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  • bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general  (1,117)
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  • 1
    Publication Date: 2023-12-20
    Description: This open access book relates to the III Annual Conference hosted by the Russian Federal Ministry of Education and Science in December 2016. This event has summarized, analyzed and discussed the interim results, academic outputs and scientific achievements of the Russian Federal Targeted Programme for Research and Development in priority areas of development of the Russian Scientific and Technological Complex for 2014-2020. It contains 75 selected papers from 6 areas considered priority by the Federal programme: computer science, ecology & environment sciences; energy and energy efficiency; life sciences; nanoscience & nanotechnology; and transport & communications. The chapters report the results of the 3-years research projects supported by the Programme and finalized in 2016.
    Keywords: Q1-390 ; talent management ; sensor arrays ; oil waste ; laser technology ; oil production ; dry separation technology ; automatic speech recognition ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 2
    Publication Date: 2023-12-20
    Description: Ticks are noticeable by the high diversity of pathogens they can transmit, most of them with implications in human and animal health. Ticks are arachnids, meaning that they do not share the biological and ecological features of the mosquitoes and other parasitic Diptera. The natural foci of tick-borne pathogens may be as large as a continent, or be restricted to small portions of a country, without apparently too many similar features. The life cycle of the ticks involved three developing instars. The precise relationships of ticks and their hosts, the specific seasonal pattern of activity of ticks, and the still poorly known molecular relationships between ticks and the pathogens they can transmit, make these vectors a specially fecund field of research. Importantly, extensive studies on the biological and ecological relationships of ticks and abiotic (climate and vegetation) conditions have revealed the fine-tuning of the ticks and the pathogens they transmit, together with the biological effects of host and the driving features by the climate. The studies on tick-transmitted pathogens have been on the rise in the last years. There is a growing interest in understand the somewhat complex relationships between the landscape, the climate, the vectors and the pathogens, because the concerns of spread, probably driven by subtle changes in climate and man made alterations of the landscape. Studies on Lyme borreliosis are addressing the interesting issue of the relationships between the climate, the tick activity patterns, and the selection of strains according to the reservoir availability. Furthermore, the expanding field of habitat suitability modeling has been applied with different degrees of success to evaluate and quantify the risk of disease transmission. In such exponentially growing field, revisionary books are clearly welcome additions to the bibliographical tools of researchers. It is however necessary the compilation of works devoted to explore the tip of the iceberg in the field of research. In this Research Topic, we wish to summarize and review the studies on ecology, molecular biology, and tick-host-pathogens interactions, provided to resolve the important issues of ticks and pathogens. We want not only the results obtained by newly developed molecular tools, but rigorous reviews of the most recent advances in these issues. This Topic will cover aspects of both human and animal health, with special interest on zoonoses. Aspects of the biology of the ticks, as affecting the transmission of pathogens, are of special interest in this Topic. Studies on ticks of the poorly known family Argasidae, as related to their involvement on pathogen transmission, are especially welcome. We also wish to describe the perspective of the field in the future. Finally, the presentation of ongoing original works is greatly encouraged.
    Keywords: Q1-390 ; RC109-216 ; Review Literature as Topic ; Ticks ; tick-transmitted pathogens ; Ecology ; Epidemiology ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 3
    Publication Date: 2023-12-20
    Description: The basal ganglia has received much attention over the last two decades, as it has been implicated in many neurological and psychiatric disorders. Most of this research - in both animals and humans - attempt to understand the neural and biochemical substrates of basic motor and learning processes, and how these are affected in human patients as well as animal models of brain disorders. The current volume contains research articles and reviews describing basic, pre-clinical and clinical neuroscience research of the basal ganglia written by attendees of the 11th Triennial Meeting of the International Basal Ganglia Society (IBAGS) that was held March 3-7th, 2013 at the Princess Hotel, Eilat, Israel and by researchers of the basal ganglia. Specifically, articles in this volume include research reports on the biochemistry, computational theory, anatomy and physiology of single neurons and functional circuitry of the basal ganglia networks as well as the latest data on animal models of basal ganglia dysfunction and clinical studies in human patients.
    Keywords: Q1-390 ; Subthalamic Nucleus ; dopaime ; Parkinson's disease (PD) ; human imagine studies ; animal studies ; Basal Ganglia ; computational modeling ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 4
    Publication Date: 2023-12-20
    Description: The chlamydiae are Gram-negative, obligate intracellular bacteria with a complex developmental cycle comprising a metabolically less-active, infectious stage, the elementary body (EB), and a metabolically more active stage, the reticulate body (RB). They are responsible for many acute and chronic diseases in humans and animals. In order to play a causative role in chronic diseases, chlamydiae would need to persist and to re-activate within infected cells/tissues for extended periods of time. Persistence in vitro is defined as viable but non-cultivable chlamydiae involving morphologically enlarged, aberrant, and nondividing RBs, termed aberrant bodies (AB). In vitro, alterations of the normal developmental cycle of chlamydiae can be induced by the addition of Interferon-? (IFN-?), tumor necrosis factor-a (TNF-a) and penicillin G exposure as well as amino acid or iron deprivation, monocyte infection and co-infection with viruses. In vivo, key questions include whether or not ABs occur in infected patients and animals and whether such ABs can contribute to prolonged, chronic inflammation, fibrosis, and scarring through continuing stimulation of the host immune system known from diseases such as trachoma, pelvic inflammatory disease, reactive arthritis and atherosclerosis. To date, the direct causal role in the pathogenesis of chlamydial infection and persistence in vivo has been questioned since there was no tractable animal model of chlamydial persistence so far. A very recent study was able to establish an experimental animal model of in vivo persistence, when C. muridarum vaginally-infected mice were gavaged with amoxicillin. Amoxicillin treatment induced C. muridarum to enter the persistent state in vivo. Recent in vivo data from patients indicate that viable but non-infectious developmental stages are present in the genital tract of chronically-infected women and that the gastrointestinal tract might be a reservoir for persistent chlamydial infections at other sites.
    Keywords: Q1-390 ; RC109-216 ; stress response ; chlamydia ; Chronic Disease ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Research on alternative energy harvesting technologies, conversion and storage systems with high efficiency, cost-effective and environmentally friendly systems, such as fuel cells, rechargeable metal-air batteries, unitized regenerative cells, and water electrolyzers has been stimulated by the global demand on energy. The conversion between oxygen and water plays a key step in the development of oxygen electrodes: oxygen reduction reaction (ORR) and oxygen evolution reaction (OER), processes activated mostly by precious metals, like platinum. Their scarcity, their prohibitive cost, and declining activity greatly hamper large-scale applications. This issue reports on novel non-precious metal electrocatalysts based on the innovative design in chemical compositions, structure, and morphology, and supports for the oxygen reaction.
    Keywords: Q1-390 ; QC1-999 ; n/a ; nitrogen sulfur co-doped carbon nanofibers ; layered double hydroxide ; three-dimensional ; water splitting ; non-precious metal ; metal–organic framework ; Co-bpdc/MWCNTs composites ; alkaline ; nanocarbon ; Fe-N-C catalyst ; cobalt-based electrocatalysts ; 2 ; non-precious metal catalyst ; 3 ; silver bismuthate ; 4 ; graphene-carbon nanotube aerogel ; 6-tri(2-pyridyl)-1 ; Co-bpdc ; binary nitrogen precursors ; g-C3N4 ; oxygen evolution reaction ; mesoporous NiO ; electrocatalyst ; nucleophilic attack ; 5-triazine ; cobalt and nitrogen co-doped ; fuel cells ; metal-free catalysts ; oxygen reduction reaction ; hydrogen evolution reaction ; heteroatom doping ; electrophilic Ni3+ and O? ; bacterial cellulose/poly(methylene blue) hybrids ; active site ; manganese dioxide ; electrocatalysis ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: The practical importance of economic valuation information can hardly be overstated. Coastal and marine resource policy planning and management benefit from complete information on the impact of policy decisions.
    Keywords: Q1-390 ; internet survey ; open access ; contingent valuation method ; coastal management ; tourism ; Thailand ; marine ; wetlands ; harmful algae blooms ; environmental valuation ; quota ; cyanobacteria ; estuarine and coastal ecosystems ; wealth accounting ; seawater quality ; economic analysis ; remote sensing ; ecosystem restoration ; coastal ecosystems ; random utility model ; contingent behavior ; public policy ; habitat–fishery linkages ; Barbados ; coastal ecosystem services valuation ; fishery ; mangroves ; ecosystem services valuation ; coral reefs valuation ; recreational boating ; regulated open access ; non-market value ; economic valuation ; ecosystem services ; coastal ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 7
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    Frontiers Media SA
    Publication Date: 2023-12-20
    Description: Infectious disease is the result of an interactive relationship between a microbial pathogen and its host. In this interaction both the host and the pathogen attempt to manipulate each other using a complex network to maximize their respective survival probabilities. Programmed host cell death is a direct outcome of host-pathogen interaction and may benefit host or pathogen depending on microbial pathogenesis. Apoptosis and pyroptosis are two common programmed cell death types induced by various microbial infections. Apoptosis is non-inflammatory programmed cell death and can be triggered through intrinsic or extrinsic pathways and with or without the contribution of mitochondria. Pyroptosis is an inflammatory cell death and is typically triggered by caspase-1 after its activation by various inflammasomes. However, some non-canonical caspase-1-independent proinflammatory cell death phenomena have been reported. Microbial pathogens are able to modulate host apoptosis and pyroptosis through different triggers and pathways. The promotion and inhibition of host apoptosis and pyroptosis vary and depend on the microbe types, virulence, and phenotypes. For example, virulent pathogens and attenuated vaccine strains may use different pathways to modulate host cell death. Specific microbial genes may be responsible for the modulation of host cell death. Different host cells, including macrophages, dendritic cells, and T cells, can undergo apoptosis and pyroptosis after microbial infections. The pathways of host apoptosis and pyroptosis induced by different microbes may also differ. Different methods can be used to study the interaction between microbes and host cell death system. The articles included in this E-book report the cutting edge findings in the areas of microbial modulation of host apoptosis, pyroptosis and inflammasome.
    Keywords: Q1-390 ; RC109-216 ; microbial infection ; pyroptosis ; Mycobacterium tuberculosis ; bacterial exploitation of apoptosis ; Brucella ; Infectious Disease ; Inflammasome ; Legionella ; programmed cell death ; Apoptosis ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 8
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    Les Presses de l’Université d’Ottawa | University of Ottawa Press
    Publication Date: 2023-12-20
    Description: The scientific discovery and mastery of electricity created as many important changes in modern society as did the invention of alphabetical writing in antiquity and movable type in the fifteenth century. It is more than a natural phenomenon that science has harnessed for human use; it is a central feature of the modern episteme. It has inspired writers and artists, propelled industry and innovation, and reshaped human social behaviour. Looking at a variety of topics including film, politics, and contemporary art, this volume explores the impact of electricity on knowledge, social practices, media, community life, and subjective experience.
    Keywords: Q1-390 ; innovation ; discovery ; science ; electricity ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 9
    Publication Date: 2023-12-20
    Description: The Overview of the Topic was the following: “One of the most active areas of research in molecular microbiology has been the study of how bacteria modulate their genetic activity and its consequences. The prokaryotic world has received much interest not only because the resulting phenomena are important to cells, but also because many of the effects often can be readily measured. Contributing to the interest of the present topic is the fact that modulation of gene activity involves the sensing of intra- and inter-cellular conditions, DNA binding and DNA dynamics, and interaction with the replication/transcription machinery of the cell. All of these processes are fundamental to the operation of a genetic entity and condition their lifestyle. Further, the discoveries achieved in the bacterial world have been of ample use in eukaryotes. In addition to the fundamental interest of understanding modulation of prokaryotic lifestyle by DNA-binding proteins, there is an added interest from the healthcare point of view. As it is well known the antibiotic-resistance strains of pathogenic bacteria are a major world problem, so that there is an urgent need of innovative technologies to tackle it. Most of the acquired resistances are spread by processes of horizontal gene transfer mediated by mobile elements in which DNA replication and gene expression are of basic interest. There is an imperative of finding new alternatives to the ‘classical’ way of treatment of bacterial infections and these new alternatives include the discovery of new drugs and of new bacterial targets. Nevertheless, these new alternatives will find a dead-end if we are unable to obtain a better understanding of the basic processes modulating bacterial gene expression. Our goal to achieve with this Topic of Frontiers is to accelerate our understanding of protein-DNA interactions. First, the topic will bring together several very active researchers in the study of gene replication, gene regulation, the strategies applied by the different proteins that participate in these processes, and their consequences. We will also acquire an in-depth knowledge of some of the mechanisms of gene regulation, gene transfer and gene replication. Further, the readers of the papers will realize the importance of the topic and will learn the most recent thinking, results, and approaches in the area”. We are fully confident that we have exceeded our expectations. Now we are proud to present the final output of the Topic, which is the eBook. It includes 24 articles contributed by 118 authors. As of today, Monday, 16th, January 2017, the total number of readings has reached 19,284, 14,921 article views, and 2,944 article downloads.
    Keywords: Q1-390 ; control of gene expression ; Global Regulatory Networks ; prokaryotes ; DNA replication and DNA segregation ; bacterial pathogens ; horizontal gene transfer ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 10
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: The sharing economy and collaborative consumption are attracting a great deal of interest due to their business, legal and civic implications. The consequences of the spreading of practices of sharing in urban environments and under daily dynamics are underexplored. This Special Issue aims to address if and how sharing shapes cities, the way that spaces are designed and lived in if social interactions are escalated, and the ways that habits and routines take place in post-individualistic society. In particular, the following key questions are of primary interest: Urban fabric: How is ‘sharing’ shaping cities? Does it represent a paradigm shift with tangible and physical reverberations on urban form? How are shared mobility, work, inhabiting reconfiguring the urban and social fabric? Social practices: Are new lifestyles and practices related to sharing changing the use and design of spaces? To what extent is sharing triggering a production and consumption paradigm shift to be reflected in urban arrangements and infrastructures? Sustainability: Does sharing increase the intensity of use of space and assets, or, rather, does it increase them to meet the expectations of convenience for urban lifestyles? To what extent are these phenomena fostering more economically-, socially-, and environmentally-sustainable practices and cities? Policy: How can policy makers and municipalities interact with these bottom-up and phenomena and grassroots innovation to create more sustainable cities? Scholars responded to the above questions from the fields of urban studies, urban planning and design, sociology, geography, theoretically-grounded and informed by the results of fieldwork activities.
    Keywords: Q1-390 ; Airbnb and policy innovation ; n/a ; accessibility ; Airbnb and housing typologies ; informality ; Melbourne sharing economy ; bike sharing ; local communities ; Airbnb and planning ; Airbnb and domestic design ; mobility policy ; platform cooperativism ; urban regeneration ; Airbnb and governance ; emotions ; democratic quality ; sharing ; urban studies ; stress levels ; sharing platform ; digital participation ; social relations ; spatial agency ; critical autoethnography ; cohousing ; collaborative workplaces ; participation ; Bourdieu ; co-design ; coworking ; entrepreneurial action ; coworking spaces ; Melbourne Airbnb ; coworking business ; collaborative economy ; design-research ; sustainable mobility ; urban mobility ; architecture ; architectural and urban effects of Airbnb ; ageing ; physiological sensors ; GSR ; sharing economic ; social street ; matchmaking ; socio-spatial effects of Airbnb ; sharing economy ; urban ; galvanic skin response ; coproduction ; coworking space ; emotional layer ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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