Publication Date:
2023-09-11
Description:
With the advancements in the medical and scientific fields, the global community has acquired a comprehensive understanding about brain insults and pathologies. In addition, new findings and discoveries are being made globally every day, which keep our curiosity high and drive a knowledge gain. Any brain insult or pathology is multifactorial, including a cascade of inflammation, necrotic, and apoptotic pathways; can be influenced by genetic or environmental factors; and may lead to chronic neurodegeneration or disabilities. This Special Issue, entitled “Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach”, has addressed various important aspects of brain injury and neurodegeneration, such as TBI, cerebral hypoxia, epilepsy, AD, and SARS-CoV-2-mediated brain damage. It received appreciable global response, and published 18 peer-reviewed articles, including 10 research articles and 8 reviews. Briefly, it explores the recent coronavirus infection-mediated cerebral damage; discusses the mechanism of TBI, ischemia, hypoxia, and epilepsy; talks about neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and CONDCA; and, finally, reviews the translational values of phytochemicals in brain pathologies. In conclusion, this Special Issue provides a unique review on brain injury and neurodegeneration, and will be a good tool in enhancing knowledge in terms of brain disease-related pathology, mechanisms, and translational approach.
Keywords:
neurodegenerative diseases
;
phytochemicals
;
natural products
;
neuroprotection
;
neurotrauma
;
neuroinflammation
;
excitotoxicity
;
oxidative stress
;
apoptosis
;
edema
;
brain injury
;
therapeutic strategies
;
18F-FDG PET
;
anosmia
;
COVID-19
;
SARS-CoV-2
;
olfactory dysfunction
;
anti-convulsants
;
anti-epileptic drugs
;
drug targets
;
epileptogenesis
;
non-communicable disease
;
seizures
;
transcriptional modifications
;
pseudo-resistance
;
ischemia
;
FABP3
;
FABP5
;
FABP7
;
mPGES-1
;
PGE2
;
treadmill exercise
;
Parkinson’s disease
;
neural mitochondrial functions
;
amyloid beta
;
Alzheimer’s disease
;
inflammation
;
gene regulation
;
organelle dysfunction
;
AGTPBP1
;
CCP1
;
CONDCA
;
neurodegeneration
;
NNA1
;
pcd
;
microglia
;
chronic alcoholism
;
HHV-6
;
Substantia Nigra
;
ischemic stroke
;
epigenetics
;
histone deacetylase
;
histone deacetylase inhibitor
;
mechanical stimulations
;
traumatic brain injury (TBI)
;
stretching
;
neurons
;
GSK-3β
;
p-Tau
;
extracellular matrix
;
icariin
;
icaritin
;
middle cerebral artery occlusion
;
traumatic brain injury
;
blunt-force TBI
;
post-traumatic seizures
;
zebrafish
;
sonic hedgehog signaling
;
purmorphamine
;
mild traumatic brain injury
;
microRNA
;
exomiRNA
;
exosome
;
TBI
;
tRNA
;
miRNA
;
isomiR
;
RNAseq
;
moderate traumatic brain injury
;
reactive oxygen species
;
cognitive impairment
;
mitochondria
;
hypoxia
;
neuraxis
;
hypoxic-ischemic injuries
;
neural ischemia
;
neural tissue hypoxic injuries
;
neuro-recovery
;
neurorehabilitation
;
n/a
;
bic Book Industry Communication::M Medicine
;
bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
Language:
English
Format:
application/octet-stream
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