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  • 101
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Energy is an important material basis that can promote the development of human society. Despite the increasing use of renewable energy, the overall energy supply is dominated by fossil fuels. For a long period of time, the main consumption proportion of fossil energy will not change. With the perspective of fossil fuels such as coal, oil, natural gas, shale oil, shale gas, and combustible ice, energy exploration, reservoir reconstruction, and intelligent applications in energy exploitation and energy occurrence geology are currently explored from the perspectives of exploration and exploitation technology. This reprint summarizes the intelligent unmanned mining and its development trends and conducts various research studies, including the stratigraphic correlation of sandy conglomerate in the Yellow River Delta Sag of the Bohai Bay basin, the growth and distribution of coal-measured hydrocarbon source rocks in a mixed platform, the physical and mechanical properties of sandstone, mudstone and granite in the geological environment of deep energy reservoirs, the formation mechanism of energy reservoirs and gas reservoirs, the two-phase flow experiment and numerical simulation in energy mining, the evolution law of cracks in the surrounding rock and the reinforcement principle of gradient support, and the comparison of particle pickup by axial flow and swirling flow in horizontal pneumatic conveying.
    Keywords: intelligent mine ; smart mining ; intelligent working face ; intelligent control ; adaptive ; robotic technology ; seismic rock physics ; sandstone and mudstone ; P-wave and S-wave velocity ; pressure ; temperature ; sandy conglomerate ; Huanghekou Sag ; stratigraphic correlation ; calcite U-Pb dating ; detrital zircon ; pressure-controlled pyrolysis ; oil–water separation ; centrifugal force ; two-phase vapor separation ; cyclone separation ; Tarim Basin ; mixed platform ; delta ; coal-measure distribution ; coal-measure logging response ; axial flow ; swirling flow ; pickup behavior ; coefficient of variation ; tight sandstone gas reservoir ; nuclear magnetic resonance ; fracture ; water blocking ; n/a ; rock mechanical properties ; MMTS ; geothermal development ; geothermal reservoir ; different depth of occurrence ; gas storage ; injection production simulation ; effective permeability ; seepage law ; two-dimensional simulation experiment ; fracture evolution law ; fractured seepage zone ; gradient failure support ; hierarchical control mechanism ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 102
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Robotics and control are both research and application domains that have been frequently engineered through the use of interdisciplinary approaches like cybernetics. Cognition is a particular concept of this approach, abstracted from the context of living organisms to that of artificial devices, and is concerned with knowledge acquisition and understanding through thought, experience, and the senses. Cognitive robotics and control refer to knowledge processing as much as knowledge generation from problem understanding, leading to special forms of architectures that enable systems to behave in an autonomous way. The main aim of this book is to highlight emerging applications and address recent breakthroughs in the domain of cognitive robotics and control and related areas. Procedures, algorithms, architectures, and implementations for reasoning, problem solving, or decision making are considered in the domain of robotics and control.
    Keywords: initial trajectory ; trajectory optimization ; Bézier surface ; robotics ; open FPGAs ; robot control ; surgical robotics ; human–machine interaction ; autonomous guidance ; low-cost platform ; FPGA ; S-curve ; motion control ; SoC ; telemanipulation ; haptics ; machine learning ; gesture recognition ; upper limb rehabilitation robot ; particle swam optimization (PSO) ; artificial bee colony (ABC) ; Ziegler Nichols ; Maximum sensitivity ; ontology ; robot task planning ; knowledge base ; knowledge representation ; industrial collaborative robots ; shared robotic tasks ; physical human–robot interaction ; human intention recognition ; time series classification ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 103
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 104
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: Personalised medicine is the next step in healthcare, especially when applied to genetically diverse diseases such as cancers. Naturally, a host of methods need to evolve alongside this, in order to allow the practice and implementation of individual treatment regimens. One of the major tasks for the development of personalised treatment of cancer is the identification and validation of a comprehensive, robust, and reliable panel of biomarkers that guide the clinicians to provide the best treatment to patients. This is indeed important with regards to radiotherapy; not only do biomarkers allow for the assessment of treatability, tumour response, and the radiosensitivity of healthy tissue of the treated patient. Furthermore, biomarkers should allow for the evaluation of the risks of developing adverse late effects as a result of radiotherapy such as second cancers and non-cancer effects, for example cardiovascular injury and cataract formation. Knowledge of all of these factors would allow for the development of a tailored radiation therapy regime. This Special Issue of the Journal of Personalised Medicine covers the topic of Radiation Response Biomarkers in the context of individualised cancer treatments, and offers an insight into some of the further evolution of radiation response biomarkers, their usefulness in guiding clinicians, and their application in radiation therapy.
    Keywords: carbon-ion radiotherapy ; head-and-neck tumors ; squamous cell carcinoma ; radiosensitivity ; relative biological effectiveness ; lung cancer ; radiotherapy ; radiotherapy monitoring ; radiation-induced lung injury ; RILI ; pneumonitis ; radiation-induced lung fibrosis ; RILF ; circulating biomarkers ; microRNA ; micronuclei ; uterine cervical cancer ; cGAS ; STING ; abscopal effect ; immunotherapy ; PBMCS ; micronucleus assay ; biological dosimetry ; human blood ; genotoxicity tests ; ionizing radiation ; biomarkers ; dicentric assay ; gamma H2AX foci assay ; health surveillance analyses ; clonogenic assays ; methods ; plating ; cancer ; radiation ; head and neck cancer ; exosomes ; serum ; metabolomics ; GC/MS ; biodosimetry ; chromosome aberrations ; normal tissue toxicity ; predictive tests ; normal tissue ; biomarker ; protein ; immune infiltrate ; stroma ; tumour microenvironment ; proteomics ; telomeres ; chromosomal instability ; inversions ; prostate cancer ; IMRT ; machine learning ; individual radiosensitivity ; late effects ; personalized medicine ; liquid biopsy ; circulating tumour cells ; extracellular vesicles ; microRNAs ; immune system ; inflammation ; n/a
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  • 105
    Publication Date: 2023-12-20
    Description: Landscapes have long been viewed as ‘multifunctional’, integrating ecological, economic, sociocultural, historical, and aesthetic dimensions. Landscape science and public awareness in Europe have been progressing in leaps and bounds. The challenges involved in landscape-related issues and fields, however, are multiple and refer to landscape stewardship and protection, as well as to the development of comprehensive theoretical and methodological approaches, in tandem with public sensitization and participatory governance and in coordination with appropriate top-down planning and policy instruments. Landscape-scale approaches are fundamental to the understanding of past and present cultural evolution, and are now considered to be an appropriate spatial framework for the analysis of sustainability. Methods and tools of landscape analysis and intervention have also gone a long way since their early development in Europe and the United States. Although significant progress has been made, there remain many issues which are understudied or not investigated at all—at least in a Mediterranean context. This Special Issue addresses the application of landscape theory and practice in the Eastern Mediterranean and mainly, but not exclusively, reports on the outcomes of an international conference held in Jordan, in December 2015, with the title “Landscapes of Eastern Mediterranean: Challenges, Opportunities, Prospects and Accomplishments”. The focus of this Special Issue, landscapes of the Eastern Mediterranean region, thus constitutes a timely area of research interest, not only because these landscapes have so far been understudied, but also as a rich site of strikingly variegated, long-standing multicultural human–environmental interactions. These interactions, resting on and taking shape through millennia of continuity in tradition, have been striving to adapt to technological advances, while currently juggling with manifold and multilayered socioeconomic and climate–environmental crises.
    Keywords: G1-922 ; Q1-390 ; n/a ; landscape archaeology ; Cyprus ; Landscape Character Assessment (LCA) ; Eastern Mediterranean ; Land Description Units ; stakeholders’ analysis ; UK ; local authority ; ancient sanctuaries ; East Med landscape ; Twain-born Border Lord ; Landscape Decision Support System ; mapping ; topography ; Byzantine landscape and garden art ; economy ; LCA ; classification ; churches ; Arabic-speaking ; participatory ; Landscape Risk Assessment Model ; landforms ; GIS ; planning ; typology ; Greek-speaking ; public realm ; landscape changes ; sacred space ; comparative study ; urban environment ; ideology ; political power ; Arabic landscape and garden art ; cultural sustainability ; historical maps ; religion ; rural land ; multi-functional landscapes ; Lebanon ; Mediterranean ; geographical information system ; spatial distributions ; Land Description Unit (LDU) ; political sustainability ; landscape ; landscape character assessment ; governance ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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  • 106
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In recent years, the implementation of sustainable concrete systems has been a topic of great interest in the field of construction engineering worldwide, as a result of the large and rapid increase in carbon emissions and environmental problems resulting from traditional concrete production and industry. For example, the uses of supplementary cementitious materials, geopolymer binder, recycled aggregate and industrial/agricultural wastes in concrete are all approaches to building a sustainable concrete system. However, such materials have inherent flaws due to their variety of sources, and exhibit very different properties compared with traditional concrete. Therefore, they require specific modifications in preprocessing, design, and evaluation before use in concrete. This reprint, entitled “Advances in Sustainable Concrete System”, covers a broad range of advanced concrete research in environmentally friendly concretes, cost-effective admixtures, and waste recycling, specifically including the design methods, mechanical properties, durability, microstructure, various models, hydration mechanisms, and practical applications of solid wastes in concrete systems.
    Keywords: high-strength concrete ; energy evolution ; elastic strain energy ; brittleness evaluation index ; concrete ; humidity ; moisture absorption ; moisture desorption ; numerical simulation ; acoustic emission ; AE rate process theory ; corrosion rate ; damage evolution ; axial load ; precast concrete structure ; lattice girder semi-precast slabs ; bending resistance ; FE modelling ; concrete damage ; GSP ; high strength ; hydration ; strength ; penetrability ; rice husk ash ; sustainable concrete ; artificial neural networks ; multiple linear regression ; eco-friendly concrete ; green concrete ; sustainable development ; artificial intelligence ; data science ; machine learning ; bagasse ash ; mechanical properties ; natural coarse aggregate ; recycled coarse aggregate ; two-stage concrete ; materials design ; recycled concrete ; crumb rubber concrete ; crumb rubber ; NaOH treatment ; lime treatment ; water treatment ; detergent treatment ; compressive strength ; materials ; adhesively-bonded joint ; temperature aging ; residual strength ; mechanical behavior ; failure criterion ; steel slag powder ; compound activator ; mortar strength ; orthogonal experiment ; GM (0, N) model ; ultrafine metakaolin ; silica fume ; durability ; fiber-reinforced concrete ; damage mechanism ; uniaxial tension ; cracked concrete ; crack width ; crack depth ; tortuosity ; sustainability ; concrete composites ; sulfate and acid attacks ; WPFT fibers ; coal gangue ; gradation ; cement content ; unconfined compressive strength ; freeze–thaw cycle ; minimum energy dissipation principle ; three-shear energy yield criterion ; damage variable ; constitutive model ; phosphorus slag ; limestone ; sulphate-corrosion resistance ; volume deformation ; blast furnace ferronickel slag ; alkali-activated material ; dosage of activator ; reactive powder concrete ; beam-column joint ; FE modeling ; crack ; cementitious gravel ; fly ash ; age ; optimal dosage ; bamboo ; sawdust ; pretreatment ; bio-based material ; mechanical property ; self-compacting concrete ; supplementary cementitious materials ; hydration mechanisms ; microstructure ; fresh properties ; synthetic polymer ; high temperature ; bentonite-free drilling fluid ; rheology ; filtration ; FRP reinforced concrete slab ; punching shear strength ; SHAP ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TN Civil engineering, surveying and building::TNK Building construction and materials::TNKX Conservation of buildings and building materials
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  • 107
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    European Investment Bank | European Investment Bank
    Publication Date: 2024-03-29
    Description: EU Cohesion Policy aims to strengthen economic, social and territorial cohesion across the European Union and to correct imbalances between countries and regions. The green and digital transition are key priorities of Cohesion Policy for the next years. Cohesion support 2021-2027 is focused on five key policy objectives to support growth: A more competitive and smarter Europe A greener, low-carbon transition towards a net zero carbon economy A more connected Europe by enhancing mobility A more social and inclusive Europe A Europe closer to citizens by fostering the sustainable and integrated development of all types of territories. EU funds will support investment across these policy objectives with a particular focus on a smart and green Europe. However, the COVID-19 pandemic risks deepening divergences between citizens, territories and firms. Firms across the EU will need to adapt to the post-pandemic environment and megatrends, notably digitalization and climate change, to stay competitive looking ahead. The EU has committed to a joint recovery centered on fostering the transition towards a greener and smarter economy across the EU. The extent to which this will mitigate the risks of rising inequalities and divergences across firms depends not least on support for cohesion. Data coming from the EIB Investment Survey (EIBIS) provides a unique tool to gain insights on how non-financial corporates in cohesion and non-cohesion regions are behaving. EIBIS information sheds new light on investment needs and gaps, financing requirements as well as firm activity on innovation, digitalization and climate change.
    Keywords: Political Science ; International Relations ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
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  • 108
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: In light of the considerable impact of global food supply chains on climate change, more sustainable ways of producing, distributing, and consuming food appear critical for sustainable development. With the aim of contributing to this topic, this Special Issue on sustainable food consumption and food marketing addresses various relevant issues related to food consumption, including innovative and sustainable forms of food production and consumption, animal welfare and meat consumption, price transmission, social media communication, alternative food production, and organic agriculture, among others. As such, this Special Issue sheds light on more sustainable and carbon-friendly food production and consumption systems from various angles. It delivers valuable scientific evidence for the transformation of current carbon-based food supply chains to more eco-friendly, fair, and future-oriented food supply chains.
    Keywords: aquaponics ; Structural Equation Modeling ; consumer behavior ; purchase intention ; willingness to pay ; sustainability ; food market ; veganic ; vegan-organic ; vegan ; stockless ; attitudes ; environmental marketing ; green product ; green consumer ; green purchase decision ; consumer behaviour ; theory of planned behaviour ; sustainable consumption ; Bangladesh ; out-of-home catering ; sustainable nutrition ; variety seeking ; spontaneous choice ; company canteens ; trust ; social media ; small and medium enterprises ; Bresse Gauloise ; choice experiment ; dual-purpose breeds ; faba beans ; Kollbecksmoor ; theory of planned behavior ; Vorwerkhuhn ; White Rock ; green products ; palm oil free ; structural equation modeling ; SEM ; sustainable food consumption ; food waste ; theoretical framework ; food tourism ; community-based tourism ; sustainable development ; community engagement ; rural development ; food heritage ; carbon-friendly food ; emotions ; animal welfare ; cured ham ; discrete choice experiment ; latent construct model ; market instability ; nonlinear empirical dynamics ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 109
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 110
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Cognitive building is a pioneering topic envisioning the future of our built environment. The concept of "cognitive" provides a paradigm shift that steps from the static concept of the building as a container of human activities towards the modernist vision of "machine à habiter" of Le Corbusier, where the technological content adds the capability of learning from users' behavior and environmental variables to adapt itself to achieve major goals such as user comfort, energy-saving, flexible functionality, high durability, and good maintainability. The concept is based on digital frameworks and IoT networks towards the concept of a smart city.
    Keywords: explainable post occupancy ; humanoid robot ; lighting simulation software ; BIM ; openBIM ; IFC ; IoT ; sensors ; cognitive buildings ; asset management ; digital twin ; BEM ; simulation modelling ; dynamic simulation ; Building Information Modelling (BIM) ; Internet of Things (IoT) ; facility management ; cyber-physical systems ; Building Management System ; Digital Twin ; Post-Occupancy Evaluations ; cognitive ; digital twins ; building lifecycle management ; artificial intelligence ; decision support ; self-learning ; optimization ; building performance simulation ; lighting simulation ; lighting quality ; visual comfort ; office field study ; evidence-based design ; building information modeling ; HVAC ; fan coil ; Internet of Things ; predictive maintenance ; fault detection ; smart building ; sustainable building ; construction projects ; BIM implementation ; stakeholders ; barriers ; construction product ; servitization ; level of evidence ; level curves ; ground slopes ; embankments ; road and rail design ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 111
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: This Special Issue covers current and relevant information about the applied anatomy of domestic animals, new companion animals and wild animals. It includes recent research and review articles on diverse topics based on the use of different diagnostic imaging techniques and more classic anatomical methods, providing a deeper insight into the healthy anatomy of diverse structures, which is crucial in high-quality medicine.
    Keywords: bear pelvic limb ; dog antebrachium ; horse trunk ; horse and human comparative anatomy ; magnetic resonance imaging ; anatomy ; elbow joint ; Bengal tiger (Panthera tigris tigris) ; striped dolphin (Stenella coeruleoalba) ; fetal development ; PET/SPECT/CT ; MRI ; sectional anatomy ; head anatomy ; ontogenesis ; forensics ; analysis ; Iberian wolf ; bite marks ; veterinary ; dentistry ; CT angiography ; sections ; dissections ; thorax ; neonatal foal ; computed tomography ; development ; incisor ; radiograph ; amphibians ; anurans ; sex determination ; magnetic resonance ; ultrasonography ; feline ; lower jaw ; neurovascular supply ; temporomandibular joint ; tooth ; common dolphin (Delphinus delphis) ; pilot whale (Globocephala melas) ; nose ; nasal cavity ; endoscopy ; dissection ; 3D reconstruction ; histology ; ontogeny ; mandibular fracture ; head ; Komodo dragon ; internal vertebral venous plexus ; canine ; Striped dolphin (Stenella coeruleoalba) ; Common dolphin (Delphinus delphis) ; Pilot whale (Globicephala melas) ; Risso’s dolphin (Grampus griseus) ; Harbour porpoise (Phocoena phocoena) ; mouth ; buccal ; oral ; pharyngeal ; cavity ; horse ; phalanx ; radiogrametric study ; veterinary anatomy ; n/a
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  • 112
    Publication Date: 2024-04-11
    Description: Energy systems worldwide are undergoing major transformation as a consequence of the transition towards the widespread use of clean and sustainable energy sources. Basically, this involves massive changes in technical and organizational levels together with tremendous technological upgrades in different sectors ranging from energy generation and transmission systems down to distribution systems. These actions generate huge science and engineering challenges and demands for expert knowledge in the field to create solutions for a sustainable energy system that is economically, environmentally, and socially viable while meeting high security requirements. This book covers these promising and dynamic areas of research and development, and presents contributions in sustainable energy systems planning, integration, and management. Moreover, the book elaborates on a variety of topics, ranging from design and planning of small- to large-scale energy systems to the operation and control of energy networks in different sectors, namely electricity, heat, ?and transport.
    Keywords: TA1-2040 ; T1-995 ; n/a ; Romanian coastal environment ; neural networks ; intermittent heating ; wind velocities ; time-space network ; optimal chiller loading (OCL) ; renewable energy ; pure electric buses ; mixed-integer non-linear programming problem (MINLP) ; control system ; FANP ; energy consumption ; load regulation ; energy ; smart box ; novel method ; smart logistics system ; multiple uncertainties ; non-intrusive load monitoring ; wind speed forecasting ; solid waste to energy plant ; uncertain cooling demand ; dual robust optimization ; Black Sea ; field test and numerical simulation ; electric power ; sustainable development ; multi-type bus operating organization ; cuckoo search algorithm ; vehicular emissions ; SWAN ; public transport ; product quality model ; MCDM ; TOPSIS ; heat transfer ; solar energy ; forecasting validity ; information gap decision theory (IGDT) ; photovoltaic systems ; configurations of internal wall ; ensemble empirical mode decomposition ; agricultural pruning ; hot summer and cold winter climate zone ; energy and environmental systems ; feature extraction ; information platform ; pruning biomass ; smart grid ; product usability testing ; meteorological variables ; fuzzy logic ; performance evaluation ; rural residential building ; threshold value of daily operation hours ; datacenter ; wave energy ; thermal comfort ; heat storage and release ; resampling ; risk aversion ; environment ; support vector machine ; internal coverings ; numerical models ; gradient descent ; renewable biomass energy ; demand response ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 113
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    University of New Orleans Press
    Publication Date: 2024-04-02
    Description: This volume celebrates the study of Austria in the twentieth century by historians, political scientists and social scientists produced in the previous twenty-four volumes of Contemporary Austrian Studies. One contributor from each of the previous volumes has been asked to update the state of scholarship in the field addressed in the respective volume. The title Austrian Studies Today, then, attempts to reflect the state of the art of historical and social science related studies of Austria over the past century, without claiming to be comprehensive. The volume thus covers many important themes of Austrian contemporary history and politics since the collapse of the Habsburg Monarchy in 1918―from World War I and its legacies, to the rise of authoritarian regimes in the 1930s and 1940s, to the reconstruction of republican Austria after World War II, the years of Grand Coalition governments and the Kreisky era, all the way to Austria joining the European Union in 1995 and its impact on Austria's international status and domestic politics.
    Keywords: History ; Political Science ; European Studies ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
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  • 114
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: In this reprint, state-of-the-art research and review articles on emerging material systems for additive manufacturing (AM) are collected, with a focus on the process–structure–properties relationships. Additive manufacturing (AM) has grown and evolved rapidly in recent years. There are many exciting research and translational works in many areas of application, such as biomedical, aerospace and electronics. These advancements are typically coupled with materials development, which has resulted in more functionalities added to 3D-printed parts, such as multi-material fabrications and integration with machine learning or digital twins. Such enhancements in functionalities have enabled the evolution of AM from a rapid prototyping tool to an actual manufacturing solution. In this reprint, two reviews and thirteen original research articles are included to highlight the latest development in the field of materials science for AM.
    Keywords: titanium scaffolds ; 3D printing ; pore design ; selective laser melting ; lattice structures ; torsion ; design ; additive manufacturing ; functionally gradient lattice ; torsional stiffness ; energy absorption ; failure behavior ; ferritic steel ; heat treatment ; SLM ; nuclear application ; laser powder bed fusion ; solidification crack ; hot crack ; aluminum alloy powder ; EN AW-5083 ; AA5083 ; AlSi10Mg ; powder bed fusion ; metal matrix composites ; laser powder-bed fusion ; aluminum alloys ; reinforcement ; ceramic particulates ; grain refinement ; crystallographic texture ; mechanical properties ; laser-directed energy deposition ; melt pool ; process maps ; multi-fidelity Gaussian process ; Bayesian Optimization ; uncertainty quantification ; K418 alloy ; orientation ; phase ; microhardness ; color 3D printing ; penetration depth ; chromaticity ; image-based metric ; color reproduction ; Ti-24Nb-4Zr-8Sn ; titanium alloy ; biomedical engineering ; microstructure ; X-ray diffraction ; directed energy deposition ; shape-memory alloys ; joining of metals ; elemental powders ; 3D concrete printing (3DCP) ; hybrids ; geopolymer ; frost resistance ; UV radiation ; thermal conductivity ; surface finishing ; physical vapor deposition ; composites ; recycling ; polymer-matrix composites (PMCs) ; direct ink writing ; liquid deposition modeling ; glass fibers ; stainless steel ; AISI 316L ; AISI 630 (17-4PH) ; AISI 420 ; AISI 440C ; carbon content ; online monitoring ; electron beam melting ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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  • 115
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-09
    Description: This book includes impactful chapters which present scientific concepts, frameworks, architectures and ideas on sensing technologies and machine learning techniques. These are relevant in tackling the following challenges: (i) the field readiness and use of intrusive sensor systems and devices for capturing biosignals, including EEG sensor systems, ECG sensor systems and electrodermal activity sensor systems; (ii) the quality assessment and management of sensor data; (iii) data preprocessing, noise filtering and calibration concepts for biosignals; (iv) the field readiness and use of nonintrusive sensor technologies, including visual sensors, acoustic sensors, vibration sensors and piezoelectric sensors; (v) emotion recognition using mobile phones and smartwatches; (vi) body area sensor networks for emotion and stress studies; (vii) the use of experimental datasets in emotion recognition, including dataset generation principles and concepts, quality insurance and emotion elicitation material and concepts; (viii) machine learning techniques for robust emotion recognition, including graphical models, neural network methods, deep learning methods, statistical learning and multivariate empirical mode decomposition; (ix) subject-independent emotion and stress recognition concepts and systems, including facial expression-based systems, speech-based systems, EEG-based systems, ECG-based systems, electrodermal activity-based systems, multimodal recognition systems and sensor fusion concepts and (x) emotion and stress estimation and forecasting from a nonlinear dynamical system perspective.
    Keywords: subject-dependent emotion recognition ; subject-independent emotion recognition ; electrodermal activity (EDA) ; deep learning ; convolutional neural networks ; automatic facial emotion recognition ; intensity of emotion recognition ; behavioral biometrical systems ; machine learning ; artificial intelligence ; driving stress ; electrodermal activity ; road traffic ; road types ; Viola-Jones ; facial emotion recognition ; facial expression recognition ; facial detection ; facial landmarks ; infrared thermal imaging ; homography matrix ; socially assistive robot ; EEG ; arousal detection ; valence detection ; data transformation ; normalization ; mental stress detection ; electrocardiogram ; respiration ; in-ear EEG ; emotion classification ; emotion monitoring ; elderly caring ; outpatient caring ; stress detection ; deep neural network ; convolutional neural network ; wearable sensors ; psychophysiology ; sensor data analysis ; time series analysis ; signal analysis ; similarity measures ; correlation statistics ; quantitative analysis ; benchmarking ; boredom ; emotion ; GSR ; classification ; sensor ; face landmark detection ; fully convolutional DenseNets ; skip-connections ; dilated convolutions ; emotion recognition ; physiological sensing ; multimodal sensing ; flight simulation ; activity recognition ; physiological signals ; thoracic electrical bioimpedance ; smart band ; stress recognition ; physiological signal processing ; long short-term memory recurrent neural networks ; information fusion ; pain recognition ; long-term stress ; electroencephalography ; perceived stress scale ; expert evaluation ; affective corpus ; multimodal sensors ; overload ; underload ; interest ; frustration ; cognitive load ; stress research ; affective computing ; human-computer interaction ; deep convolutional neural network ; transfer learning ; auxiliary loss ; weighted loss ; class center ; stress sensing ; smart insoles ; smart shoes ; unobtrusive sensing ; stress ; center of pressure ; regression ; signal processing ; arousal ; aging adults ; musical genres ; emotion elicitation ; dataset ; emotion representation ; feature selection ; feature extraction ; computer science ; virtual reality ; head-mounted display ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Absorbable metals have shown significant clinical potential for temporary implant applications, where the material is eventually replaced by healthy, functioning tissue. However, several challenges remain before these metals can be used in humans. Innovations and further improvements are required. This book collects scientific contributions dealing with the development of absorbable metals with improved and unique corrosion and mechanical properties for applications in highly loaded implants or cardiovascular and urethral stents.
    Keywords: surface treatments ; roughness ; Mg-alloys ; degradation behavior ; absorbable ; corrosion ; degradation ; magnesium ; ureteral stent ; zinc ; mandibular condylar fracture ; unsintered hydroxyapatite/poly-l-lactide composite plate ; bioactive resorbable plate ; biomechanical loading evaluation ; fracture fixation ; WE43/HA composite ; friction stir processing ; microstructure ; mechanical properties ; corrosion behavior ; absorbable metal ; cytotoxicity ; stent ; ureteral ; urothelial cells ; zinc alloy ; poly-L-lactide ; uncalcined and unsintered hydroxyapatite ; biocompatibility ; osteoconductivity ; mesenchymal stem cell ; iron foam ; polyethyleneimine (PEI) ; biodegradation ; powder metallurgy ; coating ; biodegradable magnesium implants ; bioceramics ; bioactivity ; orthopedic implant ; bone surgery ; absorbable implants ; magnesium (Mg) ; oral and maxillofacial ; orthopedic ; titanium (Ti) ; biomaterials ; electrochemistry ; hydrogen evolution ; microscopy ; Mg-Zn-Sn alloy ; osteoinductive activity ; sirolimus ; rabbit coronary artery endothelial cells ; smooth muscle cells ; bioabsorbable metals ; in-vivo biocompatibility ; strontium ; toxicity ; systemic reactions ; alloy accumulation ; internal organs ; iron ; corrosion rate ; biodegradable material ; n/a
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  • 117
    Publication Date: 2023-10-05
    Description: In the face of Islam's own internal struggles, it is not easy to see who we should support and how. This report provides detailed descriptions of subgroups, their stands on various issues, and what those stands may mean for the West. Since the outcomes can matter greatly to international community, that community might wish to influence them by providing support to appropriate actors. The author recommends a mixed approach of providing specific types of support to those who can influence the outcomes in desirable ways.
    Keywords: Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPS International relations ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPW Political activism::JPWL Terrorism, armed struggle
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Personalized medicine for Parkinson’s disease is a growing and emerging concept in light of recent recognition that Parkinson’s is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven “one size fits all” management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital “checklists” to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
    Keywords: Parkinson’s disease ; movement disorders ; periodontitis ; periodontal disease ; hematologic tests ; Vitamin D ; oral health ; Parkinson’s Disease ; cognition ; GABAergic signaling ; cerebellum ; MRS ; response inhibition ; non-motor symptoms ; carer stress ; older persons with Parkinson’s disease ; education ; lifestyle behaviours ; diet ; cross-sectional ; population study ; neurological disorders ; precision medicine ; genetics ; clinical trials ; Parkinson’s disease (PD) ; cognitive rehabilitation ; intervention ; deep brain stimulation ; levodopa-carbidopa intestinal gel ; apomorphine ; radiofrequency ; focused ultrasound ; induced pluripotent stem cells ; cell therapy ; gene therapy ; personalized medicine ; advanced Parkinson’s disease (APD) ; apomorphine subcutaneous infusion therapy ; pain ; intrajejunal ; levodopa ; motor and non-motor symptoms ; PKG (KinetiGrap) ; rehabilitation ; device-aided therapies ; personalised medicine ; Alzheimer’s disease ; clinical trial ; impulsive-compulsive disorders (ICD) ; dopaminergic therapy ; genetic markers ; pharmacogenetic ; polymorphisms ; insomnia ; sleep quality ; assessment ; young onset Parkinson’s (YOPD) ; Emiratis ; expatriate ; genetic ; epigenetics ; societal impact ; device aided therapies ; quality of life ; non motor symptoms ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Herein we describe some molecular aspects of the recent anti-COVID-19 research, including some approaches making use of natural remedies, especially from medicinal plants, in silico methods, and different experimental procedures that led to the discovery of novel targets of SARS-CoV-2 and consequently novel potential COVID-19 therapeutics. COVID-19 vaccines also find mention in this book with also a description of some adverse effects reported in some cases. Considering that the different beta coronaviruses present certain conserved biomolecular mechanisms and, thus, some common therapeutic targets, finding effective therapies for a specific member of their family (such as SARS-CoV, SARS-CoV-2, and MERS-CoV) even in a scenario of a reduced impact at the time of the related disease on humankind is still relevant as it could offer or inspire efficacious therapeutic strategies not only in the context of novel pathogenic mutations of the already known beta coronaviruses, but also when future zoonoses caused by other beta coronaviruses will emergence, which is not unlikely to occur in the current world where the interactions between humans and wildlife are made more and more frequent due to the growing loss of intact ecosystems worldwide.
    Keywords: coronavirus infections ; pandemics ; natural compounds ; clove ; Syzygium aromaticum ; eugenol ; eugeniin ; SARS-CoV-2 ; COVID-19 ; phytochemicals ; herbal medicine ; catechin ; polyphenol ; tea leaf extract ; theaflavin ; virucidal activity ; MERS-CoV ; S1-NTD ; pharmacophore modeling ; ADME ; quantum mechanical calculation ; DFT ; FMO ; MM/GBSA ; molecular docking ; Molecular Dynamics Simulation ; HOMO ; LUMO ; COVID-19 vaccine ; disseminated intravascular coagulation ; heparin induced thrombocytopenia ; platelet factor 4 ; thrombosis ; thrombotic thrombo-cytopenic purpura ; vaccine induced thrombocytopenia and thrombosis ; disinfectants ; ethanol ; hand hygiene ; ozonated water ; slightly acidic electrolyzed water ; virucidal mechanism ; coronavirus ; renal disease ; nephrotoxicity ; reno-protective effect ; green tea ; epigallocatechin-3-gallate (EGCG) ; flavonoids ; natural products ; medicinal plant ; SARS-Cov-2 nsp10 ; structural similarity ; fingerprint ; ADMET ; toxicity ; main protease ; triazole ; docking ; MD simulation ; drug ; proteomic ; vaccine ; immunology ; biomarker ; cheminformatics ; phytocompounds ; systems pharmacology ; anti-COVID-19 ; drug repositioning ; molecular dynamic simulations ; binding free energy ; signal peptide ; RBD protein ; secretion ; mutant ; nucleocapsid or nucleoprotein ; structure-based drug discovery ; alphafold model and molecular dynamics ; neuroinflammation ; brain fog ; neuropeptides ; neurotransmission ; metabolism ; NSAIDs ; inflammation ; ketoprofen ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: The reprint focuses on the latest research in cybersecurity and data science. Digital transformation turns data into the new oil, so the increasing availability of big data, structured and unstructured datasets, raises new challenges in cybersecurity, efficient data processing and knowledge extraction. The field of cybersecurity and data science fuels the data-driven economy. Innovations in this field require strong foundations in mathematics, statistics, machine learning and information security. The unprecedented increase in the availability of data in many fields of science and technology (e.g., genomic data, data from industrial environments, network traffic, streaming media, sensory data of smart cities, and social network data) ask for new methods and solutions for data processing, information extraction and decision support. This stimulates the development of new methods of data analysis, including those adapted to the analysis of new data structures and the growing volume of data. The papers included in this reprint discuss various topics ranging from cyberattacks, steganography, anomaly detection, evaluation of the attacker skills, modelling of the threats, and wireless security evaluation, as well as artificial intelligence, machine learning, and deep learning. Given this diversity of topics the book represents a valuable reference for researchers in cybersecurity security and data science.
    Keywords: steganography ; network security ; steganography detection ; steganalysis ; machine learning ; big data ; IoT ; pattern mining ; wireless communications ; covert channel ; dirty constellation ; wireless postmodulation steganography ; phase drift ; drift correction modulation ; undetectability ; security ; quadrature amplitude modulation ; spam ; phishing ; classification ; augmented dataset ; multi-language emails ; cybersecurity ; data protection ; SoC ; threat agents ; motivation ; opportunity ; capability ; user profiling ; implicit ; modeling ; real-time user monitoring ; complexity threat agent ; threat assessment ; network traffic analysis ; convolutional neural networks ; network traffic images ; visualization of traffic ; classifiers ; e-mail ; ham ; data science ; datasets ; cyber threats modeling ; multi-agent systems ; cyber deception ; pseudorandom sequences generators ; prime numbers ; additive Fibonacci generator ; statistical characteristics ; android device ; BrainShield ; hybrid model ; malware detection ; Omnidroid ; image processing ; BOSS database ; ensemble classifier ; deep learning ; stegomalware ; traffic analysis ; network probe ; hash function ; SHA-3 ; FPGA ; cognitive security ; cyberattacks ; game software ; threat matrix computing ; evaluation function ; data modeling ; authentication ; bit template ; information-processing electronic device ; Poisson pulse sequences generators ; n/a ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNT Media, information & communication industries::KNTX Information technology industries
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In the urological sphere, the number of tumor malignancies caused by cancer is continuously growing in Western countries. Although this is mainly due to the contemporary increase in the life expectancy of people in these geographic areas, many other factors are also contributing to this growth. Urological cancer is a complex and varied disease which affects different organs and mainly affects the male population. In fact, in most statistics, kidney, prostate, and bladder cancer are regularly included in the top-ten list of the most frequent neoplasms in males. The female population, however, has also been increasingly affected by renal and bladder cancer in the last decade. From these facts, it is clear that urological cancer is a problem of major concern in developed societies. This Topic Issue of Cancers intends to shed some light on the complexity of this field and will consider all useful and appropriate contributions from scientists and clinicians in order to improve urological cancer knowledge for patients’ benefit.
    Keywords: high-risk prostate cancer ; androgen receptor axis ; castration resistance ; neuroendocrine carcinoma ; PARP inhibition ; immunotherapy ; cancer genome ; precision targeting ; robot-assisted partial nephrectomy ; renal cell carcinoma ; indocyanine green ; nephron sparing ; prostate cancer survivors ; follow-up care ; primary health care ; general practice ; process evaluation ; Consolidated Framework for Implementation Research ; prostate-specific membrane antigen positron-emission tomography ; multiparametric magnetic-resonance imaging ; primary diagnosis ; prostate cancer ; systematic review ; diagnosis ; PSMA ; PSA ; tumor ; PET scan ; bladder cancer ; bisphenol A ; bisphenol S ; energy metabolism ; migration ; proliferation ; carbon-ion radiotherapy ; elderly patients ; radiotherapy ; particle beam therapy ; life expectancy ; systemic immune-inflammation index ; Charlson comorbidity index ; CAPRA-S ; early survival ; male incontinence ; robotic prostatectomy ; clear cell renal cell carcinoma ; ferroptosis ; prognostic model ; TCGA ; E-MTAB-1980 ; GLS2 ; pazopanib ; real-world data ; non-interventional study ; time on drug ; nivolumab ; everolimus ; trial-eligibility ; ureteral neoplasms ; urinary bladder neoplasms ; ureteroscopy ; CNTF ; CNTFRα ; LNCaP ; 22Rv1 ; castration resistant ; castration sensitive ; STAT3 ; ERK ; MMP ; biomarker ; Gleason grade ; transforming growth factor-β family ; activin ; INHBA ; INHBB ; INHBC ; prostate-specific antigen ; false-positive results ; real world-data ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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  • 122
    Publication Date: 2024-03-29
    Description: Freedom of movement (FoM) is the actual or perceived degree to which individuals or groups can move from place to place within a given environment or into and out of that environment. Focusing specifically on Afghanistan, this examination considers actual and perceived FoM for a range of groups and profiles the factors that influence them and affect data reporting in potentially misleading ways.
    Keywords: Political Science ; History ; Technology ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSH Espionage and secret services ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
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    RAND Corporation
    Publication Date: 2024-04-02
    Description: This book examines the strategic choices that American and Chinese decisionmakers face regarding sea power in the Western Pacific, shaped by geography, history, technology, and politics. In particular, the author explores the potential for cooperation on maritime security in the Western Pacific, and how the United States might pursue such cooperation as part of a broader strategy to advance its interests in the region.
    Keywords: History ; Political Science ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWC Military forces and sectors::JWCK Naval forces and warfare ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In impulse-based manufacturing technologies, the energy required to form, join or cut components acts on the workpiece in a very short time and suddenly accelerates workpiece areas to very high velocities. The correspondingly high strain rates, together with inertia effects, affect the behavior of many materials, resulting in technological benefits such as improved formability, reduced localizing and springback, extended possibilities to produce high-quality multi material joints and burr-free cutting. This Special Issue of JMMP presents the current research findings, which focus on exploiting the full potential of these processes by providing a deeper understanding of the technology and the material behavior and detailed knowledge about the sophisticated process and equipment design. The range of processes that are considered covers electromagnetic forming, electrohydraulic forming, adiabatic cutting, forming by vaporizing foil actuators and other impulse-based manufacturing technologies. Papers show significant improvements in the aforementioned processes with regard to: Processes analysis; Measurement technique; Technology development; Materials and modelling; Tools and equipment; Industrial implementation.
    Keywords: magnetic pulse welding ; spot welds ; linear coils ; shear lap test ; automotive alloys ; numerical analysis ; LS-DYNA ; impact deformation ; vaporizing foil actuator ; powder compaction ; spallation ; inclined collision welding ; dissimilar material combinations ; impact velocity ; impact angle ; collision velocity ; impulse forming ; bulge forming ; permeability ; conductivity ; adiabatic blanking ; adiabatic shear band ; high velocity ; clearance ; blanked surface ; stress triaxiality ; FE simulation ; electromagnetic forming ; proximity effect ; Lorentz forces ; coil windings ; electro-hydraulic ; pulsed forming ; numerical simulation ; preforming ; collision welding ; impact welding ; welding window ; aluminum and copper ; high-speed imaging ; jet ; cloud of particles ; energy balance ; energy extraction ; melting ; material properties ; interface morphology ; magnetic pulse welding (MPW) ; AA6016 ; aluminum ; 22MnB5 ; press-hardening steel ; interface characterization ; mechanical characterization ; tribological characterization ; high strain rate ; elevated temperature ; additive manufacturing ; 18Ni300 maraging steel ; constitutive modelling ; damage modelling ; machining simulation ; magnetic pulse forming ; electro-hydraulic forming ; high strain rates ; lightweight ; high pulsed power ; formability ; simulation ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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    African Sun Media | Sun Press
    Publication Date: 2024-03-29
    Description: At the time of his death in August 2012 Neville Alexander was undoubtedly one of South Africa’s foremost proponents of the philosophy of non-racialism. He had devoted his life to fighting against the evils of racism, sexism and economic injustice. He understood how these social realities not only divided but also ranked human beings in terms of human worth and value. He saw how these realities diminished the whole society, both the perpetrators and victims. And so he gave over his life as a scholar and a political activist to challenging these realities. This volume brings together the reflections of a group of activists and scholars on the significance of Neville Alexander to the cause of freedom and justice in South Africa. The reflections are essentially the keynote speeches and the responses to them that were made at a conference in Alexander’s honour held at the Centre for Non-Racialism and Democracy at the Nelson Mandela Metropolitan University in July 2013.
    Keywords: Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPH Political structure and processes::JPHV Political structures: democracy
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    Fordham University Press
    Publication Date: 2023-10-05
    Description: Okinawan life, at the crossroads of American militarism and Japanese capitalism, embodies a fundamental contradiction to the myth of the monoethnic state. Suspended in a state of exception, Okinawans have never been officially classified as colonial subjects of the Japanese empire or the United States, nor have they ever been treated as equal citizens of Japan. As a result, they live amid one of the densest concentrations of U.S. military bases in the world. By bringing Foucauldian biopolitics into conversation with Japanese Marxian theorizations of capitalism, Alegal uncovers Japan's determination to protect its middle class from the racialized sexual contact around its mainland bases by displacing them onto Okinawa, while simultaneously upholding Okinawa as a symbol of the infringement of Japanese sovereignty figured in terms of a patriarchal monoethnic state. This symbolism, however, has provoked ambivalence within Okinawa. In base towns that facilitated encounters between G.I.s and Okinawan women, the racial politics of the United States collided with the postcolonial politics of the Asia Pacific. Through close readings of poetry, reportage, film, and memoir on base-town life since 1945, Shimabuku traces a continuing failure to "become Japanese." What she discerns instead is a complex politics surrounding sex work, tipping with volatility along the razor's edge between insurgency and collaboration. At stake in sovereign power's attempt to secure Okinawa as a military fortress was the need to contain alegality itself-that is, a life force irreducible to the legal order. If biopolitics is the state's attempt to monopolize life, then Alegal is a story about how borderland actors reclaimed the power of life for themselves. In addition to scholars of Japan and Okinawa, this book is essential reading for anyone interested in postcolonialism, militarism, mixed-race studies, gender and sexuality, or the production of sovereignty in the modern world. Alegal is available from the publisher on an open-access basis.
    Keywords: Sociology ; History ; Asian Studies ; Political Science ; Language & Literature ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFS Social groups::JFSL Ethnic studies ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJF Asian history ; bic Book Industry Communication::H Humanities::HB History::HBT History: specific events & topics::HBTQ Colonialism & imperialism ; bic Book Industry Communication::D Literature & literary studies::DS Literature: history & criticism::DSA Literary theory
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    Publication Date: 2023-10-05
    Description: The United Kingdom Ministry of Defence's Fixed Wing Sector Strategy Board commissioned RAND Europe to assist in the development of a strategy and sustainment plan for the military fixed wing sector. RAND focused on the health and sustainment of key skills in the sector's industrial base. This monograph describes the qualitative and quantitative methodologies that the RAND team followed and summarises its findings and recommendations.
    Keywords: Political Science ; Business ; Technology ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCS Economic systems & structures ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPS International relations ; bic Book Industry Communication::T Technology, engineering, agriculture::TT Other technologies & applied sciences::TTM Military engineering
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-06-23
    Description: Virtual and augmented reality technology has seen tremendous progress in recent years, enabling novel and exciting ways to interact inside virtual environments. An interesting approach to interaction in VR and AR is the use of tangible user interfaces, which leverage on our natural understanding of the physical world and how our bodies move and interact with it, and on our learned capabilities to manipulate physical objects.For this Special Issue, we are interested in gathering research that bridges atoms and bits in virtual and augmented environments. Basic research papers that demonstrate new interaction technologies or techniques, descriptions of applications that use tangibles in VR/AR in any domain, and survey papers that can help structure and systematize current knowledge on this area are all suitable.
    Keywords: virtual reality ; haptic feedback ; tactile sensation ; sound source localization ; deaf and hard-of-hearing ; visual positioning system ; convolutional neural network ; three-dimensional object pose estimation ; voxel ; perspective-n-point ; digital taste ; galvanic taste stimulation ; taste augmentation ; mulsemedia ; taste modulation ; augmented reality ; PCNL ; simulation ; surgical rehearsal ; surgery ; immersive environment ; cognitive impairment ; physical disability ; unity ; rehabilitation ; intention prediction ; gaze-based interaction ; laparoscopic AR navigation ; liver surgery ; 3D image registration method ; point cloud registration ; collaborative robotics ; acceptability ; uncanny valley ; user experience ; extended reality ; artificial intelligence ; classification ; control ; motor rehabilitation ; prosthesis ; stroke ; surface electromyography signals ; user interface ; pseudo-haptic ; human-centered computing ; mixed and augmented reality ; game-based learning ; fantasy ; situated learning ; serious game ; embodied interaction ; data visualization ; node-link diagram ; immersive communication ; VR conference room ; panoramic live broadcast ; spatial audio ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Phytochemicals from natural products are now widely used as food additives (antioxidants, pigments), food supplements, cosmetic ingredients, etc. Currently, the majority of the extraction processes implemented on an industrial scale for the production of bioactive-enriched extracts are based on solvents of petroleum origin. However, contemporary trends in green extraction techniques dictate a minimization of solvent use, low-energy processes and novel eco-friendly materials that are environmentally benign. The search for liquids and/or extraction technologies that could meet such requirements is, therefore, an intriguing concept. This book addresses the concept of recovering natural bioactive substances from plant resources, using state-of-the-art extraction technologies, with prospects in the food, cosmetic and pharmaceutical industries.
    Keywords: cosmeceutical product ; long-lived trees ; simplex-centroid mixture design ; deep eutectic solvents ; bioactivity ; flavonoids ; extraction ; deep eutectic solvents (DES) ; natural deep eutectic solvents (NaDES) ; Moringa oleifera ; polyphenols ; ultrasonication pretreatment ; antioxidants ; hydroxypropyl β-cyclodextrin ; potato peels ; grape seed ; grape skin ; green extraction ; antioxidant activity ; chlorogenic acid ; caffeine ; β-cyclodextrin ; coffee pulp ; sensory analysis ; cold brew ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-09
    Description: The articles featured in this Special Issue cover different aspects of the design, testing, and application of various types of supplementary cementitious materials in concrete. The results of the research, conducted by over 50 international universities and scientific centers, prove the great interest in the SCM topic.
    Keywords: crystalline admixture ; chemical exposure ; sulphuric acid attack ; durability ; Xypex ; fly ash ; substitution strategy ; structural concrete ; steel reinforcement ; limit states ; RC beams in bending ; carbon footprint ; concrete ; carbonation modeling ; calcareous fly ash ; biomass ; wood ash ; fibrocement ; strength ; mortar ; clean coal combustion ; fluidized bed fly ash ; microstructure ; phase composition ; portlandite ; unburned carbon ; slag ; soil stabilization ; embankment ; cement ; lime ; high temperature ; damage ; permeability ; CEMI and CEMIII ; mechanical properties ; alkali-activated concrete ; geopolymer concrete ; flexure ; beams ; fiber-reinforced concrete ; crack spacing ; tension stiffening ; bamboo ash ; supplementary materials ; elevated temperature ; high volume fly ash (HVFA) ; steel reinforcing fiber ; jacketing ; environmental impact ; fibre reinforced ; alkali-activated ; strain hardening ; recycled cementitious supplementary material ; comprehensive concrete recycling ; recycled fine fraction ; rehydration reactivity ; compressive strength ; ground granulated blast furnace slag ; apparent activation energy ; equivalent age ; construction debris ; recycling ; circular economy ; eco-friendly concretes ; fly ash (FA) ; silica fume (SF) ; palm oil fuel ash (POFA) ; rice husk ash (RHA) ; sewage sludge ash (SSA) and sugarcane bagasse ash (SBA) ; mine tailings ; marble dust ; construction and demolition debris (CDD) ; porous feldspar ; activation ; substitute material ; energy saving concrete ; calcined clay ; binder ; supplementary cementitious materials ; cement-based materials ; steatite ; wood particles ; Portland cement ; fire performance ; tensile strength ; micro-silica/silica fume ; steel fiber ; high performance concrete (HPC) ; self-consolidating concrete (SCC) ; flowability ; freeze-thaw cycle ; fire resistance ; bentonite ; clays ; cryogenic condition ; GGBS ; thermal conductivity ; semi-adiabatic test ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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    RAND Corporation
    Publication Date: 2023-10-05
    Description: While security budgets shrink, passenger loads grow, and hostility towards security procedures increases, terrorist groups such as al Qaeda remain obsessed with attacking airplanes. In the face of these challenges and real, innovative threats, the author proposes a mechanism for conducting an independent re-examination of the strategy behind current aviation security policies and procedures—before disaster strikes.
    Keywords: Transportation Studies ; Political Science ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNG Transport industries ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPW Political activism::JPWL Terrorism, armed struggle ; bic Book Industry Communication::W Lifestyle, sport & leisure::WG Transport: general interest::WGM Aircraft: general interest
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    Springer Nature
    Publication Date: 2024-03-30
    Description: Migration; Population Economics; European Law; Political Science
    Keywords: Migration ; Population Economics ; European Law ; Political Science
    Language: English
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  • 134
    Publication Date: 2024-03-29
    Description: Deterrence of nuclear use through the threat of retaliation could be highly problematic in many plausible conflict scenarios with nuclear-armed regional adversaries. This could compel U.S. leaders to temper their military and political objectives if they come into conflict with these states. This book examines the reasons behind this important shift in the international security environment and its strategic and force planning implications.
    Keywords: Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPV Political control and freedoms
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  • 135
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: The book provides a comprehensive overview of nanostructures and methods used to design biosensors, as well as applications for these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields. Biological sensing has proven to be an essential tool for understanding living systems, but it also has practical applications in medicine, drug discovery, food safety, environmental monitoring, defense, personal security, etc. In healthcare, advancements in telecommunications, expert systems, and distributed diagnostics are challenging current delivery models, while robust industrial sensors enable new approaches to research and development. Experts from around the world have written five articles on topics including:Diagnosing and treating intraocular cancers such as retinoblastoma; Nanomedicine in cancer management; Engineered nanomaterials in osteosarcoma diagnosis and treatment; Practical design of nanoscale devices; Detect alkaline phosphatase quantitatively in clinical diagnosis; Progress in the area of non-enzymatic sensing of dual/multi biomolecules; Developments in non-enzymatic glucose and H2O2 (NEGH) sensing; Multi-functionalized nanocarrier therapies for targeting retinoblastoma; Galactose functionalized nanocarriers; Sensing performance, electro-catalytic mechanism, and morphology and design of electrode materials; Biosensors along with their applications and the benefits of machine learning; Innovative approaches to improve the NEGH sensitivity, selectivity, and stability in real-time applications; Challenges and solutions in the field of biosensors.
    Keywords: advanced nanomaterials ; dual in-line sensing ; bi-functional properties ; non-enzymatic ; electrochemical sensing ; glucose and H2O2 ; nanotechnology ; bone diseases ; drug delivery ; nanocarriers ; osteosarcoma ; tumor-targeted ; retinoblastoma ; rare cancer ; surface-tailored multi-functionalized nanoparticles ; metallic nanoparticle ; tumor-suppressor gene mutation ; alkaline phosphatase ; terminal protection ; copper nanoparticle ; fluorescence ; biosensor ; electrochemical ; sensitivity ; amperometric ; voltammetric ; food quality monitoring ; machine learning ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-08-12
    Description: Silica and silicon-based nanostructures are now well-understood materials for which the technologies are mature. The most obvious applications, such as electronic devices, have been widely explored over the last two decades. The aim of this Special Issue is to bring together the state of the art in the field and to enable the emergence of new ideas and concepts for silicon and silica-based nanostructures.
    Keywords: maize ; NPK ; SiO2-NPs ; productivity ; fertilizer ; mineral ; weevils ; LC50 ; toxicity ; mesoporous silica ; nanomaterials ; desulfurization ; fuel ; JP-8 ; black silicon ; light absorption enhanced ; micro-nano manufacturing ; nanometer surface ; nano-silica ; tricalcium aluminate ; pozzolanic reaction ; C-A-S-H gel ; silicon nanoparticles ; silicon nanowires ; synthesis ; high energy density ; lithium-ion batteries ; high-capacity anode ; VLS ; laser pyrolysis ; size effect ; shape effect ; biomass rice husk ; silicon ; nanocrystals ; luminescence ; high porosity ; pH sensor ; temperature sensor ; dual sensor ; metal-assisted chemical etching ; Si nanostructures ; high aspect ratio ; zone plate ; silicon nanowire ; nanowire array ; silicon anode ; n-type silicon anode ; Li-ion battery ; nanowires ; nanonets ; transistor ; integration process ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    transcript Verlag | transcript Verlag
    Publication Date: 2023-11-16
    Description: Brexit is a tale of two unions, not one: the British and the European unions. Their origins are different, but both struggle to maintain unity in diversity and both have to face the challenge of populism and claims of democratic deficit. Mark Corner suggests that the »four nations« that make up the UK can only survive as part of a single nation-state, if the country looks more sympathetically at the very European structures from which it has chosen to detach itself. This study addresses both academic and lay audiences interested in the current situation of the UK, particularly the strains raised by devolution and Brexit.
    Keywords: Brexit ; Constitution ; European Union ; Politics ; Europe ; Cultural History ; International Relations ; European Politics ; Democracy ; Political System ; Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPS International relations ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPS International relations::JPSN International institutions::JPSN2 EU & European institutions ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPH Political structure & processes::JPHV Political structures: democracy
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  • 138
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The intention of this Special Issue is to focus on new aspects of drug discovery, including the search for new molecular targets of various diseases, the creation of new modern methods for diagnosing diseases, the development of new test systems and kits for assessing the selectivity and effectiveness of new drugs, the study of the molecular mechanisms of biologically active compounds, the formulation of new drugs, pharmacokinetic and pharmacodynamic studies, and preclinical trials of important molecules.
    Keywords: Streptococci ; antimicrobials ; QSAR ; MD simulation ; Kunitz-type peptides ; neuroprotective activity ; sea anemones ; TRPV1 ; P2X7R ; Parkinson’s disease (PD) ; diffuse large B cell lymphoma (DLBCL) ; deep neural network ; drug discovery ; drug combination ; biomarker ; cancer severity ; cancer prognosis ; MAFB ; tumor-associated macrophages ; prostate cancer ; photodynamic therapy ; magnetic resonance imaging ; ex vivo ; anti-inflammatory substance ; N-acylhydrazone ; naphthyl-N-acylhydrazone ; LASSBio-1524 analogues ; phosphacoumarin ; azomethine ylide ; cycloaddition ; anti-cancer ; cytotoxicity ; quantum chemistry ; pravastatin ; metformin ; radiation-induced intestinal injury ; minipigs ; epithelial regeneration ; inflammation ; arylazo sulfones ; DNA binding ; DNA cleavage ; DNA photocleavage ; A375 melanoma cells ; molecular docking ; radicals ; N–S bond homolysis ; platinum(II) ; five-coordinate complexes ; glycoconjugation ; cytotoxic activity ; protein X-ray structure ; lipophilicity ; natural products ; acetylcholinesterase inhibitors ; butyrylcholinesterase inhibitors ; Alzheimer’s disease ; central nervous system ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: In this book are reported nine works related to land subsidence monitoring using remote sensing techniques. Land subsidence is a common phenomenon in many regions of the world, where it causes degradation of local ecosystems and disruption of economic activities. Its effects are more evident in densely populated areas in particular in low-lying territories such as river deltas and coastal areas where the combination of land subsidence and sea level rise increases the flooding risk. For this reason, the monitoring of ground deformations is a crucial step to obtain important information for the development of risk mitigation strategies. In the presented papers, the characteristics of land subsidence occurring in different study areas are described, and recent developments in the used methodologies for the monitoring of the ground displacements are discussed and validated also by means of ground-based data. Moreover, advantages and disadvantages of the adopted techniques are highlighted. The outcomes of these research works can provide national and local authorities with useful information for the implementation of integrated monitoring systems in the areas most affected by land subsidence.
    Keywords: land subsidence ; IPTA ; land-use ; water resource utilization ; groundwater change ; deformation ; geology ; Gävle ; InSAR ; PSI ; precise levelling ; sentinel-1 ; subsidence ; Sweden ; ALOS/PALSAR ; time series analysis ; SBAS ; hot spring water ; hydrothermal fluids ; Hakone Volcano ; satellite geodesy ; radar interferometry ; persistent scatterers ; distributed scatterers ; orbit combination ; Sentinel-1 ; cavern field ; salt deposit ; geophysical modeling ; underground gas storage ; GNSS ; ground movement ; subsidence monitoring ; integrated numerical simulation ; Dubrovnik ; satellite altimetry ; tide gauges ; vertical land motion ; DInSAR ; mining-induced tremors ; land surface deformation ; Upper Silesian Coal Basin ; Interferometry ; SNAP-StaMPS ; Ground deformation ; Po River Delta ; integrated monitoring ; time-series analysis ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 140
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Current practice involves the use of 3D surgical planning and patient-specific solutions in multiple surgical areas of expertise. Patient-specific solutions have been endorsed for several years in numerous publications due to their associated benefits around accuracy, safety, and predictability of surgical outcome. The basis of 3D surgical planning is the use of high-quality medical images (e.g., CT, MRI, or PET-scans). The translation from 3D digital planning toward surgical applications was developed hand in hand with a rise in 3D printing applications of multiple biocompatible materials. These technical aspects of medical care require engineers’ or technical physicians’ expertise for optimal safe and effective implementation in daily clinical routines.The aim and scope of this Special Issue is high-tech solutions in personalized surgery, based on 3D technology and, more specifically, bone-related surgery. Full-papers or highly innovative technical notes or (systematic) reviews that relate to innovative personalized surgery are invited. This can include optimization of imaging for 3D VSP, optimization of 3D VSP workflow and its translation toward the surgical procedure, or optimization of personalized implants or devices in relation to bone surgery.
    Keywords: maxillectomy ; guided surgery ; zygomatic implants ; digital ; 3D ; prosthetic rehabilitation ; head and neck oncology ; maxillary tumor ; maxillary reconstruction ; 3D VSP ; osteoradionecrosis ; mandible ; radiotherapy ; surgery ; computer assisted surgery ; virtual surgical planning ; fracture ; virtual reduction ; 3D printing ; patient-specific customized plate ; spine surgery ; virtual surgical planning (VSP) ; 3D-printing ; patient-specific instrumentation ; drill guides ; computer-assisted surgery ; image-guided surgery ; image-guided navigation ; pedicle screw ; lateral mass screw ; precision ; condylar resection ; unilateral condylar hyperplasia ; hemimandibular hyperplasia ; hemimandibular elongation ; cone-beam computed tomography ; panoramic radiography ; imaging ; 3D virtual surgical planning ; mandibular fractures ; mandibular condyle ; three-dimensional imaging ; classification ; diagnoses ; 3D-VSP ; CAD/CAM ; FEA ; finite element analysis ; masticatory ; muscle force ; jaw ; biomechanical ; intrinsic strength ; patient-specific ; custom ; bite force ; muscle delineation ; patient-specific implants ; orbital reconstruction ; surgical navigation ; additive manufacturing ; 4D ; motion analysis ; kinematic ; prosthesis ; TMJ ; TJR ; 3D technology ; three-dimensional ; corrective osteotomy ; osteotomies ; malunion ; patient-specific instruments ; surgical guide ; acetabular fracture ; 3D fracture analysis ; 3D gap area ; three dimensional ; three-dimensional measurements ; 3DCT ; personalized medicine ; dental osseointegrated implants ; prefabricated fibula free flap ; mandible and maxilla surgery ; surgical design and simulation ; virtual planning ; n/a ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBG Medical equipment & techniques
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    Edinburgh University Press | Edinburgh University Press
    Publication Date: 2024-04-06
    Description: A wide range of actors have publicly identified cyber stability as a key policy goal but the meaning of stability in the context of cyber policy remains vague and contested. Vague because most policymakers and experts do not define cyber stability when they use the concept. Contested because they propose measures that rely – often implicitly – on divergent understandings of cyber stability. This volume is a thorough investigation of instability within cyberspace and of cyberspace itself. Its purpose is to reconceptualise stability and instability for cyberspace, highlight their various dimensions and thereby identify relevant policy measures. This book critically examines both ‘classic’ notions associated with stability – for example, whether cyber operations can lead to unwanted escalation – as well as topics that have so far not been addressed in the existing cyber literature, such as the application of a decolonial lens to investigate Euro-American conceptualisations of stability in cyberspace.
    Keywords: Political Science ; International Relations ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
    Language: English
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  • 142
    Publication Date: 2023-10-05
    Description: Congress enacted the Terrorism Risk Insurance Act (TRIA) in 2002, in response to terrorism insurance becoming unavailable or extremely costly in the wake of the 9/11 attacks. TRIA is set to expire at the end of 2014, and Congress is considering the appropriate government role in terrorism insurance markets. This policy brief examines the potential national security implications of allowing TRIA to expire.
    Keywords: Political Science ; History ; Business ; bic Book Industry Communication::K Economics, finance, business & management::KF Finance & accounting::KFF Finance::KFFN Insurance & actuarial studies ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPW Political activism::JPWL Terrorism, armed struggle
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  • 143
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-07-14
    Description: Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, “Marine Natural Products as Anticancer Agents 2.0”, gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents.
    Keywords: Clavatadine C ; spirocyclic bromotyrosines ; cytotoxicity ; cancer selectivity ; marine compounds ; melanoma A-375 cell line ; Sarcophyton convolutum ; sarcoconvolutum A–E ; cembrenoids ; anti-angiogenesis ; bromophenols ; tube formation ; vasculogenic mimicry ; brefeldin A ; ester derivative ; chronic myelogenous leukemia ; BCR-ABL ; proliferation inhibition ; molecular modeling ; 5-O-(N-Boc-l-alanine)-renieramycin T ; Xestospongia sp. ; marine sponge ; lung cancer ; anti-cancer ; cancer stem cells ; apoptosis ; Akt ; c-Myc ; migrastatics ; cell migration ; cell invasion ; metastasis ; terpenes ; algae ; marine natural products ; mitochondrial dysfunction ; oxidative stress ; anticancer ; Sphaerococcus coronopifolius ; seaweed ; Laminaria japonica ; Laminaria japonica peptides ; cancer ; liver ; cell cycle ; porphyrin ; Isabela ; hemin ; X-ray diffraction ; NOESY NMR ; cytotoxic ; colorectal cancer ; 5-fluorouracil ; 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid ; tumor-associated macrophages ; chemoresistance ; fucoidan ; immunopotentiation ; immunomodulatory ; immunotherapy ; cancer treatment ; cytokines ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This book is a collection of recent developments, methodologies, calibration and validation techniques, and applications of thermal remote sensing data and derived products from UAV-based, aerial, and satellite remote sensing. A set of 15 papers written by a total of 70 authors was selected for this book. The published papers cover a wide range of topics, which can be classified in five groups: algorithms, calibration and validation techniques, improvements in long-term consistency in satellite LST, downscaling of LST, and LST applications and land surface emissivity research.
    Keywords: Land Surface Temperature (LST) ; satellite retrievals of LST ; LST from GOES satellites ; land surface temperature ; drones ; unmanned aerial vehicles ; thermal remote sensing ; MODIS ; Bayesian Maximum Entropy ; interpolation ; Himalaya ; air temperature ; topography ; Landsat ; split window algorithm ; TIRS ; thermal ; Landsat 8 ; stray light correction ; split-window algorithm ; single-channel algorithm ; AMSR2 ; annual cycle parameters ; random forest ; cloudy sky LST ; evapotranspiration ; data fusion ; field-scale ; machine-learning ; physical model ; Sentinel-2 ; Sentinel-3 ; Downscaling ; thermal infrared ; disaggregation ; Copernicus ; hyperspectral thermal infrared ; spectral smoothness ; temperature-emissivity separation ; sensitivity analysis ; noise ; land surface temperature (LST) ; daytime LST ; nighttime LST ; validation ; land surface emissivity (LSE) ; single channel algorithm ; radiative transfer equation ; mono window algorithm ; SURFRAD data ; GK2A ; split-window method ; BSRN ; LST ; downscaling ; LSA-SAF ; Sentinel 2 ; DEM ; spatial averaging biases ; land surface emissivity ; measurement uncertainties ; emissivity box method ; Fourier transform infrared spectrometer ; portable spectrometer ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint focuses on the position of sustainability in engineering and points to the multidimensionality of the issue. Architecture, civil and engineering issues are main themes of discussion, with special attention to research and design. Attention is focused on four thematic groups: energy (including energy harvesting), economy (including building circularity), pro-health activities, and design.
    Keywords: CFD ; mechanical ventilation ; industrial buildings ; thermal comfort ; air quality ; natural environment ; construction sector ; steel ; sustainable development ; cradle-to-gate with options ; Life Cycle Assessment ; life cycle costs ; maintenance costs ; warranty period ; number of use cycles ; building circularity assessment ; material flow model ; building circularity material passport ; building circularity calculation method ; adaption ; landscape pattern ; local microclimate ; comprehensive analysis ; morphological parameters ; space syntax ; façade configuration ; visual perception ; built heritage ; Kaunas ; cultural sustainability ; PV system ; social acceptability ; system dynamics ; CO2 emissions ; feed-in-tariffs ; subsidy policy ; water management ; housing environment quality ; multi-family settlements ; Bio-Morpheme ; greenery ; automated design ; plant selector ; sustainability ; algorithmic design ; landscape design ; BIM ; green BIM ; city breathability ; urban ventilation ; urban air quality management ; blue-green infrastructure ; integrated urban planning ; economic analysis ; marketplace regeneration ; optimisation ; spatial analysis ; urban design ; vibration ; energy harvesting ; green gardens ; multifunctionality ; plus-energy building ; thermal stack ; solar energy ; integrated design ; prefabricated rural housing ; PEST ; entropy weighted TOPSIS ; implementation potential ; Chongqing ; n/a ; urban planning ; building layout ; energy demand ; climate ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-11-17
    Description: This book focuses on the modelling and the design process of gas bearings, on the experimental validation of such models, and on their applications. In particular, recent developments about foil bearings, aerostatic bearings, porous bearings, and non-contact precision positioning systems are shown.
    Keywords: aerostatic spindle ; fluid–structure interaction ; restrictor geometrical parameters ; structural dimension ; optimal design ; bump foil gas bearing ; thermo-hydrodynamic model ; temperature field ; thermal characteristics analysis ; foil bearing ; turbo machinery ; gas bearing ; industrial application ; air-bearing ; precision positioning ; tribotronics ; rotation accuracy ; roundness ; cylindricity ; dispersion coefficient ; gas bearings ; porous materials ; rotordynamics ; force coefficients ; aerostatic journal bearings ; porous bearing ; annular-thrust bearing ; numerical simulation ; finite element method ; dynamic coefficients ; eccentricity ; tilting ; tilting velocity ; partial arc ; PCB spindles ; dynamic identification ; logarithmic decrement method ; complex exponential method ; half-power method ; damping factor identification ; rigid rotor ; modal analysis ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 147
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    Pluto Books
    Publication Date: 2024-04-14
    Description: @ is For Activism examines the transformation of politics through digital media, including digital television, online social networking and mobile computing. Joss Hands maps out how political relationships have been reconfigured and new modes of cooperation, deliberation and representation have emerged. This analysis is applied to the organisation and practice of alternative politics, showing how they have developed and embraced the new political and technological environment. Hands offers a comprehensive critical survey of existing literature, as well as an original perspective on networks and political change. He includes many case studies including the anti-war and global justice movements, peer production, user created TV and 'Twitter' activism. @ is For Activism is essential for activists and students of politics and media.
    Keywords: Computer Science ; Political Science ; thema EDItEUR::U Computing and Information Technology::UT Computer networking and communications ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPW Political activism / Political engagement
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  • 148
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: Since the conceptualization of bounded rationality, management scholars started investigating how people—managers and entrepreneurs—really make decisions within (and for) organizations. The aim of this eBook is to deeply investigate trends that have flourished within this pivotal research area in conceptual and/or empirical terms, trying to provide new insights on how managers and entrepreneurs make decisions within and for organizations. In this vein, readers that approach this eBook will be taken by hand and accompanied to the discovery of how the mind of decision makers is at the basis of organizational developments or failures. In this regard, published contributions in this eBook underline how executives and entrepreneurs must be ecologically rational, thus be aware of the negative and positive effects that biases can have depending on the context and use them at their advantage. Managerial and entrepreneurial decision-making are phenomena that cannot be detached from the environment in which executives and entrepreneurs are embedded, claiming to establish new approaches to research that looks at decision-making as an individual/group/organization-environment dialectical and multi-level phenomenon.
    Keywords: behavioral strategy ; decision-making ; core self-evaluations ; intuition ; overconfidence ; performance ; nurse manager ; time pressure ; self-leadership ; stress ; entrepreneurial decision-making ; resource-based view ; opportunity identification ; competitive advantage ; critical assessments ; managerial process ; decision making ; critical infrastructure elements ; resilience ; disruption ; indication ; data lake ; data governance ; data quality ; big data ; digital transformation ; data science ; asset management ; boundary condition ; SME entrepreneurs ; accountants ; cognitive biases ; debiasing ; clinical decision-making process ; clinical reasoning ; orthopaedics ; follow-up decision ; healthcare decision ; n/a ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJC Business strategy ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas
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  • 149
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The Special Issue aimed to bring together scientists working in various branches of control theory to discuss manufacturing control problems that include the following: enterprise control and digital ecosystem creation; the development of identification theory and methodology, and related mathematical problems; parameter, nonparametric, and structure identification and expert analysis; problems regarding selection and data analysis; control systems with an identifier; modeling in intelligent systems; simulation procedures and software; digital identification; reinforcement learning; quantum modeling; intelligent model predictive control; predictive cognitive issues; problems with software quality for complex systems; and global network resources for support processes of modeling and control.
    Keywords: decision-making ; psychic and behavioral components of activity ; action ; result of activity ; equilibrium stability ; consensus ; threshold behavior ; cognitive dissonance ; conformity ; informational control ; informational confrontation ; soft sensing ; multivariate filter ; reactive distillation ; optimal stochastic control ; path planning ; 2D random search ; interception ; external disturbances ; invariance ; block control principle ; decomposition ; high-gain factors ; sliding mode control ; sigmoid function ; Gramian method ; bilinear system process identification ; generalized Lyapunov equation ; knowledgebase ; associative search models ; wavelet analysis ; adaptive differential evolution ; evolutionary computing ; Hammerstein ; nonlinear system identification ; bilinear systems ; eigenmode decomposition ; spectral expansions ; Gramians ; observability ; controllability ; small-signal analysis ; numerical algorithm ; tokamak ; plasma equilibrium reconstruction ; linear plasma models ; identification ; state observer ; LMI ; least square technique ; deep neural network ; parametric uncertainty ; robust control ; super-stability ; regular form ; dynamic mode decomposition ; system identification ; Runge–Kutta method ; nonparametric model ; artificial neural network ; Izhikevich artificial neuron ; vestibular–ocular reflex ; control Lyapunov function ; Bayes criterion ; Haar wavelets ; loss function ; mean risk ; observable stochastic systems (OStS) ; stochastic process (StP) ; wavelet canonical expansion (WLCE) ; nonparametric identification ; dynamic system ; integral model ; Volterra equations ; smoothing cubic splines ; selection of the smoothing option ; modeling ; regularization ; inverse problems ; balanced identification ; error analysis ; one-dimensional heat equation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    RAND Corporation
    Publication Date: 2024-03-29
    Description: American geopolitical interests and the potential threats to those interests are both on the rise in East Africa. The author places the spread of militant Islamism and the development of radical Islamist networks in East Africa in the broader context of the social, economic, and political factors that have shaped the region's security environment.
    Keywords: Political Science ; Technology ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Extracellular vesicles (EVs) are particles wrapped in a lipid bilayer membrane and are naturally released from cells. This kind of cargo vessel is a nanostructure that mainly transfers lipids, proteins, various nucleic acid fragments, and metabolic components to neighboring cells or distant parts of the body through the circulatory system. EVs are of great significance to the communication mechanism between cells. This book collects feature articles to enhance our understanding of the biological characteristics of EVs and their potential applications.
    Keywords: extracellular vesicle ; precision oncology ; cancer biomarker ; prostate cancer ; drug delivery ; extracellular vesicles ; lysosome ; nanocarriers ; ultrasound ; size exclusion chromatography ; differential ultracentrifugation ; head and neck squamous cell carcinoma (HNSCC) ; exosomes ; cancer ; biomarker ; diagnostic ; therapy ; liquid biopsy ; small extracellular vesicles (sEV) ; tumor-derived exosomes (TEX) ; melanoma cell-derived exosomes (MTEX) ; proteomics ; tumor microenvironment ; biomarkers ; ectosomes ; neoplasia ; microvesicles ; small extracellular vesicles ; isolation ; purification ; size-exclusion chromatography ; ultracentrifugation ; sucrose density cushion ; lymph node ; spleen ; solid tissue ; microvesicle ; exosome ; cancer therapeutic ; drug carrier ; flow cytometry ; immunophenotyping ; swarm detection ; tumor-associated macrophages ; macrophage polarization ; mannose receptor ; HIV-1 Nef ; glioblastoma ; microRNA ; immunoprecipitation ; CD44 ; human milk ; nutrient ; microbiota ; microRNAs ; nanocommunicator ; diagnostic biomarker ; drug delivery vehicle ; personalized cancer immunotherapy ; therapeutic agents ; cell-to-cell communication ; ionising radiation ; non-targeted effects ; signalling ; imaging flow cytometry ; biomarker reservoirs ; cancer diagnostics ; disease monitoring ; large EVs ; ovarian cancer cells ; ES-2 ; OAW-42 ; adipose tissue origin mesenchymal stem cells ; n/a ; bic Book Industry Communication::M Medicine
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  • 152
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-09
    Description: Functional coatings are cost-effective means to protect substrates from wear, corrosion, erosion, tribocorrosion, high temperature and high pressure in extreme environmental conditions. These are primarily manufactured through metal/ceramic powder deposition in a subsequent layer by layer fashion on the substrate materials. In all cases, the functional coatings need to be reliable for the intended application. The emerging techniques in 3D printing/additive manufacturing can be utilized to develop high-performance functional coatings. These methods provide geometrical precision, flexibility in geometrical complexity, customization of the coating layers, and reduce the raw materials waste, keeping the manufacturing cost low while addressing many of the technical barriers of conventional coating methods. With the rapid development of cutting-edge value-added technologies in aerospace, nuclear, military, space, and energy industry, 3D printing/additive manufacturing techniques will be major advantages. Novel functional coatings and 3D printing/additive manufacturing techniques will be critical to value-added components in the future development of technologies. The book provide an overview of the recent development in coating manufacturing techniques and potential to use in high-end engineering applications.
    Keywords: metal additive manufacturing ; nickel-based alloy ; microstructure ; cooling effect ; laser cladding ; TiC ; microstructure control ; wear behavior prediction ; ductile materials ; dislocation density ; microstructure and recrystallization ; cold gas dynamic spray ; molecular dynamics ; Ti coating ; cyclic potentiodynamic polarization (CPP) test ; hysteresis loop ; wear ; additive manufacturing ; Inconel 718 ; friction ; tribocorrosion ; corrosion ; H13 steel ; thermal stress cycle ; numerical simulation ; unstable alternating thermal stress ; residual stress ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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  • 153
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint focuses on research concerning various types of nanoparticles in terms of their toxicity, removal of antibiotics, and behavior in natural environments. In addition, reviews on microplastics in the atmosphere and the possible health impacts of microplastics/nanoplastics on humans are included
    Keywords: nanomaterials ; cerium oxide nanoparticles ; wild herbs ; seed germination ; root length ; nanoplastics ; nanotoxicity ; toxicology ; plastics ; health impacts ; environmental impacts ; pollution ; artificial black carbon (aBC) ; thermal treatment ; cytotoxicity ; reactive oxygen species (ROS) ; graphene oxide ; sulfamethazine ; phototransformation ; free radicals ; nanopollution ; nano-enabled products ; engineered nanomaterials ; physicochemical properties ; aquatic environments ; microplastics ; atmosphere ; distribution ; characteristics ; toxicity ; quantitative analysis ; flow-through dissolution testing ; OECD guidelines ; environmental risk assessment ; silver nanoparticles ; zinc oxide nanoparticles ; developmental toxicity ; reactive oxidative stress ; apoptosis ; autophagy ; magnetite-halloysite composites ; magnetic sorbent materials ; fluoroquinolone antibiotic ; adsorption ; wastewater treatment ; magnetic remediation ; emerging contaminants ; ecotoxicity ; ZnO nanoparticles ; trophic transfer ; neurotoxicity ; GABAergic motor neuron ; neuron damage ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 154
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Keywords: QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 155
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Keywords: QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 156
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 157
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Shape memory alloys (SMAs), in comparison with other materials, have the exceptional ability to change their properties, structure, and functionality depending on the thermal, magnetic, and/or stress fields applied. As is well known, in recent decades, the development of SMAs has allowed innovative solutions and alternatives in biomedical applications and advanced engineering structures for aerospace and automotive industries as well as in sensor and actuation systems, among other sectors. Irrespective of this, designing and engineering using these special smart materials requires a solid background in materials science in order to consolidate their importance in these fields and to broaden their relevance for other new applications. The goal of this Special Issue is to foster the dissemination of some of the latest research devoted to these special materials from different perspectives.
    Keywords: shape memory alloys ; cyclic tests ; fatigue test ; energy dissipation ; earthquake engineering ; NiTiNb ; anisotropy ; texture ; SME ; pipe joints ; NiTi ; selective laser melting ; additive manufacturing ; lattice structure ; EBSD ; superelasticity ; metamagnetic shape memory alloys ; structural defects ; magnetocaloric effect ; mechanical damping ; martensitic transitions ; phonon softening ; resonant ultrasound spectroscopy ; laser-ultrasound ; elastic constants ; high-temperature shape memory alloys ; titanium palladium ; titanium platinum ; multi-component alloys ; medium-entropy alloys ; high-entropy alloys ; laser powder bed fusion ; density control ; structure control ; process simulation ; shape memory alloy ; Fe-Mn-Al-Ni ; cyclic heat treatment ; co-based Heusler alloy ; martensitic transformation ; metamagnetic shape memory alloy ; phase diagram ; magnetic-field-induced transition ; intermetallic ; microstructure ; differential scanning calorimetry ; X-ray diffraction ; mechanical testing ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 158
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Radiopharmaceuticals are used in the diagnosis and treatment of various diseases, especially cancer. In general, radiopharmaceuticals are either salts of radionuclides or radionuclides bound to biologically active molecules, drugs, or cells. Tremendous progress has been made in discovering, developing, and commercializing numerous radiopharmaceuticals for the imaging and therapy of cancer. Significant research is ongoing in academia and the pharmaceutical industry to develop more novel radiolabeled compounds as potential radiopharmaceuticals for unmet needs. This Special Issue aims to focus on all aspects of the design, characterization, evaluation, and development of novel radiolabeled compounds for the diagnosis and treatment of cancer and the application of new radiochemistry and methodologies for the development of novel radiolabeled compounds. Outstanding contributions presented in this Special Issue will significantly add to the field of radiopharmaceuticals.
    Keywords: positron emission tomography (PET) ; pyrazoles ; fluorine-18 ; radionuclides ; PET probes ; imaging pharmaceuticals ; hypopharyngeal cancer ; 188Re-liposome ; repeated therapy ; NGS ; microRNA ; aprepitant ; radiopharmaceuticals ; neurokinin 1 receptor antagonist ; radionuclide chelators ; kidney uptake ; cleavable linkers ; neutral endopeptidase (NEP) ; renal brush border enzymes ; prostate-specific membrane antigen (PSMA) ; cancer imaging and therapy ; somatostatin analogs ; radiolabeling ; radionuclide therapy ; imaging ; adrenergic receptor ; positron emission tomography ; radiotracer ; cholecystokinin-2 receptor ; minigastrin ; molecular imaging ; targeted radiotherapy ; lutetium-177 ; EpCAM ; radionuclide ; SPECT ; iodine ; PIB ; breast ; cancer ; PET ; target-specific biomolecules ; immunoPET imaging pharmaceuticals ; production processes ; 124I-labeled monoclonal antibodies ; radiotracers ; AAZTA ; scandium-44 ; FAP ; SA ; DPP ; PREP ; radioiodine labeling ; radioiodination ; biomolecules ; peptides ; proteins ; monoclonal antibodies ; 123,124,125,131I-labeled molecules and biomolecules ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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  • 159
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Modern materials and structures are significantly different from conventional ones. Their sizes can be orders of magnitude smaller, and their compositions are so sophisticated that traditional characteristic methods are inapplicable. Non-conventional methods are essential to tackle these issues, which must often be approached in an interdisciplinary fashion. This Special Issue is a collection of articles that shed light on these problems.
    Keywords: analytical solution ; Fourier cosine series ; vibrations ; FGM rectangular plates ; Mindlin plate theory ; phased array transducer ; transducer optimization ; beam focusing ; pulse–echo mode ; harmonic generation ; stress-free boundary ; total correction ; acoustic emission ; electrical resistance ; damage monitoring ; criticality ; natural time analysis ; nonlinear parameter ; noncontact reception ; air-coupled receiver ; aluminum samples ; corrections ; field theory ; deformation and fracture ; 7075 aluminum alloy ; electronic speckle pattern interferometry ; concrete beam ; bending ; cementitious matrix ; FRCM ; analytical model ; numerical model ; linear low-density polyethylene ; digital image correlation ; optical non-destructive testing ; speckle ; fourier scaling theorem ; gaussian filtering ; optical methods ; AlSi10Mg ; SLM ; NDE ; deep learning ; CNN ; k-fold cross validation ; non-destructive testing ; optical interferometry ; residual stress ; thermal expansion ; elasticity ; high entropy alloys ; complex concentrated alloys ; refractory metal intermetallic composites ; high entropy phases ; complex concentrated phases ; Nb silicide-based alloys ; alloy design ; biomechanics ; Achilles tendon ; beam-to-beam contact ; arbitrary cross-section ; ANCF ; lithium-ion batteries ; redox-active organic anode ; organic anode materials ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PH Physics
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  • 160
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: A collection of 18 scientific papers written in honor of Professor Karlheinz Schwarz's 80th birthday. The main topics include spectroscopy, excited states, DFT developments, results analysis, solid states, and surfaces.
    Keywords: density functional theory ; Coulomb systems ; excited states ; nodal variational principle ; DFT ; anatase TiO2(101) surface ; adsorption energy ; Bader charge ; helium atom ; screened Coulomb potential ; variational Monte Carlo method ; Lagrange mesh method ; comparison theorem ; TD-DFT ; MC-PDFT ; Lie–Clementi ; Colle–Salvetti ; OLEDs ; subphthalocyanines ; UV–visible spectra ; axial substituents ; peripheral substituents ; time-dependent DFT ; hexatetra-carbon ; electrical properties ; molecular aggregates ; singlet excitons ; triplet excitons ; TDDFT ; charge-transfer states ; charge-resonance states ; Frenkel states ; localized excitations ; diabatic states ; adiabatic states ; semiconductors ; oscillator strength ; hybrid exchange-correlation functional ; non-local potential ; statistics ; methods comparison ; benchmarking ; band gaps ; atomization energy ; DFT codes ; electronic structure calculation ; numerical accuracy and precision ; kinetic functional ; Yukawa potential ; periodic DFTB ; deMonNano ; graphene ; graphite ; benzene dimers ; deposited benzene ; supported clusters ; weighted mulliken charges ; LAPW method ; APW+lo method ; all-electron DFT ; density matrix functional embedding ; density-functional theory ; householder transformation ; He atomic basis sets ; helium dimer ; He2 potential well ; correlation energy ; complete basis set ; sigma basis set ; atomic multiplet theory ; crystal/ligand-field theory ; coordination compounds ; electronic structure ; Cu2OCl2 ; Cu2OBr2 ; Cu2OI2 ; oxyhalides ; magnetic couplings ; Néel temperature ; chemical pressure ; NMR ; machine learning ; zeolites ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNR Physical chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: This Special Issue collects original research articles discussing cutting-edge work as well as perspectives on future directions in the whole range of theoretical and practical aspects in these research areas: i) Theory of fuzzy systems and soft computing; ii) Learning procedures; iii) Decision-making applications employing fuzzy logic and soft computing.
    Keywords: fuzzy partition ; fuzzy transform ; new iterative method ; Cauchy problems ; ANFIS ; basmati rice ; image processing ; grading ; quality assessment ; fuzzy inference system ; causality ; statistics ; concept-mapping ; causal graph ; numerical methods ; systems of ordinary differential equations ; NIM ; fuzzy logics ; linear motion blur ; fuzzy deblurring ; electron beam calibration ; signal and image processing ; propagation modeling ; adaptive-network-based fuzzy system ; LoRa &amp ; LoRaWAN ; radio wave propagation ; artificial neural networks ; subtracting clustering ; dual double fuzzy semi-metric ; double fuzzy semi-metric ; fuzzy semi-metric space ; triangle inequality ; triangular norm ; eye gaze tracking ; interval type-2 fuzzy logic ; vision system ; mobile robots ; intelligent control ; ordered fuzzy number ; fuzzy relation ; preorder ; strict order ; equivalence relation ; variable neighborhood search ; experimental comparison ; statistical analysis ; traveling salesman problem ; soft computing ; modeling ; vector optimization ; methods of solution of vector problems ; optimal decision-making ; numerical realization of decision-making ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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  • 162
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    transcript Verlag
    Publication Date: 2023-11-17
    Description: How do conflicts escalate? This is one of the major questions in conflict research. To offer further answers, Richard Bösch follows a tripartite agenda: First, he develops a constructivist methodology for the study of conflict escalation embedded in a Luhmannian systems theoretical world society perspective. Bösch argues that conflicts can be observed as social systems and he looks at the process of conflict escalation by analysing communication. Second, this analysis offers two case studies: the Maidan protests in Ukraine 2013-2014 and Mali's crisis 2010-2012. Third, it gives insights on how systems theoretical research can be beneficial for Peace and Conflict Studies.
    Keywords: World Society ; Conflict Escalation ; Systems Theory ; Communication ; Conflict Research ; Politics ; Violence ; Globalization ; Conflict Studies ; International Relations ; Political Science ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GT Interdisciplinary studies::GTJ Peace studies & conflict resolution ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPS International relations ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPH Political structure & processes
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-04-04
    Description: Restrictions on academic freedom, persecution and armed conflict have forced many scholars into exile. So far, the professional trajectories of these scholars and their contributions to knowledge exchange have not been studied comprehensively. The contributors to this volume address the situations and networks of scholars in exile, the challenges they face in their host countries and the opportunities they use. These issues are highly relevant to discussions about the moral economies of higher education institutions and support programs. Although the contributions largely focus on Germany as a host country, they also offer telling examples of forced mobility in the Global South, including both contemporary and historical perspectives.
    Keywords: Exile ; Migration ; Displaced Scholars ; Knowledge Exchange ; Academic Freedom ; Science ; Politics ; Sociology of Science ; University ; Refugee Studies ; Educational Policy ; Political Science ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society ; thema EDItEUR::J Society and Social Sciences::JN Education::JNM Higher education, tertiary education ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFG Refugees and political asylum
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  • 164
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: By the late 1940s, and since then, the continuous development of dislocation theories have provided the basis for correlating the macroscopic time-dependent deformation of metals and alloys—known as creep—to the time-dependent processes taking place within the metals and alloys. High-temperature deformation and stress relaxation effects have also been explained and modeled on similar bases. The knowledge of high-temperature deformation as well as its modeling in conventional or unconventional situations is becoming clearer year by year, with new contemporary and better performing high-temperature materials being constantly produced and investigated.This book includes recent contributions covering relevant topics and materials in the field in an innovative way. In the first section, contributions are related to the general description of creep deformation, damage, and ductility, while in the second section, innovative testing techniques of creep deformation are presented. The third section deals with creep in the presence of complex loading/temperature changes and environmental effects, while the last section focuses on material microstructure–creep correlations for specific material classes. The quality and potential of specific materials and microstructures, testing conditions, and modeling as addressed by specific contributions will surely inspire scientists and technicians in their own innovative approaches and studies on creep and high-temperature deformation.
    Keywords: TA1-2040 ; T1-995 ; TN1-997 ; Larson–Miller parameter ; n/a ; visualization ; bond coat ; hydrogen ; poly-crystal ; Gibbs free energy principle ; constitutive equations ; creep damage ; DFT ; finite element method ; austenitic stainless steel ; strain rate sensitivity ; MCrAlY ; excess volume ; superalloy ; scanning electron microscopy ; creep buckling ; dislocation dynamics ; creep ; elevated temperature ; modelling ; size effect ; residual stress ; superalloy VAT 32 ; water vapor ; activation energy ; small angle neutron scattering ; superalloy VAT 36 ; metallic glass ; iron aluminides ; Gr.91 ; internal stress ; relaxation fatigue ; multiaxiality ; creep grain boundary ; grain boundary cavitation ; cavitation ; solute atom ; stress exponent ; external pressure ; P92 ; TMA ; low cycle fatigue ; nanoindentation ; high temperature ; FEM ; intrinsic ductility ; normalizing ; creep ductility ; creep rupture mechanism ; microstructural features ; simulate HAZ ; P92 steel ; glide ; ferritic–martensitic steel ; creep rupture ; cyclic softening ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 165
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Thanks to their rich chemodiversity, marine natural products represent a unique source of new bioactive metabolites. As the new leading compounds in drug discovery and development, these molecules may represent challenges for the treatment of a number of human diseases, attracting the attention of many researchers during their chemical and biological studies. This Special Issue covers all fields of drugs research in which marine natural products are involved, including their isolation and characterization, biological activities, and medicinal applications as well as synthetic approaches and their related analogues. The cover picture shows “The Nudibranch mollusk Godiva quadricolor on a sponge, reflected under the surface during the low tide. Fusaro Lagoon, Bacoli (Naples)”.
    Keywords: alginate ; Sargassum duplicatum ; okra ; antioxidant ; diabetic ; wound healing ; sulfavant ; sulfoquinovosyldiacylglycerols ; sulfoglycolipids ; mass spectrometry ; UHPLC-MS ; lipids ; cancer therapy ; gold nanoparticles ; marine products ; natural products ; photosensitizer ; purpurin 18 ; reactive oxygen species ; seaweed ; biosilica ; diatom frustule ; sustainable production ; drug delivery ; Sargassum ilicifolium ; mangosteen rind ; diabetic mice ; Aquimarina sp. ; diketopiperazine ; N-phenethylacetamide ; epithelial-mesenchymal transition (EMT) ; A549 cells ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 166
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: Complex systems have long been an integral part of modern life and can be encountered everywhere. Undertaking a comprehensive study of such systems is a challenging problem, one which is impossible to solve without the use of contemporary mathematical modeling techniques. Mathematical models form the basis for the optimal design and control of complex systems. The present reprint contains all the articles accepted and published in the Special Issue of Mathematics entitled "Control, Optimization, and Mathematical Modeling of Complex Systems". This Special Issue is focused on recent theoretical and computational studies of complex systems modeling, control, and optimization. The topics addressed in this Special Issue cover a wide range of areas, including numerical simulation in physical, social, and life sciences; the modeling and analysis of complex systems based on mathematical methods and AI/ML approaches; control problems in robotics; design optimization of complex systems, modeling in economics and social sciences; stochastic models in physics and engineering; mathematical models in material science; and high-performance computing for mathematical modeling. It is our hope that the scientific results presented in this reprint will serve as valuable sources of documentation and inspiration to those seeking to delve into complex systems modeling, control, and optimization and examine their wide-ranging applications.
    Keywords: optimal control problem ; evolutionary computation ; robotics applications ; optimal control ; Lyapunov stability ; equilibrium point ; symbolic regression ; Pontryagin’s maximum principle ; continuous-time Markov chains ; ergodicity bounds ; discrete state space ; rate of convergence ; logarithmic norm ; interval analysis ; function approximation ; global optimization ; convexity evaluation ; overestimators ; underestimators ; machine learning control ; general synthesis problem ; evolutionary algorithm ; adaptive interpolation algorithm ; interval ordinary differential equations (ODEs) ; sparse grids ; hierarchical basis ; multidimensional interpolation ; high dimensions ; molecular dynamics modeling ; randomized maximum entropy estimation ; probability density functions ; Lagrange multipliers ; Lyapunov-type problems ; implicit function ; rotation of vector field ; asymptotic efficiency ; thermokarst lakes ; forecasting ; dynamical tracking target ; ship towing system ; relative curvature ; adaptive control ; discrete velocity method ; lattice Boltzmann method ; computational fluid dynamics ; mathematical modeling ; estimation ; minimax techniques ; pareto optimization ; regression analysis ; statistical uncertainty ; proton exchange membrane ; proton electrolyte membrane ; PEM ; fuel cell ; PEMFC ; power electronic converter ; DC–DC boost converter ; model predictive control ; MPC ; self-scalable robots ; modular robots ; origami structures ; complex system ; synergistic effect ; performance indicator ; structure change ; soft robotics ; continuum mechanisms ; modeling of complex systems ; kinematic model of soft robots ; mathematical modeling of complex systems ; non-linear models ; soft robotic neck ; tendon-driven actuators ; mathematical modelling ; modelling in economics ; impact of the COVID-19 ; logistics businesses ; fractional-order virus models ; stuxnet virus ; numerical computing ; supervisory control and data acquisition systems ; computer networks ; lyapunov analysis ; image segmentation ; remote sensing ; terrain identification ; data synthesis ; transfer learning ; controllability ; observability ; stochastic linear systems in finite and infinite dimensional spaces ; stochastic singular linear systems in finite and infinite dimensional spaces ; semigroup ; evolution operator ; GE-semigroup ; GE-evolution operator ; stochastic GE-evolution operator ; feature selection ; finite normal mixtures ; moving separation of mixtures ; deep LSTM ; neural network architectures ; deep learning ; turbulent plasma ; air–sea fluxes ; n/a ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNT Media, entertainment, information and communication industries::KNTX Information technology industries ; thema EDItEUR::U Computing and Information Technology::UY Computer science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-21
    Description: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe chronic health condition that is often misunderstood or ignored by health establishments. The lack of definitive diagnostic markers to separate ME/CFS patients from the healthy population as well as from other chronic disorders is problematic for both health professionals and researchers. A consortium of Australian researchers gathered to systematically understand ME/CFS, ranging from a deep analysis of clinical and pathology data to metabolomic profiles and the investigation of mitochondrial function. From this broad collaboration, a number of compelling insights have arisen that may form the basis of specific serum, blood, and/or urinary biomarkers of ME/CFS. This Special Edition reports on a conference centred on these biomedical discoveries, with other contributions, with a translation focus for predictive markers for ME/CFS diagnosis. By supporting health professionals with developments in diagnostics for this condition, the patients and their families will hopefully benefit from an improved recognition of the biomedical underpinnings of the condition and will be better able to access the care that is urgently required. This Special Edition contains a mix of speaker submissions and other accepted manuscripts that contributed to our objective of advancing biomedical insights to enable the accurate diagnosis of ME/CFS.
    Keywords: R5-920 ; RM1-950 ; fatigue syndrome ; n/a ; work rehabilitation ; tryptophan metabolism ; substrate inhibition ; myalgic encephalomyelitis ; 3-dioxygenase ; ME (Myalgic Encephalomyelitis) ; assessment ; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) ; muscles ; hypoacetylation ; circadian rhythm ; immune system ; chronic ; CFS (Chronic Fatigue Syndrome) ; energy metabolism ; ME/CFS ; immunological ; cytokine ; bistability ; diagnosis ; biomarker ; symptoms ; kynurenine pathway ; inflammation and immunity ; metabolism ; neuro-inflammation ; pathology ; signaling ; exercise ; Epstein Barr virus ; methylhistidine ; hypothalamic–pituitary–adrenal axis ; potential biomarkers ; critical point ; inflammation ; histone deacetylation ; participatory research ; neurology ; neuroimmune ; activin ; mitochondria ; patient-driven questionnaire ; medical retirement ; machine learning ; prognosis ; gut microbiota ; post-exertional malaise ; chronic fatigue syndrome ; mathematical model ; reference intervals ; diagnostic biomarker ; indoleamine-2 ; bic Book Industry Communication::M Medicine
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  • 168
    Publication Date: 2023-04-05
    Description: This reprint includes papers from different research fields, reflecting the sectional talks presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, which took place in June 2021. The objective of the 2021 Conference was to bring together perspectives and challenges in doctoral research in a common forum and to provide a platform enabling doctoral researchers to meet and share state-of-the-art developments in their fields. It consists of 16 papers presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, in several fields such as: mechanical and industrial engineering, food science and biotechnology, electrical/electronic engineering, systems engineering and information technologies, chemistry, electrochemistry, and economic models and strategies.
    Keywords: incremental pumps ; profiling of generating tools ; helical surfaces ; Romania ; coastal area ; wind energy ; measurements ; IEC classes ; wind turbines ; mass tourism ; management model ; Constanta ; PESTEL ; Black Sea ; sustainability ; eggplant peels ; bioactive compounds ; hydrogels ; anthocyanins ; beetroot peel ; betalains ; polyphenols ; CCD-RSM ; optimal control ; metaheuristic algorithms ; evolutionary algorithms ; simulation ; ventilation on ships ; HVAC requirements ; COVID-19 ; spread the disease ; airborne transmission ; HEPA filtration ; UV disinfection ; heat recovery ; L-tryptophan ; polypyrrole ; sensor ; amino acid ; cyclic voltammetry ; chronoamperometry ; atorvastatin ; carbon nanotubes ; gold nanoparticles ; Hippophae rhamnoides L. ; carotenoids ; flavonoids ; antioxidant activity ; microencapsulation ; modulation ; electromagnetic disturbances ; electromagnetic compatibility ; military ship ; communication systems ; navigation conditions ; Danube River ; management tool ; quality function deployment ; house of quality ; enwrapping surfaces ; profiling ; geometrical methods ; tower ; wind turbine ; load ; offshore wind ; marine renewable energy ; living labs ; design thinking ; coastal zone ; integrated coastal zone management (ICZM) ; Romanian coastal zone ; Black Sea basin ; wind parameters ; historical data ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies
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  • 169
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: This reprint emphasizes the perspectives and challenges surrounding COVID-19 and obesity-related cancers, including but not limited to the risk factors of severe COVID-19 in cancer patients; the complications of COVID-19 in cancer patients; the challenges in cancer treatment and surgery; guidelines for cancer care during COVID-19; delayed diagnosis and suboptimal cancer management; the impact of COVID-19 on cancer screening, early diagnosis and cancer presentation; immune response after SARS-CoV-2 infection and vaccination in cancer patients; psychological distress among cancer survivors; telehealth in cancer care; the role of diet and nutraceuticals in the prevention of severe COVID-19 and cancer; and the effects of COVID-19 pandemic on cancer research.
    Keywords: COVID-19 ; neutropenia ; G-CSF treatment ; respiratory failure ; colorectal neoplasms ; gastrointestinal neoplasms ; immune checkpoint inhibitors ; neoplasms ; oncogenic viruses ; oncolytic virotherapy ; post-acute COVID-19 syndrome ; reactive oxygen species ; tumor escape ; SARS-CoV-2 ; thyroid cancer ; differentiated thyroid cancer ; COVID-19 severity ; inflammation ; immunity ; oxidative stress ; obesity ; SARS-Cov-2 ; oncology ; cancer screening ; clinical trials ; melanoma ; management ; pandemic ; teledermatology ; diagnostic delay ; immunotherapy ; vaccination ; lymph adenopathy ; cancer ; nutraceuticals ; supplements ; colorectal ; meta-analysis ; gynecologic oncology ; malignancy ; blood cancer ; hematologic malignancy ; leukemia ; lymphoma ; multiple myeloma ; myelodysplasia ; breast cancer ; cancer care ; screening ; surgery ; psychological distress ; cancer therapies ; immunogenicity ; safety ; vaccine hesitancy ; tumor subtype ; mortality ; intensive care unit ; medico-administrative data ; France ; n/a ; bic Book Industry Communication::M Medicine
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  • 170
    Publication Date: 2023-10-05
    Description: What can the United States learn from other militaries about how better to prepare for full-spectrum operations and deployments? The authors examine the militaries of China, France, the UK, India, and Israel to (1) identify different approaches to readiness, adaptability, and operational issues and (2) assess the ways in which units are trained both for specific and general deployments and for train, advise, and assist missions.
    Keywords: Political Science ; Business ; Technology ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPV Political control & freedoms ; bic Book Industry Communication::T Technology, engineering, agriculture::TT Other technologies & applied sciences::TTM Military engineering
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  • 171
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This book presents an interesting sample of the latest advances in optimization techniques applied to electrical power engineering. It covers a variety of topics from various fields, ranging from classical optimization such as Linear and Nonlinear Programming and Integer and Mixed-Integer Programming to the most modern methods based on bio-inspired metaheuristics. The featured papers invite readers to delve further into emerging optimization techniques and their real application to case studies such as conventional and renewable energy generation, distributed generation, transport and distribution of electrical energy, electrical machines and power electronics, network optimization, intelligent systems, advances in electric mobility, etc.
    Keywords: TA1-2040 ; T1-995 ; n/a ; Stackelberg game ; MILP ; optimal congestion threshold ; magnetic field mitigation ; simulation ; multi-objective particle swarm optimization ; virtual power plant ; internal defect ; day-ahead load forecasting ; neural network ; modular predictor ; multi-objective particle swarm optimization algorithm ; stochastic optimization ; dragonfly algorithm ; unit commitment ; metaheuristic ; multi-population method (MP) ; optimization ; tabu search ; considerable decomposition ; loss minimization ; active distribution system ; islanded microgrid ; dynamic solving framework ; feature selection ; electric energy costs ; power factor compensation ; dependability ; interactive load ; overhead ; energy internet ; evolutionary computation ; wind power ; developed grew wolf optimizer ; underground ; ETAP ; fuzzy algorithm ; electric vehicles ; Schwarz’s equation ; evolutionary algorithms ; electric power contracts ; congestion management ; optimizing-scenarios method ; building energy management system ; particle encoding method ; ringdown detection ; HOMER software ; DC optimal power flow ; prosumer ; constrained parameter estimation ; distributed generations (DGs) ; strong track filter (STF) ; transient stability ; calibration ; cost minimization ; radiance ; decentralized and collaborative optimization ; hybrid renewable energy system ; renewable energy sources ; rural electrification ; distribution network reconfiguration ; interval variables ; optimization methods ; particle swarm optimization ; hierarchical scheduling ; micro grid ; AC/DC hybrid active distribution ; consensus ; artificial bee colony ; CCHP system ; data center ; support vector machine ; affinity propagation clustering ; extended Kalman filter ; affine arithmetic ; linear discriminant analysis (LDA) ; current margins ; heterogeneous networks ; Cameroon ; hybrid method ; distributed heat-electricity energy management ; discrete wind driven optimization ; fitness function ; cross-entropy ; GenOpt ; wind energy ; demand uncertainty ; UC ; off-design performance ; genetic algorithm ; energy storage ; the biomimetic membrane computing ; power system optimization ; electric vehicle ; power architectures ; economic load dispatch problem (ELD) ; runner-root algorithm (RRA) ; Cable joint ; battery energy storage system ; load curtailment ; integration assessment ; power system unit commitment ; artificial lighting ; power flow ; hybrid membrane computing ; two-point estimation method ; low-voltage networks ; demand bidding ; non-sinusoidal circuits ; energy flow model ; power transfer distribution factors ; sustainability ; HVAC system ; voltage deviation ; street light points ; radial basis function ; energy storage system ; charging/discharging ; power systems ; intelligent scatter search ; MV/LV substation ; optimal power flow ; stochastic state estimation ; eight searching sub-regions ; chaos optimization algorithm (COA) ; mutual information theory ; inter-turn shorted-circuit fault (ISCF) ; C&I particle swarm optimization ; multiobjective optimization ; passive shielding ; sub-Saharan Africa ; micro-phasor measurement unit ; geometric algebra ; bio-inspired algorithms ; adaptive consensus algorithm ; energy management ; PCS efficiency ; multi-stakeholders ; generalized generation distribution factors ; the genetic algorithm based P system ; JAYA algorithm ; thermal probability density ; power optimization ; pumped-hydro energy storage ; smart grid ; two-stage feature selection ; piecewise linear techniques ; photovoltaic ; SOCP relaxations ; switched reluctance machine (SRM) ; optimal reactive power dispatch ; optimal operation ; controllable response ; off-grid ; active shielding ; transformer-fault diagnosis ; IEEE Std. 80-2000 ; principal component analysis ; demand response ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 172
    Publication Date: 2023-10-05
    Description: By comparing modern counterinsurgency doctrine and operations to those of 1960s, this paper tests and ultimately disproves the assumption that doctrine as written and operations as conducted are tightly linked. Ingrained organizational concepts and beliefs have a much greater influence on operations than written doctrine, and altering these beliefs will require the U.S. military to reorient itself mentally as well as physically.
    Keywords: Political Science ; Management & Organizational Behavior ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPV Political control & freedoms
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  • 173
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This Urological Cancer 2020 collection contains a set of multidisciplinary contributions to the extraordinary heterogeneity of tumor mechanisms, diagnostic approaches, and therapies of the renal, urinary tract, and prostate cancers, with the intention of offering to interested readers a representative snapshot of the status of urological research.
    Keywords: renal cell carcinoma ; iron ; macrophages ; chelation therapy ; urothelial carcinoma ; transcriptome ; microtubule ; MAP1B ; prognosis ; KLF5 ; androgen receptor ; cell proliferation ; tumorigenesis ; prostate cancer ; precision medicine ; whole genome sequencing ; optical mapping ; therapy ; prostate carcinoma ; prostate mpMRI ; machine learning ; artificial intelligence ; deep learning ; neural network ; angiogenesis ; angiogenic growth factors ; antiangiogenic therapy ; renal tumors ; prevention ; α1-adrenoceptor antagonists ; anoikis ; vascularity ; research model ; oncogenes ; tumor suppressor genes ; MR-guided ; radiotherapy ; MRgRT ; stereotactic ablative radiotherapy ; stereotactic ablative radiation therapy (SABR) ; renal cell cancer ; RCC ; online adaptive ; [68Ga]Ga-PSMA PET/CT ; dual-time point imaging ; delayed imaging ; biphasic imaging ; lesion positivity rate ; CXCL9 ; PD1 ; PD-L1 ; stage T1 NMIBC ; prostatic neoplasms/mortality ; prostatic neoplasms/epidemiology ; SEER Program ; bladder cancer ; transurethral resection ; en-bloc resection ; CPT1A ; fatty acids ; serine ; androgen response ; ROS ; oxidative stress ; DONSON ; Downstream Neighbor of SON ; biomarker ; metastatic spread ; diagnosis ; differential diagnosis ; histopathology ; immunohistochemistry ; stroma signature ; patient-derived xenografts ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 174
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Due to the intensive development of the global economy, many problems are constantly emerging connected to the safety of ships’ motion in the context of increasing marine traffic. These problems seem to be especially significant for the further development of marine transportation services, with the need to considerably increase their efficiency and reliability. One of the most commonly used approaches to ensuring safety and efficiency is the wide implementation of various automated systems for guidance and control, including such popular systems as marine autopilots, dynamic positioning systems, speed control systems, automatic routing installations, etc. This Special Issue focuses on various problems related to the analysis, design, modelling, and operation of the aforementioned systems. It covers such actual problems as tracking control, path following control, ship weather routing, course keeping control, control of autonomous underwater vehicles, ship collision avoidance. These problems are investigated using methods such as neural networks, sliding mode control, genetic algorithms, L2-gain approach, optimal damping concept, fuzzy logic and others. This Special Issue is intended to present and discuss significant contemporary problems in the areas of automatic control and the routing of marine vessels.
    Keywords: collision avoidance ; ship domain ; fuzzy inference ; collision risk ; early warning system ; marine vessel ; tracking controller ; stability ; functional ; optimal damping ; fin stabilizer ; ship turning ; heel/roll reduction ; L2-gain ; uncertainty ; non-linearity ; ship motion control ; path-following ; guidance algorithm ; nonlinear feedback ; AIS Data ; trajectory prediction ; waterway transportation ; neural networks ; autonomous navigation ; multi-joint autonomous underwater vehicle (MJ-AUV) ; 3-dimensional modeling ; LQR ; LESO ; multicriteria route planning ; genetic algorithm ; particle swarm optimization ; oceanic meteorological routing ; cooperative game theory ; supply chain management ; supply disruption ; unmanned surface vehicle ; Guidance, Navigation and Control ; course keeping ; adaptive sliding mode ; unmanned surface vehicle (USV) ; system identification ; traditional neural network ; physics-informed neural network ; zigzag test ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 175
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: The recognition of the exceptional chemical and biological properties of vanadium compounds has led, in recent decades, to extensive research exploring their chemistry, biochemistry, and medicinal chemistry. Due to the prospective application of vanadium compounds as therapeutic agents against diseases such as diabetes, cancer and those provoked by parasites and bacteria, vanadium coordination chemistry and biochemistry has been an area of extensive research. Currently, the most promising potential uses of vanadium compounds are as nutritional supplements and as anticancer agents potentiated by immunotherapy. Nevertheless, researchers from all over the world are dedicating their efforts to vanadium research related to other potential therapeutic applications of vanadium compounds and to obtain insights into their beneficial effects on health and their modes of action. This Special Issue collected research contributions focused on recent advances in vanadium chemistry, biochemistry, and medicinal chemistry. I expect that this collection will have a great impact on the future direction of vanadium research.
    Keywords: polyoxometalates ; decavanadate ; cytotoxicity ; insulin-like activity ; diabetes therapy ; vanadium biochemistry ; vanadium speciation ; vanadium ; proteins ; DNA ; fluorescence ; binding constants ; mechanism of action ; oxidovanadium(V) ; vanadium Schiff base coordination complex ; low acute toxicity ; Oxidovanadium(V) ; Schiff base ; X-ray crystallography ; DNA interaction ; 2-aminopyrimidinium ; experimental and theoretical characterization ; DFT ; docking RNA/DNA ; vitamin E ; EPR ; tocopherol ; 51V NMR ; urethane ; aerosol delivery ; lung cancer ; apoptosis ; antineoplastic ; oxidovanadium(IV) phenantrholine chrysin ; vanadium cellular uptake ; anticancer ; albumin interaction ; glycosylated flavonoid ; oxidovanadium(IV) complex ; antitumoral ; antioxidant ; cell signaling ; cancer ; anticancer agents ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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  • 176
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-08
    Description: The eight articles published in this Special Issue present original, empirical research, using various methods of data collection and analysis, in relation to topics that are pertinent to the study of Islam and Muslims in Australia. The contributors include long-serving scholars in the field, mid-career researchers, and early career researchers who represent many of Australia’s universities engaged in Islamic and Muslim studies, including the Australian National University, Charles Sturt University, Deakin University, Griffith University, and the University of Newcastle. The topics covered in this Special Issue include how Muslim Australians understand Islam (Rane et al. 2020); ethical and epistemological challenges facing Islamic and Muslim studies researchers (Mansouri 2020); Islamic studies in Australia’s university sector (Keskin and Ozalp 2021); Muslim women’s access to and participation in Australia’s mosques (Ghafournia 2020); religion, belonging and active citizenship among Muslim youth in Australia (Ozalp and Ćufurović), the responses of Muslim community organizations to Islamophobia (Cheikh Hussain 2020); Muslim ethical elites (Roose 2020); and the migration experiences of Hazara Afghans (Parkes 2020).
    Keywords: Islam in the West ; Muslim professionals ; Shari’a ; religious authority ; citizenship ; Islamic finance ; neoliberalism ; religion ; Islam ; Muslims ; Australia ; online survey ; national security ; social cohesion ; Islamophobia ; collective agency ; civil society ; Strong Structuration Theory ; Multiculturalism ; racism ; Australian Muslims ; positional practices ; Muslim migrants ; reporting/representing Islam ; epistemological bias ; social categorisation ; methodological reductionism ; migration ; identity ; lived-experience ; entrepreneurialism ; gender segregation ; mosque ; Muslim women ; religious space ; Islamic studies ; Islamic higher education ; Muslim students ; Islam in university ; Islam in Australia ; classical Islamic studies ; contemporary Islamic studies ; CSU ; ISRA ; CISAC ; Muslim youth ; Muslim youth identity ; Australian Muslim youth ; disengaged identities ; active citizenship ; youth radicalisation ; Muslim youth deradicalisation ; civic engagement ; Muslim civic engagement ; youth civic engagement ; Muslim youth in the west ; n/a ; bic Book Industry Communication::H Humanities::HR Religion & beliefs ; bic Book Industry Communication::H Humanities::HR Religion & beliefs::HRH Islam ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRP Islam
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  • 177
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-01-31
    Description: Structural mechanics is an important field of engineering. The main goal of structural mechanics is to ensure that structures are safe and durable so that catastrophic situations can be prevented, which can otherwise cause loss of life, environmental pollution and financial losses. Depending on the uses of the structure and the conditions that the structure is subjected to, special treatment may be required for the analysis. Specifically, marine structures are subjected to harsh environmental conditions due to the marine environment, which can cause several different damage mechanisms including fatigue and corrosion. This book on “Marine structures” considers a wide range of areas related to marine structures and provides a compilation of numerical and experimental studies related to “Marine structures” research.
    Keywords: TC1501-1800 ; TA1-2040 ; T1-995 ; shock loads ; n/a ; jacket structures ; protective device ; tripod support structures ; soil-pile-structure interaction ; acoustic metamaterials ; semi-active ; jacket platform ; solitons ; waves ; biofouling ; seawater piping systems ; motion response ; earthquake ; low-frequency sound ; failure mechanism ; free-surface flow ; depressed bottom ; performance prediction ; acoustic band gap ; marine growth ; uncoupled analysis ; towing resistance ; viscous fluid flow ; ice-induced vibration ; superelement ; anti-collision assessment ; peridynamics ; steel ; integrated numerical model ; fairlead position ; reliability ; cross-flow ; coupled analysis ; morphology evolution ; composites ; tuned mass damper ; towing method ; wave loading ; vortex-induced vibration ; coastal protection structures ; structural control ; vortical flow ; critical mass ratio ; flexible pipe ; stochastic modeling ; offshore wind turbine ; hydrodynamics ; high pressure ; offshore integrated meteorological mast (OIMM) ; ice-resistant cone ; sediment transport ; offshore wind ; thermomechanical ; corrosion detection
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  • 178
    Publication Date: 2023-10-05
    Description: Individuals may have to rely on themselves to protect their own health and safety--perhaps even their own lives--in the event of a terrorist attack. Even those who know how to take care of themselves in the event of a fire, tornado, or earthquake might not know what to do in case of a chemical, radiological, nuclear, or biological attack. This quick guide attempts to fill in some of these gaps by offering specific actions to take during each of these situations, as well as preparations that can be taken. These actions are appropriate regardless of the likelihood of an attack, its scale, or the current government alert level; are designed to be sensitive to potential variations; and have been defined in terms of simple rules that should be easy to follow. A reference card included at the back of the guide encapsulates the key points and can be removed for display in a prominent place.
    Keywords: Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPW Political activism::JPWL Terrorism, armed struggle
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  • 179
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    Publication Date: 2023-05-10
    Description: The management of wildlife populations and their habitats are interdisciplinary fields that encompass many scientific disciplines that also impact the lives of people. Therefore, these are truly applied sciences where human dimensions play an important role.This book highlights the importance of conducting rigorous studies to design and implement the effective management and restoration of wild populations and their habitats. A new paradigm in conservation is developing that goes beyond the boundaries of protected areas to achieve the goal of sustainable development. The 16 papers in this book, including reviews and a project report, cover a broad range of topics, exploring a diversity of subjects that are representative of current practices and novel applications.We would like to thank both the MDPI publishers and editorial staff for their support and help during the process of editing this book, in addition to the authors for their contributions.
    Keywords: road safety ; roadkill ; clustering ; growth rate ; traffic intensity ; mitigation measures ; roadkill analysis ; movement patterns ; habitat characterisation ; multiple criteria ; multi-objective ranking ; environmental awareness ; machine learning ; random forest model ; structural equation modelling ; latent class analysis ; visitor mapping ; social–ecological systems ; cultural rural landscape ; protected areas ; rewilding ; rural socioeconomics ; forest expansion ; rural to urban land conversion ; biocultural heritage ; biodiversity ; naturalness ; land-cover change ; habitat quality ; InVEST ; ecosystem-based approach and assessment ; nature-based solution ; decision-making support ; national park management ; wildlife protection ; biodiversity conservation ; policy framework ; policy formulation ; China ; agricultural management ; amphibians ; beta diversity ; community ecology ; metacommunities ; constructed wetlands ; bats ; urban ecology ; long-term monitoring ; acoustics ; city parks ; community dynamics ; conservation evaluation ; at-risk species ; golden-winged warbler ; landowner incentives ; New England cottontail ; Natural Resources Conservation Service ; U.S. Department of Agriculture ; Working Lands for Wildlife ; camera-trapping ; conservation puma ; relative integrated anthropization index ; INRA ; South American grey fox ; habitat adaptability ; habitat model ; habitat selection ; habitat suitability ; use versus availability ; Maxent ; presence points ; GPS radio-collars ; anthropogenic variables ; species distribution models ; Spermophilus citellus ; maximum entropy modeling ; species distribution modeling ; climate change refugia ; urodela ; salamandridae ; caudata ; biosphere reserve ; habitat restoration ; species management ; life project ; activity patterns ; Lepus granatensis ; population decline ; niche ; Oryctolagus cuniculus ; roadside census ; predator–prey relationships ; spatio-temporal behavior ; abundance ; distance sampling ; population density ; R package ; wildlife survey ; uncertainty ; occupancy modeling ; road ecology ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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  • 180
    Publication Date: 2024-03-29
    Description: Does the fact that the majority of Turkey's population is Muslim form a hindrance to its EU membership? According to a recent policy advice by the Netherlands Scientific Council for Government Policy (WRR), the answer is an adamant 'no'. Why is this issue of Turkish Islam relevant? After all, Turkey should not be judged by standards other than the Copenhagen criteria. The answer is that the public debate outside 'Brussels' will not be limited to these official criteria. Many people in Europe are worried about Turkey's 'Islam factor'. They believe that Muslims are (potentially violent) fundamentalists who want to establish a theocracy. By explicitly examining the role of Turkish Islam and Muslims in Turkey, the WRR wants to contribute to a well-informed European public debate on Turkey's accession. This title is available in the OAPEN Library - http://www.oapen.org.
    Keywords: Political Science ; Sociology ; Religion ; bic Book Industry Communication::J Society & social sciences::JP Politics & government ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPB Comparative politics ; bic Book Industry Communication::H Humanities::HR Religion & beliefs::HRL Aspects of religion (non-Christian)::HRLB Theology ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology ; thema EDItEUR::J Society and Social Sciences::JP Politics and government ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPB Comparative politics ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRV Aspects of religion::QRVG Theology ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology
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  • 181
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.
    Keywords: activation phenotypes ; microglia ; neuroinflammation ; immunohistochemistry ; temporal cortex ; Alzheimer’s disease ; amyloid ; amyloid β-protein (Aβ) ; mAb158 ; oligomers ; protofibrils ; amyloid aggregation ; supported lipid bilayers ; time-lapse AFM ; molecular dynamics simulation ; alzheimer’s disease ; amyloid β ; bryostatin-1 ; ECE1 ; iPS ; nELAV ; neurotoxicity ; oligomer ; protein kinase C ; α-secretase ; APP mutation ; recessive inheritance ; familial Alzheimer’s disease ; Aβ oligomers ; amyloid imaging ; microbiota ; bacterial amyloid ; FUBA ; curli ; CsgA ; amyloid beta ; oxidative stress ; supplement ; phosphodiesterase III inhibitor ; cerebral micro-hemorrhage(s) ; cerebral amyloid angiopathy ; amyloid-β protein ; transgenic mice ; NMR ; CD ; Aβ ; β-amyloid peptide ; α/β-discordant ; Dutch-type mutation ; E22Q ; FAD ; Amyloid β ; Polyphenol ; Pro-oxidant ; Alzheimer’s Disease ; molecular imaging ; amyloid β-peptides ; islet amyloid polypeptide ; high-speed atomic force microscopy ; amyloid PET ; tau PET ; amyloid precursor protein ; mutation ; cerebellum ; PBB3 ; PiB ; axon ; traditional medicines ; Polygalae Radix ; diosgenin ; naringenin ; kihito ; amyloid-β ; antimicrobial ; antiviral ; antimicrobial peptide ; neurodegenerative disease ; misfolding ; fluorescence microscopy ; FRET ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 182
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    Berghahn Books | Berghahn Books
    Publication Date: 2024-04-02
    Description: Even leaving aside the vast death and suffering that it wrought on indigenous populations, German ambitions to transform Southwest Africa in the early part of the twentieth century were futile for most. For years colonists wrestled ocean waters, desert landscapes, and widespread aridity as they tried to reach inland in their effort of turning outwardly barren lands into a profitable settler colony. In his innovative environmental history, Martin Kalb outlines the development of the colony up to World War I, deconstructing the common settler narrative, all to reveal the importance of natural forces and the Kaisereich’s everyday violence.
    Keywords: History ; Africa ; West ; Political Science ; Colonialism & Post-colonialism ; Nature ; thema EDItEUR::N History and Archaeology::NH History::NHH African history ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTQ Colonialism and imperialism ; thema EDItEUR::W Lifestyle, Hobbies and Leisure::WN Nature and the natural world: general interest
    Language: English
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  • 183
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: In this book, the performance of homogeneous and heterogeneous catalysts applied in biomass processing was assessed, paying special attention to the main advantages and challenges related to their use. Indeed, these challenges are opportunities to develop new research lines that could be fruitful in the near future. Thus, different studies are included, dealing with diverse subjects, with one main goal in common: the improvement of different aspects related to biomass processing through the use of catalysts.
    Keywords: nanospheroids ; zinc-doped CaO ; natural triglycerides ; aminolysis ; heterogeneous catalyst ; recyclability ; catalyst ; sodium hydroxide ; fatty acid methyl ester ; central composite rotatable design ; operational conditions ; aerated irrigation ; soil enzyme activity ; soil microbial biomass ; soil respiration ; bio-derived phenol ; Ni-Cu-Co/Al2O3 ; in-situ hydrodeoxygenation ; cyclohexane ; hydrogenolysis ; biomass ; 5-hydroxymethylfurfural ; 2,5-furandicrboxylic acid ; aerobic oxidation ; metal catalysts ; acid catalysis ; biodiesel ; biofuel ; esterification ; fatty acid ; methanolysis ; molybdenum oxide ; transesterification ; vegetable oil ; fatty acid methyl esters ; 2-ethyl-1-hexanol ; 1-heptanol ; 4-methyl-2-pentanol ; viscosity ; flash and combustion points ; methyl oleate ; methyl ricinoleate ; cellulase ; cellulose ; paper sludge ; Saccharomyces cerevisiae ; synergism ; furfural ; carbon-supported catalyst ; xylose conversion ; iron ; heterogeneous catalysts ; thermoset polymer ; epoxy ; cellulose nanofiber ; curing characteristics ; thermal properties ; mechanical properties ; RSM ; numerical optimization ; keratinase ; feather ; Bacillus sp. ; amino acids ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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    Duncker & Humblot
    Publication Date: 2024-03-30
    Description: This volume represents some of the Proceedings of the Annual Meeting of the Research Committee on Development Economics (Ausschuss für Entwicklungsländer) of the German Economic Association (Verein für Socialpolitik) held in Cologne, Germany, in July 2004. The meeting focused on the effectiveness of, and new approaches in, development cooperation. Both issues have become increasingly important in recent years in view of the declining volume of budget funds allocated to development cooperation. The papers discussing the effectiveness of foreign aid shed new light on the issue at a crucial moment where economists have begun to question the recent consensus that the productivity of aid mainly depends on the recipient country's policy environment. As far as the contributions dealing with new approaches in development cooperation are concerned, these are centred on a closer integration of the private sector, by joint action with so-called lead firms in production networks on the one hand, and the mobilization of additional financial resources from international capital markets for bilateral development cooperation, on the other. The authors also make suggestions concerning critical aspects relevant for implementation. The last part of this volume is dedicated to an assessment of low-income countries' pension schemes based on the human capital approach.This volume represents some of the Proceedings of the Annual Meeting of the Research Committee on Development Economics (Ausschuss für Entwicklungsländer) of the German Economic Association (Verein für Socialpolitik) held in Cologne, Germany, in July 2004. The meeting focused on the effectiveness of, and new approaches in, development cooperation. Both issues have become increasingly important in recent years in view of the declining volume of budget funds allocated to development cooperation. The papers discussing the effectiveness of foreign aid shed new light on the issue at a crucial moment where economists have begun to question the recent consensus that the productivity of aid mainly depends on the recipient country's policy environment. As far as the contributions dealing with new approaches in development cooperation are concerned, these are centred on a closer integration of the private sector, by joint action with so-called lead firms in production networks on the one hand, and the mobilization of additional financial resources from international capital markets for bilateral development cooperation, on the other. The authors also make suggestions concerning critical aspects relevant for implementation. The last part of this volume is dedicated to an assessment of low-income countries' pension schemes based on the human capital approach.
    Keywords: Business ; Political Science ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJK International business ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCP Political economy
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  • 185
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-11-30
    Description: Copper-based catalysts possess important applications in diverse reactions and have received considerable attention from material and catalysis researchers. A great challenge in this field is the facile synthesis of copper-based catalysts with enhanced catalytic activity, selectivity, and durability. This Special Issue of Catalysts, entitled “Synthesis and Applications of Copper-based Catalysts”, presents state-of-the-art synthetic strategies for copper-based catalysts, as well as information on their structure and catalytic use in heterogeneous and homogeneous catalysis, which is helpful for developing novel high-efficiency Cu-based catalysts and synthetic methodology, and for exploring their new catalytic applications.
    Keywords: metal-organic frameworks ; Cu2O ; styrene oxidation ; H2O2 ; base free ; low-temperature ; CO-SCR ; Cu-Mn oxide spinels ; Cu/Cu3P nanoarrays ; Cu nano-substrates ; electrocatalyst ; HER ; ceria ; hydride ; CO2 hydrogenation ; single Cu doping ; density functional theory ; Cu-based catalysts ; CO + NO ; catalytic performances ; O2 resistance ; H2O and SO2 resistance ; adsorption ; dissociation ; density-functional theory calculations ; Cu-skin Cu3Au(111) surface ; CO catalytic oxidation ; CO preferential oxidation ; template ; CTAB ; mixed oxides ; copper oxides ; tin oxides ; BCN/graphene composite ; CVD ; anti-corrosion ; organocopper reagents ; Cu catalysts ; 1,4-conjugate addition ; sulfur heterocycles ; thiochromone ; thioflavanones ; 2-alkylthiochroman-4-ones ; copper ; catalysis ; amination ; amines ; polyamines ; aryl halides ; adamantane ; nanoparticles ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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  • 186
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-08-12
    Description: The extraction and exploration of cellulose-based polymers is an exciting area of research. For many years, wood (especially from bleached kraft wood pulp) was considered the main source of cellulosic compounds because of its abundance in nature. However, in the past decade, researchers have been devoted to finding alternatives to extract cellulose from byproducts of agricultural crops and/or textile wastes, which are both highly available at a very reduced raw material cost. This book brings together original research that details the recent progresses and new developments in this field, and how this research is contributing to a circular economy.
    Keywords: citrus sinensis ; nano-fibrillated cellulose ; silver nanoparticles ; acid hydrolysis ; heavy metal sorption ; anaerobic digestion ; biofuel ; biomass ; cotton-based waste ; closed-loop ; lignocellulose ; textile waste ; cellulose nanofibre ; green materials ; biopolymers ; environmental ; recycled newspaper ; composite laminates ; water resistance ; high strength ; cotton wastes ; textile ; nanomaterials ; cellulose nanocrystal ; extraction methods ; environmental application ; regenerated cellulose fiber ; Au NP ; controllably assembled ; SERS ; dimetridazole ; cellulose hydrogel ; thermo-responsive ; sustained release ; silver sulfadiazine ; burn wound ; polymer ; carpet fiber ; direct analysis in real time ; time of flight ; mass spectrometry ; function switching ; oleamide ; cellulose nanofibers isolation ; carpet wastes ; supercritical carbon dioxide ; enhanced properties ; recovery of cellulose ; textile fibers ; eco-efficiency ; circular economy ; textile industry ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 187
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Concerns have been raised with respect to the state of high-altitude and high-latitude treelines, as they are anticipated to undergo considerable modifications due to global changes, and especially due to climate warming. As high-elevation treelines are temperature-limited vegetation boundaries, they are considered to be sensitive to climate warming. As a consequence, in this future, warmer environment, an upward migration of treelines is expected because low air and root-zone temperatures constrain their regeneration and growth. Despite the ubiquity of climate warming, treeline advancement is not a worldwide phenomenon: some treelines have been advancing rapidly, others have responded sluggishly or have remained stable. This variation in responses is attributed to the potential interaction of a continuum of site-related factors that may lead to the occurrence of locally conditioned temperature patterns. Competition amongst species and below-ground resources have been suggested as additional factors explaining the variability in the movement of treelines. This Special Issue (book) is dedicated to the discussion of treeline responses to changing environmental conditions in different areas around the globe.
    Keywords: QH301-705.5 ; QK1-989 ; Q1-390 ; n/a ; tree seedling recruitment ; shrubline ; light quality ; higher altitude ; precipitation ; experimental rain exclusion ; Pinus cembra ; Changbai Mountain ; treeline dynamics ; fungal ecology ; thermal continentality ; tree regeneration ; elevational transect ; monitoring ; conifer shrub ; plant water availability ; permafrost ; foehn winds ; treeline ; Holocene ; nitrogen cycling ; carotenoids ; timberline ; 15N natural abundance ; spectrometer ; basal area increment ; palynology ; xylem embolism ; diversity ; elevational treeline ; European Alps ; temperature ; tree line ; winter stress ; photosynthetic pigments ; Pinus sibirica ; westerly winds ; relative air humidity ; ecosystem manipulation ; Larix decidua ; microsite ; polar treeline ; Central Austrian Alps ; Switzerland ; multi-stemmed growth form ; conifers ; forest edge ; history of treeline research ; soil drought ; dendroclimatology ; knowledge engineering ; Rocky Mountains ; apical control ; cloud ; postglacial ; alpine timberline ; space-for-time substitution ; climate change ; expert elicitation ; shoot elongation ; pit aspiration ; climate warming ; climate zone ; alpine treeline ; refilling ; Abies sibirica ; growth trend ; western Montana ; light quantity ; Picea abies ; Mediterranean climate ; forest climatology ; altitude ; environmental stress ; sub-Antarctic ; Erman’s birch ; photoinhibition ; tocopherol ; elevational gradients ; NDVI ; long-term trends ; sap flow ; peat ; tree seedlings ; Southern Ocean ; chlorophyll ; non-structural carbohydrates (NSCs) ; drought ; upward advance ; remote sensing data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    Pluto Press | Pluto Press
    Publication Date: 2024-03-29
    Description: Is today’s left really new? How has the European radical left evolved? Giorgos Charalambous answers these questions by looking at three moments of rapid political change - the late 1960s to late 1970s; the turn of the millennium; and post-2008. He challenges the conventional understanding of a 'new left', drawing out continuities with earlier movements and parties. Charalambous examines the 'Long '68', symbolised by the May uprisings in France, which saw the rise of new left forces and the widespread criticism by younger radical activists of traditional communist and socialist parties. He puts this side by side with the turn of the millennium when the Global Justice Movement rose to prominence and changed the face of the international left, and also the period after the financial crash of 2008 and the rise of anti-austerity politics which initiated the most recent wave of new left parties such as Podemos in Spain and Syriza in Greece. With a unique 'two-level' perspective, Charalambous approaches the left through both social movements and party politics, looking at identities, rhetoric and organisation, and bringing a fresh new approach to radical history, as well as assessing challenges for both activists and scholars.
    Keywords: Political Science ; Political Process ; Political Parties ; Political Science ; Political Process ; Political Advocacy ; Political Science ; Political Ideologies ; Communism, Post-communism & Socialism ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPL Political parties and party platforms ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPW Political activism / Political engagement ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPF Political ideologies and movements::JPFC Far-left political ideologies and movements
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  • 189
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Due to their lightweight and high specific strength, Mg-based alloys are considered as substitutes to their heavier counterparts in applications in which corrosion is non-relevant and weight saving is of importance. Furthermore, due to the biocompatibility of Mg, some alloys with controlled corrosion rates are used as degradable implant materials in the medical sector. The typical processing route of Mg parts incorporates a casting step and, subsequently, a thermo–mechanical treatment. In order to achieve the desired macroscopic properties and thus fulfill the service requirements, thorough knowledge of the relationship between the microstructure, the processing steps, and the resulting property profile is necessary. This Special Issue covers in situ and ex situ experimental and computational investigations of the behavior under thermo–mechanical load of Mg-based alloys utilizing modern characterization and simulation techniques. The papers cover investigations on the effect of rare earth additions on the mechanical properties of different Mg alloys, including the effect of long-period stacking-ordered (LPSO) structures, and the experimental and computational investigation of the effect of different processing routes
    Keywords: Arabidopsis ; abiotic stress response ; photosynthesis ; phosphoglycolate phosphatase ; photorespiration ; 2-phosphoglycolate ; Arabidopsis thaliana ; glycolate oxidase ; protein phosphorylation ; Zea mays ; Portulaca grandiflora ; C4 photosynthesis ; Crassulacean acid metabolism (CAM), evolution ; development ; PEP carboxylase ; Portulacaceae ; glycine decarboxylase ; metabolite signaling/acclimation ; TCA cycle ; Calvin–Benson cycle ; photoperiodic changes ; redox-regulation ; environmental adaptation ; Glycolate oxidase ; evolution ; Archaeplastida ; Cyanobacteria ; MCF ; oxidative phosphorylation ; mitochondrial carriers ; transporters ; energy balancing ; cyclic electron flux ; malate valve ; C3 cycle ; acclimation ; chlorophyll a fluorescence ; fluctuating light ; natural variation ; pyruvate kinase ; glycolysis ; respiratory metabolism ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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  • 190
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This Special Issue, “Plant Oxidative Stress: Biology, Physiology, and Mitigation”, published 11 original research works and 1 review article that discussed the various aspects of ROS Biology, metabolism, and the physiological mechanisms and approaches to mitigating oxidative stress. These types of research studies show further directions for the development of crop plants that are tolerant to abiotic stress in the era of climate change.
    Keywords: heat stress ; grafting ; cucumber ; bitter-melon rootstock ; polyamines ; photosynthesis ; salicylic acid ; chlorophyll fluorescence ; excess boron ; lipid peroxidation ; enzymatic antioxidant ; glutathione ; proline ; stomatal conductance ; arsenic stress ; soybean ; growth ; antioxidant enzymes ; ascorbate–glutathione cycle ; glyoxalase system ; altitudinal variation ; antioxidant activity ; bioactive compounds ; endemic species ; oxidative damage ; sequential application of antioxidants ; salinity ; Cucumis sativus ; photosynthetic efficiency ; antioxidant defense systems ; antioxidants ; cadmium ; oxidative stress ; peptone ; spinach ; alpha-tocopherol ; foliar spray ; okra varieties ; salt ; drought ; plants ; ROS ; genomics ; approaches ; integration ; abiotic stress ; antioxidant defense ; phytohormones ; pulse crop ; water deficit ; AsA-GSH pathway ; methylglyoxal ; micronutrient ; osmoregulation ; reactive oxygen species ; trace elements ; Olea europaea L. ; selenium biofortification ; olive pollen ; cytosolic Ca2+ ; Cucurbita pepo (L.) ; mineral uptake ; nucleic acids ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences
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  • 191
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This Book, entiled “Allergic Rhinosinusitis and Airway Diseases”, presents the concept of united airway disease interaction, which comprises chronic rhinosinusitis and other lower airway disorders such as asthma. This concept furthers a deeper comprehension on the pathophysiology and management of upper and lower airway diseases. In this Book, the published papers cover different interesting topics such as healthcare equality, advanced biomarkers, accurate diagnosis and treatment, occupational exposure-induced upper airway allergy and neoplastic disease mimicking chronic rhinosinusitis.
    Keywords: chronic rhinosinusitis ; B-cell lymphoproliferative disorder ; sinus ; nasal allergies ; tannery worker ; Kanpur ; asthma ; ovalbumin ; saffron ; salbutamol ; IL’s ; TNF-α ; allergic rhinitis ; bronchial asthma ; allergy ; Th17 cells ; IL-17 ; IL-33 ; microRNA ; miR ; airway mucosal inflammation ; united airway disease ; acute rhinosinusitis ; acute recurrent rhinosinusitis ; Mediterranean diet ; nutritional evaluation ; nutritional therapy ; olfactory dysfunction ; anosmia ; post-acute COVID-19 ; nitric oxide ; NO ; exhaled NO ; FENO ; nasal peak flow ; atopic status ; total IgE ; specific IgE ; childhood asthma ; immunoblot ; ImmunoCAP ; otolaryngology ; sinusitis ; ethnic groups ; patient-reported outcome measures ; quality of life ; social justice ; n/a ; bic Book Industry Communication::M Medicine
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  • 192
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This reprint turns out to be very important for the pathologies deriving from the gut microbiome and its disorders. Human health seems to be correlated with the status of our microbiome, which plays a vital role in our health. The human microbiome is associated with a wide range of diseases, from non-neoplastic to tumorigenesis, including cancer, inflammation, intestinal damage, etc. Following these statements, it is possible to deduce the paramount importance of the role of the gut microbiome and the relative consequences for human well-being.
    Keywords: microbiome ; pain ; IBS ; neuropathy ; gut microbiota ; Clostridium difficile infection ; SARS-CoV-2 ; inflammation ; intestinal microbiota ; immune protection ; mast cells ; platelets ; aging ; liver cancer ; metabolomics ; metabolites ; scientific technology ; antibiotic resistance ; virulence ; metagenomics ; human gut ; antibiotic consumption ; colon cancer ; right-sided colon cancer ; left-sided colon cancer ; tumor microbiome ; gut microbiome ; nasopharyngeal microbiome ; age differences ; sex differences ; human microbiome ; 16S rRNA sequencing ; Huntington’s disease ; neurodegeneration ; gastrointestinal microbiome ; gut-brain axis ; dysbiosis ; immune ; bacteria ; proteome ; pregnancy ; FGR ; placenta ; cancer treatment ; cardiotoxicity ; Helicobacter pylori ; methods for determining H. pylori resistance ; molecular genetic diagnostics ; phenotypic methods for determining antibiotic resistance ; geographical distribution of H. pylori antibiotic resistance ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
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  • 193
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The Special Issue, “Architectural Structure,” aims to gather general advances in human-made constructions which simultaneously are driven by aesthetic and structural engineering considerations. This Special Issue brings together twelve contributions covering the following topics: analysis of architectural typologies; the study of the mechanical performance of structural materials, structural systems and components; and the proposal of techniques to evaluate the mechanical performance in existing structures and new construction techniques.
    Keywords: recycled aggregate concrete ; block masonry ; compressive strength ; carbon emission ; stress–strain curves ; outrigger wall ; multiple openings ; deep beam ; stiffness ; shear strength ; tall building ; inverted multi tee ; prestressed concrete ; precast concrete ; structural performance ; flexural analysis ; self-compacting concrete ; non-destructive test methods ; ultrasonic pulse velocity test ; surface hardness test ; pull-out test ; maturity test ; within-test variability ; normal vibrated concrete ; concrete structures ; beams &amp ; girders ; torsion ; high-strength concrete ; prestressing ; traditional slabs ; ceramic-reinforced slabs ; shear response ; cyclic loading ; natural fiber-reinforced polymers ; NFRP ; computational design ; tailored fiber placement ; coreless filament winding ; rapid prototyping ; industry 4.0 ; lightweight structure ; Geopolymer ; Alkali activated ; tensile strength ; deformability ; experimental study ; analytical model ; reinforced concrete ; beams ; fly ash alkali activated ; bending ; thin-walled I-section ; continuous beam ; local buckling ; longitudinal stress variation ; design ultimate resistance of the cross-section ; Rudolf Steiner ; anthroposophy ; architecture ; Goetheanum ; double-steel-concrete composite shear walls ; axial and bending capacity ; failure characteristic ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 194
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: According to the National Research Council, the use of embedded systems throughout society could well overtake previous milestones in the information revolution. Mechatronics is the synergistic combination of electronic, mechanical engineering, controls, software and systems engineering in the design of processes and products. Mechatronic systems put “intelligence” into physical systems. Embedded sensors/actuators/processors are integral parts of mechatronic systems. The implementation of mechatronic systems is consistently on the rise. However, manufacturers are working hard to reduce the implementation cost of these systems while trying avoid compromising product quality. One way of addressing these conflicting objectives is through new automatic control methods, virtual sensing/estimation, and new innovative hardware topologies.
    Keywords: independent-wheel drive ; steering assistance ; nonlinear system ; active disturbance rejection control ; smooth road feeling ; city bus transport ; electric vehicles ; electrification ; software tool ; planning ; control ; charging management ; simulation ; analysis ; energy management ; hybrid electric vehicle ; powertrain electrification ; equivalent consumption minimization ; supercharging ; hardware-in-the-loop experiments ; driving force distribution ; decentralized traction system ; 4WD electric vehicle ; energy efficiency ; traction control ; efficiency optimization ; air mobility ; fuel cell hybrid aircraft ; stochastic optimal control ; drift counteraction optimal control ; normal force estimation ; unbiased minimum variance estimation ; controller output observer ; youla parameterization ; adaptive cruise control ; automated driving ; energy-saving ; fuel-saving ; optimal control ; passenger comfort ; new energy vehicles ; speed prediction ; macroscopic traffic model ; traffic big-data ; deep learning ; vehicle lateral dynamic and control ; unresolved issues ; application of speed prediction ; electric vehicle ; hybrid vehicle ; lithium ion ; ultracapacitor ; battery aging ; EHB ; EMB ; EWB ; system modeling ; bond graph ; optimization ; control design ; Youla parameterization ; robust control ; nonlinear optimization ; brake-by-wire ; actuator ; electro-mechanical brake ; electronic wedge brake ; electro-hydraulic brake ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 195
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-24
    Description: This book consists of 12 original research articles and one comprehensive review from invited chemists from around the world covering different fields of chemistry. The article on analytical chemistry features the analysis of highly polar metabolites in biological fluids, the determination of non-steroidal anti-inflammatory drugs with a gas chromatography coupled to ion trap mass spectrometry, and the synthesis of MoS2 nanostructures for the production of near-infrared photodetectors. The environmental chemistry articles include discussions on weekly and longitudinal elemental variability in hair samples, use of bottom ash as a stabilizing agent, the removal of phosphorus from the effluent of a paper company, and the chemistry and consequences of arsenic contamination of groundwater. Polymer/coating chemistry coverage includes the incorporation of superabsorbent polymers into cementitious-based composite materials, the use of licorice root extracts for edible coatings and postharvest quality improvement, and the use of mucin-grafted polyethylene glycol-based micro- for the oral delivery of insulin. The reported research on nanomaterials chemistry covers the synthesis of ZnO-doped ceria nanorods made up of CeO2/ZnO mixed oxides, and the production of carbon fiber-reinforced plastic bonded joints with novel carbon nanotube (CNT) adhesive films. A final paper on flavonol chemistry utilizes LC-MS/MS to investigate the stability of four common types of dietary flavonols.
    Keywords: carbon nanotubes ; aging ; structural health monitoring ; water uptake ; adhesive film ; surfactant ; insulin ; mucin ; polyethylene glycol ; microparticles ; toxicology ; biomass production ; Chlorella vulgaris ; microalgae ; nutrients removal ; paper industry effluent ; effluent treatment ; non-steroidal anti-inflammatory drug (NSAID) ; urine ; doping analysis ; dispersive liquid–liquid microextraction (DLLME) ; gas chromatography mass spectrometry (GC-MS) ; sewage sludge disposal ; municipal solid waste ; co-combustion ; fly ash ; bottom ash ; heavy metal stabilization ; polar amino acids ; mixed cationic-RP column ; LC-HRMS ; BMAA ; TMAO ; flavonols ; H2O2 ; saliva ; metabolism ; oxidation ; LC-MS/MS ; CeO2/ZnO mixed oxides ; zinc oxide ; ceria nanorods ; oxygen storage capacity ; CO oxidation ; licorice ; chitosan ; edible coating ; strawberry shelf life ; rheological properties ; ultrasound-assisted extraction ; mechanical properties ; microstructure ; self-healing ; SAP ; microCT ; cementitious materials ; mortar ; hairs ; variability ; week ; longitudinal ; element ; metals ; INAA ; occupational exposure ; unexposed subject ; MoS2 ; microwave-assisted hydrothermal synthesis ; low-cost photosensors ; arsenic ; groundwater ; contamination ; water quality ; domestic filter systems ; health effects ; treatment methods ; Bangladesh ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 196
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Ionizing radiation (IR) exposure can be deleterious for living tissues and eventually lead to illness or even death. DNA breakdown and the overproduction of highly reactive free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are considered initiators of IR-induced molecular and cellular damages, whereas NO, TGF-β and other pro-inflammatory cytokines are the primary effectors involved in radiation bystander effects (RIBE). Radiomodulators can reduce (radioprotectors and radiomitigators) or increase (radiosensitizers) IR damage. Past world events have highlighted the urgent need to develop predictive biomarkers of the IR absorbed dose and radiation countermeasures to reduce IR damage. Despite the strong economic and scientific efforts over the last decades, at present, drugs for effective protection against lethal IRs remain an unmet need. Moreover, the development of radiosensitizers that selectively increase IR damage in cancer cells but protecting, or at least do not affect, healthy tissues is also of unquestionable importance to improving patient survival and quality of life. It includes contributions that will help to understand the mechanisms involved in radiation-derived cellular responses and damage, the importance of free radical scavengers and antioxidant cellular defenses in preventing harm, and the relevance of the antiinflammatory response to improve recovery. In accordance, the mechanism of action and effectiveness of relevant radiomodulators are described and discussed, and novel clinical models and IR biomarker technologies are presented.
    Keywords: ferulic acid ; total body irradiation ; bone marrow microenvironment ; stem cell senescence ; bone marrow injury ; reactive oxygen species ; antioxidant defense system ; planarians ; model animal ; irradiation ; regeneration ; radioprotection ; radiation ; melatonin ; nDNA-repair ; mtDNA-mutations ; oxidation stress ; protection ; mitigation ; H2O2 ; ATP ; MDA ; GSH ; X-ray radiation ; 3T3 fibroblasts ; proliferation ; apoptosis ; cellular stress ; senescence ; peroxiredoxin 6 ; Prdx6 ; radioprotector ; pharmacologic ascorbate ; vitamin C ; pancreatic cancer ; Auranofin ; thioredoxin ; thioredoxin reductase ; peroxiredoxin ; nuclear and radiological emergencies ; radioprotectors ; radiomitigators ; radionuclide scavengers ; radiation biodosimetry ; Olea europaea L. cv. Caiazzana ; oleacein ; ionising radiation ; cancer ; radiotherapy ; normal tissue ; radiosensitization ; radiomodulation ; proteomic analysis ; oxidative modification profiling ; serum albumin ; amino acid sequences ; radiation biomarker ; human lactoferrin ; acute gamma irradiation ; C57Bl/6 mice ; survival rate ; open field test ; spleen ; serum homeostasis ; leukocytes ; stilbenoid ; electron paramagnetic resonance (EPR) ; FT-IR ; electron beam radiation ; radioresistance ; oxidative phosphorylation ; oncometabolites ; radiation response ; bioinformatics ; oxidative stress ; transcriptomics ; radiobiology database ; gene signature ; ionizing radiation ; intestine ; mucositis ; microbiome ; microbiota ; dysbiosis ; bacterial dietary supplement ; radiomitigator ; hyperthermia ; combination therapy ; synergistic effect ; oxygenation ; hypoxia ; immune response ; Tameron ; antioxidant ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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  • 197
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    ANU Press
    Publication Date: 2024-03-29
    Description: Andrew Podger's monograph, The Role of Departmental Secretaries, Personal reflections on the breadth of responsibilities today, is an important contribution to the broader public policy discourse in Australia. Andrew has been, at times, an unflinching commentator on issues of bureaucratic performance, accountability and responsiveness to government. Andrew's reflections are drawn from his own experiences within the inner circle of Australian policy-making. In this monograph, he presents a highly nuanced portrait of the role of Commonwealth departmental secretaries. Although a 'player' himself at key moments in recent policy history, Andrew is a dispassionate and thoughtful observer of events. This is not merely a memoir: this work is rich in analysis and Andrew offers a number of 'lessons learned' to be heeded (or not) by the present and future generations of policy practitioners.
    Keywords: Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPA Political science & theory ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory
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  • 198
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-08-12
    Description: This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents.
    Keywords: nanoparticles ; fungi ; drug delivery systems ; marine ; biological synthesis ; myconanotechnology ; canesten ; clotrimazole ; vulvovaginal ; vaginitis ; mycosis ; candidosis ; yeast infection ; candida ; candida albicans ; vaginal health ; anticandidal activity ; indazole ; pyrazole ; 3-phenyl-1H-indazole ; drug design ; acetylsalicylic acid (ASA, aspirin) ; capsule ; CAP64 ; Cryptococcus ; membrane potential (ΔΨM) ; photodynamic treatment ; photosensitiser ; ultrastructure ; drug repurposing ; antifungals ; repositioning ; yeasts ; emerging fungi ; multidrug resistance ; therapeutic alternatives ; new targets ; Candida auris ; Aspergillus spp. ; antifungal ; beta-glucan ; polycations ; Galleria mellonella model ; retinoids ; Candida spp. ; onychomycosis ; Malassezia spp. ; dermatophytes ; microbiology ; mycology ; all-trans retinoic acid ; Acanthamoeba ; free-living ameba ; Acanthamoeba keratitis ; isavuconazonium sulfate ; cyst ; drug ; drug discovery ; drug targets ; invasive aspergillosis treatment ; invasive fungal infections ; fission yeast ; cell wall ; β(1,3)-D-glucan synthase ; antifungal drugs ; echinocandin drugs ; echinocandin resistance ; Fks resistance hot spots ; cytokinesis ; septation ; cell separation ; cell integrity ; cell lysis ; sporotrichosis ; Felis catus ; quinones ; hydrazones ; zoonoses ; host-directed drug therapy ; azoles ; polyenes ; echinocandins ; viral infections ; azole ; synergy ; resistance ; Candida ; natural products ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-24
    Description: This reprint contains contributions focusing on recent developments in the design, synthesis, and characterization of nanocatalysts intended for applications in environmental protection and low carbon footprint power generation processes thanks to the overall effort of scientists and researchers for a cleaner and more sustainable future. New synthetic approaches to the production and in-depth characterization of innovative nanostructured composites and hybrid materials with well-controlled textural and surface chemistry properties that give performance advantages in a variety of important environmental and energy applications such as CO2 utilization/recycling, hydrogen and syngas production, biosensing, and biocatalysis as well as in ways to obtain useful materials from waste are included, among others. This reprint is the result of one of the cutting-edge Special Issues in the field of Nanoscience and Nanotechnology organized by Nanomaterials to celebrate its 10th anniversary.
    Keywords: nanocarbon ; rocket fuels ; furfuryl alcohol ; fuming nitric acid ; waste ; hypergolics ; carbon materials ; CO2 methanation ; bimetallic catalysts ; Ni-based catalysts ; promoters ; alloy nanoparticles ; bimetallic synergy ; hybrid nanoflowers ; biosynthesis ; influencing factors ; biosensing cues ; bio-catalysis ; propane ; steam reforming ; hydrogen production ; perovskite ; ruthenium ; rhodium ; La2O2CO3 ; stability ; propane steam reforming ; H2 production ; Ni ; TiO2 ; CeO2 ; YSZ ; ZrO2 ; Al2O3 ; drifts ; n/a ; HDO reaction ; transition metal phosphides ; structure ; acidity ; characterization ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint focuses on recent aspects of gravitational theory and cosmology. It contains subjects of particular interest for modified gravity theories and applications to cosmology, special attention is given to Einstein–Gauss–Bonnet, f(R)-gravity, anisotropic inflation, extra dimension theories of gravity, black holes, dark energy, Palatini gravity, anisotropic spacetime, Einstein–Finsler gravity, off-diagonal cosmological solutions, Hawking-temperature and scalar-tensor-vector theories.
    Keywords: Gauss–Bonnet ; innermost stable circular orbits ; spinning test particle ; Einstein-Maxwell-scalar black holes ; modified gravity theory ; Hawking-Page phase transition ; regular black hole ; Minkowski core ; Lambert W function ; black hole mimic ; modified and massive gravity ; two measure theories ; Einstein and Finsler gravity ; off-diagonal cosmological solutions ; nonholonomic dynamical Weyl-scale symmetry breaking ; (anisotropic) inflation ; dark energy ; reconstructing procedure ; Einstein–Gauss–Bonnet gravity ; nonlinear electrodynamics ; hawking temperature ; entropy ; heat capacity ; black hole shadow ; energy emission rate ; quasinormal modes ; cosmology ; torsion ; multifield cosmology ; anisotropic spacetimes ; Kantowski–Sachs ; anisotropic inflation ; galactic rotation ; nonspherical gravitational sources ; modified gravity ; cosmology:theory ; large-scale structure of universe ; gravitation ; fractional-dimension gravity ; dark matter ; cosmological dynamics ; Weyl integrable theory ; scalar field ; interaction ; Painlevé–Gullstrand metrics ; Lense–Thirring metric ; Killing tensor ; Killing–Yano tensor ; separability ; Carter constant ; geodesic integrability ; isometric embeddings ; symmetrical surfaces ; free embedding ; unfolded embedding ; Regge–Teitelboim gravity ; embedding theory ; black hole ; magnetic field ; chaos ; symplectic integrator ; non-linear symmetry realization ; conformal symmetry ; Ricci-based gravity ; Palatini gravity ; exoplanets ; planet’s interior ; electromagnetic ; covariant ; field ; constraints ; curved space ; alternative theories of gravity ; supermassive black hole ; stellar dynamics ; variation of constants ; inflation ; f(R)-gravity ; k-inflation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Language: English
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