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  • bic Book Industry Communication::M Medicine
  • Firenze University Press  (8)
  • Collège de France  (1)
  • English  (9)
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  • 1
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    Firenze University Press
    Publication Date: 2022-06-02
    Description: TOX is a manual aimed primarily at the Toxicology courses of the Faculty of Pharmacy and Science, that can also be profitably utilised by students following different degree courses in other Faculties (Medicine, Agriculture, Engineering)and by anyone else looking for a thorough but succinct overview of toxicological questions. TOX covers the principal sectors of general toxicology (acute and chronic toxicity, mutagenesis, teratogenesis, carcinogenesis, reproductive toxicity, oxidative damage, epidemiological methods), specialist toxicology(dietary toxicity, tobacco smoke, pesticides, N-nitroso compounds, heterocyclic amines and aromatic amines toxicity) and environmental toxicology (environmental estrogens, PAH, heavy metals, dioxins and polychlorinated di-benzo-furans, water and air pollution).
    Keywords: Medicina ; Tossicologia ; Farmacologia ; bic Book Industry Communication::M Medicine
    Language: English
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  • 2
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    Firenze University Press
    Publication Date: 2022-06-02
    Description: The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus.
    Keywords: bic Book Industry Communication::M Medicine
    Language: English
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  • 3
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    Collège de France
    Publication Date: 2023-12-06
    Description: There is, on the one hand, life that flows from a beginning to an end, and, on the other hand, life that constitutes human singularity because it can be recounted. We may term them “biological life” and “biographical life”. Life expectancy measures the length of the former; a life story relates the richness of the latter. Only by acknowledging both can the inequality of lives be comprehended. They should be conceived of as being both distinct and connected: distinct, because the paradox of French women shows that a long life is no guarantee of a good life; connected, because the experience of African-American men stands as a reminder that a devalued life is a damaged life. This also raises the question of refugees and migrants.
    Keywords: society ; health ; public health ; sociology ; social science ; anthropology ; inequality ; life ; social inequality ; life expectancy ; lives ; inequity ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFH Illness & addiction: social aspects ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFJ Social discrimination & inequality ; bic Book Industry Communication::M Medicine
    Language: English
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  • 4
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    Firenze University Press
    Publication Date: 2022-06-02
    Description: Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases.
    Keywords: Medicina ; Biologia ; Chimica ; bic Book Industry Communication::M Medicine
    Language: English
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  • 5
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    Firenze University Press
    Publication Date: 2022-06-02
    Description: The book tells the story of the development of both knowledge and theories about the living organisms since Antiquity until the beginning of the 20th century. It also endeavours to link the advances in sciences and the events in the life of scientists with the historical and social framework within which they lived. When possible some hints have been provided about the personalities of the scientists themselves. It is especially meant both for biologists and naturalists, but an attempt has been made to make it interesting reading also for any layman with an interest in history and sciences.
    Keywords: Biologia ; Storia ; Scienze naturali ; bic Book Industry Communication::M Medicine
    Language: English
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  • 6
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    Firenze University Press
    Publication Date: 2022-06-02
    Description: This book collects together 46 papers presented at the Third Biennial Conference of i-Rec, International Group for the Diffusion of Research and Information on Post-Disaster Reconstruction. The various sections of the book cover the technical and administrative aspects of housing and other buildings after disaster. The approach to post-disaster shelter and reconstruction exemplified by this volume is fully interdisciplinary. A very wide range of perspectives is covered, including the disciplines and sub-disciplines of seismic and structural engineering, architecture, applied geography and geology, environmental psychology, paediatrics, development studies, economics, medicine and public health, management studies and political science. The volume is also intended to commemorate the 40th anniversary of the floods that severely damaged Florence in 1966 and did terrible damage to priceless art treasures.
    Keywords: Medicina ; Ingegneria ; Servizi sanitari ; Architettura ; Atti di convegno ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBG Medical equipment & techniques ; bic Book Industry Communication::M Medicine::MQ Nursing & ancillary services::MQC Nursing
    Language: English
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  • 7
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    Firenze University Press
    Publication Date: 2022-06-02
    Description: The speed at which the COVID-19 pandemic spread across the world and the need to rapidly disseminate research outcomes highlighted the crisis of the traditional publication process, drawing attention to the scarce responsiveness to the rapid advances in research and technology, and to the global problem of closed access articles. The pandemic response created an urgency, and this urgency immediately prompted virtuous trends in academic publishing: new tools for researchers and readers, easily accessible data, a reduction in publication times (still ensuring high quality standards) and, above all, a move toward more open-access publishing. Firenze University Press has been one of the first promoter of this unprecedent "new deal" in academic publishing, and actively contributed to its realization with a rapid, open, and transparent approach. Starting from March 28, 2020 the Journals published by Firenze University Press launched a series of special calls for papers concerning the multiple and multifaceted issues related to Covid-19 in a wide range of fields, including biology, chemistry, education, sociology, economics, history, and so forth.
    Keywords: covid journals ; italian research and coronavirus ; covid collection ; covid and research ; coronavirus ; coronavirus and research ; bic Book Industry Communication::M Medicine
    Language: English
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  • 8
    Publication Date: 2022-06-02
    Description: Purinergic nucleotides and nucleosides (ATP, ADP, AMP and adenosine) are essential intracellular metabolites involved in a number of cellular processes, from energy supply to protein phosphorylation. However, in the last years, several studies demonstrated their involvement in cell signalling by the activation of specific membrane receptors (P1 and P2) and their role as neurotransmitters began to be investigated. The present work was aimed to clarify the effects of purinergic neurotransmission in different cell systems by using electrophysiological techniques. Relevant results of this research include the observation that P1 and P2 receptors play a deleterious role during "in vitro" ischemia in the rat brain, and the first demonstration of P2 receptor expression and function in a line of adult human mesenchymal stem cells.
    Keywords: Chimica ; Chimica inorganica ; Fisiologia ; Metabolismo ; Acidi nucleici ; Open Access ; bic Book Industry Communication::M Medicine
    Language: English
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  • 9
    Publication Date: 2022-06-02
    Description: Gait and mobility are cardinal to maintain autonomy and independency in daily life, also for older persons. Changes in these functions might be critical in the transition towards disability and loss of autonomy during the aging process. The aim of the present work, which collects three years of research conducted between Italy and the United States, was to assess some of the main risk factors for the progressive impairment of mobility and gait in older adults living in the community. According to our results, abnormalities in the nervous and cardiovascular systems, even subtle, are associated with a subsequent worsening of these functions. These data might help to better understand the progressive development of disability in the elderly, and in the future might also have practical implications for prevention.
    Keywords: bic Book Industry Communication::M Medicine
    Language: English
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