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  • Biotechnology.  (262)
  • Cham :Springer International Publishing :  (262)
  • English  (262)
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  • 1
    Keywords: Medical genetics. ; Genetics. ; Biotechnology. ; Medical Genetics. ; Genetics and Genomics. ; Chemical Bioengineering.
    Description / Table of Contents: Section I: The physiology of the gene/environment interaction -- Nutrition -- Physical Exercise -- Circadian Rhythm -- Toxicants: Smoke, Alcohol and Heavy Metals -- Hormones -- Section II: Gene-Environment Interaction and Disease Susceptibility -- Obesity and Metabolic Syndromes -- Cancer -- Neurological and Psychiatric Disorders -- Asthma and allergic disorders -- Lamarck Versus Darwin: The Concept of Aquired Epigenetic Inheritance -- Section III: Genome/Epigenome -- Genetic Contribution to Epigenetic Inheritance -- The Controversial Role of DNA Methylation in Epigenetic Inheritance -- Small Non-Coding RNAs -- Chromatin Modifiers -- Soma-to-Germline Information Transfer: Questions and Promises.
    Abstract: The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between one’s genotype and the environment in which one lives. Interestingly, it seems that not only our lives, but also our ancestors’ lives, determine how we look. This newly recognized form of inheritance is known as (epi)genetic, as it involves an additional layer of information on top of the one encoded by the genes. Its discovery has constituted one of the biggest paradigm shifts in biology in recent years. Understanding epigenetic factors may help explain the pathogenesis of several complex human diseases (such as diabetes, obesity and cancer) and provide alternative paths for disease prevention, management and therapy. This book introduces the reader to the importance of the environment for our own health and the health of our descendants, sheds light on the current knowledge on epigenetic inheritance and opens a window to future developments in the field.
    Type of Medium: Online Resource
    Pages: VIII, 266 p. 11 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030352134
    DDC: 616.042
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Invertebrates. ; Biotechnology. ; Biomaterials. ; Invertebrate Zoology. ; Biotechnology. ; Biomaterials.
    Description / Table of Contents: 1. Polyphenols and flavonoids from honey: Biological applications -- 2. Chemistry and application of lac and its by-products -- 3. Silk: an amazing biomaterial for future medication -- 4. Insect Chitin and Chitosan: Structure, Properties, Production and Implementation Prospective -- 5. Recent advances in the arthropod natural product chemistry -- 6. Silkworm: A Unique Creature for Natural Products -- 7. Present and future prospects on nutritious feeding using insects -- 8. Insect Pheromones and its applications in management of pest population -- 9. Non-Protein chemical compounds from Lepidopteran insect cocoons. .
    Abstract: This book reviews the latest research on bioproducts from various economically important insects, such as silkworms, honey bees, lac and drosophila, and termites, and discusses their general, biomedical and industrial applications in detail. It includes chapters focusing on insects as a food source, probiotics, silk-based biomaterials, insect pheromones, insects as biomedicine source, pupa oil chemistry, non-protein compounds from Lepidopteran insects, insect chitin and chitosan, polyphenols and flavonoids. Model insects like Bombyx mori or bees were domesticated in Asian countries thousands of years ago. Over time, natural products from these animals became industrialized and today they attracting increasing attention thanks to their sustainability and their manifold applications in agriculture and biomedicine. The book is intended for entomologists, material scientists, natural product researchers and biotechnologists. .
    Type of Medium: Online Resource
    Pages: X, 156 p. 44 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030366100
    DDC: 592
    Language: English
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  • 3
    Keywords: Conservation biology. ; Ecology . ; Environment. ; Biotechnology. ; Pollution. ; Earth sciences. ; Geography. ; Conservation Biology. ; Environmental Sciences. ; Biotechnology. ; Pollution. ; Earth and Environmental Sciences.
    Description / Table of Contents: Preface -- Concerns and Threats of Heavy Metals Contamination on Aquatic Ecosystem -- Pollution in Aquatic Environs: Sources and consequences -- A Recent Scenario of Groundwater Quality in Northwest Himalaya, India -- Polycyclic aromatic hydrocarbons: Toxic Effects and their Bioremediation Strategies -- Mechanisms and importance of phytoremediation -- Role of Soil Biota and Associated Threats -- Viability of in-situ and ex-situ bioremediation approaches for degradation of noxious substances in stressed environs -- Bioremediation: A viable approach for degradation of petroleum hydrocarbon -- Application of macrophytes for remediation of wastewater in constructed wetlands -- Application of Biotechnology for restoration of degraded environs -- Role of Free Floating Aquatic Macrophytes in abatement of the disturbed Environs -- Genetically Modified Microbes as Biofertilizers -- Nanotechnology: A Modern Waste management approach -- Restoration of Heavy Metal Contaminated Environs through Ectomycorrhizal Symbiosis -- Index.
    Abstract: The rapid thriving of industries, conversion of agricultural land to residential areas, habitat destruction, deforestation and use of recalcitrant synthetic substances enhanced the rate of degradation of the environment. Although there are various conventional techniques for degradation and cleaning of noxious pollutants from disturbed environs, they are energy inefficient and costly to install. Bioremediation has emerged recently as an alternative and novel approach to manage and control environmental pollutants. This volume focuses explicitly on the remediation of noxious substances in stressed environs. It includes expert-contributed chapters on bio-monitoring by way of evaluating the relationship of biota with the polluted/stressed environs, sustainable plant-based degradation of noxious pollutants, and the application of biotechnologies to achieve tailored responses. Academicians, researchers, scientists and students will find this work essential for sustainable treatment of noxious pollutants. This book also serves as a core guide for training, teaching and research in conservation biology and environmental rehabilitation.
    Type of Medium: Online Resource
    Pages: XX, 340 p. 41 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030486907
    DDC: 333.9516
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Proteins . ; Biotechnology. ; Enzymology. ; Bioorganic chemistry. ; Protein Biochemistry. ; Chemical Bioengineering. ; Enzymology. ; Bioorganic Chemistry.
    Description / Table of Contents: Preface -- Chapter 1: Introduction -- Chapter 2: Enzyme Cascade Design – Retrosynthesis Approach -- Chapter 3 : Multi-Enzymatic Cascades in vitro -- Chapter 4: Multi-Enzymatic Cascades in vivo -- Chapter 5: Chemo-Enzymatic Cascades -- Chapter 6: Enzyme Cascade Kinetic Modelling -- Chapter 7: Enzyme Cascade Reaction Engineering -- Chapter 8: Enzyme Cascade Process Design and Modelling -- Chapter 9: Enzyme Cascade Reaction Monitoring And Control -- Chapter 10: Cascade reactions in non-conventional media -- Chapter 11: Perspectives.
    Abstract: This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.
    Type of Medium: Online Resource
    Pages: VII, 181 p. 103 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030657185
    DDC: 572.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biochemistry. ; Renewable energy sources. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Sustainability. ; Biochemistry. ; Renewable Energy. ; Environmental Engineering/Biotechnology. ; Sustainability.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Fractionation strategies -- Chapter 3. Biochemical conversion of cellulose -- Chapter 4. Biochemical conversion of hemicellulose -- Chapter 5. Biochemical conversion of lignin -- Chapter 6. Thermochemical conversion of cellulose and hemicellulose -- Chapter 7. Thermochemical conversion of lignin -- Chapter 8. Material application of lignin -- Chapter 9. TEA for evaluating biorefinery strategies.
    Abstract: This book focuses on the technologies developed for the conversion of all three biomass components, i.e. cellulose, hemicellulose and lignin, and their constituents, to fuels and high-value products. Both biochemical and thermochemical approaches are reviewed. Additionally, the developed technologies are described in detail and their potential applications as well as their commercial status are discussed. The early attempts to produce fuel ethanol from lignocellulosic biomass feedstock focused solely on the biological conversion of cellulose because the only organism that had been used successfully for commercial production of ethanol, i.e. Saccharomyces cerevisiae, could only ferment glucose, which was obtained from the hydrolysis of cellulose. Hemicellulose and lignin were considered as wastes in these processes and were normally removed in pretreatment processes to enhance enzymatic hydrolysis of the remaining cellulose. However, this approach was not economically feasible and as a result, the biorefinery concept was developed. In a biorefinery, in addition to ethanol, various higher-value products are produced from hemicellulose and lignin, which were previously not considered. Consequently, technologies were developed for the fractionation of biomass and conversion of hemicellulose and lignin to fuels and high-value products to improve the economic feasibility. Written and edited by a team of investigators with many years of experience in biomass processing research and development, this book is an informative resource for postgraduate students and researchers interested in biorefinery and biofuel technologies both in academia- and commercial laboratories.
    Type of Medium: Online Resource
    Pages: IX, 245 p. 43 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031058356
    DDC: 572
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Computer vision. ; Radiology. ; Biotechnology. ; Computer Vision. ; Radiology.
    Description / Table of Contents: Introduction -- Preliminaries -- Fuzzy spatial objects (fuzzy geometry and topology, set theoretic operations) -- Mathematical morphology -- Distances and similarities between fuzzy sets -- Machine learning in image processing and understanding -- Fusion -- Spatial relations -- Structural representations.
    Abstract: This book provides a thorough overview of recent methods using higher level information (object or scene level) for advanced tasks such as image understanding along with their applications to medical images. Advanced methods for fuzzy image processing and understanding are presented, including fuzzy spatial objects, geometry and topology, mathematical morphology, machine learning, verbal descriptions of image content, fusion, spatial relations, and structural representations. For each methodological aspect covered, illustrations from the medical imaging domain are provided. This is an ideal book for graduate students and researchers in the field of medical image processing. This book also: Enriches reader understanding of the latest fuzzy sets methods using higher level information (object or scene level) for advanced tasks, such as image understanding Shares many insights into fuzzy spatial objects, including fuzzy geometry and topology as well as set theoretical operations Covers in detail machine learning in image processing and understanding, with special focus on clustering, classification, and basic and advanced fuzzy methods .
    Type of Medium: Online Resource
    Pages: XIII, 302 p. 97 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031194252
    DDC: 660.6
    Language: English
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  • 7
    Keywords: Conservation biology. ; Ecology . ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Hydrology. ; Sustainability. ; Applied ecology. ; Agriculture. ; Conservation Biology. ; Environmental Engineering/Biotechnology. ; Water. ; Sustainability. ; Applied Ecology. ; Agriculture.
    Description / Table of Contents: Preface -- 1. Causes and Effects of Pesticide and Metal Pollution on Different Ecosystems -- 2. Ecotoxicology of Heavy Metals: Sources, Effects and Toxicity -- 3. Role of Modern Innovative Techniques for Assessing and Monitoring Heavy Metal and Pesticide Pollution in Different Environments -- 4. Global Scenario of Remediation Techniques to Combat Pesticide Pollution -- 5. Mycoremediation: A Sustainable Approach for Pesticide Pollution Abatement -- 6. Bio-pesticides: Application and Possible Mechanism of Action -- 7. Values of Biofertilizers for Sustainable Management in Agricultural Industries -- 8.Role of Macrophytes in Spontaneous Lacustrine Phytofiltration -- 9. Phytoremediation of Heavy Metals Using Salix (Willows) -- 10. Photo catalysis: An Effective Tool for Treatment of Dyes Contaminated Wastewater -- 11. Removal of dyes from waste water by Micellar Enhanced Ultrafiltration -- 12. Biofilm: an innovative modern technology for aquatic pollution remediation -- 13. Heavy Metal Soil Contamination and Bioremediation -- 14. Environmental Biotechnology: For Sustainable Future -- 15. Global Environmental Regulations for Management of Pesticides -- Index.
    Abstract: This book addresses the grave concerns stemming out due to conventional treatment techniques. The main focus of this book revolves round the central kernel of novel technology (bioremediation and biotechnology) which has emerged as an independent warrior to clean up and restore the disturbed environs. Furthermore, this book is a coherent assortment of diverse chapters relevant to the role of biotechnology and bioremediation for restoration of the ecosystems degraded by pesticide and heavy metal pollution. The inaugural chapters deal with the quantification of problem and its magnitude due to pesticides and heavy metals, followed by innovative modern biotechnological and bioremediation treatment technologies and sustainable techniques to remediate the persistent pollutants. It is a detailed comprehensive account for the treatment technologies from unsustainable to sustainable. Academicians, researchers and students shall find it as a complete wrap up regarding biotechnological intervention for sustainable treatment of pollution and shall suffice for the diverse needs of teaching and research.
    Type of Medium: Online Resource
    Pages: XVI, 278 p. 38 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030403331
    DDC: 333.9516
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Proteins . ; Biotechnology. ; Biology Technique. ; Protein Biochemistry. ; Chemical Bioengineering. ; Biological Techniques.
    Description / Table of Contents: Literature Search -- Sequence Analysis -- Structural Analysis -- Protein Expression Hosts and Expression Plasmids -- Gene Cloning -- Protein Expression -- Assay -- Gene Mutagenesis -- High-Throughput Screening (HTS) -- Protein Variants Analysis and Characterization -- Continuing from Protein Variants -- Employability.
    Abstract: This textbook introduces readers in an accessible and engaging way to the nuts and bolts of protein expression and engineering. Various case studies illustrate each step from the early sequence searches in online databases over plasmid design and molecular cloning techniques to protein purification and characterization. Furthermore, readers are provided with practical tips to successfully pursue a career as a protein engineer. With protein engineering being a fundamental technique in almost all molecular biology labs, the book targets advanced undergraduates and graduate students working in molecular biology, biotechnology and related scientific fields.
    Type of Medium: Online Resource
    Pages: XV, 202 p. 91 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030568986
    Series Statement: Learning Materials in Biosciences,
    DDC: 572.6
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Stem cells. ; Regenerative medicine. ; Medical genetics. ; Biotechnology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Clinical Genetics. ; Chemical Bioengineering.
    Description / Table of Contents: Application of iPSC to modelling of respiratory diseases -- Gene editing in human pluripotent stem cells: recent advances for clinical therapies -- Vascular wall as source of stem cells able to differentiate into endothelial cells -- Physiological and therapeutic roles of neuropeptide Y on biological functions -- Rho signaling-directed YAP/TAZ regulation encourages 3D spheroid colony formation and boosts plasticity of Parthenogenetic Stem Cells -- Transamniotic Stem Cell Therapy -- Regenerative medicine: Injectable cell-based therapeutics and approved products -- Stem Cell Therapy for Hepatocellular Carcinoma: Future Perspectives -- Potential of tribological properties of metalnanomaterials in biomedical applications -- The impact of the low frequency of the electromagnetic field on human.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the seventh volume of a continuing series Chapter “Application of iPSC to Modelling of Respiratory Diseases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 153 p. 30 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378455
    Series Statement: Cell Biology and Translational Medicine, 1237
    DDC: 571.6
    Language: English
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  • 10
    Keywords: Stress (Physiology). ; Plants. ; Molecular biology. ; Agriculture. ; Biotechnology. ; Plant Stress Responses. ; Molecular Biology. ; Agriculture. ; Biotechnology. ; Plant Signalling.
    Description / Table of Contents: 1. Targeted genome editing techniques in plant defense regulation -- 2. Synthetic promoters in regulating disease gene expression -- 3. Transcription factors associated with defense response against fungal biotrophs -- 4. Transcription factors associated with defense response against fungal necrotrophs -- 5. Transcription factors associated with defense response against viruses -- 6. Role of microbial bio-agents as elicitors in plant defense regulation -- 7. Transcriptional Factors Response under Biotic Stress in Wheat -- 8. Potential Transcription Factors for Biotic Stress Tolerance in Sugarcane -- 9. Role of transcription factors in response to biotic stresses in Maize -- 10. Role of transcription factors in response to biotic stresses in Pearl millet -- 11. Role of transcription factors in response to biotic stresses in Tomato -- 12. Role of transcription factors in response to biotic stresses in potato (Solanum tuberosum L.).
    Abstract: With the erratic changes in climate, crop plants are facing many forms of biotic stresses. When plants are under stress, among several gene families, regulatory genes play a vital role in signal transduction in modulating the expression of genes underpinning several defense pathways and targeting regulatory proteins (viz, transcription factors (TFs)) can be the alternative. Transcription factors directly regulate the downstream R genes and are excellent candidates for disease resistance breeding. Till date, numerous transcription factors have been identified and characterized structurally and functionally. Of them, TF families such as WRKY, NAC, Whirly, Apetala2 (AP2), ethylene responsive elements (ERF) etc. are found to be associated with transcriptional reprogramming of plant defense response. These TFs are responsive to the pathogen’s PAMPs/DAMPs - host’s PRR protein interactions and specifically binds to the cis-elements of defense genes and regulate their expression. With this background, realizing the importance of TFs in resistance breeding, this book discusses the recent research and developments in this field for various crops.
    Type of Medium: Online Resource
    Pages: VIII, 247 p. 26 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031129902
    DDC: 581.788
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Stem cells. ; Hematology. ; Regenerative medicine. ; Biotechnology. ; Stem Cell Biology. ; Hematology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Hematopoietic Stem Cells -- Mesenchymal Stem Cells -- Cord Blood Stem Cells -- Neural Stem Cells and Their Niche -- Skeletal Muscle Stem Cells -- Heart Muscle Tissue Engineering -- Induced Pluripotent Stem Cells -- Epigenetics of Somatic Cell Reprogramming -- Human Pluripotent Stem Cells and Neural Regeneration -- Dopaminergic Neuron-Related Stem Cells -- Liver Disease Modelling -- Organoids in Developmental Biology Research and Application -- Extracellular Vesicles -- Ethics in Stem Cell Applications.
    Abstract: This textbook describes the biology of different stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal cord blood, neural and muscle stem cells and also covers induced pluripotent stem cells and their applications. Further, it includes chapters on organoids, stem-cell based disease modelling, extracellular vesicles and one chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on lectures of the international master program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and participation of collaborating professors from Tongji University Shanghai, the book is a valuable source for students, postdocs and researchers, who would like to have introductory chapters on stem cell biology. It also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.
    Type of Medium: Online Resource
    Pages: XIV, 242 p. 37 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339234
    Series Statement: Learning Materials in Biosciences,
    DDC: 660.6
    Language: English
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  • 12
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Regenerative medicine. ; Biomedical engineering. ; Cytology. ; Biomaterials. ; Cells. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Cell Biology. ; Biomaterials-Cells. ; Biotechnology. ; Biomaterials.
    Abstract: Cutting-edge engineering approaches towards modelling lung homeostasis and disease have created dynamic new opportunities for interdisciplinary collaboration and unprecedented progress toward understanding and treating lung disease. This text connects established research in lung biology and physiology to innovative engineering strategies for pulmonary modelling. This unique approach aims to encourage and facilitate progress among a greater audience of basic and translational scientists, clinicians, and medical practitioners. Engineering Translational Models of Lung Homeostasis and Disease illustrates the advances in lung tissue characterization, revealing dynamic changes in the structure, mechanics, and composition of the extracellular matrix. This information paves the way for tissue-informed engineering models of pulmonary tissue, improved design of clinical materials, and advances against a variety of common pathologies. Current translational challenges are highlighted, as are engineering opportunities to overcome these barriers. This foundational text holds valuable lessons for researchers and clinicians throughout the fields of engineering, materials science, cell biology, pulmonary medicine, and clinical science. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: X, 326 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031266256
    Series Statement: Advances in Experimental Medicine and Biology, 1413
    DDC: 612.028
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomedical engineering. ; Radiology. ; Bioinformatics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Radiology. ; Computational and Systems Biology.
    Description / Table of Contents: Deep Learning in Medical Image Analysis -- Medical Image Synthesis via Deep Learning -- Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation -- Deep Learning Computer Aided Diagnosis for Breast Lesion in Digital Mammogram -- Decision support system for lung cancer using PET/CT and microscopic images -- Lesion Image Synthesis using DCGANs for Metastatic Liver Cancer Detection -- Retinopathy analysis based on deep convolution neural network -- Diagnosis of Glaucoma on retinal fundus images using deep learning: detection of nerve fiber layer defect and optic disc analysis -- Automatic segmentation of multiple organs on 3D CT images by using deep learning approaches -- Techniques and Applications in Skin OCT Analysis -- Deep Learning Technique for Musculoskeletal Analysis -- Index.
    Abstract: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
    Type of Medium: Online Resource
    Pages: VIII, 181 p. 131 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331283
    Series Statement: Advances in Experimental Medicine and Biology, 1213
    DDC: 660.6
    Language: English
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  • 14
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Entrepreneurship. ; New business enterprises. ; Public health. ; Biotechnology. ; Biomedical Research. ; Entrepreneurship. ; Public Health.
    Description / Table of Contents: Part I. What Is Wrong with Health? What Should the Future of Health Be? -- INNOVATION DESIGN for the FUTURE of HEALTH -- Health Innovations from an Innovators’ Perspective -- From SICKCARE to HEALTHCARE to HEALTH -- Future Look on Health: Opportunities -- Navigating Towards a Future of “One Health” -- Part II. Exponential Medicine + Technologies + Mindset -- Exponential Technologies for an Exponential Medicine -- Exponential Medicine: Challenges of Human Spaceflight Bringing Innovations for Earth—A Case Study -- Healthy Longevity -- The Science of Health Longevity -- Space Healthtech: Innovation Base for Longevity -- Part III. Future Health Value Propositions -- Healthcare the Melting Pot of Technology, Humanity, and Confusion -- Democratize Health Delivery -- Health Innovation Process: Definitions and Short Methodology Introductions -- Prevention, Prediction, Personalization, and Participation as Key Components in Future Health -- Digital Health Business Models: Transformation Is on the Horizon -- Value Propositions for Future Health Developments: Digital, Portable, Connected, Experience-Enhancing, Supportive, Patient-Centric, and Affordable -- (Digital) Patient Journey and Empowerment: Digital Twin -- Part IV. Innovation Methodology Basics -- Stanford Biodesign as Base: Empathy and Patient Centricity as the Main Driver -- Purpose Launchpad Methodology: Introduction -- Design Thinking for Innovations in Healthcare -- VPC to BMC to Exponential Canvas: Canvas Interconnectivity for Exponential Scaling -- Innovation Methodology I3 EME: Awareness for Biomedical Engineers -- Part V. Ethics + Health Innovation -- Integrating Ethical Considerations into Innovation Design -- Part VI. Health Innovation Design -- Case Studies Used Throughout the Book: Innovation Categories Explained -- Why Is Healthcare Different with Respect to Innovation and Entrepreneurial Activities? -- Purpose Launchpad Health (PLH) Methodology Introduction -- Part VII. Purpose Launchpad Health -- Purpose Launchpad Health: Exploration and Evaluation Phases—Actual Case Studies -- Part VIII. Health Leadership, Skills and other Methodologies -- Soft Skills Needed for Problem Understanding and Innovation Generation -- Leadership in Healthcare: A Novel Approach. Healthcare Executives’ Traits, Styles, and Approaches -- Future Skills Framework in Healthcare -- Porter’s Five Forces Analysis: Quo Vadis Immunotherapy Industry -- Part IX. Health Entrepreneurship -- Global Health Markets and Their Different Needs -- Patient: Health Relation and Digital Health Entrepreneurship -- Health Start-Up: Create Impact and be Investment Ready Intra- and Entre-Preneurs -- Regulatory Issues for Health Innovations -- Innovation Think Tank Frameworks for Resolving “The Innovator’s Dilemma” in Healthcare -- A Primer on Patents and IP for Health Innovations -- Successfully Implementing Ambidexterity in the Medical Industry -- Reverse Innovation: Circumvent Digital Health Transformation Issues -- Part X. Health Innovation Education and Incubation -- Health Innovation Design: “CAMPing” for the Unmet Clinical Need -- Health Technology Innovation Generation (HTIG) Lecture and Project Classes at AGH University -- Health Innovation Design at a University: INKA INNOLAB at Otto-von-Guericke-University -- Clinical Innovation at Acibadem Biodesign Center -- Example of a Needs-Driven Innovation Training Program: The BioMedical Design Novo Nordisk Foundation Fellowship Program -- Addressing the Healthcare Needs with Innovation Think Tank Global Infrastructure and its Methodology -- The Power of a Collaborative Ecosystem: Introducing the Edison™ Accelerator -- HealthTec Networks and Clusters (Global): Innovation Clusters in Medtech in Europe -- Leadership-Compass: “Networking and Synapting Empowered by Health Captains” -- Part XI. Purpose Launchpad Health: Toolset Templates and Principles -- PLH Templates and Principles.
    Abstract: This book highlights the reasons for an urgently needed revision of the current global healthcare setup, discusses the needed mindset for a future of health, and provides a comprehensive development toolset for disruption (and for the needed incremental innovations towards disruption). Today’s biomedical and health innovation related research in universities encourages activities that lead to incremental innovations with a relatively low risk of failure. The healthcare industry on the other hand provides tools and devices for established healthcare providers to improve the diagnosis and therapy/ treatment of the patients’ health problems. The patient is not in the center of healthcare provision however, and prevention and prediction are not core goals. The current health setup needs to be challenged and disrupted. Disruptions are coming from technologies or processes that lead to a significant (〉10x) reduction in cost or price/ performance and that also come with new business models. The need for change, effects of exponential technologies, and the needed shift to prevention and to homecare for health democratization and patient empowerment will be discussed in detail in the first parts of the book. The subsequent sections address several innovation methods with a focus on a novel meta methodology named Purpose Launchpad Health. This is followed by a comprehensive discussion on health entrepreneurship activities and needs. The final section of the book addresses how to train students to become entrepreneurial health innovators, presenting successful curricula and examples of health incubation and accelerator setups. All of the innovation tools presented and used in this book are summarized in the final chapter to help the reader get started planning an entrepreneurial venture. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments. Chapters are concise and enriched with key messages, learning objectives and real innovation examples to bridge theory and practice. This book aims to serve as a teaching base for health innovation design and to prepare for health-related entrepreneurial ventures. Readers with medical, biomedical, biotechnology, and health economics backgrounds - and anyone who wants to become a future oriented health innovator or who believes in disruptive approaches - will find this book a useful resource and teaching tool for developing validated products/ services and processes for the future of health.
    Type of Medium: Online Resource
    Pages: XXXIV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031081910
    DDC: 660.6
    Language: English
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  • 15
    Keywords: Stem cells. ; Regenerative medicine. ; Medical genetics. ; Biotechnology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Medical Genetics. ; Biotechnology.
    Description / Table of Contents: Data Analysis of Infection Rates Among Exposed Healthcare Workers Could Reveal Effective Prophylactics Against SARS-CoV-2 -- Immune Responses to SARS-CoV, MERS-CoV AND SARS-CoV-2 -- Normothermic Preservation of Liver – What does the Future Hold? -- Tissues from Post-Mortem Donors as Alternative Sources of Stem Cells for Regenerative Medicine -- New Pioneers of Optogenetics in Neuroscience -- A Current Overview of Scaffold-Based Bone Regeneration Strategies with Dental Stem Cells -- The Importance of Stem Cell Senescence in Regenerative Medicine -- Hematological Malignancies and Fertility -- Unraveling polymeric nanoparticles cell uptake pathways: two decades working to understand nanoparticles journey to improve gene therapy -- Cellular Dust as a Novel Hope for Regenerative Cancer Medicine.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the ninth volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 163 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030549176
    Series Statement: Cell Biology and Translational Medicine, 1288
    DDC: 571.6
    Language: English
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  • 16
    Keywords: Biotechnology. ; Food science. ; Biomaterials. ; Nanotechnology. ; Ceramic materials. ; Biotechnology. ; Food Science. ; Biomaterials. ; Nanotechnology. ; Ceramics.
    Description / Table of Contents: Carbon materials from various sources for composite materials -- Carbon Fibre Reinforced Polymer (CFRP) Composites: Machining Aspects and Opportunities for Manufacturing Industries -- Surface modification of graphene nanoplatelets (GNP) towards preparation of natural/synthetic rubber blend nanocomposites -- Mechanical properties of nanoclay composite materials -- Fireproof capability of rigid polyurethane foam based composite materials -- Structural behavior of composite materials in fire -- Natural resources based green composite materials -- Composite materials for wind turbine structure -- Electrochromic Smart Windows: An Energy-efficient Technology -- Graphitic Carbon Nitride/ Metal Oxides Nanocomposites and Their Applications in Engineering -- Application of Nanofiber-based Composites: Progressive Health Impact -- Polymer-based Nanocomposite: Recent Trends in Safety Assessments in biomedical applications -- Modern approach of hydroxyapatite based composites for biomedical applications -- Hybrid Composite in Orthopedic applications -- Polymer-based composite in biomedical applications -- Components of All-solid-state Ion-Selective Electrodes (AS-ISEs) -- Nanocellulose and Nanocellulose-based Composites for Food Applications -- Nanocomposite Materials in Food Packaging: Opportunities, Challenges and Safety Assessment -- Biodegradability and Composite Coatings: Past, Present and Future Prospects -- Nanocomposite Film for Food Packaging: Opening Doors to Future Applications -- Functional Chitosan-Based Composites for Potential Application in Food Industry -- Metal-insulator-metal as a biosensing platfrom .
    Abstract: Composite materials are formed when the combination of separate materials acquire new properties distinct from its components. They have a range of applications in fields such as mechanical and electrical engineering, food science and biomedicine and represent a fast-growing area of research. Composite Materials: Applications in Engineering, Biomedicine and Food Science provides an overview of current technologies and applications related to composite materials in these fields. Organized by discipline, the text encompasses a wide variety of composite materials, including polymer, ceramic, biomaterial, hydroxyapatite, nanofiber and green composites. Early chapters detail the enhanced mechanical, magnetic, dielectric properties of electrical and thermal conductive composite materials, which are essential in daily science. Subsequent chapters focus on filler or reinforcement materials, including carbon materials, hybrid materials and nanomaterials. Particular emphasis is placed on nanocomposite materials, as these have increasingly diverse field applications. Various manufacturing methods, such as the synthesis method and top-down/bottom-up manufacturing, are also discussed. Coverage of the recent progress, challenges and opportunities surrounding composite materials make this text a one-stop reference for engineers, scientists and researchers working in this exciting field.
    Type of Medium: Online Resource
    Pages: XI, 484 p. 213 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454890
    DDC: 660.6
    Language: English
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  • 17
    Keywords: Forestry. ; Nanotechnology. ; Botany. ; Biotechnology. ; Anatomy. ; Genetics. ; Forestry. ; Nanotechnology. ; Plant Science. ; Biotechnology. ; Anatomy. ; Genetics and Genomics.
    Description / Table of Contents: Preface -- Chapter. 1. Emerging nanomaterials for forestry and associated sectors: An overview -- Chapter. 2. Potential of Nanomaterials in Bio-Based Wood Adhesives: An Overview -- Chapter. 3. Nanomaterials to improve fire properties in wood and wood-based composite panels -- Chapter. 4. Wood Plastic Composites (WPC): Applications of Nanomaterials -- Chapter. 5. Nanomaterials to improve properties in wood-based composite panels -- Chapter. 6. Nanomaterials to improve the strength of wooden joints -- Chapter. 7. Application of nanomaterials for wood protection -- Chapter. 8. Nanocellulose in paper and board coating -- Chapter. 9. Green Materials for Radiation Shielding: An overview -- Chapter. 10. Formaldehyde emissions from wood-based composites: Effects of nanomaterials.
    Abstract: Bio-based materials, including those containing wood, will become increasingly important as we move to a bio-based economy. Among their many attributes, it is vitally important that these materials are renewable, sustainable with proper management and environmentally benign. Wood remains one of our most important bio-based materials. While it is an amazing material, wood still has negative attributes and drawbacks that can affect performance, including dimensional instability when wetted, vulnerability to fire and high temperatures, and susceptibility to biodeterioration. A variety of treatments have been developed to overcome these weaknesses. Among the most exciting of these treatments are nanomaterials. These materials have some exceptionally attractive properties for improving timber performance and have been the subject of intensive research over the past decade. There is a tremendous need for a single comprehensive source of information on this rapidly emerging subject with tremendous potential to enhance the performance of a variety of bio-based materials. This book contains 10 chapters, each compiled by different author(s) who are considered the top researcher(s) in their respective fields. The chapters begin with some basic background on nanomaterials and their synthesis, then explore different areas for potential applications and conclude with a review of the emerging questions about nanomaterial safety. The book is designed to provide the latest information and know-how on application and utilization of different nanomaterials to improve the properties of wood and wood-based composite panels. The contents cover some main topics in the industry including improving physical and mechanical properties, increasing resistance to biodegradation (including fungi and insects), developing wood-plastic composites (WPC), applying nanomaterials in paper and board industry, and emergence of transparent wood and radiation shielding. It also covers the use of nanomaterials to improve the performance of paints and finishes used for forest products. The book provides a single location for those interested in the field to begin.
    Type of Medium: Online Resource
    Pages: X, 362 p. 85 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031173783
    DDC: 634.9
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomaterials. ; Mathematical models. ; Dentistry. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Mathematical Modeling and Industrial Mathematics. ; Dentistry. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1 - Systematic Errors in Longitudinal Measurements -- Chapter 2 - Endodontic Treatment and Vertical Root Fracture -- Chapter 3 - Debonding of Resin Composite Restorations -- Chapter 4 - Attenuation of Curing Light through Resin Composite Restorations -- Chapter 5 - Release of Ions or Molecules from Dental Restorations -- Chapter 6 - Heat Generated from Dental Resin Composites during Curing -- Chapter 7 - Mechanical Failure of Dental Restorations – The Weakest-Link Theory -- Chapter 8 - Stability of Dental Implants -- Chapter 9 - Kinetics of Photo-polymerization -- Index.
    Abstract: This book presents a mechanistic approach—mathematical modeling—for carrying out dental materials research. This approach allows researchers to go beyond the null hypothesis and obtain a solution that is more general and therefore predictive for conditions other than those considered in a study. Hence it can be used either on its own or to complement the commonly used statistical approach. Through a series of practical problems with wide-ranging application, the reader will be guided on: How to construct a mathematical model for the behavior of dental materials by making informed assumptions of the physical, chemical, or mechanical situation How to simplify the model by making suitable simplifications How to calibrate the model by calculating the values of key parameters using experimental results How to refine the model when there are discrepancies between predictions and experiments Only elementary calculus is required to follow the examples and all the problems can be solved by using MS Excel© spreadsheets. This is an ideal book for dental materials researchers without a strong mathematical background who are interested in applying a more mechanistic approach to their research to give deeper insight into the problem at hand. Advance praise for Mathematical Models for Dental Materials Research: “This is a nice addition for research students on how to conduct their work and how to manage data analysis. It brings together a number of important aspects of dental materials investigations which has been missing in the literature. The practical examples make it much easier to understand.” – Michael F. Burrow, Clinical Professor in Prosthodontics, The University of Hong Kong “The great strengths of this volume are the real world examples of dental materials research in the successive chapters. In turn, this is an outcome of the outstanding expertise of both authors. I warmly recommend this book to the dental biomaterials community worldwide.” – David C. Watts, Professor of Biomaterials Science, University of Manchester, UK.
    Type of Medium: Online Resource
    Pages: XIV, 77 p. 41 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378493
    DDC: 660.6
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant biotechnology. ; Nanotechnology. ; Biotechnology. ; Green chemistry. ; Chemistry, Organic. ; Agriculture. ; Plant Biotechnology. ; Nanotechnology. ; Biotechnology. ; Green Chemistry. ; Organic Chemistry. ; Agriculture.
    Description / Table of Contents: Preface -- Supercritical Fluid Technologies: A Green Solvent Approach for Pharmaceutical Product Development -- Supercritical Green Solvent for Amazonian Natural Resources -- Non-catalytic and catalytic supercritical water oxidation of phenol in the wastewaters of petroleum and other industries -- Production of Platform Chemicals using Supercritical Fluid Technology -- Supercritical carbon dioxide — a glimpse from the modern era of green chemistry -- Extraction of phenolic compounds by Supercritical fluid extraction -- The Application of Supercritical Carbon Dioxide in the Extraction of Biomolecules -- Chemistry of ionic liquid, switchable solvents, supercritical carbon dioxide and sub/supercritical water -- Applications of supercritical carbon dioxide in the rubber industry -- Compressed fluids for food by-products biorefinery -- Index.
    Abstract: Globalization and industrialization involve a number of reactions, products, extractions, and separations that require the use of organic solvents. These solvents are responsible for a number of ecological concerns, including atmospheric and land toxicity. Conventional organic solvents are regarded as volatile organic compounds; some are even limited due to their potential for ozone layer depletion. While supercritical liquids exhibit physical properties that could make them ideal substitutes for these volatile compounds, there is particular interest in the use of carbon dioxide as a solvent of crude material. In particular, carbon dioxide has apparent ‘green’ properties, like its noncombustible nature, the fact that it is generally nonpoisonous, and its relative inertness. Thus, the use of supercritical carbon dioxide can provide practical improvements to the sustainability of industrial products and processes. This book provides in-depth literature in the area of industrial green processes, focusing on the separation, purification, and extraction of compounds utilizing supercritical carbon dioxide as a green solvent.
    Type of Medium: Online Resource
    Pages: XIV, 245 p. 39 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030449841
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 631.52
    Language: English
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  • 20
    Keywords: Biodiversity. ; Conservation biology. ; Ecology . ; Biology Technique. ; Biotechnology. ; Biodiversity. ; Conservation Biology. ; Experimental Organisms. ; Biotechnology.
    Description / Table of Contents: Introduction -- Chapter 1. GMOs, Biodiversity and Ecosystem Processes Part I: GM CROPS AND THEIR IMPACTS -- Chapter 2. Impact of GM crops on farmland biodiversity -- Chapter 3. GM crops: Resistance development and impact on biodiversity -- Chapter 4. Impact of Genetically Modified Crops on the Biodiversity of Arbuscular Mycorrhizal Fungi -- Chapter 5. GMOs – Impact on Non-Target Arthropods -- Chapter 6. Impacts of Genetically Engineered Crops on the Soil Microbiome, Biological Processes and Ecosystem Services -- Chapter 7. Environmental analytical and ecotoxicological aspects of Bt maize in the Pannonian Biogeographical Region of the European Union. Part II: GM INSECTS -- Chapter 8. GM Insect biodiversity and ecological interactions -- Chapter 9. Invasive Species Control and Resolution of Wildlife Damage Conflicts: a Framework for Chemical and Genetically-based Management Methods -- Chapter 10. Risk assessment of transgenic silkworms -- Part III: GM VERTEBRATES -- Chapter 11. Genetically Engineered Fish: potential impacts on aquaculture, biodiversity, and the environment -- Chapter 12. GM Farm Animals: Potential Impact on Biodiversity Including Ethical Concerns -- Chapter 13. GM Animals: Biodiversity and Bioethical Concerns and Analysis -- Part IV: RISK ASSESSMENT -- Chapter 14. Hypothesis-led ecological risk assessment of GM crops to support decision-making about product use -- Chapter 15. Risk assessment of insect-resistant genetically modified crops on non-target arthropods and benefits to associated biodiversity of agro-ecosystems -- Chapter 16. Ecological Risk Assessment for soil invertebrate biodiversity and ecosystem services -- Part V: GENE DRIVE APPROACHES -- Chapter 17. Engineered Gene Drives: Ecological, environmental, and societal concerns -- Chapter 18. Engineered Gene Drives and their Value in the Control of Vector Borne Diseases, Weeds, Pests and Invasive Species -- Chapter 19. Evaluating Gene Drive Approaches for Public Benefit -- Part VI: GOVERNANCE AND REGULATION -- Chapter 20. Governance of Emerging Technologies/Applications in the Bio/Life Sciences: Genome Editing and Synthetic Biology -- Part VII: ANNEX A -- National legal perspectives. Africa. Chapter 21. Botswana - Genetically modified organisms (GMOs) and Synthetic biology: Their potential applications and the legal perspectives -- Chapter 22. Democratic Republic of the Congo - GMOs/synthetic biology rules/regulations and biodiversity: A legal perspective -- Chapter 23. Kenya - A Review of Regulation of Genetically Modified Organisms (GMOs) - Case Study of Kenya. Chapter 24. South Africa - Synthetic Biology Regulatory Considerations and Biodiversity: A Legal Perspective for South Africa -- Chapter 25. Tunisia - The Use of Modern Biotechnology in Tunisia: Regulatory Framework -- Chapter 26. Zimbabwe - The status of Biosafety in Zimbabwe: A legal perspective. Americas -- Chapter 27. Argentina - Regulatory Framework for Genetically Modified Organisms (GMOs) -- Chapter 28. Colombia - GMOs/innovative biotechnology regulations -- Chapter 29. Ecuador - Modern biotechnology in Ecuador: development and legal framework -- Chapter 30. Honduras - GMOs/synthetic biology rules/regulations and biodiversity: A legal perspective from Honduras -- Chapter 31. Venezuela - GMOs/regulations and biodiversity: A legal perspective in Venezuela -- Asia -- Chapter 32. India - GMOs/Synthetic Biology rules/regulations and biodiversity: A legal perspective from India -- Chapter 33. Malaysia - Genetic modifications and synthetic biology regulations and biodiversity: A legal perspective for Malaysia -- Chapter 34. Pakistan - Synthetic Biology: challenges and opportunities from a biodiversity perspective in Pakistan -- Chapter 35. Thailand - GMOs and synthetic biology regulations: Thailand perspective -- Australasia -- Chapter 36. Australia - Biodiversity Considerations as Part of the Regulation of GMOs, Including Synthetic Organisms -- Chapter 37. New Zealand - GMO Rules and Regulations in New Zealand -- Europe -- Chapter 38. Czech Republic - GMO Regulations and Biodiversity: A Legal Perspective -- Chapter 39. Hungary - Hungary’s GMO-free policy and its legal background -- Chapter 40. Italy - GMOs and synthetic biology rules/regulations and biodiversity: the legal perspective of Italy -- Chapter 41. Norway - The Norwegian Gene Technology Act: Protection of Biodiversity -- Chapter 42. Slovenia - GMOs and synthetic biology regulations and biodiversity: A Slovenian legal perspective.
    Abstract: This book covers a broad spectrum of topics related to GMOs and allied new gene-based technologies, biodiversity, and ecosystem processes, bringing together the contributions of researchers and regulators from around the world. The aim is to offer a clear view of the benefits and effects of genetically modified crops, insects, and other animals on the soil microbiome and ecological processes. Contributors examine issues related to the development of risk assessment procedures and regulations designed to maximize benefits while minimizing risks. Beyond the scientific challenges of GMOs, the book explores the broad and contentious terrain of ethical considerations. The contributors discuss such questions as the unintended, possibly unforeseen, consequences of releasing GMOs into ecosystems, and the likelihood that the full effects of GMOs could take years, even decades, of close monitoring to become evident. The importance of developing a precautionary approach is stressed. The final chapter describes the critical issues of governance and regulation of new and emerging gene-based technologies, as nations grapple with the consequences of adopting the Cartagena Protocol on Biosafety (CPB). The volume includes an extensive Annex which outlines legal perspectives on the state of GMO governance around the world, with more than 20 examples from nations in Africa, South and Central America, Asia, Australasia, and Europe. .
    Type of Medium: Online Resource
    Pages: XV, 667 p. 33 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030531836
    Series Statement: Topics in Biodiversity and Conservation, 19
    DDC: 333.95
    Language: English
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  • 21
    Keywords: Plant ecology. ; Soil science. ; Conservation biology. ; Ecology . ; Agriculture. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Plant Ecology. ; Soil Science. ; Conservation Biology. ; Agriculture. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Foreword -- Preface -- Chemical fertilizers and their impact on soil health -- Microbial Bioremediation of Pesticides/Herbicides in Soil -- Pollution cleaning up techniques -- Role of Mushrooms in the Bioremediation of Soil -- Microbial degradation of organic constituents for sustainable development -- Traditional farming practices and its consequences -- Soil organic matter and its impact on soil properties and nutrient status -- Sustainable Agricultural Practices -- Values of Composting -- Introduction to Microbiota and Biofertilizers -- Fungi and their potential as Biofertilizers -- Bacillus thuringiensis as a Biofertilizer and Plant Growth Promoter -- Cyanobacteria as Sustainable Microbiome for Agricultural Industries -- Intercropping: A Substitute but Identical of Biofertilizers -- Application of Phyllosphere Microbiota as Biofertilizers -- Biofertilizers: A Viable tool for future organic agriculture -- Index.
    Abstract: The dependence of present farming on artificial input of “chemical fertilizers” has caused numerous ecological tribulations associated with global warming and soil contamination. Moreover, there is an essential requirement for realistic agricultural practices on a comprehensive level. Accordingly, biofertilizers including microbes have been recommended as feasible environmentally sound solutions for agricultural practices which not only are natural, and cost-effective but also preserve soil environs and important biota of agricultural land. In addition, it enhances the nutrient quantity of soils organically. Microbial biofertilizers promote plant growth by escalating proficient absorption of nutrients for the plants and by providing an excellent disease-fighting mechanism. Agriculture, the backbone of human sustenance, has been put under tremendous pressure by the ever-increasing human population. Although various modern agro-techniques boosted agricultural production, the excessive use of synthetic fertilizers, pesticides and herbicides have proven extremely detrimental to agriculture as well as to the environment in which it is carried out. Besides this some faulty agricultural practices like monoculture and defective irrigation, further complicate the scenario by eliminating biodiversity, increasing the efflux of nutrients into the water bodies, the formation of algal blooms, eutrophication, damaging the water quality and lowering fish stocks. Biofertilizers are the organic compounds applied to crops for their sustainable growth and the sustainability of the environment as the microbiota associated with biofertilizers interact with the soil, roots and seeds to enhance soil fertility. Application of biofertilizers results in the increased mineral and water uptake, root development, vegetative growth and nitrogen fixation besides liberating growth-promoting substances and minerals that help the maintenance of soil fertility. They further act as antagonists and play a pivotal role in neutralising soil-borne plant pathogens and thus, help in the bio-control of diseases. Application of biofertilizers instead of synthetic fertilizers could be a promising technique to raise agricultural productivity without degrading environmental quality. The present book focuses on the latest research approaches and updates from the microbiota and their applications in the agriculture industry. We believe this book addresses various challenges and shed lights on the possible future of the sustainable agricultural system.
    Type of Medium: Online Resource
    Pages: XXVII, 350 p. 174 illus., 167 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030610104
    DDC: 581.7
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Neurosciences. ; Medical care. ; Neurology . ; Biomedical engineering. ; Biotechnology. ; Neuroscience. ; Health Care. ; Neurology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1: Application of reinforcement and deep learning techniques in brain machine interfaces -- Chapter 2: Specific muscle activation patterns in athletic and orthopedic populations: considerations for using surface electromyography in assistive and biofeedback device applications -- Chapter 3: Kineto-dynamic modeling of human upper limb for robotic manipulators and assistive applications -- Chapter 4: Learning from the human hand: force control and perception using a soft-synergy prosthetic hand and non-invasive haptic feedback -- Chapter 5: Design of a soft glove-based robotic hand exoskeleton with embedded synergies -- Chapter 6: Model predictive control based knee actuator allocation during a standing-up motion with a powered exoskeleton and functional electrical stimulation -- Chapter 7: Deep brain stimulation for gait and postural disturbances in Parkinson’s disease -- Chapter 8: Cognitive and physiological intent for the adaptation of motor prostheses -- Index.
    Abstract: This book provides a comprehensive review of recent developments in the field of motor neuroprosthetics and brain-machine interfaces. Chapters in this book are provided by leading experts in the field and include topics such as the design and control of multidimensional prosthetics and exoskeletons, deep brain stimulation, functional electrical stimulation, deep learning for brain machine interfaces, biofeedback, and cognitive intent for adaptation of motor prostheses. This book is a great resource for undergraduate and graduate students, researchers, engineers from related disciplines, entrepreneurs, and anyone interested in the latest progress in the field of motor neuroprostheses.
    Type of Medium: Online Resource
    Pages: XII, 162 p. 57 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030387402
    DDC: 660.6
    Language: English
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  • 23
    Keywords: Cytology Technique. ; Plant biotechnology. ; Biology Technique. ; Plant physiology. ; Biotechnology. ; Cytological Techniques. ; Plant Biotechnology. ; Biological Techniques. ; Plant Physiology. ; Biotechnology.
    Description / Table of Contents: Introduction -- Historical Developments of Cell and Tissue Culture Techniques -- Callus Cultures -- Cell Suspension Cultures -- Protoplast Cultures -- Haploid Techniques -- Plant Propagation: Meristem Cultures, Somatic Embryogenesis Micropropagation, and Transformation of Somatic Embryos in Bioreactors -- Some Endogenous and Exogenous Factors in Cell Culture Systems -- Primary Metabolism -- Secondary Metabolism -- Phytohormones and Growth Regulators -- Cell Division, Cell Growth, Cell Differentiation -- Genetic Problems and Gene Technology -- Summary of Some Physiological Aspects in the Development of Plant Cell and Tissue Culture.
    Abstract: This textbook is clearly structured with fourteen richly illustrated chapters and practical examples for easy understanding and direct implementation. The methods and findings developed in the authors’ group are presented in detailed, revised chapters. Readers will find valuable updates on the molecular basis of biotechnological processes, secondary metabolite production and genetic engineering. In addition, the basic principles of important biotechnologies, as well as examples of specially designed crops that deliver improved productivity under stress conditions, are presented. This second edition sets the direction for future research on the basic aspects of plant tissue culture and its applications in the fields of secondary metabolite production and genetic engineering. It provides both general and specific information for students, teachers, academic researchers and industrial teams who are interested in new developments in plant tissue culture and its applications. .
    Type of Medium: Online Resource
    Pages: XXI, 459 p. 204 illus., 47 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030490980
    DDC: 571.6028
    Language: English
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  • 24
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Regenerative medicine. ; Biomedical engineering. ; Biomaterials. ; Biotechnology. ; Engineering design. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Biomaterials. ; Biotechnology. ; Engineering Design.
    Description / Table of Contents: Metallic and Ceramic Biomaterials: Current and Future Developments -- Polymers, Composites and Nano Biomaterials: Current and Future Developments -- Polyurethane Based Materials with Applications in Medical Devices -- Rapid Prototyping of Hydrogels to Guide Tissue Formation -- Engineered Scaffold Architecture Influences Soft Tissue Regeneration -- Customized Implants for Bone Replacement and Growth -- Direct Digital Manufacturing of Complex Dental Prostheses -- Digital Design and Fabrication in Dentistry -- The Development of an Artificial Finger Joint -- Computer-Aided Development of Mega Endo-Prostheses -- Smart Insoles -- Medical Applications of Additive Manufacturing -- Additive Manufacturing in Craniofacial Applications -- Additive Manufacturing in Hearing Aids.
    Abstract: This second edition maintains a focus on integrated biomaterials, computer-aided design, and physical prototyping techniques as examples of the materials and applications that are found in medical environments. All original chapters, written by renowned experts in the field, have been updated along with the addition of four new chapters on: Smart insoles Medical applications of additive manufacturing Additive manufacturing in craniofacial applications Additive manufacturing in hearing aids This wide-ranging treatise on biomaterials and prototyping applications in medicine also focuses on solid freeform fabrication, rapid prototyping, layered manufacturing, and computer-aided design in the development of prosthetic devices. This book is a must-have for bioengineers seeking a comprehensive overview of this important subject and examples of medical applications, as well as researchers and academics in the same field. .
    Type of Medium: Online Resource
    Pages: XII, 200 p. 104 illus., 60 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030358761
    DDC: 612.028
    Language: English
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  • 25
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Plant Science. ; Genetics and Genomics. ; Biotechnology.
    Description / Table of Contents: Reference genome sequence of flax -- Repeat DNA sequences in flax genomes -- Pale flax (Linum bienne): an underexplored flax wild relative -- Flax breeding -- QTL mapping: strategy, progress and prospects in flax -- Genetics of abiotic stress in flax. QTL and candidate genes for flax disease resistance -- Key stages of flax bast fiber development through the prism of transcriptomics -- Metabolomics and transcriptomics-based tools for linseed improvement.
    Abstract: The Flax Genome is a comprehensive compilation of most recent studies focused on reference genome, genetic resources and molecular diversity, breeding, QTL mapping, gene editing tools, functional genomics and metabolomics, molecular breeding via genomic selection, and genomic resources. The flax genome reference sequences and the new genome assemblies are presented. A list of flax QTL and candidate genes associated with more than 35 traits, including yield and agronomic, seed quality and fatty acid composition, fibre quality and yield, abiotic stress, and disease resistance traits, are summarized. A QTL- based genomic selection strategy and genome–editing tools are systematically introduced. In addition, huge amounts of flax genomic resources generated in the last decade are summarized. The book contains 13 chapters with about 390 pages authored by globally reputed researchers in the relevant fields to this crop The book is intended to be useful to students, teachers, and researchers interested in traditional and molecular breeding, pathology, molecular genetics and breeding, bioinformatics and computational biology, and functional genomics.
    Type of Medium: Online Resource
    Pages: XII, 294 p. 74 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031160615
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 26
    Keywords: Biotechnology. ; Bioinformatics. ; Medical genetics. ; Biotechnology. ; Computational and Systems Biology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Global Alignment of PPI Networks -- Chapter 2: Integrated Network-Based Computational Analysis for Drug Development -- Chapter 3: Effective Random Walk Models for Comparative Network Analysis -- Chapter 4: Computational Methods for Protein-Protein Interaction Network Alignment -- Chapter 5: Network Propagation for the Analysis of Multi_Omics Data -- Chapter 6: Motifs in Biological Networks -- Chapter 7: Bio Fabric Visualization of Network Alignments -- Chapter 8: Module Identification of Biological Networks via Graph Partition -- Chapter 9: Network Module Detection to Decipher the Heterogeneity of Cancer Mutations.
    Abstract: This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights. .
    Type of Medium: Online Resource
    Pages: XII, 217 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571733
    DDC: 660.6
    Language: English
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  • 27
    Keywords: Medical microbiology. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Biotechnology. ; Medical Microbiology. ; Biomedical Research. ; Pharmacology. ; Biomedical Research. ; Biotechnology.
    Description / Table of Contents: 1.Introduction to Drugs, Drug Targets and Drug Resistance -- 2.Drugs Resistance in Bacterial Diseases -- 3.Drugs Resistance Against Viral Diseases -- 4.Drug Resistance in Protozoal Infections -- 5.Antifungal Drugs: Mechanism of Action and Resistance -- 6.Drug Resistance in Ear, Nose, and Throat Infections -- 7.Drug Resistance in Skin Diseases -- 8.Drugs Resistance in Lungs Diseases -- 9.Neurological Disorders: Biochemistry of Drug Resistance and Future Challenges -- 10.Drug Resistance in Kidney Diseases -- 11.Drugs resistance in Heart Diseases -- 12.Drugs Resistance in Liver Disease -- 13.Drug Resistance in Cancer -- 14.Drugs Resistance and Treatment Failure in HIV and / or AIDS -- 15.Drug Resistance in Reproductive Diseases -- 16.Drug Resistance in Diabetes -- 17.Drug Resistance in Rheumatological Diseases -- 18.Pherotypes in Streptococcus pneumoniae and Role of CSP-1 and CSP-2 in Antibiotic Susceptibility and Resistance; Towards Development of Live Attenuated Vaccine Candidates in Inducing Netosis Based Acquired Immune Response -- 19.Hypoxia, Obesity and Drug Resistance; Towards Sustainable Development Goals and Globalization -- 20.Genetic and Molecular Mechanisms of Multidrug-resistance in Uropathogens and Novel Therapeutic Combat -- 21.Drugs Resistance Management.
    Abstract: This book provides a comprehensive discussion on the current information and evidence on the latest developments in the field of drugs resistance. Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. This leads to negative outcomes at great risk of public health; therefore, increasing efforts are dedicated to the development of a new generation of medications that will help deal with this phenomenon. Decades of technological innovations in drug design have demonstrated the potential of resistance. Enormous information on various aspects of antibiotics resistance is available. However, literature on drug resistance specifically related to infectious and non-infectious diseases is rarely presented, particularly those focusing on the mechanisms, biochemistry, kinetics, dynamics, and management of drug resistance. Therefore, there is an immense need for a systematic compilation on the available information about this issue. All the chapters are logically selected and arranged to provide state-of-the-art information about all aspects of drugs resistance. After an introductory chapter, four chapters are dedicated to infectious microbial diseases, whereas two other chapters are complimenting this theme and focusing on drugs resistance in ear, nose and throat, and skin diseases. The recent advances in the understanding of drugs resistance in lung, neurological, kidney, heart, and liver diseases are also covered. Biochemistry of drugs resistance in cancer, HIV, ocular, reproductive, and diabetes diseases is also discussed. Finally, a chapter dedicated to the “management of drug resistance” has been included. .
    Type of Medium: Online Resource
    Pages: XI, 558 p. 97 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030763206
    DDC: 616.9041
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Cancer. ; Microtechnology. ; Microelectromechanical systems. ; Biomedical engineering. ; Biotechnology. ; Cancer Biology. ; Microsystems and MEMS. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Part 1 -- Conventional nanosized drug delivery systems for cancer applications -- Homing peptides for cancer therapy -- Radiolabeling of theranostic nanosystems -- Boosting nanomedicine efficacy with hyperbaric oxygen therapy -- Part 2 -- Mesoporous Silica Nanoparticles as Carriers for Biomolecules in Cancer Therapy -- Clearable Nanoparticles for Cancer Photothermal Therapy -- Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds -- Electrospun Nanofibers for Cancer Therapy -- Nanoneedle-based materials for intracellular studies -- Part 3 -- In vitro assays for nanoparticle-cancer cell interaction studies -- 3D tumor spheroid models for in vitro therapeutic screening of nanoparticles -- In vitro and in vivo tumor models for the evaluation of anticancer nanoparticles -- Part 4 -- Nanotechnology for the Development of Nanovaccines in Cancer Immunotherapy -- Viral nanoparticles: cancer vaccines and immune modulators -- Industrial Perspective on Cancer Immunotherapy -- Index.
    Abstract: The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.
    Type of Medium: Online Resource
    Pages: VIII, 360 p. 80 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030581749
    Series Statement: Advances in Experimental Medicine and Biology, 1295
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Human physiology. ; Biotechnology. ; Regenerative medicine. ; Cytology. ; Human Physiology. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Cell Biology.
    Description / Table of Contents: Section 1: Introduction of Acellularization -- Section 2: Extra Cellular Matrix (ECM) as a Bioscaffold -- Section 3: Methods of Characterization of Acellularized Tissue -- Section 4: Methods of Sterilization of Acellularized Tissue -- Section 5: skin -- Chapter 1: Thin Skin -- Chapter 2: Thick Skin -- Section 6: Cartilage Tissue -- Chapter 1: Hyaline cartilage -- Chapter 2: Fibrocartilage -- Chapter 3: Elastic cartilage -- Section 7: Bone Tissue -- Section 8: Cardiovascular System -- Section 9: Digestive System I -- Chapter 1: Tongue -- Chapter 2: Esophagus -- Chapter 3: Stomach -- Chapter 4: Small Intestine -- Chapter 5: Large Intestine -- Section 10: Digestive System II -- Chapter 1: Liver -- Chapter 2: Pancreases -- Chapter 3: Gallbladder -- Section 11: Respiratory System -- Chapter 1: Trachea -- Chapter 2: Lung -- Section 12: Urinary System -- Chapter 1: Kidney -- Chapter 2: Bladder -- Section 13: Nerve System -- Chapter 1: Central Nerve System (CNS) -- Chapter 2: Peripheral Nerve System (PNS) -- Section 14: Female Reproductive System -- Chapter 1: Ovary -- Chapter 2: Uterus -- Chapter 3: Vagina -- Chapter 4: Cervix -- Section 15: Male Reproductive System -- Chapter 1: Prostate Gland -- Chapter 2: Testis.
    Abstract: This contributed volume is the first of a series that introduces safe, feasible, and practical decellularization and recellularization techniques for tissue and organ reconstruction. We have put special emphasis on the research areas most likely to develop well-engineered scaffolds for tissue and organ engineering, while presenting easily applicable bench-to-bedside approaches highlighting the latest technical innovations in the field. This book includes both a fundamental discussion for a broad understanding of the basis of tissue repair and substitution, as well as chapters written by world renowned specialists from 20 countries providing deeper discussions and analysis of related sub disciplines. Within these pages, the reader will find state-of-the-art protocols and current clinical challenges in cell and tissue biology, including accurate and comprehensive information on extracellular matrices, natural biomaterials, tissue dynamics, morphogenesis, stem cells, cellular fate progressions, cell and tissue properties for in-vitro and in-vivo applications. This comprehensive and carefully organized treatise provides a clear framework for graduate students and postdoctoral researchers new to the field, but also for researchers and practitioners looking to expand their knowledge on tissue and organ reconstruction.
    Type of Medium: Online Resource
    Pages: XIII, 259 p. 63 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030827359
    Series Statement: Advances in Experimental Medicine and Biology, 1345
    DDC: 612
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Genome and Transcriptome of Amaranth Species -- Chapter 2. Organelle Genomics: The Chloroplast Genome of Amaranth -- Chapter 3. Genetic and Phenotypic Odyssey: Voyage of the Grain Amaranths from the Americas to the Old World -- Chapter 4. Genetics of Betalain Pigments in Amaranth Species -- Chapter 5. Molecular Characterization of Seed Storage Proteins (SSPs) in Grain Amaranth -- Chapter 6. Genetic Diversity in Amaranth and its Close Relatives -- Chapter 7. Searching for an Identity: Functional Characterization of Taxonomically Restricted Genes in Grain Amaranth -- Chapter 8. How to Overcome Recalcitrance? Novel Strategies and Recent Advances in the Genetic Transformation of Grain Amaranth -- Chapter 9. Polyploidy and Hybridization for Amaranth Crop Improvement -- Chapter 10. Amaranth Transcription Factors in Response to Biotic and Abiotic Stresses.
    Abstract: This book describes the development of genetic resources in amaranths, with a major focus on genomics, reverse, and forward genetics tools and strategies that have been developed for crop improvement. Amaranth is an ancient crop native to the New World. Interest in amaranths is being renewed, due to their adaptability, stress tolerance, and nutritional value. There are about 65 species in the genus, including Amaranthus caudatus L., A. cruentus L., and A. hypochondriacus L., which are primarily grown as protein-rich grains or pseudocereals. The genus also includes major noxious weeds (e.g., A. palmeri). The amaranths are within the Caryophyllales order and thus many species (e.g., A. tricolor) produce red (betacyanin) or yellow (betaxanthin) betalain pigments, which are chemically distinct from the anthocyanins responsible for red pigmentation in other plants. A. hypochondriacus, which shows disomic inheritance (2n = 32; n= 466 Mb), has been sequenced and annotated with 23,059 protein-coding genes. Additional members of the genus are now also been sequenced including weedy amaranths, other grain amaranths, and their putative progenitors.
    Type of Medium: Online Resource
    Pages: XVII, 181 p. 53 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030723651
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biotechnology. ; Biomedical engineering. ; Biomedical Research. ; Biotechnology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Graviola Fruit Extraction by Ionic Liquid Microwave-assisted Extraction (IL-MAE) -- Role of Ionic Liquids in the Enzyme Stabilization: A Case Study with Trichoderma ressie Cellulase -- Role of Ionic Liquids in the Processing of Lignocellulosic Biomass -- Proliferation of rat amniotic stem cell (AFSC) on modified surface microcarrier -- Application of spectroscopic methods for the analysis of non-halal meats in food products: A narrative review -- Identification of Potential Biomarkers of Porcine Gelatin -- Gamma Ray Mutagenesis on Bacteria Isolated from Shrimp Farm Mud for Microbial Fuel Cell Enhancement and Degradation of Organic Waste -- Effect of temperature on antibacterial activity and fatty acid methyl esters of Carica papaya seed extract -- Solid-state Fermentation of Agro-industrial Waste Using Heterofermentative Lacti Acid Bacteria -- Synthesis of chitosan-folic acid nanoparticles as a drug delivery system for propolis compounds.
    Abstract: This contributed volume, “Multifaceted Protocols in Biotechnology, Volume 2”, consists of multidisciplinary methods and techniques commonly used in biotechnology studies. There are two sections covered in this book – Ionic Liquid Related Techniques & Evergreen Biotechnology Techniques. A brief introduction supports each protocol to allow easy learning and implementation. The first section consists of three chapters covering studies in modern biotechnology focusing on the role of ionic liquid techniques in extracting secondary metabolites, enzyme stabilization and biomass processing. The second section covers evergreen methodologies. It comprises five chapters covering topics on microcarrier technology for cell culture; Polymerase Chain Reaction for non-halal sources detection in food; ELISA for biomarker identification; gamma ray-induced mutagenesis for enhancing microbial fuel cells; and the effect of temperature on antibacterial activity of Carica papaya seed extract. This book will be useful to graduate students, researchers, academics, and industry practitioners working in the area of biotechnology.
    Type of Medium: Online Resource
    Pages: VII, 159 p. 45 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030755799
    DDC: 610.72
    Language: English
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    Keywords: Fungi. ; Mycology. ; Microbiology. ; Medical microbiology. ; Biodiversity. ; Plant ecology. ; Plants Evolution. ; Biotechnology. ; Fungi. ; Medical Microbiology. ; Biodiversity. ; Plant Ecology. ; Plant Evolution. ; Biotechnology.
    Description / Table of Contents: Preface -- Climate change overview -- Fungi: Essential elements in ecosystems -- Thermotolerance and adaption to climate change -- Impact of climatic change on dermatophytosis -- Climate change and the proliferation of cases of sporotrichosis -- Climate change and eumycetoma -- Effect of climate change on the geographical distribution of coccodioidomycosis -- Geographical expansion of histoplasmosis and its relation to climate change -- Impact of climate change on opportunistic mold infections -- The emergence of opportunistic yeast infections and climate change -- Climate change and allergies -- Climate change and mycotoxins -- Mycosis in natural disasters associated with climate change -- Advances and limitations in the identification of fungi -- Actions against the increase in fungal infections due to climate change: Prospects for vaccine development -- Bibliography -- Index.
    Abstract: The shift of weather patterns has affected the incidence and prevalence of infectious diseases, including mycoses. Mycoses have remained neglected due to a lack of training and recognition within the medical community. Nonetheless, these diseases remain common worldwide while frequently being underdiagnosed. Climate change affects the distribution of fungal communities, provoking outbreaks in locations where these mycoses were absent or in low frequencies. Moreover, the reports of clinical cases related to new fungal pathogens have increased due to the description of new fungal species or due to the ability of some species to shift to new hosts. Thus, this book, The Impact of Climate Change on Fungal Diseases, is a contribution to the knowledge of a global environmental phenomenon and its relation to these diseases, and it serves as a guide for health professionals to dive deep into the repercussions of climate change and how they can implement measures for the prevention and control of fungal infections.
    Type of Medium: Online Resource
    Pages: XV, 305 p. 43 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030896645
    Series Statement: Fungal Biology,
    DDC: 579.5
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Brassica juncea: A Crop for Food and Health -- Chapter 2. Botanical Descriptions of Brassica juncea: Taxonomy, Cytology, Cytogenetics and Phylogenetic Relationships -- Chapter 3. Chemical Composition of Oil and Cake of Brassica juncea: Implications on Human and Animal Health -- Chapter 4. Genepools of Brassica -- Chapter 5. Genetic Diversity Characterization and Population Structure in Brassica juncea -- Chapter 6. Classical Genetics and Traditional Breeding in Brassica juncea -- Chapter 7. Heteroploidy in Brassica juncea: Basics and Applications -- Chapter 8. Introgression Breeding in Brassica juncea -- Chapter 9. In vitro Culture for Micropropagation, Somatic Embryogenesis, Somatic Mutation, and Somatic Hybridization in Brassica juncea -- Chapter 10. Genetic Modification of Brassica juncea: Current Scenario and Future Prospects -- Chapter 11. Molecular Linkage Mapping in Brassica juncea: Founding the basis for Marker Assisted Selection -- Chapter 12. Brassica juncea Genome Sequencing: Structural and Functional Insights -- Chapter 13. Brassica juncea Genome Assemblies – Characteristics and Utilization -- Chapter 14. Resequencing in Brassica juncea for Elucidation of Origin and Diversity -- Chapter 15. Large Scale Genome Analysis: Genome Sequences, Chromosomal Reorganization, and Repetitive DNA in Brassica juncea and Relatives -- Chapter 16. Brassica juncea L. : Chloroplast Genome -- Chapter 17. Transcriptomics Research and Resources in Brassica spp -- Chapter 18. Metabolomics of Brassica juncea -- Chapter 19. Proteomics Approach to Uncoverkey Signaling Pathways in Brassica juncea in Abiotic and Biotic stress -- Chapter 20. Genomics Approaches to Understand the Evolution of Brassica juncea -- Chapter 21. Regulatory Genes in Development and Adaptation, and Their Utilization in Trait Improvementin Brassica juncea: Challenges and Opportunities -- Chapter 22. Advanced Molecular Breeding for Yield -- Chapter 23. Advanced Breeding for Oil and Oil Cake Quality in Brassica juncea -- Chapter 24. Advances in Breeding Strategies for Improving Stress Tolerance in Brassicas -- Chapter 25. Genome Editing in Polyploid Brassica Crops.
    Abstract: This book is the first comprehensive compilation of deliberations on elucidation and augmentation of the genome of Brassica juncea, one of the leading oilseed crops of the world, popularly called as brown mustard, Indian mustard, Chinese mustard, or Oriental mustard. It includes discussions on genepools; genetic diversity and its characterization; classical genetic and traditional breeding; basics and application of heteroploidy; techniques and applications of introgressive hybridization; in vitro culture for micro-propagation, somatic mutation, somatic embryogenesis, and somatic hybridization; genetic engineering including genetic transformation and gene silencing; and molecular genetic mapping and mapping of genes and comprehensive delineations on genome sequencing and comparative genomics; resequencing for elucidation of origin and diversity; large-scale genome analysis; plastid genome sequence; transcriptomics; metabolomics; proteomics; evolutionary genomics; role of regulatory genes in development and adaptation and their utilization in trait improvement; precise breeding for yield, quality, and resistance to biotic and abiotic stresses; and prospects of genome editing.
    Type of Medium: Online Resource
    Pages: XXXVII, 491 p. 36 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030915070
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biophysics. ; Senses and sensation. ; Nanoscience. ; Biotechnology. ; Biomedical Research. ; Sensory Systems. ; Nanophysics. ; Chemical Bioengineering.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Bioreceptors -- Chapter 3. Catalytic Biosensors -- Chapter 4. Affinity Biosensors -- Chapter 5. Affinity Biosensors -- Chapter 6. Label-free Biosensors -- Chapter 7. Bioreceptor Immobilization -- Chapter 8. Biochips. Chapter 9. Genome Sequencing -- Chapter 10. Genome Sequencing -- Chapter 11. Micro Electrode Arrays, Implants and Organs-on-a-Chip -- Appendix.
    Abstract: This textbook describes the basic principles and mechanism of action of biosensor systems, and introduces readers to the various types of biosensors; from affinity biosensors to catalytic, optical and label-free biosensors, the most common systems are explained in detail. Dedicated advanced sections focus on biochips and genome sequencing methods as well as organs-on-a-chip. The textbook helps readers to understand the elementary components of biosensors, and to identify and illustrate each function in the biosensor information flow, from recognition to transduction and transmission. Furthermore, readers will receive guidance in critically analyzing published studies on biosensor research, helping them to develop appropriate concepts and independently propose their own solutions. The textbook is intended for master’s students in bioengineering, biophysics, biotechnology and pharmacology that need a solid grasp of biosensor system technologies and applications, as well as students in related medical technological fields.
    Type of Medium: Online Resource
    Pages: XVIII, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030764692
    Series Statement: Learning Materials in Biosciences,
    DDC: 610.72
    Language: English
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    Keywords: Plant physiology. ; Soil science. ; Physical geography. ; Plant biotechnology. ; Biotechnology. ; Plant Physiology. ; Soil Science. ; Earth System Sciences. ; Plant Biotechnology. ; Biotechnology.
    Description / Table of Contents: 1. Recent advances in plant adaptation to climate change – An introduction to compatible solutes -- 2. Osmosensing and signaling in plants - Potential role in crop improvement under climate change -- 3. Amino acids other than proline and their participation in abiotic stress tolerance -- 4. Engineering glycine betaine biosynthesis in alleviating abiotic stress effects in plants -- 5. Improvement of abiotic stress tolerance by modulating polyamine pathway in crop plants -- 6. Engineering fructan biosynthesis against abiotic stress -- 7. The γ-Aminobutyric Acid (GABA) towards abiotic stress tolerance -- 8. Sugar alcohols and osmotic stress adaptation in plants -- 9. Crosstalk of compatible solutes with other signalling pathways in plants -- 10. Effect and importance of compatible solutes in plant growth promotion under different stress conditions -- 11. Compatible solute engineering: An approach for plant growth under climate change.
    Abstract: Plants, being sessile and autotrophic in nature, must cope with challenging environmental aberrations and therefore have evolved various responsive or defensive mechanisms including stress sensing mechanisms, antioxidant system, signaling pathways, secondary metabolites biosynthesis, and other defensive pathways among which accumulation of osmolytes or osmo-protectants is an important phenomenon. Osmolytes with organic chemical nature termed as compatible solutes are highly soluble compounds with no net charge at physiological pH and nontoxic at higher concentrations to plant cells. Compatible solutes in plants involve compounds like proline, glycine betaine, polyamines, trehalose, raffinose family oligosaccharides, fructans, gamma aminobutyric acid (GABA), and sugar alcohols playing structural, physiological, biochemical, and signaling roles during normal plant growth and development. The current and sustaining problems of climate change and increasing world population has challenged global food security. To feed more than 9 billion, the estimated population by 2050, the yield of major crops needs to be increased 1.1–1.3% per year, which is mainly restricted by the yield ceiling. A major factor limiting the crop yield is the changing global environmental conditions which includes drought, salinity and extreme temperatures and are responsible for a reduction of crop yield in almost all the crop plants. This condition may worsen with a decrease in agricultural land or the loss of potential crop yields by 70%. Therefore, it is a challenging task for agricultural scientists to develop tolerant/resistant varieties against abiotic stresses. The development of stress tolerant plant varieties through conventional breeding is very slow due to complex multigene traits. Engineering compatible solutes biosynthesis by deciphering the mechanism behind the abiotic tolerance or accumulation in plants cell is a potential emerging strategy to mitigate adverse effects of abiotic stresses and increase global crop production. However, detailed information on compatible solutes, including their sensing/signaling, biosynthesis, regulatory components, underlying biochemical mechanisms, crosstalk with other signaling pathways, and transgenic development have not been compiled into a single resource. Our book intends to fill this unmet need, with insight from recent advances in compatible solutes research on agriculturally important crop plants.
    Type of Medium: Online Resource
    Pages: XII, 266 p. 28 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030806743
    DDC: 571.2
    Language: English
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    Keywords: Biotechnology. ; Feminism. ; Feminist theory. ; Economic development. ; Biotechnology. ; Feminism and Feminist Theory. ; Development Studies.
    Description / Table of Contents: 1. Introduction -- 2. Environment as a feminist issue -- 3. Silesian coal: history of Silesian industrialisation, the emergence of industrial society and its present restructuring -- 4. Silesian modernizations: analysis of the discourses of change -- 5. Coal perception in the region -- 6. Silesian narratives about the energy and ecology -- 7. The changing roles and values of Silesian women -- 8. Silesian women’s identity: the might of myth -- 9. Women's activity: "I" towards the change -- 10. Post-coal Silesia – the emergence of new regional identity -- 11. Upper Silesia: towards a sustainable future?.
    Abstract: This volume takes an ecofeminist perspective in analysing societal changes related to energy transition, with a focus on Upper Silesia in Europe, following the closure of coal-mining industries in the region. It provides both a macro and micro view of how energy transition in societies built around an energy industry can lead to major shifts in societal and familial dynamics, and how women locate themselves in this transition period affecting the economy as well as social and environmental structures and values. Densely populated Upper Silesia in southern Poland, with one of the longest histories of industrialization, extractivism and environmental degradation in Europe, can be considered as a microcosm of regions that have undergone such changes due to energy transition. The traces of telling socio-economic changes, as well as the tangle of modernity and conservatism, are both clearly visible in the local region and society. The book documents the Silesian changes and highlights the female perspective: their culture, identities, as well as empowerment and the agency. The paradigm of feminist and masculinity studies helps in presenting the complexity and the challenges of the just energy transition. This is a topical volume, given that many regions of the world are undergoing similar changes, and is an interesting read for decision-makers, policy experts, environmentalists, as well social scientists who study issues related to sustainability and environmental/societal challenges in energy transition. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030784164
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Religion and sociology. ; Biotechnology. ; Sociology of Religion. ; Biotechnology.
    Description / Table of Contents: Introduction -- Chapter 1. Religion outside one’s homeland -- Chapter 2. Asylum seekers, immigrants, new Europeans: setting the scene -- Chapter 3. Young foreign Christian Catholics: a portrait -- Chapter 4. Being Muslim in Hard Times in Europe: New Opportunities and Old Challenges -- Chapter 5. God will save us! Faith, identity and practices in refugee welcoming centers -- Chapter 6. Similarities and differences: the Me3 generation at the mirror -- Chapter 7. Does religious capital still matter? Local secularized societies face with a renewal of religious pluralism -- Concluding remarks.
    Abstract: This monograph considers the Catholic/Christian religious identity of young immigrants within the migratory diasporas in Southern Europe. It details important ethnographical work on various groups, such as the family, ethnic communities, and peers. The author also considers the role of institutional figures in mainstream society. These include teachers, administrators, and social workers. This valuable research material helps readers to better understand the viewpoint of young people (especially the children of immigration) in relation to various environments which are important in their lives. The investigation examines theoretical and practical questions regarding the study of relations between religion and migrations. It pays particular attention to both the youth perspective and the effects of the current refugee crisis on the perception of religious diversity and identity. Coverage also looks at similarities and differences between young migrant and their native peers. In addition, three case studies further help illustrate the main points of the author's argument. The book uses preliminary research carried out in Italy. It also features interviews collected in Portugal and Spain. Those interviewed include people with migratory background who are permanent residents, belong to the second generations, or are recently-arrived asylum seekers. Overall, the author provides readers with an interesting and innovative portrait of children of immigrants and their relations with faith in the post-secularized Europe: indeed, by considering both academic debates and original empirical data, the book offers the possibility of reframing the link between migrations and religious identities. .
    Type of Medium: Online Resource
    Pages: XXVII, 130 p. 5 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030840563
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Pharmacology. ; Biochemical markers. ; Analytical chemistry. ; Biotechnology. ; Immunology. ; Pharmacology. ; Biomarkers. ; Bioanalytical Chemistry. ; Biotechnology.
    Description / Table of Contents: Microheterogeneity of antibody molecules -- Part I: Analytical Methods -- Lectin and LC based methods for immunoglobulin (G) glycosylation analysis -- Mass spectrometry-based methods for immunoglobulin G N-glycosylation analysis -- CE based methods for Ig(G) glycosylation analysis -- Automation of Ig glycosylation analysis -- Bioinformatics in immunoglobulin glycosylation analysis -- Part II: Biosynthesis & Regulation -- N-glycan biosynthesis: Basic principles and factors affecting its outcome -- Genetic regulation of immunoglobulin G glycosylation -- Epigenetics of immunoglobulin G glycosylation -- IgG changes in aging and other inflammatory conditions -- Estrogen-driven changes in immunoglobulin G Fc glycosylation -- Part III: Effector Functions & Diseases -- Sweet rules – linking glycosylation to antibody function -- Immunoglobulin G glycosylation in diseases -- Immunoglobulin A glycosylation and its role in diseases -- Part IV: Applications -- Importance and monitoring of therapeutic immunoglobulin G glycosylation -- Glycosylation of plant-produced immunoglobulins -- The rapidly expanding nexus of immunoglobulin G N-glycomics, suboptimal health status, and precision medicine -- Glycosylation of antigen-specific antibodies - Perspectives on immunoglobulin G glycosylation in vaccination and immunotherapy.
    Abstract: This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 591 p. 66 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030769123
    Series Statement: Experientia Supplementum, 112
    DDC: 571.96
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Chemistry, Organic. ; Food science. ; Biotechnology. ; Pharmacology. ; Organic Chemistry. ; Food Science. ; Biotechnology.
    Description / Table of Contents: Chapter 1 The World of Carbohydrates -- Chapter 2 Basic Knowledge of Glycobiology -- Chapter 3 Carbohydrates involved in Diseases -- Chapter 4 Detection of Carbohydrate by Colorimetric Methods -- Chapter 5. Analytical Techniques to Study Carbohydrates -- Chapter 6 Monosaccharide Composition Analysis -- Chapter 7 Carbohydrate Analysis of Glycoconjugates -- Chapter 8 Structural Characterization of Released Glycans -- Chapter 9 Analysis of Sialic Acids -- Chapter 10 Carbohydrate Microarray Technology -- Chapter 11 Analysis of Carbohydrates by Mass Spectrometry -- Chapter 12 Analysis of Carbohydrates by Nuclear Magnetic -- Chapter 13 Glycobioinformatics -- Chapter 14 Concluding Remarks. .
    Abstract: The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.
    Type of Medium: Online Resource
    Pages: XXV, 350 p. 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030777913
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agricultural biotechnology. ; Biotechnology. ; Soil science. ; Botany. ; Environment. ; Agricultural Biotechnology. ; Biotechnology. ; Soil Science. ; Plant Science. ; Environmental Sciences.
    Description / Table of Contents: 1. Introduction -- 2. Biotechnology of 21st Century -- 3. Considerations on the Scaling of biological and chemical reactors -- 4. Design of a cultivation media for the production of metabolites with practical application in the biodegradation of industrial dyes -- 5. Obtaining and characterizing new biomaterials based on starch, for use in the food and health industry -- 6. Influence of immersion time in pitahaya (Hylocereus undatus) proteolytic enzyme solutions on the texture of bovine meat -- 7. Determination of free amino acids in fermented and toasted cocoa (Theobroma cacao) samples, using high performance liquid chromatography with UV detection by diode arrangement -- 8. Characterization of cassava and bee wax residues for their use in the obtaining of bioplastic -- 9. Development of a thermoplastic material from the residues of the banana (Musa paradisiaca) -- 10. Chemical ecology and its role in the conservation of threatened species: a case study in the Galapagos islands -- 11. Energy evaluation of solid biofuels made from mixtures of lignocellulosic biomass -- 12. Reforestation and conservation of vegetable germ plasm: challenges and expectations -- 13. Characterization of Moniliophthora roreri evans and evaluation of biological control alternatives in cacao (Theobroma cacao), for the Ecuadorian amazon -- 14. Application of biotechnology to the search and selection of PGPR in the control of phytosanitary problems in cocoa (Theobroma cacao) and banana (Musa acuminata) -- 15. Sustainability of organic quinoa cultivation (Chenopodium quinoa) in communities of colta Ecuador -- 16. Effects of artificial light intensity and temperature on the growth of lettuce (Lactuca sativa l.) in a vertical urban farm in low cost indoor -- 17. Efficiency of led lights in the propagation and field of summer flowers in Ecuador -- 18. Evaluation of extraction methods to obtain a natural flocculant from the tamarind seed (Tamarindus indica) -- 19. Bicomponent adsorption of Brilliant blue FCF and tartrazine under dynamic conditions using rice husk -- 20. Kinetic approach to the biocoagulation process of mixtures of Moringa oleífera and Caesalpinia spinosa in synthetic turby water -- 21. Sustainable alternatives in the treatment of liquid industrial waste -- 22. Biodegradation of industrial dyes with enzymatic extracts obtained in FES and FEL systems with Pleurotus djamor -- 23. Removal of petroleum hydrocarbons from medium and soil (lab & field conditions) by microorganisms isolated from the Ecuadorian amazon rainforest -- 24. Chemistry of natural products -- 25. Evaluation of the antimicrobial activity of natural extracts of altamisa (Ambrosia artemisiifolia) and melissa (Melissa officinallis) for the control of pathogenic agents -- 26. Phenolic compounds of cocoa (Theobroma cacao) shell extraction and antimicrobial activity -- 27. Susceptibility to antimicrobials in strains of environmental origin, a public health problem -- 28. Inhibition effect of oregano (Origanum vulgare) essential oil on an active biodegradable film -- 29. Current Challenges and Future Prospective of Biotechnology.
    Abstract: This contributed volume compiles the latest improvements in the field of biotechnology. It focuses on topics that comprises industrial, environment, agricultural and medical related issues to technology and biological studies and exhibits the correlation between the biological world and the dependence of humans on it. The book is organized into five parts covering the role of biotechnology in industrial products, environmental remediation, agriculture and pharmacological agents. Ranging from micro-scale studies to macro, it covers a huge domain of agricultural biotechnology and focuses on important commercial crops (e.g. cacao and coffee), arbuscular mycorrhizal fungi, flow and distribution of phosphorus in agricultural soils in the Latin American region. Overall, the book portrays the importance of modern biotechnology and its role in solving the problems in modern day life. The book is a ready reference for practicing students, researchers of environmental engineering, chemical engineering, agricultural engineering, and other allied fields likewise.
    Type of Medium: Online Resource
    Pages: XXII, 448 p. 67 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030801083
    DDC: 630
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Microbial ecology. ; Industrial microbiology. ; Microbiology. ; Environmental Engineering/Biotechnology. ; Microbial Ecology. ; Industrial Microbiology.
    Description / Table of Contents: 1. Sulfate-reducing prokaryotes: Changing paradigms -- 2. Characteristics and taxonomy -- 3. Reduction of sulfur and nitrogen compounds -- 4. Electron transport proteins and cytochromes -- 5. Systems contributing to the energetics of SRP -- 6. Cell biology and metabolism -- 7. Geomicrobiology, biotechnology, and industrial applications -- 8. Biocorrosion -- 9. Ecology of dissimilatory sulfate reducers: Life in extreme conditions and activities of SRB -- 10. Interactions of SRB with animals and plants.
    Abstract: The abundance of sulfate-reducing bacteria and archaea (SRBA) is impressive and new isolates are being reported continuously. A few decades ago, only two genera of dissimilatory sulfate reducers had been identified and as of 2018, 92 genera containing more than 420 species of SRB and several species of archaea have been isolated. This book addresses the historical background of SRBA research and reviews the current status of research examining the growth of these anaerobic microorganisms. Additionally, this book covers metabolic and genomic diversity, enzymatic processes, response to stress, biocorrosion of ferrous metals, biogeochemical processes and interactions with other microorganisms in the anaerobic biosphere. It highlights the unique cellular and molecular features of these microorganisms, discusses the production and consumption of gases and reviews genomic content influencing their metabolic capabilities. Examples are provided of detoxification reactions to alleviate pollution situations, growth in in hostile environments including low nutrient availability, and the effects of sulfate-reducing bacteria (SRB) on human and animal hosts.
    Type of Medium: Online Resource
    Pages: XI, 564 p. 62 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030967031
    DDC: 579
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Medical genetics. ; Biotechnology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Brief Introduction to CRISPR Cas 9 -- Chapter 2: Introduction To Anticipatory Ethics -- Chapter 3: CRISPR, Phenomenology and Lived Experience -- Chapter 4: CRISPR and the Concept of Personhood -- Chapter 5: The use and access to CRISPR in historically socio-economically disadvantaged and marginalized communities -- Chapter 6: Future use of CRISPR: Gene Drive -- Chapter 7: Future use of CRISPR II: CRISPR Kill Switches -- Chapter 8: Domestic and International Regulation of CRISPR -- Chapter 9: Policy Recommendations with respect to CRISPR Germline Editing in Humans -- Chapter 10: Conclusions.
    Abstract: Can we move forward with the use of CRISPR in humans without a well-formed policy and ethical framework to support it? In this new book, neuroscientist Michael W. Nestor and philosopher Richard Wilson argue that the answer is a resounding “no.” Does an ethical and policy program need to be restrictive concerning the use of CRISPR in humans? Nestor and Wilson argue that, although the future of gene editing in humans is inevitable using CRISPR technologies, the scientific, policy, ethics, and clinical communities must work together to provide the necessary frameworks to help CRISPR flourish as an essential tool to treat human disease. To achieve the most inclusive, equitable, and ethically sound use of CRISPR in humans, the scientific/policy/clinical community must involve the most comprehensive set of stakeholders possible, including the lay public. This book sets a framework for shared understanding and discussion across disciplines with an appeal to scientists and non-scientists alike. The authors urge all stakeholders to engage in active dialogue about the appropriate context for using CRISPR and other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, exploring its positive potential to treat mental disorders and the potential to induce other cognitive enhancements.
    Type of Medium: Online Resource
    Pages: XIX, 145 p. 13 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030983680
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Biomaterials. ; Biology Technique. ; Biotechnology. ; Biomaterials. ; Biological Techniques.
    Description / Table of Contents: Introduction to Biobanking -- Scientific Relevance, Problems and the Destitution for Principles of Biobanks and Biobanking Activities -- Types of Biobanks -- Ethical and Legal Principles in the Field of Biobanking -- Business Planning for Biobanks -- Biobanking Concepts Specific for Developing Countries -- Methods of Implementation and Set-up of National Biobanking Networks -- Implementation of Ethical and Legal Considerations in a Biobanking Network -- Collection and Management of Samples -- Quality Control and Risk Management in Biobanks -- Governance and Stakeholder Analysis -- Biobanking IT Systems, Database Structure and Web Applications -- Management Model and Sustainability Plan of Biobanks -- Sustainability Plan and Project Management of a Biobanking Network -- Establishing a Biobank Using Standardisation -- Science and Innovation of Biobanks -- Running a Biobank Network -- Infrastructure: Delivering on the Promise of Biobanking -- Design Considerations and Equipment of Biobanks -- Software Tools for Biobanking in LMICs -- The Importance of Cancer Biobanks in Low- and Middle-Income Countries -- Biobanking in Paediatrics: A Look from Armenia as a Middle-Income Country -- Biobanking of the Central Nervous System -- The Importance of Biobanking COVID-19 Samples -- Oncobiobanking in a Middle-Income Country: The Example of Russia -- Sustainability of Biobanks and Biobanking in LMICs -- Biobanks for Enabling Research and Development by Trusted Patient Data Environment -- Future Perspective of the Biobanking Field.
    Abstract: This book introduces the fundamentals of biobanking and guides through the practical planning thereof, with a special focus on the situation in low- and middle-income countries. On the example of the setup of a Ukrainian biobank the book discusses the main steps and aspects of successful biorepository implementation and management. Topics covered include collection, storage and shipping of samples, establishment of an IT system, development of a sustainability plan, and project and risk management. Furthermore, the importance of the formation of international biobanking societies such as the Ukraine Association of Biobanks is highlighted, and their main objectives and tasks are discussed. The book addresses life science and business professionals as well as national authorities who are interested in biobanking in general and in setting up a biobank in particular.
    Type of Medium: Online Resource
    Pages: XVII, 235 p. 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030876371
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Life sciences. ; Physiology. ; Agriculture. ; Biotechnology. ; Life Sciences. ; Animal Physiology. ; Agriculture.
    Description / Table of Contents: Chapter 1: Nutrition and Metabolism: Foundations for Animal Growth, Development, Reproduction, and Health -- Chapter 2: Insights into the Regulation of Implantation and Placentation in Humans, Rodents, Sheep, and Pigs -- Chapter 3: A Role for Fructose Metabolism in Development of Sheep and Pig Conceptuses -- Chapter 4: Nutritional Regulation of Embryonic Survival, Growth and Development -- Chapter 5: Phosphate, Calcium, and Vitamin D: Key Regulators of Fetal and Placental Development in Mammals -- Chapter 6: Nutritional and Physiological Regulation of Water Transport in the Conceptus -- Chapter 7: Amino Acids in Microbial Metabolism and Function -- Chapter 8: Potential Replacements for Antibiotic Growth Promoters in Poultry: Interactions at the Gut Level and their Impact on Host Immunity -- Chapter 9: Microbiomes in the Intestine of Developing Pigs: Implications for Nutrition and Health -- Chapter 10: L-Arginine Nutrition and Metabolism in Ruminants -- Chapter 11: Hepatic Glucose Metabolism and Its Disorders in Fish -- Chapter 12: Protein-Sourced Feedstuffs for Aquatic Animals -- Chapter 13: Functional Molecules of Intestinal Mucosal Products in Animal Nutrition and Health -- Chapter 14: Use of Genome Editing Techniques to Produce Transgenic Farm Animals -- Chapter 15: Cows as Bioreactors for the Production of Nutritionally and Biomedically Significant Proteins -- Chapter 16: Use of Agriculturally Important Animals as Models in Biomedical Research -- Chapter 17: Pigs (Sus Scrofa) in Biomedical Research.
    Abstract: This book covers hot topics in the nutrition and metabolism of terrestrial and aquatic animals, including the interorgan transport and utilization of water, minerals, amino acids, glucose, and fructose; the development of alternatives to in-feed antibiotics for animals (e.g., swine and poultry); and metabolic disorders (or diseases) resulting from nutrient deficiencies. It enables readers to understand the crucial roles of nutrients in the nutrition, growth, development, and health of animals. Such knowledge has important implications for humans. Readers will also learn from well-written chapters about the use of new genome-editing biotechnologies to generate animals (e.g., cows and swine) as bioreactors that can produce large amounts of pharmaceutical proteins and other molecules to improve the health and well-being of humans and other animals, as well as the growth and productivity of farm animals. Furthermore, the book provides useful information on the use of animals (e.g., cattle, swine, sheep, chickens, and fish) as models in biomedical research to prevent and treat human diseases, develop infant formulas, and improve the cardiovascular and metabolic health of offspring with prenatal growth restriction. Editor of this book is an internationally recognized expert in nutrition and metabolisms. He has about 40 years of experience with research and teaching at world-class universities in the subject matters. He has published more than 660 papers in peer-reviewed journals, 90 chapters in books, and authored two text/reference books, with a very high H-index of 127 and more than 66,000 citations in Google Scholar. This publication is a useful reference for nutrition and biomedical professionals, as well as undergraduate and graduate students in animal science, aquaculture, zoology, wildlife, veterinary medicine, biology, biochemistry, food science, nutrition, pharmacology, physiology, toxicology, and other related disciplines. In addition, all chapters provide general and specific references to nutrition and metabolism for researchers and practitioners in animal agriculture (including aquaculture), dietitians, animal and human medicines, and for government policy makers.
    Type of Medium: Online Resource
    Pages: VI, 346 p. 43 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030856861
    Series Statement: Advances in Experimental Medicine and Biology, 1354
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Economic Value and Research Significance of Moso Bamboo -- Chapter 2. Moso Bamboo Germplasm Resources in China/World -- Chapter 3. Biological Traits of Moso Bamboo -- Chapter 4. Moso Bamboo Genome -- Chapter 5. Moso Bamboo Transposon -- Chapter 6. Transcriptome of Moso Bamboo -- Chapter 7. Moso Bamboo Alternative Splicing (AS ) and Polyadenylation -- Chapter 8. Characterizations and Function of Transcript Factor Gene families -- Chapter 9. MicroRNAs of Moso Bamboo -- Chapter 10. Mitochondrial Genome of Endophytic Fungi from the Seed of Moso Bamboo -- Chapter 11. Breeding Strategies of Moso Bamboo.
    Abstract: This book is the first comprehensive compilation describing the botanical traits, genetic resources, whole genome sequencing, Mitochondrial genome, transcriptomes of different organs with developmental stages, transcription factors, delineating gene evolution of gene family in Bambusoideae, alternative splicing (AS) and polyadenylation, case studies for economically important traits such as internode length, shoot fast growing, flowering, ageing and stress-resistant genes and small RNAs-mediated gene regulation of moso bamboo flowering and other developmental stages. Applications of transcriptome and genome approaches in moso bamboo in general and the prospects of transgenic breeding and genome editing technologies in bamboo are also discussed. Altogether, the book comprises eleven chapters covered over 200 pages authored by the researchers involved in genomic science, molecular biology, and breeding. This book appeals to graduate students, post-graduate students, research scholars, researchers, and industry players in the field of plantation bamboo in general, bamboo processing and bamboo garden owner and fans of bamboo culture in particular.
    Type of Medium: Online Resource
    Pages: XXII, 208 p. 124 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030808365
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 46
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Aging. ; Medicine Research. ; Biology Research. ; Public health. ; Biotechnology. ; Psychiatry. ; Ageing. ; Biomedical Research. ; Public Health. ; Chemical Bioengineering. ; Psychiatry.
    Description / Table of Contents: Senescence opposed to longevity -- Genetics, the language of Proteomics -- Plants Uncover Senescence Animals Way Off Humans -- Rejuvenation stops Senescence -- Overlap of Senescence with Disease -- Mosaic Restricted to the Individuum -- Remaining Time until Death -- Laboratory Checkups -- eroprotectors.
    Abstract: This book is about lifelong ageing of humans. The basic biochemical and genetic mechanisms remain ill known, and differ among individuals. The book starts out to explore the plant and animal kingdoms to answer questions human ageing needs for understanding. First, we come to scrutinize time running out and what ‘normal’ means with impacts on the genome and on protein half- lives and function. Ageing goes beyond biochemical skid treated by geroprotector drugs, including biosimilars; albeit early diagnosis with standard medical laboratory assays, here addressed, sheds light with focus on basic research. Modern tools, including machine learning, and DNA technology, e.g. genomics, have already provided for unanticipated insights. The chapters then turn around senescence of the entire organism based on variable ageing of single organs embedded in neuronal networks . Psychological stress factors, dementia opposed to vigilance, and distinction of ageing from overt disease are contrasting in humans and are opposed in the book. Senescence, seen as a one way track may be reverted into rejuvenation, made possible by insights into immunosenescence and genomic approaches. Risk management in health insurance finds important clues in this book. The topics addressed between the book covers help to understand the trend to the ever- prolonging life expectancy beyond the centenarian age group; nursing care takers and pharmaceutical industry are invited to understand what’ is going on in senior people to make their geriatric population remain fit or become frail.
    Type of Medium: Online Resource
    Pages: XXIII, 132 p. 38 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031322761
    DDC: 571.878
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Genomic Designing For Abiotic Stress Tolerant Soybean -- Designing the Rapeseed Genome for Abiotic Stress Tolerance -- Sunflower and Abiotic Stress: Genetics and Breeding for Resistance in the Post-Omics Era -- Integration of Genomics Approaches in Abiotic Stress Tolerance in Groundnut (Arachis hypogaea L.): An overview -- Drought Tolerance in Rape and Mustard: Conventional and Molecular Approaches -- Genomic Designing For Sesame Resistance To Abiotic Stresses -- Abiotic Stresses in Castor Plant -- Designing Genomic Solutions to Enhance Abiotic Stress Resistance in Flax.
    Abstract: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in oilseed crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The eight chapters each dedicated to a oilseed crop in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Type of Medium: Online Resource
    Pages: XXIII, 283 p. 18 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030900441
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biomechanics. ; Biotechnology. ; Biomedical engineering. ; Regenerative medicine. ; Biomechanics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: 1 Modeling in Biomechanics 1 -- 1.1 The different perspectives 2 -- 1.1.1 The engineering approach 2 -- 1.1.2 The clinical approach 2 -- 1.1.3 The pre- clinical approaches 2 -- 1.2 Opportunities and challenges 2 -- 1.3 Statistical analysis 3 -- 1.3.1 Probability distributions 4 -- 1.3.2 Hypothesis testing 7 -- 1.3.3 Correlation amongst variables 9 -- 1.3.4 Regression modeling 10 -- 1.3.5 Mean difference test 13 -- 1.3.6 Study design 14 -- 1.4 Model definition 16 -- 1.5 Model development and testing 17 -- 1.5.1 Sensitivity analysis 17 -- 1.5.3 Validation 21 -- 1.6 Case study: Biomechanical Rupture Risk Assessment (BRRA) 21 -- 1.6.1 Short comings of the current AAA risk assessment 21 -- 1.6.2 Intended Model Application (IMA) 21 -- 1.6.3 Failure hypothesis 22 -- 1.6.4 Work flow and diagnostic information 22 -- 1.6.5 Key modeling assumptions 23 -- 1.6.6 Clinical validation 24 -- 1.7 Summary and conclusion 25 -- Appendix: Biomechanics Modeling 27 -- A.1 Definitions and terminology in statistics 27 -- 2 The circulatory system 29 -- 2.1 Physiology 29 -- 2.1.1 Vascular system 29 -- 2.1.2 Key concepts 31 -- 2.1.3 Cells in the vascular system 32 -- 2.1.4 Macrocirculation 33 -- 2.1.5 Lymphatic system 37 -- 2.1.6 Microcirculation 38 -- 2.1.7 Hemodynamic regulation 41 -- 2.2 Mechanical system properties 42 -- 2.2.1 Vascular pressure 43 -- 2.2.2 Vascular flow 44 -- 2.2.3 Vascular resistance 45 -- 2.2.4 Transcapillary transport 45 -- 2.3 Modeling the macrocirculation 45 -- 2.3.1 Windkessel (WK) models 46 -- 2.3.2 Vessel network modeling 57 -- 2.4 Modeling the Microcirculation 63 -- 2.4.1 Transcapillary concentration difference 63 -- 2.4.2 Filtration 65 -- 2.5 Summary and conclusion 70 -- Appendix: Mathematical preliminaries 72 -- A.1 Complex numbers 72 -- A.2 Fourier series approximation 72 -- Appendix: Basic circuit elements 73 -- B.1 Resistor element 73 -- B.2 Capacitor element 73 -- B.3 Inductor element 74 -- Appendix: Transport mechanisms 74 -- C.1 Diffusion 74 -- C.2 Advection 75 -- Appendix: Osmosis 75 -- D.1 Osmotic pressure 75 -- D.2 Transport across semipermeable membranes 76 -- 3 Continuum Mechanics 77 -- 3.1 Kinematics 78 -- 3.1.1 Deformation gradient 78 -- 3.1.2 Multiplicative decomposition 79 -- 3.1.3 Polar decomposition 79 -- 3.1.4 Deformation of the line element 79 -- 3.1.5 Deformation of the volume element 80 -- 3.1.6 Deformation of the area element 80 -- 3.1.7 Concept of strain 81 -- 3.2 Concept of stress 85 -- 3.2.1 Cauchy stress theorem 86 -- 3.2.2 Principal stresses 87 -- 3.2.3 Isochoric and volumetric stress 89 -- 3.2.4 Octahedral stress and von Mises stress 89 -- 3.2.5 Cauchy stress in rotated coordinates 91 -- 3.2.6 First Piola-Kirchhoff stress 91 -- 3.2.7 Second Piola-Kirchhoff stress 92 -- 3.2.8 Implication of material incompressibility on the stress state 93 -- 3.3 Material time derivatives 94 -- 3.3.1 Kinematic variables 94 -- 3.3.2 Stress rates 95 -- 3.3.3 Power-conjugate stress and strain rates 96 -- 3.4 Constitutive modeling 97 -- 3.4.1 Some mechanical properties of materials 97 -- 3.4.2 Linear elastic material 100 -- 3.4.3 Hyperelasticity 102 -- 3.4.4 Viscoelasticity 105 -- 3.5 Governing laws 113 -- 3.5.1 Mass balance 114 -- 3.5.2 Balance of linear momentum 116 -- 3.5.3 Maxwell transport and localization 118 -- 3.5.4 Thermodynamic principles 119 -- 3.6 General principles 125 -- 3.6.1 Free body diagram 125 -- 3.6.2 Initial Boundary Value Problem 126 -- 3.6.3 Principle of Virtual -- 3.7 Damage and failure 129 -- 3.7.1 Physical consequences 129 -- 3.7.2 Strain localization 130 -- 3.7.3 Linear Fracture Mechanics 132 -- 3.7.4 J -- Integral 133 -- 3.7.5 Cohesive zone modeling 133 -- 3.8 Multiphasic continuum theories 134 -- 3.8.1 Mixture theory 134 -- 3.8.2 Poroelasticity theory 134 -- 3.9 Summary and conclusion 135 -- Appendix: Mathematical preliminaries 136 -- A.1 Laplace and Fourier transforms 136 -- A.2 Matrix algebra 136 -- A.2.1 Trace of a matrix 137 -- A.2.2 Identity matrix 137 -- A.2.3 Determinant of a matrix 137 -- A.2.4 Inverse and orthogonal matrix 138 -- A.2.5 Linear vector transform 138 -- A.2.6 Eigenvalue problem 138 -- A.2.7 Relation between the trace and the eigenvalues 139 -- A.2.8 Cayley-Hamilton theorem 139 -- A.3 Vector algebra 140 -- A.3.1 Basic vector operations 140 -- A.3.2 Coordinate transformation 142 -- A.4 Tensor algebra 144 -- A.4.1 Spherical tensor 144 -- A.4.2 Tensor operations 145 -- A.4.3 Invariants of second-order tensors 145 -- A.5 Vector and tensor calculus 146 -- A.5.1 Local changes of field variables 146 -- A.5.2 Divergence theorem 147 -- Appendix: Some useful Laplace and Fourier transforms 148 -- B.1 Laplace transforms 148 -- B.2 Fourier transforms 150 -- Appendix: Some useful tensor relations 151 -- 4 Conduit vessels 153 -- 4.1 Histology and morphology of the vessel wall 154 -- 4.1.1 Layered vessel wall organization 154 -- 4.1.2 Differences between arteries and veins 155 -- 4.1.3 Extra Cellular Matrix (ECM) 156 -- 4.1.4 Cells 157 -- 4.2 Mechanical properties and experimental observations 158 -- 4.2.1 Aorta 160 -- 4.2.2 Carotid artery 161 -- 4.2.3 Coronary artery 162 -- 4.2.4 Iliac artery 163 -- 4.3 Vascular diseases 163 -- 4.3.1 Diagnostic examinations 164 -- 4.3.2 Atherosclerosis 165 -- 4.3.3 Biomechanical factors in atherosclerosis 167 -- 4.3.4 Carotid artery disease 169 -- 4.3.5 Coronary heart disease 171 -- 4.3.6 Aneurysm disease 172 -- 4.4 Vascular adaptation 174 -- 4.5 Constitutive descriptions 175 -- 4.5.1 Capacity of a vessel segment 176 -- 4.5.2 Hyperelasticity for incompressible solids 177 -- 4.5.3 Purely phenomenological descriptions 178 -- 4.5.4 Histo-mechanical descriptions 183 -- 4.5.5 General theory of fibrous connective tissue 185 -- 4.5.6 Residual stress and load -- free configuration 188 -- 4.5.7 Visco-elastic descriptions 189 -- 4.5.8 Damage and failure descriptions 191 -- 4.5.9 Non-passive vessel wall properties 194 -- 4.6 Identification of constitutive parameters 194 -- 4.6.1 Analytical vessel wall models 197 -- 4.6.2 Optimization problem 199 -- 4.7 Case study: Wall stress analysis of the normal and aneurysmatic -- infrarenal aorta 205 -- 4.7.1 the analysis type 205 -- 4.7.2 Setting the boundary conditions- Dirichlet boundary 205 -- 4.7.3 Setting the loading conditions - Neuman boundary 205 -- 4.7.4 Setting the vascular wall properties 206 -- 4.7.5 Setting the output options 206 -- 4.8 Summary and Conclusion 206 -- Appendix: Protocol experimental vessel wall testing 208 -- A.1 Tissue harvesting and sample preparation 208 -- A.2 Test protocol definition and data recording 208 -- A.3 Acquired -- x CONTENTS -- 5 Blood flow 211 -- 5.1 Blood composition 211 -- 5.1.1 Erythrocyte (or red blood cell) 212 -- 5.1.2 Leukocyte (or white blood cell) 212 -- 5.1.3 Thrombocyte (or platelet) 213 -- 5.1.4 Plasma 213 -- 5.2 Forces acting at blood particles 214 -- 5.2.1 Drag force 214 -- 5.2.2 Gravitational and inertia forces 214 -- 5.2.3 Forces related to fluid pressure 214 -- 5.2.4 Forces related to fluid velocity and shear stress 215 -- 5.2.5 Forces arising from collisions 216 -- 5.2.6 Chemical and electrical forces 216 -- 5.2.7 Segregation of blood particles 218 -- 5.3 Blood rheology modeling 218 -- 5.3.1 Alteration of blood microstructure with the shear rate 218 -- 5.3.2 Modeling generalized Newtonian fluids 219 -- 5.3.3 Single-phase viscosity models for blood 220 -- 5.3.4 Composition-based viscosity models for blood 221 -- 5.4 Blood damage 224 -- 5.5 Description of incompressible flows 224 -- 5.5.1 Energy conservation 224 -- 5.5.2 Linear momentum conservation 226 -- 5.6 Blood flow phenomena 232 -- 5.6.1 Laminar and turbulent flow 232 -- 5.6.2 Boundary layer flow 233 -- 5.6.3 Blood flow through circular tubes 233 -- 5.6.4 Multi-dimensional flow phenomena 234 -- 5.7 Case study: Wall Shear Stress (WSS) analysis of the normal and -- aneurysmatic infrarenal aorta 236 -- 5.7.1 Setting the analysis type 236 -- 5.7.2 Setting the boundary conditions -Dirichlet boundary 236 -- 5.7.3 Setting the loading conditions -Neuman boundary 237 -- 5.7.4 Setting the blood rheological properties 237 -- 5.7.5 Setting the output options 237 -- 5.8 Summary and conclusion 238 -- Appendix: Mathematical preliminaries 239 -- 6 The vascular wall, an active entity 241 -- 6.1 Vasoreactivity 242 -- 6.1.1 Structure of contractile SMC 242 -- 6.1.2 SMC contraction regulation 243 -- 6.2 Arteriogenesis 243 -- 6.3 Angiogenesis 244 -- 6.4 Damage, healing and failure 244 -- 6.5 Modeling frameworks 244 -- 6.5.1 Open system governing laws 245 -- 6.5.2 Kinematics-based growth description 246 -- 6.5.3 Tensorial distribution of volume growth 248 -- 6.5.4 Homeostatic growth 249 -- 6.5.5 Continues turnover-based growth description 252 -- 6.5.6 Other formulations 256 -- 6.5.7 Applications of growth descriptions 257 -- 6.6 Conclusion and Discussion 258 -- 6.7 Applications 259 -- 6.7.1 Tensile testing the passive and active vessel wall 259 -- 6.7.2 Biaxially loaded vessel wall patch 260 -- 6.7.3 Ring testing of vessel segments 262 -- References 265 -- Problem Solutions 287 -- Index 373.
    Abstract: This textbook serves as a modern introduction to vascular biomechanics and provides the comprehensive overview of the entire vascular system that is needed to run successful vascular biomechanics simulations. It aims to provide the reader with a holistic analysis of the vascular system towards its biomechanical description and includes numerous fully through-calculated examples. Various topics covered include vascular system descriptions, vascular exchange, blood vessel mechanics, vessel tissue characterization, blood flow mechanics, and vascular tissue growth and remodeling. This textbook is ideally suited for students and researchers studying and working in classical and computational vascular biomechanics. The book could also be of interest to developers of vascular devices and experts working with the regulatory approval of biomedical simulations. Follows the principle of “learning by doing” and provides numerous fully through-calculated examples for active learning, immediate recall, and self-examination; Provides a holistic understanding of vascular functioning and the integration of information from different disciplines to enable students to use sophisticated numerical methods to simulate the response of the vascular system; Includes several case studies that integrate the presented material. Case studies address problems, such as the biomechanical rupture risk assessment of Abdominal Aortic Aneurysms, Finite Element analysis of structural and blood flow problems, the computation of wall stress and wall shear stress in the aorta.
    Type of Medium: Online Resource
    Pages: XXIII, 608 p. 283 illus., 271 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030709662
    DDC: 571.43
    Language: English
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  • 49
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Genomic Improvement of Rice for Drought, Aluminum, and Iron Toxicity Stress Tolerance -- Advances In Breeding For Abiotic Stress Tolerance in Wheat -- Resistance to Abiotic Stress: Theory and Applications in Maize Breeding -- Genetic Diversity for Barley Adaptation to Stressful Environments -- Advances in Genomic Designing for Abiotic Stress Tolerance in Sorghum -- Genomic Designing for Abiotic Stress Tolerance in Pearl Millet -- Genomic Designing for Abiotic Stress Tolerance in Foxtail millet -- Genomic-Assisted Breeding in Finger Millet.
    Abstract: This book presents abiotic stresses that cause crop damage in the range of 6-20%. Understanding the interaction of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., is important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in cereal crops is imperative for addressing FPNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has facilitated precise information about the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a cereal crop in this volume are deliberate on different types of abiotic stresses and their effects on and interaction with crop plants; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; are brief on the classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; elucidate on the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different emerging genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Type of Medium: Online Resource
    Pages: XXIV, 317 p. 24 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030758752
    DDC: 580
    Language: English
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  • 50
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Economic Importance, Practical Limitations to Production, Management and Breeding Targets of Alfalfa -- Chapter 2. Factors Influencing Yield and Quality -- Chapter 3. The Origin, Evolution and Genetic Diversity of Alfalfa -- Chapter 4. Germplasm Collection, Genetic Resources and Gene Pools in Alfalfa -- Chapter 5. Biotechnology Advances in Alfalfa -- Chapter 6. Sequencing, Assembly and Annotation of the Alfalfa Genome -- Chapter 7. Transcription Factors in Alfalfa (Medicago sativa L.): Genome-Wide Identification and a Web Resource Center AlfalfaTFDB -- Chapter 8. Genomics of Forage Quality in Alfalfa -- Chapter 9. Physiological, Morphological, Biochemical, and Genetic Responses of Alfalfa to Salinity -- Chapter 10. Developing SNPs and Strategies for Genomic Analysis in Alfalfa -- Chapter 11. Genomics Resources for Breeding in Alfalfa: Availability, Utility, and Adoption -- Chapter 12. Genomic Selection for Higher Yield and Quality in Alfalfa -- Chapter 13. Identification and Characterization of Disease Resistance Genes in Alfalfa and Medicago truncatula for Breeding Improved Cultivars -- Chapter 14. Genetic and Genomic Assessments for Improving Drought Resilience in Alfalfa -- Chapter 15. Self-Incompatibility, Inbreeding Depression, and Potential to Develop Inbred Lines in Alfalfa -- Chapter 16. Targeted Mutagenesis of Alfalfa.
    Abstract: This book is the first comprehensive compilation of deliberations on whole genome sequencing of the diploid and tetraploid alfalfa genomes including sequence assembly, gene annotation, and comparative genomics with the model legume genome, functional genomics, and genomics of important agronomic characters. Other chapters describe the genetic diversity and germplasm collections of alfalfa, as well as development of genetic markers and genome-wide association and genomic selection for economical important traits, genome editing, genomics, and breeding targets to address current and future needs. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, breeding, pathology, physiology, molecular genetics and breeding, biotechnology, and structural and functional genomics. The work is also useful to seed and forage industries.
    Type of Medium: Online Resource
    Pages: XXV, 283 p. 64 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030744663
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 51
    Keywords: Botanical chemistry. ; Alternative medicine. ; Biotechnology. ; Agricultural biotechnology. ; Biomaterials. ; Food science. ; Plant Biochemistry. ; Complementary and Alternative Medicine. ; Biotechnology. ; Agricultural Biotechnology. ; Plant Materials. ; Food Engineering.
    Abstract: Before the concept of history began, humans undoubtedly acquired life benefits by discovering medicinal and aromatic plants (MAPs) that were food and medicine. Today, a variety of available herbs and spices are used and enjoyed throughout the world and continue to promote good health. The international market is also quite welcoming for MAPs and essential oils. The increasing environment and nature conscious buyers encourage producers to produce high quality essential oils. These consumer choices lead to growing preference for organic and herbal based products in the world market. As the benefits of medicinal and aromatic plants are recognized, these plants will have a special role for humans in the future. Until last century, the production of botanicals relies to a large degree on wild-collection. However, the increasing commercial collection, largely unmonitored trade, and habitat loss lead to an incomparably growing pressure on plant populations in the wild. Therefore, medicinal and aromatic plants are of high priority for conservation. Given the above, we bring forth a comprehensive volume, “Medicinal and Aromatic Plants: Healthcare and Industrial Applications”, highlighting the various healthcare, industrial and pharmaceutical applications that are being used on these immensely important MAPs and its future prospects. This collection of chapters from the different areas dealing with MAPs caters to the need of all those who are working or have interest in the above topic.
    Type of Medium: Online Resource
    Pages: XIV, 783 p. 10 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030589752
    DDC: 572.2
    Language: English
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  • 52
    Keywords: Agricultural biotechnology. ; Nanobiotechnology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Agricultural Biotechnology. ; Nanobiotechnology. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Preface -- Biobased Nanotechnology for Green Applications -- Characterization and Biocompatibility of a Poly Lactic Acid (PLA) 3D-Printed Scaffold -- Implications of Nanoscopic Surface Modification on Protein Adsorption and Cell Adhesion -- Biosurfactant-Based Nanoscale Micelles Extraction of Bio-Molecules -- Nanoemulsion of Herbal Bioactives -- Current Aspects of Nanotechnology in Agriculture -- Novel Strategies for Environmental Remediation of Pesticides Using Nano-Catalysts -- Bio-Nanoconjugates for Their Potential Role in Medical Science and Pharmaceuticals -- Enzymes in Nanoemulsion: A Way Forward for the Bioremediation of Organopollutants -- Biochar-Based Nanocomposites: A Sustainable Solution for Wastewater Treatment -- Bacteriocins as Nanoparticle Forms and Their Applications -- Dry Deposition of Atmospheric Nanoparticles -- Carbon Dots and Their Theranostic Applications -- Magnetic Nanoparticlles from Bacteria -- Exploring the Protective Efforts of Silver Nanoparticles as Bionanofungicide Against Soil-Borne Sclerotium rolfsii Infection in Wheat Plants -- A Green Synthetic of Magnetite Nanoparticles to Treat Heavy Metal Stress in Oryza sativa L. -- Synthesis of Novel Metal/Metal Oxide-Based Nanomaterials Using Plant Sources and Their Potential Environmental Applications -- Structural Model and Diagram Electro-Magnetoelastic Actuator for Nanobiotechnology -- Bionanocomposites for Green Applications -- Importance of Nanotechnologies in Changing Climatic Conditions -- Nanotechnology for Biofuels: Progress and Pitfalls -- Metal Organic Framework Nanomaterials -- Nanobubble Liposome Complexes: Significance in Diagnostic Imaging and Ultrasound-Triggered Drug Delivery -- Benefits of Chitosan-Based and Cellulose-Based Nanocomposites in Food Protection and Food Packaging -- Index.
    Abstract: Investigation on biobased nanomaterials has provided new insights into the rapidly advancing fields of the biomedical and environmental sciences by showing how these nanomaterials are effective in biomedicine and environmental remediation. These particles hold tremendous prospective applications, and are likely to become the next generation of particles in these areas. As such, research is ongoing and the data generated should have the potential for a sustainable future in both the environmental and biomedical fields. This book presents important findings on the role of and identification of novel applications of biobased nanomaterials. Unlike other books in this field, this book focuses entirely on sustainable application and remediation in biomedicine and environmental science. The chapters are written in such a way as to make them accessible to the reader, and furthermore, the volume can be readily adopted as a reference, or used as a guide for further research. This project was based on recent research (the last 5 years) and developed through an extensive literature search. The editors have also compiled some advanced, outstanding texts that should be of benefit to graduate students in their research.
    Type of Medium: Online Resource
    Pages: XX, 668 p. 89 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030619855
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 630
    Language: English
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  • 53
    Keywords: Biotechnology. ; Microbiology. ; Chemical engineering. ; Agricultural genome mapping. ; Biomaterials. ; Biotechnology. ; Microbiology. ; Chemical Process Engineering. ; Agricultural Genetics. ; Plant Materials.
    Description / Table of Contents: Methods for hemicellulose deconstruction aiming to xylose recovery: Recent progress and future perspectives -- Detoxification of hemicellulosic hydrolysates for improved xylitol production -- Fermentative production of xylitol from various lignocellulosic hydrolysates -- Strain improvement methods for enhanced xylitol production -- Fermentative methods for xylitol production: a comparative account on batch, fed-batch and continuous fermentation -- Methods for xylitol recovery: appraisal and future perspectives -- Critical analysis on xylitol production employing integrated approaches in sugarcane and corn processing mills -- Techno-economic analysis of xylitol production in standalone and integrated biorefineries -- Applications of xylitol in food, health and medical sector -- Market, consumption trends and commercial status of xylitol production.
    Abstract: This book explores recent advances in the microbial production of xylitol and its applications in food and medical sector. Xylitol is an important biomolecule from lignocellulose biorefinery which is produced from the xylose by chemical reactions or microbial fermentation methods. Currently, the demand of xylitol at commercial scale is being met through chemical methods. However, recent breakthroughs made in plant cell wall destruction, genetic engineering to develop the designer microorganisms, fermentation methods and media formulations and downstream processing have led the ways for sustainable production of xylitol at commercial scale in lignocellulose biorefineries. Microbial production of xylitol is preferred over the chemical processes as it is environmentally friendly, higher process efficiency with the desired product yield, and product recovery with minimum impurities. This book is a unique compilation of 11 book chapters written by experts in their respective fields. These chapters present critical insights and discuss the current progress and future progress in this area into fermentative xylitol production. Chapter 9 is licensed under the terms of the Creative Commons Attribution 4.0 International License. For further details see license information in the chapter.
    Type of Medium: Online Resource
    Pages: XII, 251 p. 40 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031049422
    DDC: 660.6
    Language: English
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  • 54
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Tomato -- Potato -- Capsicums -- Eggplant -- Vegetable Brassica -- Cucurbits -- Allums -- Amaranth.
    Abstract: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in vegetable crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a vegetable crop or crop group in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops.
    Type of Medium: Online Resource
    Pages: XXIII, 324 p. 16 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031039645
    DDC: 580
    Language: English
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  • 55
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Regenerative medicine. ; Veterinary medicine. ; Animal biotechnology. ; Biomedical engineering. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Veterinary Science. ; Animal Biotechnology. ; Biomedical Engineering and Bioengineering. ; Biotechnology.
    Abstract: Do cephalopods change color when under distress? Is the reptilian heart analogous to a diaphragm positive displacement pump? Are digital twins the answer for animal experimentation? This book explores the new field of veterinary engineering science and discusses how to better measure vital signs in exotic and companion animals. A vast opportunity exists for developing novel technologies that target reductions to the number of invasive procedures patients are subjected to. We examine improvements to animal care and enhancement of animal welfare while creating a more sustainable veterinary healthcare ecosystem. The authors address the challenges engineers face in designing healthcare equipment for animals and how the field of veterinary engineering contributes to traditional veterinary medicine. This book brings a novel field of engineering to train future veterinarians and engineers on design and application of technology to veterinary medicine.
    Type of Medium: Online Resource
    Pages: XI, 156 p. 25 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031228056
    DDC: 612.028
    Language: English
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  • 56
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Microbiology. ; Biotechnology. ; Evolution (Biology). ; Biomaterials. ; Nucleic acids. ; Cytology. ; Microbiology. ; Biotechnology. ; Evolutionary Biology. ; Nucleic Acid. ; Cell Biology.
    Description / Table of Contents: Reduced and Minimal Cell Factories in Bioprocesses: Towards a Streamlined Chassis -- Construction of minimal genomes and synthetic cells -- Engineering reduced-genome strains of Pseudomonas putida for product valorization -- Genome-reduced Corynebacterium glutamicum fit for biotechnological applications -- Reduction of the Saccharomyces cerevisiae genome: challenges and perspectives -- The use of in silico genome-scale models for the rational design of minimal cells -- From minimal to minimized genomes: Functional design of microbial cell factories -- Resource allocation principles and minimal cell design.
    Abstract: This book provides a comprehensive overview of the design, generation and characterization of minimal cell systems. Written by leading experts, it presents an in-depth analysis of the current issues and challenges in the field, including recent advances in the generation and characterization of reduced-genome strains generated from model organisms with relevance in biotechnology, and basic research such as Escherichia coli, Corynebacterium glutamicum and yeast. It also discusses methodologies, such as bottom-up and top-down genome minimization strategies, as well as novel analytical and experimental approaches to characterize and generate minimal cells. Lastly, it presents the latest research related to minimal cells of serveral microorganisms, e.g. Bacillus subtilis. The design of biological systems for biotechnological purposes employs strategies aimed at optimizing specific tasks. This approach is based on enhancing certain biological functions while reducing other capacities that are not required or that could be detrimental to the desired objective. A highly optimized cell factory would be expected to have only the capacity for reproduction and for performing the expected task. Such a hypothetical organism would be considered a minimal cell. At present, numerous research groups in academia and industry are exploring the theoretical and practical implications of constructing and using minimal cells and are providing valuable fundamental insights into the characteristics of minimal genomes, leading to an understanding of the essential gene set. In addition, research in this field is providing valuable information on the physiology of minimal cells and their utilization as a biological chassis to which useful biotechnological functions can be added.
    Type of Medium: Online Resource
    Pages: VII, 230 p. 35 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030318970
    DDC: 579
    Language: English
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  • 57
    Keywords: Microbial ecology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Hydrology. ; Sustainability. ; Biotic communities. ; Microbial Ecology. ; Environmental Engineering/Biotechnology. ; Water. ; Sustainability. ; Ecosystems.
    Description / Table of Contents: Preface -- Foreword -- 1. Concerns and Threats of Contamination on Aquatic Ecosystems -- 2. Effect of Pesticides on Fish Fauna: Threats, Challenges and Possible Remedies -- 3. Impact of Invasive Plants in Aquatic Ecosystems -- 4. Role of Modern Innovative Techniques for Assessing and Monitoring Environmental Pollution -- 5. Global Scenario of Remediation Techniques to Combat Environmental Pollution -- 6. Biopesticides: clean and viable technology for healthy environment -- 7. Inoculum addition in the presence of plant rhizosphere for petroleum polluted soil remediation -- 8. Vermicomposting: An Eco-friendly Approach for Recycling /Management of Organic Wastes -- 9. Bio-Fertilizers: Ecofriendly Approach for Plant and Soil Environment -- 10. Phytoremediation of heavy metals: an ecofriendly and sustainable approach -- 11. Credibility of in situ Phytoremediation for Restoration of Disturbed Environments -- 12. Role of White Willow (Salix alba L.) for Cleaning up the Toxic Metal Pollution -- 13. Mycoremediation: a Sustainable Tool for Abating Environmental Pollution -- 14. Microbial Biofilm Cell Systems for Remediation of Wastewaters -- 15. Pollution remediation by way of using genetically modified plants (GMP) -- Index.
    Abstract: Toxic substances threatens aquatic and terrestrial ecosystems and ultimately human health. The book is a thoughtful effort in bringing forth the role of biotechnology for bioremediation and restoration of the ecosystems degraded by toxic and heavy metal pollution. The introductory chapters of the book deal with the understanding of the issues concerned with the pollution caused by toxic elements and heavy metals and their impacts on the different ecosystems followed by the techniques involved in monitoring of the pollution. These techniques include use of bio-indicators as well as modern techniques for the assessment and monitoring of toxicants in the environment. Detailed chapters discussing the role of microbial biota, aquatic plants, terrestrial plants to enhance the accumulation efficiency of these toxic and heavy metals are followed by remediation techniques involving myco-remediation, bio-pesticides, bio-fertilizers, phyto-remediation and rhizo-filtration. A sizable portion of the book has been dedicated to the advanced bio-remediation techniques which are finding their way from the laboratory to the field for revival of the degraded ecosystems. These involve bio-films, micro-algae, genetically modified plants and filter feeders. Furthermore, the book is a detailed comprehensive account for the treatment technologies from unsustainable to sustainable. We believe academicians, researchers and students will find this book informative as a complete reference for biotechnological intervention for sustainable treatment of pollution.
    Type of Medium: Online Resource
    Pages: XVIII, 327 p. 47 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030356910
    DDC: 579.17
    Language: English
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  • 58
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Nanotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Genetics. ; Biotechnology. ; Nanotechnology. ; Microsystems and MEMS. ; Genetics and Genomics. ; Chemical Bioengineering.
    Description / Table of Contents: Introduction: DNA basics (a primer on DNA) -- Hiding and storing messages and data in DNA -- DNA as a nanoscale building material -- DNA machines and nanobots -- DNA-based nanoelectronics -- Concluding remarks.
    Abstract: This is the first book portraying to a wide readership many fields of DNA in the world of materials altogether in a single volume. The book provides underlying concepts and state-of-art developments in the emerging fields of DNA electronics, structural DNA nanotechnology, DNA computing and DNA data storage, DNA machines and nanorobots. Future possibilities of innovative DNA-based technologies, such as DNA cryptography, DNA identity tags, DNA nanostructures in biosensing and nanomedicine, as well as DNA-based nanoelectronics are all covered, too. This book is valuable for university students studying engineering and technology; biotech, nanotech, and medical device R&D managers, practitioners and investors; and IP analysts who would like to extend their background in advanced DNA technologies. It is nicely illustrated, which makes it very readable, and it conveys science and principles in a lively language to appeal to a broad audience, from professionals and academics to students and lay readers. Advance Praise for DNA Beyond Genes: “Most students of DNA, and lay readers as well, are interested in the absolutely essential role it plays in biology. However, the properties which make DNA the carrier of genetic information also make it an extraordinary material that can be used as the backbone for a wide variety of nanoengineering applications – these range from information storage and computation to molecular machines and devices to artfully designed logos and symbols. The perfect self-recognition of DNA sequences makes it an ideal building block to synthesize more and more elaborate constructions and imaginative scientists have probably only just scratched the surface of what can eventually be created. Here for the first time in this wonderful book Vadim Demidov explores the full range of the non-biological applications of DNA.” Charles R. Cantor Professor Emeritus of Biomedical Engineering, Boston University Member of the USA National Academy of Sciences.
    Type of Medium: Online Resource
    Pages: XX, 107 p. 66 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030364342
    DDC: 660.6
    Language: English
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  • 59
    Keywords: Biotechnology. ; Biomaterials. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Insights into the emergence, clinical prevalence and significance of Staphylococcus aureus small colony variants -- Periprosthetic Joint Infection -- Complications in orthopedic trauma surgery: fracture related infection -- Chiral Stereochemical Strategy for Antimicrobial Adhesion -- Perspectives on and need to develop new infection control strategies -- Battling bacteria with free and surface-immobilized polymeric nanostructures -- Engineering Approaches to Create Antibacterial Surfaces on Biomedical Implants and Devices -- 3D Printed Ceramic-Polymer Composites for Treating Bone Infection -- Bioinspired interfaces for the management of skin infections -- Antimicrobial endodontic materials -- Local Delivery of Anti-biofilm Therapeutics -- Device-Related Infections -- Advances in polysaccharide based antimicrobial delivery vehicles -- Antibacterial Coatings on Medical Implants -- Perspectives on biomaterial-associated infection: pathogenesis and current clinical demands -- Polymeric Nanoparticulate Delivery Vehicles of Antimicrobials for Biofilm Eradication -- Pathogenesis of biomaterial-associated infection -- Metal- and Polymer-Based Nanoparticles for Advanced Therapeutic and Diagnostic System Applications -- Antimicrobial Material in Arthroplasty -- Antimicrobial Hydrogels: Key Considerations and Engineering Strategies for Biomedical Applications -- Antibacterial Polymeric and Peptide Gels/Hydrogels to Prevent Biomaterial-related Infections -- The Impact of Bacterial Biofilms in Transfusion Medicine -- Mechanisms of Action and Chemical Origins of Biologically Active Antimicrobial Polymers -- When the Race is Lost: The Clinical Impact of Prosthetic Joint Infections -- Antibacterial Hydroxyapatite: An Effective Approach to Cure Infections in Orthopedics -- Index.
    Abstract: This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.
    Type of Medium: Online Resource
    Pages: XI, 650 p. 158 illus., 122 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030344757
    DDC: 660.6
    Language: English
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  • 60
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Microbiology. ; Microbial ecology. ; Botany. ; Biotechnology. ; Refuse and refuse disposal. ; Physical geography. ; Microbiology. ; Microbial Ecology. ; Plant Science. ; Biotechnology. ; Waste Management/Waste Technology. ; Earth System Sciences.
    Description / Table of Contents: Part 1. Composting: Paradigms and Mechanisms -- 1. Compost and Compost Tea Microbiology: the “-Omics” Era -- 2. Biological Sterilisation, Detoxification and Stimulation of Cucurbitacin-containing Manure -- 3. Nematode succession during composting process -- 4. Review on Physiological Effects of Vermicomposts on Plants -- 5. Interaction of Earthworm Activity with Soil Structure and Enzymes -- 6. Survival of Pathogenic and Antibiotic Resistant Bacteria in Vermicompost, Sewage Sludge and other Types of Composts in Temperate Climate Conditions -- Part 2. Modern Tools and Techniques for Composting Research -- 7. Molecular Tools and Techniques for Understanding the Microbial Community Dynamics of Vermicomposting -- 8. Molecular Tools and Techniques for Understanding the Microbial Community Dynamics of Vermicomposting -- 9. Recent Advances in Assessing the Maturity and Stability of Compost -- 10. Application of Nanotechnology to Research on the Microbiology of Composting -- Part 3. Composting Applications -- 11. Bioremediation of Pesticides in Soil Through Composting: Potential and Challenges -- 12. Current Trends and Insights on Compost Utilization Studies - Crop Residue Composting to Improve Soil Organic Matter in Sugarcane Cultivation, Tamil Nadu, India -- 13. Applications of Streptomyces spp. Enhanced Compost in Sustainable Agriculture.
    Abstract: This book highlights the latest findings on fundamental aspects of composting, the interaction of various microorganisms, and the underlying mechanisms. In addition to addressing modern tools and techniques used for composting research, it provides an overview of potential composting applications in both agriculture and environmental reclamation. Composting is the process of organic waste decomposition, mediated by microorganisms. The end-product is called ‘compost’ and can be used as a supplement to improve soil fertility. As the municipal waste generated in most developing countries contains a substantial amount of organic matter suitable for composting, this technology offers a win-win opportunity for stakeholders in terms of disposing of organic waste and providing organic fertilizers for agriculture. In addition, using compost reduces the dependency on harmful chemical fertilizers, and represents a sustainable and environmentally friendly alternative.
    Type of Medium: Online Resource
    Pages: XI, 291 p. 39 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030391737
    Series Statement: Soil Biology, 58
    DDC: 579
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Food Microbiology. ; Food science. ; Biotechnology. ; Biochemistry. ; Food Microbiology. ; Food Science. ; Biotechnology. ; Biochemistry.
    Description / Table of Contents: 1. History and Social Aspects of Sourdough -- 2. The sourdough legislation -- 3. Chemistry of Cereal Grains -- 4. Technology of Sourdough Fermentation and Sourdough Applications -- 5. Steamed Bread -- 6. Taxonomy and Biodiversity of Sourdough Lactic Acid Bacteria -- 7. Taxonomy, Biodiversity and Physiology of Sourdough Yeasts -- 8. Physiology and Biochemistry of Lactic Acid Bacteria -- 9. Sourdough: A Tool to Improve Bread Flavor, Rheology and Shelf Life -- 10. Sourdough: A Tool for Non-Conventional Fermentation and To Recover Side Streams -- 11. Nutritional Aspects of Cereal Fermentation with Lactic Acid Bacteria and Yeasts -- 12. Sourdough and Gluten-Free Products -- 13. Sourdough and Cereal Beverages -- 14. Perspectives.
    Abstract: Bread and leavened bakery products have been essential to human nourishment for millennia. Traditionally, bread production has relied on the use of sourdough as a leavening agent and to impart a characteristic quality to baked goods. In recent years, improved understanding of the biodiversity and microbial ecology of sourdough microbiota, the discovery of new species, the improved management and monitoring of its meta-community and the commercialization of innovative products have vastly expanded the potential of sourdough fermentation for making baked goods. For example, raw materials such as cereals, pseudo-cereals, ancient grains, and gluten-free substrates, as well as a large number of baked good varieties (e.g., typical and industrial breads, sweet baked goods, gluten-free products) may benefit from advances in sourdough fermentation. In addition, biotechnological tools and culture properties have been discovered to improve both the shelf life and the sensory and textural qualities of baked goods, as well as their nutritional and health-promoting properties. Now in its second edition, the Handbook on Sourdough Biotechnology remains the only book dedicated completely to sourdough biotechnology with the contribution of the most experienced researchers from the field. It reviews the history of sourdough and the potential of sourdough fermentation in the production of bread and baked goods. A thorough discussion of the various processing steps includes the chemical properties of the raw matter, the taxonomy, diversity, and metabolic properties of starter yeasts and lactic acid bacteria, and the effects of sourdough fermentation on the shelf life and the sensory, textural, nutritional, and health-promoting properties of baked goods.
    Type of Medium: Online Resource
    Pages: VI, 397 p. 47 illus., 26 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031230844
    DDC: 664.001579
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Cytology. ; Bioinformatics. ; Biology Technique. ; Biotechnology. ; Cell Biology. ; Computational and Systems Biology. ; Biological Techniques.
    Description / Table of Contents: Workflows and Components of Bioimage Analysis -- Measurements of Intensity Dynamics at the Periphery of the Nucleus -- 3D Quantitative Colocalisation Analysis -- The NEMO Dots Assembly: Single-Particle Tracking and Analysis -- Introduction to MATLAB: Image Analysis & Brownian Motion -- Resolving the process of Clathrin Mediated Endocytosis Using Correlative Light & Electron Microscopy (CLEM).
    Abstract: This Open Access textbook provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platforms such as ImageJ, MatLab and Python. Besides gaining knowhow on algorithm usage, readers will learn how to create an analysis pipeline by scripting language; these skills are important in order to document reproducible image analysis workflows. The textbook is chiefly intended for advanced undergraduates in the life sciences and biomedicine without a theoretical background in data analysis, as well as for postdocs, staff scientists and faculty members who need to perform regular quantitative analyses of microscopy images.
    Type of Medium: Online Resource
    Pages: X, 170 p. 69 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030223861
    Series Statement: Learning Materials in Biosciences,
    DDC: 660.6
    Language: English
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    Keywords: Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental policy. ; Sociology. ; Physical geography. ; Pollution. ; Microbiology. ; Environmental Engineering/Biotechnology. ; Environmental Policy. ; Sociology. ; Physical Geography. ; Pollution.
    Description / Table of Contents: Chapter 1 -- The importance of technogenesis and sustainable environmental protection technologies. Chapter 2 -- Natural and artificial biogeochemical barriers as natural technologies. Chapter 3 -- The sustainable natural materials and their role in waste management and soil contamination stabilizing. Chapter 4 -- The sustainable natural materials used for adsorbing contaminants from aqueous medium. Chapter 5 -- Biotechnologies as the sustainable environmental protection technologies. Chapter 6 -- The major properties of natural materials used in biofiltration systems. Chapter 7 -- Operational parameters of biofiltration systems required for efficient operation of components ensuring system’s sustainability. Chapter 8 -- Natural and inoculated microorganisms as important component for sustainability of biofiltration system. Chapter 9 -- The technologies of the sustainable environmental protection in real conditions in the case of biofiltration systems.
    Abstract: This book discusses the need for the development of sustainable environmental protection technologies to reduce the impact of environmental contaminants. Three levels of sustainable technologies are addressed. The first level involves the concept of sustainable technologies as natural technologies, or ecotechnologies, whereby contamination level is assessed based on the contamination footprint through the use of biogeochemical barriers (e.g. methods utilizing the bioaccumulation properties of plants). The second level concerns the use of sustainable natural materials, such as biochar, in environmental engineering systems, an approach that is used for analyzing the processes of adsorption and biofiltration, as well as immobilization of contaminants in soil. The third level discusses the optimal components necessary to achieve sustainability in environmental engineering systems, including system operation principles, structural solutions, and the synergies between various system components such as microorganisms. The book will be of interest to specialists of industrial enterprises engaged in environmental protection, as well as environmental system designers, stakeholders from environmental protection ministries and institutions, researchers, doctoral students and masters and bachelors of science in the field of environmental engineering.
    Type of Medium: Online Resource
    Pages: XXI, 645 p. 287 illus., 123 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030477257
    DDC: 579
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Genomics of Abiotic Stress Resistance in Malus domestica -- Genomic Designing for Abiotic Stress Resistant Banana -- Genetic Improvement of Citrus Limon (L. Burm f.) for Resistance to Mal Secco Disease -- Genomic Designing for Abiotic Stress Resistant Grapevine -- Wild and Related Species as a Breeding Source for Abiotic Stress Resistance of Peach Cultivars and Rootstocks -- Genomic Designing of new Almond-Peach Rootstock-variety Combinations Resistance to Plum pox virus -- Genomic Designing of New Plum Pox Virus Resistant Plumcot -- Integrated Genomic Designing and Insights for Disease Resistance and Crop Protection against Pathogens in Cherry -- Development of Abiotic Stress Tolerant Berries.
    Abstract: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in fruit crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing in many of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The seven chapters each dedicated to a fruit crop and a fruit crop group in this volume elucidate different types of abiotic stresses and their effects on and interaction with the crops; enumerate the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Type of Medium: Online Resource
    Pages: XXII, 249 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031098758
    DDC: 580
    Language: English
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    Keywords: Biotechnology. ; Radiology. ; Biomedical engineering. ; Neurosciences. ; Biotechnology. ; Radiology. ; Biomedical Engineering and Bioengineering. ; Neuroscience.
    Description / Table of Contents: Electromagnetic Properties and the Basis for CDI, MREIT and EPT -- Modeling for Electromagnetic Characterization, Prediction and Reconstruction -- Magnetic Resonance Imaging Basics -- Phantom Construction and Equipment Configurations for Characterizing Electrical Properties using MRI -- MR Current Density and MREIT Data Acquisition -- Magnetic Resonance Current Density Imaging (MR-CDI) -- Magnetic Resonance Electrical Impedance Tomography -- Index.
    Abstract: This book covers the latest developments in tissue electrical conductivity and current density imaging, increasingly popular as well as challenging applications of MRI. These applications are enabled by the acquisition of high-quality MR phase images. This book provides a practical description of the MRI physics needed to understand and acquire phase images in MRI and the key details required to reconstruct them into conductivity, current density or electric field distributions. Comprehensive details are provided about the electrical properties of biological tissues, computational modeling considerations, experimental methods, construction of non-biological and biological phantoms and MRI pulse sequences. An inclusive review of image reconstruction algorithms, and their potential applications is provided for applications directed at determining current density or electric fields, such as in transcranial DC or AC stimulation techniques; as well as electrical conductivity reconstructions that may be of use in quantitative MRI applications used to detect cancer or other pathologies. This is an excellent book for undergraduate and graduate students beginning to explore phase, current density, and conductivity imaging in MRI, and will also be of great use to researchers interested in the area of MR-based electrical property imaging.
    Type of Medium: Online Resource
    Pages: VII, 206 p. 101 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031038730
    Series Statement: Advances in Experimental Medicine and Biology, 1380
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Biology Technique. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Biological Techniques. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Management of Biobanks -- Chapter 2. Quality Management -- Chapter 3. Documentation and Records -- Chapter 4. Human Resources Management -- Chapter 5. Ethical and Legal Aspects -- Chapter 6. Supplies, Materials Management -- Chapter 7. Equipment -- Chapter 8. Traceability -- Chapter 9. Environmental and Staff Hygiene -- Chapter 10. Biobanking Processes and Quality Control -- Chapter 11. Deviations, Nonconforming Product/Data or Service -- Chapter 12. Audits -- Chapter 13. Improvement -- Chapter 14. Biobank Cooperation in the Scientific, Research and Development Area -- Chapter 15. Safety and Security.
    Abstract: This pioneering handbook serves as an essential tool for any biobanking entity to create, implement and continuously improve their Quality Management System (QMS). Written in a concise and highly readable manner all biobanking related QMS aspects, ranging from legal aspects to safety matters, are addressed according to the best knowledge in compliance with the dedicated Biobanks ISO standards. Following a practical approach by making use of FAQ and common practice sections this book guides the readers through this complex field in an easy-to understand way. The guidelines are convergent not only with ISO 20387:2018 Biotechnology - Biobanking - General requirements for biobanking but also with ISO 9001:2015, ISO 19011:2018, ISO 27000:2014, and ISO 27002:2013. Furthermore, they are compatible, among others with the recommendations of the Organization for Economic Cooperation and Development (OECD), IARC, and ISBER Best Practices. Aimed at both biobank employees and other stakeholders (e.g. public bodies, political bodies, hospitals, pharmaceutical industry, funders) at any level of experience the book serves as valuable source for self-education and teaching. The manual complies to the principles of responsibility, openness, and transparency and can be used by any biobanking unit regardless of the biological material the biobank operates with and independent of their associated biobank network. On behalf of a group of specialists and experts in the area of biobanking, regarding Quality Management Systems (QMS), Ethical, Legal and Societal Issues (ELSI) and IT solutions, the authors present with this book a significant achievement based on activities within the project, European Research Infrastructure BBMRI-ERIC „Quality Standards for Polish Biobanks” Handbook (QSPB).
    Type of Medium: Online Resource
    Pages: XVII, 152 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031125591
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Teak: The King of Timbers -- Chapter 2. Teak Plantations and Wood Production -- Chapter 3. Modern Silvicultural Practices and Productivity of Teak -- Chapter 4. Analysis and Modeling of Teak growth: New Perspectives for Productivity Evaluation -- Chapter 5. Economics of Teak -- Chapter 6. Teak Biology and Ecology -- Chapter 7. Teak Wood Chemistry and Natural Durability -- Chapter 8. Wood Properties and their Variations in Teak -- Chapter 9. Seed Biology and Seed Orchard Dynamics in Teak -- Chapter 10. Clonal Teak -- Chapter 11. Clonal Characterization and Variety Registration of Teak -- Chapter 12. Genetic Diversity and Population Genetic Structure of Teak -- Chapter 13. Genetic Improvement of Teak -- Chapter 14. Molecular Physiology of Teak -- Chapter 15. Genome of Teak: Structure and Features -- Chapter 16. Functional Genomics of Teak. .
    Abstract: This book is the first comprehensive compilation of knowledge on teak biology, ecology, clonal forestry, clonal registration, seed biology, and seed orchards. The teak genetic diversity, the sequenced genome, and transcriptomes from different tissues and their implications in modern tree improvement and material selection have been comprehensively discussed. The book also presents a narrative on wood characterization, wood chemistry, modern silviculture, growth and modelling, and economics of this valued tropical species. Altogether, the book contains about 200 pages over 16 chapters authored by globally reputed experts on the relevant field in this tropical tree. This book is useful to students, teachers, and scientists, and wood-based industries are interested in forestry, biology, seed orchards, breeding, genetic diversity, molecular genetics, in vitro culture, wood chemistry, and structural and functional genomics.
    Type of Medium: Online Resource
    Pages: XXV, 265 p. 48 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030793111
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agriculture. ; Food science. ; Nutrition   . ; Environmental sciences Social aspects. ; Biotechnology. ; Agriculture. ; Food Science. ; Nutrition. ; Environmental Social Sciences. ; Biotechnology.
    Description / Table of Contents: 1. Harnessing the Hidden Treasures in African Yam Bean (Sphenostylis stenocarpa), An Underutilized Grain Legume with Food Security Potentials -- 2. The Role of Indigenous Food Species in Achieving Food Security in South-Eastern Nigeria -- 3. The potentials of African neglected and orphan crops in augmentation of African food security -- 4. Optimization of Soaking Condition and Drying Temperature for The Production of African Yam Beans (Sphenostylis sternocarpa) Flour -- 5. Harnessing the Potential of Underutilized Aquatic Bioresource For Food and Nutritional Security in Kenya -- 6. Exploring Some Neglected and Underutilized Root and Tuber Crops for Food Security in Nigeria -- 7. Finger Millet: A Crop with Food Security Potentials for Africans -- 8. An Exploratory Study of The Association Among Household Food Securing Activities, Gender and Health in South Africa -- 9. Exploring the Industrial Potential of The Nigerian Pumpkins (Cucurbita pepo L.) -- 10. Functional Meat and Meat Products for Sustainable African Nutrition Security -- 11. Agricultural Productivity: A Key Component of Inclusive Growth Towards Food Security -- 12. Optimal Formulation of a Composite Flour from Biofortified Cassava, Pigeonpea, and Soybean for Complementary Feeding -- 13. Gauging Food Insecurity Resilience Among Pastoral Communities: A Case Study of Kenya -- 14. Optimisation and Multiplication of Large Fulani Eco-Type Chicken for Sustainable Production and Genetic Security in Nigeria -- 15. Soil Quality Indicators; Their correlation and Role in Enhancing Agricultural Productivity -- 16. Soil Quality and Horticulture: Implication for Food Security and Safety in Nigeria -- 17. Beneficiation of castor and thorn trees as management strategy to food security -- 18. Soil Information as A Factor to Consider in Sustainable Tree Crop Production for Nutritional Security, Poverty Alleviation and Biodiversity Management in Africa -- 19. African Walnuts: A Natural Depository of Nutritional and Bioactive Compounds Essential for Food and Nutritional Security in Africa -- 20. Implications of Production, Post-harvest and Consumption of Fish on Food and Nutrition Security: Nigeria as a Focal Country -- 21. Improving Crop Physio-Biochemical Efficiency and Abiotic Resilient Crops for Alleviating Food Insecurity in Africa -- 22. Analysis of Cassava Farmers’ Response to Climate Change Adaptation: Implication for Sustainable Food Production in Nigeria -- 23. Sustainable Agriculture: A Way Out to Combat Food Insecurity and Unsafety in The Context of Climate Change in West Africa -- 24. Smart Crops for Climate Change and Food Security in Africa -- 25. Impact of Climate Change and Climate Variability on Food Safety and Occurrence of Foodborne Diseases -- 26. Management of Soil-Microorganism: Interphase for Sustainable Soil Fertility Management and Enhanced Food Security -- 27. The Relevance of Plant Breeding to Food Security in Africa -- 28. Extent, Impact and Prospects of Genetically Engineered Crops in Africa -- 29. Soil Microbes and Food Security Nexus: Imperativeness of Microbial Biotechnology -- 30. Production of Edible Oil from Microorganisms -- 31. Food Sustainability Enhancement: Plant Growth-Promoting Bacteria as Key Players in The Alleviation of Drought Stress in Plants -- 32. Molecular Markers: Potential Facilitators in Plant Breeding and Germplasm Conservation -- 33. Biofertilizer: An Eco-Friendly Approach for Sustainable Crop Production -- 34. Design and Development of a Hybrid Bio-Solar Energy Fruit Dryer -- 35. Advances in Extrusion Technology and Its Applicability to Food Processing in Developing Nations -- 36. Nanotechnology as Vehicle for Biocontrol of Plant Diseases in Crop Production -- 37. Fusarium Species and Their Associated Mycotoxins in Foods and Their Products In Africa -- 38. Application of Nanobiotechnology In Agri-Food Sector; A Promising Technique in Food Safety -- 39. Salmonella enterica Subspecies Enterica Serotypes Associated with Meat and Meat Products in African Countries: A Review -- 40. Heavy Metals Contamination of Arable Lands: A Threat to Food Security and Safety -- 41. A Step Forward Towards Food Safety from Parasite Infective Agents -- 42. African Fermented Food as Antimicrobial Agents -- 43. Risk Assessment of Human Carcinogenicity of Acrylamide in Food: Way to Reduce the Predicted Mitogenic Side Effects Through Mitigation Strategy -- 44. Safety Hazards Along Animal Food Supply Chain in Nigeria.
    Abstract: This book focuses on food security and safety issues in Africa; a continent presently challenged with malnutrition and food insecurity. The continuous increase in the human population of Africa will lead to higher food demands, and climate change has already affected food production in most parts of Africa, resulting in drought, reduced crop yields, and loss of livestock and income. For Africa to be food-secure, safe and nutritious food has to be available, well-distributed, and sufficient to meet people’s food requirements. Contributors to Food Security and Safety: African Perspectives offer solutions to the lack of adequate safe and nutritious food in sub-Saharan Africa, as well as highlight the positive efforts being made to address this lack through a holistic approach. The book discusses the various methods used to enhance food security, such as food fortification, fermentation, genetic modification, and plant breeding for improved yield and resistance to diseases. The authors emphasize the importance of hygiene and food safety in food preparation and preservation, and address how the constraints of climate change could be overcome using smart crops. As a comprehensive reference text, Food Security and Safety: African Perspectives seeks to address challenges specific to the African continent while enhancing the global knowledge base around food security, food safety, and food production in an era of rapid climate change. Professor Olubukola Oluranti Babalola (Pr.Sci.Nat, MASSAF) is the Vice President of the Organization for Women in Science for the Developing World, and a National Research Foundation rated established, scientist. She is the Research Director of Food Security and Safety at North-West University, Mmabatho, South Africa.
    Type of Medium: Online Resource
    Pages: XLVIII, 907 p. 123 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030506728
    DDC: 630
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. The Broomcorn Millet Genome -- Chapter 2. Buckwheat Genome and Genomics -- Chapter 3. Tef [Eragrostistis tef (Zucc.) Trotter] -- Chapter 4. The Apricot Genome -- Chapter 5. Chinese Jujube: Crop Background and Genome Sequencing -- Chapter 6. The Longan (Dimocarpus longan) Genome -- Chapter 7. The Mangosteen Genome -- Chapter 8. The Passion Fruit Genome -- Chapter 9. The Soursop Genome (Annona muricata L., Annonaceae) -- Chapter 10. Underutilised Fruit Tree Genomes from Indonesia -- Chapter 11. The Bambara Groundnut Genome: From the Crop to the Genome -- Chapter 12. Grasspea -- Chapter 13. The Lablab Genome -- Chapter 14. The Perennial Horse Gram (Macrotyloma axillare) Genome, Phylogeny, and Selection Across the Fabaceae -- Chapter 15. Breeding and Genomics of Pigeonpea in the Post-NGS Era -- Chapter 16. Rice Bean -- Chapter 17. The Winged Bean Genome: One Species Supermarket -- Chapter 18. Castor Bean: Recent Progress in Understanding the Genome of this Underutilized Crop -- Chapter 19. Genome Resources for Ensete Ventricosum (enset) and Related Species -- Chapter 20. Yam Genomics -- Chapter 21. The African Eggplant -- Chapter 22. Sequencing of the Bottle Gourd Genomes Enhances Understanding of the Ancient Orphan Crop -- Chapter 23. Advances and Prospects in Genomic and Functional Studies of the Aquatic Crop, Sacred Lotus -- Chapter 24. Utilising Public Resources for Fundamental Work in Underutilised and Orphan Crops.
    Abstract: This book highlights the uses for underutilized crops, presenting the state-of-the-art in terms of genome sequencing for over 30 crops, previously understudied and under-researched. In a changing climate and with significant pressure on the land, it is the ideal time to be discussing novel crops, with significant biotic and abiotic tolerances and/or rich nutrient profiles for consumers. Previously, the only species with sequenced genomes were high-profile internationally recognized crops, but in the current era genomes are being sequenced for dozens of crops, including those previously classified as underutilized, now being investigated. This book covers food crops, from fruits to tubers, and from grasses to legumes, as well as crops with non-food applications. Some of these crops have draft genomes, and others have polished genomes with extensive resequencing panels. Each chapter tells the story of an individual crop or crop group, written by experts, focusing on the genome data available, revealing more about crop domestication and genetic variation, and the current and future prospects given that this data is now becoming available. It also highlights how even small sequencing projects can provide draft genome sequences suitable for gene discovery, comparative genomics, and identification of molecular markers for understanding these crops further.
    Type of Medium: Online Resource
    Pages: XXIV, 450 p. 125 illus., 105 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031008481
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Biosystematics and Botanical Descriptions of Seabuckthorn (Hippophae Sp.) in India -- Genetic Diversity, Evolution and Biogeography of Seabuckthorn -- Current Status of Chromosome-based Gender Determination in Seabuckthorn -- Analytical Techniques for the Biochemical Profiling in Seabuckthorn -- Effect of Processing and Storage on Seabuckthorn Products -- Metabolomic Diversity of Seabuckthorn Collections from Different Geographical Regions -- Deciphering the Proteomes and Nanotechnological Potential of an Unexplored Plant Seabuckthorn -- Biotechnological Approaches for Seabuckthorn Improvement -- Repertoire of Molecular Markers and their Applications in Seabuckthorn -- Barcoding-based Identification of Hippophae species -- Transcriptome Sequencing and Analysis of Seabuckthorn (Hippophae Sp.) -- Mining of Microsatellites and Transcription Factors in Seabuckthorn (Hippophae Sp.) Transcriptomes -- Frankia – The Endo-micro-symbiont of Hippophae Sp -- Medicinal and Nutraceutical Properties of Seabuckthorn -- Molecular and Cellular Mechanisms of the Anti-oxidative Activity of Seabuckthorn (Hippophae rhamnoides L.) -- Knowing More About Seabuckthorn (Hippophae rhamnoides)- A Promising Source of Safe and Effective Medical Radiation Countermeasure -- Methods in Seabuckthorn Breeding -- Global Distribution of Seabuckthorn (Hippophae Sp.) Resources and their Utilization .
    Abstract: This work is the first compilation of comprehensive deliberations on botany, cytogenetics and sex determination, genetic resources and diversity, classical breeding, molecular markers and genome sequence resources, and application of omics technology including transcriptomics, proteomics, and metabolomics resources in the multipurpose medicinal plant seabuckthorn. The book also presents a detailed narrative on antioxidative, radioprotective nutraceutical, and medicinal applications of seabuckthorn products. A detailed treatment has been included on analytical techniques and processing technologies. Altogether, the book contains about 300 pages over 17 chapters contributed by globally reputed experts on the relevant field in this important plant species. This book will be useful to the research students, teachers, and scientists in the academia and private sector engaged in horticulture, genetics, breeding, molecular biology, biotechnology, and breeding. The book will also be a useful source for workers involved in the development of plant-based medicines, nutraceuticals, therapeutics, and cosmeceuticals and extension workers involved in the development of rural farmers and small-scale industries.
    Type of Medium: Online Resource
    Pages: XXIX, 368 p. 74 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031112768
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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    Keywords: Microbial ecology. ; Microbiology. ; Environment. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Sustainability. ; Microbial Ecology. ; Environmental Microbiology. ; Microbiology. ; Environmental Sciences. ; Environmental Engineering/Biotechnology. ; Sustainability.
    Description / Table of Contents: Chapter. 1. A diverse array of microbial taxa affianced in bioremediation to counteract environmental pollution.-Chapter. 2. Aerobic processes: best approach for the treatment of wheat starch effluents -- Chapter. 3. Banned pesticides with high persistence: the impact of their use in agriculture and their removal by microbial biodegradation -- Chapter. 4. Bioremediations for Oil Spills by Utilizing Microbes -- Chapter. 5. Genetically engineered microorganisms for bioremediation processes -- Chapter. 6. Microbial Modifications and Biochemical Pathway-mechanism for ecosystem decontamination -- Chapter. 7. Innovative biofilms mediated as empiricist of bioremediation for sustainable development -- Chapter. 8. Major groups of microorganisms employed in bioremediation -- Chapter. 9. Microbial Exploration and their Metabolic Capacity for detoxification and Restoration of Natural Ecosystems -- Chapter. 10. Microbes in Restoration of Polluted Ecosystems -- Chapter. 11. Microbial Biotechnology: Energy generation approach from the environmental waste -- Chapter. 12. Microbial degradation of industrial pollutants from different environment -- Chapter. 13. Microbial enzymes and their importance in the environmental decontamination -- Chapter. 14. Structural and Functional Dynamics of Bacterial-world for Sustainability -- Chapter. 15. Plant-Associated Bacteria in Ecosystems Functioning and Sustainability -- Chapter. 16. The science of microbial enzymes as detoxification tool for inorganic and organic pollutants.
    Abstract: Microbial bioremediation and biodegradation in environmental monitoring offers an environmentally friendly approach for the monitoring and effective removal of contaminants. Various aspects of microbial-mediated bioremediation take advantage of the microorganisms’ ability to transform noxious compounds into utilizable intermediates and value-added products. Different microbial metabolites such as enzymes, biosurfactants, emulsifiers, organic acids, and solvents play significant roles in the decontamination of radioactive and heavy metals, chemical pesticides, and organic contaminants such as dyes and hydrocarbons in environmentally safe manners. Recent advancements in biochemical engineering, OMICS and genetic modification, and synthetic-biology pave ways for identifying indicator microbial strains, mechanisms of remediation, and the development of tailor-made microbe-metabolites for future applications. Microbial biotechnology in environmental monitoring and bioremediation thus represent a new way to rehabilitate and reconstruct “damaged” ecosystems. This work summarizes the latest research in the field of environmental bioremediation and offers fascinating insights on the behaviours of these unique microorganisms. It also presents exciting, new perspectives for the application of microbes in environmental protection. It is suitable for students, scholars, researchers and organizations involved in environmental protection.
    Type of Medium: Online Resource
    Pages: XXIII, 303 p. 52 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031180170
    DDC: 579.17
    Language: English
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  • 72
    Keywords: Biotechnology. ; Biomaterials. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Part I: Innovative antimicrobial and osteoinductive therapeutics -- Advances in antimicrobial and osteoinductive biomaterials -- Recent Advances in Controlled Release Technologies for the Co-Delivery of Antimicrobial and Osteoconductive Therapeutics -- Biofilm-inhibiting and osseointegration-promoting orthopedic implants with novel nanocoatings -- Three dimensional (3D) and drug-eluting nanofiber coating for prosthetic implants -- Cationic antimicrobial coatings with osteoinductive properties -- Peptide Functionalized Biomaterials with Osteoinductive or Anti-biofilm Activity -- Construction of bio-functionalized ZnO coatings on titanium implants with both self-antibacterial and osteoinductive properties -- Gasotransmitters: antimicrobial properties and impact on cell growth for tissue engineering -- Carbon nanotubes: Their antimicrobial properties and applications in bone tissue regeneration -- Part II: Interface tissue engineering and advanced material for scaffolds -- Fracture healing and progress towards successful repair -- Animal models for bone tissue engineering and osteoinductive biomaterial research -- Bioprinting in Tissue Engineering -- Additive Manufacturing of Bio-scaffolds for Bone Regeneration -- Anti-biofouling and Antimicrobial Biomaterials for Tissue Engineering -- Osteoinductive and osteoconductive biomaterials -- Bimetallic nanoparticles for biomedical applications: a review -- Peptide-mediated Bone Tissue Regeneration -- Antibody mediated osseous regeneration - a new strategy for bioengineering -- Extracellular matrix-based materials for bone regeneration -- Calcium Phosphate Biomaterials for Bone Tissue Engineering: Properties and Relevance in Bone Repair -- Bioactive Glasses in Orthopedic Applications -- Advances in Tissue Engineering and Regeneration -- SCAFFOLDS FOR TISSUE ENGINEERING: A state of the art review concerning types, properties, materials, processing and characterization -- Recent Developments of Zn-Based Medical Implants -- Recent physical interaction-based bioadhesives -- Tellurium, the forgotten element: a review for the properties, processes and biomedical applications of the bulk and nanoscale metalloid -- Index.
    Abstract: This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.
    Type of Medium: Online Resource
    Pages: XI, 809 p. 152 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030344719
    DDC: 660.6
    Language: English
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  • 73
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Stem cells. ; Cancer Biology. ; Biomedical Research. ; Biotechnology. ; Stem Cell Biology.
    Description / Table of Contents: Preface -- Introduction – Biology of Breast Cancer Metastasis and Importance of the Analysis of CTCs -- Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis -- Disseminated Tumor Cells and Dormancy in Breast Cancer Progression -- Methodology for the Isolation and Analysis of CTCs -- Advances in the Characterization of Circulating Tumor Cells in Metastatic Breast Cancer: Single Cell Analyses and Interactions, and Patient-derived Models for Drug Testing -- Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs -- Relevance of CTC Clusters in Breast Cancer Metastasis -- Epigenetics of Circulating Tumor Cells in Breast Cancer -- Circulating Tumor Cells: Applications for Early Breast Cancer -- Clinical Relevance and Therapeutic Application of CTCs in Advanced Breast Cancer. .
    Abstract: This book compiles the latest research and key findings about the role of circulating tumor cells (CTCs) in Breast Cancer progression, both from the research and clinical standpoint. Based on latest advancements, the content of the book is set out to provide a clear overview about the biology and use of CTCs as a tool for the monitoring and management of breast cancer patients. This work covers basic concepts about the process of metastasis, the biology of CTCs and their potential applications as a biomarker in breast cancer. It will enable readers to delve into the process of epithelial-mesenchymal plasticity (EMP), mechanisms and clinical implications of tumor cell dormancy and minimal residual disease, and into the phenotypical and molecular heterogeneity of CTCs and CTC clusters, including the epigenetic characterization of CTCs. Readers will find out about the key technologies used for the isolation of CTCs as well as the latest advances towards the characterization of CTCs, involving single cell analyses and patient-derived models. It will discuss the evidences about the use of CTCs as a tool to monitor breast cancer progression and therapy response, as well as to unravel mechanisms of resistance to therapy and to identify new therapeutic targets favoring the development of novel anticancer drugs. Lastly, it will discuss ongoing clinical trials and try to foresee the future of CTCs in terms of clinical application and implementation in the clinical routine. The topic of this book is particularly relevant for cancer researchers and oncologist with an interest in the field, looking to refresh or to broaden their knowledge and understanding about the use of CTCs as a diagnostic biomarker in breast cancer.
    Type of Medium: Online Resource
    Pages: XV, 167 p. 15 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030358051
    Series Statement: Advances in Experimental Medicine and Biology, 1220
    DDC: 571.978
    Language: English
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  • 74
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Bioinformatics. ; Biotechnology. ; Computational and Systems Biology.
    Description / Table of Contents: Web-based 3D visualisation of biological and medical data -- Ultrasound-Guided Regional Anaesthesia: Visualising Nerve and Needle -- Scanning conditions in functional connectivity magnetic resonance imaging: how to standardise resting-state for optimal data acquisition and visualisation? -- Interactive VR Stroke Rehabilitation System Design -- Systematic review of Augmented and Virtual Reality in anatomical education -- Interdimensional travel: Visualisation of 3D-2D transitions in anatomy learning -- Anatomy Visualizations Using Stereopsis: Assessment and Implication of Stereoscopic Virtual Models in Anatomical Education -- Storyboarding in Medical Animation -- The hidden curriculum of imaging and utilisation of unregulated social media resources within clinical education -- Online distance learning in biomedical sciences: Community, belonging and presence. .
    Abstract: This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will be able to explore the utilisation of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences, with a focus in this volume related to anatomy, and clinically applied scenarios. The first eight chapters examine a variety of tools, techniques, methodologies and technologies which can be utilised to visualise and understand biological and medical data. This includes web-based 3D visualisation, ultrasound, virtual and augmented reality as well as functional connectivity magnetic resonance imaging, storyboarding and a variety of stereoscopic and 2D-3D transitions in learning. The final two chapters examine the pedagogy behind digital techniques and tools from social media to online distance learning techniques.
    Type of Medium: Online Resource
    Pages: XV, 181 p. 69 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030376390
    Series Statement: Advances in Experimental Medicine and Biology, 1235
    DDC: 660.6
    Language: English
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  • 75
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Stem cells. ; Biotechnology. ; Biomedical Research. ; Stem Cell Biology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. The historical studies underpinning the concept of hair follicle neogenesis (Higgins C, Jahoda C) -- Chapter 2. Hair regeneration and rejuvenation: pipeline of medical and technical strategies (Limbu S, Kemp P) -- Chapter 3. Cells and structures involved in hair follicle regeneration: an introduction (Tsai J, Garza LA) -- Chapter 4. The dermal papilla and hair follicle regeneration: Engineering strategies to improve dermal papilla inductivity (Pantelireis N, Clavel C) -- Chapter 5. Dermal sheath and hair follicle regeneration (Yoshida Y, Tsuboi K, Kishimoto J) -- Chapter 6. Epithelial-mesenchymal interactions between hair follicles and dermal adipose tissue (Ramos R, Plikus MV) -- Chapter 7. Lymphatic vasculature and hair follicle regeneration (Cazorla A, Perez-Moreno M) -- Chapter 8. In vitro and ex vivo hair follicle models to explore therapeutic options for hair regeneration (Bertolini M, Piccini I, McElwee KJ) -- Chapter 9. Extracellular vesicles including exosomes for hair follicle regeneration (Aberdam E, le Riche A, Bordes S, Closs B, Park BS, Aberdam D) -- Chapter 10. Stem cell-based therapies for hair loss: what is the evidence from a clinical perspective? (Park BS, Choi HI) -- Chapter 11. Induced pluripotent stem cell approach for hair follicle regeneration (Pinto A, Terskikh AV) -- Chapter 12. Biofabrication technologies in hair neoformation (Abreu CM, Gasperini L, Marques AP) -- Chapter 13. Wound healing induced hair follicle regeneration (Jiang Y, Myung P) -- Chapter 14. Hair follicles in wound healing and skin remodeling (Plotczyk M, Jimenez F) .
    Abstract: This book aims to comprehensively review the current cell-based strategies under investigation to achieve the regeneration of human hair follicles. The unique capacity of the human hair follicle to self-renew explains why this complex “mini-organ” has always attracted so much interest as a model for researchers to study stem cell biology and regenerative medicine. The hair follicle is considered a main reservoir of cutaneous stem cells, containing several pools of epithelial, melanocyte, and mesenchymal stem cells involved in hair follicle self-regeneration and pigmentation. In addition, while some of the different follicular cell types contribute to hair shaft growth, others participate in very important interfollicular functions such as dermal remodeling, re-epithelialization after wounding, and cutaneous stem cell homeostasis. The idea of human hair follicle regeneration either “de novo” or by activating dormant miniaturized follicles is not new, yet still continues to arouse enormous interest in the pursuit of a definitive cure for baldness. In contrast to hair follicle regeneration in mice, the attempts made with human follicles have been disappointing in terms of efficiency. However, recent advances in stem cell biology—as well as the appearance of new technologies like 3D printing—have revived expectations in this field of research. This book is divided into four sections. The first part includes an overview of the strategies used in hair follicle regeneration and a historical summary of the most important achievements to date. Parts two and three comprise the main body of the book, with detailed descriptions of the cells and tissue structures involved in hair follicle regeneration, followed by an elaboration of the different therapeutic strategies, engineering techniques, and a clinician’s perspective of stem cell-based therapies in hair loss treatments. Finally, the fourth part reviews the important contribution of the hair follicle in healing cutaneous wounds through the regeneration and remodeling of the dermis and epidermis after injury, as well as wound induced hair follicle neogenesis that occurs when the skin is injured.
    Type of Medium: Online Resource
    Pages: XII, 307 p. 73 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030983314
    Series Statement: Stem Cell Biology and Regenerative Medicine, 72
    DDC: 610.72
    Language: English
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  • 76
    Keywords: Microbiology. ; Botany. ; Biotechnology. ; Physical geography. ; Microbial ecology. ; Forestry. ; Microbiology. ; Plant Science. ; Biotechnology. ; Earth System Sciences. ; Microbial Ecology. ; Forestry.
    Description / Table of Contents: Part I. Fungal Symbiosis -- Current Status–Enlightens in Its Biology and Omics Approach on Arbuscular Mycorrhizal Community -- An Insight through Root-Endophytic-Mutualistic Association in Improving Crop Productivity and Sustainability -- Interaction Between Root Endophytes and Plants: Their Bioactive Products and Significant Functions -- Unravelling the Role of Endophytes in Micronutrient Uptake and Enhanced Crop Productivity -- Dual and Tripartite Symbiosis of Invasive Woody Plants -- Eco-friendly Association of Plants and Actinomycetes -- The Arbuscular Mycorrhizal Symbiosis of Trees: Structure, Function, and Regulating Factors -- Effectiveness of Arbuscular Mycorrhizas in Improving Carob Culture in the Mediterranean Regions -- Leaf Endophytes and Their Bioactive Compounds -- Role of Endophytic Fungus Piriformospora indica in Nutrient Acquisition and Plant Health -- The Role of Symbiotic Fungi in Nutri-Farms -- Part II. Bacterial Symbiosis -- Understanding the Evolution of Plant Growth-Promoting Rhizobacteria -- Rhizobia–Legume Symbiosis During Environmental Stress -- Archaeal Symbiosis for Plant Health and Soil Fertility -- Microbial Symbionts of Aquatic Plants -- Rhizobium Presence and Functions in Microbiomes of Non-leguminous Plants -- Part III. Insect–Fungus Mutualism -- Symbiotic Harmony Between Insects and Fungi: A Mutualistic Approach -- Panorama of Metarhizium: Host Interaction and Its Uses in Biocontrol and Plant Growth Promotion -- Arbuscular Mycorrhizal Fungi: Potential Plant Protective Agent Against Herbivorous Insect and Its Importance in Sustainable Agriculture -- Eradication of Malaria by the Mutualistic Interaction Between Wickerhamomyces anomalus and Anopheles sp -- Part IV. Microbial Symbiosis in Disease and Stress Management -- Halophyte–Endophyte Interactions: Linking Microbiome Community Distribution and Functionality to Salinity -- Root Endophytic Microbes and Their Potential Applications in Crop Disease Management -- Do Mycorrhizal Fungi Enable Plants to Cope with Abiotic Stresses by Overcoming the Detrimental Effects of Salinity and Improving Drought Tolerance? -- Combined Use of Beneficial Bacteria and Arbuscular Mycorrhizal Fungi for the Biocontrol of Plant Cryptogamic Diseases: Evidence, Methodology, and Limits -- Remediation of Toxic Metal-Contaminated Soil and Its Revitalisation with Arbuscular Mycorrhizal Fungi.
    Abstract: This book explores microbial symbiosis, with a particular focus on soil microorganisms, highlighting their application in enhancing plant growth and yield. It addresses various types of bacterial and fungal microbes associated with symbiotic phenomena, including rhizobium symbiosis, arbuscular mycorrhizal symbiosis, ectomycorrhizal symbiosis, algal/lichen symbiosis, and Archeal symbiosis. Presenting strategies for employing a diverse range of bacterial and fungal symbioses in nutrient fortification, adaptation of plants in contaminated soils, and mitigating pathogenesis, it investigates ways of integrating diverse approaches to increase crop production under the current conventional agroecosystem. Providing insights into microbial symbioses and the challenges of adopting a plant-microbe synergistic approach towards plant health, this book is a valuable resource for researchers, graduate students and anyone in industry working on bio-fertilizers and their agricultural applications. .
    Type of Medium: Online Resource
    Pages: VII, 489 p. 49 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030519162
    Series Statement: Soil Biology, 60
    DDC: 579
    Language: English
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  • 77
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Regenerative medicine. ; Reproductive health. ; Stem cells. ; Cancer. ; Biomedical engineering. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Reproductive Medicine. ; Stem Cell Biology. ; Cancer Biology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Basic Concepts of Stem Cells: The Facts and Hype in Stem Cells Research and Development -- Chapter 2. Embryonic and Pluripotent Stem Cells -- Chapter 3. Adult Stem Cells: Hematopoietic Stem Cells, and Control Of Hematopoiesis -- Chapter 4. Adult Stem Cells: Adult Stem Cells: Mesenchymal Stromal Cells, Endothelial Progenitor Cells and Pericytes -- Chapter 5. Cancer Stem Cells and the Development of Cancer -- Chapter 6. Stem Cell Applications In Metabolic Disorders: Diabetes Mellitus -- Chapter 7. Epigenetics in Stem Cell Biology -- Chapter 8. Practicum: Isolation of Bone Marrow and Adipose Tissue Mesenchyme Stromal Cells -- Chapter 9. Induced Pluripotent Stem Cells: Biology, History and in-vitro Generation -- Chapter 10. Tissue Engineering Modalities and Nanotechnology -- Chapter 11. Practicum: Scaffold engineering using the amniotic membrane -- Chapter 12. The Scientific Method, Ethical Consideration and Implications in Stem Cell Research.
    Abstract: This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.
    Type of Medium: Online Resource
    Pages: X, 374 p. 45 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030553593
    Series Statement: Learning Materials in Biosciences,
    DDC: 660.6
    Language: English
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  • 78
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunospecificity. ; Biotechnology. ; Proteins . ; Adaptive Immunity. ; Chemical Bioengineering. ; Protein Biochemistry.
    Description / Table of Contents: Chapter 1. Introduction by the editors -- Chapter 2. Antibodies – A History of their Discovery and Properties -- Chapter 3. Monoclonal Antibodies and Hybridomas -- Chapter 4. Antibody Display Systems -- Chapter 5. Transgenic Animals for the Generation of Human Antibodies -- Chapter 6. Applications of Antibodies in Therapy, Diagnosis & Science -- Chapter 7. Bispecific antibodies -- Chapter 8. Antibody-Drug Conjugates -- Chapter 9. Alternative Binding Scaffolds – multipurpose binders for applications in basic research and therapy -- Chapter 10: Chimeric antigen receptor (CAR) redirected T cells -- Chapter 11. Improvement of Key Characteristics of Antibodies -- Chapter 12. Engineering therapeutic antibodies for development -- Chapter 13. Eukaryotic expression systems for upstream pro-cessing of monoclonal antibodies -- Chapter 14. Antibody Validation.
    Abstract: This highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an overview of the latest methods in antibody identification, improvement and biochemical engineering. Furthermore, alternative antibody formats and bispecific antibodies are discussed. The book’s content is based on lectures for the specializations “Protein Engineering” and “Medical Biotechnology” within the Master’s curriculum in “Biotechnology.” The lectures have been held at the University of Natural Resources and Life Sciences, Vienna, in cooperation with the Medical University of Vienna, since 2012 and are continuously adapted to reflect the latest developments in the field. The book addresses Master’s and PhD students in biotechnology, molecular biology and immunology, and all those who are interested in antibody engineering.
    Type of Medium: Online Resource
    Pages: VIII, 388 p. 69 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030546304
    Series Statement: Learning Materials in Biosciences,
    DDC: 571.9646
    Language: English
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  • 79
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Immunology. ; Biomedical Research. ; Biotechnology.
    Description / Table of Contents: Western blotting: How it began -- 2. Basics of Western Blotting -- 3.Basic Calculations in Western Blotting -- 4.Choosing The Right Antibody For Western Blotting -- 5. Sample Preparation -- 6. Blocking membranes at places that do not have transferred proteins -- 7. A Basic Method for Western Blotting -- 8. Trouble Shooting Western Blotting -- 9. Using Biotin to demonstrate western and dot blotting in University Practical Classes- A Guide To Instructors -- 10. Nitrocellulose Membrane Art -- 11. The Use Of A Harmless Invisible Ink To Send Secret Messages On Nitrocellulose Membranes And As A Substitute For The Harmful Radioactive Ink Used As A Marker In ECL Membrane Assays -- 12. Fingerprinting On Nitrocellulose And Polyvinylidene Difluoride Membrane -- 13. Spectrometric Determination Of Protein For Electrophoresis -- 14. Concentrating Proteins For Western Blotting -- 15. Dissolving Proteins Using Lysis Buffer -- 16. Blotting And Detecting Glycosaminoglycans -- 17. Passive Blotting From Tissue Slices -- 18. Localizing Proteins by Tissue Printing -- 19. Ultrasound Blotting -- 20. Obtaining Several Blots From A Single SDS-PAGE Gel By Passive Transfer -- 21. Diffusion Blotting From SDS-PAGE Gels Supported By Solid Plastic -- 22. Dot-Immunobinding -- 23. Simultaneous Immunoblotting Analysis With Activity Gel Electrophoresis -- 24. Protein Blotting By Centrifugation -- 25. Blotting And Immunostaining Of Multiple Antigenic Peptides -- 26. High Molecular Weight Protein Blotting Using Agarose Gel Electrophoresis -- 27. Cetyltrimethylammonium bromide PAGE And Eastern Blotting -- 28. Purification Of Autoantibodies Bound To An Autoantigen Immobilized On A Membrane Strip -- 29. Miniaturized Blotting -- 30. Affinity Immunoblotting -- 31. Transferring Coomassie Blue Stained Proteins from Polyacrylamide Gels To Transparencies -- 32. Protein Transfer From Immobilized pH Gradient Gels -- 33. SDS PAGE To Immunoblotting In Sixty Minutes -- 34. Western Blot Analysis Of Protein-DNA Complexes Formed DuringGel Shift Experiments -- 35. Electrophoretic Transfer Of High And Low Molecular Weight Proteins To Membranes Using Heat -- 36. Grid-immunoblotting -- 37. Far-western Blotting -- 38. Native Electrophoresis And Western Blot Analysis -- 39. Efficient Electroblotting Of Low Molecular Weight Protein After Staining With Coomassie -- 40. Avoiding Non-specific Binding Of Secondary Antibodies In Immunoblotting By Double-blotting -- 41.A Brief Introduction To Other Protein Blotting Methods -- 42. Quantitative Computerized Western Blotting In Detail -- 43. Common Problems In Electrophoresis.
    Abstract: This book fills the need for a simplified text covering western blotting protocols aimed not just at high school and college students, but the researcher with little to no experience in these techniques. It provides the principles, basic methodology, and tips and tricks to avoiding the common pitfalls of western blotting. The book also introduces simple protocols that can transform western blotting into a fun method, such as sending secret messages on membranes or using nitrocellulose membrane as a canvas for art. In addition to the techniques, this book also covers the history of western blotting, which originated from the development of the blotting of DNA. It then delves into the importance of protein blotting, brought to the fore by the fact that the procedure has been evolving constantly since its inception in 1979, and the fact that the scientific community is faced with a multitude of ways and means of transferring proteins to membranes.
    Type of Medium: Online Resource
    Pages: XXIII, 467 p. 611 illus., 170 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030706845
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 571.96
    Language: English
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  • 80
    Keywords: Plant biotechnology. ; Biotechnology. ; Nanotechnology. ; Regenerative medicine. ; Plant Biotechnology. ; Biotechnology. ; Nanotechnology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Preface -- Nanomedicine: General Introduction from A to Z -- Immunology and Nanotechnology: Effects and Affects -- Role of Nanotechnology in Sensor Development -- Nanotechnology in the Characterization of Cancer -- Nano Vaccine -- Nanotechnology in Theranostics and In Vivo Imaging -- The Implication of Physical and Chemical Characterization of Therapeutic and Imaging Applications -- Polymers in Nanomedicine -- Delivery of Drug Payloads to Organs and Organ-Systems of Human Beings -- Drug Delivery Towards Cancer -- Drug Delivery Towards Malaria -- Nanotechnology in Tissue Engineering and Implant Development -- Interactions Between Nano-Delivery Agents and Immune Systems -- The Fate of Drug Delivery Agents after Delivery of Payload -- Index.
    Abstract: Nanomedicine is the field of science that deals with organic applications of medicine at the nanoscale level. It primarily addresses finding, anticipating, and treating sickness, as well as using nanotechnology to assist in controlling human frameworks at the cellular level. The nature of nanotechnology allows it to address numerous medical issues in humans. This book offers comprehensive information to better comprehend and apply multifunctional nanoparticles in nanomedicine, and thus open avenues in the field. Medicating at the nanolevel is an exceptional therapeutic avenue, as it avoids symptoms associated with conventional medicines. This book investigates recent insights into structuring novel drug delivery frameworks. It concentrates on the physical characteristics of drug delivery transporters, and the preliminary procedures involved in their use. The book offers in-depth detail that benefits academics and researchers alike, containing broad research from experts in the field, and serves as a guide for students and researchers in the field of nanomedicine, drug delivery, and nanotechnology.
    Type of Medium: Online Resource
    Pages: XIII, 265 p. 38 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030610210
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 631.52
    Language: English
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  • 81
    Keywords: Microbial ecology. ; Agriculture. ; Botany. ; Microbiology. ; Biotechnology. ; Environment. ; Microbial Ecology. ; Agriculture. ; Plant Science. ; Microbiology. ; Biotechnology. ; Environmental Sciences.
    Description / Table of Contents: Part I: Nitrogen physiology and ecology -- Chapter 1: Physiology and distribution of Nitrogen in soils -- Chapter 2: Ecophysiology of nitrogen in symbiotic relationships of plants and microorganisms -- Chapter 3: Ecological perspectives on soil microbial community involved in N-cycling -- Chapter 4: Pedological assessment of soil organic carbon and total nitrogen contents in wetland rice ecosystems of Majuli river island, Assam, India -- Part II: Nitrogen cycle and pathway -- Chapter 5: Functional Nitrogen in Rhizosphere -- Chapter 6: Potential contribution of soil microflora and fauna in Nitrogen cycle: A comprehensive study -- Chapter 7: Unraveling microbial nitrogen pathway in rhizosphere -- Chapter 8: Role of root exudates on different processes of nitrogen cycle in rhizosphere -- Part III: Techniques and applications -- Chapter 9: Techniques for improving nitrogen use efficiency in rice -- Chapter 10: Tools for characterization of nitrogen fixing microbes -- Chapter 11: Biopriming is emerging as a supplemental strategy for improving nitrogen use efficiency of crop species -- Chapter 12: Overview of the role of nitrogen in copper pollution and bioremediation mediated by plant-microbe interactions -- Part IV: Metagenomics -- Chapter 13: Metagenomics for improving soil fertility -- Chapter 14: Soil microbial diversity and metagenomics -- Part V: Bacteria in nitrogen fixation -- Chapter 15: Beneficial effects of Nitrogen fixing bacteria for agriculture of the future -- Chapter 16: Functional Diversity of Nitrogen-Fixing Plant Growth Promoting Rhizobacteria-The Story so Far -- Chapter 17: Bacterial mutants for enhanced nitrogen fixation -- Chapter 18: Perspectives of nitrogen fixing Bacillus spp -- Chapter 19: Quorum Sensing Enhances Nitrogen Uptake In Plants -- Part VI: Fungi in nitrogen fixation -- Chapter 20: Fungi and nitrogen cycle: symbiotic relationship, mechanism and significance -- Chapter 21: Arbuscular Mycorrhizae in Sustainable Plant Nitrogen Nutrition: Mechanisms and Impact -- Chapter 22: Nitrogen fixing fungi for development of biofertilizer and future strategies -- Chapter 23: Iron toxicity and its relation to nitrogen and phosphorus availability in ectomycorrhizal fungi -- Part VII: Algae in nitrogen fixation -- Chapter 24: Role of Algae in soil nitrogen fixation -- Chapter 25: Role of cyanobacteria in rhizospheric nitrogen fixation -- Chapter 26: Molecular aspects and oxygen relations of nitrogen fixation in cyanobacteria.
    Abstract: This book highlights the latest discoveries about the nitrogen cycle in the soil. It introduces the concept of nitrogen fixation and covers important aspects of nitrogen in soil and ecology such as its distribution and occurrence, soil microflora and fauna and their role in N-fixation. The importance of plant growth-promoting microbes for a sustainable agriculture, e.g. arbuscular mycorrhizae in N-fixation, is discussed as well as perspectives of metagenomics, microbe-plant signal transduction in N-ecology and related aspects. This book enables the reader to bridge the main gaps in knowledge and carefully presents perspectives on the ecology of biotransformations of nitrogen in soil.
    Type of Medium: Online Resource
    Pages: IX, 568 p. 67 illus., 53 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030712068
    Series Statement: Soil Biology, 62
    DDC: 579.17
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Regenerative medicine. ; Biotechnology. ; Biomaterials. ; Biomedical engineering. ; Regenerative Medicine and Tissue Engineering. ; Biotechnology. ; Biomaterials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: 1. Introduction (market, clinical need, bone grafts) a. Choice 1: Alan S Herford, DDS, MD (Loma Linda University) -- 2. Basic bone biology a. Choice 1: David T Scadden, MD (Massachusetts General Hospital) -- 3. Principles of bone tissue engineering a. Choice 1: Antonios G Mikos, PhD (Rice University) b. Choice 2: Susmita Bose, PhD (Washington State University) -- 4. Additive manufacturing technologies a. Choice 1: Anthony Atala, MD (Wake Forest School of Medicine) b. Choice 2: Jennifer A Lewis, ScD (Harvard University) -- 5. 3D printing scaffolds for oral and maxillofacial regeneration a. Choice 1: Fernando PS Guastaldi, PhD (Massachusetts General Hospital) and Maria J Troulis, MsC (Massachusetts General Hospital) -- 6. 3D printing scaffolds for orthopedic joint tissue engineering a. Choice 1: Anthony J Melchiorri, PhD (Rice University) -- 7. 3D bioprinting and nanotechnology for bone tissue engineering a. Choice 1: Bhushan Mahadik, PhD (University of Maryland) -- 8. Bioreactors and scale-up in bone tissue engineering a. Choice 1: John P Fisher, PhD (University of Maryland) -- 9. Commercialization, legal, and regulatory considerations to translate 3D printing-based products to the marketplace and the clinic a. Choice 1: Anthony Ratcliffe, PhD (Synthasome, Inc.) -- 10. Future directions and challenges a. Choice 1: James J Yoo, PhD (Wake Forest School of Medicine) b. Choice 2: Fernando PS Guastaldi, PhD (Massachusetts General Hospital) and Bhushan Mahadik, PhD (University of Maryland).
    Abstract: This book provides a comprehensive overview of the state-of-the-art research as well as current challenges and strategies to reconstruct large bone defects employing 3D printing technology. Various topics covered include different 3D printing technologies that can be applied for bioengineering bone, the aspects of basic bone biology critical for clinical translation, tissue engineering platforms to investigate the bone niche microenvironment, the pathway to clinical translation, and regulatory hurdles. Bone Tissue Engineering: State-of-the-Art in 3D Printing is an ideal book for students and researchers interested in learning more about the latest advances in employing different 3D printing technologies for bone tissue engineering. .
    Type of Medium: Online Resource
    Pages: XIII, 317 p. 81 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030920142
    DDC: 612.028
    Language: English
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  • 83
    Keywords: Regenerative medicine. ; Biomedical engineering. ; Biotechnology. ; Mechanical engineering. ; Mathematics Data processing. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Biotechnology. ; Mechanical Engineering. ; Computational Science and Engineering.
    Description / Table of Contents: Part I: Biological Characterization of Bone Tissue -- Chapter 1. Bone: functions, structure and physiology -- Chapter 2. Bone Quality Assessment at the Atomic Scale -- Part II: Bone Remodelling algorithms -- Chapter 3. Meshless, Bone Remodelling and Bone Regeneration Modelling -- Chapter 4. Dynamic biochemical and cellular models of bone physiology: integrating remodeling processes, tumor growth and therapy -- Chapter 5. Mathematical Modelling of Spatio-Temporal cell dynamics observed during Bone Remodelling -- Chapter 6. A Mechanostatistical Approach to Multiscale Computational Bone Remodelling -- Part III: Numerical simulation of bone tissue and adjacent structures -- Chapter 7. Finite Element Analysis of Bone and Experimental Validation -- Chapter 8. Computational modelling of tissue engineered cartilage constructs -- Chapter 9. On the Computational Biomechanics of the Intervertebral Disc -- Index.
    Abstract: This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.
    Type of Medium: Online Resource
    Pages: XIV, 241 p. 68 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030375416
    Series Statement: Lecture Notes in Computational Vision and Biomechanics, 35
    DDC: 612.028
    Language: English
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  • 84
    Keywords: Immunospecificity. ; Biology Technique. ; Immunology. ; Biotechnology. ; Adaptive Immunity. ; Biological Techniques. ; Immunology. ; Biotechnology.
    Description / Table of Contents: History of IgY-Technology -- Characteristics of IgY antibody -- Chicken keeping -- Basics of egg laying processes -- IgY extraction from yolk -- Immunization of chickens -- Cost calculation of industrial production of IgY preparations -- Application of IgY.– Human Medicine -- Application of IgY.– Veterinary Medicine -- Use of IgY Ab in aquaculture -- Molecularbiological methods for IgY-Ab production -- IgY receptors -- Additional aspects of IgY-technology.
    Abstract: This first edited Volume on IgY-Technology, addresses the historical and dynamic development of IgY-applications. The authors cover the biological basis and theoretical context, methodological guidance, and applications of IgY-Technology. A focus is laid on the use of IgY-antibodies for prophylactic/therapeutic purposes in human and veterinary medicine. Aside from applications, the chapters also offer an evolutionary understanding of the IgY molecule, IgY receptors and practical prerequisites to produce IgY-antibodies. Guidance is given for every step of the process. Starting with an introduction to hens as a model species and including hen husbandry, hen egg-laying capacity and total IgY outcomes. Readers will also learn about immunization techniques, the advantages and limitations of different IgY extraction methods, as well as storage stability of the final product. The last part of the volume highlights hands-on aspects of applications, such as IgY delivery strategies, new methods to produce monoclonal IgY-antibodies or production of functional IgY fragments by phage-display as well as commercial exploitation of the technology. Thus, this book is a valuable resource and guide for Scientists, Clinicians and Health Product Developers in both human and veterinary medicine.
    Type of Medium: Online Resource
    Pages: XV, 313 p. 48 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030726881
    DDC: 571.9646
    Language: English
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  • 85
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Designing Commonbean (Phaseolus Vulgaris L.)For Abiotic Stress Tolerance -- A Scintillating Journey Of Genomics In Simplifying Complex Traits And Development Of Abiotic Stress Resilient Chickpeas -- Genomic Designing for Abiotic Stress Tolerance in Pea (Pisum sativum L.) -- Advanced Breeding Strategies For Abiotic Stress Tolerance In Cowpea -- Breeding For Abiotic Stress Tolerance In Lentil In Genomic Era -- Genomic Design For Abiotic Stress Resistance In Pigeonpea -- Genetic and Genomic Research for Abiotic stresses in faba bean -- Genomic Designing For Abiotic Stress Tolerance In Mungbean And Urdbean -- Genomic Designing Towards Development of Abiotic Stress Tolerant Grass Pea for Food and Nutritional Security.
    Abstract: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in pulse crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a pulse crop in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Type of Medium: Online Resource
    Pages: XXV, 381 p. 31 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030910396
    DDC: 580
    Language: English
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  • 86
    Keywords: Biotechnology. ; Neurosciences. ; Biomaterials. ; Biotechnology. ; Neuroscience. ; Biomaterials.
    Description / Table of Contents: General aspects of neural diseases and requirements of CNS implantable biomaterials as diagnostic and/or therapeutic tools -- Characteristics of the traumatic brain and spinal cord injured patients as a host of a CNS implanted biomaterial -- Electrophysiological recording at the damaged neural tissue -- Mechanical aspects of biomaterials and neural tissues -- Nanostructures to potentiate axon navigation and regrowth in CNS damaged tissue.-Electrical stimulation-based approaches focused on electrodes -- Engineered 2D and 3D biomaterials for neural applications -- Magnetic nanoparticles for the treatment of neural pathologies -- Magnetic devices for sensing at the neural tissue -- Cell therapies for neural applications -- Basics on electrical modeling of the electrode/tissue interface -- CNS therapeutic approaches in implantable devices for neurological diseases -- Index.
    Abstract: This book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to cure them. The interdisciplinary nature of this book makes it a perfect candidate for the interest of a broad audience, from clinicians working on neural diseases to scientists whose work focuses on the nervous tissue (neuroscientists) and/or materials science. Undergraduate and PhD students can also benefit from the knowledge and discussion included in this book.
    Type of Medium: Online Resource
    Pages: XXVI, 310 p. 77 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030814007
    DDC: 660.6
    Language: English
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  • 87
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. History, Botanical and Taxonomic Description, Domestication and Spread -- Chapter 2. Economic, Nutritional and Health Importance -- Chapter 3. Genetic and Genomic Resources for Crop Improvement in Finger Millet -- Chapter 4. Paradigm Shift from Genetics to Genomics: Characterization of Diversity and Prospects of Molecular Markers -- Chapter 5. Molecular Mapping in Finger Millet -- Chapter 6. The Complete Genome Sequence of Finger Millet -- Chapter 7. Comparative Genomics in Finger Millet -- Chapter 8. Finger Millet Transcriptome Analysis Using High Throughput Sequencing Technologies -- Chapter 9. Seed Biology and Packaging of Finger Millet Using Omics Approaches for Nutritional Security -- Chapter 10. A Nutritional Crop Factory of Quality Seed Storage Proteins for Combating Malnutrition -- Chapter 11. Finger Millet Genome Analysis and Nutrient Transport -- Chapter 12. Finger Millet as Input Use Efficient and Organic By Default Crop -- Chapter 13. Molecular Basis of Biotic and Abiotic Stress Tolerance in Finger Millet -- Chapter 14. Genetic Transformation for Crop Improvement and Biofortification -- Chapter 15. Novel Prospective On Suppression of Ageing By The Consumption of Finger Millet -- Chapter 16. Finger Millet Holistic Value Chain Approach.
    Abstract: This book is the first comprehensive compilation of deliberations on domestication, genetic and genomic resources, breeding, genetic diversity, molecular maps & mapping of important biotic stress as well as nutritional quality traits, genome sequencing, comparative genomics, functional genomics and genetic transformation. The economic, nutritional and health benefits especially antioxidants mediated antiaging effects of finger millet are also discussed. It also presents the input use efficiency, wide adaptation, post-harvest processing and value addition of the crop. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers and scientists in the academia and relevant private companies interested in genetics, pathology, molecular genetics and breeding, genetic engineering, structural and functional genomics and nutritional quality aspects of the crop. This book is also useful to seed and pharmaceutical industries.
    Type of Medium: Online Resource
    Pages: XII, 296 p. 68 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031008689
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 88
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Biophysics. ; Biomathematics. ; Biotechnology. ; Biomedical engineering. ; Bioinformatics. ; Computational and Systems Biology. ; Biophysics. ; Mathematical and Computational Biology. ; Biotechnology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: 1-Digging for Significant Genes in Microarray Expression Data Based on Systematic Sampling and Hierarchal Clustering Algorithm -- 2-A DSS for predicting Lymphoma in primary Sjogren’s Syndrome patients -- 3-Decision Support System for Breast Cancer Detection Using Biomarker Indicators -- 4-Hepatocellular Carcinoma Detection Using Machine Learning Techniques -- 5-Web-based Decision Support System for Coronary Heart Disease Diagnosis -- 6-A Decision Support System for the Prediction of Drug Predisposition through Personality Traits -- 7-Development of a diagnostic tool for balance disorders based on machine learning techniques -- 8-Systems Approaches in the Common Metabolomics in Acute Lymphoblastic Leukemia and Rhabdomyosarcoma Cells: A Computational Approach -- 9-Bioinformatics Analyses of Spatial Peripheral Circadian Clock-Mediated Gene Expression of lucocorticoid Receptor-related Genes -- 10-Machine Learning for Autistic Spectrum Disorder Risk Screening -- 11-Mobile Application for Monitoring and Preventing Cognitive Decline through Lifestyle Intervention -- 12-Virtual Reality Zoo Therapy for Alzheimer’s Disease Using Real-time Gesture Recognition -- 13-Validation of the Greek Version of Social Media Disorder Scale -- 14-Adiponectin and its Effects on Acute Leukemia Cells: An Experimental and Bioinformatics Approach -- 15-Nature and quantum inspired procedures - a short literature review -- 16-Handling the cellular complex systems in Alzheimer’s disease through a graph mining approach -- 17-Debunking the neuromyth of learning style -- 18-Expert characteristics: implications for expert systems -- 19-Improving the Run-Time of Space E cient n-gram Data Structures using Apache Spark -- 20-Development of a protein biochip platform for Parkinson’s disease -- 21-The Cultural adaptation of the iSupportDementia in Greece -- 22-The use of data collection and big data analysis in Neurodegenerative disease prevention -- 23-Fractal Dynamics in the RR Interval of Craniopharyngioma and Adrenal Tumor in Adolescence -- 24-Bioinformatics approaches for Parkinson’s disease in clinical practice: Data- driven biomarkers and pharmacological treatment -- 25-Emerging Machine Learning techniques for modelling cellular complex systems in Alzheimer’s disease -- 26-Cognitive Enhancement Through Mathematical Problem Solving -- 27-Cognitive tasks of an information system for memory training and cognitive enhancement using mobile devices -- 28-An application for exploring visual perception. A pilot neuroeducational study -- 29-Genes Classification Based on Multi Class SVMs with Systematic Sampling and Hierarchical Clustering (SSHC) Algorithm -- 30-Multinetwork motor learning as a model for dance in neurorehabilitation -- 31-Controlling the chimera form in the Leaky Integrate-and-Fire model -- 32-Qualitative differences between the Semi-separable and the “Almansi type” Stokes stream function expansions in the study of biological fluids -- 33-A multiscale mathematical model for tumor growth, incorporating the GLUT1 expression.
    Abstract: The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. Computational methodologies for implementation on the discovery of biomarkers for neurodegenerative diseases are extensively discussed. This volume focuses on the sessions from the conference regarding computational biology and bioinformatics.
    Type of Medium: Online Resource
    Pages: XV, 288 p. 105 illus., 92 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030787752
    Series Statement: Advances in Experimental Medicine and Biology, 1338
    DDC: 570.285
    Language: English
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  • 89
    Keywords: Bioethics. ; Biology. ; Biotechnology. ; Welfare economics. ; Bioethics. ; Biological Sciences. ; Biotechnology. ; Social Economy.
    Description / Table of Contents: PART I. Introduction and Overview -- Introduction: Bioeconomy and Sustainability -- PART II. Energy and Land Use -- “Global Shifting Agriculture” and Bioeconomy: Challenges for the Sustainable Use of Global Land Resources -- Sustainable Resources: From Plants to Products -- PART III. Nutrition and Food Ethics -- Food as a Moral Problem -- Bioeconomy and Food Security -- Acceptance of Insects and In Vitro Meat as a Sustainable Meat Substitute in Germany: In Search of the Decisive Nutritional-Psychological Factors -- PART IV. Technology and Governance -- Characteristics of Innovation in Bioeconomy -- Spatial Implications of the Leitmotif Shift from Biotechnology to Bioeconomy -- Problem Structures of Bioenergy Policy in the Power and Heat Sector in Germany -- The Bioeconomy Transformation in the German Rheinische Revier: Stakeholders and Discourses in Media Coverage -- PART V. Regulation and Economics -- Bioeconomy and Genome Editing: A Comparison Between Germany and the Netherlands -- Monitoring and Measuring Bioeconomy -- Resource Sufficiency in a Sustainable Bioeconomy: A Predator-Prey Perspective -- Agriculture in the Bioeconomy: Economics and Policies -- PART VI. Normativity and Ethics -- Bioeconomy and Ethics -- Bioeconomy from the Perspective of Environmental Ethics -- Conditions for an Ethically Responsible and Sustainable Bioeconomy Based on Hans Jonas’ Ethics of Responsibility -- Bioeconomy as a Normative Concept of Resilience: Challenges and Opportunities -- PART VII. Conclusions and Outlook -- Bioeconomy: Challenges and Conflicts from an Interdisciplinary Perspective -- Bioeconomy Beneath and Beyond: Persisting Challenges from a Philosophical and Ethical Perspective.
    Abstract: In this edited volume, scientists from different disciplines discuss modern biotechnological processes and a knowledge-based bioeconomy. The authors base their arguments on ecological, economic, legal, social and ethical aspects. Moreover, they explore the opportunities, risks, and challenges of bioeconomic concepts and biotechnologies in many subject areas. The chapters consider land use, nature and environment, nutrition, technology and governance, energy, economy, law and regulation, as well as ethics. A special focus should be on new technologies and how they can be used, without compromising the ambitious goal of creating a more sustainable, but also fair world. To do justice to this broad array of topics, the editors frame all topics in overarching introductions and close the volume with final conclusions. Thereby this volume offers data and critical thoughts for any member of a Bioeconomy – be it from academia, the industry or public regulation.
    Type of Medium: Online Resource
    Pages: VI, 380 p. 21 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874025
    DDC: 174.2
    Language: English
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  • 90
    Keywords: Virology. ; Biomedical engineering. ; Biotechnology. ; Microbial genetics. ; Analytical biochemistry. ; Therapeutics. ; Virology. ; Biomedical Engineering and Bioengineering. ; Biotechnology. ; Microbial Genetics. ; Analytical Biochemistry. ; Therapeutics.
    Description / Table of Contents: Chapter 1: Bioprocessing and analytical development for virus-based therapeutics -- Chapter 2: Viral Vector Upstream Processing and Clarification -- Chapter 3: Upstream processing of viral therapeutics: From host cell expansion to virus production -- Chapter 4: Leveraging virus biology and host genetic conflicts for cell line development and engineering for virus-based therapeutics -- Chapter 5: Overview of Current Downstream Processing for Modern Viral Vectors -- Chapter 6: Filtration Principles and Techniques for Bioprocessing of Viral Vector–Based Therapeutics -- Chapter 7: Chromatographic purification of viruses: State of the art and current trends -- Chapter 8: Purifying Viral Vectors - A Review of Chromatography Solutions -- Chapter 9: Particle analytics - Comparative approaches for analysis of viral vectors -- Chapter 10: Phase-Appropriate Potency Assay Development for AAV-based Gene Therapy Products -- Chapter 11: Quantification of virus infectivity – the key assay for the development of viral therapeutics -- Chapter 12: Product-related impurities in therapeutic virus bioprocessing -- Chapter 13: Process Analytical Technologies (PAT) and Quality by Design (QbD) for bioprocessing of virus-based therapeutics -- Chapter 14: Methods and practical considerations in imaging viral therapeutics -- Chapter 15: Application of NMR Spectroscopy in Viral Assembly Characterization -- Chapter 16: Improved Production Strategies for Oncolytic Measles Viruses as a Therapeutic Cancer Treatment -- Chapter 17: Recent Advancements and Challenges in Recombinant Expression for Commercial Production of Virus Like Particles (VLPs) -- Chapter 18: Oncolytic viruses and viral gene therapy vectors: Principles of safety.
    Abstract: This book reviews the knowledge, methods and available techniques in the rapidly advancing field of virus based vaccines and gene therapeutics. It also highlights new innovative tools and interdisciplinary techniques for bioprocess development and analytics of viruses and viral vectors. As such, it provides a timely and highly relevant resource, since current advances in pharmaceutical research have seen the rise of vaccines and advanced therapeutics and medicinal products (ATMPs), that rely on the power of viruses. However, developing bioprocesses and analytics required to create this often called “magic bullet” (i.e. gene therapy) remains an extremely challenging and costly task. This book offers strategies for overcoming hurdles and difficulties within in all the necessary steps of viral vector development - from scalability to purification methods and quality control. The book is intended for researchers working in academia or industry, as well as graduate students pursuing a career in virology.
    Type of Medium: Online Resource
    Pages: XVI, 442 p. 84 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031284892
    DDC: 579.2
    Language: English
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  • 91
    Keywords: Biotechnology. ; Radiology. ; Biomedical engineering. ; Biotechnology. ; Radiology. ; Biomedical Engineering and Bioengineering. ; Radiology.
    Description / Table of Contents: 1. The Nature and Scope of Research -- 2. Quantitative and Qualitative Approaches to Research-An Overview of Approaches -- 3. Planning Your Research -- 4. The Literature Review -- 5. Quantitative Research Methods -- 6. Qualitative Research Methods -- 7. Data Collection, Analysis and Interpretation -- 8. Communicating Research Findings -- 9. Research Examples in Medical Imaging-A Selected Review.
    Abstract: This book addresses essential principles of research according to the scientific method for medical imaging technology research. The scope of this book covers the nature of scientific research; quantitative and qualitative approaches essentials; research planning; literature review fundamentals; research methods; data collection, analysis, and interpretation; and communicating research findings. The book meets the educational requirements on Research Principles and Concepts (for entry to practice) of the following professional radiologic technology associations: the American Society of Radiologic Technologists (ASRT), the Canadian Association of Medical Radiation Technologists (CAMRT), the College of Radiographers in the United Kingdom, and radiography societies and associations in Asia, Australia, Europe, and Africa. This is an ideal book for radiologic technologists, nuclear medicine technologists, and radiation therapists seeking to get started in research in their profession. Additionally, biomedical imaging engineering technologists, radiologists, and medical imaging physicists may use this as a “guiding principles” textbook.
    Type of Medium: Online Resource
    Pages: XVII, 215 p. 53 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030799564
    DDC: 660.6
    Language: English
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  • 92
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Background of Mulberry: Origin and Distribution, Domestication, Taxonomy, Cytology and Biodiversity -- Cultivation, Utilization and Economic benefits of mulberry in an Indian Context -- Mulberry Breeding for higher leaf Productivity -- Mulberry genome analysis: Current status, challenges, and future perspective -- Relationship between genome size and ploidy level in mulberry -- Transcriptomics: Current status and future prospects for identifying trait specific genes in mulberry -- Proteomics in mulberry -- Current status and importance of DUS testing in Mulberry -- Molecular diagnostics of soil borne and foliar diseases of mulberry: Present trends and future perspectives -- Transgenic Mulberry (Morus spp.) for Stress Tolerance: Current Status, Challenges and Future Perspectives -- Application of mulberry and mulberry silkworm by products for medical use -- Application of green synthesized nanoparticles in sustainable mulberry production: current trends and future perspectives -- Future Perspectives of Mulberry Genomic Research.
    Abstract: This book is the first comprehensive compilation of current knowledge on mulberry (Morus L.) covering botany, cytogenetics, biodiversity, genetics and breeding, tissue culture and genetic transformation, biotic and abiotic stresses, molecular mapping, QTL identification, whole genome sequencing and elucidation on functional genomics. As mulberry is one of the most economically important trees in Asian countries, it has attracted the attention of both academicians as well as industrialists. Being highly heterozygous due to long juvenile life coupled cross pollination among species, the genetics of this important crop species is yet to be unravelled. Nonetheless, the recent success of sequencing the genomes of haploid and diploid domesticated species has ushered in an era of intense molecular and genetic research to understand this crop well for its better utilization for mankind. In this book, efforts have been made to bring together key information on origin and distribution, taxonomy, morphological features, economic importance, abiotic stress responses, disease and pest resilience, current breeding strategies and their constraints, progress and prospects of gene mapping, elucidation of genes controlling metabolic and physiological pathways, and their utilization in crop improvement which are elaborated in about 250 pages over 13 chapters authored by globally leading experts on the species presented. This book is useful to the sericulture community in the world in general and students, teachers, and scientists in the academia for forage and fruit production, genetics, breeding, pathology, entomology, physiology, molecular genetics, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful to seed and biofuel industries.
    Type of Medium: Online Resource
    Pages: XIX, 298 p. 37 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031284786
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 93
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Zoology. ; Biotechnology. ; Zoology. ; Biotechnology. ; Biotechnology.
    Description / Table of Contents: 1. Introduction and history of insect biotechnology -- 2. Why biotechnology needed in Insects? -- 3. Importance and application of biotechnology in insects -- 4. Recent advances in insect biotechnology -- 5. Insect metagenomics -- 6. Molecular signatures of host-pathogen interactions in virus infected Lepidopterans -- 7. Future prospects of insect biotechnology.
    Abstract: This textbook introduces to the fundamentals and applications of insect biotechnology in a concise manner. Global economically important insects such as silkworm, lac or honey bee are in the focus of this text. The book attempts to address all of the latest developments in this growing field such as application of metagenomics and proteomics in mining for genes and enzymes that could be beneficial in diverse industrial and biomedical applications. Further, insects have been established as suitable tool for the production of transgenic products which is discussed in one dedicated chapter. The book targets students and researchers in molecular biology, biotechnology or entomology who want to get familiar with the emerging field of insect biotechnology.
    Type of Medium: Online Resource
    Pages: XII, 136 p. 53 illus., 18 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031267765
    Series Statement: Learning Materials in Biosciences,
    DDC: 590
    Language: English
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  • 94
    Keywords: Fungi. ; Mycology. ; Microbiology. ; Botanical chemistry. ; Biotechnology. ; Plants Development. ; Fungi. ; Microbiology. ; Plant Biochemistry. ; Biotechnology. ; Plant Development.
    Description / Table of Contents: Preface -- Long Term Preservation of Fungal Cultures in All-Russian Collection of Microorganisms (VKM): Protocols and Results -- Confocal Laser and Epifluorescence Microscopy -- Diagnose of Chytid Parasites of Algae in The Plankton -- Sabouraud Agar for Fungal Growth -- FISH, Fluorescence in Situ Hybridization of Uncultured Zoosporic Fungi -- Real-time Quantitative PCR Assay for Counting Uncultured Zoosporic Fungi -- Real-Time PCR Assay in Fungi -- Rapid Identification and Detection of Pathogenic Fungi by Padlock Probes -- Extraction and Characterization of Taxol: An Anticancer Drug from an Endophytic And Pathogenic Fungi -- Recent Advances in Applications of Machine Learning in Fungal Biology -- Fungal Conservation -- TBD -- Loop-Mediated Isothermal Amplification of the Entomopathogenic Fungi, Beauveria bassiana -- Molecular Taxonomy and Multi-Gene Phylogeny of Fungi -- Yeast Isolation Methods from Specialized Habitats -- Assays for the Quantification of Antioxidant Enzymes in Fungi -- Index.
    Abstract: Mycology has an integral role to play in the development of the biotechnology and biomedical sectors. It has become a subject of increasing importance as new fungi and their associated biomolecules are identified. As this discipline comes to the forefront of research in these sectors, the requirement for a consolidation of available research approaches is required. The First Edition of this book has a few basic and applied protocols. With the Second Edition, this book provides consolidated information on recent developments and the most widely used mycological methods available in the fields of biochemistry, biotechnology and microbiology. The methods outlined offer clear and concise directions to the reader and covers both standard protocols and more applied mycological methods. This book provides useful information for undergraduates, post-graduates, and specialists and researchers studying fungal biology.
    Type of Medium: Online Resource
    Pages: VI, 261 p. 24 illus., 15 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030837495
    Series Statement: Fungal Biology,
    DDC: 579.5
    Language: English
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  • 95
    Keywords: Immunology. ; Immune response. ; Pathogenic microorganisms. ; Natural immunity. ; Biotechnology. ; Immunology. ; Antimicrobial Responses. ; Innate Immunity. ; Biotechnology.
    Description / Table of Contents: 1. Antimicrobials in livestock production and its cross-domain dynamics -- 2. Antibiotics and resistance in environment -- 3. Antimicrobials in agriculture and its implications in antimicrobial resistance -- 4. Modern diagnostic tools for rapid detection of multidrug resistance -- 5. The use of antimicrobials in agriculture and socio-economic considerations in a global world -- 6. Epidemiology of microbial infections -- 7. Socioeconomic impact of antimicrobial resistance and their integrated mitigation by One Health approach -- 8. Regulations in antimicrobial drug development: Challenges, and new incentives -- 9. New insights into and updates on antimicrobial agents -- 10. Polyphenols as emerging antimicrobial agents -- 11. Antimicrobial peptides and small molecules as antibiotics substitute -- 12. Molecular mechanisms of antimicrobial resistance in S. aureus biofilms -- 13. Antimicrobial resistance: Meaning and developing realization -- 14. Chemical diversity in fungi: strategies to mitigate antimicrobial resistance -- 15. Phage therapy as an alternative treatment in the fight against AMR: Real-world problems and possible futures -- 16. Omics and in-silico approaches in the surveillance and monitoring of antimicrobial resistance -- 17. Antimicrobial activity of bioactive compounds (Thymoquinone & Eugenol) and its nanoformulations therapeutic potential -- 18. Nanoparticles as a future alternative against multiple drug resistance -- 19. Nano-cargos boarded defensins to combat multi-drug resistance -- 20. Implementation of nano-vehicles to disguise and fight multi-drug resistance -- 21. Silver nanoparticles as potent multi-drug resistant in-corporants in biomedicine -- 22. Role of gold nanoparticles against bacterial multidrug resistance (MDR): An emerging therapeutic revolution -- 23. Carbon nanoparticles: A potential cost-effective approach to counter antimicrobial resistance -- 24. Antimicrobial interfaces as augmentative strategy against antimicrobial resistance -- 25. Nano-Strategies against rising antimicrobial resistance (AMR): Metallic nanoparticles as nano-weapon. .
    Abstract: This book provides an overview of cutting-edge and next-generation research and technologies for combating antimicrobial resistance. Antibiotic-resistant infections are projected to cause 10 million deaths annually by the year 2050. A sustainable, unified approach by researchers, practitioners, policymakers, and the public is urgently needed to stem this trend. This book aims to provide a comprehensive summary of current and future-facing efforts to mitigate the threat of AMR through a One-Health approach. This book is a valuable resource for students, researchers, policymakers, and the public about AMR and novel strategies to combat AMR.
    Type of Medium: Online Resource
    Pages: XII, 577 p. 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841263
    DDC: 571.96
    Language: English
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  • 96
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Molecular biology. ; Genetics. ; Recombinant DNA. ; Biology Technique. ; Biotechnology. ; Molecular Biology. ; Genetics and Genomics. ; DNA Recombination. ; Biological Techniques. ; Biotechnology.
    Description / Table of Contents: 1.The Recombinant DNA technology era -- 2.Vectors: Guide to gene delivery vehicles -- 3.Gene isolation methods: beginner's guide -- 4.Restriction Enzymes-Tools for DNA cloning -- 5.Overview of Gene cloning strategies -- 6.Fundamental techniques of recombinant DNA transfer -- 7.Selection, screening and analysis of recombinant clones -- 8.Recent trends and advances -- 9.Applications of Recombinant DNA technology -- 10.Ethical and safety concerns of recombinant DNA Technology.
    Abstract: This comprehensive guide to gene cloning provides beginning and advanced readers with the background, standard techniques, practical applications, and ethical and safety considerations in the field. A one-stop reference for students, researchers in academia and industry, and anyone interested in a thorough but accessible overview.
    Type of Medium: Online Resource
    Pages: XVII, 169 p. 51 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968519
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 572
    Language: English
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  • 97
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Immunology. ; Biomedical engineering. ; Biotechnology. ; Immunology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: 1. The Musculoskeletal Burden – Where are we now? -- 2. Bacterial Adhesion, Virulence and Biofilm Formation -- 3. Prevention of Infection: Best Practice and Novel Strategies -- 4. Prosthetic Infection: Colonization and Diagnosis -- 5. Soft Tissue Infections -- 6. Incidence, Complications and Novel Treatment Strategies: Diabetic Ulcer of the Limb -- 7. Incidence, Complications and Novel Treatment Strategies: Osteomyelitis -- 8. Incidence, Complications and Novel Treatment Strategies: Joint Arthroplasty -- 9. Incidence, Complications and Novel Treatment Strategies: Massive Bone Tumour Surgery -- 10. Incidence, Complications and Novel Treatment Strategies: Pediatric Spinal Surgery & Management -- 11. War Wounds and Orthopaedic Trauma Devices.
    Abstract: This book gathers international knowledge and contemporary clinical and scientific evidence on infections associated with the musculoskeletal system at a time when we are confronted with significant challenges and uncertainty. A key focus of the book is enhancing and advancing future discovery in the detection, prevention and treatment of musculoskeletal infection. This is an ideal book for physicians, surgeons, research scientists, university students, as well as medical and allied health students.
    Type of Medium: Online Resource
    Pages: VII, 375 p. 41 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030832513
    DDC: 660.6
    Language: English
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  • 98
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Biotechnology. ; Mathematics. ; Civil engineering. ; Biomaterials. ; Computational and Systems Biology. ; Biotechnology. ; Applications of Mathematics. ; Civil Engineering. ; Biomaterials.
    Description / Table of Contents: Chapter1. Adhesion of living cells: Mechanisms of adhesion and contact models (F.M. Borodich, B.A. Galanov, L.M. Keer, and M.M. Suarez-Alvarez) -- Chapter2. Contact problem in indentation measurements of soft, biological and bioinspired materials. Indentation of soft materials, biological cells (I. Sokolov ) -- Chapter 3. Mechanical properties of the cell surface layer measured by contact atomic force microscopy (M. N. Starodubtseva ) -- Chapter4. Capillary adhesion effect in contact interaction of soft materials (I.G. Goryacheva, Yu.Yu. Makhovskaya) -- Chapter 5. Influence of a soft elastic layer on adhesion of rough surfaces (Q. Li, I.A. Lyashenko, R. Pohrt, V.L. Popov ) -- Chapter6. Asymptotic modeling scheme for analysis of bio-inspired fibrillar adhesive interfaces — A short review (I. Argatov ) -- Chapter 7. Spreading of red caviar cells: The knife-cell and the cell-cell adhesive interactions (F.M. Borodich and S.N. Gorb ) -- Chapter 8. Mechanical characterisation of polymeric materials using nanoindentation (H. Gonabadi, A. Yadav and S. Bull ) -- Chapter 9. Indentation tests of biological materials: Theoretical aspects (X. Jin, P. Li and F.M. Borodich ) -- Chapter 10. Contact of sliders with viscoelastic solids (E. Torskaya, F. Stepanov ) -- Chapter 11. Characterisation of an AFM tip bluntness using indentation of soft materials (S. Baqain, F.M. Borodich, and E. Brousseau ) -- Chapter 12.The JKR formalism in applications to problems of adhesive contact (F.M. Borodich ).
    Abstract: This book contains contributions from leading researchers in biomechanics, nanomechanics, tribology, contact mechanics, materials science and applications on various experimental techniques including atomic force microscopy (AFM) for studying soft, biomimetic and biological materials and objects. Biologists, physicists, researchers applying methods of contact mechanics and researchers testing materials using indentation techniques along with many other applied scientists will find this book a useful addition to their libraries. Moreover, several reviews in this book are written as introductions to several important and rather sophisticated research areas such as depth-sensing indentation, studying of biological cells by AFM probes, mechanics of adhesive contact and contact between viscoelastic (hereditary elastic) solids. The book containing new theoretical models, results of experimental studies and numerical simulations, along with reviews of above mentioned areas of contact mechanics in application to biological systems, would be beneficial for researchers in many areas of biology, medicine, engineering, mechanics and biomimetics. .
    Type of Medium: Online Resource
    Pages: XIV, 287 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030851750
    Series Statement: Biologically-Inspired Systems, 15
    DDC: 570.285
    Language: English
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  • 99
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. The Model Legume, Medicago truncatula in the Genomic Era: Speeding Up Discoveries in Legume Biology -- Chapter 2. Genome-Wide Association Studies in Medicago truncatula -- Chapter 3. Tnt1 Insertional Mutagenesis In Medicago truncatula for Gene Function Analysis -- Chapter 4. Fast Neutron Bombardment (FNB)-Induced Mutant Resources in Medicago truncatula -- Chapter 5. Medicago Truncatula as s Model to Decipher Powdery Mildew Resistance in Legumes -- Chapter 6. Transcriptional Networks in Medicago truncatula: Genomic and Functional Overview During Root Nodule Symbiosis -- Chapter 7. Understanding of Root Nodule Development at Level of Systems Biology as Obtained by High Throughput Transcriptomic Approach -- Chapter 8. Whole Genome Sequencing Identifies a Medicago truncatula Tnt1 Insertion Mutant in the VIT8 Gene that is Essential for Symbiotic Nitrogen Fixation -- Chapter 9. Regulation of Leaf Blade Outgrowth: In Medicago truncatula -- Chapter 10. Function of Medicago truncatula WOX Genes and their Diversity -- Chapter 11. Early Stages of Seed Development In Medicago truncatula: Lessons from Genomic Studies -- Chapter 12. Seed Maturation Events in Medicago truncatula: Focus on Desiccation Tolerance -- Chapter 13. Functional Genomic and Genetic Studies of Organ Size Control in Medicago truncatula: An Overview.
    Abstract: This book focuses on the discoveries in M. truncatula genomic research which has been undertaken in the last two decades. Legumes are important for their economic values as food, feed, and fodder and also serve as the pillar of sustainable agriculture because of its biological nitrogen fixation capacity. Medicago truncatula was established as a model legume in the 1990s and has been well adopted as a model internationally since then. M. truncatula is an autogamous, diploid (2n = 16) species with a short generation time, and relatively small genome size (~375 Mbp). The M. truncatula genome was initially sequenced by the International Medicago Genome Annotation Group (IMGAG) in 2011 and has been well-annotated. M. truncatula research benefits from the availability of several genetic and genomic tools, such as gene expression atlas (MtGEA), insertion and neutron bombardment mutant populations, and a HapMap panel containing 384 sequenced inbred lines for genome-wide association studies. This book covers the current status and latest advancements of the M. truncatula genomics and transcriptomics resources along with a glimpse of newly developed tools that makes M. truncatula a front runner model in functional genomic studies.
    Type of Medium: Online Resource
    Pages: XXIV, 159 p. 28 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030907570
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 100
    Keywords: Botany. ; Environment. ; Biotechnology. ; Renewable energy sources. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Plant Science. ; Environmental Sciences. ; Biotechnology. ; Renewable Energy. ; Fossil Fuel.
    Description / Table of Contents: Introduction: values of pollution free atmosphere -- Plant and Algae Classes Recognition, Biomass Production and Potential Source of Biofuel -- Plant and Algae Metabolites Alternative and Clean Source of Energy -- Mechanism and methods of extraction of biofuels -- Metabolic routes to biofuels extraction -- Optimizations on steps involved on biofuel obtainment and their validation -- Economic consideration on biofuel and energy security -- Technical challenges of biofuel obtainment -- Conclusion and Future Perspectives.
    Abstract: This volume discusses how plant and algae organisms play a pivotal role in the transformation of solar energy to essential metabolites, and explores the numerous beneficial roles these metabolites have at an industrial level. It presents information on the utilization of plant and algae for biomass production, and shows how this is a practical option for large scale biofuel production. The book examines how these bio-metabolites can then be used to extract biofuel. Biomass produced from plants and algae can act as the source of feedstock for biofuel production and industrially important compounds. This book also explores that by curtailing culturing cost using wastewater, seawater, and industrial water as a nutrient and water source, biomass becomes an economical energy source. The introductory chapters of the book focus on the appreciative values of a pollution-free atmosphere, with special reference to enhanced greenhouse effect, and then are followed by chapters on the potential of plant and algae as a liquid energy resource. This book targets researchers, graduate students, and energy and fuel industry professionals interested in the plant sciences, biotechnology and renewable energy. .
    Type of Medium: Online Resource
    Pages: XV, 164 p. 21 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030940744
    DDC: 580
    Language: English
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