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  • 1
    Keywords: Biotechnology. ; Plant diseases. ; Microbial ecology. ; Bacteria. ; Biology Technique. ; Biotechnology. ; Plant Pathology. ; Microbial Ecology. ; Bacteria. ; Biological Techniques.
    Description / Table of Contents: Chapter 1. Hairy Roots Biotechnology Unzipped: A Journey of Reality and Promises -- Chapter 2. Hairy Roots as a Source of Tropane Alkaloids -- Chapter 3. Induction, Metabolite Analysis and Transgenesis of Hairy Roots From Coleus Forskohlii -- Chapter 4. Establishment of Hairy Roots of Endangered Himalayan Plantswertiachirata: A Sustainable Alternative to Extraction from Nature -- Chapter 5. A Protocol for the Selection of Spontaneous Variants From Established Catharanthusroseus Hairy Root Cultures -- Chapter 6. Strategies for the Optimization of Culture Conditions for Increasing Metabolite Production Through Hairy Root Cultures. Monoterpenoid Indole Alkaloid Production in Catharanthus Roseus Hairy Roots -- Chapter 7. Protocol for Enhanced Withaferin-a Production in Elicited Withania Somnifera (l.)Dunal Hairy Root Cultures -- Chapter 8. Establishment of Hairy Root Cultures of Pentalinonandrieuxii for the Production of Betulinic Acid -- Chapter 9. Tropane Alkaloid Production by the Establishment Of Hairy Root Cultures of Brugmansia Candida and Elicitation -- Chapter 10. Elicitation as an Essential Strategy For Enhancing Anthraquinone Accumulation In Hairy Root Cultures of Rubia Tinctorum -- Chapter 11. Establishment of Hairy Root Cultures for the Production of Biopharmaceuticals and Optimization of Methods for Recombinant Protein Secretion In The Culture Medium -- Chapter 12. An Improved Protocol for Agrobacterium Rhizogenes-Mediated Transformation of Recalcitrant Plants for Root Biology Studies: A Case Study of Tea Plants (Camellia Sinensis Var. Sinensis) -- Chapter 13 Functional Analysis of Plant Genes Related to Arbuscular Mycorrhiza Symbiosis Using Agrobacterium Rhizogenes-Mediated Root Transformation and Hairy Root Production -- Chapter 14. Functional Characterization of Genes Involved in Legume Nodulation Using Hairy Root Cultures -- Chapter 15. Fluidigm Biomark Diagnostic Panel for Analysis of the Expression of Nicotiana Tabacum Genes, Associated with Alkaloid Synthesis. .
    Abstract: The book discusses the various methods and protocols available in hairy root culture-based research. The utilization of Agrobacterium mediated genetic transformation and establishment of hairy root cultures has paved the way for large-scale secondary metabolite production in medicinal plants. Presenting recent research and offering insights from eminent research groups, the book covers a range of topics related to hairy root-based applications, including (i) establishment of hairy roots and native production of SM (ii) yield enhancement strategies for increased SM production, like elicitation (iii) hairy roots as a tool for value-added applications such as plant-microbe interaction, characterization of plant genes and root biology studies. As such it is an informative guide and experimental manual for researchers in diverse fields of plant biology.
    Type of Medium: Online Resource
    Pages: XIV, 237 p. 47 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811540554
    Series Statement: Rhizosphere Biology,
    DDC: 660.6
    Language: English
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Atoms. ; Molecules. ; Biotechnology. ; Atomic, Molecular and Chemical Physics.
    Description / Table of Contents: Photonic crystals for biomolecule sensing applications -- Recent advances in Surface Plasmon Resonance for biosensing applications and future prospects -- Surface-enhanced Raman Scattering for biology and medicine -- Nanophotonic techniques for single cell analysis -- Biointerface Characterization by Nonlinear Optical Spectroscopy -- Chemiluminescence and its biomedical applications -- Luminescent Conjugated Polymer Dots for Biomedical Applications -- Dark-Field Hyperspectral Imaging (DF-HSI) Modalities for Characterization of Single Molecule and Cellular Processes -- Additive Manufacturing Technologies based on Photopolymerization.
    Abstract: This book summarizes the latest advances in nanophotonics for biomedical applications, including biomolecular sensing and imaging, additive fabrications, and biophotonics. The engineering of nanophotonics will have significant impacts on the life sciences and medicine alike. Given its scope, the book offers a valuable asset for researchers, scientists, engineers, and graduate students in the fields of biomedical engineering, electrical engineering, materials sciences, optics, biology, and medicine.
    Type of Medium: Online Resource
    Pages: V, 282 p. 160 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811561375
    DDC: 660.6
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Radiology. ; Spectrum analysis. ; Pharmaceutical chemistry. ; Nutrition   . ; Biomedical Research. ; Radiology. ; Spectroscopy. ; Pharmaceutics. ; Nutrition.
    Description / Table of Contents: Ch 1: Electron Spin Resonance- An Introdcution -- Ch 2: ESR – Applications in Healthcare and Pharmaceutical Science -- Ch 3: ESR Applications in Paleontology and Geochronology -- Ch 4: ESR Applications in Food Science.
    Abstract: This book introduces the audience with basic theoretical and experimental aspects of Electron Spin Resonance (ESR) Spectroscopy. It further talks about ESR spectroscopy applications in Healthcare & Pharmaceutical Science, Paleontology & Geochronology and Food Science. Mathematical details have been kept to a necessary minimum and emphasis is given to highlight the applications of the technique.
    Type of Medium: Online Resource
    Pages: X, 72 p. 32 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030641986
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 610.72
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Computer vision. ; Radiology. ; Biotechnology. ; Computer Vision. ; Radiology.
    Description / Table of Contents: Introduction -- Preliminaries -- Fuzzy spatial objects (fuzzy geometry and topology, set theoretic operations) -- Mathematical morphology -- Distances and similarities between fuzzy sets -- Machine learning in image processing and understanding -- Fusion -- Spatial relations -- Structural representations.
    Abstract: This book provides a thorough overview of recent methods using higher level information (object or scene level) for advanced tasks such as image understanding along with their applications to medical images. Advanced methods for fuzzy image processing and understanding are presented, including fuzzy spatial objects, geometry and topology, mathematical morphology, machine learning, verbal descriptions of image content, fusion, spatial relations, and structural representations. For each methodological aspect covered, illustrations from the medical imaging domain are provided. This is an ideal book for graduate students and researchers in the field of medical image processing. This book also: Enriches reader understanding of the latest fuzzy sets methods using higher level information (object or scene level) for advanced tasks, such as image understanding Shares many insights into fuzzy spatial objects, including fuzzy geometry and topology as well as set theoretical operations Covers in detail machine learning in image processing and understanding, with special focus on clustering, classification, and basic and advanced fuzzy methods .
    Type of Medium: Online Resource
    Pages: XIII, 302 p. 97 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031194252
    DDC: 660.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Water. ; Hydrology. ; Biotic communities. ; Social sciences. ; Humanities. ; Environmental management. ; Freshwater and Marine Ecology. ; Water. ; Ecosystems. ; Humanities and Social Sciences. ; Environmental Management.
    Description / Table of Contents: Part I. Introduction -- Chapter 1. Southern Baltic Coastal Systems Analysis: Questions, Conceptions and Red Threads -- Chapter 2. Coastal Ecosystems from a Social-Ecological Perspective -- Part II. Ecological Structures and Functions of the German Baltic Sea Coast -- Chapter 3. The Abiotic Background: Climatic, Hydrological and Geological Conditions of the Southern Baltic -- Chapter 4. Geological and Sedimentary Conditions -- Chapter 5. Environmental Conditions at the Coast: The Terrestrial Ecosystems -- Chapter 6. Environmental Conditions at the Coast: Shoreline Ecosystems -- Chapter 7. Ecosystem and Landscape Functions of the Coast: Recent Research Results -- Chapter 8: Benthic Habitats and Their Inhabitants -- Part III. Ecological Structures and Functions of Coastal Water and Offshore Ecosystems -- Chapter 9. Introducing the Ecological Aspects -- Chapter 10. Baltic Sea Aquatic Ecosystems in a Gradient from Land to Open Sea -- Chapter 11. Comparison of Abiotic Parameters and Dominant Primary Producers Between the Two Main Investigation Areas -- Chapter 12. Short-Term Variability, Long-Term Trends and Seasonal Aspects in the Darß-Zingst Bodden Chain -- Chapter 13. Carbon Fluxes/Food-Webs: Effect of Macrophytes on Food Web Characteristics in Coastal Lagoons -- Chapter 14. Ecological Structure in Benthic Habitats of Offshore Waters -- Chapter 15. Patterns of Bioturbation and Associated Matter Fluxes -- Chapter 16. Seasonal Aspects and Short-Term Variability of the Pelagic Offshore Ecosystems -- Chapter 17. Long-Term Trends of the Offshore Ecosystems -- Chapter 18. Nutrient and Limitation Regimes in Coastal Water Ecosystems -- Part IV. Combining the Aspects: Ecosystem Service Assessment -- Chapter 19. The Human Factor: Coastal Social-Ecological Systems -- Chapter 20. Introduction: The Concept of Ecosystem Service Assessment Applied to Coastal Systems -- Chapter 21. The Missing Links in Ecosystem Service Research -- Chapter 22. Eudaimonic Valuation of Cultural Ecosystem Services -- Chapter 23. Economic Valuation of Cultural Ecosystem Services -- Chapter 24. Spatial Ecosystem Service Assessment Across the Land-Sea-Interface -- Chapter 25. Temporal Changes in Aquatic Ecosystem Services Provision: Approach and Examples -- Chapter 26. Assessing Temporal Changes in Ecosystem Service Provisions: Conceiving Future Pathways -- Part V. Synthesis: Assessment as a Tool for Managing Coastal Ecosystems? -- Chapter 27. Applying the Integrated Approach -- Chapter 28. Mechanisms of Ecosystem Service Production: An Outcome of Ecosystem Functions and Ecological Integrity in Coastal Lagoons -- Chapter 29. Ecosystem Service Assessment in European Coastal and Marine Policies -- Chapter 30. Ecosystem Services and Sustainable Development: The Case for Strong Sustainability -- Chapter 31. Concluding Remarks.
    Abstract: This book gives an overall analysis of the current knowledge status about structures, functions, utilization for German Baltic coast ecosystems. The main focus of this book is on the aquatic area, but land/sea interactions as well as river outfalls are included as well. Characteristic for this book is the inclusion of social science aspects. Approximately one third of its extent will be about the ecosystem services. In this segment the results of the last 6 years are presented in which a comprehensive quantification of the social relevance of ecosystems was carried out covering the entire area of the German Baltic Sea. This part builds directly on the results of scientific investigations and are in relation to social ideals. The assessment will not only be economically and ethically but also the mechanisms that are used for the valorisation of the ecosystem services will be evaluated. Both sub-areas, the classic natural science part as well as the part of social science aspects, deal with the changes caused by increasing anthropogenic influence and social (including demographic) changes. This will be among others in the sense of an exemplary historical outline. The final chapter of the synthesis therefore not only presents a summary of the level of knowledge gained and a deduction of the research needs. It further contains a presentation of the application aspects resulting from the analysis of the social relevance gained from basic scientific research. The book is aimed at scientists (and students) of natural, life and social sciences, analysing functioning and structures of coastal ecosystems with regard to sustainable use and nature protection, including aspects of coastal protection. Besides, it is thought to become a reference for all levels of decision makers and stakeholders in coastal and marine management of the Baltic and North Sea region, providing also a blueprint for system analysis respecting for societal as well as biological aspects world-wide.
    Type of Medium: Online Resource
    Pages: XV, 387 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031136825
    Series Statement: Ecological Studies, Analysis and Synthesis, 246
    DDC: 577.6
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical policy. ; Quality of life. ; Biomedical Research. ; Health Policy. ; Quality of Life Research.
    Description / Table of Contents: Foreword: Challenges & Opportunities for LGBT Populations and Cancer in Global Oncology -- Introduction -- Africa -- A Double Dose Of Stigma – Being Gay And Living With Cancer In Kenya -- Sexual Orientation, Gender Identity and Cancer in South Africa -- Americas -- Making the Situation of TLGBI People around Cancer visible: Observations from the Andean Region -- Cancer Care Challenges for the LGBT Population in Brazil -- Cancer and the SGM Population in Canada and the United States of America -- South-East Asia -- The South-East Asia Region: Societal Conditions for LGBT Health and Cancer Research -- Europe -- Foreword: The Eurocentralasian Lesbian* Community Perspective on Cancer and LBQ women: Advocating for more Research and Activism Collaboration -- LGBT+ and Cancer in the WHO European Region: Current Situation in 12 Eastern European and Central Asian Countries -- Sexual and Gender Minorities and Cancer in Germany: The Striking Absence of Understanding their Cancer-related Needs -- LGBT Populations and Cancer in the UK -- Eastern Mediterranean -- LGBT Populations and Cancer in the Eastern Mediterranean Region: Insights and Challenges with a Focus on Lebanon -- Western Pacific -- LGBT Populations and Cancer in Australia and New Zealand -- Challenges in Cancer Control Confronting the LGBT Population in China: Health Risks, Unique Barriers, and Unmet Needs -- What Have We Learned about Cancer and the Global LGBT Community? -- Index.
    Abstract: Lesbian, Gay, Bisexual, and Transgender (LGBT) also known as sexual and gender minority (SGM) populations have been the focus of global attention. Most importantly, LGBT populations have been addressed in the context of human rights in multiple reports and other activities by the United Nations and other international organizations. There is great variation among countries in the recognition of LGBT individuals’ human rights. A global focus on LGBT populations’ health is still limited, with the notable exception of HIV research. This book on LGBT populations and cancer in the global context is, therefore, an important step in that it will broaden the focus on LGBT populations’ health. Globally, cancer is the second leading cause of death. Cancer morbidity and mortality are increasing disproportionately among populations in lower-income countries. A review conducted by the World Health Organization (WHO) found that of the 82% of member states (158) countries, only 35% of the national cancer control plans addresses vulnerable population, including LGBT populations. These findings reflect an increasing awareness about equity when addressing cancer prevention and control, including LGBT populations. This book addresses LGBT populations’ cancer burden across countries that range from high- to low-income countries to support efforts in diverse countries that are working towards reducing LGBT populations’ cancer burden. It documents place-specific challenges that impede progress towards reducing the LGBT cancer burden as well as critically assesses the variation in cancer control efforts that target LGBT populations and cancer to support progress at a global scale. This book includes six sections that cover the six WHO regions, with each chapter written by an author from the specific region s/he is covering. Each chapter makes use of a template that contextualizes the region, local data collection/availability, risk factors, cancer prevention, detection, diagnosis, treatment, and survivorship.
    Type of Medium: Online Resource
    Pages: X, 335 p. 3 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065859
    DDC: 610.72
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Medical genetics. ; Cancer. ; Lipids. ; Biomedical Research. ; Pharmacology. ; Medical Genetics. ; Cancer Biology. ; Lipidology.
    Description / Table of Contents: Preface -- Introduction of Druggable Lipid Signaling Pathway -- Biosynthetic Enzymes of Membrane Glycerophospholipid Diversity as Therapeutic Targets for Drug Development -- Druggable Prostanoid Pathway -- Targeting Leukotrienes as a Therapeutic Strategy to Prevent Comorbidities Associated with Metabolic Stress -- Epoxy Fatty Acids are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation -- Druggable Sphingolipid Pathway -- Druggable Lysophospholipid Pathway -- Druggable targets in endocannabinoid signaling -- Drugging the phosphoinositide 3-kinase (PI3K) and phosphatidylinositol 4-kinase (PI4K) family of enzymes for treatment of cancer, immune disorders, and viral/parasitic infections -- Druggable Lipid GPCRs: Past, Present, and Prospects. .
    Abstract: This edited work presents a series of reviews focusing on Druggable Lipid Signaling Pathways. It enables researchers in both academic institutions and industry as well as physicians to understand historical aspects of lipid signaling and future directions of drug discovery targeting lipid signaling pathways. This book provides 9 pathways including acyltransferases, prostanoids, leukotrienes, epoxy fatty acids, sphingolipids, lysophospholipids, endocannabinoids, phosphoinositides, and lipid GPCRs. Readers will discover the importance of each lipid signaling pathway that contributes to broad range of diseases including neurological and neuropsychiatric diseases, pain, metabolic syndromes, cardiovascular diseases, cancer, dermatological diseases, fibrosis, inflammation, etc. Also, readers will recognize that many drugs targeting lipid signaling have been clinically used. Drugs currently under development are also discussed in each chapter, which includes some information about clinical trials and strategic drug designs. .
    Type of Medium: Online Resource
    Pages: VI, 260 p. 33 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506216
    Series Statement: Advances in Experimental Medicine and Biology, 1274
    DDC: 610.72
    Language: English
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  • 8
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Cytology. ; Nanoscience. ; Biotechnology. ; Cell Biology. ; Nanophysics.
    Description / Table of Contents: Chapter 1: Introduction: Fluorescent materials for cell imaging -- Chapter 2: Semiconductor quantum dots for cell imaging -- Chapter 3: Carbon nanodots for cell imaging -- Chapter 4: Silicon nanoparticles for cell imaging -- Chapter 5: Fluorescent metal nanoclusters for bioimaging -- Chapter 6: Lanthanide-based upconversion nanoparticles for bioimaging applications -- Chapter 7: Conjugated polymers and polymer dots for cell imaging -- Chapter 8: Aggregation-induced emission (AIE) probes for cell imaging -- Chapter 9: Luminescent coordination compounds for cell imaging.
    Abstract: This book focuses on the latest fluorescent materials for cell imaging. Cell imaging is a widely used basic technique that helps scientists gain a better understanding of biological functions through studies of cellular structure and dynamics. In the past decades, the development of a variety of new fluorescent materials has significantly extended the applications of cellular imaging techniques. This book presents recently developed fluorescent materials, including semiconductor quantum dots, carbon dots, silicon nanoparticles, metal nanoclusters, upconversion nanoparticles, conjugated polymers/polymer dots, aggregation-induced emission (AIE) probes, and coordination compounds, used for various cellular imaging purposes. It will appeal to cell biologists and other researchers in academia, industry and clinical settings who are interested in the technical development and advanced applications of fluorescence imaging in cells, tissues and organisms to explore the mechanisms of biological functions and diseases.
    Type of Medium: Online Resource
    Pages: V, 247 p. 140 illus., 128 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811550621
    DDC: 660.6
    Language: English
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  • 9
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Animal migration. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Biodiversity. ; Animal Migration.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. European pearl mussel: background information and literature review -- Chapter 3. Materials and methods -- Chapter 4. Results -- Chapter 5. Discussion -- Chapter 6. Conclusions.
    Abstract: The monograph focuses on the European freshwater pearl mussel Margaritifera margaritifera, which is an endangered bivalve species. Most of its populations in the Russian section of the Baltic Sea basin had never been studied, although they were known in the past to the pearl fishers. “Rediscovery” included search for the previously unknown populations, revealing the facts of population extinctions, analysis of negative impacts, elaboration of conservation measures, and revealing of regularities in distribution. Patterns of land use and river management were analyzed. The procedure of “rediscovery” was applied for other animal species of Northwest Russia, which are threatened on a global scale – thick-shelled mussel, Unio crassus; curlew Numenius arquata; black-tailed godwit, Limosa limosa; Northern Lapwing, Vanellus vanellus; European mink, Mustela lutreola; pond bat, Myotis dasycneme; Atlantic sturgeon, Acipenser sturio; and broad-clawed crayfish, Astacus astacus. The methods and principles of conservation studies were discussed. The obtained data were analyzed with respect to current global change of biosphere. The book will appeal to specialists dealing with conservation studies and activities such as red lists, river protection, and conservation of endangered species. Moreover, a part of the book represents an interest for biogerontology as it presents discredit of the popular concept on “negligible senescence.” The data on distribution of some animals in Russia will be interesting in terms of zoology and biogeography, as they are not yet sufficiently represented in the international editions. The book can be used as supplemental reading for courses in biological invasions, ecology and conservation, and biodiversity. The work also contains chapters on global processes (deforestation, desertification, river degradation) and can therefore also be used for general courses in environmental sciences.
    Type of Medium: Online Resource
    Pages: XI, 246 p. 88 illus., 87 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030662554
    DDC: 577.6
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    DDC: 610.72
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Evolution (Biology). ; Biodiversity. ; Animal culture. ; Plant genetics. ; Climatology. ; Freshwater and Marine Ecology. ; Evolutionary Biology. ; Biodiversity. ; Animal Science. ; Plant Genetics. ; Climate Sciences.
    Description / Table of Contents: Part I: Introduction -- Marine Population Genomics: Challenges and Opportunities -- Part II: Marine Microbes -- Part III: Genetic Diversity, Population Structure, and Biogeography -- Population Genomics of Marine Zooplankton -- Population Genomics of Early-Splitting Lineages of Metazoans -- Population Genomics and Biogeography of the Northern Acorn Barnacle (Semibalanus balanoides) Using Pooled Sequencing Approaches -- Part IV: Seascape Genomics -- Seascape Genomics: Contextualizing Adaptive and Neutral Genomic Variation in the Ocean Environment -- Part V: Adaptation, Acclimation, and Speciation -- Clinal Adaptation in the Marine Environment -- The Population Genomics of Parallel Adaptation: Lessons from Threespine Stickleback -- Mechanisms of Adaptive Divergence and Speciation in Littorina saxatilis: Integrating Knowledge from Ecology and Genetics with New Data Emerging from Genomic Studies -- Ecological Speciation in Corals -- Environmental Epigenomics and Its Applications in Marine Organisms -- Part VI: Protection, Conservation, and Management of Marine Organisms -- Marine Invasion Genomics: Revealing Ecological and Evolutionary Consequences of Biological Invasions -- Population Genomics Applied to Fishery Management and Conservation -- Marine Conservation and Marine Protected Areas -- Index.
    Abstract: Population genomics has provided unprecedented opportunities to unravel the mysteries of marine organisms in the oceans' depths. The world's oceans, which make up 70% of our planet, encompass diverse habitats and host numerous unexplored populations and species. Population genomics studies of marine organisms are rapidly emerging and have the potential to transform our understanding of marine populations, species, and ecosystems, providing insights into how these organisms are evolving and how they respond to different stimuli and environments. This knowledge is critical for understanding the fundamental aspects of marine life, how marine organisms will respond to environmental changes, and how we can better protect and preserve marine biodiversity and resources. This book brings together leading experts in the field to address critical aspects of fundamental and applied research in marine species and share their research and insights crucial for understanding marine ecosystem diversity and function. It also discusses the challenges, opportunities and future perspectives of marine population genomics. .
    Type of Medium: Online Resource
    Pages: XVI, 456 p. 75 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030379360
    Series Statement: Population Genomics,
    DDC: 577.6
    Language: English
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  • 12
    Keywords: Biotechnology. ; Food science. ; Microbiology. ; Biotechnology. ; Food Science. ; Microbiology.
    Description / Table of Contents: Part 1. Microalgae in Food Product Development -- Chapter 1. Food and high value products from microalgae: market opportunities and challenges -- Chapter 2. Algae as a mainstream food ingredient: demand and supply perspective -- Chapter 3. Microalgae pigments: a source of natural food color -- Chapter 4. Algal biotechnology: a sustainable route for omega-3 fatty acids and carotenoids production -- Part 2. Microalgae in Health Product Development -- Chapter 5. Microalgae in human health and medicine -- Chapter 6. Astaxanthin production from microalgae -- Chapter 7. Microalgae nutraceuticals: the role of lutein in human health -- Part 3. Microalgae for Cosmetic Formulations -- Chapter 8. Algae and Aging -- Chapter 9. Extracts and bioactives from microalgae (sensu stricto): opportunities and challenges for a new generation of cosmetics -- Part 4. Other High Value Application -- Chapter 10. Microalgae as Vaccine Delivery System to Aquatic Organisms -- Chapter 11. Microalgal as a sustainable source for bioplastic -- Chapter 12. Microalgae as biofertillizer in modern agriculture -- Part 5. Biomass Production -- Chapter 13. Microalgae biomass production, drying and storage -- Chapter 14. Microalgal carbohydrate and proteins: synthesis, extraction, application and challenges -- Chapter 15. Pretreatment and lipid extraction from wet microalgae: Challenges, potential and application for industrial scale application.
    Abstract: "Microalgae Biotechnology for Food, Health and High Value Products” presents the latest technological innovations in microalgae production, market status of algal biomass-based products, and future prospects for microalgal applications. It provides stimulating overviews from different perspectives of application that demonstrate how rapidly the commercial production of microalgae-based food, health and high value products is advancing. It also addresses a range of open questions and challenges in this field. The book highlights the latest advances of interest to those already working in the field, while providing a comprehensive overview for those readers just beginning to learn about the promise of microalgae as a sustainable source of both specialty and commercial products. It offers a valuable asset for commercial algae producers, algae product developers, scientific researchers and students who are dedicated to the advancement of microalgae biotechnology for applications in health, diet, nutrition, cosmetics, biomaterials etc. .
    Type of Medium: Online Resource
    Pages: X, 483 p. 91 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811501692
    DDC: 660.6
    Language: English
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  • 13
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Nanotechnology. ; Cancer. ; Stem cells. ; Diseases. ; Biotechnology. ; Nanotechnology. ; Cancer Biology. ; Stem Cell Biology. ; Diseases.
    Description / Table of Contents: Chapter 1.Current Advances in Nanotechnology and Medicine -- Chapter 2. Least Explored Small Wonders: Nano-biotechnology -- Chapter 3. Modern Approaches in Nanomedicine for neuroAIDS and CNS drug delivery -- Chapter 4. Nanobiotechnology: Paving the way to personalized medicine -- Chapter 5. Nanomedicine in cancer stem cell therapy -- Chapter 6. Nanobiosensor: Current Trends and Applications -- Chapter 7. Transition Metal Oxide Nanoparticles: A New Horizon in Cancer Treatment -- Chapter 8. Nanomedicine meets microRNA expression and function in prostate cancer -- Chapter 9. Biomedical applications of Viral Nanoparticles in vaccine therapy -- Chapter 10. HIV: Biology to Nanomedicine -- Chapter 11. Current Advances in Phage Inspired Nanocarriers Based Therapy -- Chapter 12. Nanophytotherapeutic potential of Essential Oils against Candida infections -- Chapter 13. Molecular tests for the Diagnosis of Tuberculosis: Nanodiagnostics Approaches -- Chapter 14. Molecular Mechanisms of drug resistance in Mycobacterium tuberculosis: Role of nanoparticles against Multi-Drug Resistant tuberculosis (MDR-TB) -- Chapter 15. Nano-Mass spectrometry (nano-MS) based lipidomics -- Chapter 16. Techniques to understand Mycobacterial Lipids and use of Lipid Based Nanoformulations for Tuberculosis Management -- Chapter 17. Recent trends and challenges in Patches for cardiac tissue reengineering: role of Nanomaterials -- Chapter 18. Cyclic dinucleotides: Big roles of small molecules and its role in nanotechnology and medicine -- Chapter 19. Antibodies: Biology to Therapeutics and its role in nanomedicine -- Chapter 20. Nanotoxicology in Medicine -- Chapter 21. Antibody-targeted nanoparticles for cancer treatment -- Chapter 22. Nanoparticle mediated combined photothermal and photodynamic therapy -- Chapter 23. Nanotechnology based devices and its applications in medicine- Chapter 24. Opportunities in clinical translation and commercialization of nanomedicine. .
    Abstract: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology. .
    Type of Medium: Online Resource
    Pages: XX, 517 p. 90 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813298989
    DDC: 660.6
    Language: English
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  • 14
    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Enzymology. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Enzymology. ; Nanotechnology.
    Description / Table of Contents: Immobilization: Then and Now -- Cell immobilization strategies for tissue engineering: Recent trends and future perspectives -- Strategies and advancement in growth factor immobilizable ECM for tissue engineering -- Prospects Of Cell Immobilization In Cancer Research And Immunotherapy -- Nano systems for repairing retinal degeneration -- Systemic drug delivery to the posterior segment of the eye: Overcoming blood-retinal barrier through smart drug design and nanotechnology -- The effects of irradiation with cold atmospheric-pressure plasma on cellular function -- Immobilization of biomolecules on plasma functionalized surfaces for biomedical applications -- A wide portray of Upconversion-nanoparticles: surface modification for bio-applications -- Advances in Amphiphilic Assemblies and its Immobilization in Room Temperature Supercooled Matrices. .
    Abstract: This book delves into the field of immobilizing biologically active and non-active molecules. It discusses the designing strategy of immobilization and the current state-of-the-art applications for advancing biomedical, agricultural, environmental and industrial practices. It focuses on aspects ranging from fundamental principles to current technological advances at multi-scale levels (macro, micro, and nano) which are suitable for cell, enzyme, and nano-catalyst based applications. Written by experts from across the globe, the contents deal with illustrated examples of molecular and cellular interactions with materials/scaffolds and discussions on factors that can affect the functionality and yield of the process. With its discussions on material science, design of delivery vehicles, separation science, additive manufacturing, agriculture and environmental science, this book will be a useful reference for researchers across multiple disciplines.
    Type of Medium: Online Resource
    Pages: X, 666 p. 143 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811579981
    Series Statement: Gels Horizons: From Science to Smart Materials,
    DDC: 660.6
    Language: English
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  • 15
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biochemistry. ; Genetics. ; Biomedical Research. ; Biochemistry. ; Genetics and Genomics.
    Description / Table of Contents: Central dogma of molecular biology -- Impact of chromatin structure -- Epigenetics enables gene expression -- Gene regulation in the context of nuclear architecture -- Core promoter -- TATA box and other core promoter elements -- Genome-wide core promoter identification -- TFIID and Mediator as paradigms of multi-protein complexes -- Site-specific transcription factors and their domains -- Classification of transcription factors -- Activation of transcription factors -- Programing cellular differentiation by transcription factors -- Inflammatory signaling via NF-KB -- Sensing cellular stress via p53 -- The nuclear receptor superfamily -- Molecular interactions of nuclear receptors -- Physiological role of nuclear receptors -- Next-generation sequencing -- Gene regulation in the context of Big Biology -- Exploring genome-wide transcription factor binding -- Integrating epigenome-wide datasets -- Cytosines and their methylation -- Histone modifications -- Gene regulation via chromatin modifiers -- Sensing energy metabolism via chromatin modifiers -- Epigenetics and chromatin -- Genome-wide understanding of epigenetics -- CTCF and genetic imprinting -- Epigenetics in health and disease -- Nucleosome positioning at promoters -- Chromatin remodeling -- Transcriptional dynamics in the presence of chromatin -- Organization of the nucleus -- Non-coding RNAs -- miRNAs and their regulatory potential -- Long ncRNAs -- Enhancer RNAs.
    Abstract: This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation.
    Type of Medium: Online Resource
    Pages: XVI, 149 p. 71 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030523213
    DDC: 610.72
    Language: English
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  • 16
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Geography. ; Environment. ; Power resources. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Regional Geography. ; Environmental Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Intro: Navigating Patagonian freshwaters- and this book -- 1: Are freshwaters wetlands? -- 2: Patagonian Andean lakes and climate change -- 3: Current state and recent changes of glaciers in the Patagonian Andes (35 °S to 55°S) -- 4: Biogeographical patterns of Patagonian freshwater microbiota -- 5: Extreme freshwater ecosystems from Patagonia: The Copahue-Agrio system -- 6: Mercury in aquatic systems of North Patagonia: sources, processes and trophic transfer -- 7: Diversity patterns across aquatic communities from peat bogs -- 8: Hydrologic Systems, water uses and emerging conflicts around freshwater availability in Patagonia -- 9: Land-use effects on aquatic ecosystems: An overview of environmental impacts and tools for ecological assessment -- 10: Patagonian wetlands: vertientes, vegas, mallines,turberas and lagunas -- 11: Fish and fisheries of the Patagonian steppe -- 12: Invasive species: The case of Didymosphenia geminata in Neuquén Province -- 13: Influence of the fish introduction in lakes of the arid Patagonia -- 14: Patagonian cultural limnology: knowledge and water management in Mapuche rural communities -- 15: Political Ecology, water valoration and Water Law deliberation in the Province of Tierra del Nacional de Tierra del Fuego -- 16: Freshwater systems in protected areas in Patagonia -- 17: Amphibians and waterbirds as bridges to conserve aquatic and terrestrial habitat in Patagonia -- 18: Integrated long term conservation strategies to recover the critically endangered Hooded Grebe (Podiceps gallardoi),an endemic waterbird of Austral Patagonia -- Conclusion: Reaching out for the UNDP Sustainable Development Goals in Patagonia.
    Abstract: The Freshwaters of Patagonia adopts a socioecological approach, in which experts from across Patagonia review recent, scientifically rigorous literature and data of their own, thus synthesizing the current knowledge directly relevant to understand the present state and future trends of icefields, freshwater and wetland ecosystems in this region. The book’s organization into three parts provides a studied and comprehensive view on the patterns and processes of the various ecosystems in Patagonia, and describes the sociological aspects of freshwater ecosystems, as well as characterizes the conservation of the freshwater and wetland ecosystems, in Patagonia. The chapters offer a broad, state-of-the-art overview of the current status of glaciers, freshwater and wetland ecosystems of this region, as well as studies of both local and large scale biodiversity patterns, and study cases of extreme and naturally polluted environments.The volume concludes with the current status of Patagonian freshwaters, and discusses the scientific, legal and administrative tools aimed at their sustainable management within the framework of the UNEP Sustainable Development Goals 2030 Agenda. A broad audience of students, scientists, engineers, environmental managers, and policy makers will be interested in this volume.
    Type of Medium: Online Resource
    Pages: XI, 541 p. 104 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031100277
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577.6
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Stem cells. ; Hematology. ; Regenerative medicine. ; Biotechnology. ; Stem Cell Biology. ; Hematology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Hematopoietic Stem Cells -- Mesenchymal Stem Cells -- Cord Blood Stem Cells -- Neural Stem Cells and Their Niche -- Skeletal Muscle Stem Cells -- Heart Muscle Tissue Engineering -- Induced Pluripotent Stem Cells -- Epigenetics of Somatic Cell Reprogramming -- Human Pluripotent Stem Cells and Neural Regeneration -- Dopaminergic Neuron-Related Stem Cells -- Liver Disease Modelling -- Organoids in Developmental Biology Research and Application -- Extracellular Vesicles -- Ethics in Stem Cell Applications.
    Abstract: This textbook describes the biology of different stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal cord blood, neural and muscle stem cells and also covers induced pluripotent stem cells and their applications. Further, it includes chapters on organoids, stem-cell based disease modelling, extracellular vesicles and one chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on lectures of the international master program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and participation of collaborating professors from Tongji University Shanghai, the book is a valuable source for students, postdocs and researchers, who would like to have introductory chapters on stem cell biology. It also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.
    Type of Medium: Online Resource
    Pages: XIV, 242 p. 37 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339234
    Series Statement: Learning Materials in Biosciences,
    DDC: 660.6
    Language: English
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  • 18
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Engineering design. ; Heart Surgery. ; Control engineering. ; Robotics. ; Automation. ; Biotechnology. ; Engineering Design. ; Cardiac Surgery. ; Control, Robotics, Automation.
    Description / Table of Contents: Chapter 1. Evolution of Artificial Heart Technology -- Chapter 2. Mechanisms of Heart Failure -- Chapter 3. Basis of Artificial Heart Technologies -- Chapter 4. Artificial Heart: Rotary Pump -- Chapter 5. Artificial Heart: Volume-Displacement Pump -- Chapter 6. Total Artificial Heart -- Chapter 7. Evaluation of Artificial Hearts -- Chapter 8. Selection of Artificial Heart Devices -- Chapter 9. Therapy Management of VADs -- Chapter 10. Challenges of Artificial Heart Devices -- Chapter 11. A Primary Study for Biocompatible Ventricular Assist Devices.
    Abstract: This book provides a comprehensive introduction to artificial hearts, summarizing the latest advances in basic technologies, design, evaluation, and management. Featuring 11 chapters, it discusses the origins of the artificial heart, the mechanisms of heart failure, and the principles of artificial heart technologies. Further, it offers an overview of rotary pumps and volume-displacement pumps, and addresses total artificial hearts. Lastly, the book covers evaluation, selection, therapy management, challenges, and the latest innovations. Given its scope, it is a valuable resource for researchers and technicians in the area of biomedical engineering, as well as surgeons.
    Type of Medium: Online Resource
    Pages: XV, 212 p. 37 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811543784
    DDC: 660.6
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Biochemistry. ; Physiology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Biochemistry. ; Physiology.
    Description / Table of Contents: Preface -- Part 1 Basics on coenzyme Q -- Introduction. The current coenzyme Q science and knowledge -- Molecular structure, biosynthesis, and distribution of coenzyme Q -- Coenzyme Q function in mitochondria -- Extramitochondrial coenzyme Q10 in aging -- Regulation of the synthesis of Coenzyme Q10 -- Part 2 Coenzyme Q in aging studies -- Coenzyme Q and aging in C. elegans -- Coenzyme Q and aging in the fruit fly Drosophila melanogaster -- The aging process and coenzyme Q: clk-1 mouse models -- Reduced coenzyme Q10 decelerates senescence and age-related hearing loss in senescence-accelerated mice by activating mitochondrial functions -- Part 3 Age-related diseases and coenzyme Q -- Coenzyme Q, mtDNA and mitochondrial dysfunction during aging -- Coenzyme Q10 and metabolic syndrome -- Coenzyme Q and age-related neurodegenerative disorders: Parkinson and Alzheimer diseases -- Immunosenescence and CoQ10 -- Coenzyme Q10 in fertility and reproduction -- Part 4 Prolongevity effectors and Coenzyme Q -- Calorie restriction, longevity and coenzyme Q -- Age dependent changes of coenzyme Q levels and its induction in experimental systems -- Effects of coenzyme Q10 supplementation on elderly people -- Index.
    Abstract: This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ10 is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging. The book is organized in four sections. The first offers an overview of the function of CoQ10, highlighting the two main functions of CoQ10 in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. The second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ on longevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. The final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ10 levels by induction of synthesis or by supplementation. Coenzyme Q in Aging benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process.
    Type of Medium: Online Resource
    Pages: XII, 369 p. 50 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030456429
    DDC: 610.72
    Language: English
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  • 20
    Keywords: Medicine Research. ; Biology Research. ; Microbial ecology. ; Biotic communities. ; Agriculture. ; Industrial microbiology. ; Biomedical Research. ; Microbial Ecology. ; Ecosystems. ; Agriculture. ; Industrial Microbiology.
    Abstract: The book explores the challenges and opportunities associated with high-altitude agro-ecosystems and the factors that influence them. It discusses the various indigenous agricultural practices and approaches, as well as the microbiology of mountain & hill agro-ecosystems, providing a comprehensive overview of the various factors that control the microbiome at high altitudes. The contributions examine microbiological advances, such as use of “omics” technologies for hill agriculture and environmental sustainability, and explore the use of nanotechnology for agricultural and environmental sustainability at higher altitudes. The book also describes various aspects of low-temperature microbiology in the context of high-altitude farming and environmental sustainability.
    Type of Medium: Online Resource
    Pages: XIII, 491 p. 62 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811519024
    Series Statement: Rhizosphere Biology,
    DDC: 610.72
    Language: English
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  • 21
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Reproductive health. ; Cytology. ; Biomedical Research. ; Reproductive Medicine. ; Cell Biology.
    Description / Table of Contents: Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases -- Ch 2: Sertoli cells: immunology and spermatogenesis -- Ch 3: Innate immunity and spermatogenesis -- Ch 4: Cell apoptosis and spermatogenesis -- Ch 5: Transcriptional regulation of spermatogenesis -- Ch 6: Sertoli cell cytoskeleton and spermatogenesis -- Ch 7: Leydig cell and spermatogenesis -- Ch 8: Cross-talk of cell junctions to support spermatogenesis -- Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis -- Ch 10: Regulation of the blood-testis barrier by basement membrane laminin-α2 chain -- Ch 11: Regulation of spermatogenesis by collagens -- Ch 12: Androgen regulation of spermatogenesis -- Ch 13: Use of molecular modeling to study spermatogenesis -- Ch 14: Acrosome biogenesis during spermatogenesis -- Ch 15: Stem cells and spermatogenesis -- Ch 16: Advances in our understanding of spermatogenesis in humans -- Ch 17: Leydig cell function in aging men -- Ch 18: Regulation of human spermatogenesis.
    Abstract: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
    Type of Medium: Online Resource
    Pages: X, 319 p. 44 illus., 40 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030777791
    Series Statement: Advances in Experimental Medicine and Biology, 1381
    DDC: 610.72
    Language: English
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  • 22
    Keywords: Medicine Research. ; Biology Research. ; Cardiovascular system. ; Physiology. ; Cardiology. ; Clinical biochemistry. ; Biomedical Research. ; Cardiovascular Physiology. ; Cardiology. ; Medical Biochemistry.
    Description / Table of Contents: Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure.
    Abstract: This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.
    Type of Medium: Online Resource
    Pages: XVIII, 452 p. 71 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031149528
    Series Statement: Advances in Biochemistry in Health and Disease, 24
    DDC: 610.72
    Language: English
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  • 23
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomedical engineering. ; Radiology. ; Bioinformatics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Radiology. ; Computational and Systems Biology.
    Description / Table of Contents: Deep Learning in Medical Image Analysis -- Medical Image Synthesis via Deep Learning -- Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation -- Deep Learning Computer Aided Diagnosis for Breast Lesion in Digital Mammogram -- Decision support system for lung cancer using PET/CT and microscopic images -- Lesion Image Synthesis using DCGANs for Metastatic Liver Cancer Detection -- Retinopathy analysis based on deep convolution neural network -- Diagnosis of Glaucoma on retinal fundus images using deep learning: detection of nerve fiber layer defect and optic disc analysis -- Automatic segmentation of multiple organs on 3D CT images by using deep learning approaches -- Techniques and Applications in Skin OCT Analysis -- Deep Learning Technique for Musculoskeletal Analysis -- Index.
    Abstract: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
    Type of Medium: Online Resource
    Pages: VIII, 181 p. 131 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331283
    Series Statement: Advances in Experimental Medicine and Biology, 1213
    DDC: 660.6
    Language: English
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  • 24
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Plant physiology. ; Biotic communities. ; Population biology. ; Plant ecology. ; Freshwater and Marine Ecology. ; Plant Physiology. ; Community and Population Ecology. ; Plant Ecology.
    Description / Table of Contents: Antarctic Seaweeds: Biogeography, Adaptation and Ecosystem Services -- Diversity of Antarctic Seaweeds -- Biogeographic Processes Influencing Antarctic and Sub-Antarctic Seaweeds -- Detached Seaweeds as Important Dispersal Agents Across the Southern Ocean.-Biogeography of Antarctic Seaweeds Facing Climate Changes -- Comparative Phylogeography of Antarctic Seaweeds: Genetic Consequences of Historical Climatic Variations -- Underwater Light Environment of Antarctic Seaweeds -- Production and Biomass of Seaweeds in Newly Ice-Free Areas: Implications for Coastal Processes in a Changing Antarctic Environment -- Carbon Balance Under a Changing Light Environment -- Life History Strategies, Photosynthesis and Stress Tolerance in Propagules of Antarctic Seaweeds -- Form and Function in Antarctic Seaweeds: Photobiological Adaptations, Zonation Patterns and Ecosystem Feedbacks -- Successional Processes in Antarctic Benthic Algae -- Seaweed-Herbivore Interactions: Grazing as Biotic Filtering in Intertidal Antarctic Ecosystems -- Diversity and Functioning of Antarctic Seaweed Microbiomes -- Seaweeds in the Antarctic Marine Coastal Food Web -- Trophic Networks and Ecosystem Functioning -- Chemical Mediation of Antarctic Macroalgal-Grazer Interactions -- Brown Algal Phlorotannins: An Overview of their Functional Roles.
    Abstract: Seaweeds (macroalgae) represent the most striking living components in the Antarctic’s near-shore ecosystems, especially across the West Antarctic Peninsula and adjacent islands. Due to their abundance, their central roles as primary producers and foundation organisms, and as sources of diverse metabolically active products, seaweed assemblages are fundamental to biogeochemical cycles in Antarctic coastal systems. In recent years, the imminence of climate change and the direct impacts of human beings, which are affecting vast regions of the Antarctic, have highlighted the importance of seaweed processes in connection with biodiversity, adaptation and interactions in the benthic network. Various research groups have been actively involved in the investigation of these topics. Many of these research efforts have a long tradition, while some “newcomers” have also recently contributed important new approaches to the study of these organisms, benefiting polar science as a whole. This book provides an overview of recent advances and insights gleaned over the past several years. Focusing on a timely topic and extremely valuable resource, it assesses the challenges and outlines future directions in the study of Antarctic seaweeds.
    Type of Medium: Online Resource
    Pages: XIV, 397 p. 68 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030394486
    DDC: 577.6
    Language: English
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  • 25
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cytology. ; Pharmacy. ; Biomedical Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cell Biology. ; Pharmacy.
    Description / Table of Contents: Chapter 1. Literature review -- Chapter 2. Results of experimental studies of short peptides (cytogens) in ophthalmology -- Chapter 3. Results of the clinical study of short peptides (cytogens) in ophthalmology -- Conclusion.
    Abstract: This book discusses the pathology of the retina, and reviews current research on the use of cell replacement therapy and short peptides to restore functional activity in retinal neurons. As the book describes, pathologies of the retina, including age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, present a long-standing challenge in the practice of clinical ophthalmology. Modern treatment for these conditions, which lead to irreversible blindness, includes laser exposure, surgical intervention, and drugs. These treatments aim to reduce the risk of new complications in the eye; pathogenetic therapy of degenerative diseases of the retina is practically absent in current ophthalmic practice. The first section of the book reviews the molecular mechanisms of age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, and reports on methods of treatment. The second section presents the results of recent experimental studies of the effects of short peptides on pluripotent embryonic cells; on proliferative activity in retinal cells and pigment epithelium; on expression of markers of differentiation or retinal neurons and pigment epithelium; and on the course of hereditary retinal pigmentation in Campbell rats. The third section offers results of clinical studies on the effectiveness of short peptides in patients with macular degeneration, and in patients with retinitis pigmentosa. The author concludes that the regular use of peptides in the treatment of degenerative diseases of the retina can slow the progression of the pathological process and preserve the patient’s vision for some 10-15 years. In addition, in 80 percent of patients, it is possible to increase visual function by increasing visual acuity, improving the boundaries of the visual field and the fundus.
    Type of Medium: Online Resource
    Pages: VI, 90 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030501600
    DDC: 610.72
    Language: English
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  • 26
    Keywords: Biotechnology. ; Microbiology. ; Plant diseases. ; Microbial ecology. ; Biotechnology. ; Microbiology. ; Plant Pathology. ; Microbial Ecology.
    Description / Table of Contents: Bacterial Endophytes: Diversity, Functional Importance, and Potential for Manipulation -- Rhizosphere Carbon Turnover from Cradle to Grave: The Role of Microbe–Plant Interactions -- Root–Soil–Microbe Interactions Mediating Nutrient Fluxes in the Rhizosphere -- Diazotrophic Nitrogen Fixation in the Rhizosphere and Endosphere -- Root Microbiome Structure and Microbial Succession in the Rhizosphere -- Rhizosphere Legacy: Plant Root Interactions with the Soil and Its Biome -- Rhizosphere Microbiome and Soil-Borne Diseases -- Root Disease Impacts on Root-Rhizosphere Microbial Communities -- Newly Introduced or Modified Genes in Plants Potentially Modulate the Host Microbiome -- Rhizosphere Plant–Microbe Interactions Under Abiotic Stress -- Arbuscular Mycorrhizal Fungi Interactions in the Rhizosphere -- Microbial–Faunal Interactions in the Rhizosphere -- Inter-Organismal Signaling in the Rhizosphere -- Molecular Mechanisms of Plant–Microbe Interactions in the Rhizosphere as Targets for Improving Plant Productivity -- Inoculation Effects in the Rhizosphere: Diversity and Function.
    Abstract: This book presents a detailed discussion on the direct interactions of plants and microorganisms in the rhizosphere environment. It includes fifteen chapters, each focusing on a specific component of plant-microbe interactions, such as the influence of plants on the root microbiome, and the downstream effects of rhizosphere microbial dynamics on carbon and nutrient fluxes in the surroundings. As such, the book helps readers gain a better understanding of diversity above the ground, and its effect on the microbiome and its functionality.
    Type of Medium: Online Resource
    Pages: XVIII, 356 p. 36 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811561252
    Series Statement: Rhizosphere Biology,
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Medical sciences. ; Pharmacology. ; Biomedical Research. ; Cell Biology. ; Health Sciences. ; Pharmacology.
    Description / Table of Contents: Autophagy and Alzheimer’s Disease -- Autophagy and Parkinson’s Disease -- Autophagy and Motor Neuron Diseases -- Autophagy and Prion Disease -- Autophagy and Lysosome Storage Disorders -- Autophagy and Mitochondrial Encephalomyopathies -- Autophagy and Ischemic Stroke -- Autophagy and Hemorrhagic Stroke -- Autophagy and Polyglutamine Disease -- Autophagy and Epilepsy -- Autophagy in Neurodevelopmental Disorders -- Autophagy and Pituitary Adenoma -- Autophagy in Schizophrenia -- Autophagy and Hypertension -- Autophagy and Myocardial Ischemia -- Autophagy and Heart Failure -- Autophagy, Myocarditis and Cardiomyopathy -- Autophagy, Hyperlipidemia and Atherosclerosis -- Application of Autophagy in Cardiovascular Diseases -- Autophagy and Tumorigenesis -- Autophagy and Tumour Stem Cells -- Autophagy and Tumour Metastasis -- Autophagy and Tumor Cell Death -- Autophagy and Tumour Chemotherapy -- Autophagy and Tumour Radiotherapy -- Autophagy and Inflammatory Diseases -- Autophagy and Immune-related Diseases -- Autophagy and Autoimmune Diseases -- Autophagy and Bacterial Infection -- Autophagy and Viral Infection -- Autophagy and Thyroid Disease -- Autophagy and Obesity and Diabetes -- Autophagy and Obesity-related Reproductive Dysfunction -- Autophagy and Acute Kidney Injury -- Autophagy and Glomerular Diseases -- Autophagy and Diabetic Nephropathy -- Autophagy and Liver Diseases -- Autophagy and Gastrointestinal Diseases -- Chronic Obstructive Pulmonary Disease and Autophagy -- Autophagy and Pulmonary Fibrosis -- Asthma and Autophagy -- Autophagy and Other respiratory diseases -- Autophagy and Leukemia -- Autophagy and Lymphoma -- Autophagy and Myeloma -- The Function and Mechanisms of Autophagy in Traumatic Brain Injury -- The Function and Mechanisms of Autophagy in Spinal Cord Injury -- The Function and Mechanisms of Autophagy in Trauma of Other Parts of the Body -- The Prospects of Therapeutic Potential and Drug Development Targeting Autophagy in Cancer -- Progress of Anti-aging Drugs Targeting Autophagy -- Drug Development and Treatment of Autophagy in Other Diseases -- Systems Biology Approaches in Autophagy Research -- Natural Product Regulates Autophagy in Cancer -- Regulation of Autophagy in Neurodegenerative Diseases by Natural Products -- Regulation of Autophagy in Cardiovascular Diseases by Natural Products.
    Abstract: This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine.
    Type of Medium: Online Resource
    Pages: XXXVI, 736 p. 50 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811542725
    Series Statement: Advances in Experimental Medicine and Biology, 1207
    DDC: 610.72
    Language: English
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  • 28
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Entrepreneurship. ; New business enterprises. ; Public health. ; Biotechnology. ; Biomedical Research. ; Entrepreneurship. ; Public Health.
    Description / Table of Contents: Part I. What Is Wrong with Health? What Should the Future of Health Be? -- INNOVATION DESIGN for the FUTURE of HEALTH -- Health Innovations from an Innovators’ Perspective -- From SICKCARE to HEALTHCARE to HEALTH -- Future Look on Health: Opportunities -- Navigating Towards a Future of “One Health” -- Part II. Exponential Medicine + Technologies + Mindset -- Exponential Technologies for an Exponential Medicine -- Exponential Medicine: Challenges of Human Spaceflight Bringing Innovations for Earth—A Case Study -- Healthy Longevity -- The Science of Health Longevity -- Space Healthtech: Innovation Base for Longevity -- Part III. Future Health Value Propositions -- Healthcare the Melting Pot of Technology, Humanity, and Confusion -- Democratize Health Delivery -- Health Innovation Process: Definitions and Short Methodology Introductions -- Prevention, Prediction, Personalization, and Participation as Key Components in Future Health -- Digital Health Business Models: Transformation Is on the Horizon -- Value Propositions for Future Health Developments: Digital, Portable, Connected, Experience-Enhancing, Supportive, Patient-Centric, and Affordable -- (Digital) Patient Journey and Empowerment: Digital Twin -- Part IV. Innovation Methodology Basics -- Stanford Biodesign as Base: Empathy and Patient Centricity as the Main Driver -- Purpose Launchpad Methodology: Introduction -- Design Thinking for Innovations in Healthcare -- VPC to BMC to Exponential Canvas: Canvas Interconnectivity for Exponential Scaling -- Innovation Methodology I3 EME: Awareness for Biomedical Engineers -- Part V. Ethics + Health Innovation -- Integrating Ethical Considerations into Innovation Design -- Part VI. Health Innovation Design -- Case Studies Used Throughout the Book: Innovation Categories Explained -- Why Is Healthcare Different with Respect to Innovation and Entrepreneurial Activities? -- Purpose Launchpad Health (PLH) Methodology Introduction -- Part VII. Purpose Launchpad Health -- Purpose Launchpad Health: Exploration and Evaluation Phases—Actual Case Studies -- Part VIII. Health Leadership, Skills and other Methodologies -- Soft Skills Needed for Problem Understanding and Innovation Generation -- Leadership in Healthcare: A Novel Approach. Healthcare Executives’ Traits, Styles, and Approaches -- Future Skills Framework in Healthcare -- Porter’s Five Forces Analysis: Quo Vadis Immunotherapy Industry -- Part IX. Health Entrepreneurship -- Global Health Markets and Their Different Needs -- Patient: Health Relation and Digital Health Entrepreneurship -- Health Start-Up: Create Impact and be Investment Ready Intra- and Entre-Preneurs -- Regulatory Issues for Health Innovations -- Innovation Think Tank Frameworks for Resolving “The Innovator’s Dilemma” in Healthcare -- A Primer on Patents and IP for Health Innovations -- Successfully Implementing Ambidexterity in the Medical Industry -- Reverse Innovation: Circumvent Digital Health Transformation Issues -- Part X. Health Innovation Education and Incubation -- Health Innovation Design: “CAMPing” for the Unmet Clinical Need -- Health Technology Innovation Generation (HTIG) Lecture and Project Classes at AGH University -- Health Innovation Design at a University: INKA INNOLAB at Otto-von-Guericke-University -- Clinical Innovation at Acibadem Biodesign Center -- Example of a Needs-Driven Innovation Training Program: The BioMedical Design Novo Nordisk Foundation Fellowship Program -- Addressing the Healthcare Needs with Innovation Think Tank Global Infrastructure and its Methodology -- The Power of a Collaborative Ecosystem: Introducing the Edison™ Accelerator -- HealthTec Networks and Clusters (Global): Innovation Clusters in Medtech in Europe -- Leadership-Compass: “Networking and Synapting Empowered by Health Captains” -- Part XI. Purpose Launchpad Health: Toolset Templates and Principles -- PLH Templates and Principles.
    Abstract: This book highlights the reasons for an urgently needed revision of the current global healthcare setup, discusses the needed mindset for a future of health, and provides a comprehensive development toolset for disruption (and for the needed incremental innovations towards disruption). Today’s biomedical and health innovation related research in universities encourages activities that lead to incremental innovations with a relatively low risk of failure. The healthcare industry on the other hand provides tools and devices for established healthcare providers to improve the diagnosis and therapy/ treatment of the patients’ health problems. The patient is not in the center of healthcare provision however, and prevention and prediction are not core goals. The current health setup needs to be challenged and disrupted. Disruptions are coming from technologies or processes that lead to a significant (〉10x) reduction in cost or price/ performance and that also come with new business models. The need for change, effects of exponential technologies, and the needed shift to prevention and to homecare for health democratization and patient empowerment will be discussed in detail in the first parts of the book. The subsequent sections address several innovation methods with a focus on a novel meta methodology named Purpose Launchpad Health. This is followed by a comprehensive discussion on health entrepreneurship activities and needs. The final section of the book addresses how to train students to become entrepreneurial health innovators, presenting successful curricula and examples of health incubation and accelerator setups. All of the innovation tools presented and used in this book are summarized in the final chapter to help the reader get started planning an entrepreneurial venture. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments. Chapters are concise and enriched with key messages, learning objectives and real innovation examples to bridge theory and practice. This book aims to serve as a teaching base for health innovation design and to prepare for health-related entrepreneurial ventures. Readers with medical, biomedical, biotechnology, and health economics backgrounds - and anyone who wants to become a future oriented health innovator or who believes in disruptive approaches - will find this book a useful resource and teaching tool for developing validated products/ services and processes for the future of health.
    Type of Medium: Online Resource
    Pages: XXXIV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031081910
    DDC: 660.6
    Language: English
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  • 29
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medicine Philosophy. ; Medical sciences. ; Science Philosophy. ; Biomedical Research. ; Philosophy of Medicine. ; Health Sciences. ; Philosophy of Science.
    Abstract: This edited volume aims to better understand the multifaceted phenomenon we call health. Going beyond simple views of health as the absence of disease or as complete well-being, this book unites scientists and philosophers. The contributions clarify the links between health and adaptation, robustness, resilience, or dynamic homeostasis, and discuss how to achieve health and healthy aging through practices such as hormesis. The book is divided into three parts and a conclusion: the first part explains health from within specific disciplines, the second part explores health from the perspective of a bodily part, system, function, or even the environment in which organisms live, and the final part looks at more clinical or practical perspectives. It thereby gathers, across 30 chapters, diverse perspectives from the broad fields of evolutionary and systems biology, immunology, and biogerontology, more specific areas such as odontology, cardiology, neurology, and public health, as well as philosophical reflections on mental health, sexuality, authenticity and medical theories. The overarching aim is to inform, inspire and encourage intellectuals from various disciplines to assess whether explanations in these disparate fields and across biological levels can be sufficiently systematized and unified to clarify the complexity of health. It will be particularly useful for medical graduates, philosophy graduates and research professionals in the life sciences and general medicine, as well as for upper-level graduate philosophy of science students.
    Type of Medium: Online Resource
    Pages: XVII, 555 p. 30 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030526634
    Series Statement: Healthy Ageing and Longevity, 12
    DDC: 610.72
    Language: English
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  • 30
    Keywords: Biotechnology. ; Food science. ; Biomaterials. ; Nanotechnology. ; Ceramic materials. ; Biotechnology. ; Food Science. ; Biomaterials. ; Nanotechnology. ; Ceramics.
    Description / Table of Contents: Carbon materials from various sources for composite materials -- Carbon Fibre Reinforced Polymer (CFRP) Composites: Machining Aspects and Opportunities for Manufacturing Industries -- Surface modification of graphene nanoplatelets (GNP) towards preparation of natural/synthetic rubber blend nanocomposites -- Mechanical properties of nanoclay composite materials -- Fireproof capability of rigid polyurethane foam based composite materials -- Structural behavior of composite materials in fire -- Natural resources based green composite materials -- Composite materials for wind turbine structure -- Electrochromic Smart Windows: An Energy-efficient Technology -- Graphitic Carbon Nitride/ Metal Oxides Nanocomposites and Their Applications in Engineering -- Application of Nanofiber-based Composites: Progressive Health Impact -- Polymer-based Nanocomposite: Recent Trends in Safety Assessments in biomedical applications -- Modern approach of hydroxyapatite based composites for biomedical applications -- Hybrid Composite in Orthopedic applications -- Polymer-based composite in biomedical applications -- Components of All-solid-state Ion-Selective Electrodes (AS-ISEs) -- Nanocellulose and Nanocellulose-based Composites for Food Applications -- Nanocomposite Materials in Food Packaging: Opportunities, Challenges and Safety Assessment -- Biodegradability and Composite Coatings: Past, Present and Future Prospects -- Nanocomposite Film for Food Packaging: Opening Doors to Future Applications -- Functional Chitosan-Based Composites for Potential Application in Food Industry -- Metal-insulator-metal as a biosensing platfrom .
    Abstract: Composite materials are formed when the combination of separate materials acquire new properties distinct from its components. They have a range of applications in fields such as mechanical and electrical engineering, food science and biomedicine and represent a fast-growing area of research. Composite Materials: Applications in Engineering, Biomedicine and Food Science provides an overview of current technologies and applications related to composite materials in these fields. Organized by discipline, the text encompasses a wide variety of composite materials, including polymer, ceramic, biomaterial, hydroxyapatite, nanofiber and green composites. Early chapters detail the enhanced mechanical, magnetic, dielectric properties of electrical and thermal conductive composite materials, which are essential in daily science. Subsequent chapters focus on filler or reinforcement materials, including carbon materials, hybrid materials and nanomaterials. Particular emphasis is placed on nanocomposite materials, as these have increasingly diverse field applications. Various manufacturing methods, such as the synthesis method and top-down/bottom-up manufacturing, are also discussed. Coverage of the recent progress, challenges and opportunities surrounding composite materials make this text a one-stop reference for engineers, scientists and researchers working in this exciting field.
    Type of Medium: Online Resource
    Pages: XI, 484 p. 213 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454890
    DDC: 660.6
    Language: English
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  • 31
    Keywords: Biotechnology. ; Agriculture. ; Botany. ; Microbiology. ; Biology Technique. ; Biotechnology. ; Agriculture. ; Plant Science. ; Microbiology. ; Biological Techniques.
    Description / Table of Contents: 1.An Introduction to Beta Glucan and Beta Glucanases -- 2.Industrial Applications of Beta Glucanases -- 3.Microbial Sources of Beta Glucanase Enzymes -- 4.Role of Beta Glucanases in Animal Nutrition -- 5.Betaglucanse in Breweries -- 6. Exploitation of Actinobacteria for Beta Glucanolytic enzymes –Screening and Characterisation -- 7.Structural Characterisation of Beta Glucanase Genes from Actinobacteria -- 8.Application of Codon Optimization in Actinobacterial Beta Glucanases -- 9.Actinobacterial Beta Glucanases: Recombinant Expression of in E. coli -- 10.Purification and Properties of Recombinant Beta Glucanases Enzymes -- 11.Fungal Beta Glucanases -- 12.Industrial Production and Characterisation of Beta Glucanases -- 13.Protein Engineering of Beta Glucanase Enzymes -- 14.Biotechnological Avenues in Hybrid Beta Glucanase Enzyme Production.
    Abstract: This book offers an overview of the current knowledge on beta glucanase enzymes derived from actinobacterial source, their structure, functions and industrial applications. It summarizes the exploitation of actinomycetes, assay methods for beta glucanase screening, structural characterisation, genetic engineering, protein engineering, strategies for purification, characterisation and finally how to synthesize a hybrid enzyme of beta glucanases.Enzyme beta glucanases have considerable interest in industrial biotechnology owing to its distinct effect on the hydrolysis of insoluble beta glucan molecules and applications in particular industrial sectors such as food, feed and beverages industries. The beta glucanases are characterized extensively in microorganisms viz. bacteria, fungi and also in plants. A wide varieties of actinobacterial β- glucanases have exclusively active on β-glucan substrates and cleave the mixed linkage β-glucan chains at different points. This is significant for picking precise substrates for the assay of each type of enzymes within this enzyme groups. The well recognized specificity and mechanism of action within the enormous substrates allow to understand that most of them are varied from cellulases, excluding β-1,4-glucanases. The progress in genetic and protein engineering in actinobacterial beta glucanases improves the stability, activity and thermodynamic properties in relation with industrial relevance. This book will be useful for researchers and students engaged in industrial biotechnology, enzyme production, molecular biology, protein engineering and many more.
    Type of Medium: Online Resource
    Pages: X, 195 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811964664
    Series Statement: Interdisciplinary Biotechnological Advances,
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Metabolism Disorders. ; Genetics. ; Cardiovascular system. ; Physiology. ; Biomedical Research. ; Metabolic Disease. ; Genetics and Genomics. ; Cardiovascular Physiology.
    Description / Table of Contents: An overview of genome editing in cardiovascular and metabolic diseases -- Bioinformatics research methodology of genome editing in cardiovascular and metabolic diseases -- Online databases of genome editing in cardiovascular and metabolic diseases -- Application of systems biology for genome editing involved in regulating of cardiovascular and metabolic diseases -- Bioinformatics for reducing off-targets in cardiovascular and metabolic diseases -- Genome editing and cardiac regeneration -- Genome editing and myocardial development -- Genome editing and heart failure -- Genome editing and pathological cardiac hypertrophy -- Genome editing and cardiac remodeling -- Genome editing and diabetic cardiomyopathy -- Genome editing and cardiac arrhythmias -- Genome editing and atrial fibrillation -- Genome editing and muscle atrophy -- Genome editing and obesity -- Genome editing and fatty liver -- Genome editing and diabetes -- Genome editing and gout -- Genome editing and protein energy malnutrition -- Genome therapy and cardiovascular diseases -- Therapeutics in metabolic diseases -- Gene editing and human iPSCs in cardiovascular and editing diseases -- Prospective advances in genome editing investigation.
    Abstract: This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.
    Type of Medium: Online Resource
    Pages: XII, 339 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811956423
    Series Statement: Advances in Experimental Medicine and Biology, 1396
    DDC: 610.72
    Language: English
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    Keywords: Freshwater ecology. ; Marine ecology. ; Reproduction. ; Physiology. ; Pollution. ; Freshwater and Marine Ecology. ; Reproductive Physiology. ; Pollution.
    Description / Table of Contents: 1. Pesticide and xenobiotic metabolism in aquatic organisms -- 2. Endocrine disrupting activity of xenobiotics in aquatic animals -- 3. Water contamination through xenobiotics and their toxic effects on aquatic animals -- 4. Cypermethrin induced reproductive toxicity in zebrafish: biochemical and molecular perspective -- 5. Impact of Pesticides Application on Aquatic Environments And Biodiversity -- 6. Impact of microplastics on reproductive and physiological aspects of aquatic inhabitants -- 7. The Impact of Xenobiotics in Development & Reproduction of fresh water Fishes -- 8. Mixtures and Reproduction in Aquatic Organisms – benefits and challenges -- 9. Phytoestrogens as Endocrine-Disrupting Agents In Aquaculture -- 10. A Proteomic Approach to Studying the Effects of Xenobiotics on Aquatic Living Organisms -- 11. Role of Cytochrome P450 in xenobiotic metabolism in fishes -- 12. Pharmacokinetic-Pharmacodynamic modelling of Xenobiotics: Fate and effect in Aquatic Animals -- 13. Occurrence of xenoestrogen alkylphenols (Octylphenols and Nonylphenol), and its impact on the aquatic ecosystem -- 14. Xenobiotics' effect on fish reproduction and development -- 15. Scientometric analysis of ecotoxicological investigations of xenobiotics in aquatic animals -- 16. Toxic effects of nanomaterials on aquatic animals and their future prospective -- 17. Microplastic Contamination in Aquatic organisms: An Ecotoxicological perspective -- 18. Effect of xenobiotics and their degradation in aquatic life -- 19. Transcriptome analysis of aquatic species exposed to endocrine disruptors -- 20. Fundamentals of genotoxicity and antiparasitic drugs associated with genotoxicity in fish -- 21. Endocrine disrupting compounds (EDCs) as emerging aquatic contaminants: Emphasis on Reproduction and Development.
    Abstract: This book summarizes the latest understanding of the impact of xenobiotics on the developmental and reproductive processes of aquatic animals, particularly nektonic forms, which comprise an important group of aquatic ecosystems. Aquaculture is quickly becoming the largest contributor of fish protein for human consumption. As the aquaculture business expands, farmed fish will be exposed to more environmental toxins, necessitating the use of chemical therapeutic drugs for fish. This book brings together experts on the regulation of environmental toxins and food chemicals from around the world, as well as researchers looking into the metabolism and disposal of foreign chemicals (xenobiotics) in fish species. The impact of xenobiotics on reproductive and developmental biology of all living forms has become of prime importance at the current time. As the effect of these xenobiotics on aquatic animals is an emerging area for research and development, several groups across the world are working on these aspects, targeting different groups of fishes in both marine and freshwater ecosystems. This collective work highlights several key and updated recent aspects of different types of xenobiotics entering aquatic ecosystems, impacts of these agents on reproductive physiology, developmental biology, breeding biology, hormonal imbalance, aquatic ecology, and pollution on the aquatic ecosystem. The unique aggregation of different types of stressors to aquatic animals under a single volume will be a useful reference for readers, including scientists, teachers, students, researchers and policymakers and those involved in aquaculture and environment conservation.
    Type of Medium: Online Resource
    Pages: XXIX, 427 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819912148
    DDC: 577.6
    Language: English
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  • 34
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomaterials. ; Mathematical models. ; Dentistry. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Mathematical Modeling and Industrial Mathematics. ; Dentistry. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1 - Systematic Errors in Longitudinal Measurements -- Chapter 2 - Endodontic Treatment and Vertical Root Fracture -- Chapter 3 - Debonding of Resin Composite Restorations -- Chapter 4 - Attenuation of Curing Light through Resin Composite Restorations -- Chapter 5 - Release of Ions or Molecules from Dental Restorations -- Chapter 6 - Heat Generated from Dental Resin Composites during Curing -- Chapter 7 - Mechanical Failure of Dental Restorations – The Weakest-Link Theory -- Chapter 8 - Stability of Dental Implants -- Chapter 9 - Kinetics of Photo-polymerization -- Index.
    Abstract: This book presents a mechanistic approach—mathematical modeling—for carrying out dental materials research. This approach allows researchers to go beyond the null hypothesis and obtain a solution that is more general and therefore predictive for conditions other than those considered in a study. Hence it can be used either on its own or to complement the commonly used statistical approach. Through a series of practical problems with wide-ranging application, the reader will be guided on: How to construct a mathematical model for the behavior of dental materials by making informed assumptions of the physical, chemical, or mechanical situation How to simplify the model by making suitable simplifications How to calibrate the model by calculating the values of key parameters using experimental results How to refine the model when there are discrepancies between predictions and experiments Only elementary calculus is required to follow the examples and all the problems can be solved by using MS Excel© spreadsheets. This is an ideal book for dental materials researchers without a strong mathematical background who are interested in applying a more mechanistic approach to their research to give deeper insight into the problem at hand. Advance praise for Mathematical Models for Dental Materials Research: “This is a nice addition for research students on how to conduct their work and how to manage data analysis. It brings together a number of important aspects of dental materials investigations which has been missing in the literature. The practical examples make it much easier to understand.” – Michael F. Burrow, Clinical Professor in Prosthodontics, The University of Hong Kong “The great strengths of this volume are the real world examples of dental materials research in the successive chapters. In turn, this is an outcome of the outstanding expertise of both authors. I warmly recommend this book to the dental biomaterials community worldwide.” – David C. Watts, Professor of Biomaterials Science, University of Manchester, UK.
    Type of Medium: Online Resource
    Pages: XIV, 77 p. 41 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378493
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Environment. ; Renewable energy sources. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Biotechnology. ; Environmental Sciences. ; Renewable Energy. ; Fossil Fuel.
    Description / Table of Contents: Chapter 1. Growth of Biofuels Sector: Opportunities, Challenges and Outlook -- Chapter 2. Bioconversion of Agro-Industrial Residues to Second-Generation Bioethanol -- Chapter 3. Catalytic Transformation of Ethanol to Industrially Relevant Fine Chemicals -- Chapter 4. Selective Bioethanol Conversion to Chemicals and Fuels via Advanced Catalytic Approaches -- Chapter 5. A Spotlight on Butanol and Propanol as Next-Generation Synthetic Fuels -- Chapter 6. Technological Advancements in the Production and Application of Biomethanol -- Chapter 7. Biorefinery Approaches for Production of Fuels and Chemicals from Lignocellulosic and Algal Feedstocks -- Chapter 8. Conversion of Rice Husk and Nutshells into Gaseous, Liquid and Solid Biofuels -- Chapter 9. A Review of Thermochemical and Biochemical Conversion of Miscanthus to Biofuels -- Chapter 10. Process Improvements and Techno-Economic Feasibility of Hydrothermal Liquefaction and Pyrolysis of Biomass for Bio-Crude Oil Production -- Chapter 11. Biocrude Oil Production via Hydrothermal Liquefaction of Algae and Upgradation Techniques to Liquid Transportation Fuels -- Chapter 12. Co-pyrolysis of Lignocellulosic Biomass and Polymeric Wastes for Liquid Oil Production -- Chapter 13. Conversion of Waste Biomass to Bio-oils and Upgradation by Hydrothermal Liquefaction, Gasification and Hydrodeoxygenation -- Chapter 14. Upgrading of Bio-oil from Biomass Pyrolysis: Current Status and Future Development -- Chapter 15. Heterogeneous catalysis in Hydroxymethylfurfural Conversion to Fuels and Chemicals -- Chapter 16. Conversion of Glycerol to Value-added Products -- Chapter 17. Recent Advances in Steam Reforming of Glycerol for Syngas Production -- Chapter 18. Conversion of Biogas to Syngas via Catalytic Carbon Dioxide Reforming Reaction: An Overview of Thermodynamic Aspects, Catalytic Design and Reaction Kinetics -- Chapter 19. Opportunities of Biodiesel Compatibility as a Modern Combustion Engine Fuel -- Chapter 20. Current Advancements in Microbial Fuel Cell Technologies.
    Abstract: This book summarizes recent advances in the processing of waste biomass resources to produce biofuels and biochemicals. Worldwide interest in clean energy sources, environmental protection, and mitigating global warming is rapidly gaining momentum and spurring on the search for alternative energy sources, especially for the transportation and industrial sectors. This book reviews the opportunities presented by low-cost organic waste materials, discussing their suitability for alternative fuel and fine chemical production, physicochemical characterization, conversion technologies, feedstock and fuel chemistry, refining technologies, fuel upgrading, residue management, and the circular economy. In addition, it explores applied aspects of biomass conversion by highlighting several significant thermochemical, hydrothermal and biological technologies. In summary, the book offers comprehensive and representative descriptions of key fuel processing technologies, energy conversion and management, waste valorization, eco-friendly waste remediation, biomass supply chain, lifecycle assessment, techno-economic analysis and the circular bioeconomy.
    Type of Medium: Online Resource
    Pages: XVIII, 494 p. 111 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811518041
    DDC: 660.6
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Biochemistry. ; Psychology. ; Dentistry. ; Endocrinology. ; Biomedical Research. ; Medical Biochemistry. ; Biochemistry. ; Behavioral Sciences and Psychology. ; Dentistry. ; Endocrinology.
    Description / Table of Contents: Part 1: What is Salivary Bioscience, Why is it Important, and How Do We Study It? -- Chapter 1: Foundations of Interdisciplinary Salivary Bioscience: An Introduction (Granger et al.) -- Chapter 2: Salivary Gland Anatomy and Physiology (Hernández et al.) -- Chapter 3: Saliva Collection, Handing, Transport, and Storage: Special Considerations and Best Practices for Interdisciplinary Salivary Bioscience(Padilla et al.) -- Chapter 4: Analytical Strategies and Tactics in Salivary Bioscience (Riis et al.) -- Part 2: Physiology and Development Research and Applications (Part 2 Editor: Dr. Jenna Riis) -- Chapter 5: Salivary Bioscience, Human Stress, and the Hypothalamic Pituitary Adrenal Axis (Clow et al.) -- Chapter 6: The Use of Saliva for Genetics and Epigenetics Research (Nemoda et al.) -- Chapter 7: Saliva as a Window Into the Human Oral Microbiome and Metabolome(Whiteson et al.) -- Chapter 8: Salivaomics, saliva Exo-somics, and Saliva Liquid Biopsy (Wong et al.) -- Chapter 9: Salivary Bioscience, Immunity, and Inflammation (Riis et al.) -- Chapter 10:Salivary Bioscience and Human Development (Hibel et al.) -- Part 3: Biomedical Research and Related Applications (Part 3 Editor: Dr. Elizabeth Thomas) -- Chapter 11: Biomedical Research and Related Applications:Current Assay Methods and Quality Requirements in Oral Fluid Diagnostics Applications (Granger S. et al.) -- Chapter 12: Salivary Biomarkers and Neurodegenerative Conditions (Thomas et al.) -- Chapter 13: The Use of Antibodies in Saliva to Measure PathogenExposure and Infection(Heaney et al.) -- Chapter 14: Salivary Bioscience and Pain (Payne et al.) -- Chapter 15: Salivary Bioscience and Environmental Exposure Assessment (Panuwet et al.) -- Chapter 16: Saliva and Drugs of Abuse (Navazesh et al.) -- Chapter 17: Therapeutic Drug Monitoring in Saliva (Thomas) -- Chapter 18: Salivary Bioscience and Periodontal Medicine (Freire et al.) -- Chapter 19: Salivary Bioscience and Cancer (Navazesh et al.) -- Part 4: Psychosocial Research and Applications(Part 4 Editor: Dr. Kate Ryan Kuhlman) -- Chapter 20: Salivary Bioscience in Clinical Psychologyand Psychiatry(Kuhlman) -- Chapter 21: Salivary Bioscience Research in Health Psychology and Behavioral Medicine (Hoyt et al.) -- chapter 22: The Neuroscience of Human Social Behavior: A Review of How Testosterone and Cortisol Underpin Competition and Affiliation Dynamics (Kornienko et al.) -- chapter 23: Salivary Studies of the Social Neuroscience of Human-animal Interaction (Pendry et al.) -- Part 5: Population Health Research and Applications(Part 5 Editor: Dr. Marcus Taylor) -- Chapter 24: Salivary Bioscience and Military, Space, and OperationalResearch(Roma et al.) -- Chapter 25: Salivary Bioscience Research Related to Prenatal Adversity (Eiden et al.) -- Chapter 26: Salivary Bioscience and Pediatrics (Johnson et al.) -- Chapter 27: Use of saliva to better understand the experience of adulthood and aging(Almeida et al.) -- Chapter 28: Salivary Bioscience and Research on Animal Welfare and Conservation Science(Staley et al.) -- Part 6: The Way Forward: Future Directions for the Science and Practice of Salivary Bioscience -- Chapter 29:Applications of Salivary Bioscience to Precision Medicine (Kuhlman) -- Chapter 30:Public Health and IndustryApplications of Salivary Bioscience (Riis et al.) -- Chapter 31: Envisioning the Future of Interdisciplinary Salivary Bioscience (Granger et al.).
    Abstract: This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice.
    Type of Medium: Online Resource
    Pages: XIV, 751 p. 56 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357849
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Parasitology. ; Biomedical Research. ; Medical Microbiology. ; Parasitology.
    Description / Table of Contents: Preface -- Chapter1. Advances in experimental research about periodontitis: lessons from the past, ideas for the future (Julien Santi-Rocca) -- Part I: Periodontal microbiota -- Chapter 2. Microbiota in Periodontitis: advances in the omic era (Shao Bing Fong, Emile Boyer, Martine Bonnaure-Mallet, Vincent Meuric) -- Chapter 3. Aggregatibacter actinomycetemcomitans: from basic to advanced research (Abdelhadi Hbibi, Amal Bouziane, Badiaa Lyoussi, Mimoun Zouhdi, Driss Benazza) -- Chapter 4. Meta-analyses on the Periodontal Archaeome (Jéssica Alves de Cena, Yuri Silvestre-Barbosa, Aline Belmok, Cristine Miron Stefani, Cynthia Maria Kyaw, Nailê Damé-Teixeira) -- Chapter 5. Parasites in periodontal health and disease: a systematic review and meta-analysis (David Felipe Martin-Garcia, Malik Sallam, Gabriela Garcia, Julien Santi-Rocca) -- Chapter 6. Fungi - a component of the oral microbiome involved in periodontal diseases (Justyna Karkowska-Kuleta, Dorota Satala, Magdalena Smolarz, Marcin Zawrotniak, Maria Rapala-Kozik) -- Chapter 7. Herpesviruses in periodontitis: An umbrella review (Aleksandar Jakovljevic, Miroslav Andric, Jelena Jacimovic, Jelena Milasin, Javier Enrique Botero) -- Part II: Periodontitis pathophysiology -- Chapter 8. Recent updates on microbial biofilms in periodontitis: an analysis of in vitro biofilm models (Maick Meneguzzo Prado, Nathalia Figueiredo, Andréa Pimenta, Tamires Szeremeske Miranda, Magda Feres, Luciene Cristina Figueiredo, Josiane de Almeida, Bruno Bueno-Silva) -- Chapter 9. Update on B cell response in periodontitis (Julien Demoersman, Jacques Olivier Pers) -- Chapter 10. Polarization profiles of T lymphocytes and macrophages responses in periodontitis (Franco Cavalla, Marcela Hernández) -- Chapter 11. Complementary experimental methods in genetics open up new avenues of research to elucidate the pathogenesis of periodontitis (Arne S. Schaefer) -- Part III: Periodontitis-associated conditions -- Chapter 12. Update on the bidirectional link between diabetes and periodontitis (Leila Salhi, Michèle Reners) -- Chapter 13. Periodontitis as a risk factor for Alzheimer’s disease: the experimental journey so far, with hope of therapy (Alice Harding, Shalini Kanagasingam, Richard Welbury, Sim K. Singhrao) -- Chapter 14. Cardiovascular diseases and periodontitis (Peter Riis Hansen, Palle Holmstrup) -- Part IV: Therapeutic management of periodontitis -- Chapter 15. Update on the role of cytokines as oral biomarkers in the diagnosis of periodontitis (Triana Blanco-Pintos, Alba Regueira-Iglesias, Carlos Balsa-Castro, Inmaculada Tomás) -- Chapter 16. Non-surgical periodontal treatment: SRP and innovative therapeutic approaches (Alexia Vinel, Antoine Al Halabi, Sébastien Roumi, Hélène Le Neindre, Pierre Millavet, Marion Simon, Constance Cuny, Jean-Sébastien Barthet, Pierre Barthet, Sara Laurencin-Dalicieux) -- Chapter 17. Update on the roles of oral hygiene and plaque control on periodontal disease (Leila Salhi, Bruno De Carvalho, Michèle Reners) -- Chapter 18. Multi-photonic adjunctive therapy for the management of periodontitis: recent advances and new treatment approach (Marco Giannelli, Daniele Bani) -- Chapter 19. Probiotics during the therapeutic management of periodontitis (Flavia Furlaneto, Karin Hitomi Ishikawa, Michel Reis Messora, Marcia P A Mayer) -- Chapter 20. Periodontal cell therapy: a systematic review and meta-analysis (Antoine Dubuc, Valérie Planat-Bénard, Mathieu Marty, Paul Monsarrat, Philippe Kémoun) -- Index.
    Abstract: Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendations for health professionals. A better information of the empowered patients, leading them to consider prevention and to take part in their therapeutic course. The book “Periodontitis: Advances in Experimental Research” includes a timely collection of chapters covering all the fields of research about periodontitis, consisting in concise reviews by the best specialists themselves and with clinical perspectives for periodontitis. Recent technological advances have allowed to explore shadowed areas of periodontology. The book “Periodontitis: Advances in Experimental Research” is a unique occasion to set a milestone for a more integrated field of periodontitis, with a broad scientific, medical, and public audience thanks to dedicated sections in each chapter: Abstract and main body (scientific audience and expert clinicians) Highlights (scientific audience and clinicians) Impact for Practice (clinicians and economical/political decision makers) Summary for Patients (patients and economical/political decision makers).
    Type of Medium: Online Resource
    Pages: XIII, 402 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968816
    Series Statement: Advances in Experimental Medicine and Biology, 1373
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Cancer. ; Technology Sociological aspects. ; Genomics. ; Biomedical Research. ; Cancer Biology. ; Emerging Technologies. ; Genomics.
    Description / Table of Contents: Chapter 1. Introduction to emerging technologies in biomedical sciences -- Chapter 2. Bioprospecting : boon or curse -- Chapter 3. Growing need for interdisciplinary biomedical research -- Chapter 4. Interplay between theory and experiment : a future approach for biomedical research -- Chapter 5.past, present and future perspectives of biomedical innovation in india -- Chapter 6. Systems biology approaches to study disease comorbidities -- Chapter 7. Bioinformatics the interactome of multidisciplinary approaches -- Chapter 8. Role of artificial intelligence in diagnosis of infectious diseases -- Chapter 9. Dna digital data storage breakthroughs in biomedical research. Chapter 10. Biomedical applications cloud-based iot -- Chapter 11. Next generation sequencing in cancer research -- Chapter 12. Crispr: genome editing and beyond -- Chapter 13. Omics in tuberculosis diagnosis : today and tomorrow -- Chapter 14. Advances in proteomic approaches for chronic kidney disease -- Chapter 15. 3 d bioprinting of tissues and organs : a new paradigm in regenerative medicine and biomedical engineering -- Chapter 16. Virtual planning, rapid prototyping and 3-d printing in orthopedic surgery -- Chapter 17. Tissue chips: contemporary applications and advancementstissue chips: contemporary applications and advancements -- Chapter 18. Flow cytometry for measuring neutrophil function -- Chapter 19. Flow cytometer for understanding genome size variation among medicinal herbs and non-edible oil trees of northeast india -- Chapter 20. Raman spectroscopy applications for bacterial detection -- Chapter 21. Microfluidic point-of-care diagnostic devices: a contemporary relevance. Chapter 22. Fluorescent dots for breast cancer management -- Chapter 23. Molecular mimicry : unravelling the role of autoantibodies in autoimmune diseases and infertility -- Chapter 24. Strategies of vaccine development -- Chapter 25. Preclinical models of intimal hyperplasia and restenosis to predict clinical events and develop novel therapies -- Chapter 26. Sphingolipids : a roadmap from biomarker identification to clinical application -- Chapter 27. Future of gastrointestinal endoscopy -- Chapter 28. Beating heart in a box : the future of cardiac transplant -- Chapter 29. The journey of coronary stent technology -- Chapter 30. Materiovigilance in clinical surgery.
    Abstract: This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.
    Type of Medium: Online Resource
    Pages: XIII, 505 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643453
    DDC: 610.72
    Language: English
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  • 39
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Microbial genetics. ; Industrial microbiology. ; Microbiology. ; Biomedical Research. ; Medical Microbiology. ; Microbial Genetics. ; Industrial Microbiology. ; Microbiology.
    Description / Table of Contents: Chapter 1. Epidemiology of Oral Squamous Cell Carcinoma in Indian Scenario -- Chapter 2. Risk factors for Oral Squamous Cell Carcinoma in the Indian population -- Chapter 3. Molecular Carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 4. Inflammation and Infection in Cancer -- Chapter 5. Role of Inflammation and Infection in Oral Squamous Cell Carcinoma -- Chapter 6. Normal Microbiome of Oral cavity -- Chapter 7. Oral Microbiome in Oral Squamous Cell Carcinoma -- Chapter 8. Microbial Dysbiosis in Oral Squamous Cell Carcinoma -- Chapter 9. Bacteria induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 10. Virus induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 11. Fungi: Culprits or Bystanders in Oral Squamous Cell Carcinoma -- Chapter 12. Microbial ‘omics’ in Oral Squamous Cell Carcinoma -- Chapter 13. Implications and Future perspectives.
    Abstract: This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention. The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like for this area of research. The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.
    Type of Medium: Online Resource
    Pages: XIII, 172 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811905926
    DDC: 610.72
    Language: English
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  • 40
    Keywords: Medicine Research. ; Biology Research. ; Medical education. ; Anatomy. ; Virtual reality. ; Augmented reality. ; Biomedical Research. ; Medical Education. ; Anatomy. ; Virtual and Augmented Reality.
    Description / Table of Contents: Chapter 1. Pandemic-Era Digital Education: Insights from an Undergraduate Medical Programme -- Chapter 2. Use of Lt Systems in Large Class Lab Delivery -- Chapter 3. COVID-19 Adaptations for Biomedical Teaching and Assessment Within the Undergraduate Dental Curriculum -- Chapter 4. One Size Does Not Fit All in Remote Anatomy Teaching -- Chapter 5. From Lecture Halls to Zoom Links: How Can Educational Theory Help Us to Deliver Effective and Engaging Teaching in an Online Environment? -- Chapter 6. Collaborative, Two-Directional Live Streaming to Deliver Hands-on Dissection Experience during the COVID-19 Lockdown -- Chapter 7. Livestreaming Can Augment the Observation of Veterinary Post-mortem Examinations -- Chapter 8. Virtual Reality for Anatomy and Surgical Teaching -- Chapter 9. Can Synchronous Online Near-Peer Teaching Offer the Same Benefits as the Face-to-Face Version When Used in Clinical Neuroanatomy Education? -- Chapter 10. COVID-19 Adaptations with Virtual Microscopy -- Chapter 11. The Challenges of Visualisation During Delivery and Assessment of Clinical Teaching Under COVID-19: A Reflective Account of Problem Solving -- Chapter 12. Not for Room 101.
    Abstract: This book focuses on the challenges to biomedical education posed by the lockdowns and restrictions to on campus teaching brought about by the COVID-19 pandemic and highlights the tools and digital visualization technologies that have been successfully developed and used for remote teaching. Biomedical education for science, medical, dental and allied health professionals relies on teaching visual and tactile knowledge using practice-based approaches. This has been delivered for decades via on-campus lectures, workshops and laboratories, teaching practical skills as well as fundamental knowledge and understanding. However, the arrival of the COVID-19 pandemic meant that education across the globe had to pivot very quickly to be able to deliver these skills and knowledge in a predominantly online environment. This brought with it many challenges, as Higher Education staff, had to adapt to deliver these visual subjects remotely. This book addresses the challenges and solutions faced by Higher Education staff in teaching visual content in distance education. Chapters include literature reviews, original research, and pedagogical reflections for a wide range of biomedical subjects, degrees such as medicine, dentistry and veterinary sciences with examples from undergraduate and postgraduate settings. The goal of the book is to provide a compendium of expertise based on evidence gathered during the COVID-19 pandemic, as well as reflections on the challenges and lessons learned from this dramatic shift in teaching. It also presents new examples of best practices that have emerged from this experience to ensure that they are not lost as we return to on-campus learning in a new era of biomedical teaching. This book will be of interest to anyone looking for a helpful reference point when designing online or blended teaching for visual practice-based subjects.
    Type of Medium: Online Resource
    Pages: X, 228 p. 56 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031171352
    Series Statement: Advances in Experimental Medicine and Biology, 1397
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biomedical Research. ; Cell Biology.
    Description / Table of Contents: Chapter 1. Magnetic Field Parameters and Biological Sample Differences that Lead to Differential Bioeffects -- Chapter 2. Static Magnetic Field Direction-induced Differential Biological Effects -- Chapter 3. Magnetic Properties of Biological Samples -- Chapter 4. Molecular Mechanisms for Electromagnetic Field Biosensing -- Chapter 5. Controlling Cell Membrane Potential with Static Non-uniform Magnetic Fields -- Chapter 6. Impact of Static Magnetic Fields on Cells -- Chapter 7. Impact of Static Magnetic Fields on Microorganisms, Plants and Animals -- Chapter 8. Static Magnetic Fields on Human Bodies -- Chapter 9. Potential Applications of Static Magnetic Fields in Cancer Treatment -- Chapter 10. Effects of Static Magnetic Fields on Diabetes and Its Complications -- Chapter 11. Impacts of Static Magnetic Field on Bone Health -- Chapter 12. Effects of Static Magnetic Fields on the Immune System -- Chapter 13. Biological Effects of Static Magnetic Fields on the Nervous System -- Chapter 14. The Biological Effects of Long-term Static Magnetic Field Exposure -- Chapter 15. Prospects, Pitfalls, and Opportunities for Human Static Magnetic Field Therapy.
    Abstract: The book summarizes the emerging topic about the effects of SMF on biological samples ranging from single molecules, subcellular compartments, and cells to whole organisms. It also discusses the potential application of SMF in clinical treatment of cancer, pain, diabetes and other diseases. With the development and growing popularity of modern appliances like MRI in hospitals, the potential impact of magnetic fields on human health is invoking increasing concerns. At the same time, SMF has been explored in the treatment of tumor and other diseases for decades. Nevertheless, there are still some reservations and uncertainties about these treatments, which are largely due to the differential biological effects reported in the literature. These experimental inconsistencies are mainly caused by variations such as different magnetic field types, intensities, treatment time, as well as biological samples examined. The second edition added eight new chapters about new progress in this field including impacts of SMFs, magnetism of biomolecules, and potential of SMFs in the management of bone, pain, diabetes, and immune systems. This volume will help clarify some dilemmas in this field and encourage further investigations in order to achieve a better understanding of the biological effects of SMF, aiming for a rational application of SMF in clinical therapy in the near future. The book is useful for scientists, doctors, and students who are interested in magnetic fields and life sciences.
    Type of Medium: Online Resource
    Pages: XV, 420 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811988691
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Proteins . ; Cytology. ; Proteins. ; Biomedical Research. ; Protein Biochemistry. ; Cell Biology. ; Proteins.
    Description / Table of Contents: Introduction -- Myosin Structure -- Cargo Binding by Unconventional Myosins -- Cryo-EM of Actin-Myosin Structures -- Small Molecule Effectors of Myosin Function -- Single-Molecule Biophysical Techniques to Study Actomyosin Force Transduction -- High-Speed Atomic Force Microscopy to Study Myosin Motility -- How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches -- How Actin Tracks Affect Myosin Motors -- Myosins in the Nucleus -- Myosins in Cytokinesis -- Myosins and Disease -- Myosins and Hearing -- The Actomyosin Systems in Apicomplexa -- Approaches to Identify and Characterise MYO6-Cargo Interactions -- Class IX Myosins: Motorized RhoGAP Signaling Molecules -- Myosin X -- Myosin XVI -- Myosin XVIII -- Myosin XIX.
    Abstract: Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular activities including cell structure, cell migration, intracellular trafficking, and cell-cell contact. Importantly, loss of function and mutation are associated with diseases including myopathies, hearing impairment, glomerulosclerosis, and cancer. Written by international experts in myosin motors and the approaches used to study them, this book is expected to provide a comprehensive assessment of the current status of our understanding of the structure and molecular mechanism of myosins and their cellular roles.
    Type of Medium: Online Resource
    Pages: XI, 455 p. 116 illus., 97 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030380625
    Series Statement: Advances in Experimental Medicine and Biology, 1239
    DDC: 610.72
    Language: English
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  • 43
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Cancer. ; Biomedical Research. ; Bioinformatics. ; Cancer Biology.
    Description / Table of Contents: Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.
    Abstract: With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.
    Type of Medium: Online Resource
    Pages: VIII, 247 p. 117 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811544941
    Series Statement: Advances in Experimental Medicine and Biology, 1255
    DDC: 610.72
    Language: English
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  • 44
    Keywords: Biotechnology. ; Sustainability. ; Biomaterials. ; Biotechnology. ; Sustainability. ; Biomaterials.
    Description / Table of Contents: Chapter 1_Biomass to liquid fuels: Recent trends in techniques in catalytic conversions -- Chapter 2_Towards sustainable production of hydrogen and biogas from biomass residues -- Chapter 3_ Biorefinery for biofuel production: A Case Study -- Chapter 4_Techno economic analysis and profitability analysis of biofuel production -- Chapter 5_Life cycle analysis and environmnetal impact of bio fuel production -- Chapter 6_Valorization of non lignocellulosic bio waste for BioChemicals -- Chapter 7_State of art technologies for production of biochemicals from biomass -- Chapter 8_Nutraceuticals functional foods and specialty chemicals -- Chapter 9_Technoeconomical analysis of BioChemical production: A Case study -- Chapter 10_Life cycle assessment and sustainability for production of pectin -- Chapter 11_Production of biofertilizers from agro residue: sustainability issues and challenges -- Chapter 12_Utilization of activated carbon obtained from biomass in waste water treatment -- Chapter 13_Sustanability and life cycle assessment of nano-materials from biomass -- Chapter 14_Biorefinery approach for production of enzymes from fruit peel waste -- Chapter 15_Production of Biomaterials: A Case study.
    Abstract: This book discusses recent trends and concepts in the field of biorefinery. It discusses optimal and economic strategies for converting biomass to value-added products to maximize profits with minimal environmental impact with a sustainability approach. The chapters of the book are focused on the current technologies, techno-economical aspects, life cycle assessment, and case studies. The book is divided into three sections; the first section presents strategies for the production of biofuels like bioethanol, biomethane, biohydrogen, bio-oil, gasification, etc., from the biomass in a sustainable way. The second sections review the extraction of bioactive chemicals, phenolic antioxidants, enzymes, and carboxylic acid from the biomass residue. The last section examines the utilization of biomass for the production of bioactive materials, including biofertilizers, bioadsorbents, activated carbon, nano-materials, and pigments. This book explores the relation between biofuels and the sustainable development goals (SDGs) 7.
    Type of Medium: Online Resource
    Pages: XII, 409 p. 56 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811974816
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Neurosciences. ; Medical care. ; Neurology . ; Biomedical engineering. ; Biotechnology. ; Neuroscience. ; Health Care. ; Neurology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1: Application of reinforcement and deep learning techniques in brain machine interfaces -- Chapter 2: Specific muscle activation patterns in athletic and orthopedic populations: considerations for using surface electromyography in assistive and biofeedback device applications -- Chapter 3: Kineto-dynamic modeling of human upper limb for robotic manipulators and assistive applications -- Chapter 4: Learning from the human hand: force control and perception using a soft-synergy prosthetic hand and non-invasive haptic feedback -- Chapter 5: Design of a soft glove-based robotic hand exoskeleton with embedded synergies -- Chapter 6: Model predictive control based knee actuator allocation during a standing-up motion with a powered exoskeleton and functional electrical stimulation -- Chapter 7: Deep brain stimulation for gait and postural disturbances in Parkinson’s disease -- Chapter 8: Cognitive and physiological intent for the adaptation of motor prostheses -- Index.
    Abstract: This book provides a comprehensive review of recent developments in the field of motor neuroprosthetics and brain-machine interfaces. Chapters in this book are provided by leading experts in the field and include topics such as the design and control of multidimensional prosthetics and exoskeletons, deep brain stimulation, functional electrical stimulation, deep learning for brain machine interfaces, biofeedback, and cognitive intent for adaptation of motor prostheses. This book is a great resource for undergraduate and graduate students, researchers, engineers from related disciplines, entrepreneurs, and anyone interested in the latest progress in the field of motor neuroprostheses.
    Type of Medium: Online Resource
    Pages: XII, 162 p. 57 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030387402
    DDC: 660.6
    Language: English
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  • 46
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Microbiology. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Industrial microbiology. ; Biotechnology. ; Microbiology. ; Medical Microbiology. ; Biomedical Research. ; Industrial Microbiology.
    Description / Table of Contents: Chapter 1. The sugar-nucleotide providing enzyme, opportunity and future in the antibody and peptide medicine area -- Chapter 2. The Next Generation of Microalgae-Based Products -- Chapter 3. Advanced techniques for enzymatic and chemical bleaching for pulp and paper industries -- Chapter 4. Commercial bioinoculant development: Techniques and challenges -- Chapter 5. Protein nanostructures with purpose-designed properties in biotechnology and medicine -- Chapter 6. Recent advances in biosynthetic production of Biopigments from microlagae -- Chapter 7. Revealing of the features of the oxidative enzyme production by white-rot basidiomycetes during fermentation of plant raw materials -- Chapter 8. Endophytic bacterial applications in phytoremediation of organic pollutants and toxic metals -- Chapter 9. Biotechnological interventions for Arbuscular Mycorrhizal Fungi (AMF) based biofertilizer: technological perspectives -- Chapter 10. Probiotics and prebiotics: Techniques used and its relevance -- Chapter 11. Techniques of Evaluation of the chemical and microbiological quality of the coastal environment -- Chapter 12. Enzyme engineering techniques for biotechnological applications.
    Abstract: This book compiles the latest research on the multifarious roles of microbial enzymes, and provides an overview of microbial enzymes and biotechnologies. It discusses the use of microbial enzymes in innovative areas like nanomedicine and synthetic biotechnology, as well as the use of starch digesting enzymes and bioactive proteins as biotherapeutics, all of which have applications in modern drug discovery processes. The book also examines the concept of microbial biotransformation and protein engineering, and covers topics such as the immobilization of therapeutic enzymes, bioengineering of enzymes for bioactive compounds, the production of hydrolytic and oxidative enzymes from plant raw materials, and prebiotics and probiotics. Given its multidisciplinary scope, this book will appeal to researchers and industry experts in the fields of microbiology, biotechnology and molecular medicine.
    Type of Medium: Online Resource
    Pages: XIV, 249 p. 83 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811568954
    DDC: 660.6
    Language: English
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  • 47
    Keywords: Biotechnology. ; Food science. ; Biotechnology. ; Food Science.
    Description / Table of Contents: Section A: Food Processing and Technology Innovations -- Chapter 1. Food Innovation and Sustainable Development: A Bio-economics Perception -- Chapter 2. Fermented pearl millet weaning food: an innovation of food technology and application in food processing and management -- Chapter 3. Processing methodologies for few crops in India: Arecanut, betelvine, cashew, cocoa and oil palm -- Chapter 4. Omega 3 fatty acid from plant sources and its application in Food Technology -- Chapter 5. Taizzy Smoked Cheese -- Chapter 6. Plant-Based Milk Substitutes: A novel non-dairy source -- Chapter 7. Makhana: Dry Food and a potential aquatic cash crop.-Chapter 8. An insight over creal β glucan as functional ingredient -- Section B: Food and Industrial Microbiology -- Chapter 9. Rediscovering Medicinal activity and Food Significance of Shogaol (4, 6, 8, 10 and 12): A comprehensive view.-Chapter 10. Exopolysaccarides derived from Beneficial Microorganisms: Antimicrobial, Food and Health benefits.-Chapter 11. Biofilm threat for food and industrial microbiology: An approach for its Elimination Using Herbal food components -- Chapter 12. Cyanobacterial exopolysaccharides as natural source for food packaging application.-Chapter 13. Microbial laccase production and its industrial applications -- Chapter 14. Lichens are the next promising candidates for active compounds.-Chapter 15. Microbial Production and Applications of L-lysine.-Chapter 16. Pomegranate peel: Nutritional values and its emerging potential for use in food systems -- Section C: Food Technology and Environmental Biotechnology -- Chapter 17. Bio-fertilizer from Trichoderma: Boom for Agriculture Production and Management of soil-borne and root-borne plant pathogens -- Chapter 18. Influence of heavy metal on food security: Recent advances -- Chapter 19. Utilization and management of agro and food processing waste -- Chapter 20. Nexus between Climate Change and Food Innovation Technology: Recent Advances -- Chapter 21. Antibiotic Residues in Food: A Global Concern for Human Health -- Chapter 22. Effects of toxicant from pesticides on food security: Current developments -- Chapter 23. Cr pollution, its impact and mitigation -- Chapter 24. Biosorption: A Novel Biotechnological Application For Removal of Hazardous Pollutants -- Section D: Agriculture, Food, Nutrition and Health Security -- Chapter 25. Emerging dichlorvos-based air freshener pertube kidney function in male albino rats -- Chapter 26. Consumption of green chilli& its nutritious effect on human health -- Chapter 27. Synthesis, characterization and evaluation of toxicity of melatonin loaded poly (D, L-lactic acid) Nano-Particles (Mel-PLA-Nano-Particles) and its putative use in osteoporosis -- Chapter 28. Nutritional Physiology -- Chapter 29. Caffeine: Nutraceutical and Health Benefit of Caffeine Containing Commodities and Products -- Chapter 30. Nutraceuticals potential of major edible oilseeds of India -- Chapter 31. Elimination of fungal Leaf Mosaic disease of Bottle Gourd (LagenariaSiceraria ) using Fungo-Phage Therapy: A possible approach for food security with plant protection -- Chapter 32. β- sitosterol - predominant phytosterol of therapeutic potential -- Chapter 33. Odonto-nutraceuticals: Phytochemicals for Oral Health Care -- Chapter 34. Pharmacological potential of thymol -- Chapter 35. TRIKATU- transforming food into medicines -- Chapter 36. Dietary factors associated with cancer. .
    Abstract: This book gathers a collection of essays that describe recent innovations in food technology including food processing, packaging, food safety, and novel ingredients. By 2050, the world will face the challenge of having to feed an estimated 9 billion people. In order to meet that challenge, innovations in food research are of the utmost importance. The book is divided into four sections, each of which explores an important aspect like food processing, food microbiology, and nutritional security. Written by respected scholars in the field, the respective chapters discuss a range of new and enhanced food materials, as well as processing innovations to extend shelf life and reduce toxic effects. The book also addresses the health potential of various nutraceuticals, bio-absorption of metals and their positive impacts on living systems, as well as methods for reducing food wastage, preventing the loss of nutritive value, and preserving or enhancing palatability. Given its scope, the book will be highly interesting for food scientists, both in academia and the food industry. It will also benefit advanced graduate students and senior researchers.
    Type of Medium: Online Resource
    Pages: XXIV, 522 p. 95 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811561214
    DDC: 660.6
    Language: English
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  • 48
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Biomedical Research. ; Pharmacology.
    Description / Table of Contents: Part 1 General and Principles of Toxicology -- A Historical Glimpse and Stalwarts -- General Toxicology -- Principles of Toxicology -- Mechanism of Toxicity -- Part 2 Disposition and Kinetics -- Disposition of Toxicants -- Toxicokinetic of Xenobiotics -- Part3 Organ Toxicity -- Target Organ Toxicity -- Part4 Non-Organ-Directed Toxicity -- chemical carcinogenesis -- Genetic Toxicology -- Developmental Toxicology -- Part5 Toxic Agents -- Pesticides -- Metals and Micronutrients -- Solvents. Gasses and Vapors -- Toxicology of Nanomaterial Particles -- Toxic Effects of Calories -- Part6 Plants, Biotoxins and Food Poisonings -- Plant Toxicity -- Biotoxins and Venomous Organisms -- Poisonous Foods and Food Poisonings -- Part7 Radioactive Materials -- Radiation and Radioactive Materials -- Part8 Applications of Toxicology -- Food Toxicology -- Ecotoxicology -- Environmental Toxicology -- Analytical and Clinical Toxicology -- Occupational Toxicology. .
    Abstract: The book provides easy-to-understand diverse specialized topics in toxicology using self- study questions and answers. The answers are in the form of text along with custom made diagrams and explanations that help the student audience to understand and grasp the matter easily. Problem Solving Questions in Toxicology is written specifically as a study guide for the toxicology board and other examinations. .
    Type of Medium: Online Resource
    Pages: XV, 346 p. 46 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504090
    DDC: 610.72
    Language: English
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  • 49
    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Opportunities for real time monitoring of biomolecules using FRET-based nanosensors -- Chapter 2. Current status of nanosensors in biological sciences -- Chapter 3. Biosensor: An Approach Towards a Sustainable Environment -- Chapter 4. Nanobiosensor in health sector: The milestones achieved and future prospects -- Chapter 5. Nanosensors based on DNA as an emerging technology for the detection of disease -- Chapter 6. Genetically Encoded Nanobiosensors for Nutrients and their applications -- Chapter 7. Development of highly sensitive optical sensors based on Carbon Nanotube (CNTs) -- Chapter 8. Recent advances of Fluorescent Resonance Energy Transfer-based nanosensors for the detection of human ailments -- Chapter 9. Application Of Nanosensors in Agriculture and Food Processing -- Chapter 10. Fluorescent Protein pairs and their application in FRET-based Nanobiosensors -- Chapter 11. Probes for Detection of Free Radicles -- .
    Abstract: This informative book compiles the most up-to-date applications of nanobiosensors in fields ranging from agriculture to medicine. The introductory section describes different types of nanobiosensors and use of nanobiosensors towards a sustainable environment. The applications are divided into four broad sections for easy reading and understanding. The book discusses how manipulation, control and integration of atoms and molecules are used to form materials, structures, devices and systems in nano-scale. Chapters in the book shed light on the use of nanosensors in diagnostics and medical devices. Application in food processing as well as in cell signaling is also described. Nanobiosensors have immense use, and this book captures the most important ones.
    Type of Medium: Online Resource
    Pages: XI, 223 p. 65 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811583469
    DDC: 660.6
    Language: English
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  • 50
    Keywords: Biotechnology. ; Bioinformatics. ; Medical genetics. ; Biotechnology. ; Computational and Systems Biology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Global Alignment of PPI Networks -- Chapter 2: Integrated Network-Based Computational Analysis for Drug Development -- Chapter 3: Effective Random Walk Models for Comparative Network Analysis -- Chapter 4: Computational Methods for Protein-Protein Interaction Network Alignment -- Chapter 5: Network Propagation for the Analysis of Multi_Omics Data -- Chapter 6: Motifs in Biological Networks -- Chapter 7: Bio Fabric Visualization of Network Alignments -- Chapter 8: Module Identification of Biological Networks via Graph Partition -- Chapter 9: Network Module Detection to Decipher the Heterogeneity of Cancer Mutations.
    Abstract: This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights. .
    Type of Medium: Online Resource
    Pages: XII, 217 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571733
    DDC: 660.6
    Language: English
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  • 51
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Zoology. ; Biodiversity. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Ecology. ; Zoology. ; Biodiversity.
    Description / Table of Contents: Introduction: Christopher Clark and Ellen Garland -- Ch 1: Overview. Christopher Clark -- Ch. 2: Anatomy and physiology. Joy Reidenberg -- Ch. 3: Movement, Residency & Migration. Alex Zerbini and Sue Moore,- Ch. 4: Feeding strategies. Ari Friedlaender -- Ch. 5: Molecular genetics. Emma Carroll -- Ch. 6: Social organization. Peter Tyack -- Ch. 7: Ethological and bioacoustic variability. Christopher Clark -- Ch. 8: Baleen whale culture. Ellen Garland and Emma Carroll -- Ch. 9: Blue whale – Global diversity & behavioral variability in a specialist. Ana Sirovic -- Ch. 10: Humpback whale – Global diversity & behavioral plasticity in a court jester. Rebecca Dunlop -- Ch. 11: Humpback whale song - Global diversity & behavioral plasticity in a court jester. Danielle Cholewiak, Sal Cerchio and Ellen Garland -- Ch. 12: Bowhead whale – Acoustic variability in the almost-a-right whale that went north. Kate Stafford -- Ch. 13: Right whales - From north to south, what’s the big difference? Susan Parks -- Ch. 14: Minke Whale – Diversity and variability. Denise Risch -- Ch. 15: Omura’s Whale – An enigma. Sal Cerchio. .
    Abstract: In this book, an international team of leading marine mammal scientists, with a remarkably diverse set of backgrounds and areas of expertise, lead you through a synthesis of current knowledge on baleen whales. Baleen whales are the largest animals ever to have lived on this planet. They also have the lowest and most intense voices on Earth, most likely evolved to take advantage of ocean acoustic transmission conditions so as to be detectable across ocean basins. Some baleen whales can live to be 150-200 years old. They migrate many thousands of kilometers between feeding and breeding areas. They produce songs and calls that serve as behavioral foundations for establishing, maintaining and expanding their cultural identities. To conclude that we know the behavioral limits of these large brained, long-lived animals would be naïve. As baleen whale scientists, we are still beginning to comprehend the enormous complexities and natural histories of these remarkable animals. Today, the fact that whales sing is known throughout much of the world. This awareness started 50 years ago with the publication and popularization of a collection of humpback song recordings that motivated research into baleen whale behavioral ethology. In this book’s chapters, a reader’s experiences will stretch from learning about baleen whale laryngeal anatomy associated with their different voices to learning about the vast ocean areas over which their voices can be heard and the emerging complexities of their culturally defined societies. These are accompanied by chapters on the fundamental ethological contexts of socializing, migrating, and foraging. Two common themes permeate the book. One theme highlights the phenomenal increase in scientific knowledge achieved through technological advancements. The other theme recognizes the impacts of human-made activities on ocean acoustic environments and the resultant influences on the health and survival of individual whales and their populations. Although the book is intentionally ambitious in its scope, as scientists, we fully recognize that baleen whale science is still in its infancy. Many profound revelations await discovery by cohorts of young, multi-talented explorers, some of whom are stretching their wings in this volume and some of whom are reading these scientific stories for the first time.
    Type of Medium: Online Resource
    Pages: XVI, 384 p. 87 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030984496
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    DDC: 577.6
    Language: English
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  • 52
    Keywords: Medicine Research. ; Biology Research. ; Biology. ; Neurosciences. ; Biotechnology. ; Drug delivery systems. ; Biomedical Research. ; Biological Sciences. ; Neuroscience. ; Biotechnology. ; Drug Delivery.
    Description / Table of Contents: Chapter 1.Deciphering New Drug Targets in Alzheimer’s Disease -- Chapter 2. Novel Therapeutic Targets for Treating Alzheimer’s Disease -- Chapter 3. Modified Investigation Tools and Techniques Useful in Alzheimer’s Disease Research -- Chapter 4. Dual Specificity Tyrosine Phosphorylation Regulated Kinase1A (DYRK1A) Inhibitors: The Quest for a Disease-Modifying Treatment for Alzheimer’s Disease -- Chapter 5. β-secretase as a primary drug target of Alzheimer disease: Function, Structure, and Inhibition -- Chapter 6. Endocrine Receptors: The Potential Therapeutic Targets for Alzheimer’s -- Chapter 7. Calcium Channels as a Potential Therapeutic Target for Alzheimer’s Disease -- Chapter 8. Traversing Through the Trajectory of Pathogenic Astrocytes in Alzheimer’s Disease -- Chapter 9. Targeting Mitochondrial Dynamics as a Restorative Approach in the Treatment of Alzheimer’s Disease -- Chapter 10. Epigenetic Therapy for Alzheimer’s Disease -- Chapter 11. Exploring the Diverse Roles of GSK-3ß Kinase in Alzheimer’s Disease -- Chapter 12. Role of Target Fishing in Discovery of Novel Anti-Alzheimer’s Agents: In Silico Applications -- Chapter 13. Multi-Target Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery -- Chapter 14. Investigating the Role of Tau Proteins in Alzheimer’s Disease-From Typical Functioning MAPs to Aberrant Fibrillary Deposits in the Brain -- Chapter 15. The Overview of Drugs Used in Alzheimer’s Disease and Their Molecular Targets.
    Abstract: This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.
    Type of Medium: Online Resource
    Pages: XV, 381 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819926572
    DDC: 610.72
    Language: English
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  • 53
    Keywords: Medicine Research. ; Biology Research. ; Nutrition   . ; Food science. ; Chemistry, Organic. ; Biomedical Research. ; Nutrition. ; Food Science. ; Organic Chemistry.
    Description / Table of Contents: Part I: An overview of cancer and its mechanisms -- 1-A brief overview of cancer, its mechanisms, and prevention methods -- 2-MECHANISMS INVOLVED IN CARCINOGENESIS -- Part II: Functional foods/nutraceuticals as chemo preventive agents -- 3-Tomato (lycopene and β-carotene) and cancer -- 4-Essential Oils from Aromatic Plants in cancer prevention and treatment -- 5-Bee propolis (caffeic acid phenethyl ester) against cancer -- 6-Brown Algae (Fucoxanthin) Against Cancer -- 7-Cruciferous vegetables (indole-3-carbinol, isothiocyanates) against cancer -- 8-Crustacea (carotenoids namely astaxanthins) against cancer -- 9-Curcuma and breast cancer: a focus on cell signaling pathways -- 10-FRUITS AND VEGETABLES IN CANCER -- 11-Garlic: Allyl Sulfur Compounds and Cancer Prevention -- 12-Ginger (gingerols and 6-shogaol) against cancer -- 13-Saffron (crocins) against cancer -- 14-OLIVE LEAF (OLEUROPEIN) AND ITS ROLE IN CANCER: THERAPEUTIC UPDATES -- 15-Honey against cancer -- 16-Soybeans and phytoestrogen rich foods (genistein, daidzein) against cancer -- 17-Tea (catechins including (-)-epigallocatechin-3-gallate) and cancer -- 18-Probiotics and Cancer -- Part III: The role of nutrients in the prevention of cancer -- 19-Vitamins (C, D and E) against cancer -- 20-Minerals (namely selenium) and cancer -- 21-Dietary fibers/beta-glucan and cancer -- 22-Omega-3 Polyunsaturated Fatty Acids and Cancer.
    Abstract: Today's consumers are looking for food products with health-promoting roles in addition to nutritional benefits. With current research showing that nutraceuticals and functional foods rich in specific bioactives may have chemopreventative effects, these products are increasingly popular. However, while much in the literature supports the health-promoting features of these foods, few texts focus on their bioactive agents and their mode of action in cancer signaling. Nutraceuticals and Cancer Signalling: Clinical Aspects and Mode of Action explains the link between nutraceuticals and cancer in terms of clinical trials and modes of action. This book gives an overview of common cancers and their mechanisms, and the most common functional foods and their bioactive components. Individual chapters focus on specific functional foods--including tomatoes, garlic, honey, tea, yoghurt, and many more--their prominent bioactive compounds, and their mode of action in cancer signaling and chemoprevention. Recent findings on cancer-prevention roles of different vitamins and minerals are also discussed. For food scientists, nutritionists, and pharmaceutical experts looking to understand how functional foods can play a role in fighting cancer, this text serves as a one-stop reference.
    Type of Medium: Online Resource
    Pages: IX, 652 p. 52 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030740351
    Series Statement: Food Bioactive Ingredients,
    DDC: 610.72
    Language: English
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  • 54
    Keywords: Medicine Research. ; Biology Research. ; Therapeutics. ; Medical informatics. ; Translational Research. ; Therapeutics. ; Health Informatics.
    Description / Table of Contents: Introduction: The importance of regionalized management of medicine -- Alcohol use disorders -- Public-private partnerships management in health care: The Portuguese experience -- Management of Clinical Precision Medicine -- Artificial Intelligence in medical management -- Advanced Demand Forecasting and Inventory Management Methods in Hospital Pharmacy -- Clinical Application of Cell-Based Therapies Opportunities and Challenges -- Management of Next-Generation Sequencing (NGS) in Precision Medicine -- Exploration on the Reform of County Medical Integration -- The Regionalization of Medical Management: The Practice and Exploration of Established Fudan-Minhang Medical Alliance -- Bed-occupancy management and hospital planning: a handbook -- Management of severe childhood pneumonia in low resource setting -- The role of mitochondrial-targeted antioxidant, MitoQ, in neurodegenerative disease -- Progression of mitochondria research for clinical potentials -- DNA methylation in pulmonary inflammatory diseases -- Synthetic lethality and lung cancer.
    Abstract: The Book mainly focuses on various aspects of regionalized management of medicine, related with updates of new biotechnology, application of therapeutic strategy, and understanding of disease-associated molecular mechanisms. The book also discusses how medical informatics, systems analysis, database sharing, and artificial intelligent can be applied for improving the quality of hospital managements, disease therapies, regional collaborations, and medical services. This book serves as a professional reference book to clinicians and experts who are interested in medical informatics and artificial intelligence for diseases therapies and therapeutic strategy, better systems analysis and database sharing, and more efficient regional collaborations and medical services.
    Type of Medium: Online Resource
    Pages: X, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811678936
    Series Statement: Translational Bioinformatics, 17
    DDC: 610.72
    Language: English
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  • 55
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Toxicology. ; Cytology. ; Biomedical Research. ; Biomedical Devices and Instrumentation. ; Toxicology. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Historical and Technological Background to Organs-on-a-Chip -- Chapter 2. Applications of microfluidics -- Chapter 3. Microfluidics based Organ-on-a-chip for cell biology studies -- Chapter 4. Microfluidics in Chemical biology -- Chapter 5. Role of microfluidics in drug delivery -- Chapter 6. Microfluidics in drug discovery -- Chapter 7. Microfludic based sensors -- Chapter 8. Background and Organs-on-a-Chip -- Chapter 9. Culture and co-culture of cells for multi organ on chip -- Chapter 10.Cells and organs on a chip in biomedical sciences -- Chapter 11. Futuristic aspects of organ on a chip -- Chapter 12. Development of Human on a chip -- Chapter 13. Multi-organ on a chip for personalized medicine -- Chapter 14. Development and application of Microfluids in organoid formation -- Chapter 15. Liver on a chip -- Chapter 16. Placenta on Chip: A Modern approach to probe feto-maternal interface -- Chapter 17. Microfluidic retina-on-chip -- Chapter 18. Heart on a chip -- Chapter 19. Kidney on a chip -- Chapter 20. Lungs on a chip -- Chapter 21. Brain on a chip -- Chapter 22. Skin on a chip -- Chapter 23. Organs-on-a-chip in preclinical studies -- Chapter 24. Application of organ on chip in blood brain barrier model -- Chapter 25. Multi organs on a chip in disease modeling -- Chapter 26. Prospects of Medical device on a chip -- Chapter 27. Lab on a chip for precision Medicine -- Chapter 28. Tumour-on-a-chip : Perfusion systems to model the extracellular breast tumour microenvironment:from tumour progression to metastasis formation -- Chapter 29. Building Human In Vitro 3D Models to Replace Animal Studies: During Drug Discovery Reearch: Scientific, Ethical and Regulatory Considerations.
    Abstract: This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
    Type of Medium: Online Resource
    Pages: IX, 717 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913792
    DDC: 610.72
    Language: English
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  • 56
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Cancer. ; Microtechnology. ; Microelectromechanical systems. ; Biomedical engineering. ; Biotechnology. ; Cancer Biology. ; Microsystems and MEMS. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Part 1 -- Conventional nanosized drug delivery systems for cancer applications -- Homing peptides for cancer therapy -- Radiolabeling of theranostic nanosystems -- Boosting nanomedicine efficacy with hyperbaric oxygen therapy -- Part 2 -- Mesoporous Silica Nanoparticles as Carriers for Biomolecules in Cancer Therapy -- Clearable Nanoparticles for Cancer Photothermal Therapy -- Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds -- Electrospun Nanofibers for Cancer Therapy -- Nanoneedle-based materials for intracellular studies -- Part 3 -- In vitro assays for nanoparticle-cancer cell interaction studies -- 3D tumor spheroid models for in vitro therapeutic screening of nanoparticles -- In vitro and in vivo tumor models for the evaluation of anticancer nanoparticles -- Part 4 -- Nanotechnology for the Development of Nanovaccines in Cancer Immunotherapy -- Viral nanoparticles: cancer vaccines and immune modulators -- Industrial Perspective on Cancer Immunotherapy -- Index.
    Abstract: The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.
    Type of Medium: Online Resource
    Pages: VIII, 360 p. 80 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030581749
    Series Statement: Advances in Experimental Medicine and Biology, 1295
    DDC: 660.6
    Language: English
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  • 57
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Biotic communities. ; Population biology. ; Evolution (Biology). ; Conservation biology. ; Ecology . ; Freshwater and Marine Ecology. ; Biodiversity. ; Ecosystems. ; Community and Population Ecology. ; Evolutionary Theory. ; Conservation Biology.
    Description / Table of Contents: The Coral Tree at the End of the World: Introductory Notes to Coralline Mythology and Folklore from the Indian and Pacific oceans -- The Marine Animal Forests Of South Africa: Importance For Bioregionalisation And Marine Spatial Planning -- Coral and reef fish communities in the thermally extreme Persian/Arabian Gulf: Insights into potential climate change effects -- Marginal reefs in the Anthropocene: they are not Noah’s Ark -- Animal Forests in Submarine Caves -- The Tubeworm Forests of Hydrothermal Vents and Cold Seeps -- Bryozoans: the ‘forgotten’ bioconstructors -- Polychaetes as habitat former: structure and function -- Chemical war in marine animal forests: Natural products and chemical interactions -- The nursery role of marine animal forests -- From Trees To Octocorals: The Role Of Self-Thinning And Shading In Underwater Animal Forests -- Marine animal forests as Carbon immobilizers or why we should preserve these three-dimensional alive structures -- Invasive alien species and their effects on marine animal forests -- Plastics, an additional threat for coral ecosystems -- Visual methods for monitoring mesophotic-to-deep reefs and animal forests: finding a compromise between analytical effort and result quality -- Advances in the Marine Animal Forests Scientific Outreach and Citizen Science.
    Abstract: Marine Animal Forests (MAFs) are spread all over the world. Composed by suspension feeding organisms (e.g. corals, gorgonians, sponges, bryozoans, bivalves, etc.), MAFs constitute a vast number of marine ecosystems such as coral reefs, cold water corals, sponge grounds, bivalve beds, etc. The surface covered by these systems is prominent (at the scale of the oceans of the planet), though poorly known. In a previous book (Marine Animal Forests, the ecology of benthic biodiversity hotspots), several aspects of the MAFs were described and discussed, building the basis for a holistic approach with the aim of putting these shallow and deep sea ecosystems under a common umbrella. The main target of the present book is to identify and address important topics which were not covered in the previous three volumes. Bryozoans or Polychaeta, for example, are treated in this volume, as well as hydrothermal vents ecosystems and submarine caves, the chemical ecology in MAFs or the nursery effect on these ecosystems. The vastity of the MAF concept opens new insights in the biology, physiology, biodiversity of the organisms structuring these highly biodiverse ecosystems and on the dangers threatening them (such as microplastics or the role of invasive species as an impact of their trophic ecology or distribution). In a fast changing world, in which the complexity of MAFs is at risk, we propose an in-depth analysis of many aspects that may be inspirational for future research lines in marine biology and ecology.
    Type of Medium: Online Resource
    Pages: XII, 530 p. 120 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030570545
    DDC: 577.6
    Language: English
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  • 58
    Keywords: Medicine Research. ; Biology Research. ; Diseases. ; Genetics. ; Immunology. ; Biomedical Research. ; Diseases. ; Genetics and Genomics. ; Immunology.
    Description / Table of Contents: Ch 1: Overview of Microbial NGS -- Ch 2: WGS for Bacterial Identification and Susceptibility Testing -- Ch 3: WGS for Bacterial Virulence Assessment -- Ch 4: Epidemiological Typing by WGS -- Ch 5: Bioinformatics Approaches for WGS Analysis -- Ch 6: WGS for Clinical Virology -- Ch 7: WGS for Clinical Mycology -- Ch 8: WGS for Clinical Parasitology -- Ch 9: Long Read Sequencing -- Ch 10: Aspects of WGS Integration -- Ch 11: Microbiome Analysis -- Ch 12: Metagenomics of Environmental Samples -- Ch 13: Clinical Metagenomics -- Ch 14: Metagenomics for Pathogen Discovery -- Ch 15: Advanced Applications for MALDI-TOF: Typing -- Ch 16: Advanced Applications for MALDI-TOF: Infectious Diseases and Antibiotic Susceptibility Testing (AST) -- Ch 17: Omics for Food and Water Microbiology -- Ch 18: Omics for Forensic and Post-Mortem Microbiology -- Ch 19: Omics for Antimicrobial Resistance Surveillance -- Ch 20: Total Laboratory Automation.
    Abstract: Various “omics” methods have recently revolutionized molecular diagnostics. Next-generation sequencing (NGS) makes it possible to sequence a human genome in just one day. Whole genome sequencing (WGS) greatly improves the ability to investigate the outbreaks of numerous pathogens. Metagenomics helps to analyze the microbiome, which aids greatly in identifying the pathogenesis of infectious diseases. Proteomic-based methods, namely matrix-assisted laser desorption-ionization time of flight mass spectrometry (MALDI-TOF-MS), have a promising role in identifying myctobacteria and fungi, and predicting antimicrobial resistance. While there are numerous scientific publications on “omics” applications for microbiology, there are relatively few books that review this topic from a clinical diagnostics perspective. This book looks at this field from a holistic viewpoint, instead of limiting by type of “omics” technology, in order to cover the body of knowledge needed for practitioners and academics interested in clinical and public health microbiology. Additionally, it addresses the management, economical, regulatory and operational aspects of integrating these technologies into routine diagnostics.
    Type of Medium: Online Resource
    Pages: VI, 240 p. 17 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030621551
    DDC: 610.72
    Language: English
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  • 59
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biotechnology. ; Biomedical engineering. ; Biomedical Research. ; Biotechnology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Graviola Fruit Extraction by Ionic Liquid Microwave-assisted Extraction (IL-MAE) -- Role of Ionic Liquids in the Enzyme Stabilization: A Case Study with Trichoderma ressie Cellulase -- Role of Ionic Liquids in the Processing of Lignocellulosic Biomass -- Proliferation of rat amniotic stem cell (AFSC) on modified surface microcarrier -- Application of spectroscopic methods for the analysis of non-halal meats in food products: A narrative review -- Identification of Potential Biomarkers of Porcine Gelatin -- Gamma Ray Mutagenesis on Bacteria Isolated from Shrimp Farm Mud for Microbial Fuel Cell Enhancement and Degradation of Organic Waste -- Effect of temperature on antibacterial activity and fatty acid methyl esters of Carica papaya seed extract -- Solid-state Fermentation of Agro-industrial Waste Using Heterofermentative Lacti Acid Bacteria -- Synthesis of chitosan-folic acid nanoparticles as a drug delivery system for propolis compounds.
    Abstract: This contributed volume, “Multifaceted Protocols in Biotechnology, Volume 2”, consists of multidisciplinary methods and techniques commonly used in biotechnology studies. There are two sections covered in this book – Ionic Liquid Related Techniques & Evergreen Biotechnology Techniques. A brief introduction supports each protocol to allow easy learning and implementation. The first section consists of three chapters covering studies in modern biotechnology focusing on the role of ionic liquid techniques in extracting secondary metabolites, enzyme stabilization and biomass processing. The second section covers evergreen methodologies. It comprises five chapters covering topics on microcarrier technology for cell culture; Polymerase Chain Reaction for non-halal sources detection in food; ELISA for biomarker identification; gamma ray-induced mutagenesis for enhancing microbial fuel cells; and the effect of temperature on antibacterial activity of Carica papaya seed extract. This book will be useful to graduate students, researchers, academics, and industry practitioners working in the area of biotechnology.
    Type of Medium: Online Resource
    Pages: VII, 159 p. 45 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030755799
    DDC: 610.72
    Language: English
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Industrial microbiology. ; Food Microbiology. ; Pharmaceutical chemistry. ; Biotechnology. ; Industrial Microbiology. ; Food Microbiology. ; Pharmaceutics.
    Description / Table of Contents: Module 1. Introduction -- Module 2. Screening of Biosurfactants -- Module 3. Commercial production, optimization and purification -- Module 4. Industrial and environmental applications -- Module 5. Role of biosurfactants in Agriculture and soil reclamation -- Module 6. Toxicity assessment.
    Abstract: This book illustrates the importance and significance of the biosurfactants obtained from microorganisms, preferably from bacteria and yeast. It explains the superiority of biosurfactants (green molecule) over chemically synthesized surfactants for the sustainable future. The content of the present book addresses the quest for novel biosurfactants producing strains, high throughput screening methods, and production strategies. It finely describes the aptness of biosurfactants for industrial and environmental applications. It elaborately describes the technical background and cutting-edge advancement of the commercial aspect of biosurfactants. In the later part of the book, the role of green biosurfactants in food processing, control of food spoilage, incorporation in personal health care products, environmental and agricultural remediation are discussed. Finally, the book elucidates a comprehensive and representative description of toxicity assessment of the biosurfactants, which highlights the risk assessment of the incorporation of the microbial biosurfactants in food, healthcare, and pharmaceutical formulations.
    Type of Medium: Online Resource
    Pages: XI, 194 p. 54 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811627057
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Biomedical Research. ; Medical Genetics. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. General Overview of the Origins and Pathology of Ovarian Cancer -- Chapter 2_An Introduction to the Current Management of Ovarian Cancer in the Era of Precision Oncology -- Chapter 3_The Hallmarks of Ovarian Cancer: Actionable Genetics, Targetable Pathways and Predictive Biomarkers -- Chapter 4_Genetic Alterations in Ovarian Cancer as Prognostic and Predictive Biomarkers of Therapy Response and Surgical Outcomes -- Chapter 5_The Emergence of Circulating Tumor DNA in the Management of Ovarian Cancer -- Chapter 6_Proteomic Biomarkers for Early Detection and Patients’ Stratification in Ovarian Cancer -- Chapter 7_Cutting-edge Technologies and Ovarian Cancer.
    Abstract: This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.
    Type of Medium: Online Resource
    Pages: XV, 229 p. 9 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618734
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biotic communities. ; Biodiversity. ; Population biology. ; Microbial ecology. ; Freshwater and Marine Ecology. ; Ecosystems. ; Biodiversity. ; Community and Population Ecology. ; Microbial Ecology.
    Description / Table of Contents: Chapter 1 Lake Alchichica: History of Human Settlements -- Chapter 2 Geological Evolution of the Alchichica Crater -- Chapter 3 Paleoenvironmental Change in Central Mexico During the Last 20,000 Years -- Chapter 4 Recent Climate of Serdán-Oriental Basin -- Chapter 5 Hydrogeology and Hydrochemistry of the Serdán-Oriental Basin and the Lake Alchichica -- Chapter 6 Meteorological Regime, Local Climate, and Hydrodynamics of Lake Alchichica -- Chapter 7 Physicochemical Characteristics -- Chapter 8 The Littoral Environment -- Chapter 9 Aquatic Vegetation -- Chapter 10 The Littoral Community -- Chapter 11 Bacterioplankton -- Chapter 12 -- Phytoplankton of Alchichica: A Unique Community for an Oligotrophic Lake -- Chapter 13 Protozooplankton -- Chapter 14 Metazooplankton: The Joys and Challenges of Living in a Saline, Oligotrophic, Warm Monomictic Lake -- Chapter 15 Alchichica Silverside -- Chapter 16 -- The Axolotl of Alchichica -- Chapter 17 The Deep Benthic Zone. - Chapter 18 Lake Metabolism. - Chapter 19 Lake Food Webs -- Chapter 20 Diversity and Endemisms -- Chapter 21 Conservation Actions -- Chapter 22 Microbialites: Diversity Hotspots in the Mexican Plateau -- Chapter 23 The Lake Alchichica from an Astrobiological Perspective -- Chapter 24 Lake Alchichica Traditions, Myths, and Legends: Interviews with Local Residents. .
    Abstract: The book provides a comprehensive account of a tropical lake, Alchichica, considering that tropical limnology is by far less well-understood than temperate. Many of the well-known temperate limnology paradigms do not apply in tropical limnology, such as the ≥ 1ºC/m thermocline concept, or the role of phosphorous as limiting nutrient. Lake Alchichica is - most likely – the best limnologically known Mexican lake up to date. Twenty years of continuous monitoring has led us to understand this deep, warm monomictic lake. The peculiar chemical composition of this saline lake – sodium-alkaline with high concentration in magnesium waters, and groundwater-fed – led to the formation of its unique stromatolite ring that has become world-famous, studied by scientists from various countries. From a biological point of view, this relatively small maar lake displays a low species richness, but surprisingly is plentiful in microendemic species for a recently-formed lake (12,000 years old, at the onset of Holocene Epoch), eleven of which already described, with more to come. Researchers and students interested in tropical limnology, extreme ecosystems, evolutionary biology, and microbiology will find this book a must-read.
    Type of Medium: Online Resource
    Pages: XXI, 433 p. 179 illus., 144 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030790967
    DDC: 577.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Drugs Design. ; Pharmaceutical chemistry. ; Genomics. ; Bioinformatics. ; Biomedical Research. ; Structure-Based Drug Design. ; Pharmaceutics. ; Genomics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management.
    Abstract: This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.
    Type of Medium: Online Resource
    Pages: XII, 599 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692321
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Religion and sociology. ; Biotechnology. ; Biotechnology. ; Sociology of Religion.
    Description / Table of Contents: Preface -- Geography, Economy and Nationality of Shimenkan of Weining -- Methodist Churches in Zhaotong -- Shimenkan and Christianity -- Governance of the Miao nationality by the national government in Weining -- The Miao Nationality in Weining in Early People's Republic of China -- Social Reform of the Miao nationality in Weining -- Cooperative and People's Movement in Weining -- Socialist Education Movement" and "the Cultural Revolution" in Weining -- Reform and Opening up of Weining -- Shimenkan after Reform and Opening up -- Conclusion.
    Abstract: This book explores Shimenkan—a Miao-inhabited area in Weining County, China—and its rural society from a comprehensive and long-term perspective, drawing on research conducted by the author in the course of ten years. Located in the northwest of Weining County in Guizhou Province, Shimenkan is a multiethnic area, where, e.g., the Hans, Miaos, Yis, Huis, and Buyis live. Until the early twentieth century, it was a small mountain village; the introduction of Christianity led to significant cultural and social changes in this area. Focusing on China in the twentieth century, the book addresses the traditional culture of the Miao people, the popularity of Christianity in early modern times, the management and control by the government, the socialist reform in the period of the People’s Republic of China, and the changes following the reform and opening-up in recent years. Covering a century’s worth of history, it discusses the major historical events in Northeastern Yunnan and Northwestern Guizhou around Shimenkan and analyzes local social structures, religions, ideologies, customs, and ethnic psychologies, making it a valuable addition to the study of regional social history. The book draws on archives, literature reviews, and field surveys and pursues a multi-disciplinary approach combining history, anthropology, and other disciplines. It offers a valuable resource for researchers in history, religion, and ethnology, as well as readers interested in the spread of Christianity in the Miao-inhabited areas of southwestern China.
    Type of Medium: Online Resource
    Pages: XIV, 273 p. 45 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811989834
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biophysics. ; Senses and sensation. ; Nanoscience. ; Biotechnology. ; Biomedical Research. ; Sensory Systems. ; Nanophysics. ; Chemical Bioengineering.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Bioreceptors -- Chapter 3. Catalytic Biosensors -- Chapter 4. Affinity Biosensors -- Chapter 5. Affinity Biosensors -- Chapter 6. Label-free Biosensors -- Chapter 7. Bioreceptor Immobilization -- Chapter 8. Biochips. Chapter 9. Genome Sequencing -- Chapter 10. Genome Sequencing -- Chapter 11. Micro Electrode Arrays, Implants and Organs-on-a-Chip -- Appendix.
    Abstract: This textbook describes the basic principles and mechanism of action of biosensor systems, and introduces readers to the various types of biosensors; from affinity biosensors to catalytic, optical and label-free biosensors, the most common systems are explained in detail. Dedicated advanced sections focus on biochips and genome sequencing methods as well as organs-on-a-chip. The textbook helps readers to understand the elementary components of biosensors, and to identify and illustrate each function in the biosensor information flow, from recognition to transduction and transmission. Furthermore, readers will receive guidance in critically analyzing published studies on biosensor research, helping them to develop appropriate concepts and independently propose their own solutions. The textbook is intended for master’s students in bioengineering, biophysics, biotechnology and pharmacology that need a solid grasp of biosensor system technologies and applications, as well as students in related medical technological fields.
    Type of Medium: Online Resource
    Pages: XVIII, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030764692
    Series Statement: Learning Materials in Biosciences,
    DDC: 610.72
    Language: English
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    Keywords: Biotechnology. ; Feminism. ; Feminist theory. ; Economic development. ; Biotechnology. ; Feminism and Feminist Theory. ; Development Studies.
    Description / Table of Contents: 1. Introduction -- 2. Environment as a feminist issue -- 3. Silesian coal: history of Silesian industrialisation, the emergence of industrial society and its present restructuring -- 4. Silesian modernizations: analysis of the discourses of change -- 5. Coal perception in the region -- 6. Silesian narratives about the energy and ecology -- 7. The changing roles and values of Silesian women -- 8. Silesian women’s identity: the might of myth -- 9. Women's activity: "I" towards the change -- 10. Post-coal Silesia – the emergence of new regional identity -- 11. Upper Silesia: towards a sustainable future?.
    Abstract: This volume takes an ecofeminist perspective in analysing societal changes related to energy transition, with a focus on Upper Silesia in Europe, following the closure of coal-mining industries in the region. It provides both a macro and micro view of how energy transition in societies built around an energy industry can lead to major shifts in societal and familial dynamics, and how women locate themselves in this transition period affecting the economy as well as social and environmental structures and values. Densely populated Upper Silesia in southern Poland, with one of the longest histories of industrialization, extractivism and environmental degradation in Europe, can be considered as a microcosm of regions that have undergone such changes due to energy transition. The traces of telling socio-economic changes, as well as the tangle of modernity and conservatism, are both clearly visible in the local region and society. The book documents the Silesian changes and highlights the female perspective: their culture, identities, as well as empowerment and the agency. The paradigm of feminist and masculinity studies helps in presenting the complexity and the challenges of the just energy transition. This is a topical volume, given that many regions of the world are undergoing similar changes, and is an interesting read for decision-makers, policy experts, environmentalists, as well social scientists who study issues related to sustainability and environmental/societal challenges in energy transition. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030784164
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Life sciences. ; Cytology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Life Sciences. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: Part I. Search for novel tumor epitopes related to carbohydrates -- Chapter 1.1. The ganglioside structures: chemistry and biochemistry -- Chapter 1.2. Fucosylated proteins as cancer biomarkers -- Part II. Assembly of glycoconjugates -- Chapter 2.1. Siglec-7 and synthetic sialylpolymer -- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis -- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer -- Part III. Signaling pathways modulated by glycosylation -- Chapter 3.1. Significance of FUT8in pancreatic cancer and others -- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells -- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules -- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells -- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction -- Part V. Clinical trials targeting glycosignals -- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.
    Abstract: This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
    Type of Medium: Online Resource
    Pages: VI, 238 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811977329
    DDC: 610.72
    Language: English
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    Keywords: Freshwater ecology. ; Marine ecology. ; Invertebrates. ; Biotic communities. ; Biodiversity. ; Applied ecology. ; Water. ; Hydrology. ; Freshwater and Marine Ecology. ; Invertebrate Zoology. ; Ecosystems. ; Biodiversity. ; Applied Ecology. ; Water.
    Description / Table of Contents: Preface -- Chapter 1: Evolution of Bilateria from a Meiofauna Perspective – Miniaturization in the Focus -- Chapter 2: Meiofauna Shaping Biogeochemical Processes -- Chapter 3: Meiofauna and Biofilms – the Slimy Universe -- Chapter 4: Meiofauna Meets Microbes: Chemosynthetic Symbioses -- Chapter 5: Marine Meiofauna Diversity and Biogeography – Paradigms and challenges -- Chapter 6: Freshwater Meiofauna – a Biota with Different Rules? -- Chapter 7: Hidden Players – Meiofauna Mediates Ecosystem Effects of Anthropogenic Disturbances in the Ocean -- Chapter 8: Deep-Sea Meiofauna – a World of its Own or Deeply Connected? -- Chapter 9: Polar Meiofauna – Antipoles or Parallels? -- Chapter 10: Cave Meiofauna - Models for Ecology and Evolution -- Chapter 11: Meiofauna – Adapted to Life at the Limits -- Concluding Remarks -- Index.
    Abstract: Since research on meiobenthos was last compiled in a textbook (2008/2009), the number of theoretical and applied studies has been growing rapidly. Supported by new methods and digital evaluation, meiobenthology has developed into a wide field, with more and more researchers studying cross-disciplinary aspects. New perspectives were summarized in a booklet (2019) to draw attention to promising research directions. The present book, written by leading experts, is a compilation of new thinking, data, methods and approaches in many relevant fields of recent meiobenthos research. The topics addressed range from bacteria and biofilms to globally changing processes, from polar regions to the deep-sea and from freshwater ecosystems to the ocean. So, this book is not simply another meiobenthos textbook - it is an attempt to identify new horizons in meiobenthos research, driven by the vision of advancing knowledge and understanding of benthic ecosystems.
    Type of Medium: Online Resource
    Pages: XII, 407 p. 49 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031216220
    DDC: 577.6
    Language: English
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    Keywords: Biotechnology. ; Religion and sociology. ; Biotechnology. ; Sociology of Religion. ; Biotechnology.
    Description / Table of Contents: Introduction -- Chapter 1. Religion outside one’s homeland -- Chapter 2. Asylum seekers, immigrants, new Europeans: setting the scene -- Chapter 3. Young foreign Christian Catholics: a portrait -- Chapter 4. Being Muslim in Hard Times in Europe: New Opportunities and Old Challenges -- Chapter 5. God will save us! Faith, identity and practices in refugee welcoming centers -- Chapter 6. Similarities and differences: the Me3 generation at the mirror -- Chapter 7. Does religious capital still matter? Local secularized societies face with a renewal of religious pluralism -- Concluding remarks.
    Abstract: This monograph considers the Catholic/Christian religious identity of young immigrants within the migratory diasporas in Southern Europe. It details important ethnographical work on various groups, such as the family, ethnic communities, and peers. The author also considers the role of institutional figures in mainstream society. These include teachers, administrators, and social workers. This valuable research material helps readers to better understand the viewpoint of young people (especially the children of immigration) in relation to various environments which are important in their lives. The investigation examines theoretical and practical questions regarding the study of relations between religion and migrations. It pays particular attention to both the youth perspective and the effects of the current refugee crisis on the perception of religious diversity and identity. Coverage also looks at similarities and differences between young migrant and their native peers. In addition, three case studies further help illustrate the main points of the author's argument. The book uses preliminary research carried out in Italy. It also features interviews collected in Portugal and Spain. Those interviewed include people with migratory background who are permanent residents, belong to the second generations, or are recently-arrived asylum seekers. Overall, the author provides readers with an interesting and innovative portrait of children of immigrants and their relations with faith in the post-secularized Europe: indeed, by considering both academic debates and original empirical data, the book offers the possibility of reframing the link between migrations and religious identities. .
    Type of Medium: Online Resource
    Pages: XXVII, 130 p. 5 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030840563
    DDC: 660.6
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Medical genetics. ; Biotechnology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Brief Introduction to CRISPR Cas 9 -- Chapter 2: Introduction To Anticipatory Ethics -- Chapter 3: CRISPR, Phenomenology and Lived Experience -- Chapter 4: CRISPR and the Concept of Personhood -- Chapter 5: The use and access to CRISPR in historically socio-economically disadvantaged and marginalized communities -- Chapter 6: Future use of CRISPR: Gene Drive -- Chapter 7: Future use of CRISPR II: CRISPR Kill Switches -- Chapter 8: Domestic and International Regulation of CRISPR -- Chapter 9: Policy Recommendations with respect to CRISPR Germline Editing in Humans -- Chapter 10: Conclusions.
    Abstract: Can we move forward with the use of CRISPR in humans without a well-formed policy and ethical framework to support it? In this new book, neuroscientist Michael W. Nestor and philosopher Richard Wilson argue that the answer is a resounding “no.” Does an ethical and policy program need to be restrictive concerning the use of CRISPR in humans? Nestor and Wilson argue that, although the future of gene editing in humans is inevitable using CRISPR technologies, the scientific, policy, ethics, and clinical communities must work together to provide the necessary frameworks to help CRISPR flourish as an essential tool to treat human disease. To achieve the most inclusive, equitable, and ethically sound use of CRISPR in humans, the scientific/policy/clinical community must involve the most comprehensive set of stakeholders possible, including the lay public. This book sets a framework for shared understanding and discussion across disciplines with an appeal to scientists and non-scientists alike. The authors urge all stakeholders to engage in active dialogue about the appropriate context for using CRISPR and other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, exploring its positive potential to treat mental disorders and the potential to induce other cognitive enhancements.
    Type of Medium: Online Resource
    Pages: XIX, 145 p. 13 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030983680
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Refuse and refuse disposal. ; Environmental engineering. ; Bioremediation. ; Renewable energy sources. ; Biotechnology. ; Waste Management/Waste Technology. ; Chemical Bioengineering. ; Environmental Engineering/Biotechnology. ; Renewable Energy.
    Description / Table of Contents: Part I: Introduction -- Chapter 1. Sustainable technologies for recycling organic solid wastes -- Part II: Production of Biofuels and Chemicals by Thermo-chemical Conversion Processes -- Chapter 2. Recent advances in the catalytic co-pyrolysis of lignocellulosic biomass and different polymer wastes: from laboratory scale to pilot plant -- Chapter 3. Roadmap to Low-Cost Catalytic Pyrolysis of Plastic Wastes for Production of Liquid Fuels -- Chapter 4. Production of Valuable Compounds from Leaves by Supercritical CO2 Extraction -- Part III: Production of Biofuels and Chemicals by Biodegradation -- Chapter 5. Recovery of biohydrogen and biomethane by anaerobic fermentation of organic solid waste -- Chapter 6 Recycling of multiple organic solid wastes into biogas via anaerobic digestion -- Chapter 7. Recycling of multiple organic solid wastes into chemicals via biodegradation -- Part IV Production of Liquid Biofuels with New Technologies -- Chapter 8. Producing value-added products from organic bioresources via Photo-BioCatalytic processes -- Chapter 9. Depolymerisation of fossil fuel and biomass-derived polyesters -- Chapter 10 Producing Value-added Products from Organic Solid Wastes with Mechanochemical Processes -- Chapter 11. Fundamentals of Hydrothermal Processing of Biomass-Related Molecules for Converting Organic Solid Wastes into Chemical Products -- Chapter 12 Third Generation Biorefineries Using Micro- and Macro-Algae -- Part V. Techno-Economic Analysis -- Chapter 13. Prospects and perspectives for producing biodiesel, bioethanol and bio-chemicals from fruit waste: Case study in Brazil and Serbia -- Chapter 14. Sustainable Recycling and Valorization of Organic Solid Wastes for Fuels and Fertilizers.
    Abstract: This book covers sustainable recycling processes (e.g. physical, biological, chemical, and thermo-chemical) of multiple organic solid wastes, provides methods for material recycle of wastes into value-added products including fuels and commodity chemicals that are able to be directly applied to promote manufacturing processes. Aimed at improving the awareness of effective conversion protocols and for developing innovative biomass conversion processes, this text was conceived as a collection of studies on state-of-art techniques and know-how for production of biofuels and chemicals from sustainable recycling of organic solid wastes. Topics in the text are discussed in terms of addressing recent advances, assessing and highlighting promising new methods or new technological strategies and direct conversion of organic solid wastes to process feeds. Highly-recognized authorities, experts and professionals have contributed individual chapters in selected areas to cover the overall topic in a comprehensive manner. .
    Type of Medium: Online Resource
    Pages: XVII, 506 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811661624
    Series Statement: Biofuels and Biorefineries, 11
    DDC: 660.6
    Language: English
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  • 72
    Keywords: Biotechnology. ; Biomaterials. ; Biology Technique. ; Biotechnology. ; Biomaterials. ; Biological Techniques.
    Description / Table of Contents: Introduction to Biobanking -- Scientific Relevance, Problems and the Destitution for Principles of Biobanks and Biobanking Activities -- Types of Biobanks -- Ethical and Legal Principles in the Field of Biobanking -- Business Planning for Biobanks -- Biobanking Concepts Specific for Developing Countries -- Methods of Implementation and Set-up of National Biobanking Networks -- Implementation of Ethical and Legal Considerations in a Biobanking Network -- Collection and Management of Samples -- Quality Control and Risk Management in Biobanks -- Governance and Stakeholder Analysis -- Biobanking IT Systems, Database Structure and Web Applications -- Management Model and Sustainability Plan of Biobanks -- Sustainability Plan and Project Management of a Biobanking Network -- Establishing a Biobank Using Standardisation -- Science and Innovation of Biobanks -- Running a Biobank Network -- Infrastructure: Delivering on the Promise of Biobanking -- Design Considerations and Equipment of Biobanks -- Software Tools for Biobanking in LMICs -- The Importance of Cancer Biobanks in Low- and Middle-Income Countries -- Biobanking in Paediatrics: A Look from Armenia as a Middle-Income Country -- Biobanking of the Central Nervous System -- The Importance of Biobanking COVID-19 Samples -- Oncobiobanking in a Middle-Income Country: The Example of Russia -- Sustainability of Biobanks and Biobanking in LMICs -- Biobanks for Enabling Research and Development by Trusted Patient Data Environment -- Future Perspective of the Biobanking Field.
    Abstract: This book introduces the fundamentals of biobanking and guides through the practical planning thereof, with a special focus on the situation in low- and middle-income countries. On the example of the setup of a Ukrainian biobank the book discusses the main steps and aspects of successful biorepository implementation and management. Topics covered include collection, storage and shipping of samples, establishment of an IT system, development of a sustainability plan, and project and risk management. Furthermore, the importance of the formation of international biobanking societies such as the Ukraine Association of Biobanks is highlighted, and their main objectives and tasks are discussed. The book addresses life science and business professionals as well as national authorities who are interested in biobanking in general and in setting up a biobank in particular.
    Type of Medium: Online Resource
    Pages: XVII, 235 p. 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030876371
    DDC: 660.6
    Language: English
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  • 73
    Keywords: Biotechnology. ; Lipids. ; Food science. ; Biotechnology. ; Lipidology. ; Food Science.
    Description / Table of Contents: Chapter 1. Vegetable Oils and Animal Fats: Sources, Properties and Recovery -- Chapter 2. Exotic Oil: Sources, Properties and Recovery -- Chapter 3. Seed Oil: Sources, Properties and Recovery -- Chapter 4. Vegetable Oil Refining -- Chapter 5. MINOR COMPONENTS IN EDIBLE OIL -- Chapter 6. Blending, Hydrogenation, Fractionation and Interesterification Processing -- Chapter 7. Ionic Liquid as a Green Solvent for Lipid Processing -- Chapter 8. Diacylglycerol Oil: Health Benefits, Synthesis and Applications -- Chapter 9. Medium-and Long-Chain Triacylglycerol: Production, Health Effects and Applications -- Chapter 10. Enzymatic synthesis of human milk fat substitutes -- Chapter 11. Cocoa Butter Alternatives for Food Applications -- Chapter 12. Oleogel: Production and Application -- Chapter 13. Characterization of Nanoemulsions: The Way Forward -- Chapter 14. Processing Contaminants In Edible Oil -- Chapter 15. Enzymatic Biodiesel Production from Low-Quality Waste Oils and Non-edible Oils: Current Status and Future Prospects -- Chapter 16. Sustainability and Traceability in the Malaysian Oil Palm Industry -- Chapter 17. Adulteration in Oils and Fats Industry.
    Abstract: This book is written by international experts with both academic and industrial credentials. It presents for the first time, a collection of up-­to-­date scientific advances in the area of edible fats and oils technology, over a span of 10 years from 2009 to the year 2019. The book covers the existing and recent advanced techniques adopted in the edible fats and oils research and touches on the processing and modification, to the traceability and sustainability issues of fats and oils. Some recent technologies like supercritical carbon dioxide, microwave, ultrasound, and enzymatic‐ assisted processes, ionic liquid, enzymatic processes, biosensor and membrane technology are presented in the book. The book aims to provide the technologists and researchers in research, development and operations in the edible fats and oils industries with critical and readily accessible information on the recent advances in the field. The book is divided into three broad sections- Fats and Oils Chemistry and Processing, Fats and Oils Modification and Health Implications, and Fats and Oils Safety, Social, Environmental and Economic Impacts. It is an extremely comprehensive and valuable resource, which serves as an essential reference for students and lipid scientists from academia or industry.
    Type of Medium: Online Resource
    Pages: X, 492 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811651137
    DDC: 660.6
    Language: English
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  • 74
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Zoology. ; Behavior genetics. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Ecology. ; Biodiversity. ; Zoology. ; Behavioral Genetics.
    Description / Table of Contents: Evolution – Analisa Berta -- Sensory and cognition – Tentative Colleen Reichmuth and others -- Communication – Isabelle Charrier -- Physiology – Dan Crocker -- Movement – Luis Huckstadt and Ryan Reisinger -- Navigation – Patrick Robinson -- Foraging ecology and behavior – Don Bowen -- Reproductive behavior and lactation strategies – Dan Costa and Jen Maresh -- Breeding behavior – Paddy Pomeroy and Kelly Robinson -- Conservation – Samantha Simmons and others.
    Abstract: Phocid (or earless or true) seals are ecologically diverse, occupying habitats from the tropics to the poles in marine and freshwater and feeding on anything from tiny zooplankton to other marine mammals. There are 18 species of phocid seals, the smallest species (ringed seal) is more than 20 times smaller than the largest (southern elephant seal), with marked sexual dimorphism present in some species. This book examines the behavior, ecology, and physiology that allow phocid seals to inhabit such a wide range of habitats. The book is composed of 16 chapters written by 37 authors from 8 countries. The book first describes the general patterns of phocid behavior, followed by descriptions of what is known about well-studied species. We have taken a holistic approach, focusing not only on the behaviors themselves but also on the factors that constrain the expression of behavior and the proximate mechanisms driving behavior. In many cases, the chapters represent collaborations between well-established researchers and early-mid career individuals who bring new perspectives to help carry the field of phocid behavioral ecology well into the future.
    Type of Medium: Online Resource
    Pages: XVIII, 645 p. 180 illus., 161 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030889234
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    DDC: 577.6
    Language: English
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  • 75
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Physiology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Physiology. ; Internal Medicine.
    Description / Table of Contents: Basic structure, physiology and biochemistry of connective tissues and extracellular matrix collagens -- Tendon Extracellular Matrix Assembly, Maintenance and Dysregulation Throughout Life -- Basic Components of Connective Tissues and Extracellular Matrix: Fibronectin, Fibrinogen, Laminin, Elastin, Fibrillins, Fibulins, Matrilins, Tenascins and Thrombospondins -- Proteoglycans and Diseases of Soft Tissues -- Growth Factor Roles in Soft Tissue Physiology and Pathophysiology -- Connective Tissue Disorders and Cardiovascular Complications: The Indomitable Role of Transforming Growth Factor-β Signaling -- The Pathophysiology and Pathogenesis of Marfan Syndrome -- Ehlers-Danlos syndromes, joint hypermobility and hypermobility spectrum disorders -- Ehlers–Danlos Syndrome Associated with Glycosaminoglycan Abnormalities -- Loeys-Dietz Syndrome -- Meester-Loeys syndrome -- Clinical and Molecular Delineation of Cutis Laxa Syndromes: Paradigms for Elastic Fiber Homeostasis -- Collagen VI Muscle Disorders: Mutation Types, Pathogenic Mechanisms and Approaches to Therapy -- Connective Tissue Disorders in Domestic Animals.
    Abstract: This volume represents a substantially revised and updated 2nd edition of a reference handbook on major structural components of soft connective tissues and a whole slew of heritable diseases of soft connective tissues. The number of clearly identifiable and distinct disorders has grown somewhat since the 1st edition in 2014, e.g., Ehlers-Danlos syndrome has now 13 entities. A brand new syndrome, Meester Loeys syndrome carrying the name of Bart Loeys was added as a companion to Loeys-Dietz syndrome. Numerous variations of cutis laxa and joint mobility disorders have been discovered taking advantage of recent advancements in genetic analysis. We have acquired better understanding of pathogenesis and biochemical changes in some other, more established entities, such as Marfan and collagen VI myopathies where better management and possible treatment are on the horizon. Even in the case of connective tissue diseases in domestic animals some progress has been made. All these updates were contributed by a group of distinguished and preeminent physicians and scientists, all of them not just working in the field but making new discoveries described by them. Readers will notice that seemingly there is an overlap among many of these disorders. And indeed, many of them, if not most are interconnected because of the prominent roles of TGFβ, of fibrillin microfibrils and collagen fibril assembly (and other molecules) playing in connective tissues physiology, and by extension in pathogenesis of many disorders described in the book. What I found particularly helpful that author(s) of each chapter bring their own perspective even when described closely related mechanism of the disease. These observations should help with diagnosis and management of such cases. The first chapters are more general, concentrating more on the physiology, structure and biochemistry of normal soft tissues. That should help in better understanding of the pathophysiology. Last but not least, the chapters are very readable, more like detective stories than dry description of genetic/biochemical defects. I do hope that basic scientists and clinicians with similar and diverse interests alike will appreciate this volume and will be inspired by it to develop their research in the field.
    Type of Medium: Online Resource
    Pages: IX, 343 p. 1 illus. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030806149
    Series Statement: Advances in Experimental Medicine and Biology, 1348
    DDC: 610.72
    Language: English
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  • 76
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Life sciences. ; Physiology. ; Agriculture. ; Biotechnology. ; Life Sciences. ; Animal Physiology. ; Agriculture.
    Description / Table of Contents: Chapter 1: Nutrition and Metabolism: Foundations for Animal Growth, Development, Reproduction, and Health -- Chapter 2: Insights into the Regulation of Implantation and Placentation in Humans, Rodents, Sheep, and Pigs -- Chapter 3: A Role for Fructose Metabolism in Development of Sheep and Pig Conceptuses -- Chapter 4: Nutritional Regulation of Embryonic Survival, Growth and Development -- Chapter 5: Phosphate, Calcium, and Vitamin D: Key Regulators of Fetal and Placental Development in Mammals -- Chapter 6: Nutritional and Physiological Regulation of Water Transport in the Conceptus -- Chapter 7: Amino Acids in Microbial Metabolism and Function -- Chapter 8: Potential Replacements for Antibiotic Growth Promoters in Poultry: Interactions at the Gut Level and their Impact on Host Immunity -- Chapter 9: Microbiomes in the Intestine of Developing Pigs: Implications for Nutrition and Health -- Chapter 10: L-Arginine Nutrition and Metabolism in Ruminants -- Chapter 11: Hepatic Glucose Metabolism and Its Disorders in Fish -- Chapter 12: Protein-Sourced Feedstuffs for Aquatic Animals -- Chapter 13: Functional Molecules of Intestinal Mucosal Products in Animal Nutrition and Health -- Chapter 14: Use of Genome Editing Techniques to Produce Transgenic Farm Animals -- Chapter 15: Cows as Bioreactors for the Production of Nutritionally and Biomedically Significant Proteins -- Chapter 16: Use of Agriculturally Important Animals as Models in Biomedical Research -- Chapter 17: Pigs (Sus Scrofa) in Biomedical Research.
    Abstract: This book covers hot topics in the nutrition and metabolism of terrestrial and aquatic animals, including the interorgan transport and utilization of water, minerals, amino acids, glucose, and fructose; the development of alternatives to in-feed antibiotics for animals (e.g., swine and poultry); and metabolic disorders (or diseases) resulting from nutrient deficiencies. It enables readers to understand the crucial roles of nutrients in the nutrition, growth, development, and health of animals. Such knowledge has important implications for humans. Readers will also learn from well-written chapters about the use of new genome-editing biotechnologies to generate animals (e.g., cows and swine) as bioreactors that can produce large amounts of pharmaceutical proteins and other molecules to improve the health and well-being of humans and other animals, as well as the growth and productivity of farm animals. Furthermore, the book provides useful information on the use of animals (e.g., cattle, swine, sheep, chickens, and fish) as models in biomedical research to prevent and treat human diseases, develop infant formulas, and improve the cardiovascular and metabolic health of offspring with prenatal growth restriction. Editor of this book is an internationally recognized expert in nutrition and metabolisms. He has about 40 years of experience with research and teaching at world-class universities in the subject matters. He has published more than 660 papers in peer-reviewed journals, 90 chapters in books, and authored two text/reference books, with a very high H-index of 127 and more than 66,000 citations in Google Scholar. This publication is a useful reference for nutrition and biomedical professionals, as well as undergraduate and graduate students in animal science, aquaculture, zoology, wildlife, veterinary medicine, biology, biochemistry, food science, nutrition, pharmacology, physiology, toxicology, and other related disciplines. In addition, all chapters provide general and specific references to nutrition and metabolism for researchers and practitioners in animal agriculture (including aquaculture), dietitians, animal and human medicines, and for government policy makers.
    Type of Medium: Online Resource
    Pages: VI, 346 p. 43 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030856861
    Series Statement: Advances in Experimental Medicine and Biology, 1354
    DDC: 660.6
    Language: English
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  • 77
    Keywords: Freshwater ecology. ; Marine ecology. ; Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Freshwater and Marine Ecology. ; Microbiology. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: 1. Marine Biotechnology: A Frontier for the Discovery of Nutraceuticals, Energy, and Its Role in Meeting 21st Century Food Demands -- 2. Biotechnological Utilization of the Marine Environment for Food, Drugs and Energy -- 3. Grouper Hybridization: An Effective Biotechnological Tool for Food Security -- 4. The Application of Molecular Markers to Fish Breeding and Aquaculture -- 5. Aquaculture and Applications of Green Seaweeds of the Genus Caulerpa J.V. Lamouroux, 1809 -- 6. Potential and Challenges of Sea Cucumber Holothuria Scabra Mariculture in Sabah, Malaysia -- 7. Sea Cucumber (Echinodermata: Holothuroidea) Species Diversity on the West Coast of Sabah, Malaysia -- 8. Sea Cucumbers: Source of Nutritional, Medicinal, and Cosmeceutical Products -- 9. Marine Biotechnology and its Applications in Drug Discovery -- 10. Bacteriophage as Therapeutic Strategy Against Pathogenic Vibrio -- 11. Bacterial Diversity in the Marine Environment and the Cutting-edge Tools for Isolation, Identification, and Characterization of the Marine Microbiome -- 12. Biotechnological Applications of Jellyfish-Derived Products -- 13. Application of Biotechnology in White Syndrome Coral Disease Identification -- 14. The Synergy of Remote Sensing in Marine Invasion Science -- 15. The Utilization of Agro-based Wastes by Marine Phototrophic Microbes -- 16. Artificial Intelligence Methods in Marine Biotechnology.
    Abstract: This contributed volume covers the applications of marine biotechnology for food, drugs and energy production using marine resources. It introduces many aspects of marine biotechnology, including bioenergy, pharmaceutical development, food security from mariculture, pollution handling, legal issues and conflicts. Information in the book is accompanied by clear images, flow charts, quantitative and qualitative data. Marine biotechnology is essential for realizing the previously untapped potential of marine bio-resources. These resources are used to develop innovative goods and procedures that aid in the global management of food, energy, and disease management. The development of innovative tools and solutions for more sustainable marine environmental management is another important section of this title. This reference book is of interest to teachers, researchers, and climate change scientists. It serves as an additional reading material for college, undergraduate, and graduate students of marine science and aquaculture. This is also a good research guide for food and fishing industry scientists.
    Type of Medium: Online Resource
    Pages: XIII, 354 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819906246
    DDC: 577.6
    Language: English
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  • 78
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Animal biotechnology. ; Physiology. ; Freshwater ecology. ; Marine ecology. ; Animal Biotechnology. ; Animal Physiology. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Chapter 1. Biotechnological Approaches in Fish Health Management -- Chapter 2. RNA Interference and Its Potential Applications in Aquatic Animal Health Management -- Chapter 3. Biotechnological Advances in the Development of Outer Membrane Protein-Based Vaccines for Use in Aquaculture -- Chapter 4. Application Of Carbon Nanotubes In Advancement Of Fish Vaccine -- Chapter 5. Biotechnological Interventions In Developing Vaccines Against Aeromonas Infection In Aquaculture -- Chapter 6. Gene Editing Technology For Fish Health Management -- Chapter 7. Applications of Fish Cell Cultures -- Chapter 8. Recent Advances In Antimicrobial Peptides To Improve Fish Health -- Chapter 9. Gut Microbiome Research: A New Avenue For Aquaculture Disease Management. Chapter 10. Recent Understanding of Immunological Defence in Freshwater Pearl Mussel for Better Health Management -- Chapter 11. Prebiotic-Synbiotic Nexus: Critical Dietary Role in Aquaculture -- Chapter 12. Biofloc Technology: An Eco-Based Emerging Avenue In Aquaculture Health Management -- Chapter 13. Metabolomic Advances in Fish Nutritional Research and Health Management -- Chapter 14. Vaccines to Prevent Diseases in Aquaculture -- Chapter 15. A Progress on Biotechnological Advances on Immunostimulants and Gene Interaction -- Chapter 16. Probiotic Supplements in Aquaculture: Latest Developments & Future Trend -- Chapter 17. Heat Shock Proteins (Chaperones) and Role in Aquatic Animal Disease Management -- Chapter 18. Nanotechnology in Fish Health and Welfare: Recent Advancements and New Perspectives -- Chapter 19. Advances in Management Methods for Argulosis in Aquaculture -- Chapter 20. Metagenomic Approaches to Identify Fish Gut Microbiome and The Effect of Prebiotic Supplements on Gut Microbes and Health Management -- Chapter 21. Microbiome Interventions for The Prevention and Control of Disease Outbreaks in Shrimp Aquaculture. Chapter 22. Reinventing the Micronutrients Beyond Nutrition: Functions in Immune Modulation and Stress Mitigation of Fish -- Chapter 23. Health-Promoting Effects of Amino Acids in Fish -- Chapter 24. Application of Indian Pennywort Centella Asiatica in Carp Aquaculture Against Flavobacterium Columnare Infection.
    Abstract: This book is an inclusive coverage of advances in aquaculture health management. It offers latest updates as well as explains the novel concepts and issues related to aquatic animal health management. To support the understanding of the concepts, there is extensive use of illustrations. Chapters emphasize on the state of art techniques and hold great promise for the sustainable development of aquaculture. This book is of interest to teachers, researchers, aquatic biologists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of aquatic sciences, marine sciences, biotechnology, ecology, and environmental sciences. National and international aquatic scientists, policy makers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XXIV, 579 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811651953
    DDC: 660.6
    Language: English
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  • 79
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Life sciences. ; Chemistry, Organic. ; Enzymology. ; Biochemistry. ; Biomedical Research. ; Life Sciences. ; Organic Chemistry. ; Enzymology. ; Biochemistry.
    Description / Table of Contents: 1. Alkanes, composition, constitution, and configuration -- 2. Functional groups -- 3. Electronic structure of organic molecules -- 4. Alkenes and alkynes -- 5. Substitutions on saturated carbon atom -- 6. Nucleophilic additions -- 7. Stereochemistry, symmetry, and molecular chirality -- 8. Derivatives of carboxylic acids -- 9. Electrophilic substitutions -- 10. Pericyclic reactions -- 11. Organic natural products -- 12. Organic supramolecular and supermolecular structures.
    Abstract: This textbook is designed for students of biology, molecular biology, ecology,medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions.
    Type of Medium: Online Resource
    Pages: XV, 205 p. 339 illus., 114 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030924386
    DDC: 610.72
    Language: English
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  • 80
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Food science. ; Nanotechnology. ; Biomedical Research. ; Food Science. ; Food Engineering. ; Food Nanotechnology.
    Description / Table of Contents: Chapter 1. Chapter 1. Food packaging industry - An introduction -- Chapter 2. Toward Smarter Food Packaging -- Chapter 3. Novel packaging development, assessment and authentication using smart technologies, non-invasive biometric sensory tools, and artificial intelligence -- Chapter 4. Biodegradable packaging materials and techniques to improve their performance -- Chapter 5. Smart Freshness Indicator for Animal Based Products Packaging - Current Status.-Chapter 6. Packaging of dairy products-Emerging strategies -- Chapter 7. Functional packaging materials for fishery products applications -- Chapter 8. Edible films and coatings: Major challenges and potential applications in food Packaging: A Review.-Chapter 9. Role of sensors to improve food/beverage packaging -- Chapter 10. Functional nanomaterials for food packaging applications -- Chapter 11. Rules and regulations related with packaging.
    Abstract: This book reviews the science and technology of food packaging and covers the potential innovations in the food packaging sector. At the same time, it highlights the issues and prospects for linking the laboratory research to the market. In addition to typical packaging requirements such as food quality, shelf life, protection, communication, and marketing, the book emphasizes the need for novel packaging materials, including biodegradable packaging for a variety of food products. A wide range of food products has been kept in focus and includes animal-based food products such as dairy products and sea foods. The book presents the next level of packaging solutions i.e., smart packaging with the applications of potential tools such as intelligent and active packaging, and includes the latest research on emerging digital technologies for packaging development, assessment, and acceptability. It further highlights the strategies including blends, reinforcing agents, cold plasma, UV light applications, chemical, and enzymatic methods and explores the new opportunities leading to improvement in the packaging performance. Smart freshness indicator applications, including gas and time-temperature indicators for quality and safety of packaged products, have been covered in detail. The book also includes the functional characteristics of edible films and coatings, including their bioactive characteristics. Finally the book presents the rules and regulation related to packaging.
    Type of Medium: Online Resource
    Pages: XI, 286 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811671968
    DDC: 610.72
    Language: English
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  • 81
    Keywords: Medicine Research. ; Biology Research. ; Virology. ; Clinical medicine Research. ; Epidemiology. ; Public health. ; Biomedical Research. ; Virology. ; Clinical Research. ; Epidemiology. ; Public Health.
    Description / Table of Contents: Clinical features, diagnostic evaluation and management of COVID-19 patients -- Outbreak of COVID-19: A Detailed Overview and Its Consequences -- A paradigm gap in host-pathogen interaction studies: Lesson from the COVID-19 pandemic -- SARS/CoV-2: Behavioral Host Manipulation -- Management of COVID-19 in the Intensive Care Unit -- First wave of Covid-19 pandemic in Italy: data and evidence -- Risk factors for COVID-19: diabetes, hypertension and obesity -- Current challenges for the effective management of the COVID-19 pandemic -- COVID-19 Outbreak Challenges in Indian Migrant Pregnant and Lactating Mothers: Learnt Lesson Demands Phronesis and Hierarchical Strategies for Such Future Pandemics -- COVID-19 and Extracorporeal Membrane Oxygenation -- COVID-19's Clinical-Pathological Evidence in Relation to its Repercussion on the Central and Peripheral Nervous System -- Anatomopathological Aspects and Clinical Correlation of COVID-19: A Systematic Review -- SARS-CoV-2 liability: the hidden mystery behind its presentation in children.
    Abstract: The book Coronavirus Therapeutics Volume II provides the most comprehensive review on contemporary knowledge on the consequences during the outbreak of Coronavirus. This also describes the clinical features, diagnostic evaluation and management of Coronavirus patients. Using an integrative approach to the understanding of paradigm gap in host-pathogen interaction studies to the management of Coronavirus patients in the Intensive Care Unit to the current challenges for the effective management of Coronavirus pandemic risk factors including diabetes, hypertension, obesity and repercussion on the central and peripheral nervous system. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 241 p. 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851132
    Series Statement: Advances in Experimental Medicine and Biology, 1353
    DDC: 610.72
    Language: English
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  • 82
    Keywords: Medicine Research. ; Biology Research. ; Virology. ; Clinical medicine Research. ; Epidemiology. ; Biomedical Research. ; Virology. ; Clinical Research. ; Epidemiology.
    Description / Table of Contents: Origin and structural biology of Novel Coronavirus (SARS-CoV-2) -- The Molecular Virology of Coronaviruses with Special Reference to SARS-CoV-2 -- Epidemiology, transmission and molecular immunopathology of SARS-CoV-2 -- Epidemiology and Etiopathogeny of Covid-19 -- Immunological and Hematological Response in COVID-19 -- Toll-like receptors (TLRs) as Therapeutic Targets for Treating SARS-CoV-2: An Immunobiological Perspective -- Potential drug strategies to target Coronaviruses -- Possible therapeutic intervention strategies for COVID-19 by manipulating the cellular proteostasis network -- The potential impact of statins in the treatment of patients with COVID-19 infection -- Anticoronavirus activity of water-soluble pristine C60 fullerenes: in vitro and in silico screening -- Application of Nanoscale materials and nanotechnology against viral infection: A special focus on Coronaviruses -- Obesity: A Risk Factor for Covid-19 -- Cytokine Storm and Failed Resolution in COVID-19: Taking Cue from Multiple Sclerosis.
    Abstract: The book Coronavirus Therapeutics Volume I provides the most comprehensive review on contemporary knowledge on the origin, structural biology and molecular aspects of Coronaviruses. It also describes the etiology and pathogeny and therapeutic targets including vaccine drug candidates against Coronaviruses in the light of current scientific knowledge. Using an integrative approach to the understanding of Coronaviruses structure, function and immunobiology, the contributors provide a synopsis of novel mechanisms by which Coronaviruses can be treated. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 222 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851095
    Series Statement: Advances in Experimental Medicine and Biology, 1352
    DDC: 610.72
    Language: English
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  • 83
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biochemical markers. ; Proteins. ; Metabolism. ; Genomics. ; Biomarkers. ; Proteins. ; Metabolism. ; Genomics.
    Description / Table of Contents: Chapter 1. The COVID-19 Pandemic: SARS-CoV-2 Structure, Infection, Transmission, Symptomology and Variants of Concern -- Chapter 2. Long-term Vaccination and Treatment Strategies for COVID-19 Disease and Future Coronavirus Pandemics -- Chapter 3. Consequences of the Lockdown - Domestic Violence during the COVID-19 Pandemic -- Chapter 4. Psychological distress impact of Coronavirus disease (COVID-19) outbreak on three continents: A systematic review and meta-analysis -- Chapter 5. A Molecular Biomarker-based Triage Approach for Targeted Treatment of Post-COVID-19 Syndrome Patients with Persistent Neurological or Neuropsychiatric Symptoms -- Chapter 6. Genetic Associations with Coronavirus Susceptibility and Disease Severity -- Chapter 7. COVID Diagnostics: from Molecules to Omics -- Chapter 8. Assessing Biomarkers in Viral Infection -- Chapter 9. Proteomic Investigation of COVID-19 Severity During the Tsunamis Second Wave in Mumbai -- Chapter 10. NMR-Metabolomics in COVID-19 Research -- Chapter 11. Potential Biomarkers of Mitochondrial Dysfunction Associated with COVID-19 Infection -- Chapter 12. Red Cell Distribution Width as a Prognostic Indicator for Mortality and ICU Admission in Patients with COVID-19 -- Chapter 13. Predicting the COVID-19 Patients Status using Chest CT Scan Findings: A Risk Assessment Model Based on Decision Tree Analysis -- Chapter 14. Inferring Recombination Events in SARS-CoV-2 Variants In Silico -- Chapter 15. Amplicon-based Nanopore Sequencing of Patients Infected by the SARS-CoV-2 Omicron (B.1.1.529) Variant in India -- Chapter 16. Perspectives on Rapid Antigen Tests for Downstream Validation and Development of Theranostics -- Chapter 17. Machine Learning and COVID-19: Lessons from SARS-CoV-2 -- Chapter 18. The Relationship between Psoriasis, COVID-19 Infection and Vaccination during Treatment of Patients -- Chapter 19. Immunogenicity of Inactivated SARS-CoV-2 Vaccine (BBIBP-CorV; Sinopharm) and Short-term Clinical Outcomes in Vaccinated Solid Organ Transplant Recipients: A Prospective Cohort Study -- Chapter 20. Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective -- Chapter 21. Antiviral Mechanisms of Curcumin and its Derivatives in Prevention and Treatment of COVID-19: A review -- Chapter 22. Evaluation of Curcumin-Piperine Supplementation in COVID-19 Patients Admitted to the Intensive Care: A Double-Blind, Randomized Controlled Trial -- Chapter 23. Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases of COVID-19: A Hypothetical Approach -- Chapter 24. The Potential Effect of Royal Jelly on Biomarkers Related to COVID-19 Infection and Severe Progression -- Chapter 25. Statins: Beneficial Effects in Treatment of COVID-19 -- Chapter 26. Multiplex Immunoassay Approaches Using Luminex® xMAP® Technology for the Study of COVID-19 Disease -- Chapter 27. Rapid Detection of SARS-CoV-2 Variants of Concern by Genomic Surveillance Techniques.
    Abstract: The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.
    Type of Medium: Online Resource
    Pages: XI, 513 p. 87 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031280122
    Series Statement: Proteomics, Metabolomics, Interactomics and Systems Biology, 1412
    DDC: 610.72
    Language: English
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  • 84
    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Internal medicine. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Internal Medicine. ; Physiology.
    Description / Table of Contents: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges -- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer -- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk -- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics -- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research -- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions -- Ion Transport and Radioresistance -- Ion Transporting Proteins and Cancer: Progress and Perspectives.
    Abstract: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges Alina L. Capatina, Dimitris Lagos, and William J. Brackenbury Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk Jerry J. Fan and Xi Huang Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu Ion Transport and Radioresistance Bastian Roth and Stephan M. Huber Ion Transporting Proteins and Cancer: Progress and Perspectives Mustafa B. A. Djamgoz.
    Type of Medium: Online Resource
    Pages: X, 277 p. 30 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031039942
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 183
    DDC: 610.72
    Language: English
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  • 85
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biotic communities. ; Landscape ecology. ; Water. ; Hydrology. ; Biodiversity. ; Conservation biology. ; Ecology . ; Freshwater and Marine Ecology. ; Ecosystems. ; Landscape Ecology. ; Water. ; Biodiversity. ; Conservation Biology.
    Description / Table of Contents: Introduction -- Part I. Historical Perspectives -- Vertebrates of Upper Mesopotamia: Present Evidence and Archaeological Data -- Fishing Gears and Methods: A Comparison of Ancient Mesopotamia and Other Ancient Worlds -- Ichthyological Characteristics Available in the Fish Images Existed in the Art of the Ancient Mesopotamia -- The Effectiveness of Ancient Mesopotamian Medical Practices: The Example of šūšu-Licorice -- Part II. The Abiotic Aspects of the Tigris–Euphrates River System -- Management of Water Resources Using Storage Reservoirs -- Estimation of Irrigated Agricultural Area and Water Consumption in Iraq -- The Nature of Tigris–Euphrates Rivers Flow: Current Status and Future Prospective -- Streamflow Alteration Impacts with Particular Reference to the Lower Zab River, Tributary of the Tigris River -- Ecohydrology in Iraq: Challenges and its Future Pathways -- Oil Pollution in the Shatt Al-Arab River and its Estuary 1980–2018 -- Pesticides in the Waters, Sediments, and Biota of the Shatt Al-Arab River for the Period 1980–2017 -- Surface Water Salinity of the Euphrates, Tigris, and Shatt al-Arab Rivers -- Renewable Energy for Water–Energy Nexus in Euphrates and Tigris River Basin: A Literature Review -- Impacts of Dams on Aquatic Biodiversity, Fisheries, Fishes and Their Environment: Problems that Could Be Present in Iraq with Recommendations -- Water, Politics and Dams in the Mesopotamia Basin of the Northern Middle East: How Turkey Instrumentalises the South-Eastern Anatolia Project for Political, Military and Strategic Interests -- Dams and their Impacts on Fishes in Iran -- Part III. The Biotic Aspects of the Tigris–Euphrates River System -- Preliminary Review of the Aquatic Biodiversity in Al-Kahla River, Missan Province, Iraq -- Freshwater Fish Biodiversity in Iraq: Importance, Threats, Status, and Conservation Challenges -- Effect of Climate Changes on the Freshwater Biodiversity in the Mesopotamian Plain: Recommendations for Avoidance and Plans for the Future -- River Corridors as a Refuge for Freshwater Biodiversity: Basic Information and Recommendations to the Policymakers for Possible Implications in Iraq -- Biodiversity of Fungi in Aquatic Environment of Iraq -- Potability of Drinking Water in Basra-Iraq -- Algal Studies in Iraqi Inland Waters. A Review -- The Distribution of Epilitic Diatoms in the Turkish Part of the Tigris-Euphrates River Basin -- Plant Biodiversity in Shatt Al-Arab Estuary and Ecological Variations -- Medicinal Plants of Shatt al-Arab River and Adjacent Area -- The Role of Plants as a Canopy in the Inland Waters: Basic Information for Application in Iraq -- The Zooplankton Fauna of the Turkish Part of the Euphrates-Tigris River Basin -- Kinds and Distribution of Icthyoplankton in Shatt Al-Arab River -- Rotifer Diversity in Iranian Waters: A Review -- Biodiversity of the Freshwater Amphipods in Iran -- The Freshwater Molluscs of the Mesopotamian Plain -- Freshwater Annelida of Iraq -- A Critical Checklist of the Inland Fishes Native to the Euphrates and Tigris Drainages -- Fish Fauna of Shatt al-Arab River, Basrah, Iraq: A More than Quarter a Century of Changes -- The Common Carp, Cyprinus carpio: Effect on the Environment and the Indigenous Fish Species in Iraq -- The Good and the Bad in Releasing the Grass Carp Ctenopharyngodon idella in the Freshwater System: Recommendations for the Policymakers in Iraq -- The Avifauna of Tigris and Euphrates River Basin -- The Feasible Approaches to Assist Migratory Birds Visiting the Southern Reaches of Mesopotamia -- A Proposal for Establishing Bird Observatory Centre in the South of Iraq -- The Potential Role of Waterbirds as a Vector in Dispersing Invertebrates and Plants in the South of Iraq -- The Wild Mammals of the Tigris and Euphrates Rivers Basin -- The Amphibians and Reptiles of Euphrates and Tigris Basin -- A Preliminary Pictorial Guide to the Herpetofauna of Tigris and Euphrates River Basin -- Policy Guidance for Sustainable Aquaculture in the Inland Waters of Iraq -- How Possible to Use the Desert Area in Iraq for Aquaculture Industry: Basic Facts and Recommondations -- Aquaculture Industry in Iraq: Past, Present, and Future Perspectives -- Towards an Improved Tilapia Farming in Iraq: Recommendations for Future Application -- Information and Recommendations of Aquaculture Stress and its Source in Hatcheries: The Iraqi Aquaculture Industry Investors -- Exotic and Invasive Freshwater Fishes in the Tigris-Euphrates River System -- Part IV. Water Resources -- The Ecology and Modelling of the Freshwater Ecosystems in Iran -- Enhancing Rural Women’s Participation in Fisheries in Iraq -- The Impact of Destructive Fishing Gear on the Fish Biodiversity in the Inland Waters of Iraq -- Evaluating Variations in Fisheries by Means of Fishers’ Information: Suggested Methodology to Improve Small-Scale Fisheries in Rivers in Iraq -- A Possibility to Apply a Traditional Fisheries Enforcement Programme in the Inland Waters of Iraq -- Market-Resource Relations and Fish Seller Livelihood as Seen in Inland Waters of Iraq -- The Potential Impact of Deformities in Fishes upon Aquatic Production: Case of Iraq -- The Impact of some Social Taboos on Fisheries in Iraq -- Inland Water Fishes and Fisheries in Iran -- The Possibility of Introducing an Inland Fisheries Education in Iraq -- The Marine and Diadromous Fisheries of Iraq -- Part V. Stress of the Environment of the Two Rivers -- Fish Deformities in the Freshwater Fishes of Iraq: A Short Review and a Study Case on the Indian Catfish Heteropneustes fossilis -- The Phenomenon of Fluctuating Asymmetry: As Fish Welfare Indicator Represented by Case Study from the Freshwater Fishes of Iraq -- The Studies on Sediments Pollution by Different Types of Metals in Turkey -- Macroplastic and Microplastic in the Freshwater Environment of Southern Iraq: Evidences Obtained from Freshwater Fish Species -- Heavy Metals in Freshwater Invertebrates of Iran: A Review on the Bioaccumulation and Effects -- Fish Parasites of Tigris and Euphrates River Systems -- The Parasites of Fishes of the Euphrates and Tigris Rivers: Iraq and Turkey -- Ornamental Fishes: A Looming Danger for Inland Fish Diversity of Iraq -- Part VI. The Health of the Human Community Inhabiting Freshwater Zones -- Aquatic Snails as a Vector of Diseases to the Human in Iran -- Death by Drowning in Rivers in Iraq -- The Dangerous Catfish Species in the Freshwater System of Iraq: First Time Reports on Cases of Envenomation -- Fish Species of the Order Cypriniformes as a Source of Ichthyootoxin and Ichthyogallotoxin in Iraq: Cases Reports -- First Reports on Cases of Hallucinatory Fish Poisoning (Ichthyoallyeinotoxism) and Scombrotoxic Fish Poisoning in Iraq -- Part. VII. Conservation -- Freshwater Management and Conservation in Iran: Past, Present, and Future -- The Need of Biodiversity Conservation Strategies in Iraq: The State of Protected Areas -- Benthic Macroinvertebrates of the Tigris and Euphrates Rivers in Turkey -- Freshwater Ecosystem Conservation in Iraq: Recommendations for Management -- Utilising Phenotypic Difference to Regulate Protection Value: A Scheme for Application of a Novel Approach to the Inland Water of Iraq -- Hatchery-Reared Fish Stocks Released into the Wild: A Conservation Problem as Seen in a Case Study from Iraq -- Part VIII. Social Perspectives -- Is the Glass Half Empty or Half Full? An Appraisal of the Four Decades of Turkey’s Southeastern Anatolia Project (GAP) -- Part IX. Food Security -- How Possible to Build Rice–Fish Farming in Iraq in order to Support Food Security Plan: Positive and the Negative Aspects -- The Importance of Non-commercial and Small-Sized Fish Species: A Proposal for an Additional Revenue to Iraq -- Sociocultural Aspects Influence Food Consumption Habits in Iraq: Management of Food Security -- A Preliminary Investigation of Determinants of Food Security in Rural Areas of Basrah Province, Iraq.
    Abstract: The system of the Tigris-Euphrates Rivers is one of the great river systems of southwestern Asia. It comprises the Tigris and Euphrates Rivers, which follow roughly parallel courses through the heart of the Middle East. The lower portion of the region that they run through is known as Mesopotamia, was one of the cradles of civilisation. There are several environmental factors that govern the nature of the two rivers and shape the landscape the two rivers running through. Geological events create rivers, climate monitor the water supply, the surrounding land influences the vegetation and the physical and chemical features of water. The Tigris-Euphrates system runs through the territory of four countries, Iraq, Iran, Turkey and Syria. Therefore, any scientific approach to the environment of these two rivers should include the natural history events in these countries. The book "Tigris and Euphrates Rivers: Their Environment from Headwaters to Mouth" will be divided into nine parts. These parts deal with the issues of the environment, the status of the flora and fauna, the abiotic aspects, ecology, hydrological regime of the two rivers, the biotic aspects, water resources, stress of the environment, conservation issues. Since the book of Julian Rzoska "Euphrates and Tigris Mesopotamian Ecology and Destiny" in 1980, no book or major reference has been published that includes between its cover the facts and information that the present book will present. Therefore, the importance of the present book falls in stating the present status of the environment of the two rivers and the comparison of their environment between now and that of 37 years ago as given by J. Rzoska (1980). The recent studies showed that there are a large number of natural and political events that happened within the last three decades in the area of the Tigris-Euphrates river system that for sure have done a great change to the environment of the two rivers and consequently changing the biological and non-biological resources of the two rivers. This book will be a reference book to both academic researchers and students across the Middle East in different disciplines of knowledge to use in their researches on Tigris-Euphrates river system. The scholars interested in this area will use this book as a guide to compare this freshwater system with other areas in Asia and the world. .
    Type of Medium: Online Resource
    Pages: XXIII, 1640 p. 387 illus., 317 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030575700
    Series Statement: Aquatic Ecology Series, 11
    DDC: 577.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Neurology . ; Neurosciences. ; Nervous system Diseases. ; Biomedical Research. ; Neurology. ; Neuroscience. ; Neurological Disorders.
    Description / Table of Contents: PART I: Fundamental Aspects -- Chapter 1. Definition of Tremor -- Chapter 2. Membrane Mechanisms of Tremor -- Chapter 3 Advances in the Genetics of Human Tremor -- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor -- PART II:Tremor in Clinical Practice -- Chapter 5. Physiologic Tremor -- Chapter 6. Rest Tremor -- Chapter 7. Postural Tremors -- Chapter 8. Isometric Tremor -- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor -- Chapter 10. Cerebellar lesions and tremor -- Chapter 11. Orthostatic Tremor -- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders -- Chapter 13 Tremor in Childhood -- Chapter 14. Metabolic Causes of Tremor -- Chapter 15. Drug-Induced Tremor -- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis -- PART III: Assessment of tremor -- Chapter 17. Signal Processing -- Chapter 18. Diffusion imaging in Tremor -- Chapter 19. The role of the noradrenergic system in tremor pathogenesis -- Chapter 20. Metabolic Networks in Parkinson’s Disease -- PART IV: Therapies -- Chapter 21. Deep brain stimulation for tremor -- Chapter 22 Mechatronic Devices for Upper Limb Tremor.
    Abstract: Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment and provides practical information for daily management. This new edition is informed by the guidelines of the Tremor Task Force of the International Parkinson and Movement Disorders Society. New chapters include Classification of Tremors, Medically Induced Tremors, Resting State fMRI, and Gabaergic Pathways. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced.
    Type of Medium: Online Resource
    Pages: X, 558 p. 86 illus., 59 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031261282
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Analytical chemistry. ; Toxicology. ; Biomedical Research. ; Analytical Chemistry. ; Toxicology.
    Description / Table of Contents: Microplastic research publications from 1991 to 2020 -- Characterization and toxicology of microplastics in soils, water and air -- Coral feeding behavior on microplastics -- Microplastics remediation in the aqueous environment -- Removal of environmental microplastics by advanced oxidation processes -- Techniques for removal and degradation of microplastics -- Occurrence and removal of microplastics in wastewater treatment plants -- Microplastic souces, transport, exposure, analysis and removal -- Airborne microplastics in outdoor and indoor environments -- Nanoplastic sources, characterization, ecological impact, remediation and policies -- Microplastics in soil-plant systems.
    Abstract: Microplastics and nanoplastics have been recently found in most environmental media and in living organisms, thus representing a serious health concern of yet poorly known adverse consequences. This book summarizes recent findings on the sources, behavior, transformation, toxicity and remediation of microplastics, with focus on soils, water, wastewater, air, soils, plants and corals. Advanced methods for sampling, characterization, removal and degradation of microplastics.
    Type of Medium: Online Resource
    Pages: VIII, 282 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031363511
    Series Statement: Environmental Chemistry for a Sustainable World, 73
    DDC: 610.72
    Language: English
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  • 88
    Keywords: Medicine Research. ; Biology Research. ; Forensic sciences. ; Medical jurisprudence. ; Biomedical Research. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Module 1_Introduction to Forensic Science & Crime -- Module 2_Criminalistics -- Module 3_ Forensic Biological Sciences -- Module 4_Forensic Physical Sciences -- Module 5_Forensic Chemical Sciences -- Module 6_Emerging fields in Trends in Forensics.
    Abstract: This textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tears, sweat, vaginal fluids, urine, and sweat. It also provides an overview of forensic examination of different types of evidence and also includes comprehensive detailing of forensic ballistics including firearm classification, bullet comparison and matching. Further, it explores the examinations of drugs, chemicals, explosives, and petroleum products. It focuses on the various aspects of forensic toxicology, including the study of various poisons/toxins, associated signs and symptoms, a fatal dose /fatal period of poisons. The book also emphasizes digital and cyber forensics, including classification, data recovery tools, encryption and decryption methods, image, and video forensics. It is a useful resource for graduate and post-graduate students in the field of Forensic Science.
    Type of Medium: Online Resource
    Pages: XV, 839 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819913770
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Freshwater ecology. ; Marine ecology. ; Animal culture. ; Biotechnology. ; Animal biotechnology. ; Freshwater and Marine Ecology. ; Animal Science. ; Biotechnology. ; Animal Biotechnology.
    Description / Table of Contents: Chapter 1_ Recent developments in Biosensor Technology for Fisheries and Aquaculture -- Chapter 2_Application of CRISPR-Cas9 Technology in Fish -- Chapter 3_ Nano-technological applications in Aquatic Health Management -- Chapter 4_Phenotypic plasticity and transgenerational immune priming: opportunities and potential in fisheries -- Chapter 5_Heat shock proteins in stress response: a promising tool for fish health management -- Chapter 6_Immunostimulants: Boon for disease management in Aquaculture -- Chapter 7_Molecular markers and their application in fisheries and aquaculture -- Chapter 8_Applications of Electronics in Fisheries and Aquaculture -- Chapter 9_Metatranscriptomics: A tool to study the host-microbe interactions and functional profile of fish intestinal microbiota under changing environmental conditions -- Chapter 10_Bioremediation and its application in aquaculture -- Chapter 11_Application of Probiotics in Aquaculture -- Chapter 12_Identifying novel antibiotic resistance genes (ARGs): Important aspect of metagenomic research.
    Abstract: This edited book is focused on SDG 14: life below water. This book covers all aspects of fish biotechnology and health management. A detailed description is provided of CRISPR Cas9 technology application in the development of superior variety of fish with better growth, disease resistance, etc., accompanied by numerous helpful photographs and schematic diagrams. In addition, recent developments in nanotechnology and its application in fisheries production enhancement have been discussed. Further, topics includes, probiotics, immunostimulants, fish genetic markers, bioremediation, metagenomics, transgenerational immune priming, application of cell culture in fisheries and nano-biosensor application on fish disease diagnosis, pollution monitoring, etc. are provided in details. . The book is helpful for researchers, teachers, students, farmers, and entrepreneurs in utilizing the knowledge on recent advancements in different aspects of fish genetics and biotechnology for future research and aquaculture production enhancement.
    Type of Medium: Online Resource
    Pages: XVIII, 246 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819929818
    DDC: 577.6
    Language: English
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  • 90
    Keywords: Freshwater ecology. ; Marine ecology. ; Ecology . ; Biodiversity. ; Freshwater and Marine Ecology. ; Ecology. ; Biodiversity.
    Description / Table of Contents: Chapter 1_ An Introduction to the Functions and Ecosystems Services associated with aquatic macrophytes -- Chapter 2_ Factors structuring Aquatic Macrophytes -- Chapter 3_ Aquatic Macrophytes: Ecology, Function and Services in Niger Delta, Nigeria -- Chapter 4_ Environmental and Ecological Importance of Indian Aquatic Macrophytes -- Chapter 5_ Macrophytes used as complementary medicines for curing human ailments to facilitate livelihood opportunities -- Chapter 6_ Macrophytes and their role in wetland ecosystems -- Chapter 7_ Ecotoxicology of REEs in aquatic macrophytes and prospect for bioremediation of REEs -- Chapter 8_ Efficiency of Aquatic Plants for Remediation of Wastewater -- Chapter 9_ Phytoremediation of organic contaminants: An ecofriendly approach based application of aquatic macrophytes -- Chapter 10_ Remediation of heavy metals by different aquatic macrophytes -- Chapter 11_ Translocations of heavy metals in aquatic macrophytes naturally grown in the riverine ecosystem -- Chapter 12_ Enhanced Effluent Treatment and Bioelectricity Generation Using Coupled Constructed Wetland-Microbial Fuel Cell (CW-MFC) Technology: Challenges and Opportunities -- Chapter 13_ Role of microbial communities and aquatic macrophytes in constructed wetlands for tannery wastewater treatment: Challenges and opportunities -- Chapter 14_ Role of plant-bacteria association in constructed wetlands for the removal of iron (Fe) from contaminated water. .
    Abstract: This book is a comprehensive collection of information about the features, functions, and services of aquatic macrophytes. As primary producers, aquatic macrophytes form the basis of food webs, play a major role in highly productive aquatic ecosystems, and have a significant impact on ecosystem functions and services. Macrophytes are also known to strongly influence the micro-climate and biogeochemical processes occurring in the littoral zones of marine ecosystems and the sediment dynamics of freshwater systems. They also serve as highly effective carbon sinks and play an important role in carbon sequestration. This book deals with various aspects of aquatic macrophytes, including nutrient recycling, biogeochemical processes, biomass production, wetland ecosystems, water resource management, carbon sequestration, environmental clean-up, and bioenergy production. Additionally, it presents the current status of aquatic macrophytes and discusses the impact of climate change on these plants. The book also highlights the major challenges associated with harnessing the benefits provided by aquatic macrophytes as ecosystem services. The book holds value and relevance for academicians and scientists working in the related domain. Additionally, it will serve as a valuable resource for students and researchers working in the field of ecology, biogeochemistry, wetland conservation, phytoremediation, elements biomonitoring, wastewater management, bioenergy production, etc.
    Type of Medium: Online Resource
    Pages: X, 311 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938223
    DDC: 577.6
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Forensic sciences. ; Toxicology. ; Biomedical Research. ; Forensic Science. ; Toxicology.
    Description / Table of Contents: 1 Forensic Dna Analysis: A Powerful Investigative Tool -- 2 “Crime Scene Management Within Forensic Science-Forensic Techniques For Criminal Investigations -- 3 Small Size, Big Impact: Insects For Cadaver Examination -- 4 Dermatoglyphics & Other Impressions: Deciphering The Potential Of A Unique Hominid Niche -- 5 Postmortem Toxicology: A facet of drugs of expedites crimes -- 6 Forensic Biology: A Passport For Biological Evidence -- 7 Sexual offences: Recent methods of Investigation -- 8 Investigation Of Disaster Victim Identification -- 9 Review On Clinical Forensic Medicine -- 10 Firearms and Ammunitions: A sentient approach in criminal investigation -- 11 Digital and Cyber Forensics: A Contemporary evolution in Forensic Sciences -- 12 Fire Investigation: Arson Or Accidental -- 13 Psychological Evaluations: An Indoor game of Criminal Minds -- 14 Competence of Evidences: A Pragmatic Approach in Court of Law -- 15 Penology: A friend or foe for criminal justice system -- 16 Chain Of Custody: Scaling The Investigation To The Event. .
    Abstract: This book, the second volume of Crime Scene Management in Forensic Sciences, reviews the role and impact of forensic evidence in criminal investigations. It also addresses the importance of post mortem examination in criminal cases. The book investigates the use of insects and arthropods to estimate post mortem intervals during forensic investigations. Further, it discusses the physiological effects of xenobiotics at the time of death, based on their concentration and distribution in the body at autopsy. Importantly, it also discusses digital forensic investigation, which can be used for the analysis of digital evidence produced at a court of law. Lastly, it defines the structure and legal framework of these forensic evidences for the effective administration of the criminal justice system. It is an excellent source of information for forensics scientists and legal professionals.
    Type of Medium: Online Resource
    Pages: VIII, 418 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811666834
    DDC: 610.72
    Language: English
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  • 92
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Molecular biology. ; Metabolism. ; Genetics. ; Cytology. ; Biomedical Research. ; Molecular Biology. ; Metabolism. ; Genetics and Genomics. ; Cell Biology.
    Description / Table of Contents: Introduction (Moray J Campbell & Charlotte L Bevan) -- Overview (Jason Carroll) -- Part I: Reproduction and Development -- Chapter 1. Nuclear receptors in pregnancy and outcomes: clinical perspective (Luiza Borges Manna & Catherine Williamson) -- Chapter 2. Female Reproductive Systems: hormone dependence and receptor expression (Philippa TK Saunders) -- Chapter 3. Nuclear receptors in ovarian function (Darryl Russell & Doan Thao Dinh) -- Part II: Metabolism -- Chapter 4. Nuclear receptors in energy metabolism (Alina Walth, Stephan Herzig & Maria Rohm) -- Chapter 5. Nuclear Receptors and lipid sensing (James L Thorne and Giorgia Cioccoloni) -- Part III: Central Systems -- Chapter 6. Corticosteroid receptors in Cardiac health and disease (Jessica Ivy, Gillian Gray, Megan Holmes, Martin Denvir, Karen Chapman) -- Chapter 7. Physiological convergence and antagonism between GR and PPARγ in inflammation and metabolism (Marija Dacic, Gayathri Shibu and Inez Rogatsky) -- Chapter 8. Circadian Rhythm and Nuclear Receptors (David W Ray) -- Chapter 9. Vitamin D and gut health (James C Fleet) -- Part IV: Cancer -- Chapter 10. Estrogen Receptor alpha and ESR1 Mutations in Breast Cancer (Jaymin Patel & Rinath Jeselsohn) -- Chapter 11. AR structural variants and prostate cancer (Laura Cato) -- Chapter 12. ERβ and inflammation (Linnea Hases, Amena Archer & Cecilia Williams) -- Chapter 13. Genomic insights into non-steroidal nuclear receptors in prostate and breast cancer (Sajad A Wani & Moray Campbell) -- Part V: New developments in transcriptional control by nuclear receptors -- Chapter 14. Protein condensation in the nuclear receptor family; implications for transcriptional output (Monique Appelman, Elle Hollaar, Jurian Schuijers & Saskia WC van Mil) -- Chapter 15. Prostate cancer epigenetic plasticity and enhancer heterogeneity: molecular causes, consequences and clinical implications (Jeroen Kneppers, Andries M Bergman & Wilbert Zwart) -- Chapter 16. Epigenetic coregulation of androgen receptor signaling (Rayzel Fernandes, Damien A. Leach & Charlotte Bevan) -- Part VI: Clinical Translation -- Chapter 17. Cllnical Translation: Targeting the Estrogen Receptor (Jennifer O. Lauchle & Ciara Metcalfe) -- Chapter 18. Drugging the undruggable: targeting the N-terminal domain of nuclear hormone receptors (Marianne Sadar) -- Chapter 19. Genetic Variation and Mendelian Randomization approaches (Mojgan Yazdanpanah, Nahid Yazdanpanah & Despoina Manousaki) -- Index.
    Abstract: This book addresses and dissects the roles and crosstalk mechanisms for the 48 human nuclear receptors (NR) in human health and disease. After a State-of-the-Art introduction by an undisputed and celebrated field leader to provide an overview of the field and its significance, chapters are organized into six sections. The first three sections discuss NR roles in Reproduction & Development, Metabolism and Central Systems. These present to the reader our current understanding of NR signaling in the development and functioning of the reproductive system; the roles in the regulation of energy metabolism; and how NR signaling is more widely integrated into systemic functions from calcium flux to circadian rhythm. The subsequent three sections dissect how aberrant NR functions drive Cancer; how new insights into Genomic Interaction are helping to reveal how NR disruption drives disease; and finally, how Translational Efforts are exploiting this understanding from developing novel NR ligands to establishing how underlying genetic variation impacts NR function. Within these sections the chapters also illustrate emerging understanding of how the epigenome and non-coding genome combine to regulate NR function and impact dysfunction. Increasingly these insights cross-fertilize over cell and disease boundaries and it is unsurprising that NR are being explored in novel and new arenas such as the context of neurological disorders and depression. Thus, there is wide scope for re-purposing of licensed drugs and development of new NR-targeting therapies for a host of conditions and diseases. This unique book brings together many of the leading figures in NR research from across the globe, to discuss emerging roles and their implications for human health and disease. It summarizes the state of the art and shows signposts for future research to further shape this influential field.
    Type of Medium: Online Resource
    Pages: XII, 346 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031118364
    Series Statement: Advances in Experimental Medicine and Biology, 1390
    DDC: 610.72
    Language: English
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  • 93
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Medicine Research. ; Biology Research. ; Anatomy. ; Information visualization. ; Biophysics. ; Biomedical Research. ; Anatomy. ; Data and Information Visualization. ; Bioanalysis and Bioimaging.
    Description / Table of Contents: Chapter 1. The Importance of Integrating the Visual Arts into the Medical Curriculum -- Chapter 2. Using Medical Illustration to Improve Understanding of Endometriosis -- Chapter 3. Editorial Medical and Scientific Illustration -- Chapter 4. Current Approaches in Narrative Medical Visualization -- Chapter 5. Animation for Science Communication: A Description of the Production Process and Contexts for Using Science Animation -- Chapter 6. Effect of the Rings: A Visual Story Design Comparing Three Chemical Characters -- Chapter 7. Diabetes Year One, Random Fluctuations and Mental Goblins: Auto-Ethnographic Pathographies and Medical Comics -- Chapter 8. Playing with Science: Games as a Medium of Science Communication -- Chapter 9. Increasing Microbiology Literacy about the Public Health Threat of Antimicrobial Resistance Through Art-Science Interactions -- Chapter 10. Collaged Creatures: Using Collage Art Practice and Posthuman Ethics to Discuss Bioengineering Hybrids.
    Abstract: This edited book explores the breadth of approaches undertaken by scientists, artists and communicators in their crucial role making science accessible, engaging and impactful. Contemporary approaches in science illustration and visualization include a variety of creative methodologies that are valuable for effective communication, teaching, learning and professional practice. These range in method from anatomical drawings used in medical curricula, to 2D animations and editorial illustrations available in the public realm. They also include unexpected approaches such as the use of tabletop board games, comics and collage in understanding our bodies, emergent health threats and cutting-edge science developments. If you are a scientist seeking to enhance your ability to communicate your research or an artist interested in biomedical visualization, this volume serves as an introduction to contemporary approaches in science illustration and communication. By understanding the creative methods and techniques employed in this field, we can collectively work towards fostering a deeper appreciation of art in science, and continue to captivate and inspire audiences worldwide. .
    Type of Medium: Online Resource
    Pages: XVI, 252 p. 158 illus., 140 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031416521
    Series Statement: Biomedical Visualization, 4
    DDC: 610.72
    Language: English
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  • 94
    Keywords: Biotechnology. ; Molecular biology. ; Agriculture. ; Biotechnology. ; Molecular Biology. ; Agriculture.
    Description / Table of Contents: 1. Bioenergy Crops in the Perspective of Climate Change -- 2. Major and Potential Biofuel Crops -- 3. Biotechnological approaches for the production of Bioenergy -- 4. Integrated OMIC approaches for bioenergy crops -- 5. Genomics of Bioenergy Crops -- 6. Omics Approaches for Sorghum: Paving the Way to a Resilient and Sustainable Bioenergy Future -- 7. Exploring Omics Approaches to Enhance Stress Tolerance in Soybean for Sustainable Bioenergy Production -- 8. Advanced and Sustainable Approaches in Sugarcane Crop Improvements with Reference to Environmental Stresses -- 9. Role of endophytes in the regulation of metabolome in bioenergy crops -- 10. Cotton Stalks - Potential Biofuel Recourses for Sustainable Environment -- 11. Harmful Insects in Some Biofuel Plants and Their Biology -- 12. Perspectives use of mustards in biofuel production in Turkey -- 13. Current status and future prospectus of Bioenergy crops.
    Abstract: This edited book summarizes the efforts made to develop sustainable bioenergy production through different generations. The topics included in the book cover information about different bioenergy crops, their classification and use as biofuel, agronomic practices to improve biomass yield, classic breeding techniques, genetic diversity, current status and future perspective of bioenergy crops in the omics era. It also discusses application of modern biotechnological and molecular biotechnological techniques for the improvement of bioenergy crops this having enhanced biomass and plant based products. The book explores growing biofuel crops and their impact on environment, bioethics and biosafety issues related to the modern approaches. Another important aspect is the incorporation of nanotechnology for bioenergy crops and biofuel production. All book chapters are contributed renowned researchers in their respective field. This is a unique book covering the bioeneragy crops in the modern omics era. The book is useful for the researchers and post-graduate students to guide them in the field of bioenergy crops.
    Type of Medium: Online Resource
    Pages: XV, 288 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819949540
    DDC: 660.6
    Language: English
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  • 95
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Zoology. ; Ecology . ; Oceanography. ; Conservation biology. ; Freshwater and Marine Ecology. ; Biodiversity. ; Zoology. ; Biooceanography. ; Conservation Biology.
    Description / Table of Contents: Part I. Introduction -- Chapter 1. Insights from Cuban Coral Reefs -- Part II. History -- Chapter 2. Research History of Corals and Coral Reefs in Cuba -- Part III. Description -- Chapter 3. Physical-Geographic Characteristics of Cuban Reefs -- Chapter 4. Outline of the Geology, Geomorphology and Evolution of the Late Qua-ternary Shelf and Uplifted Marine Terraces of Cuba; Tectonic and Sea Level Control of Present Day Coral Reef Distribution -- Chapter 5. A Remote Sensing Appraisal of the Extent and Geomorphological Diversity of the Coral Reefs of Cuba -- Part IV. Biota -- Chapter 6. Macrophytes Associated with Cuban Coral Reefs -- Chapter 7. Sponges: Conspicuous Inhabitants of the Cuban Coral Reefs and Their Potential as Bioindicators of Contamination -- Chapter 8. Species List of Cuban Stony Corals: Class Anthozoa, Order Scleractinia; Class Hydrozoa, Suborders Capitata and Filifera -- Chapter 9. Octocoral Forests: Distribution, Abundance, and Species Richness in Cuban Coral Reefs -- Chapter 10. Current State of Knowledge of Reef Mollusks in Cuba -- Chapter 11. Herbivory on Cuban Coral Reefs -- Chapter 12. Chronology of the Lionfish Invasion in Cuba and Evaluation of Impacts on Native Reef Fishes -- Chapter 13. Sharks and Rays in Cuban Coral Reefs: Ecology, Fisheries, and Conservation -- Chapter 14. Mesophotic Coral Ecosystems of Cuba -- Part V. Ecology, Conservation and Management -- Chapter 15. Status of Cuban Coral Reefs -- Chapter 16. Population Genetics of Cuba’s Scleractinian Corals -- Chapter 17. Multiple Cumulative Effects on Coral Reefs of the Northwestern Cuban Region -- Chapter 18. Guanahacabibes National Park: Research, Monitoring and Man-Agement for the Conservation of Coral Reefs -- Chapter 19. Ciénaga de Zapata Biosphere Reserve: Integrating Science with the Management of Coral Reefs -- Chapter 20. Coral Reefs in Cuban Marine Protected Areas -- Part VI. Economic Valuation -- Chapter 21. Economic Valuation of the Coral Reefs of Jardines de la Reina and Punta Francés National Parks, Cuba -- Chapter 22. The Economic Value of Coral Reefs in the Context of Marine Protected Areas: Experiences of the South Cuban Archipelago Project -- Chapter 23. Fish Can Be More Valuable Alive Than Dead.
    Abstract: This comprehensive volume gathers foremost experts on the coral reefs of Cuba who represent a spectrum of disciplines, including biology, conservation ecology, economics and geology. The volume is organized along general themes including the Cuban Reef biota, reefs occurring in the Mesophotic and Eutrophic zones, ecology, conservation, management and the economic importance of the coral reefs of Cuba. The combination of case studies, new and previously published research, historical overview and examples of the ways in which research has contributed to the management and conservation of Cuban coastal resources provides a unique reference for graduate students and professionals holding a wide range of interests and expertise related to coral reef systems.
    Type of Medium: Online Resource
    Pages: XI, 438 p. 176 illus., 147 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031367199
    Series Statement: Coral Reefs of the World, 18
    DDC: 577.6
    Language: English
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  • 96
    Keywords: Medicine Research. ; Biology Research. ; Regenerative medicine. ; Biomaterials. ; Biomedical Research. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials.
    Description / Table of Contents: Chapter 1. An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells -- Part I. Structural Scaffolds and Bio-activation -- Chapter 2. Polymeric and Biomimetic ECM Scaffolds for Tissue Engineering Applications -- Chapter 3. Versatile Hydrogels in Regenerative Medicine -- Chapter 4. Multilayer Microcapsules with Tailored Structures and Properties as Delivery Carriers for Drugs and Growth Factors -- Part II Biomaterials Surfaces/Interfaces and Bio-interactions. Chapter 5. Interactions of Biomaterial Surfaces with Proteins and Cells -- Chapter 6. Surface Modification of Tissue Engineering Scaffolds -- Chapter 7. Gradient Biomaterials and Their Impact on Cell Migration -- Chapter 8. Stem Cell Differentiation Mediated by Biomaterials/Surfaces -- Part III Regeneration of Some Clinic-Targeted Tissues -- Chapter 9. Cartilage Regeneration -- Chapter 10. Skin Regeneration -- Chapter 11. Regeneration of Blood Vessels -- Chapter 12. Cardiac repair and regeneration -- Chapter 13. Nerve Regeneration.
    Abstract: This book reviews state of the art of polymeric biomaterials for regenerative medicine and highlights advances in both fundamental science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physiochemical property modulation, as well as their influence on the adhesion and performance of biomolecules, cells, and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies. In the second edition, most of the chapters are updated according to the latest progress of this research field. A new chapter on nerve regeneration is also included.
    Type of Medium: Online Resource
    Pages: VIII, 577 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789819969487
    DDC: 610.72
    Language: English
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  • 97
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Ecology . ; Oceanography. ; Bioclimatology. ; Environmental management. ; Freshwater and Marine Ecology. ; Biodiversity. ; Biooceanography. ; Climate Change Ecology. ; Environmental Management. ; Ocean Sciences.
    Description / Table of Contents: Chapter 1. A Global View of the Cold-Water Coral Reefs of the World -- Chapter 2. Biology, Ecology and Threats to Cold-Water Corals on Brazil’s Deep-Sea Margin -- Chapter 3. Cold-Water Corals of the World: Gulf of Mexico -- Chapter 4. Cold-Water Coral Reefs of the Southeastern United States -- Chapter 5. Norwegian Coral Reefs -- Chapter 6. Waters of Ireland and the UK -- Chapter 7. Life and Death of Cold-Water Corals across the Mediterranean Sea -- Chapter 8. Cold-Water Coral Reefs in the Oxygen Minimum Zones off West Africa -- Chapter 9. New Zealand: South West Pacific Region -- Chapter 10. Deep-Sea Corals of the North and Central Pacific Seamounts.
    Abstract: Cold-water corals form reef structures in continental margin and seamount settings world-wide, making them more wide-spread and abundant than shallow-water reefs. Their role in these ecosystems is no less important than the influence that shallow-water coral reefs have on tropical systems. They create habitat structure, host endemic species, enhance elemental cycling, alter current flow, sequester carbon, and provide many other ecosystem services that we are just beginning to understand. The rapidly evolving state of knowledge of cold-water and deep-sea coral reefs has not been compiled in over 10 years. This volume synthesizes recent and historical information, reveals new findings from reefs that have been discovered only recently, and presents key avenues for future research. We are on the cusp of understanding the critical role that cold-water coral reefs play in the world’s oceans, and this book lays the foundation on which this knowledge will be built in the future.
    Type of Medium: Online Resource
    Pages: XVI, 293 p. 107 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031408977
    Series Statement: Coral Reefs of the World, 19
    DDC: 577.6
    Language: English
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  • 98
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Biotechnology. ; Plant genetics. ; Environmental policy. ; Biotechnology. ; Plant Genetics. ; Environmental Policy.
    Abstract: This book is a translation of an original French edition. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. The evolution of genome’s modification by genetic engineering was characterized by a major technological breakthrough with the discovery of CRISPR in 2012. A distinction is now made between first-generation biotechnologies developed in the 20th century and current second-generation biotechnologies, NGT or New Genomic Techniques, including genome editing. How do we consider these genomic modifications compared to those that occur spontaneously in nature? What are the applications of these techniques in the fields of plants, animals, and human health? What prospects in terms of development and independence for countries and at least what regulations are in force on the different continents? The book questions what GMOs are, genome editing products and the place of genomic transformations today and tomorrow in our societies. It tries to give some geostrategic and regulatory benchmarks on biotech products in order to better understand the current issues.
    Type of Medium: Online Resource
    Pages: XXI, 157 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031382376
    DDC: 660.6
    Language: English
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  • 99
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Zoology. ; Sustainability. ; Population biology. ; Conservation biology. ; Ecology . ; Freshwater and Marine Ecology. ; Biodiversity. ; Zoology. ; Sustainability. ; Population Dynamics. ; Conservation Biology.
    Description / Table of Contents: Part I. Fish Resources and Fishing Areas of the Western Balkans -- Chapter 1. Fish Resources of Inland Waters and Fisheries in Slovenia, Management, Sustainability and Conservation -- Chapter 2. Inland Fisheries in Croatia: Historical Aspects, Fish Resources, Management and Conservation -- Chapter 3. Fish Resources and Fisheries in Bosnia and Herzegovina – Overview, Sustainability, and Conservation -- Chapter 4. Inland Fisheries in Serbia: Historical Aspect, Fish Resources, Management and Conservation -- Chapter 5. The Freshwater Fish Resources and Freshwater Fisheries of Montenegro, Management, Sustainability and Conservation – With a Special Perspective on Lake Skadar -- Chapter 6. Fish and Fisheries of the Republic of North Macedonia, Current Situation and Its Perspective -- Chapter 7. Fish Resources of Inland Waters and Fisheries in Albania, Management, Sustainability and Conservation -- Part II. Some Fish Species of the Western Balkans Important for Fisheries and Conservation -- Chapter 8. Freshwater Crayfish of Western Balkan: Is It Possible to Use Them Sustainably or Do They Need Prompt Conservation Actions? -- Chapter 9. Salmonid Fish Species – Opportunities for Sustainable Use under Multiple Pressures and Current Climatic Change -- Chapter 10. Past and Future of Sturgeon Species (Acipenseridae) in Western Balkans – Case for Permanent Conservation or Sustainable Management -- Part III. Effects of Stressors on Inland Water Ecosystems and Fish Resources -- Chapter 11. Eutrophication of Fishing Waters and the Influence of Cyanobacterial Occurrence and Blooming on Fish Resources – Case Studies in Serbia -- Chapter 12. Pollution of Fishing Waters of the Western Balkan – Potentially Toxic Elements and Their Impact on the Ecological Sustainability of Fish Resources -- Chapter 13. Invasive Macroinvertebrate and Fish Species and Their Impact on Fish Resources: A Case Study on Fishing Waters of Serbia -- Part IV. Fish Stock Assessment Methods -- Chapter 14. A Brief Overview of the Development of the ES-HIPPO Model for Assessing the Sustainability and Conservation Priorities of Fish, Fish Resources, and Inland Water Habitats -- Part V. Conservation and Aquaculture -- Chapter 15. Тhe Role and Importance of Aquaculture for the Ecological Sustainability of Fish Resources in the Inland Water of Serbia -- Chapter 16. Huchen Hucho hucho (Linnaeus, 1758) in Croatia: Distribution, Genetic Diversity, Threats and Conservation -- Chapter 17. Future Perspective of Sustainable Development of Freshwater Fisheries and Conservation of Threatened Fish Species, Crustaceans and Molluscs -- Part VI. Social Aspect -- Chapter 18. Political and Socio-Economic aspects of Fisheries in Inland and Coastal Waters of the Western Balkan -- Chapter 19. Fish Resources of the Western Balkans, Sustainable Use and/or Conservation?.
    Abstract: This book provides a detailed evaluation of the hydro-ecological characteristics of the Western Balkans, an area characterized by still preserved inland waters and fish resources important for the European continent, as well as the biodiversity of inland waters important for the planet Earth. Freshwater ecosystems cover only 1% of the Earth's surface; however, they are a habitat for about 40% of fish species. At the same time, inland fisheries make less than 12% of the world's global fish catch, with 43% coming from low-income and food-deficient countries (Africa, South America, Southeast Asia). In Europe, the Western Balkans have significant fishing waters and fish resources, including the Middle Danube drainage (Sava, Drina, Velika Morava river systems), large ancient lakes (Skadar/Shkodra, Ohrid, Prespa, Dojran), and the Adriatic basin characterized by endemic and commercially important species. However, in contrast to the high fishing potential in a significant part of the Western Balkans, diverse and specific political, economic, and social factors largely had a negative impact on the state of fish resources. This volume is multidisciplinary and provides a sound knowledge base for scientific and practical fisheries. In addition, it may be a valuable guide for managers and conservationists worldwide to adapt methods and procedures for the ecological sustainability of fish resources under specific local, natural, and socio-economic conditions. Finally, the content is a good reference for natural sciences and agriculture students studying fish, fish resources, and fisheries sciences. It would improve their knowledge and perspectives on the challenges of sustainable use and conservation of inland water resources.
    Type of Medium: Online Resource
    Pages: XXII, 707 p. 261 illus., 233 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031369261
    Series Statement: Fish & Fisheries Series, 43
    DDC: 577.6
    Language: English
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  • 100
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Proteins . ; Cytology. ; Biomedical Research. ; Protein Biochemistry. ; Cell Biology.
    Description / Table of Contents: Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and Cancer Immunotherapy -- Chaperonin Hsp60 and Cancer Therapies -- Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment -- Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics -- Multifaceted Roles of Heat Shock Factor 1 (HSF1) in Cancer -- Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer -- Heat Shock Proteins in Atrial Fibrillation -- Threading Microarrays into Novel Applications -- Regulation of Kaposi’s Sarcoma-associated Herpesvirus Biology by Host Molecular Chaperones -- Role of Heat Shock Factors in Diseases and Immunity -- Heat Shock Proteins and Pain -- Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway -- Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with diverse Cellular and Molecular Functions -- Roles of Heat Shock Proteins on Antigen Presentation -- Heat shock proteins mediate anastasis and plasticity of thermotolerant cells.
    Abstract: The book Heat Shock Proteins in Human Diseases provides the most comprehensive review on contemporary knowledge on the role of heat shock proteins (HSP) in various types of human diseases including cancer, cardiovascular disease, microbiology and inflammation. These diseases were specifically chosen due to their dismal prognosis, the survival benefit offered by the current standards do not greatly impact the overall survival statistics with the disease and are associated with toxicity. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in human diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 297 p. 31 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030622893
    Series Statement: Heat Shock Proteins, 21
    DDC: 610.72
    Language: English
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