetes ; preeclampsia ; preterm birth ; ovarian cancer ; vitamin D analogs ; vitamin D deficiency ; single high dose ; vitamin D3 supplementation ; proinflammatory cytokines ; IL6 ; IL8 ; TNF ; 25(OH)D3 ; brain ; development ; neuroprotection ; disease mechanisms ; genetic risk ; heritability ; personalized supplementation ; genome-wide association study ; Mendelian randomization ; lumisterol ; anti-inflammatory ; ACE2 ; Mpro ; RdRp ; month of birth ; muscle ; pregnancy ; older adults ; metabolites ; hybrids and VDR nonsecosteroidal ligands ; nongenomic response ; PDIA3 ; ultraviolet radiation ; megalin ; mitochondria ; vitamin D metabolism ; fibroblast growth factor-23 ; klotho ; 1α-hydroxylase ; RAAS ; systems biology ; cell differentiation ; prostate cancer ; n/a ; bone ; osteoblasts ; differentiation and mineralization ; McCollum ; sunlight ; rickets ; food fortification ; vitamin D2 ; vitamin D3 ; COVID-19 ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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  • 7
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    A Cosmopolítica da gestação, do parto e do pós-parto : autoatenção e medicalização entre os índios Munduruku (2021)
    SciELO Books - Editora FIOCRUZ | Editora FIOCRUZ
    Details
    Publication Date: 2023-12-21
    Description: A pesquisadora Raquel Paiva Dias-Scopel, do Instituto Leônidas e Maria Deane (ILMD/Fiocruz Amazônia), levanta questões sobre a valorização e respeito à diversidade étnica e cultural dos povos indígenas e a difícil interface com o processos de medicalização e do direito ao acesso aos serviços de saúde biomédicos. O livro é parte da Coleção Saúde dos Povos Indígenas, da Editora Fiocruz e partiu da tese de doutorado defendida em 2014 no Programa de Pós-Graduação em Antropologia Social da Universidade Federal de Santa Catarina (UFSC). Foi publicado pela primeira vez em 2015 pela Associação Brasileira de Antropologia com o título A Cosmopolítica da Gestação, Parto e Pós-Parto: práticas de autoatenção e processo de medicalização entre os índios Munduruku. No prefácio da primeira edição, sua orientadora, a doutora em antropologia e professora titular da UFSC, Esther Jean Langdon, ressalta que o conceito fundamental deste livro é da autoatenção, que aponta para o reconhecimento da autonomia e da criatividade da coletividade, principalmente da família, como núcleo que articula os diferentes modelos de atenção ou cuidado da saúde.
    Keywords: R5-920 ; bic Book Industry Communication::M Medicine
    Language: Portuguese
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  • 8
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    A democracia inconclusa : um estudo da reforma sanitária brasileira (2021)
    SciELO Books - Editora FIOCRUZ
    Details
    Publication Date: 2023-12-21
    Description: Trata do papel dos movimentos sociais em saúde no processo de reformulação da política de saúde, plasmado na Constituição de 1988 e denominado de Reforma Sanitária brasileira. Os percalços da sua implementação são analisados no contexto do processo de democratização do País ocorrido nos últimos 10 anos. A autora contribui para a interpretação da problemática da saúde no Brasil contemporâneo, sem a qual não se pode falar em democracia e cidadania. Através da leitura deste trabalho, os cientistas políticos e os profissionais de saúde poderão refletir acerca do lugar que ocupam no sistema e nos serviços de saúde, bem como das articulações de suas representações com a política de saúde.
    Keywords: R5-920 ; bic Book Industry Communication::M Medicine
    Language: Portuguese
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  • 9
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    A dinâmica do sistema produtivo da saúde : inovação e complexo econômico-industrial (2021)
    SciELO Books - Editora FIOCRUZ
    Details
    Publication Date: 2023-12-21
    Description: Para que, no futuro desejado, conforme-se no Brasil um sistema de saúde universal, integral e equânime, o Estado deve ter um papel decisivo na articulação das duas dimensões da saúde: a social e a econômica. É o que defendem os autores deste livro. Um Complexo Econômico-Industrial da Saúde (CEIS) frágil não atende às exigências de elevação da competitividade brasileira no cenário internacional. Mas não é só isso: essa fragilidade afeta sobremaneira a capacidade de resposta às necessidades sanitárias da população. “Gostaríamos que esta publicação se configurasse, sobretudo, como um convite para o debate e para o fortalecimento deste campo científico, com um padrão de desenvolvimento que articule, ao mesmo tempo, o dinamismo econômico com os direitos sociais e a conformação de um Estado de bem-estar no Brasil”, diz o secretário de Ciência, Tecnologia e Insumos Estratégicos do Ministério da Saúde, Carlos Gadelha, coordenador do livro. A publicação apresenta a dinâmica dos investimentos no complexo produtivo da saúde, no mundo e no Brasil, analisando seus diferentes subsistemas: de base química e biotecnológica; de base mecânica, eletrônica e de materiais; e de serviços de saúde. Ao final, traz uma síntese analítica e discute políticas para o desenvolvimento do CEIS.
    Keywords: R5-920 ; MEDICAL ; bic Book Industry Communication::M Medicine
    Language: Portuguese
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  • 10
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    A endemia hansênica: uma perspectiva multidisciplinar (2021)
    SciELO Books - Editora FIOCRUZ
    Details
    Publication Date: 2023-12-21
    Description: Usando metodologia originária da antropologia social e cultural, os autores exploram as representações e estratégias de pacientes e dos trabalhadores de saúde envolvidos com a hanseníase e desevendam a trama de relações, preconceitos e medos que essa doença apresenta. Estigma, depressão, negação da enfermidade, desconfiança, lesões orgânicas, mal-estar, tudo o que aparece misturado na demanda de doentes e comunicantes é, neste trabalho, tratado a partir de uma abordagem que contempla também os aspectos históricos estruturais. Enfim: um estudo de caso que questiona muitos outros casos, uma vez que, a partir da hanseníase, fala sobre a própria prática da saúde pública.
    Keywords: R5-920 ; Hanseníase ; bic Book Industry Communication::M Medicine
    Language: Portuguese
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