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  • Articles  (42)
  • Nature Publishing Group  (42)
  • 2020-2024
  • 1995-1999  (42)
  • Process Engineering, Biotechnology, Nutrition Technology  (42)
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  • Articles  (42)
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  • 1
    Electronic Resource
    Electronic Resource
    Public information, private money (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 491-491 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The announcement of a new genomics company—a collaboration between the Institute for Genome Research (TIGR) and Perkin-Elmer—that promises to sequence the entire human genome in three years at a total cost of only $200 million, has raised again an important question that ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-491a
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  • 2
    Electronic Resource
    Electronic Resource
    Keep the story straight (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 491-491 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Keeping a message simple is the best way to avoid misunderstandings. Accordingly, biotechnology company executives should convey information to the markets and media in a straightforward manner. In past weeks, however, instances of inept information management on the part of company management have ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-491b
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  • 3
    Electronic Resource
    Electronic Resource
    Why pharmacogenomics? Why now? (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 492-493 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The vision of pharmacogenomics is that the discovery of genetic variances that affect drug action will lead to the development of new diagnostic procedures and therapeutic products that enable drugs to be prescribed selectively to patients for whom they will be effective and safe. Recent articles ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-492
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  • 4
    Electronic Resource
    Electronic Resource
    Transferring EU-funded biotechnology research to European bioindustry (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 494-494 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The European Union (EU) is currently deliberating the content of, and budget for, its next scientific research and development program, Framework 5. This will begin in 1999 and, under current proposals, life sciences research will have a budget of over 2.5 billion ECUs ($2.8 billion). ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-494
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  • 5
    Electronic Resource
    Electronic Resource
    Do corporate gifts compromise biotech researchers? (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 495-495 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] With the news this past April that the US Securities and Exchange Commission (SEC) has begun to crack down on classic insider trading schemes by biomedical researchers, the biotechnology industry has begun to look more closely at relationships between academic researchers and the private sector ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-495
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  • 6
    Electronic Resource
    Electronic Resource
    deCODE deferred (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 496-496 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: It may be of interest to your readers to learn that the Icelandic government has now been forced to postpone a bill designed to give deCODE Genetics an exclusive license to collect current and retrospective medical information about all Icelanders into a centralized, comprehensive ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-496a
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  • 7
    Electronic Resource
    Electronic Resource
    Unfair treatment (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 496-496 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: After reading Vicki Brower's “Prostate cancer link sours IGF-1” (Nature Biotechnology 16:223, March 1998), I felt compelled to reply to this rather one-sided analysis of IGF-1 therapy. While talk continues of the “side effects” of IGF-1, few of these side ...
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    URL: http://dx.doi.org/10.1038/nbt0698-496b
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  • 8
    Electronic Resource
    Electronic Resource
    Gene therapy or antisense (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 496-496 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: With statements by Friedman1 that gene therapy, while not a failure, is simply too immature to deliver on its promises, and Varmus2 that gene therapy is not ready for prime time, earlier excitement about the field has cooled, despite some successes3. And as the US National Institutes ...
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    URL: http://dx.doi.org/10.1038/nbt0698-496c
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  • 9
    Electronic Resource
    Electronic Resource
    Business and Regulatory News (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 497-499 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Monsanto buys more seed Monsanto (St. Louis, MO) announced the intent to acquire two seed companies, DeKalb Genetics (Dekalb, IL) and Delta & Pine Land (D&P; Scott, MS) last month. “What both these acquisitions will allow us to do is broaden the availability of our agronomic traits ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-497
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  • 10
    Electronic Resource
    Electronic Resource
    Research News (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 500-500 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Staphylococci get the RAP By blocking a bacterial signaling pathway, a vaccine developed by researchers at the University of California, Davis School of Medicine may offer a new treatment for patients who become infected with antibiotic-resistant bactera. Staphylo coccus aitreusam cause ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-500
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  • 11
    Electronic Resource
    Electronic Resource
    This Month in Nature Biotechnology (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 501-501 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] By introducing 2′-amino pyrimidine residues into a catalytically active protein kinase Cα ribozyme, Sioud and Sorensen have designed a catalyst that is over 14,000-fold more stable than its unsubstitirted counterpart yet retains most of its biological activity. A single injection of the ...
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    URL: http://dx.doi.org/10.1038/nbt0698-501
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  • 12
    Electronic Resource
    Electronic Resource
    Net to help catch NZ serum forgers (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 503-503 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A new Internet-based electronic certification system for bovine serum imported into Europe from New Zealand could put an end to much of the anxiety that currently plagues manufacturers of biological drugs. According to Caryll Shailer, a veterinarian from New Zealand's Ministry of Agriculture and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-503a
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  • 13
    Electronic Resource
    Electronic Resource
    British Biotech taints British biotech (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 503-504 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] What lessons should be learned from a fracas that blew up around unduly positive statements made in the past by British Biotech (Oxford, UK) executives about two of the firm's drugs in development? Until now, the company had exemplary relationships with investors and had been widely regarded as a ...
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    URL: http://dx.doi.org/10.1038/nbt0698-503b
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  • 14
    Electronic Resource
    Electronic Resource
    E&Y notes shift in new BT activity (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 504-505 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] “Continental shift”—the subtitle of the 1998 status report from accountants Ernst & Young (E&Y; New York) on biotechnology in Europe—highlights the surge of investment activity in Europe outside the UK in the past few months. E&Y released both its European and US ...
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    URL: http://dx.doi.org/10.1038/nbt0698-504
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  • 15
    Electronic Resource
    Electronic Resource
    US officials clash with industry executives over BWC (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 506-506 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Heightened interest in biological warfare issues among top US officials—including some in the arms control and disarmament agency and the department of defense—is leading them rather abruptly to champion international treaty-enforcement negotiations. However, despite recent jawboning ...
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    URL: http://dx.doi.org/10.1038/nbt0698-506a
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  • 16
    Electronic Resource
    Electronic Resource
    Drug bill cuts force firms overseas (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 506-507 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Japan's flagging National Health Insurance (NHI) system is ready to face full-scale renovation after the government recently took a significant step toward the introduction of a new reference price system that will set drug prices at more competitive rates. This April, Japan's Ministry of Health ...
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    URL: http://dx.doi.org/10.1038/nbt0698-506b
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  • 17
    Electronic Resource
    Electronic Resource
    Chips advance but cost constraints remain (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 509-509 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] “We Want Cheaper Machines.” That declaration, on a slide shown at the 30th Annual Oak Ridge Conference on Miniaturization of Analytical Systems (Raleigh, NC, April 23–24, 1998), encapsulates a fundamental barrier that stands between chip-based methods and their markets in clinical ...
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    URL: http://dx.doi.org/10.1038/nbt0698-509
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  • 18
    Electronic Resource
    Electronic Resource
    From Genetic Systems to Seattle Genetics (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 508-508 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The pedigree of Seattle Genetics and predecessor, BMS's Seattle biotechnology arm, reaches far back in the history of modern biotechnology. In the early 1980s, Bristol-Myers (pre-Squibb) began investing heavily in molecular biology and immunology. In 1985, Bristol-Myers also became one of ...
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    URL: http://dx.doi.org/10.1038/nbt0698-508b
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  • 19
    Electronic Resource
    Electronic Resource
    BMS cancer spin-off raises first finance (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 508-508 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Nearly a year after Bristol-Myers Squibb (BMS; Princeton, NJ) announced its intention to close the Seattle biotechnology site, two former BMS molecular immunologists have secured rights to the cancer-targeting program on which they had worked for a decade, creating Seattle Genetics (Bothell, WA) to ...
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    URL: http://dx.doi.org/10.1038/nbt0698-508a
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  • 20
    Electronic Resource
    Electronic Resource
    Central criminal DNA database created in Germany (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 510-511 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Just before the German federal elections in September, the German minister of internal affairs, Manfred Kanther, has created a central DNA-analysis database at the German Federal Criminal Police Office (Bundeskriminalamt, BKA) in Wiesbaden “as a weapon against criminals.” Although ...
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    URL: http://dx.doi.org/10.1038/nbt0698-510
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  • 21
    Electronic Resource
    Electronic Resource
    Researcher and Amgen baffled by Love letter (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 511-511 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Amgen (Thousand Oaks, CA) has been accused of blocking the development of a potentially lifesaving invention. Consumer advocate and onetime presidential candidate Ralph Nader and director of the Consumer Project on Technology James Love wrote an open letter to the White House in April alleging that ...
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    URL: http://dx.doi.org/10.1038/nbt0698-511
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  • 22
    Electronic Resource
    Electronic Resource
    Shining a light on protein sociobiology (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 514-515 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The ability to determine where and when protein partnerships form in the living cell is of fundamental importance to understanding biological processes. In this issue, Mahajan and colleagues1 report on a fluorescence imaging technique that allows visualization of physical interactions between two ...
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    URL: http://dx.doi.org/10.1038/nbt0698-514
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  • 23
    Electronic Resource
    Electronic Resource
    Revolution on a square centimeter (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 513-514 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The detection of microorganisms is important in disease diagnosis, in guaranteeing the safety of the food and water supply, and in ensuring public safety from the threat of biological warfare agents. Simple, rapid, and easy-to-perform microbiological tests would have many benefits, but progress ...
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    URL: http://dx.doi.org/10.1038/nbt0698-513
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  • 24
    Electronic Resource
    Electronic Resource
    The ins and outs of on and off (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 516-516 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The holy grail for many clinicians is to intervene therapeutically at the level of the genome, either to correct a congenital disorder or to bolster cellular function during an insult. This decade has witnessed the emergence of the nascent discipline of gene therapy with, to date, a disappointingly ...
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    URL: http://dx.doi.org/10.1038/nbt0698-516
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  • 25
    Electronic Resource
    Electronic Resource
    DNA vaccines with a kick (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 517-518 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Less is more. This is particularly true for DNA vaccines, where the aim is to deliver as small an amount of vector as possible to evoke a potent and protective immune response. Two recent reports demonstrate that DNA vaccine efficacy can be greatly enhanced using plasmids designed to launch ...
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    URL: http://dx.doi.org/10.1038/nbt0698-517
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  • 26
    Electronic Resource
    Electronic Resource
    Bcl-2 and Bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 547-552 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] It has been hypothesized that interaction of Bcl-2 and Bax may regulate apoptosis. The spatial and temporal interaction of Bcl-2 and Bax at the single cell level has not, however, been demonstrated. To achieve this goal, we have developed two-fusion FRET (fluorescence resonance energy transfer). ...
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    URL: http://dx.doi.org/10.1038/nbt0698-547
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  • 27
    Electronic Resource
    Electronic Resource
    A nuclease-resistant protein kinase Cα ribozyme blocks glioma cell growth (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 556-561 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We investigated the cleavage activity, stability, and efficacy of 2′-amino pyrimidine modified ribozymes on malignant glioma growth. A synthetic protein kinase Cα (PKCα) ribozyme with complete pyrimidine nucleotide substitution retained a comparable cleavage activity compared with ...
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    URL: http://dx.doi.org/10.1038/nbt0698-556
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  • 28
    Electronic Resource
    Electronic Resource
    Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricated bioelectronic chips (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 541-546 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Escherichia coli were separated from a mixture containing human blood cells by means of dielec-trophoresis and then subjected to electronic lysis followed by proteolytic digestion on a single microfabricated bioelectronic chip. An alternating current electric field was used to direct the bacteria ...
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    URL: http://dx.doi.org/10.1038/nbt0698-541
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  • 29
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    Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 553-555 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have developed a tetracycline-regulatable adenoviral transfection system that mediates efficient long-term transfer of genes into neuronal cells in vivo. This system allows gene expression to be switched on, then off, and back on again simply by administering or removing doxycycline from the ...
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  • 30
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    Enhancing immune responses using suicidal DNA vaccines (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 562-565 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We describe a DNA vaccine strategy that allows antigens to be produced in vivo in the context of an alphaviral replicon. Mice immunized with such vectors developed humoral and cellular immune responses at higher levels than mice that received a conventional DNA vaccine vector. Immunized animals ...
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    URL: http://dx.doi.org/10.1038/nbt0698-562
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  • 31
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    Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 566-571 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A global methylation-based technique was used to identify, display, and quantitate the in vivo occupancy of numerous protein-binding sites within the Escherichia coli genome. The protein occupancy profiles of these sites showed variation across different growth conditions and genetic backgrounds. ...
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    URL: http://dx.doi.org/10.1038/nbt0698-566
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  • 32
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    An integrated microbial process for the bioremediation of soil contaminated with toxic metals (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 572-575 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Microbially catalyzed reactions, which occur in the natural sulfur cycle, have been integrated in a microbiological process to remove toxic metals from contaminated soils. Bioleaching using sulfuric acid produced by sulfur-oxidizing bacteria was followed by precipitation of the leachate metals as ...
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    URL: http://dx.doi.org/10.1038/nbt0698-572
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  • 33
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    Surface display of Zymomonas mobilis levansucrase by using the ice-nucleation protein of Pseudomonas syringae (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 576-580 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The ice-nucleation protein (Inp) is a glycosyl phosphatidylinositol-anchored outer membrane protein found in some Gram-negative bacteria. Using Pseudomonas syringae Inp as an anchoring motif, we investigated the functional display of a foreign protein, Zymomonas mobilis levansucrase (LevU), on the ...
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    URL: http://dx.doi.org/10.1038/nbt0698-576
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  • 34
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    Recent patent applications in transgenics (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 589-589 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Patent# Subject Assignee Author Date Status US 9719390 New KUZ polypeptides, members of the ADAM family of metalloprotease; useful in neural partitioning and development. Univ. California (Oakland, CA); Yale Univ. (New Haven, CT) Pan D, Rooke J, Rubin GM, Xu T, Yavari R 7/23/97 A1 AU ...
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    URL: http://dx.doi.org/10.1038/nbt0698-589
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    Cloning of cell-specific secreted and surface proteins by subtractive antibody screening (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 581-586 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To identify and clone genes that encode cell- or tissue-specific secreted and surface proteins, a polyclonal antiserum was raised against a complex mixture of surface or secreted proteins from the target cell, followed by immunodepletion of antibodies that recognize proteins from a nontarget cell ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-581
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    When failing to offer your best mode leads to antitrust (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 587-588 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Antitrust suits are not the exclusive domain of megacompanies: Inventors who intentionally falsify a patent application may be slapped with these suits as well.It seems that every day the newspapers report Microsoft's (Redmond, WA) ongoing battles with the US Justice Department (Washington, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-587
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    Websites for the business of biotechnology (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 590-590 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] For those interested in the business of biotechnology, the Internet is an essential tool for keeping current with company information as well as the financial markets. It is also the great equalizer, accessible to everyone from undergraduates planning their futures and individual investors to big ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0698-590
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    Antibodies (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 591-591 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Androgen receptor antibody DAKO (Carpenteria, CA) offers an antibody against androgen receptors, an intracellular protein that mediates biochemical actions of physiological androgen steroids and testosterone. Androgen receptors are expressed in the majority of prostate, breast, and ovarian ...
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    URL: http://dx.doi.org/10.1038/nbt0698-591
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    Extremophiles (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 593-594 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Unusual and useful molecules are found in life on the edge of environmental tolerance.Life-forms that can withstand and even thrive under conditions of either very high or very low temperature, pressure, and pH and salt concentration are perhaps some of the oldest on Earth. The unique genomes of ...
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    URL: http://dx.doi.org/10.1038/nbt0698-593
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    People (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 592-592 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Maxim Pharmaceuticals (San Diego, CA) has announced three additions to its management team. Geoffrey B. Altman has been named senior director, marketing and sales. Previously, Mr. Altman was director of worldwide marketing at Agouron Pharmaceuticals. F. David King, formerly director of business ...
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    URL: http://dx.doi.org/10.1038/nbt0698-592
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    The engineering of drug discovery (1998)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 16 (1998), S. 313-313 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Present-day industrialized drug discovery is built on a technological foundation consisting of combinatorial chemistry, genomics, and high-throughput screening—a source of novel molecules, a source of novel targets, and a method to assay one against the other, respectively. These core ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0498-313
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    Engineering human glycoprotein hormone superactive analogues (1996)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 14 (1996), S. 1257-1263 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We report the generation of superactive analogues of human glycoprotein hormones, with potential applications in thyroid and reproductive disorders. Current biological and structural data were used to rationalize mutagenesis. The 11–20 region in the α-subunit with a cluster of lysine ...
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    URL: http://dx.doi.org/10.1038/nbt1096-1257
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