ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 2
    Online Resource
    Online Resource
    Photoprotective Green Pharmacology: Challenges, Sources and Future Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Pharmacology. ; Pharmaceutics. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1: Radiation biology: historical background, sources and complications -- Chapter 2: Algal radioprotective phytochemicals: Sources and potential applications -- Chapter 3: Bio-prospecting of photoprotective compounds in algae -- Chapter 4: Unraveling fungal radioprotectants and their applications -- Chapter 5: Recent advances in metabolomics and molecular genomics for the production of photoprotective compounds -- Chapter 6: Bioprospecting and evolutionary significance of radioprotectors in non-flowering lower plants -- Chapter 7: Radioprotective phytochemicals: diversity, efficacy, application and commercialization -- Chapter 8: Impacts of climate alterations in the biosynthesis of defensive natural products -- Chapter 9: Cancer therapeutics: mechanism of action, radiation toxicity and drug formulation -- Chapter 10: Role of nanotechnology in the development of radioprotective formulations -- Chapter 11: Radioprotective effects of nutraceuticals and food products -- Chapter 12: Bioprospecting of radioprotective compounds in bacterial community -- Chapter 13: Pharmacology of synthetic and natural radioprotactants: application and consequences in cancer therapeutics -- Chapter 14: Immunochemistry: consequences and mechanism of protection in chemotherapeutics -- Chapter 15: Radioprootective therapeutics: recent trends and future applications.
    Abstract: This book illustrates the role of photoprotective and radioprotective metabolites from natural sources. Various classes of radioprotective metabolites derived from cyanobacteria, algae, fungi, bryophytes, pteridophytes, gymnosperms, and higher plants have been explained to reinforce the current knowledge in this field. In addition, the book elucidates the potential applications of these metabolites in pharmaceutics, cosmetics, and biomedical sciences that will help develop commercial products in modern anti-radiation therapeutics. Topics such as stress tolerance environmental strategies, evolutionary tendency, and biosynthetic route of radioprotective compounds for cost-effective large-scale industrial production of the metabolites are also covered in the book. This book will add to the understanding of radioprotective mechanisms and curative measures for various deleterious diseases leading to cancer development. This volume also offers the latest insights into current and upcoming issues that arise from solar and atomic radiations and their amelioration by inherent radioprotective mechanisms of green plants. This book benefits readers from academia, industry, colleges, and research students to better understand the impacts of various radiations and the development of radioprotective green compounds.
    Type of Medium: Online Resource
    Pages: XIII, 264 p. 62 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819907496
    URL: https://doi.org/10.1007/978-981-99-0749-6
    DOI: 10.1007/978-981-99-0749-6
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 3
    Online Resource
    Online Resource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 4
    Online Resource
    Online Resource
    Data Monitoring Committees (DMCs) : Past, Present, and Future (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Description / Table of Contents: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Abstract: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Type of Medium: Online Resource
    Pages: XII, 111 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287602
    URL: https://doi.org/10.1007/978-3-031-28760-2
    DOI: 10.1007/978-3-031-28760-2
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 5
    Online Resource
    Online Resource
    Marine Biomaterials : Therapeutic Potential (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Therapeutics. ; Pharmaceutical chemistry. ; Biomaterials. ; Pharmacology. ; Translational Research. ; Therapeutics. ; Pharmaceutics. ; Biomaterials.
    Description / Table of Contents: Chapter 1. Marine biomaterials: resources, categories and applications -- Chapter 2. Cross-linked marine biopolymers for delivery of therapeutics -- Chapter 3. Chitosan and Chitooligosaccharides: Preparation, Characteristics and their Potential Application as Therapeutic Agents -- Chapter 4. Marine collagen for delivery of therapeutics -- Chapter 5. Marine Biopolymers for delivery of Gene -- Chapter 6. Hydrogel scaffolds based on alginate, gelatin, and 2-hydroxyethyl methacrylate for tissue regeneration -- Chapter 7. Tissue Engineering application of marine based materials -- Chapter 8. Marine biopolymer for theranostic applications -- Chapter 9. Marine biomaterials as carrier of drugs/biomolecules for management of bone disorders -- Chapter 10. Expanding Role of Marine Natural Compounds in Immunomodulation: Challenges and Future Perspectives -- Chapter 11. Marine origin Bioactive Peptides: novel advances in the therapeutic potential.
    Abstract: This book provides updated information on marine-based biomedical carriers and their therapeutic potential. Marine biomaterials and bio-based carriers show wide application in pharmaceutical and biomedical fields to deliver small and large molecules. Biomaterial-based composites, scaffolds, or matrix systems are sound systems for controlled and prolonged drug release in target sites and control the premature release of drugs or bioactive compounds. This book discusses essential topics such as the therapeutic potential of marine collagen, management of bone disorders, gene delivery, natural marine compounds in immunomodulation, theranostic applications, tissue engineering, and regeneration. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. Marine biomaterial-based systems are popular for tissue engineering and biomedical imaging. This book is ideal for industry experts, students, and researchers in pharmaceutical sciences and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 392 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811653742
    URL: https://doi.org/10.1007/978-981-16-5374-2
    DOI: 10.1007/978-981-16-5374-2
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 6
    Online Resource
    Online Resource
    Drug Target Selection and Validation (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drugs Design. ; Medicinal chemistry. ; Molecular biology. ; Pharmacology. ; Pharmaceutics. ; Structure-Based Drug Design. ; Medicinal Chemistry. ; Molecular Biology.
    Description / Table of Contents: Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies – Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery.
    Abstract: The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
    Type of Medium: Online Resource
    Pages: XV, 257 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030958954
    Series Statement: Computer-Aided Drug Discovery and Design, 1
    URL: https://doi.org/10.1007/978-3-030-95895-4
    DOI: 10.1007/978-3-030-95895-4
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 7
    Online Resource
    Online Resource
    Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: Part 1: Quality by Design (QbD) -- Chapter 1. Pharmaceutical Quality by Design (QbD) overview and major elements -- Chapter 2. Fundamentals of design of experiments and optimization: designs for factor screening and data analysis in pre-response surface methodology -- Chapter 3. Fundamentals of design of experiments and optimization: experimental designs in response surface methodology -- Chapter 4. Fundamentals of design of experiments and optimization: data modeling in response surface methodology -- Chapter 5. Quality by Design in pharmaceutical product and process development -- Chapter 6. A Quality by Design update on nano-drug delivery systems -- Chapter 7. Control strategies of solid dosage forms by PAT tools -- Part 2: Analytical Quality by Design (AQbD) -- Chapter 8. Analytical Quality by Design Fundamentals, Compendial and Regulatory Perspectives -- Chapter 9. Analytical Target Profile (ATP) and Method Operable Design Region (MODR) -- Chapter 10: Quality by Design applications to development of analytical methods for quality control of pharmaceuticals -- Chapter 11. Design of Experiments Applied to the Extraction of Active Compounds. .
    Abstract: Written by twenty-five authors from academia, pharmaceutical industry and Pharmacopeias worldwide, this monograph covers the fundamentals and applications of Quality by Design (QbD) and Analytical Quality by Design (AQbD) in a practical and didactic manner. The book starts by describing the motivation and the urgent need for the implementation of the QbD framework in pharmaceutical development, along with the definition of its major elements: Quality Target Product Profile (QTTP), Critical Quality Attributes (CQAs), Critical Process Parameters (CPPs), Critical Material Attributes (CMAs) and the importance of using multivariate methods of Design of Experiments (DOE). The concept of life cycle and regulatory perspectives are discussed. Three chapters are entirely dedicated to DOE theory from screening to optimization designs. Moreover, a comprehensive discussion on modelling and data treatment is presented. Practical aspects of QbD and DOE for pharmaceutical product and process of different dosage forms is included, as well as a practical guide of the input process variables, material attributes, intermediate, and final quality attributes for the most representative pharmaceutical processes. Analytical Quality by Design (AQbD) is also deeply explored, including risk analysis, definitions of Analytical Target Profile (ATP), Method Operable Design Region (MODR) and the life cycle approach, taking into account the compendial and regulatory perspectives. A detailed example of a new chromatographic method for the quality control of a pharmaceutical topical product based on the AQbD procedure is shown. Finally, advanced statistical approaches and DOE methods for extraction studies of bioactive compounds are also presented. The vast amount of information offered in this book provides a comprehensive perspective on QbD, AQbD and DOE principles, essential tools for modern pharmaceutical and analytical development.
    Type of Medium: Online Resource
    Pages: X, 266 p. 62 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315053
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 10
    URL: https://doi.org/10.1007/978-3-031-31505-3
    DOI: 10.1007/978-3-031-31505-3
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 8
    Online Resource
    Online Resource
    Winning Grants (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: Preface -- Abbreviations -- Chapter 1 – Why you need this book and why I wrote it -- Chapter 2 – What you need to do before you write a grant -- Chapter 3 – The idea -- Chapter 4 – Go solo or collaborate? -- Chapter 5 – What the entrepreneur needs to know -- Chapter 6 – The grant package -- Chapter 7 – The main event – writing it -- Chapter 8 – Edit / Polish / Shine / Repeat -- Chapter 9 – Are you ready to submit it? -- Chapter 10 - Post submission steps to win the grant -- Afterthoughts -- Index -- About the Author.
    Abstract: As an academic or a small business owner, you will need to write grants at some point in your career. Writing them though is not enough, what you also need to know is how to win grants. Much has been written about writing grants, the mysterious special ability called ‘grantsmanship’, so it occurred to me that there is a need to come at this differently and spill the beans. The difficulty in getting a grant, in particular an NIH grant like an R01 in the USA is often described, it is competitive and gets tougher every year. Your proposal therefore must stand out, it must connect with the reviewers. This is true for all types of grants, give the reviewer what they want always. But also, you need to connect to the program officer, the committee that ultimately makes funding decisions and you must take care of a myriad of other details outside of the main event which is describing the “science”. This means you cannot rely on just out-writing the competition, it is more than that as you have to out-think, out-strategize and out-schmooze them. If you have been continually funded for decades that is terrific, but if you want to keep being funded there is no guarantee what got you there will keep you there. What was a hot technology 4-5 years ago is not the new thing anymore, you will need to do something different, but what? You therefore need to not only think about writing great grants, you need to put it into practice and win them. Having written and won grants from the NIH and DOD over the past 17 years (and longer by the time you read this) I possess a valuable perspective. Each grant and study section will be different. Whether a big or small grant it does not seem to make a difference the reviewers will critique your efforts, they may not like it, they may reject your ideas or they may love it. You have some small degree of control until the proposal leaves your hands or more correctly you click ‘submit’. You will need to differentiate your grant from the hundreds of others in many ways, but you cannot change who you are, your history so how you describe yourself and team will also have an impact. You could spend hundreds of hours on your proposal or just a day and the outcome might still be the same. This small book is a summary of my own personal experiences and will provide some advice that will help you learn how to do a better job of winning grants. This book is written by a scientist who writes the grants and develops commercial products; Provides a unique perspective on what you need to write better grants; Teaches you how to continually win grants; This book provides examples from the authors own grant applications; The reader will be inspired to start a company to win small business grants.
    Type of Medium: Online Resource
    Pages: XIX, 106 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031275166
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 17
    URL: https://doi.org/10.1007/978-3-031-27516-6
    DOI: 10.1007/978-3-031-27516-6
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 9
    Online Resource
    Online Resource
    Polymeric Micelles: Principles, Perspectives and Practices (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery.
    Description / Table of Contents: 1. Synthesis, self-assembly and functional chemistry of Amphiphilic block copolymers -- 2. Advances in polymer optimisation for enhanced drug delivery -- 3. Dynamics of Micelle Formation -- 4. Types of Polymeric Micelles for Controlled Drug Release -- 5. Drug Solubilization and Drug Release from Polymeric Micelles -- 6. Physical and Analytical Techniques used for the Characterization of Polymeric Micelles -- 7.Stimuli-sensitive polymeric micelles for biomedical applications -- 8.Nucleic acid-based micellar therapy for the treatment of different diseases -- 9. Polymeric micelles in the delivery of therapeutic phytoconstituents -- 10. Diagnostic applications of surface-engineered polymeric micelles -- 11. Ligand conjugated polymeric micelles for targeted delivery of drug payloads in cancer therapy -- 12. Polymeric Micelles in the Delivery of Proteins -- 13. Regulatory aspects for polymeric micelles -- 14. Toxicological and regulatory challenges in design and development of polymeric micelles -- 15. Stability of polymeric micelles and their regulatory status.
    Abstract: This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.
    Type of Medium: Online Resource
    Pages: XV, 294 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903610
    URL: https://doi.org/10.1007/978-981-99-0361-0
    DOI: 10.1007/978-981-99-0361-0
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 10
    Online Resource
    Online Resource
    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Description / Table of Contents: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Abstract: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Type of Medium: Online Resource
    Pages: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...