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  • 11
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    Nature Publishing Group (NPG)
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Van Noorden, Richard -- England -- Nature. 2011 Dec 21;480(7378):426-9. doi: 10.1038/480426a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22193080" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Disasters ; Drug Industry/economics ; Humans ; Physics/trends ; Science/economics/*trends ; Scientific Misconduct ; Sequence Analysis, DNA ; Stem Cells
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 12
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    Nature Publishing Group (NPG)
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wadman, Meredith -- England -- Nature. 2011 Dec 20;480(7378):424-5. doi: 10.1038/480424a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22193077" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Experimentation/*legislation & jurisprudence/standards ; Animals ; Disease Models, Animal ; Hepatitis C/prevention & control ; Humans ; *Pan troglodytes ; Research/*economics ; United States ; Viral Hepatitis Vaccines
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 13
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kutschera, U -- England -- Nature. 2011 Dec 21;480(7378):457. doi: 10.1038/480457c.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22193089" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Biology/*trends ; Humans ; Stem Cells/*cytology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 14
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Margalida, Antoni -- Campion, David -- Donazar, Jose A -- England -- Nature. 2011 Dec 21;480(7378):457. doi: 10.1038/480457b.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22193090" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/*physiology ; Falconiformes/*physiology ; France ; Predatory Behavior/*physiology ; Sanitation/legislation & jurisprudence ; Spain
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 15
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    Nature Publishing Group (NPG)
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Butler, Declan -- England -- Nature. 2011 Dec 20;480(7378):421-2. doi: 10.1038/480421a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22193075" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Containment of Biohazards ; Humans ; Influenza A Virus, H1N1 Subtype/genetics/*physiology ; Laboratories/legislation & jurisprudence/*standards ; Mutation ; Orthomyxoviridae Infections/*transmission/virology ; Safety ; Specimen Handling ; Virology/methods
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 16
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Szathmary, Eors -- New York, N.Y. -- Science. 2011 Dec 23;334(6063):1648-9. doi: 10.1126/science.1209548.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Biological Institute, Eotvos University, 1c Pazmany Peter Setany, Budapest, Hungary. szathmary.eors@gmail.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22194561" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Evolution ; *Cooperative Behavior ; *Genetic Variation ; *Models, Biological
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 17
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Butterfield, N J -- New York, N.Y. -- Science. 2011 Dec 23;334(6063):1655-6. doi: 10.1126/science.1216125.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Earth Sciences, University of Cambridge, Cambridge, UK. njb1005@esc.cam.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22194566" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Nucleus/*ultrastructure ; Eukaryota/*growth & development ; *Fossils
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 18
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2011-12-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Engelhardt, Britta -- New York, N.Y. -- Science. 2011 Dec 23;334(6063):1652-3. doi: 10.1126/science.1216853.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Theodor Kocher Institute, University of Bern, Bern, Switzerland. bengel@tld.unibe.ch〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22194564" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Astrocytes/*metabolism ; Blood-Brain Barrier/*physiology ; Brain/*immunology ; Endothelial Cells/*metabolism ; Female ; Hedgehog Proteins/*metabolism ; Humans ; *Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 19
    Publication Date: 2011-12-24
    Description: Globular fossils showing palintomic cell cleavage in the Ediacaran Doushantuo Formation, China, are widely regarded as embryos of early metazoans, although metazoan synapomorphies, tissue differentiation, and associated juveniles or adults are lacking. We demonstrate using synchrotron-based x-ray tomographic microscopy that the fossils have features incompatible with multicellular metazoan embryos. The developmental pattern is comparable with nonmetazoan holozoans, including germination stages that preclude postcleavage embryology characteristic of metazoans. We conclude that these fossils are neither animals nor embryos. They belong outside crown-group Metazoa, within total-group Holozoa (the sister clade to Fungi that includes Metazoa, Choanoflagellata, and Mesomycetozoea) or perhaps on even more distant branches in the eukaryote tree. They represent an evolutionary grade in which palintomic cleavage served the function of producing propagules for dispersion.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Huldtgren, Therese -- Cunningham, John A -- Yin, Chongyu -- Stampanoni, Marco -- Marone, Federica -- Donoghue, Philip C J -- Bengtson, Stefan -- New York, N.Y. -- Science. 2011 Dec 23;334(6063):1696-9. doi: 10.1126/science.1209537.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Palaeozoology, Swedish Museum of Natural History, Stockholm, Sweden.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22194575" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Evolution ; Cell Division ; Cell Nucleus/*ultrastructure ; Cell Shape ; China ; Embryo, Nonmammalian ; Eukaryota/classification/cytology/*growth & development/ultrastructure ; *Fossils ; Imaging, Three-Dimensional ; Life Cycle Stages ; Mesomycetozoea/classification/cytology/growth & development ; Phylogeny ; Synchrotrons ; Tomography, X-Ray
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 20
    Publication Date: 2011-12-24
    Description: Several groups of tetrapods have expanded sesamoid (small, tendon-anchoring) bones into digit-like structures ("predigits"), such as pandas' "thumbs." Elephants similarly have expanded structures in the fat pads of their fore- and hindfeet, but for three centuries these have been overlooked as mere cartilaginous curiosities. We show that these are indeed massive sesamoids that employ a patchy mode of ossification of a massive cartilaginous precursor and that the predigits act functionally like digits. Further, we reveal clear osteological correlates of predigit joint articulation with the carpals/tarsals that are visible in fossils. Our survey shows that basal proboscideans were relatively "flat-footed" (plantigrade), whereas early elephantiforms evolved the more derived "tip-toed" (subunguligrade) morphology, including the predigits and fat pad, of extant elephants. Thus, elephants co-opted sesamoid bones into a role as false digits and used them for support as they changed their foot posture.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hutchinson, John R -- Delmer, Cyrille -- Miller, Charlotte E -- Hildebrandt, Thomas -- Pitsillides, Andrew A -- Boyde, Alan -- 18768/Arthritis Research UK/United Kingdom -- BB/C516844/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- BB/H002782/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- Arthritis Research UK/United Kingdom -- New York, N.Y. -- Science. 2011 Dec 23;334(6063):1699-703. doi: 10.1126/science.1211437.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Veterinary Basic Sciences and Structure and Motion Laboratory, The Royal Veterinary College, Hatfield, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22194576" target="_blank"〉PubMed〈/a〉
    Keywords: Adipose Tissue/anatomy & histology/physiology ; Animals ; *Biological Evolution ; Biomechanical Phenomena ; Cartilage/anatomy & histology/growth & development ; Elephants/*anatomy & histology/growth & development/physiology ; Female ; Foot/*anatomy & histology/growth & development/physiology ; Foot Joints/anatomy & histology/physiology ; Forelimb ; Fossils ; Hindlimb ; Locomotion ; Microscopy, Electron, Scanning ; Movement ; Osteogenesis ; Sesamoid Bones/*anatomy & histology/growth & development ; Toes/*anatomy & histology/growth & development/physiology ; Tomography, X-Ray Computed
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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