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  • 1
    Online Resource
    Online Resource
    Medicinal and Aromatic Plants of North America (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Agriculture. ; Plant physiology. ; Plant Science. ; Agriculture. ; Plant Physiology.
    Description / Table of Contents: Chapter 1. Introduction to MAPs in the North America -- Chapter 2. Dr. Duke's Phytochemical and Ethnobotanical databases, a cornerstone in the validation of ethnoveterinary medicinal plants, as demonstrated by data on pets in British Columbia -- Chapter 3. Pharmacopoeial Wild Medicinal Plants of North America -- Chapter 4. Medicinal Plant Products, a Discussion of Actual or Probable versus Perceived Sources -- Chapter 5. Juniper species in North America to the same species in Europe with respect to phytochemistry and bioactivity -- Chapter 6. Mentha Genetic Diversity at the US National Clonal Germplasm Repository in Corvallis, Oregon -- Chapter 7. Advances in the research of basil -- Chapter 8. Advances in ther research of catnip -- Chapter 9. Diversity, conservation and sustainable harvest of medicinal plants in North America -- Chapter 10. The Great botanist, Jim Duke -- Chapter 11. TBC -- Chapter 12. Taxol or the story of the American yew -- Chapter 13. The Indian Tobacco -- Chapter 14. The American Elderberry -- Chapter 15. The American Ginseng.
    Abstract: This volume is aimed at offering an insight into the present knowledge of the vast domain of Medicinal and Aromatic Plants with a focus on North America. In this era of global climate change the volume is meant to provide an important contribution to a better understanding of the diverse world of Medicinal and Aromatic Plant research, production and utilization.
    Type of Medium: Online Resource
    Pages: VIII, 342 p. 59 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030449308
    Series Statement: Medicinal and Aromatic Plants of the World, 6
    URL: https://doi.org/10.1007/978-3-030-44930-8
    DOI: 10.1007/978-3-030-44930-8
    DDC: 580
    Language: English
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  • 2
    Online Resource
    Online Resource
    A Monograph of Paris (Melanthiaceae) : Morphology, Biology, Systematics and Taxonomy (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Plant genetics. ; Plant ecology. ; Plant Science. ; Plant Genetics. ; Plant Ecology.
    Description / Table of Contents: Preface -- Acknowledgement -- Chapter 1. Taxonomic History -- Chapter 2. Morphology -- Chapter 3. Biology -- Chapter 4. Economic Importance -- Chapter 5. Phylogeny, classification, and biogeography -- Chapter 6. Taxonomic revision -- Chapter 7. Conservation status.
    Abstract: This book provides essential information on the morphology, biology, phytochemistry, pharmaceutical prospects, evolution, phylogeny, biogeography, and taxonomy of Paris (Melanthiaceae), a morphologically distinctive plant genus with great economic importance. Since the establishment of this genus, 70 species and 24 subspecific taxa have been described, resulting in considerable confusion in species delimitation. In this book, the taxonomy of all described taxa is carefully revised. Based on multi-disciplinary evidences, a revised classification system of Paris containing five sections is outlined. Every species is provided with a concise but diagnostic description, a color illustration, photographs that highlight distinguishing characters, examined specimens and distribution range. The interspecific relationships are clarified with an identification key. This monograph offers taxonomists, evolutionary biologists, ecologists, horticulturalists, phytochemists, and practitioners a thorough and up-to-date overview about this interesting plant group. It is equally valuable for undergraduate and graduate students, teachers and professionals engaged in related fields.
    Type of Medium: Online Resource
    Pages: XIII, 203 p. 134 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811579035
    URL: https://doi.org/10.1007/978-981-15-7903-5
    DOI: 10.1007/978-981-15-7903-5
    DDC: 580
    Language: English
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  • 3
    Online Resource
    Online Resource
    ESR Spectroscopy for Life Science Applications: An Introduction (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Radiology. ; Spectrum analysis. ; Pharmaceutical chemistry. ; Nutrition   . ; Biomedical Research. ; Radiology. ; Spectroscopy. ; Pharmaceutics. ; Nutrition.
    Description / Table of Contents: Ch 1: Electron Spin Resonance- An Introdcution -- Ch 2: ESR – Applications in Healthcare and Pharmaceutical Science -- Ch 3: ESR Applications in Paleontology and Geochronology -- Ch 4: ESR Applications in Food Science.
    Abstract: This book introduces the audience with basic theoretical and experimental aspects of Electron Spin Resonance (ESR) Spectroscopy. It further talks about ESR spectroscopy applications in Healthcare & Pharmaceutical Science, Paleontology & Geochronology and Food Science. Mathematical details have been kept to a necessary minimum and emphasis is given to highlight the applications of the technique.
    Type of Medium: Online Resource
    Pages: X, 72 p. 32 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030641986
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-64198-6
    DOI: 10.1007/978-3-030-64198-6
    DDC: 610.72
    Language: English
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  • 4
    Online Resource
    Online Resource
    Auxins, Cytokinins and Gibberellins Signaling in Plants (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Botanical chemistry. ; Plant physiology. ; Agriculture. ; Plant Science. ; Plant Biochemistry. ; Plant Physiology. ; Agriculture.
    Description / Table of Contents: How the three organ-produced signals: auxin, cytokinin and gibberellin, induce and regulate wood formation and adaptation -- Role of plant growth regulators in the plant-environment interaction and epigenetic regulation of auxin -- The role of auxin and cytokinin signaling components in de novo shoot organogenesis -- Mechanism of crosstalk between cytokinin and gibberellin -- In vitro responses of some Mediterranean fruit crops to auxin, cytokinin and gibberellin treatments -- Integrative approach of the root architecture by interaction between auxin and nutrients -- Insights into Biosynthesis and Signaling of Cytokinins during Plant Growth, Development and Stress Tolerance -- Cytokinin signaling in plants under salt stress -- Auxin and Cytokinin Signaling in Plant Stress Response -- Gibberellins' cross talk and signal transduction in plant stress response -- Crosstalk between Salicylic acid and Auxins, Cytokinins and Gibberellins under biotic stress -- Understanding the crosstalk between chromatin remodeling mechanism and phytohormones signaling for maintenance of plant developmental plasticity: an insight -- Phytohormone-mediated regulation of sprouting in tuber and storage root crops -- Role of phytohormones in plant-microbial interaction -- Iron toxicity tolerance in rice: roles of auxins and gibberellins -- New auxin and cytokinin related compounds based on synthetic low molecular weight heterocycles.
    Abstract: Plant hormones have pivotal roles in the regulation of plant growth, development, and reproduction. Their signaling pathways are interconnected in a complex network, which provides plants with an enormous regulatory potential to rapidly adapt to their environment and to utilize their limited resources for growth and survival in a cost-efficient manner. Auxin is a hormone molecule whose activity levels are most important for its regulatory roles during plant cell, organ, and tissue development. Therefore, the precise regulation of auxin levels is an essential mechanism to fine-tune the activity of this powerful hormone during plant growth and development. Likewise, cytokinins exhibit a wide range of physiological functions, including regulation of shoot and root apical meristems, stimulation of branching, vascular development, chloroplast differentiation, stabilization of the structure and function of the photosynthetic machinery, delay of senescence, stomata opening, and elevation of the sink strength and nutritional signaling. Moreover, gibberellins also regulate many aspects of plant growth and development including seed germination, stem elongation, leaf expansion, and flower and fruit development. The broad implication of gibberellins in plant development is strictly associated with tight regulation of their metabolism by multiple environmental and endogenous factors, ranging from light and temperature to other hormones including feedback control. Understanding the significant roles of these phytohormones in plant biology, the current subject has attracted the attention of scientists from across the globe. This comprehensive volume “Auxins, Cytokinins and Gibberellins Signaling in Plants” highlights the various prospects involved in the current scenario. The book comprises the chapters from diverse areas dealing with biotechnology, molecular biology, proteomics, genomics, metabolomics, etc.
    Type of Medium: Online Resource
    Pages: IX, 377 p. 63 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031054273
    Series Statement: Signaling and Communication in Plants,
    URL: https://doi.org/10.1007/978-3-031-05427-3
    DOI: 10.1007/978-3-031-05427-3
    DDC: 580
    Language: English
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  • 5
    Online Resource
    Online Resource
    LGBT Populations and Cancer in the Global Context (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical policy. ; Quality of life. ; Biomedical Research. ; Health Policy. ; Quality of Life Research.
    Description / Table of Contents: Foreword: Challenges & Opportunities for LGBT Populations and Cancer in Global Oncology -- Introduction -- Africa -- A Double Dose Of Stigma – Being Gay And Living With Cancer In Kenya -- Sexual Orientation, Gender Identity and Cancer in South Africa -- Americas -- Making the Situation of TLGBI People around Cancer visible: Observations from the Andean Region -- Cancer Care Challenges for the LGBT Population in Brazil -- Cancer and the SGM Population in Canada and the United States of America -- South-East Asia -- The South-East Asia Region: Societal Conditions for LGBT Health and Cancer Research -- Europe -- Foreword: The Eurocentralasian Lesbian* Community Perspective on Cancer and LBQ women: Advocating for more Research and Activism Collaboration -- LGBT+ and Cancer in the WHO European Region: Current Situation in 12 Eastern European and Central Asian Countries -- Sexual and Gender Minorities and Cancer in Germany: The Striking Absence of Understanding their Cancer-related Needs -- LGBT Populations and Cancer in the UK -- Eastern Mediterranean -- LGBT Populations and Cancer in the Eastern Mediterranean Region: Insights and Challenges with a Focus on Lebanon -- Western Pacific -- LGBT Populations and Cancer in Australia and New Zealand -- Challenges in Cancer Control Confronting the LGBT Population in China: Health Risks, Unique Barriers, and Unmet Needs -- What Have We Learned about Cancer and the Global LGBT Community? -- Index.
    Abstract: Lesbian, Gay, Bisexual, and Transgender (LGBT) also known as sexual and gender minority (SGM) populations have been the focus of global attention. Most importantly, LGBT populations have been addressed in the context of human rights in multiple reports and other activities by the United Nations and other international organizations. There is great variation among countries in the recognition of LGBT individuals’ human rights. A global focus on LGBT populations’ health is still limited, with the notable exception of HIV research. This book on LGBT populations and cancer in the global context is, therefore, an important step in that it will broaden the focus on LGBT populations’ health. Globally, cancer is the second leading cause of death. Cancer morbidity and mortality are increasing disproportionately among populations in lower-income countries. A review conducted by the World Health Organization (WHO) found that of the 82% of member states (158) countries, only 35% of the national cancer control plans addresses vulnerable population, including LGBT populations. These findings reflect an increasing awareness about equity when addressing cancer prevention and control, including LGBT populations. This book addresses LGBT populations’ cancer burden across countries that range from high- to low-income countries to support efforts in diverse countries that are working towards reducing LGBT populations’ cancer burden. It documents place-specific challenges that impede progress towards reducing the LGBT cancer burden as well as critically assesses the variation in cancer control efforts that target LGBT populations and cancer to support progress at a global scale. This book includes six sections that cover the six WHO regions, with each chapter written by an author from the specific region s/he is covering. Each chapter makes use of a template that contextualizes the region, local data collection/availability, risk factors, cancer prevention, detection, diagnosis, treatment, and survivorship.
    Type of Medium: Online Resource
    Pages: X, 335 p. 3 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065859
    URL: https://doi.org/10.1007/978-3-031-06585-9
    DOI: 10.1007/978-3-031-06585-9
    DDC: 610.72
    Language: English
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  • 6
    Online Resource
    Online Resource
    Plant Molecular Farming : Applications and New Directions (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Plant biotechnology. ; Pharmaceutical chemistry. ; Agriculture. ; Proteins . ; Plant Science. ; Plant Biotechnology. ; Pharmaceutics. ; Agriculture. ; Protein Biochemistry.
    Description / Table of Contents: Chapter. 1. Molecular Farming in Plants: Introduction and Applications -- Chapter. 2. Tools and Techniques Used in Plant Molecular Farming -- Chapter. 3. Production of plant natural products in heterologous microbial species -- Chapter. 4. Sustainable Manufacturing of Vaccines, Antibodies, and other Pharmaceuticals -- Chapter. 5. Limitations, Biosafety, ethics, regulatory issues in molecular farming in plants -- Chapter. 6. Conclusion and Perspectives.
    Abstract: Molecular farming is a biotechnological approach that includes the genetic adjustment of agricultural products to create proteins and chemicals for profitable and pharmaceutical purposes. Plant molecular farming describes the manufacture of recombinant proteins and other biologically active product in plants. This approach depends on a genetic transformation of plants that can be accomplished by the methods of stable gene transfer, such as gene transfer to nuclei and chloroplasts, and unstable transfer methods like viral vectors. The requirement for recombinant proteins in terms of quality, quantity, and diversity is increasing exponentially This demand is traditionally met by recombinant protein construction technologies and the engineering of orthodox expression systems based on bacteria or mammalian cell cultures. However, majority of developing countries cannot afford the high costs of medicine derived from such existing methods. Hence, we need to produce not only the new drugs but also the cheaper versions of those already present in the market. Plant molecular farming is considered as a cost-effective technology that has grown and advanced tremendously over the past two decades. This book summarizes the advances and challenges of plant molecular farming for all those who are working on or have an interest in this rapidly emerging area of research.
    Type of Medium: Online Resource
    Pages: IX, 77 p. 10 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031127946
    Series Statement: SpringerBriefs in Plant Science,
    URL: https://doi.org/10.1007/978-3-031-12794-6
    DOI: 10.1007/978-3-031-12794-6
    DDC: 580
    Language: English
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  • 7
    Online Resource
    Online Resource
    Progress in Botany Vol. 81 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Forestry. ; Botanical chemistry. ; Biotic communities. ; Plant genetics. ; Plant physiology. ; Plant Science. ; Forestry. ; Plant Biochemistry. ; Ecosystems. ; Plant Genetics. ; Plant Physiology.
    Description / Table of Contents: 1. Nitrogen and Sulfur Metabolism in Microalgae and Plants: 50 Years of Research -- 2. Progress Toward Deep Sequencing-Based Discovery of Stress-Related MicroRNA in Plants and Available Bioinformatics Tools -- 3. Recent Advances in MS-Based Plant Proteomics: Proteomics Data Validation Through Integration with Other Classic and -Omics Approaches -- 4. Membrane Trafficking and Plant Signaling -- 5. Molecular Aspects of Iron Nutrition in Plants -- 6. Urea in Plants: Metabolic Aspects and Ecological Implications -- 7. Biosynthesis and Regulation of Secondary Cell Wall -- 8. Stress-Induced Microspore Embryogenesis in Crop Plants: Cell Totipotency Acquisition and Embryo Development -- 9. Potential of Microalgae Biomass for the Sustainable Production of Bio-commodities -- 10. Crassulacean Acid Metabolism and Its Role in Plant Acclimatization to Abiotic Stresses and Defence Against Pathogens -- 11. The Role of the Shikimate and the Phenylpropanoid Pathways in Root-Knot Nematode Infection -- 12. Functional Diversity of Photosynthesis, Plant-Species Diversity, and Habitat Diversity -- 13. When the Tree Let Us See the Forest: Systems Biology and Natural Variation Studies in Forest Species -- 14. The Ecological Importance of Winter in Temperate, Boreal, and Arctic Ecosystems in Times of Climate.
    Abstract: With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.
    Type of Medium: Online Resource
    Pages: XIII, 399 p. 47 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030363277
    Series Statement: Progress in Botany, 81
    URL: https://doi.org/10.1007/978-3-030-36327-7
    DOI: 10.1007/978-3-030-36327-7
    DDC: 580
    Language: English
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  • 8
    Online Resource
    Online Resource
    Druggable Lipid Signaling Pathways (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Medical genetics. ; Cancer. ; Lipids. ; Biomedical Research. ; Pharmacology. ; Medical Genetics. ; Cancer Biology. ; Lipidology.
    Description / Table of Contents: Preface -- Introduction of Druggable Lipid Signaling Pathway -- Biosynthetic Enzymes of Membrane Glycerophospholipid Diversity as Therapeutic Targets for Drug Development -- Druggable Prostanoid Pathway -- Targeting Leukotrienes as a Therapeutic Strategy to Prevent Comorbidities Associated with Metabolic Stress -- Epoxy Fatty Acids are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation -- Druggable Sphingolipid Pathway -- Druggable Lysophospholipid Pathway -- Druggable targets in endocannabinoid signaling -- Drugging the phosphoinositide 3-kinase (PI3K) and phosphatidylinositol 4-kinase (PI4K) family of enzymes for treatment of cancer, immune disorders, and viral/parasitic infections -- Druggable Lipid GPCRs: Past, Present, and Prospects. .
    Abstract: This edited work presents a series of reviews focusing on Druggable Lipid Signaling Pathways. It enables researchers in both academic institutions and industry as well as physicians to understand historical aspects of lipid signaling and future directions of drug discovery targeting lipid signaling pathways. This book provides 9 pathways including acyltransferases, prostanoids, leukotrienes, epoxy fatty acids, sphingolipids, lysophospholipids, endocannabinoids, phosphoinositides, and lipid GPCRs. Readers will discover the importance of each lipid signaling pathway that contributes to broad range of diseases including neurological and neuropsychiatric diseases, pain, metabolic syndromes, cardiovascular diseases, cancer, dermatological diseases, fibrosis, inflammation, etc. Also, readers will recognize that many drugs targeting lipid signaling have been clinically used. Drugs currently under development are also discussed in each chapter, which includes some information about clinical trials and strategic drug designs. .
    Type of Medium: Online Resource
    Pages: VI, 260 p. 33 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506216
    Series Statement: Advances in Experimental Medicine and Biology, 1274
    URL: https://doi.org/10.1007/978-3-030-50621-6
    DOI: 10.1007/978-3-030-50621-6
    DDC: 610.72
    Language: English
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  • 9
    Online Resource
    Online Resource
    Essentials of Tissue and Cells Banking (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    URL: https://doi.org/10.1007/978-3-030-71621-9
    DOI: 10.1007/978-3-030-71621-9
    DDC: 610.72
    Language: English
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  • 10
    Online Resource
    Online Resource
    Mechanisms of Gene Regulation: How Science Works (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biochemistry. ; Genetics. ; Biomedical Research. ; Biochemistry. ; Genetics and Genomics.
    Description / Table of Contents: Central dogma of molecular biology -- Impact of chromatin structure -- Epigenetics enables gene expression -- Gene regulation in the context of nuclear architecture -- Core promoter -- TATA box and other core promoter elements -- Genome-wide core promoter identification -- TFIID and Mediator as paradigms of multi-protein complexes -- Site-specific transcription factors and their domains -- Classification of transcription factors -- Activation of transcription factors -- Programing cellular differentiation by transcription factors -- Inflammatory signaling via NF-KB -- Sensing cellular stress via p53 -- The nuclear receptor superfamily -- Molecular interactions of nuclear receptors -- Physiological role of nuclear receptors -- Next-generation sequencing -- Gene regulation in the context of Big Biology -- Exploring genome-wide transcription factor binding -- Integrating epigenome-wide datasets -- Cytosines and their methylation -- Histone modifications -- Gene regulation via chromatin modifiers -- Sensing energy metabolism via chromatin modifiers -- Epigenetics and chromatin -- Genome-wide understanding of epigenetics -- CTCF and genetic imprinting -- Epigenetics in health and disease -- Nucleosome positioning at promoters -- Chromatin remodeling -- Transcriptional dynamics in the presence of chromatin -- Organization of the nucleus -- Non-coding RNAs -- miRNAs and their regulatory potential -- Long ncRNAs -- Enhancer RNAs.
    Abstract: This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation.
    Type of Medium: Online Resource
    Pages: XVI, 149 p. 71 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030523213
    URL: https://doi.org/10.1007/978-3-030-52321-3
    DOI: 10.1007/978-3-030-52321-3
    DDC: 610.72
    Language: English
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  • 11
    Online Resource
    Online Resource
    Coenzyme Q in Aging (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Biochemistry. ; Physiology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Biochemistry. ; Physiology.
    Description / Table of Contents: Preface -- Part 1 Basics on coenzyme Q -- Introduction. The current coenzyme Q science and knowledge -- Molecular structure, biosynthesis, and distribution of coenzyme Q -- Coenzyme Q function in mitochondria -- Extramitochondrial coenzyme Q10 in aging -- Regulation of the synthesis of Coenzyme Q10 -- Part 2 Coenzyme Q in aging studies -- Coenzyme Q and aging in C. elegans -- Coenzyme Q and aging in the fruit fly Drosophila melanogaster -- The aging process and coenzyme Q: clk-1 mouse models -- Reduced coenzyme Q10 decelerates senescence and age-related hearing loss in senescence-accelerated mice by activating mitochondrial functions -- Part 3 Age-related diseases and coenzyme Q -- Coenzyme Q, mtDNA and mitochondrial dysfunction during aging -- Coenzyme Q10 and metabolic syndrome -- Coenzyme Q and age-related neurodegenerative disorders: Parkinson and Alzheimer diseases -- Immunosenescence and CoQ10 -- Coenzyme Q10 in fertility and reproduction -- Part 4 Prolongevity effectors and Coenzyme Q -- Calorie restriction, longevity and coenzyme Q -- Age dependent changes of coenzyme Q levels and its induction in experimental systems -- Effects of coenzyme Q10 supplementation on elderly people -- Index.
    Abstract: This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ10 is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging. The book is organized in four sections. The first offers an overview of the function of CoQ10, highlighting the two main functions of CoQ10 in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. The second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ on longevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. The final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ10 levels by induction of synthesis or by supplementation. Coenzyme Q in Aging benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process.
    Type of Medium: Online Resource
    Pages: XII, 369 p. 50 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030456429
    URL: https://doi.org/10.1007/978-3-030-45642-9
    DOI: 10.1007/978-3-030-45642-9
    DDC: 610.72
    Language: English
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  • 12
    Online Resource
    Online Resource
    A Field Guide to Tropical Plant Families (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Plant anatomy. ; Biodiversity. ; Plant Science. ; Plant Anatomy and Morphology. ; Biodiversity.
    Description / Table of Contents: Part I – User manual and architectural concepts. Chapter 1. Introduction -- Chapter 2. How to use this book 6 -- Chapter 3. Architectural concepts and key to the models -- Part II. Identification keys -- Chapter 4. Key to the groups of families of trees and shrubs (groups 1 to 52) -- Chapter 5. Keys to families of trees and shrubs -- Chapter 6. Supplementary keys -- Chapter 7. Keys to the groups of families of lianas and woody epiphytic (groups 53 to 57) -- Chapter 8. Keys to families of lianas and woody epiphytes -- PART III. Description of the families -- Chapter 9. Acanthaceae to Asteraceae -- Chapter 10. Bignoniaceae to Buxaceae -- Chapter 11. Cactaceae to Cycadaceae -- Chapter 12. Dichapetalaceae to Dipterocarpaceae -- Chapter 13. Ebenaceae to Euphorbiaceae -- Chapter 14. Fagaceae -- Chapter 15. Gentianaceae to Goupiaceae -- Chapter 16. Hamamelidaceae to Humiriaceae -- Chapter 17. Icacinaceae s.l. to Irvingiaceae -- Chapter 18. Juglandaceae -- Chapter 19. Lamiaceae to Lythraceae -- Chapter 20. Magnoliaceae to Myrtaceae -- Chapter 21. Nyctaginaceae,- Chapter 22. Ochnaceae to Oxalidaceae -- Chapter 23. Pandaceae to Putranjivaceae -- Chapter 24. Rhabdodendraceae to Rutaceae -- Chapter 25. Sabiaceae to Symplocaceae -- Chapter 26. Tetramelaceae to Torricelliaceae -- Chapter 27. Ulmaceae s.l. to Urticaceae -- Chapter 28. Verbenaceae to Vochysiaceae -- Chapter 29. Zygophyllaceae s.l -- Chapter 30. Herbaceous versus arborescent habit in the families and orders of flowering plants - evolutionary trends.
    Abstract: This book provides an identification system permitting recognition of plant families in all seasons by means of morphological and macroanatomical features which are easily observable, such as bark, exudates, stems and leaves characters. Studies of forest vegetation may differ in their underlying objectives, but they all require taxonomic knowledge. The process of taxonomy begins with an inventory of the flora, which has been based to a large extent on reproduction-related organs, such as flowers and fruits. But, those are often difficult to observe and may not exist in the field at a given time. Unlike most such guides or keys, this book can be used anywhere in the tropics and provides, in a straightforward two or three-step process, identification to the level of families, which are now circumscribed according to molecular as well as morphological characters in the universally accepted scheme of the Angiosperm Phylogeny Group. Plant architecture is not a prerequisite theme for plant identification; however, we think that an introduction to this subject is not out of place in this book (architectural traits are taxonomically sound): it is now time for botanists working in the tropics to have an idea on how the whole organism keeps growing. Within the family accounts, there is information concerning important economic plants with notes on the larger genera and, particularly helpfully, discussion of families readily confused and how to separate them. Descriptions of the families rely on short diagnosis bolstered by many photographic pictures, lines drawings and extracts from the author’s field books, all showing features of plants as they are found in the forest.
    Type of Medium: Online Resource
    Pages: XVII, 494 p. 909 illus., 850 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031059421
    URL: https://doi.org/10.1007/978-3-031-05942-1
    DOI: 10.1007/978-3-031-05942-1
    DDC: 580
    Language: English
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  • 13
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    Online Resource
    Microbiological Advancements for Higher Altitude Agro-Ecosystems & Sustainability (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Microbial ecology. ; Biotic communities. ; Agriculture. ; Industrial microbiology. ; Biomedical Research. ; Microbial Ecology. ; Ecosystems. ; Agriculture. ; Industrial Microbiology.
    Abstract: The book explores the challenges and opportunities associated with high-altitude agro-ecosystems and the factors that influence them. It discusses the various indigenous agricultural practices and approaches, as well as the microbiology of mountain & hill agro-ecosystems, providing a comprehensive overview of the various factors that control the microbiome at high altitudes. The contributions examine microbiological advances, such as use of “omics” technologies for hill agriculture and environmental sustainability, and explore the use of nanotechnology for agricultural and environmental sustainability at higher altitudes. The book also describes various aspects of low-temperature microbiology in the context of high-altitude farming and environmental sustainability.
    Type of Medium: Online Resource
    Pages: XIII, 491 p. 62 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811519024
    Series Statement: Rhizosphere Biology,
    URL: https://doi.org/10.1007/978-981-15-1902-4
    DOI: 10.1007/978-981-15-1902-4
    DDC: 610.72
    Language: English
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  • 14
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    Online Resource
    Molecular Mechanisms in Spermatogenesis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Reproductive health. ; Cytology. ; Biomedical Research. ; Reproductive Medicine. ; Cell Biology.
    Description / Table of Contents: Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases -- Ch 2: Sertoli cells: immunology and spermatogenesis -- Ch 3: Innate immunity and spermatogenesis -- Ch 4: Cell apoptosis and spermatogenesis -- Ch 5: Transcriptional regulation of spermatogenesis -- Ch 6: Sertoli cell cytoskeleton and spermatogenesis -- Ch 7: Leydig cell and spermatogenesis -- Ch 8: Cross-talk of cell junctions to support spermatogenesis -- Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis -- Ch 10: Regulation of the blood-testis barrier by basement membrane laminin-α2 chain -- Ch 11: Regulation of spermatogenesis by collagens -- Ch 12: Androgen regulation of spermatogenesis -- Ch 13: Use of molecular modeling to study spermatogenesis -- Ch 14: Acrosome biogenesis during spermatogenesis -- Ch 15: Stem cells and spermatogenesis -- Ch 16: Advances in our understanding of spermatogenesis in humans -- Ch 17: Leydig cell function in aging men -- Ch 18: Regulation of human spermatogenesis.
    Abstract: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
    Type of Medium: Online Resource
    Pages: X, 319 p. 44 illus., 40 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030777791
    Series Statement: Advances in Experimental Medicine and Biology, 1381
    URL: https://doi.org/10.1007/978-3-030-77779-1
    DOI: 10.1007/978-3-030-77779-1
    DDC: 610.72
    Language: English
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  • 15
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    Online Resource
    Biotechnological Advances in Bamboo : The “Green Gold” on the Earth (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Plant biotechnology. ; Plant cells and tissues. ; Plant Science. ; Plant Biotechnology. ; Plant Cell Biology.
    Description / Table of Contents: Bamboo: origin, habitat, distributions and global prospective -- Molecular markers in bamboos: understanding reproductive biology, genetic structure, interspecies diversity and clonal fidelity for conservation and breeding -- Standard protocols for in vitro propagation of bamboo with emphasis on axillary shoot proliferation -- Somatic embryogenesis in bamboos: advances and prospects -- Initiation and establishment of cell suspension culture in bamboo -- Micro-morpho-anatomical alterations in micropropagated plants of endrocalamus strictus -- Micropropagation of bamboos and clonal fidelity assessment using molecular markers -- Standardization of laboratory to land transfer strategies of micropropagated plantlets of bamboo -- Management of bamboo genetic resources and clonal production systems -- Polymorphism and phylogenetic relationships in bamboo -- Transgenics approaches in Bamboo -- Advances in Conservation of Bamboo Genetic Resources through Whole Seeds Cryopreservation -- Application of Biotechnological Tool in Bamboo Improvement -- Ethnobamboology: traditional uses of bamboos and opportunities to exploit genomic resources for better exploitation -- Bamboo flowering in South America: what the past tells about the future -- Molecular Markers in Bamboo Genotyping: Prospects for Conservation and Breeding -- Application of bamboo in the food and pharmaceutical industry -- Functional pasta: a comparative study of the use of bamboo shoot fiber and white fibers -- Bamboo fiber as a substitute for fat and/or sugar in cookies -- Practical application of bamboo as a building material: trends and challenges.
    Abstract: “Green gold” or “Poor Man’s Timber” are commonly used terms for bamboo that is a valuable and renewable resource of the world, and has always been an elemental part of human beings in terms of social and economic value. Bamboo is considered a multipurpose plant and has a prolonged history as an adaptable and extensively used renewable resource in conventional and commercial applications. Therefore, the annual demands for bamboos have already out-crossed the annual yields across the world. And the current scenario has forced scientists to pay more attention to the utilization of biotechnological tools for better understanding and improving bamboos. The book provides an overview of the different biotechnological approaches to advance bamboo research and better utilization of bamboo resources for human beings. Various applications of biological techniques in relation to bamboo have been discussed in details, for example, plant tissue culture techniques, somatic embryogenesis, germplasm conservation techniques, use of the molecular markers, transcriptomics, polymorphism, and phylogenetic relations in bamboo. It also addresses the novel industrial applications of bamboo in structural, food, and pharmaceuticals along with traditional uses. The aggregated information in this book demonstrates the way for the improved and sustainable practice of bamboos to fulfill the future needs of the world. This book is intended for use in both the industry and academia.
    Type of Medium: Online Resource
    Pages: XV, 481 p. 82 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811613104
    URL: https://doi.org/10.1007/978-981-16-1310-4
    DOI: 10.1007/978-981-16-1310-4
    DDC: 580
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  • 16
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    Online Resource
    The Renin Angiotensin System in Cardiovascular Disease (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cardiovascular system. ; Physiology. ; Cardiology. ; Clinical biochemistry. ; Biomedical Research. ; Cardiovascular Physiology. ; Cardiology. ; Medical Biochemistry.
    Description / Table of Contents: Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure.
    Abstract: This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.
    Type of Medium: Online Resource
    Pages: XVIII, 452 p. 71 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031149528
    Series Statement: Advances in Biochemistry in Health and Disease, 24
    URL: https://doi.org/10.1007/978-3-031-14952-8
    DOI: 10.1007/978-3-031-14952-8
    DDC: 610.72
    Language: English
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  • 17
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    Online Resource
    Plant Metal and Metalloid Transporters (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Agriculture. ; Plant molecular biology. ; Botanical chemistry. ; Plant Science. ; Agriculture. ; Plant Molecular Biology. ; Plant Biochemistry.
    Description / Table of Contents: Chapter 1. Plant Metal and Metalloid Transport -- Chapter 2. Heavy Metals: Transport in Plants and their Physiological and Toxicological Effects -- Chapter 3. The Role of ABC Transporter in Metal Tranasport in Plants -- Chapter 4. Cadmium, A Non-Essential Heavy Metal: Uptake, Translocation, Signaling, Detoxification, and Impact on Amino Acid Metabolism -- Chapter 5. Natural Resistance Associated Macrophage Proteins (NRAMP): Functional Significant of Metal Transport in Plants -- Chapter 6. Role of Heavy Metal Atpases in Transport of Cadmium and Zinc in Plants -- Chapter 7. The Versatile Role of Plant Aquaglyceroporins in Metalloid Transport -- Chapter 8. The Multidrug and Toxic Compound Extrusion (MATE) Family in Plants and Their Significance in Metal Transport -- Chapter 9. Molecular Mechanism of Aluminium Tolerance in Plants: An Overview -- Chapter 10. Functional, Structural, and Transport Aspects of ZIP in Plant -- Chapter 11. The Function of HAK as K+ Transporter and AKT as Inward Rectifying Agent in The K+ Channel -- Chapter 12. The Mechanism of Silicon Transport in Plants -- Chapter 13. The Copper Transport Mechanism in Plants -- Chapter 14. Plant Metal Tolerance Proteins: Insight Into their Roles in Metal Transport and Homeostasis for Future Biotechnological Applications -- Chapter 15. Co-Transport Mechanism in Plants for Metals and Metalloids -- Chapter 16. Metal Nanoparticles Implication, Transport, and Detection in Plants -- Chapter 17. Transcription Factors and Metal Stress Signalling in Plants -- Chapter 18. Heavy Metal Transporters, Phytoremediation Potential and Biofortification -- Chapter 19. Phytoremediation and Biofortification: Contrasting Yet Similar Approaches of Manipulating Plant Metal(Loid) Homeostasis for Societal Benefit.
    Abstract: This edited book stands as a one place knowledge hub for plant metal(loid) transporters. The book comprehensively covers holistic aspect of metal(loid) transporters involved in uptake and translocation of essential as well as toxic metal(loid)s. Essential and beneficial metal(loid)s are required in every biological process for normal plant growth and development, however in excess they are toxic. There are toxic metal(loid)s also whose accumulation in plants interferes with normal cellular functioning and hampers growth of plants. Hence, metal(loid) uptake and accumulation in plants is a highly regulated phenomenon involving the role of several transporters, enzymes, metabolites, transcription factors and post translational modifications. The book contains chapters from the experts and the contents of the book are presented in simple language and represented through beautiful and scientifically informative figures and tables. This book is of interest to teachers, researchers, doctoral and graduate students working in the area of plant physiology, environmental biotechnology, plant biotechnology metal(loid) stress, phytoremediation and crop biofortification.
    Type of Medium: Online Resource
    Pages: XIII, 454 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811961038
    URL: https://doi.org/10.1007/978-981-19-6103-8
    DOI: 10.1007/978-981-19-6103-8
    DDC: 580
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  • 18
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    Online Resource
    Molecular Mechanisms of Retina Pathology and Ways of its Correction (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cytology. ; Pharmacy. ; Biomedical Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cell Biology. ; Pharmacy.
    Description / Table of Contents: Chapter 1. Literature review -- Chapter 2. Results of experimental studies of short peptides (cytogens) in ophthalmology -- Chapter 3. Results of the clinical study of short peptides (cytogens) in ophthalmology -- Conclusion.
    Abstract: This book discusses the pathology of the retina, and reviews current research on the use of cell replacement therapy and short peptides to restore functional activity in retinal neurons. As the book describes, pathologies of the retina, including age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, present a long-standing challenge in the practice of clinical ophthalmology. Modern treatment for these conditions, which lead to irreversible blindness, includes laser exposure, surgical intervention, and drugs. These treatments aim to reduce the risk of new complications in the eye; pathogenetic therapy of degenerative diseases of the retina is practically absent in current ophthalmic practice. The first section of the book reviews the molecular mechanisms of age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, and reports on methods of treatment. The second section presents the results of recent experimental studies of the effects of short peptides on pluripotent embryonic cells; on proliferative activity in retinal cells and pigment epithelium; on expression of markers of differentiation or retinal neurons and pigment epithelium; and on the course of hereditary retinal pigmentation in Campbell rats. The third section offers results of clinical studies on the effectiveness of short peptides in patients with macular degeneration, and in patients with retinitis pigmentosa. The author concludes that the regular use of peptides in the treatment of degenerative diseases of the retina can slow the progression of the pathological process and preserve the patient’s vision for some 10-15 years. In addition, in 80 percent of patients, it is possible to increase visual function by increasing visual acuity, improving the boundaries of the visual field and the fundus.
    Type of Medium: Online Resource
    Pages: VI, 90 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030501600
    URL: https://doi.org/10.1007/978-3-030-50160-0
    DOI: 10.1007/978-3-030-50160-0
    DDC: 610.72
    Language: English
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  • 19
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    Online Resource
    Autophagy: Biology and Diseases : Clinical Science (2020)
    Singapore :Springer Nature Singapore :
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    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Medical sciences. ; Pharmacology. ; Biomedical Research. ; Cell Biology. ; Health Sciences. ; Pharmacology.
    Description / Table of Contents: Autophagy and Alzheimer’s Disease -- Autophagy and Parkinson’s Disease -- Autophagy and Motor Neuron Diseases -- Autophagy and Prion Disease -- Autophagy and Lysosome Storage Disorders -- Autophagy and Mitochondrial Encephalomyopathies -- Autophagy and Ischemic Stroke -- Autophagy and Hemorrhagic Stroke -- Autophagy and Polyglutamine Disease -- Autophagy and Epilepsy -- Autophagy in Neurodevelopmental Disorders -- Autophagy and Pituitary Adenoma -- Autophagy in Schizophrenia -- Autophagy and Hypertension -- Autophagy and Myocardial Ischemia -- Autophagy and Heart Failure -- Autophagy, Myocarditis and Cardiomyopathy -- Autophagy, Hyperlipidemia and Atherosclerosis -- Application of Autophagy in Cardiovascular Diseases -- Autophagy and Tumorigenesis -- Autophagy and Tumour Stem Cells -- Autophagy and Tumour Metastasis -- Autophagy and Tumor Cell Death -- Autophagy and Tumour Chemotherapy -- Autophagy and Tumour Radiotherapy -- Autophagy and Inflammatory Diseases -- Autophagy and Immune-related Diseases -- Autophagy and Autoimmune Diseases -- Autophagy and Bacterial Infection -- Autophagy and Viral Infection -- Autophagy and Thyroid Disease -- Autophagy and Obesity and Diabetes -- Autophagy and Obesity-related Reproductive Dysfunction -- Autophagy and Acute Kidney Injury -- Autophagy and Glomerular Diseases -- Autophagy and Diabetic Nephropathy -- Autophagy and Liver Diseases -- Autophagy and Gastrointestinal Diseases -- Chronic Obstructive Pulmonary Disease and Autophagy -- Autophagy and Pulmonary Fibrosis -- Asthma and Autophagy -- Autophagy and Other respiratory diseases -- Autophagy and Leukemia -- Autophagy and Lymphoma -- Autophagy and Myeloma -- The Function and Mechanisms of Autophagy in Traumatic Brain Injury -- The Function and Mechanisms of Autophagy in Spinal Cord Injury -- The Function and Mechanisms of Autophagy in Trauma of Other Parts of the Body -- The Prospects of Therapeutic Potential and Drug Development Targeting Autophagy in Cancer -- Progress of Anti-aging Drugs Targeting Autophagy -- Drug Development and Treatment of Autophagy in Other Diseases -- Systems Biology Approaches in Autophagy Research -- Natural Product Regulates Autophagy in Cancer -- Regulation of Autophagy in Neurodegenerative Diseases by Natural Products -- Regulation of Autophagy in Cardiovascular Diseases by Natural Products.
    Abstract: This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine.
    Type of Medium: Online Resource
    Pages: XXXVI, 736 p. 50 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811542725
    Series Statement: Advances in Experimental Medicine and Biology, 1207
    URL: https://doi.org/10.1007/978-981-15-4272-5
    DOI: 10.1007/978-981-15-4272-5
    DDC: 610.72
    Language: English
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  • 20
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    Online Resource
    Explaining Health Across the Sciences (2020)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Medicine Philosophy. ; Medical sciences. ; Science Philosophy. ; Biomedical Research. ; Philosophy of Medicine. ; Health Sciences. ; Philosophy of Science.
    Abstract: This edited volume aims to better understand the multifaceted phenomenon we call health. Going beyond simple views of health as the absence of disease or as complete well-being, this book unites scientists and philosophers. The contributions clarify the links between health and adaptation, robustness, resilience, or dynamic homeostasis, and discuss how to achieve health and healthy aging through practices such as hormesis. The book is divided into three parts and a conclusion: the first part explains health from within specific disciplines, the second part explores health from the perspective of a bodily part, system, function, or even the environment in which organisms live, and the final part looks at more clinical or practical perspectives. It thereby gathers, across 30 chapters, diverse perspectives from the broad fields of evolutionary and systems biology, immunology, and biogerontology, more specific areas such as odontology, cardiology, neurology, and public health, as well as philosophical reflections on mental health, sexuality, authenticity and medical theories. The overarching aim is to inform, inspire and encourage intellectuals from various disciplines to assess whether explanations in these disparate fields and across biological levels can be sufficiently systematized and unified to clarify the complexity of health. It will be particularly useful for medical graduates, philosophy graduates and research professionals in the life sciences and general medicine, as well as for upper-level graduate philosophy of science students.
    Type of Medium: Online Resource
    Pages: XVII, 555 p. 30 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030526634
    Series Statement: Healthy Ageing and Longevity, 12
    URL: https://doi.org/10.1007/978-3-030-52663-4
    DOI: 10.1007/978-3-030-52663-4
    DDC: 610.72
    Language: English
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  • 21
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    Online Resource
    The Geography of Black Pepper (Piper nigrum) : The "King" of Spices – Volume 1 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Food science. ; Plant ecology. ; Economic geography. ; Agriculture. ; Plant Science. ; Food Science. ; Plant Ecology. ; Economic Geography. ; Agriculture.
    Description / Table of Contents: Preface -- Chapter 1 Introduction -- Chapter 2 The Pepper Plant—Its Botany and Chemistry -- Chapter 3 Pepper Agronomy -- Chapter 4 The Role of the Nutrient Buffer Power Concept in Pepper Nutrition -- Chapter 5 Establishing a Pepper Plantation -- Chapter 6 Pepper Pests and Their Control -- Chapter 7 The Processing of Black Pepper on Farm -- Chapter 8 An Account of Indonesian Pepper Processing -- Chapter 9 Industrial Processing of Black Pepper -- Chapter 10 The Future of the Global Pepper Economy -- Chapter 11 Pepper Economy in India -- Chapter 12 Pepper Pharmacopoeia -- Chapter 13 Consumer Products Out of Black Pepper -- Chapter 14 Value Addition in Pepper -- Chapter 15 Conclusions and a Peep Into Pepper’s Future -- PRECISE QUANTIFICATION OF PLANT NUTRIENT BIO AVAILABILITY FOR BLACK PEPPER AND CARDAMOM -- TECHNOLOGICAL INNOVATIONS IN SPICES RESEARCH AND DEVELOPMENT!!!.
    Abstract: This book considers all aspects of black pepper from its growth, as a flowering vine, to how the dried fruit (peppercorn) is used as a spice and traded as a commodity. It is the economic mainstay of several India states and, principally, in Kerala State, with the Indian subcontinent being the largest black pepper producer. Indonesia has also emerged as a large producer of black pepper. Black pepper commands a leading position among the spices and has an immense commercial importance to world trade, finding its way onto the dining table of millions around the world, on the European and North American continents, and Japan. The use of black pepper ranges from a simple dietary component and flavour enhancer, to that of a spice with huge pharmacological benefits. .
    Type of Medium: Online Resource
    Pages: XIV, 162 p. 24 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030528652
    URL: https://doi.org/10.1007/978-3-030-52865-2
    DOI: 10.1007/978-3-030-52865-2
    DDC: 580
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  • 22
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    Online Resource
    Wetland Plants : A Source of Nutrition and Ethno-medicines (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Nutrition   . ; Medicinal chemistry. ; Food science. ; Plant Science. ; Nutrition. ; Medicinal Chemistry. ; Food Science.
    Description / Table of Contents: Foreword -- Preface -- Wetlands and Wetland Plants -- Climate of Wetlands -- Types of Wetlands and Wetland Plants -- Importance of Biodiversity in Wetlands -- Nutritive Value of Wetland Flora -- Medicinally Important Wetland Flora -- Threats to Biodiversity of Wetlands -- Conservation Strategies of Wetland Flora -- Wetland Plants of Himalayas: A case study -- A Pictorial Guide to Wetland plants of Himalayas -- Bibliography.
    Abstract: Due to their high nutritive value and the presence of secondary metabolites, wetland plants can be consumed by humans as food and utilized as medicinal drugs. Significant numbers of ethno-botanic resources have been reported to extract useful compounds, which can be used as pharmaceuticals. Wetland plants are also very valuable as an energy source, as fuel for fish smoking and for domestic energy. These plants can be harvested as wild stock, or cultivated in flooded paddies for aquaculture, food and for livestock fodder. All parts of plants can be utilized for foodstuff, compost, mulch, medicine, and for construction. Wetland Plants: A Source of Nutrition and Ethnomedicine aims to promote public understanding of this remarkable resource, exploring not only their role in the ecosystem but also their nutritional and medicinal purposes. Based on original research, the text focuses on species identification (with original pictures of wetland plants including morphological features), nutritive value and ethno-medicinal uses. This book serves as an important and basic reference material for further research into the basic biological as well as the applied medicinal aspects of traditional medicinal wetland plants.
    Type of Medium: Online Resource
    Pages: XXIX, 228 p. 149 illus., 148 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030692582
    URL: https://doi.org/10.1007/978-3-030-69258-2
    DOI: 10.1007/978-3-030-69258-2
    DDC: 580
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  • 23
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    Online Resource
    Genome Editing in Cardiovascular and Metabolic Diseases (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Metabolism Disorders. ; Genetics. ; Cardiovascular system. ; Physiology. ; Biomedical Research. ; Metabolic Disease. ; Genetics and Genomics. ; Cardiovascular Physiology.
    Description / Table of Contents: An overview of genome editing in cardiovascular and metabolic diseases -- Bioinformatics research methodology of genome editing in cardiovascular and metabolic diseases -- Online databases of genome editing in cardiovascular and metabolic diseases -- Application of systems biology for genome editing involved in regulating of cardiovascular and metabolic diseases -- Bioinformatics for reducing off-targets in cardiovascular and metabolic diseases -- Genome editing and cardiac regeneration -- Genome editing and myocardial development -- Genome editing and heart failure -- Genome editing and pathological cardiac hypertrophy -- Genome editing and cardiac remodeling -- Genome editing and diabetic cardiomyopathy -- Genome editing and cardiac arrhythmias -- Genome editing and atrial fibrillation -- Genome editing and muscle atrophy -- Genome editing and obesity -- Genome editing and fatty liver -- Genome editing and diabetes -- Genome editing and gout -- Genome editing and protein energy malnutrition -- Genome therapy and cardiovascular diseases -- Therapeutics in metabolic diseases -- Gene editing and human iPSCs in cardiovascular and editing diseases -- Prospective advances in genome editing investigation.
    Abstract: This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.
    Type of Medium: Online Resource
    Pages: XII, 339 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811956423
    Series Statement: Advances in Experimental Medicine and Biology, 1396
    URL: https://doi.org/10.1007/978-981-19-5642-3
    DOI: 10.1007/978-981-19-5642-3
    DDC: 610.72
    Language: English
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  • 24
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    Online Resource
    Medicinal Plants of the Asteraceae Family : Traditional Uses, Phytochemistry and Pharmacological Activities (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Biochemistry. ; Plant Science. ; Chemical Biology.
    Description / Table of Contents: Chapter 1. An overview of medicinal plants of the Asteraceae family and their impact on human health -- Chapter 2. Artemisia annua L.: Traditional uses, Phytochemistry and Pharmacological activities -- Chapter 3. Artemisia indica Wild.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 4. Arnica montana L.: Traditional uses, bioactive chemical constituents, and pharmacological activities -- Chapter 5. Aster tataricus L.f.: Ethnomedicinal uses, phytochemistry and pharmacological activities -- Chapter 6.Atractylodes lancea (Thunb.) DC.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 7. Carthamus tinctorius L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 8.Chrysanthemum morifolium Ramat.: A Medicinal Plant with Diverse Traditional Uses, Bioactive Constituents, and Pharmacological Activities -- Chapter 9.Crassocephalum crepidioides (Benth.) S.Moore: Traditional uses, chemical constituents and biological activities -- Chapter 10. Dolomiaea costus (Falc.) Kasana & A. K. Pandey: Ethnomedicinal uses, bioactive chemical constituents and Pharmacological activities -- Chapter 11.Eclipta prostata (L.) L.: Traditional use, phytochemistry and pharmacology -- Chapter 12. Helianthus annuus L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 13. Silybum marianum (L.) Gaertn.: Traditional uses, phytochemistry and pharmacological activities.
    Abstract: This book highlights 12 major plants in the Asteraceae family from the aspects of traditional uses as food and medicine, phytochemistry, and pharmacological activities. Asteraceae is one of the largest family of flowering plants comprising over 1,600 plant genera and 32,000 plant species. Plants belonging to this family have a long history of being used as medicinal plants for the treatment of various diseases. Many of them are also used in the preparation of foods, beverages, and also used in pharmaceutical and cosmetic industries. In addition, plants such as Artemisia annua have played an important role in the discovery of novel drugs. The book summarizes the traditional uses of the plants in the family Asteraceae and their scientific validation, which helps readers understand their relation and impact on human health. It also explains the Phytochemistry of the species and presents the pharmacological activities and mechanisms in detail. Understanding current scientific knowledge will help in the commercialization of products based on these plants and also helps to find the research gaps that should be fulfilled in the future for their optimal use. It also helps in increasing the awareness of the plant species related to conservation, cultivation, and sustainable utilization. This edited volume comprises chapters contributed by experts from around the world. .
    Type of Medium: Online Resource
    Pages: IX, 230 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811960802
    URL: https://doi.org/10.1007/978-981-19-6080-2
    DOI: 10.1007/978-981-19-6080-2
    DDC: 580
    Language: English
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  • 25
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    Online Resource
    Salivary Bioscience : Foundations of Interdisciplinary Saliva Research and Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Biochemistry. ; Psychology. ; Dentistry. ; Endocrinology. ; Biomedical Research. ; Medical Biochemistry. ; Biochemistry. ; Behavioral Sciences and Psychology. ; Dentistry. ; Endocrinology.
    Description / Table of Contents: Part 1: What is Salivary Bioscience, Why is it Important, and How Do We Study It? -- Chapter 1: Foundations of Interdisciplinary Salivary Bioscience: An Introduction (Granger et al.) -- Chapter 2: Salivary Gland Anatomy and Physiology (Hernández et al.) -- Chapter 3: Saliva Collection, Handing, Transport, and Storage: Special Considerations and Best Practices for Interdisciplinary Salivary Bioscience(Padilla et al.) -- Chapter 4: Analytical Strategies and Tactics in Salivary Bioscience (Riis et al.) -- Part 2: Physiology and Development Research and Applications (Part 2 Editor: Dr. Jenna Riis) -- Chapter 5: Salivary Bioscience, Human Stress, and the Hypothalamic Pituitary Adrenal Axis (Clow et al.) -- Chapter 6: The Use of Saliva for Genetics and Epigenetics Research (Nemoda et al.) -- Chapter 7: Saliva as a Window Into the Human Oral Microbiome and Metabolome(Whiteson et al.) -- Chapter 8: Salivaomics, saliva Exo-somics, and Saliva Liquid Biopsy (Wong et al.) -- Chapter 9: Salivary Bioscience, Immunity, and Inflammation (Riis et al.) -- Chapter 10:Salivary Bioscience and Human Development (Hibel et al.) -- Part 3: Biomedical Research and Related Applications (Part 3 Editor: Dr. Elizabeth Thomas) -- Chapter 11: Biomedical Research and Related Applications:Current Assay Methods and Quality Requirements in Oral Fluid Diagnostics Applications (Granger S. et al.) -- Chapter 12: Salivary Biomarkers and Neurodegenerative Conditions (Thomas et al.) -- Chapter 13: The Use of Antibodies in Saliva to Measure PathogenExposure and Infection(Heaney et al.) -- Chapter 14: Salivary Bioscience and Pain (Payne et al.) -- Chapter 15: Salivary Bioscience and Environmental Exposure Assessment (Panuwet et al.) -- Chapter 16: Saliva and Drugs of Abuse (Navazesh et al.) -- Chapter 17: Therapeutic Drug Monitoring in Saliva (Thomas) -- Chapter 18: Salivary Bioscience and Periodontal Medicine (Freire et al.) -- Chapter 19: Salivary Bioscience and Cancer (Navazesh et al.) -- Part 4: Psychosocial Research and Applications(Part 4 Editor: Dr. Kate Ryan Kuhlman) -- Chapter 20: Salivary Bioscience in Clinical Psychologyand Psychiatry(Kuhlman) -- Chapter 21: Salivary Bioscience Research in Health Psychology and Behavioral Medicine (Hoyt et al.) -- chapter 22: The Neuroscience of Human Social Behavior: A Review of How Testosterone and Cortisol Underpin Competition and Affiliation Dynamics (Kornienko et al.) -- chapter 23: Salivary Studies of the Social Neuroscience of Human-animal Interaction (Pendry et al.) -- Part 5: Population Health Research and Applications(Part 5 Editor: Dr. Marcus Taylor) -- Chapter 24: Salivary Bioscience and Military, Space, and OperationalResearch(Roma et al.) -- Chapter 25: Salivary Bioscience Research Related to Prenatal Adversity (Eiden et al.) -- Chapter 26: Salivary Bioscience and Pediatrics (Johnson et al.) -- Chapter 27: Use of saliva to better understand the experience of adulthood and aging(Almeida et al.) -- Chapter 28: Salivary Bioscience and Research on Animal Welfare and Conservation Science(Staley et al.) -- Part 6: The Way Forward: Future Directions for the Science and Practice of Salivary Bioscience -- Chapter 29:Applications of Salivary Bioscience to Precision Medicine (Kuhlman) -- Chapter 30:Public Health and IndustryApplications of Salivary Bioscience (Riis et al.) -- Chapter 31: Envisioning the Future of Interdisciplinary Salivary Bioscience (Granger et al.).
    Abstract: This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice.
    Type of Medium: Online Resource
    Pages: XIV, 751 p. 56 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357849
    URL: https://doi.org/10.1007/978-3-030-35784-9
    DOI: 10.1007/978-3-030-35784-9
    DDC: 610.72
    Language: English
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  • 26
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    Online Resource
    Periodontitis : Advances in Experimental Research (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Parasitology. ; Biomedical Research. ; Medical Microbiology. ; Parasitology.
    Description / Table of Contents: Preface -- Chapter1. Advances in experimental research about periodontitis: lessons from the past, ideas for the future (Julien Santi-Rocca) -- Part I: Periodontal microbiota -- Chapter 2. Microbiota in Periodontitis: advances in the omic era (Shao Bing Fong, Emile Boyer, Martine Bonnaure-Mallet, Vincent Meuric) -- Chapter 3. Aggregatibacter actinomycetemcomitans: from basic to advanced research (Abdelhadi Hbibi, Amal Bouziane, Badiaa Lyoussi, Mimoun Zouhdi, Driss Benazza) -- Chapter 4. Meta-analyses on the Periodontal Archaeome (Jéssica Alves de Cena, Yuri Silvestre-Barbosa, Aline Belmok, Cristine Miron Stefani, Cynthia Maria Kyaw, Nailê Damé-Teixeira) -- Chapter 5. Parasites in periodontal health and disease: a systematic review and meta-analysis (David Felipe Martin-Garcia, Malik Sallam, Gabriela Garcia, Julien Santi-Rocca) -- Chapter 6. Fungi - a component of the oral microbiome involved in periodontal diseases (Justyna Karkowska-Kuleta, Dorota Satala, Magdalena Smolarz, Marcin Zawrotniak, Maria Rapala-Kozik) -- Chapter 7. Herpesviruses in periodontitis: An umbrella review (Aleksandar Jakovljevic, Miroslav Andric, Jelena Jacimovic, Jelena Milasin, Javier Enrique Botero) -- Part II: Periodontitis pathophysiology -- Chapter 8. Recent updates on microbial biofilms in periodontitis: an analysis of in vitro biofilm models (Maick Meneguzzo Prado, Nathalia Figueiredo, Andréa Pimenta, Tamires Szeremeske Miranda, Magda Feres, Luciene Cristina Figueiredo, Josiane de Almeida, Bruno Bueno-Silva) -- Chapter 9. Update on B cell response in periodontitis (Julien Demoersman, Jacques Olivier Pers) -- Chapter 10. Polarization profiles of T lymphocytes and macrophages responses in periodontitis (Franco Cavalla, Marcela Hernández) -- Chapter 11. Complementary experimental methods in genetics open up new avenues of research to elucidate the pathogenesis of periodontitis (Arne S. Schaefer) -- Part III: Periodontitis-associated conditions -- Chapter 12. Update on the bidirectional link between diabetes and periodontitis (Leila Salhi, Michèle Reners) -- Chapter 13. Periodontitis as a risk factor for Alzheimer’s disease: the experimental journey so far, with hope of therapy (Alice Harding, Shalini Kanagasingam, Richard Welbury, Sim K. Singhrao) -- Chapter 14. Cardiovascular diseases and periodontitis (Peter Riis Hansen, Palle Holmstrup) -- Part IV: Therapeutic management of periodontitis -- Chapter 15. Update on the role of cytokines as oral biomarkers in the diagnosis of periodontitis (Triana Blanco-Pintos, Alba Regueira-Iglesias, Carlos Balsa-Castro, Inmaculada Tomás) -- Chapter 16. Non-surgical periodontal treatment: SRP and innovative therapeutic approaches (Alexia Vinel, Antoine Al Halabi, Sébastien Roumi, Hélène Le Neindre, Pierre Millavet, Marion Simon, Constance Cuny, Jean-Sébastien Barthet, Pierre Barthet, Sara Laurencin-Dalicieux) -- Chapter 17. Update on the roles of oral hygiene and plaque control on periodontal disease (Leila Salhi, Bruno De Carvalho, Michèle Reners) -- Chapter 18. Multi-photonic adjunctive therapy for the management of periodontitis: recent advances and new treatment approach (Marco Giannelli, Daniele Bani) -- Chapter 19. Probiotics during the therapeutic management of periodontitis (Flavia Furlaneto, Karin Hitomi Ishikawa, Michel Reis Messora, Marcia P A Mayer) -- Chapter 20. Periodontal cell therapy: a systematic review and meta-analysis (Antoine Dubuc, Valérie Planat-Bénard, Mathieu Marty, Paul Monsarrat, Philippe Kémoun) -- Index.
    Abstract: Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendations for health professionals. A better information of the empowered patients, leading them to consider prevention and to take part in their therapeutic course. The book “Periodontitis: Advances in Experimental Research” includes a timely collection of chapters covering all the fields of research about periodontitis, consisting in concise reviews by the best specialists themselves and with clinical perspectives for periodontitis. Recent technological advances have allowed to explore shadowed areas of periodontology. The book “Periodontitis: Advances in Experimental Research” is a unique occasion to set a milestone for a more integrated field of periodontitis, with a broad scientific, medical, and public audience thanks to dedicated sections in each chapter: Abstract and main body (scientific audience and expert clinicians) Highlights (scientific audience and clinicians) Impact for Practice (clinicians and economical/political decision makers) Summary for Patients (patients and economical/political decision makers).
    Type of Medium: Online Resource
    Pages: XIII, 402 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968816
    Series Statement: Advances in Experimental Medicine and Biology, 1373
    URL: https://doi.org/10.1007/978-3-030-96881-6
    DOI: 10.1007/978-3-030-96881-6
    DDC: 610.72
    Language: English
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    Online Resource
    Biomedical Translational Research : Technologies for Improving Healthcare (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cancer. ; Technology Sociological aspects. ; Genomics. ; Biomedical Research. ; Cancer Biology. ; Emerging Technologies. ; Genomics.
    Description / Table of Contents: Chapter 1. Introduction to emerging technologies in biomedical sciences -- Chapter 2. Bioprospecting : boon or curse -- Chapter 3. Growing need for interdisciplinary biomedical research -- Chapter 4. Interplay between theory and experiment : a future approach for biomedical research -- Chapter 5.past, present and future perspectives of biomedical innovation in india -- Chapter 6. Systems biology approaches to study disease comorbidities -- Chapter 7. Bioinformatics the interactome of multidisciplinary approaches -- Chapter 8. Role of artificial intelligence in diagnosis of infectious diseases -- Chapter 9. Dna digital data storage breakthroughs in biomedical research. Chapter 10. Biomedical applications cloud-based iot -- Chapter 11. Next generation sequencing in cancer research -- Chapter 12. Crispr: genome editing and beyond -- Chapter 13. Omics in tuberculosis diagnosis : today and tomorrow -- Chapter 14. Advances in proteomic approaches for chronic kidney disease -- Chapter 15. 3 d bioprinting of tissues and organs : a new paradigm in regenerative medicine and biomedical engineering -- Chapter 16. Virtual planning, rapid prototyping and 3-d printing in orthopedic surgery -- Chapter 17. Tissue chips: contemporary applications and advancementstissue chips: contemporary applications and advancements -- Chapter 18. Flow cytometry for measuring neutrophil function -- Chapter 19. Flow cytometer for understanding genome size variation among medicinal herbs and non-edible oil trees of northeast india -- Chapter 20. Raman spectroscopy applications for bacterial detection -- Chapter 21. Microfluidic point-of-care diagnostic devices: a contemporary relevance. Chapter 22. Fluorescent dots for breast cancer management -- Chapter 23. Molecular mimicry : unravelling the role of autoantibodies in autoimmune diseases and infertility -- Chapter 24. Strategies of vaccine development -- Chapter 25. Preclinical models of intimal hyperplasia and restenosis to predict clinical events and develop novel therapies -- Chapter 26. Sphingolipids : a roadmap from biomarker identification to clinical application -- Chapter 27. Future of gastrointestinal endoscopy -- Chapter 28. Beating heart in a box : the future of cardiac transplant -- Chapter 29. The journey of coronary stent technology -- Chapter 30. Materiovigilance in clinical surgery.
    Abstract: This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.
    Type of Medium: Online Resource
    Pages: XIII, 505 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643453
    URL: https://doi.org/10.1007/978-981-16-4345-3
    DOI: 10.1007/978-981-16-4345-3
    DDC: 610.72
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  • 28
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    Online Resource
    Microbes and Oral Squamous Cell Carcinoma : A Network Spanning Infection and Inflammation (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Microbial genetics. ; Industrial microbiology. ; Microbiology. ; Biomedical Research. ; Medical Microbiology. ; Microbial Genetics. ; Industrial Microbiology. ; Microbiology.
    Description / Table of Contents: Chapter 1. Epidemiology of Oral Squamous Cell Carcinoma in Indian Scenario -- Chapter 2. Risk factors for Oral Squamous Cell Carcinoma in the Indian population -- Chapter 3. Molecular Carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 4. Inflammation and Infection in Cancer -- Chapter 5. Role of Inflammation and Infection in Oral Squamous Cell Carcinoma -- Chapter 6. Normal Microbiome of Oral cavity -- Chapter 7. Oral Microbiome in Oral Squamous Cell Carcinoma -- Chapter 8. Microbial Dysbiosis in Oral Squamous Cell Carcinoma -- Chapter 9. Bacteria induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 10. Virus induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 11. Fungi: Culprits or Bystanders in Oral Squamous Cell Carcinoma -- Chapter 12. Microbial ‘omics’ in Oral Squamous Cell Carcinoma -- Chapter 13. Implications and Future perspectives.
    Abstract: This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention. The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like for this area of research. The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.
    Type of Medium: Online Resource
    Pages: XIII, 172 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811905926
    URL: https://doi.org/10.1007/978-981-19-0592-6
    DOI: 10.1007/978-981-19-0592-6
    DDC: 610.72
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  • 29
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    Online Resource
    Biomedical Visualisation : Volume 14 ‒ COVID-19 Technology and Visualisation Adaptations for Biomedical Teaching (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical education. ; Anatomy. ; Virtual reality. ; Augmented reality. ; Biomedical Research. ; Medical Education. ; Anatomy. ; Virtual and Augmented Reality.
    Description / Table of Contents: Chapter 1. Pandemic-Era Digital Education: Insights from an Undergraduate Medical Programme -- Chapter 2. Use of Lt Systems in Large Class Lab Delivery -- Chapter 3. COVID-19 Adaptations for Biomedical Teaching and Assessment Within the Undergraduate Dental Curriculum -- Chapter 4. One Size Does Not Fit All in Remote Anatomy Teaching -- Chapter 5. From Lecture Halls to Zoom Links: How Can Educational Theory Help Us to Deliver Effective and Engaging Teaching in an Online Environment? -- Chapter 6. Collaborative, Two-Directional Live Streaming to Deliver Hands-on Dissection Experience during the COVID-19 Lockdown -- Chapter 7. Livestreaming Can Augment the Observation of Veterinary Post-mortem Examinations -- Chapter 8. Virtual Reality for Anatomy and Surgical Teaching -- Chapter 9. Can Synchronous Online Near-Peer Teaching Offer the Same Benefits as the Face-to-Face Version When Used in Clinical Neuroanatomy Education? -- Chapter 10. COVID-19 Adaptations with Virtual Microscopy -- Chapter 11. The Challenges of Visualisation During Delivery and Assessment of Clinical Teaching Under COVID-19: A Reflective Account of Problem Solving -- Chapter 12. Not for Room 101.
    Abstract: This book focuses on the challenges to biomedical education posed by the lockdowns and restrictions to on campus teaching brought about by the COVID-19 pandemic and highlights the tools and digital visualization technologies that have been successfully developed and used for remote teaching. Biomedical education for science, medical, dental and allied health professionals relies on teaching visual and tactile knowledge using practice-based approaches. This has been delivered for decades via on-campus lectures, workshops and laboratories, teaching practical skills as well as fundamental knowledge and understanding. However, the arrival of the COVID-19 pandemic meant that education across the globe had to pivot very quickly to be able to deliver these skills and knowledge in a predominantly online environment. This brought with it many challenges, as Higher Education staff, had to adapt to deliver these visual subjects remotely. This book addresses the challenges and solutions faced by Higher Education staff in teaching visual content in distance education. Chapters include literature reviews, original research, and pedagogical reflections for a wide range of biomedical subjects, degrees such as medicine, dentistry and veterinary sciences with examples from undergraduate and postgraduate settings. The goal of the book is to provide a compendium of expertise based on evidence gathered during the COVID-19 pandemic, as well as reflections on the challenges and lessons learned from this dramatic shift in teaching. It also presents new examples of best practices that have emerged from this experience to ensure that they are not lost as we return to on-campus learning in a new era of biomedical teaching. This book will be of interest to anyone looking for a helpful reference point when designing online or blended teaching for visual practice-based subjects.
    Type of Medium: Online Resource
    Pages: X, 228 p. 56 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031171352
    Series Statement: Advances in Experimental Medicine and Biology, 1397
    URL: https://doi.org/10.1007/978-3-031-17135-2
    DOI: 10.1007/978-3-031-17135-2
    DDC: 610.72
    Language: English
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  • 30
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    Online Resource
    Biological Effects of Static Magnetic Fields (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biomedical Research. ; Cell Biology.
    Description / Table of Contents: Chapter 1. Magnetic Field Parameters and Biological Sample Differences that Lead to Differential Bioeffects -- Chapter 2. Static Magnetic Field Direction-induced Differential Biological Effects -- Chapter 3. Magnetic Properties of Biological Samples -- Chapter 4. Molecular Mechanisms for Electromagnetic Field Biosensing -- Chapter 5. Controlling Cell Membrane Potential with Static Non-uniform Magnetic Fields -- Chapter 6. Impact of Static Magnetic Fields on Cells -- Chapter 7. Impact of Static Magnetic Fields on Microorganisms, Plants and Animals -- Chapter 8. Static Magnetic Fields on Human Bodies -- Chapter 9. Potential Applications of Static Magnetic Fields in Cancer Treatment -- Chapter 10. Effects of Static Magnetic Fields on Diabetes and Its Complications -- Chapter 11. Impacts of Static Magnetic Field on Bone Health -- Chapter 12. Effects of Static Magnetic Fields on the Immune System -- Chapter 13. Biological Effects of Static Magnetic Fields on the Nervous System -- Chapter 14. The Biological Effects of Long-term Static Magnetic Field Exposure -- Chapter 15. Prospects, Pitfalls, and Opportunities for Human Static Magnetic Field Therapy.
    Abstract: The book summarizes the emerging topic about the effects of SMF on biological samples ranging from single molecules, subcellular compartments, and cells to whole organisms. It also discusses the potential application of SMF in clinical treatment of cancer, pain, diabetes and other diseases. With the development and growing popularity of modern appliances like MRI in hospitals, the potential impact of magnetic fields on human health is invoking increasing concerns. At the same time, SMF has been explored in the treatment of tumor and other diseases for decades. Nevertheless, there are still some reservations and uncertainties about these treatments, which are largely due to the differential biological effects reported in the literature. These experimental inconsistencies are mainly caused by variations such as different magnetic field types, intensities, treatment time, as well as biological samples examined. The second edition added eight new chapters about new progress in this field including impacts of SMFs, magnetism of biomolecules, and potential of SMFs in the management of bone, pain, diabetes, and immune systems. This volume will help clarify some dilemmas in this field and encourage further investigations in order to achieve a better understanding of the biological effects of SMF, aiming for a rational application of SMF in clinical therapy in the near future. The book is useful for scientists, doctors, and students who are interested in magnetic fields and life sciences.
    Type of Medium: Online Resource
    Pages: XV, 420 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811988691
    URL: https://doi.org/10.1007/978-981-19-8869-1
    DOI: 10.1007/978-981-19-8869-1
    DDC: 610.72
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    Myosins : A Superfamily of Molecular Motors (2020)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Proteins . ; Cytology. ; Proteins. ; Biomedical Research. ; Protein Biochemistry. ; Cell Biology. ; Proteins.
    Description / Table of Contents: Introduction -- Myosin Structure -- Cargo Binding by Unconventional Myosins -- Cryo-EM of Actin-Myosin Structures -- Small Molecule Effectors of Myosin Function -- Single-Molecule Biophysical Techniques to Study Actomyosin Force Transduction -- High-Speed Atomic Force Microscopy to Study Myosin Motility -- How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches -- How Actin Tracks Affect Myosin Motors -- Myosins in the Nucleus -- Myosins in Cytokinesis -- Myosins and Disease -- Myosins and Hearing -- The Actomyosin Systems in Apicomplexa -- Approaches to Identify and Characterise MYO6-Cargo Interactions -- Class IX Myosins: Motorized RhoGAP Signaling Molecules -- Myosin X -- Myosin XVI -- Myosin XVIII -- Myosin XIX.
    Abstract: Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular activities including cell structure, cell migration, intracellular trafficking, and cell-cell contact. Importantly, loss of function and mutation are associated with diseases including myopathies, hearing impairment, glomerulosclerosis, and cancer. Written by international experts in myosin motors and the approaches used to study them, this book is expected to provide a comprehensive assessment of the current status of our understanding of the structure and molecular mechanism of myosins and their cellular roles.
    Type of Medium: Online Resource
    Pages: XI, 455 p. 116 illus., 97 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030380625
    Series Statement: Advances in Experimental Medicine and Biology, 1239
    URL: https://doi.org/10.1007/978-3-030-38062-5
    DOI: 10.1007/978-3-030-38062-5
    DDC: 610.72
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    Online Resource
    Single-cell Sequencing and Methylation : Methods and Clinical Applications (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Cancer. ; Biomedical Research. ; Bioinformatics. ; Cancer Biology.
    Description / Table of Contents: Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.
    Abstract: With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.
    Type of Medium: Online Resource
    Pages: VIII, 247 p. 117 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811544941
    Series Statement: Advances in Experimental Medicine and Biology, 1255
    URL: https://doi.org/10.1007/978-981-15-4494-1
    DOI: 10.1007/978-981-15-4494-1
    DDC: 610.72
    Language: English
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    Beyond IPM: Introduction to the Theory of Holistic Pest Management (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Agriculture. ; Microbiology. ; Zoology. ; Plant Science. ; Agriculture. ; Microbiology. ; Zoology.
    Description / Table of Contents: 1. Introduction: Beyond IPM -- 2. The Nature of Integrated Pest Management -- 3. The Need for a Holistic Approach to Pest Management -- 4. Theoretical Support of Holistic Pest Management -- 5. Methods for analysis of Holistic Pest Management -- 6. Implementing Holistic Pest Management -- 7. Holistic Science in Pest Management: Winds of Change.
    Abstract: About 15 years ago, we asked ourselves why the methods developed by the research institutions for the management of pests were almost not used by small landholder farmers. It seemed obvious to us that conventional pest control –called “Integrated Pest Management”– was based on a reductionist approach. In reviewing the literature on the subject, we found that our concern was not new or unique. The agreement of some authors with our ideas reinforced our efforts to find a holistic approach to pest management. We took two central ideas to develop the holistic approach: First, pest management actions must put the farmer at the center of the system. Second, pest management must consider not only both pests but the other important components of the system in question. This approach based on the farmers and the systems in which they are immersed, is called “Holistic Pest Management” or HPM. In this book, I present the philosophy and practice of HPM, a new paradigm of pest management.
    Type of Medium: Online Resource
    Pages: XXX, 154 p. 34 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030433703
    Series Statement: Sustainability in Plant and Crop Protection, 15
    URL: https://doi.org/10.1007/978-3-030-43370-3
    DOI: 10.1007/978-3-030-43370-3
    DDC: 580
    Language: English
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    Online Resource
    Problem Solving Questions in Toxicology : A Study Guide for the Board and other Examinations (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Biomedical Research. ; Pharmacology.
    Description / Table of Contents: Part 1 General and Principles of Toxicology -- A Historical Glimpse and Stalwarts -- General Toxicology -- Principles of Toxicology -- Mechanism of Toxicity -- Part 2 Disposition and Kinetics -- Disposition of Toxicants -- Toxicokinetic of Xenobiotics -- Part3 Organ Toxicity -- Target Organ Toxicity -- Part4 Non-Organ-Directed Toxicity -- chemical carcinogenesis -- Genetic Toxicology -- Developmental Toxicology -- Part5 Toxic Agents -- Pesticides -- Metals and Micronutrients -- Solvents. Gasses and Vapors -- Toxicology of Nanomaterial Particles -- Toxic Effects of Calories -- Part6 Plants, Biotoxins and Food Poisonings -- Plant Toxicity -- Biotoxins and Venomous Organisms -- Poisonous Foods and Food Poisonings -- Part7 Radioactive Materials -- Radiation and Radioactive Materials -- Part8 Applications of Toxicology -- Food Toxicology -- Ecotoxicology -- Environmental Toxicology -- Analytical and Clinical Toxicology -- Occupational Toxicology. .
    Abstract: The book provides easy-to-understand diverse specialized topics in toxicology using self- study questions and answers. The answers are in the form of text along with custom made diagrams and explanations that help the student audience to understand and grasp the matter easily. Problem Solving Questions in Toxicology is written specifically as a study guide for the toxicology board and other examinations. .
    Type of Medium: Online Resource
    Pages: XV, 346 p. 46 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504090
    URL: https://doi.org/10.1007/978-3-030-50409-0
    DOI: 10.1007/978-3-030-50409-0
    DDC: 610.72
    Language: English
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    Online Resource
    The Flax Genome (2023)
    Cham :Springer International Publishing :
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    Keywords: Botany. ; Genetics. ; Biotechnology. ; Plant Science. ; Genetics and Genomics. ; Biotechnology.
    Description / Table of Contents: Reference genome sequence of flax -- Repeat DNA sequences in flax genomes -- Pale flax (Linum bienne): an underexplored flax wild relative -- Flax breeding -- QTL mapping: strategy, progress and prospects in flax -- Genetics of abiotic stress in flax. QTL and candidate genes for flax disease resistance -- Key stages of flax bast fiber development through the prism of transcriptomics -- Metabolomics and transcriptomics-based tools for linseed improvement.
    Abstract: The Flax Genome is a comprehensive compilation of most recent studies focused on reference genome, genetic resources and molecular diversity, breeding, QTL mapping, gene editing tools, functional genomics and metabolomics, molecular breeding via genomic selection, and genomic resources. The flax genome reference sequences and the new genome assemblies are presented. A list of flax QTL and candidate genes associated with more than 35 traits, including yield and agronomic, seed quality and fatty acid composition, fibre quality and yield, abiotic stress, and disease resistance traits, are summarized. A QTL- based genomic selection strategy and genome–editing tools are systematically introduced. In addition, huge amounts of flax genomic resources generated in the last decade are summarized. The book contains 13 chapters with about 390 pages authored by globally reputed researchers in the relevant fields to this crop The book is intended to be useful to students, teachers, and researchers interested in traditional and molecular breeding, pathology, molecular genetics and breeding, bioinformatics and computational biology, and functional genomics.
    Type of Medium: Online Resource
    Pages: XII, 294 p. 74 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031160615
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-031-16061-5
    DOI: 10.1007/978-3-031-16061-5
    DDC: 580
    Language: English
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    Online Resource
    Progress in Botany Vol. 82 (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Forestry. ; Botanical chemistry. ; Biotic communities. ; Plant genetics. ; Plant physiology. ; Plant Science. ; Forestry. ; Plant Biochemistry. ; Ecosystems. ; Plant Genetics. ; Plant Physiology.
    Description / Table of Contents: 1.Tools Shape Paradigms of Plant-Environment Interactions -- 2.Gene Expression in Coffee -- 3. Cross-Talk Between Sporophyte and Gametophyte During Anther and Ovule Development In Angiosperms -- 4. The Photosynthetic System in Tropical Plants Under High Irradiance and Temperature Stress -- 5. Plant Peroxisomes and Their Metabolism of ROS, RNS, and RSS -- 6. Ammonium Assimilation and Metabolism in Rice -- 7. How can we Interpret the Large Number and Diversity of Abscisic Acid Transporters? -- 8. Orient in the World with a Single Eye: The Green Algal Eyespot and Phototaxis -- 9. Bidirectional Lateral Transport Barriers in Serving Plant Organs and Integral Plant Functioning: Localized Lignification, Suberinization, and Cutinization -- 10. The Haustorium of Phytopathogenic Fungi: A Short Overview of a Specialized Cell of Obligate Biotrophic Plant Parasites -- 11. Transmission of Phloem-Limited Viruses in the Host Plants by Their Aphid Vectors -- 12. Biotechnology for Biofuel Production -- 13. Modelling Urban Tree Growth and Ecosystem Services: Review and Perspectives.
    Abstract: With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. This latest volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.
    Type of Medium: Online Resource
    Pages: XII, 464 p. 76 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030686208
    Series Statement: Progress in Botany, 82
    URL: https://doi.org/10.1007/978-3-030-68620-8
    DOI: 10.1007/978-3-030-68620-8
    DDC: 580
    Language: English
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    RNA-Based Technologies for Functional Genomics in Plants (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Plant genetics. ; Physiology. ; Plant Science. ; Plant Genetics. ; Physiology.
    Description / Table of Contents: Artificial Small RNAs for Functional Genomics in Plants -- Use of mRNA-interactome capture for generating novel insights into plant RNA biology -- Improving nutrient value of crops: Applications of RNAi in targeting plant metabolic pathways -- Utilizing RNA-based approaches to understand plant-insect interactions.
    Abstract: This book offers a unique and comprehensive overview of key RNA-based technologies, as well as their development and applications for the functional genomics of plant coding and non-coding genes. It focuses on the latest as well as classical RNA-based techniques used for studies on small RNAs, long non-coding RNAs and protein-coding genes. These techniques chiefly focus on target mimics (TMs) and short tandem target mimics (STTMs) for small RNAs, and artificial microRNAs (amiRNAs), RNA interference (RNAi) and CRISPR/Cas for genes. Furthermore, the book discusses the latest trends in the field and various modifications of the above-mentioned approaches, and explores how these RNA-based technologies have been developed, applied and validated as essential technologies in plant functional genomics. RNA-based technologies, their mechanisms of action, their advantages and disadvantages, and insights into the further development and applications of these technologies in plants are discussed. These techniques will enable the users to functionally characterize genes and small RNAs through silencing, overexpression and editing. Gathering contributions by globally respected experts, the book will appeal to students, teachers and scientists in academia and industry who are interested in horticulture, genetics, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture & genetic engineering, and functional genomics. .
    Type of Medium: Online Resource
    Pages: XIII, 428 p. 48 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030649944
    Series Statement: Concepts and Strategies in Plant Sciences,
    URL: https://doi.org/10.1007/978-3-030-64994-4
    DOI: 10.1007/978-3-030-64994-4
    DDC: 580
    Language: English
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    Agrochemicals in Soil and Environment : Impacts and Remediation (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Agriculture. ; Agronomy. ; Biotechnology. ; Nanotechnology. ; Plant Science. ; Agriculture. ; Agronomy. ; Biotechnology. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Agrochemicals in Soil and Environment: An Overview -- Chapter 2. Agrochemicals- Provenance, Environmental Fate and Remediation Measures -- Chapter 3. Impact of Agrochemicals on Soil Microbiota -- Chapter 4. Agriculture Pollution in Kerala, India with Special Reference to Endosulphan -- Chapter 5. An Intergenerational Community-Based Approach to Safe Farming and Environmental Health -- Chapter 6. Guidance on Pesticides Handling in Farming -- Chapter 7. Impact of Pesticides, Herbicides and Insecticides on the Ecosystem -- Chapter 8. Pesticides and its Effects on Plants: A Case Study of Deltamethrin -- Chapter 9. The Use of Glyphosate in Regions of Argentina and Colombia and its Socio-environmental Impacts -- Chapter 10. Impact of Insecticides on Soil and Environment and their Management Strategies -- Chapter 11. Role of Insect Pest Management in Agriculture Conservation -- Chapter 12. Mobility of Trace Elements in Agricultural Soils- Chapter 13. The effects of nutrient enrichment on nutrient-poor ecosystems: Insights from the study of serpentine soil plant relations -- Chapter 14. Soil Erosion and Sedimentation - A Source of Contamination and Impact on Agriculture Productivity -- Chapter 15. Plastics in the Soil Environment: An Overview -- Chapter 16. Lead and cadmium contamination in the soil environment: Impacts on plant growth and human health -- Chapter 17. Heavy metals contamination on farmlands in the crude oil exploration area -- Chapter 18. Effect of Trace Elements in Soils and Its Management -- Chapter 19. Remediation of Agrochemicals in Soil and Environment -- Chapter 20. Alleviation in the Toxicity of Heavy Metals on Agricultural Crops by Metal Resistant Bacteria -- Chapter 21. Bioremediation Strategies to Mitigate the Impact of Atrazine in the Environment: Recent Advances and Prospects. Chapter 22. Aspergillus Mediated Bioremediation of Agrochemicals- Current Progress and Future Perspectives -- Chapter 23. Implications of Phytohormones as Agro-chemicals under Dynamic Environmental Conditions -- Chapter 24. Role of Genetically Modified Bacteria for Alleviating of Agrochemical Impact on the Environment -- Chapter 25. ‘Omics Perspective’ - Molecular Blue-print for Agrochemical Remediation -- Chapter 26. Impact and Remediation of Agrochemicals in Soil and Environment: Conclusions and Future Perspectives.
    Abstract: This volume ‘Agrochemicals in Soil and Environment: Impacts and Remediation’ is a comprehensive collection of important literature on agrochemical contamination. The main focus of this book is to point out undesirable changes in biological, physical and chemical characteristics of agricultural soils and its impacts on global agricultural crop productivity. Soil is one of the important resources of basic needs for our sustenance but due to various anthropogenic activities like urbanization and industrialization, the soil is losing its basic quality characteristics. Soil microorganisms, water holding capacity, minerals, salts and nutrients are under the direct threat due to agrochemicals therefore, agricultural sector is facing a serious challenge. Lack of proper knowledge and luxurious applications of agrochemicals resulting into degradation and deterioration of soil quality, loss of soil and crop productivity and threatening the food security. Therefore, it is imperative to develop indices, indicators and soil parameters for the monitoring and impact assessment of agricultural contaminants. Further, biotic and abiotic stresses and their tolerance mechanisms in plants in relation to the soil contaminants such as toxic pollutants, heavy metals, inorganic and organic matters, variety of pesticides, insecticides, herbicides, agricultural runoffs and solid wastes, and chemical fertilizers are also highlighted in this volume. This book also discusses causes of reduced agriculture productivity and suggests sustainable measures such as plant-based technologies, bioremediation and nanotechnology, that can be used to overcome the crop losses. The book is interest to research students, teachers, agricultural scientists, agronomists, environmentalists as well as policy makers.
    Type of Medium: Online Resource
    Pages: XXVI, 612 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811693106
    URL: https://doi.org/10.1007/978-981-16-9310-6
    DOI: 10.1007/978-981-16-9310-6
    DDC: 580
    Language: English
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    Freshwater Red Algae : Phylogeny, Taxonomy and Biogeography (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Ecology . ; Water. ; Hydrology. ; Plant Science. ; Ecology. ; Water. ; Water. ; Water.
    Description / Table of Contents: History of freshwater red algae; taxonomic diversity and phylogeny; biogeographic trends; how to collect freshwater red algae; scope and organization of this book -- Subphylum Cyanidiophytina: Class Cyanidiophyceae; Subphylum Proteorhodophytina: Classes Compsopogonophyceae, Porphyridiophyceae, Rhodellophyceae and Stylonematophyceae -- Subphylum Eurhodophytina: Classes Bangiophyceae and Florideophyceae (Subclasses Corallinophycidae, Hildenbrandiophycidae and Rhodymeniophycidae) -- Subphylum Eurhodophytina: Class Florideophyceae, Subclass Nemaliophycidae, Orders Acrochaetiales, Balbianiales and Thoreales -- Subphylum Eurhodophytina: Class Florideophyceae, Subclass Nemaliophycidae, Order Batrachospermales.
    Abstract: This book presents the phylogeny, taxonomy and biogeography of freshwater red algae. Its content is divided into five chapters. The first chapter provides a brief history of freshwater red algal research, habits and collecting methods, general biogeographic trends and an overview of the taxonomic/phylogenetic placement of freshwater taxa. The other four chapters are taxonomic treatments of non-marine red algae based on taxonomic levels, i.e. classes within the phylum Rhodophyta, orders within each class, families within each order, and genera within each family. Descriptions, phylogenetic data (including numerous trees), geographic range (maps for most species) and dichotomous keys for identification are presented. Comprehensive data are provided for more than 220 species.
    Type of Medium: Online Resource
    Pages: XII, 338 p. 113 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030839703
    URL: https://doi.org/10.1007/978-3-030-83970-3
    DOI: 10.1007/978-3-030-83970-3
    DDC: 580
    Language: English
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  • 40
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    Online Resource
    Deciphering Drug Targets for Alzheimer’s Disease (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biology. ; Neurosciences. ; Biotechnology. ; Drug delivery systems. ; Biomedical Research. ; Biological Sciences. ; Neuroscience. ; Biotechnology. ; Drug Delivery.
    Description / Table of Contents: Chapter 1.Deciphering New Drug Targets in Alzheimer’s Disease -- Chapter 2. Novel Therapeutic Targets for Treating Alzheimer’s Disease -- Chapter 3. Modified Investigation Tools and Techniques Useful in Alzheimer’s Disease Research -- Chapter 4. Dual Specificity Tyrosine Phosphorylation Regulated Kinase1A (DYRK1A) Inhibitors: The Quest for a Disease-Modifying Treatment for Alzheimer’s Disease -- Chapter 5. β-secretase as a primary drug target of Alzheimer disease: Function, Structure, and Inhibition -- Chapter 6. Endocrine Receptors: The Potential Therapeutic Targets for Alzheimer’s -- Chapter 7. Calcium Channels as a Potential Therapeutic Target for Alzheimer’s Disease -- Chapter 8. Traversing Through the Trajectory of Pathogenic Astrocytes in Alzheimer’s Disease -- Chapter 9. Targeting Mitochondrial Dynamics as a Restorative Approach in the Treatment of Alzheimer’s Disease -- Chapter 10. Epigenetic Therapy for Alzheimer’s Disease -- Chapter 11. Exploring the Diverse Roles of GSK-3ß Kinase in Alzheimer’s Disease -- Chapter 12. Role of Target Fishing in Discovery of Novel Anti-Alzheimer’s Agents: In Silico Applications -- Chapter 13. Multi-Target Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery -- Chapter 14. Investigating the Role of Tau Proteins in Alzheimer’s Disease-From Typical Functioning MAPs to Aberrant Fibrillary Deposits in the Brain -- Chapter 15. The Overview of Drugs Used in Alzheimer’s Disease and Their Molecular Targets.
    Abstract: This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.
    Type of Medium: Online Resource
    Pages: XV, 381 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819926572
    URL: https://doi.org/10.1007/978-981-99-2657-2
    DOI: 10.1007/978-981-99-2657-2
    DDC: 610.72
    Language: English
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    Nutraceuticals and Cancer Signaling : Clinical Aspects and Mode of Action (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Nutrition   . ; Food science. ; Chemistry, Organic. ; Biomedical Research. ; Nutrition. ; Food Science. ; Organic Chemistry.
    Description / Table of Contents: Part I: An overview of cancer and its mechanisms -- 1-A brief overview of cancer, its mechanisms, and prevention methods -- 2-MECHANISMS INVOLVED IN CARCINOGENESIS -- Part II: Functional foods/nutraceuticals as chemo preventive agents -- 3-Tomato (lycopene and β-carotene) and cancer -- 4-Essential Oils from Aromatic Plants in cancer prevention and treatment -- 5-Bee propolis (caffeic acid phenethyl ester) against cancer -- 6-Brown Algae (Fucoxanthin) Against Cancer -- 7-Cruciferous vegetables (indole-3-carbinol, isothiocyanates) against cancer -- 8-Crustacea (carotenoids namely astaxanthins) against cancer -- 9-Curcuma and breast cancer: a focus on cell signaling pathways -- 10-FRUITS AND VEGETABLES IN CANCER -- 11-Garlic: Allyl Sulfur Compounds and Cancer Prevention -- 12-Ginger (gingerols and 6-shogaol) against cancer -- 13-Saffron (crocins) against cancer -- 14-OLIVE LEAF (OLEUROPEIN) AND ITS ROLE IN CANCER: THERAPEUTIC UPDATES -- 15-Honey against cancer -- 16-Soybeans and phytoestrogen rich foods (genistein, daidzein) against cancer -- 17-Tea (catechins including (-)-epigallocatechin-3-gallate) and cancer -- 18-Probiotics and Cancer -- Part III: The role of nutrients in the prevention of cancer -- 19-Vitamins (C, D and E) against cancer -- 20-Minerals (namely selenium) and cancer -- 21-Dietary fibers/beta-glucan and cancer -- 22-Omega-3 Polyunsaturated Fatty Acids and Cancer.
    Abstract: Today's consumers are looking for food products with health-promoting roles in addition to nutritional benefits. With current research showing that nutraceuticals and functional foods rich in specific bioactives may have chemopreventative effects, these products are increasingly popular. However, while much in the literature supports the health-promoting features of these foods, few texts focus on their bioactive agents and their mode of action in cancer signaling. Nutraceuticals and Cancer Signalling: Clinical Aspects and Mode of Action explains the link between nutraceuticals and cancer in terms of clinical trials and modes of action. This book gives an overview of common cancers and their mechanisms, and the most common functional foods and their bioactive components. Individual chapters focus on specific functional foods--including tomatoes, garlic, honey, tea, yoghurt, and many more--their prominent bioactive compounds, and their mode of action in cancer signaling and chemoprevention. Recent findings on cancer-prevention roles of different vitamins and minerals are also discussed. For food scientists, nutritionists, and pharmaceutical experts looking to understand how functional foods can play a role in fighting cancer, this text serves as a one-stop reference.
    Type of Medium: Online Resource
    Pages: IX, 652 p. 52 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030740351
    Series Statement: Food Bioactive Ingredients,
    URL: https://doi.org/10.1007/978-3-030-74035-1
    DOI: 10.1007/978-3-030-74035-1
    DDC: 610.72
    Language: English
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    Opuntia spp.: Chemistry, Bioactivity and Industrial Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Food science. ; Plant Science. ; Food Science.
    Description / Table of Contents: 1-Introduction to Opuntia spp.: Chemistry, bioactivity and Industrial Applications -- 2-South African perspective on Opuntia spp.: cultivation, human and livestock food and industrial applications -- 3-Ethnobotany, medicinal utilization and Systematics of Opuntia species from Deserts of Pakistan -- 4-Cactus Pear (Opuntia spp.) Species and Cultivars -- 5-Classification, Distribution and Morphological Characterization of Opuntia species -- 6-Cultivation and Cultural Practices of Opuntia spp -- 7-Molecular characterization of Opuntia spp -- 8-Genetic diversity and ecotypes of Opuntia spp -- 9-Potential attribute of crassulacean acid metabolism of Opuntia spp. production in water-limited conditions -- 10-Harvest and Postharvest Technology of Opuntia spp -- 11-Chemistry and functionality of Opuntia spp. nopal cladodes -- 12-Opuntia ficus-indica (L.) Mill. Bioactive Ingredients and Phyto-constituents -- 13-Opuntia Fiber and its Health-Related Beneficial Properties -- 14-Opuntia spp. chemical constituents and bioactive compounds, with particular regards to polyphenols -- 15-Profile and Biological Properties of the main Phenolic compounds in cactus pear (Opuntia spp.) -- 16-Opuntia spp. essential oils -- 17-Antioxidant activity of Opuntia spp.: A review -- 18-Natural antimicrobial molecules from Opuntia spp. and their role in poultry nutrition -- 19-Genus Opuntia: A golden source of compounds with anti-inflammatory potential -- 20-Opuntia spp. benefits in chronic diseases -- 21-Traceability of Opuntia spp -- 22-Antidiabetic Activity of Opuntia spp -- 23-Anticancer Activity of Opuntia spp -- 24-Innovative technologies for the identification of chemical and bioactive compounds in Opuntia spp. plant, food and waste -- 25-Innovation technologies for extracting Opuntia spp. seed oil -- 26-Novel pectins from prickly pear (Opuntia albicarpa) fruits: structural features and rheological properties -- 27-Modern Technologies in Opuntia spp. Juice Processing -- 28-Novel Technologies in Juice Processing from Opuntia spp. Fruits -- 29-Potential use of prickly pear juice prepared from shelf-grown cultivars as an authentic and nutritional fruit supplement -- 30-Fermented Beverages from Opuntia species: Composition, Commercialization and Future Outlook -- 31-Opuntia spp. Marmalade -- 32-Opuntia pear peel as a source of functional ingredients and their utilization in meat products -- 33-Opuntia spp. Seed Oil -- 34-Prickly pear (Opuntia ficus indica) processing by extrusion-cooking -- 35-Opuntia spp. and Extruded Food Products -- 36-Opuntia spp. Extruded Food Products -- 37-Industrial uses of Opuntia spp. by-products -- 38-Bread Enrichment with Opuntia spp. Derivatives -- 39-Opuntia spp. products and by-products as a potential source of edible films and coatings -- 40-Microencapsulation technology: an alternative preservation method for Opuntia spp. derived products and their bioactive compounds -- 41-Prickly pear (Opuntia spp.) in animal and poultry feed -- 42-Industrial applications of Opuntia spp. (nopal, fruit and peel) -- 43-Opuntia spp. as a source of sugars for the ethanol production -- 44-Opuntia spp. in biogas production -- 45-Opuntia spp. in dye-sensitized solar cells -- 46-Incorporation of Opuntia spp. into Food Systems -- 47-Opuntia spp. in cosmetics and pharmaceuticals -- 48-Food and non-food applications of Opuntia spp. seed oil -- 49-Opuntia spp. in the textile industry -- 50-Cactus pear as colorants and coloring foods: application in different food matrices.
    Abstract: The Opuntia fruits, commonly known as cactus pears or prickly pears, have been suggested by the Food and Agriculture Organization to be a promising and strategic crop in regions suffering from lack of water. In Mexico, India, South Africa, and the Mediterranean, the Opuntia fruits have become popular due to their nutritive value and health-promoting benefits, including antioxidant, antiulcerogenic and antiatherogenic traits and protective effects against LDL oxidation. Additionally, readily absorbable sugars, high vitamin C and mineral content, and a pleasant flavour make Opuntia tailor-made for novel food. Due to their ecological advantages, high functional value, and health-related traits, Opuntia fruits can be highly exploited in different food processing applications. For instance, Opuntia cactus fruits are used for the preparation of juices and marmalades; Opuntia cactus plants are used to feed animals in African and Latin American countries; Peruvian farmers cultivate Opuntia cactus for growing the cochineal (Dactylopius coccus) insect and producing the natural dye carmine; and the commercial production of food and non-food products from Opuntia has been established in Mexico, USA and several Mediterranean countries. Opuntia spp.: Chemistry, Bioactivity and Industrial Applications creates a multidisciplinary forum of discussion on Opuntia cactus with special emphasis on its horticulture, post-harvest, marketability, chemistry, functionality, health-promoting properties, technology and processing. The text includes detailed discussion of the impact of traditional and innovative processing on the recovery of high-added value compounds from Opuntia spp. by-products. Later chapters explore the potential applications of Opuntia spp. in food, cosmetics and pharmaceutical products.
    Type of Medium: Online Resource
    Pages: XIX, 1059 p. 98 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030784447
    URL: https://doi.org/10.1007/978-3-030-78444-7
    DOI: 10.1007/978-3-030-78444-7
    DDC: 580
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    Fruits of the Brazilian Cerrado : Composition and Functional Benefits (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Botanical chemistry. ; Food science. ; Medicine, Preventive. ; Health promotion. ; Agriculture. ; Plant Science. ; Plant Biochemistry. ; Food Science. ; Health Promotion and Disease Prevention. ; Agriculture.
    Description / Table of Contents: 1. Acrocomia aculeata -- 2. Attalea dubia & Attalea phalerata -- 3. Campomanesia genus -- 4. Caryocar spp -- 5. Mauritia flexuosa -- 6. Dipteryx alata -- 7. Solanum lycocarpum -- 8. Attalea speciosa -- 9. Syagrus romanzoffiana -- 10. Hancornia speciosa.
    Abstract: Fruits of the Brazilian Cerrado: Composition and Functional Benefits describes the nutritional, chemical and physical characteristics of the fruits of the Cerrado, as well as their pharmacological effects and use in phytotherapics. Chapters are dedicated to the morphological characteristics, macronutrients, micronutrients and active compounds of various fruits, with separate sections covering their peels, leaves, nuts, pulps, and other components. The text also includes detailed studies on the treatment of diseases with these natural products, as well as their applications in popular use by local communities. Authors explain the importance of bioactive compounds found in the fruits and their possible mechanisms of action in the organism. This text thus provides a valuable reference to researchers studying a range of topics, including functional foods, phytotherapy, and plant science.
    Type of Medium: Online Resource
    Pages: XIII, 186 p. 31 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030629496
    URL: https://doi.org/10.1007/978-3-030-62949-6
    DOI: 10.1007/978-3-030-62949-6
    DDC: 580
    Language: English
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  • 44
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    Online Resource
    Regionalized Management of Medicine (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Medicine Research. ; Biology Research. ; Therapeutics. ; Medical informatics. ; Translational Research. ; Therapeutics. ; Health Informatics.
    Description / Table of Contents: Introduction: The importance of regionalized management of medicine -- Alcohol use disorders -- Public-private partnerships management in health care: The Portuguese experience -- Management of Clinical Precision Medicine -- Artificial Intelligence in medical management -- Advanced Demand Forecasting and Inventory Management Methods in Hospital Pharmacy -- Clinical Application of Cell-Based Therapies Opportunities and Challenges -- Management of Next-Generation Sequencing (NGS) in Precision Medicine -- Exploration on the Reform of County Medical Integration -- The Regionalization of Medical Management: The Practice and Exploration of Established Fudan-Minhang Medical Alliance -- Bed-occupancy management and hospital planning: a handbook -- Management of severe childhood pneumonia in low resource setting -- The role of mitochondrial-targeted antioxidant, MitoQ, in neurodegenerative disease -- Progression of mitochondria research for clinical potentials -- DNA methylation in pulmonary inflammatory diseases -- Synthetic lethality and lung cancer.
    Abstract: The Book mainly focuses on various aspects of regionalized management of medicine, related with updates of new biotechnology, application of therapeutic strategy, and understanding of disease-associated molecular mechanisms. The book also discusses how medical informatics, systems analysis, database sharing, and artificial intelligent can be applied for improving the quality of hospital managements, disease therapies, regional collaborations, and medical services. This book serves as a professional reference book to clinicians and experts who are interested in medical informatics and artificial intelligence for diseases therapies and therapeutic strategy, better systems analysis and database sharing, and more efficient regional collaborations and medical services.
    Type of Medium: Online Resource
    Pages: X, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811678936
    Series Statement: Translational Bioinformatics, 17
    URL: https://doi.org/10.1007/978-981-16-7893-6
    DOI: 10.1007/978-981-16-7893-6
    DDC: 610.72
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  • 45
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    Online Resource
    Medicinal and Aromatic Plants of India Vol. 1 (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Agronomy. ; Plant diseases. ; Plant Science. ; Agronomy. ; Plant Pathology.
    Description / Table of Contents: Chapter 1. History of medicinal plants research in India -- Chapter 2. Importance of medicinal and aromatic plants in our day-to-day life -- Chapter 3. Major diseases of important medicinal and aromatic plants An Indian subcontinent perspective -- Chapter 4. Introduction to MAPs in India : Distribution , diversity and conservation and uses -- Chapter 5. Diversity of MAPs in India and its potential -- Chapter 6. Ethnomedicinal , phytochemistry and pharmacological properties of Arnebia species -- Chapter 7. Diversity of medicinal and aromatic plants with special reference to endemic plants of India -- Chapter 8. Distribution, chemical composition and ethnomedicinal appraisal of endangered medicinal plants of Kashmir Himalaya , India -- Chapter 9. Chemical diversity and ethnobotanical survey of Indian MAP species -- Chapter 10. Traditional uses of medicinal and aromatic plants among Indian tribes -- Chapter 11. Opportunities and challenges in ethnobotanical survey of Indian medicinal and aromatic plants -- Chapter 12. Breeding of MAPs in India : Achievements and prospects -- Chapter 13. Conservation of wild MAPs : Constraints achievements and prospects -- Chapter 14. Quality assurance and quality control of MAPs in India -- Chapter 15. Chromatographic analysis of medicinal plants for quality control -- Chapter 16. Expanding horizones : Role of biotechnology in MAP research, production and utilization -- Chapter 17. Role of biotechnology in MAP research, production and utilization -- Chapter 18. Integrated transcriptomics and proteomics approaches to study secondary metabolic pathways in medicinal plants: Recend trends -- Chapter 19. Demand and use of medicinal plants of India -- Chapter 20. Major diseases of medicinal and aromatic plants : An overview of constraints in production and management strategies -- Chapter 21. Role of medicinal and aromatic plants in the cosmetic industry -- Chapter 22. Harbouring the potential of medicinal and aromatic plants of India: A biotechnological approach -- Chapter 23. Quality assurance of cultivated and aromatic plants : Good agricultural and collection practices (GAP and GCP) -- Chapter 24. Breeding and Germplasm preservation of medicinal and aromatic plants of India.
    Abstract: This book is the 8th volume of the popular series ‘Medicinal and Aromatic Plants of the World’. Like the previous volumes, this volume is being introduced in a monographic format containing an extremely rich and diverse medicinal flora of India. Both well-known and somewhat still ignored species have been described in view of their traditional, present day and prospective uses. The scientific and technological achievements are also included aptly in this volume, together with a careful and critical consideration to our contemporary knowledge of this vast interdisciplinary domain with an Indian focus. In the era of global climate change and pandemics, building on the huge Indian traditions, this volume will make an important contribution to the better knowledge and understanding of MAPs. The Indian flora has always been recognized for its medicinal and aromatic plant values and this volume is explicitly focusing in that direction. With the rapidly expanding scope of natural nutraceuticals and herbal formulations, this book will be a fruitful acquisition for the interested readers globally.
    Type of Medium: Online Resource
    Pages: XVIII, 430 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030987015
    Series Statement: Medicinal and Aromatic Plants of the World, 8
    URL: https://doi.org/10.1007/978-3-030-98701-5
    DOI: 10.1007/978-3-030-98701-5
    DDC: 580
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  • 46
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    Microfluidics and Multi Organs on Chip (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Toxicology. ; Cytology. ; Biomedical Research. ; Biomedical Devices and Instrumentation. ; Toxicology. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Historical and Technological Background to Organs-on-a-Chip -- Chapter 2. Applications of microfluidics -- Chapter 3. Microfluidics based Organ-on-a-chip for cell biology studies -- Chapter 4. Microfluidics in Chemical biology -- Chapter 5. Role of microfluidics in drug delivery -- Chapter 6. Microfluidics in drug discovery -- Chapter 7. Microfludic based sensors -- Chapter 8. Background and Organs-on-a-Chip -- Chapter 9. Culture and co-culture of cells for multi organ on chip -- Chapter 10.Cells and organs on a chip in biomedical sciences -- Chapter 11. Futuristic aspects of organ on a chip -- Chapter 12. Development of Human on a chip -- Chapter 13. Multi-organ on a chip for personalized medicine -- Chapter 14. Development and application of Microfluids in organoid formation -- Chapter 15. Liver on a chip -- Chapter 16. Placenta on Chip: A Modern approach to probe feto-maternal interface -- Chapter 17. Microfluidic retina-on-chip -- Chapter 18. Heart on a chip -- Chapter 19. Kidney on a chip -- Chapter 20. Lungs on a chip -- Chapter 21. Brain on a chip -- Chapter 22. Skin on a chip -- Chapter 23. Organs-on-a-chip in preclinical studies -- Chapter 24. Application of organ on chip in blood brain barrier model -- Chapter 25. Multi organs on a chip in disease modeling -- Chapter 26. Prospects of Medical device on a chip -- Chapter 27. Lab on a chip for precision Medicine -- Chapter 28. Tumour-on-a-chip : Perfusion systems to model the extracellular breast tumour microenvironment:from tumour progression to metastasis formation -- Chapter 29. Building Human In Vitro 3D Models to Replace Animal Studies: During Drug Discovery Reearch: Scientific, Ethical and Regulatory Considerations.
    Abstract: This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
    Type of Medium: Online Resource
    Pages: IX, 717 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913792
    URL: https://doi.org/10.1007/978-981-19-1379-2
    DOI: 10.1007/978-981-19-1379-2
    DDC: 610.72
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  • 47
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    Application and Integration of Omics-powered Diagnostics in Clinical and Public Health Microbiology (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Diseases. ; Genetics. ; Immunology. ; Biomedical Research. ; Diseases. ; Genetics and Genomics. ; Immunology.
    Description / Table of Contents: Ch 1: Overview of Microbial NGS -- Ch 2: WGS for Bacterial Identification and Susceptibility Testing -- Ch 3: WGS for Bacterial Virulence Assessment -- Ch 4: Epidemiological Typing by WGS -- Ch 5: Bioinformatics Approaches for WGS Analysis -- Ch 6: WGS for Clinical Virology -- Ch 7: WGS for Clinical Mycology -- Ch 8: WGS for Clinical Parasitology -- Ch 9: Long Read Sequencing -- Ch 10: Aspects of WGS Integration -- Ch 11: Microbiome Analysis -- Ch 12: Metagenomics of Environmental Samples -- Ch 13: Clinical Metagenomics -- Ch 14: Metagenomics for Pathogen Discovery -- Ch 15: Advanced Applications for MALDI-TOF: Typing -- Ch 16: Advanced Applications for MALDI-TOF: Infectious Diseases and Antibiotic Susceptibility Testing (AST) -- Ch 17: Omics for Food and Water Microbiology -- Ch 18: Omics for Forensic and Post-Mortem Microbiology -- Ch 19: Omics for Antimicrobial Resistance Surveillance -- Ch 20: Total Laboratory Automation.
    Abstract: Various “omics” methods have recently revolutionized molecular diagnostics. Next-generation sequencing (NGS) makes it possible to sequence a human genome in just one day. Whole genome sequencing (WGS) greatly improves the ability to investigate the outbreaks of numerous pathogens. Metagenomics helps to analyze the microbiome, which aids greatly in identifying the pathogenesis of infectious diseases. Proteomic-based methods, namely matrix-assisted laser desorption-ionization time of flight mass spectrometry (MALDI-TOF-MS), have a promising role in identifying myctobacteria and fungi, and predicting antimicrobial resistance. While there are numerous scientific publications on “omics” applications for microbiology, there are relatively few books that review this topic from a clinical diagnostics perspective. This book looks at this field from a holistic viewpoint, instead of limiting by type of “omics” technology, in order to cover the body of knowledge needed for practitioners and academics interested in clinical and public health microbiology. Additionally, it addresses the management, economical, regulatory and operational aspects of integrating these technologies into routine diagnostics.
    Type of Medium: Online Resource
    Pages: VI, 240 p. 17 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030621551
    URL: https://doi.org/10.1007/978-3-030-62155-1
    DOI: 10.1007/978-3-030-62155-1
    DDC: 610.72
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    The Amaranth Genome (2021)
    Cham :Springer International Publishing :
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    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Genome and Transcriptome of Amaranth Species -- Chapter 2. Organelle Genomics: The Chloroplast Genome of Amaranth -- Chapter 3. Genetic and Phenotypic Odyssey: Voyage of the Grain Amaranths from the Americas to the Old World -- Chapter 4. Genetics of Betalain Pigments in Amaranth Species -- Chapter 5. Molecular Characterization of Seed Storage Proteins (SSPs) in Grain Amaranth -- Chapter 6. Genetic Diversity in Amaranth and its Close Relatives -- Chapter 7. Searching for an Identity: Functional Characterization of Taxonomically Restricted Genes in Grain Amaranth -- Chapter 8. How to Overcome Recalcitrance? Novel Strategies and Recent Advances in the Genetic Transformation of Grain Amaranth -- Chapter 9. Polyploidy and Hybridization for Amaranth Crop Improvement -- Chapter 10. Amaranth Transcription Factors in Response to Biotic and Abiotic Stresses.
    Abstract: This book describes the development of genetic resources in amaranths, with a major focus on genomics, reverse, and forward genetics tools and strategies that have been developed for crop improvement. Amaranth is an ancient crop native to the New World. Interest in amaranths is being renewed, due to their adaptability, stress tolerance, and nutritional value. There are about 65 species in the genus, including Amaranthus caudatus L., A. cruentus L., and A. hypochondriacus L., which are primarily grown as protein-rich grains or pseudocereals. The genus also includes major noxious weeds (e.g., A. palmeri). The amaranths are within the Caryophyllales order and thus many species (e.g., A. tricolor) produce red (betacyanin) or yellow (betaxanthin) betalain pigments, which are chemically distinct from the anthocyanins responsible for red pigmentation in other plants. A. hypochondriacus, which shows disomic inheritance (2n = 32; n= 466 Mb), has been sequenced and annotated with 23,059 protein-coding genes. Additional members of the genus are now also been sequenced including weedy amaranths, other grain amaranths, and their putative progenitors.
    Type of Medium: Online Resource
    Pages: XVII, 181 p. 53 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030723651
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-72365-1
    DOI: 10.1007/978-3-030-72365-1
    DDC: 580
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    Multifaceted Protocols in Biotechnology, Volume 2 (2021)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Biotechnology. ; Biomedical engineering. ; Biomedical Research. ; Biotechnology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Graviola Fruit Extraction by Ionic Liquid Microwave-assisted Extraction (IL-MAE) -- Role of Ionic Liquids in the Enzyme Stabilization: A Case Study with Trichoderma ressie Cellulase -- Role of Ionic Liquids in the Processing of Lignocellulosic Biomass -- Proliferation of rat amniotic stem cell (AFSC) on modified surface microcarrier -- Application of spectroscopic methods for the analysis of non-halal meats in food products: A narrative review -- Identification of Potential Biomarkers of Porcine Gelatin -- Gamma Ray Mutagenesis on Bacteria Isolated from Shrimp Farm Mud for Microbial Fuel Cell Enhancement and Degradation of Organic Waste -- Effect of temperature on antibacterial activity and fatty acid methyl esters of Carica papaya seed extract -- Solid-state Fermentation of Agro-industrial Waste Using Heterofermentative Lacti Acid Bacteria -- Synthesis of chitosan-folic acid nanoparticles as a drug delivery system for propolis compounds.
    Abstract: This contributed volume, “Multifaceted Protocols in Biotechnology, Volume 2”, consists of multidisciplinary methods and techniques commonly used in biotechnology studies. There are two sections covered in this book – Ionic Liquid Related Techniques & Evergreen Biotechnology Techniques. A brief introduction supports each protocol to allow easy learning and implementation. The first section consists of three chapters covering studies in modern biotechnology focusing on the role of ionic liquid techniques in extracting secondary metabolites, enzyme stabilization and biomass processing. The second section covers evergreen methodologies. It comprises five chapters covering topics on microcarrier technology for cell culture; Polymerase Chain Reaction for non-halal sources detection in food; ELISA for biomarker identification; gamma ray-induced mutagenesis for enhancing microbial fuel cells; and the effect of temperature on antibacterial activity of Carica papaya seed extract. This book will be useful to graduate students, researchers, academics, and industry practitioners working in the area of biotechnology.
    Type of Medium: Online Resource
    Pages: VII, 159 p. 45 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030755799
    URL: https://doi.org/10.1007/978-3-030-75579-9
    DOI: 10.1007/978-3-030-75579-9
    DDC: 610.72
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  • 50
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    Ovarian Cancer Biomarkers : Mapping to Improve Outcomes (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Biomedical Research. ; Medical Genetics. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. General Overview of the Origins and Pathology of Ovarian Cancer -- Chapter 2_An Introduction to the Current Management of Ovarian Cancer in the Era of Precision Oncology -- Chapter 3_The Hallmarks of Ovarian Cancer: Actionable Genetics, Targetable Pathways and Predictive Biomarkers -- Chapter 4_Genetic Alterations in Ovarian Cancer as Prognostic and Predictive Biomarkers of Therapy Response and Surgical Outcomes -- Chapter 5_The Emergence of Circulating Tumor DNA in the Management of Ovarian Cancer -- Chapter 6_Proteomic Biomarkers for Early Detection and Patients’ Stratification in Ovarian Cancer -- Chapter 7_Cutting-edge Technologies and Ovarian Cancer.
    Abstract: This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.
    Type of Medium: Online Resource
    Pages: XV, 229 p. 9 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618734
    URL: https://doi.org/10.1007/978-981-16-1873-4
    DOI: 10.1007/978-981-16-1873-4
    DDC: 610.72
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    Biomedical Translational Research : Drug Design and Discovery (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Drugs Design. ; Pharmaceutical chemistry. ; Genomics. ; Bioinformatics. ; Biomedical Research. ; Structure-Based Drug Design. ; Pharmaceutics. ; Genomics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management.
    Abstract: This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.
    Type of Medium: Online Resource
    Pages: XII, 599 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692321
    URL: https://doi.org/10.1007/978-981-16-9232-1
    DOI: 10.1007/978-981-16-9232-1
    DDC: 610.72
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    The Brassica juncea Genome (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Brassica juncea: A Crop for Food and Health -- Chapter 2. Botanical Descriptions of Brassica juncea: Taxonomy, Cytology, Cytogenetics and Phylogenetic Relationships -- Chapter 3. Chemical Composition of Oil and Cake of Brassica juncea: Implications on Human and Animal Health -- Chapter 4. Genepools of Brassica -- Chapter 5. Genetic Diversity Characterization and Population Structure in Brassica juncea -- Chapter 6. Classical Genetics and Traditional Breeding in Brassica juncea -- Chapter 7. Heteroploidy in Brassica juncea: Basics and Applications -- Chapter 8. Introgression Breeding in Brassica juncea -- Chapter 9. In vitro Culture for Micropropagation, Somatic Embryogenesis, Somatic Mutation, and Somatic Hybridization in Brassica juncea -- Chapter 10. Genetic Modification of Brassica juncea: Current Scenario and Future Prospects -- Chapter 11. Molecular Linkage Mapping in Brassica juncea: Founding the basis for Marker Assisted Selection -- Chapter 12. Brassica juncea Genome Sequencing: Structural and Functional Insights -- Chapter 13. Brassica juncea Genome Assemblies – Characteristics and Utilization -- Chapter 14. Resequencing in Brassica juncea for Elucidation of Origin and Diversity -- Chapter 15. Large Scale Genome Analysis: Genome Sequences, Chromosomal Reorganization, and Repetitive DNA in Brassica juncea and Relatives -- Chapter 16. Brassica juncea L. : Chloroplast Genome -- Chapter 17. Transcriptomics Research and Resources in Brassica spp -- Chapter 18. Metabolomics of Brassica juncea -- Chapter 19. Proteomics Approach to Uncoverkey Signaling Pathways in Brassica juncea in Abiotic and Biotic stress -- Chapter 20. Genomics Approaches to Understand the Evolution of Brassica juncea -- Chapter 21. Regulatory Genes in Development and Adaptation, and Their Utilization in Trait Improvementin Brassica juncea: Challenges and Opportunities -- Chapter 22. Advanced Molecular Breeding for Yield -- Chapter 23. Advanced Breeding for Oil and Oil Cake Quality in Brassica juncea -- Chapter 24. Advances in Breeding Strategies for Improving Stress Tolerance in Brassicas -- Chapter 25. Genome Editing in Polyploid Brassica Crops.
    Abstract: This book is the first comprehensive compilation of deliberations on elucidation and augmentation of the genome of Brassica juncea, one of the leading oilseed crops of the world, popularly called as brown mustard, Indian mustard, Chinese mustard, or Oriental mustard. It includes discussions on genepools; genetic diversity and its characterization; classical genetic and traditional breeding; basics and application of heteroploidy; techniques and applications of introgressive hybridization; in vitro culture for micro-propagation, somatic mutation, somatic embryogenesis, and somatic hybridization; genetic engineering including genetic transformation and gene silencing; and molecular genetic mapping and mapping of genes and comprehensive delineations on genome sequencing and comparative genomics; resequencing for elucidation of origin and diversity; large-scale genome analysis; plastid genome sequence; transcriptomics; metabolomics; proteomics; evolutionary genomics; role of regulatory genes in development and adaptation and their utilization in trait improvement; precise breeding for yield, quality, and resistance to biotic and abiotic stresses; and prospects of genome editing.
    Type of Medium: Online Resource
    Pages: XXXVII, 491 p. 36 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030915070
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-91507-0
    DOI: 10.1007/978-3-030-91507-0
    DDC: 580
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    Biosensors and Biochips (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biophysics. ; Senses and sensation. ; Nanoscience. ; Biotechnology. ; Biomedical Research. ; Sensory Systems. ; Nanophysics. ; Chemical Bioengineering.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Bioreceptors -- Chapter 3. Catalytic Biosensors -- Chapter 4. Affinity Biosensors -- Chapter 5. Affinity Biosensors -- Chapter 6. Label-free Biosensors -- Chapter 7. Bioreceptor Immobilization -- Chapter 8. Biochips. Chapter 9. Genome Sequencing -- Chapter 10. Genome Sequencing -- Chapter 11. Micro Electrode Arrays, Implants and Organs-on-a-Chip -- Appendix.
    Abstract: This textbook describes the basic principles and mechanism of action of biosensor systems, and introduces readers to the various types of biosensors; from affinity biosensors to catalytic, optical and label-free biosensors, the most common systems are explained in detail. Dedicated advanced sections focus on biochips and genome sequencing methods as well as organs-on-a-chip. The textbook helps readers to understand the elementary components of biosensors, and to identify and illustrate each function in the biosensor information flow, from recognition to transduction and transmission. Furthermore, readers will receive guidance in critically analyzing published studies on biosensor research, helping them to develop appropriate concepts and independently propose their own solutions. The textbook is intended for master’s students in bioengineering, biophysics, biotechnology and pharmacology that need a solid grasp of biosensor system technologies and applications, as well as students in related medical technological fields.
    Type of Medium: Online Resource
    Pages: XVIII, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030764692
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-76469-2
    DOI: 10.1007/978-3-030-76469-2
    DDC: 610.72
    Language: English
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    Pharmacovigilance for Herbal and Traditional Medicines : Advances, Challenges and International Perspectives (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Alternative medicine. ; Pharmacovigilance. ; Plant Science. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Adverse effects of herbal medicines -- Interactions between herbal and conventional medicines -- Molecular basis of herbal adverse drug reactions (ADRs) -- Detecting and assessing signals of herbal safety concerns -- Spontaneous reporting of suspected herbal ADRs: national and global perspectives -- Herbal-sector: initiated schemes for reporting herbal ADRs -- Industry and regulatory perspectives on herbal ADRs and ADR reporting -- Applying pharmacoepidemiological methods to investigating safety of herbal medicines -- Impact of traditional herbal medicinal products directive on pharmacovigilance of herbal medicines -- Communication of herbal safety concerns -- Risk management strategies for herbal medicines -- Pharmacogenomics and herbal medicines -- Nomenclature and quality of herbal medicines. .
    Abstract: This remarkable new book is the first text dedicated to the topic of pharmacovigilance for herbal and traditional medicines. Taking a truly global perspective, this volume draws together contributions from a diverse group of experts, writing on current knowledge and practices in pharmacovigilance for herbal and traditional medicines, and on advances and innovation in monitoring the safety of this unique and complex category of products and preparations. In part one, the book discusses the current status of pharmacovigilance for herbal and traditional medicines, including the importance of natural products chemistry to harms, and its relevance in considering how pharmacovigilance for these products could be undertaken. Several other chapters discuss methodological approaches and ongoing challenges in pharmacovigilance for herbal and traditional medicines, including issues relating to nomenclature, coding and classification, and the nuances involved in causality assessment. Part two of the book focusses on pharmacovigilance for herbal and traditional medicines around the world, with chapters from authors in several different countries representing diverse historical, ethnic, cultural, social and political contexts. These chapters provide deeper insights and perspectives into spontaneous reporting for herbal and traditional medicines in those countries, and in the context of the local use, practice and regulatory landscape for these products. Part two also provides an overview and new analysis of international case safety reports for herbal medicines held in VigiBase (the World Health Organization's global database of individual case safety reports, maintained by the Uppsala Monitoring Centre). This book is aimed at pharmacists, doctors, nurses and other health professionals, herbal-medicine practitioners and organisations, herbal medicine and pharmaceutical industry personnel, pharmacovigilance specialists, medicines’ regulators, health and social science researchers and academics, pharmacovigilance and health professional students, and students of herbal and traditional medicine, throughout the world. It is an extremely valuable resource for all individuals whose work touches the intersection between herbal medicines and pharmacovigilance, and it provides both an introduction to the topic and a deeper, comprehensive, contemporary account of the topic.
    Type of Medium: Online Resource
    Pages: XXII, 409 p. 22 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031072758
    URL: https://doi.org/10.1007/978-3-031-07275-8
    DOI: 10.1007/978-3-031-07275-8
    DDC: 580
    Language: English
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    Glycosignals in Cancer : Molecular Assembly and Recognition (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Life sciences. ; Cytology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Life Sciences. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: Part I. Search for novel tumor epitopes related to carbohydrates -- Chapter 1.1. The ganglioside structures: chemistry and biochemistry -- Chapter 1.2. Fucosylated proteins as cancer biomarkers -- Part II. Assembly of glycoconjugates -- Chapter 2.1. Siglec-7 and synthetic sialylpolymer -- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis -- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer -- Part III. Signaling pathways modulated by glycosylation -- Chapter 3.1. Significance of FUT8in pancreatic cancer and others -- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells -- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules -- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells -- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction -- Part V. Clinical trials targeting glycosignals -- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.
    Abstract: This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
    Type of Medium: Online Resource
    Pages: VI, 238 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811977329
    URL: https://doi.org/10.1007/978-981-19-7732-9
    DOI: 10.1007/978-981-19-7732-9
    DDC: 610.72
    Language: English
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    Progress in Heritable Soft Connective Tissue Diseases (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Physiology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Physiology. ; Internal Medicine.
    Description / Table of Contents: Basic structure, physiology and biochemistry of connective tissues and extracellular matrix collagens -- Tendon Extracellular Matrix Assembly, Maintenance and Dysregulation Throughout Life -- Basic Components of Connective Tissues and Extracellular Matrix: Fibronectin, Fibrinogen, Laminin, Elastin, Fibrillins, Fibulins, Matrilins, Tenascins and Thrombospondins -- Proteoglycans and Diseases of Soft Tissues -- Growth Factor Roles in Soft Tissue Physiology and Pathophysiology -- Connective Tissue Disorders and Cardiovascular Complications: The Indomitable Role of Transforming Growth Factor-β Signaling -- The Pathophysiology and Pathogenesis of Marfan Syndrome -- Ehlers-Danlos syndromes, joint hypermobility and hypermobility spectrum disorders -- Ehlers–Danlos Syndrome Associated with Glycosaminoglycan Abnormalities -- Loeys-Dietz Syndrome -- Meester-Loeys syndrome -- Clinical and Molecular Delineation of Cutis Laxa Syndromes: Paradigms for Elastic Fiber Homeostasis -- Collagen VI Muscle Disorders: Mutation Types, Pathogenic Mechanisms and Approaches to Therapy -- Connective Tissue Disorders in Domestic Animals.
    Abstract: This volume represents a substantially revised and updated 2nd edition of a reference handbook on major structural components of soft connective tissues and a whole slew of heritable diseases of soft connective tissues. The number of clearly identifiable and distinct disorders has grown somewhat since the 1st edition in 2014, e.g., Ehlers-Danlos syndrome has now 13 entities. A brand new syndrome, Meester Loeys syndrome carrying the name of Bart Loeys was added as a companion to Loeys-Dietz syndrome. Numerous variations of cutis laxa and joint mobility disorders have been discovered taking advantage of recent advancements in genetic analysis. We have acquired better understanding of pathogenesis and biochemical changes in some other, more established entities, such as Marfan and collagen VI myopathies where better management and possible treatment are on the horizon. Even in the case of connective tissue diseases in domestic animals some progress has been made. All these updates were contributed by a group of distinguished and preeminent physicians and scientists, all of them not just working in the field but making new discoveries described by them. Readers will notice that seemingly there is an overlap among many of these disorders. And indeed, many of them, if not most are interconnected because of the prominent roles of TGFβ, of fibrillin microfibrils and collagen fibril assembly (and other molecules) playing in connective tissues physiology, and by extension in pathogenesis of many disorders described in the book. What I found particularly helpful that author(s) of each chapter bring their own perspective even when described closely related mechanism of the disease. These observations should help with diagnosis and management of such cases. The first chapters are more general, concentrating more on the physiology, structure and biochemistry of normal soft tissues. That should help in better understanding of the pathophysiology. Last but not least, the chapters are very readable, more like detective stories than dry description of genetic/biochemical defects. I do hope that basic scientists and clinicians with similar and diverse interests alike will appreciate this volume and will be inspired by it to develop their research in the field.
    Type of Medium: Online Resource
    Pages: IX, 343 p. 1 illus. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030806149
    Series Statement: Advances in Experimental Medicine and Biology, 1348
    URL: https://doi.org/10.1007/978-3-030-80614-9
    DOI: 10.1007/978-3-030-80614-9
    DDC: 610.72
    Language: English
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    The Moso Bamboo Genome (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Economic Value and Research Significance of Moso Bamboo -- Chapter 2. Moso Bamboo Germplasm Resources in China/World -- Chapter 3. Biological Traits of Moso Bamboo -- Chapter 4. Moso Bamboo Genome -- Chapter 5. Moso Bamboo Transposon -- Chapter 6. Transcriptome of Moso Bamboo -- Chapter 7. Moso Bamboo Alternative Splicing (AS ) and Polyadenylation -- Chapter 8. Characterizations and Function of Transcript Factor Gene families -- Chapter 9. MicroRNAs of Moso Bamboo -- Chapter 10. Mitochondrial Genome of Endophytic Fungi from the Seed of Moso Bamboo -- Chapter 11. Breeding Strategies of Moso Bamboo.
    Abstract: This book is the first comprehensive compilation describing the botanical traits, genetic resources, whole genome sequencing, Mitochondrial genome, transcriptomes of different organs with developmental stages, transcription factors, delineating gene evolution of gene family in Bambusoideae, alternative splicing (AS) and polyadenylation, case studies for economically important traits such as internode length, shoot fast growing, flowering, ageing and stress-resistant genes and small RNAs-mediated gene regulation of moso bamboo flowering and other developmental stages. Applications of transcriptome and genome approaches in moso bamboo in general and the prospects of transgenic breeding and genome editing technologies in bamboo are also discussed. Altogether, the book comprises eleven chapters covered over 200 pages authored by the researchers involved in genomic science, molecular biology, and breeding. This book appeals to graduate students, post-graduate students, research scholars, researchers, and industry players in the field of plantation bamboo in general, bamboo processing and bamboo garden owner and fans of bamboo culture in particular.
    Type of Medium: Online Resource
    Pages: XXII, 208 p. 124 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030808365
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-80836-5
    DOI: 10.1007/978-3-030-80836-5
    DDC: 580
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    Latin American Blackberries Biology : Mora de Castilla (Rubus glaucus Benth.) Vol 1 (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Botany. ; Agriculture. ; Biomolecules. ; Physical biochemistry. ; Macromolecules. ; Plant Science. ; Agriculture. ; Structural Biology.
    Description / Table of Contents: 1. Introduction -- 2. Floral morphology and phenology -- 3. Pollen grain morphology, viability, and insect visitation -- 4. The phenology of Rubus glaucus Benth. characterized by the BBCH scale -- 5.Propagation and cultivation -- 6.Fruit and chromosome number -- 7.Post-harvest physiology and nutritional facts -- 8.Genetic diversity -- 9.Breeding programs -- 10.Morphological diversity -- 11.Rubus glaucus and climate change.
    Abstract: The current book focuses on Mora de Castilla (Rubus glaucus Benth.). It explores aspects, such as origin, phenology, propagation, floral and fruit morphology, arthropod visitors, pollination mechanisms, propagation methods, chromosome number, fruit development, breeding, morphological diversity, and the impact of climate change. It includes novel data about plant phenology, flowering, insect visitors, seed germination, fruit morphology, and allometric relationships. This work includes an in-depth review of the most recently published information on the topic. Mora de Castilla is an economically important fruit crop from the Andes. It has been crossed with other Rubus species due to its high yield and everbearing habit. Currently, it is an economically important plant. It has been hybridized with other Rubus species producing new and better-quality hybrids This book contains numerous photographs selected by the author to provide the reader with detailed information about the plant´s morphological features and arthropod visitors. .
    Type of Medium: Online Resource
    Pages: XVIII, 178 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031317507
    URL: https://doi.org/10.1007/978-3-031-31750-7
    DOI: 10.1007/978-3-031-31750-7
    DDC: 580
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    Biomes of the Southern Hemisphere (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Botany. ; Ecology . ; Biodiversity. ; Biotic communities. ; Population biology. ; Plant Science. ; Ecology. ; Biodiversity. ; Community and Population Ecology.
    Description / Table of Contents: 1 -- Introduction -- 2. Southern tropical and subtropical rainforests -- 3. Multi-faced southern seasonal tropics 3.1 Heterogeneity of the savanna biomes: a southern perspective -- 4. Southern mediterranean: an extratropical plant marvel -- 5. Dry face of the ‘wet hemisphere’: southern deserts and semideserts -- 6. Austral temperate forests: a biome-classification conundrum -- 7. Southern ‘steppes’ and other grassy oddballs -- 8. The biomes of the coldest corners of the World -- 9. Synthesis: A New Global Zonobiome System -- 10. Further Challenges and Research Agenda -- References.
    Abstract: This is the first comprehensive and critical evaluation of the biome (large-scale, functional biotic communities) patterns in the Southern Hemisphere. Revising the Heinrich Walter's zonobiome system for the Southern Hemisphere appeared as necessary because of the bioclimatic imbalance between the Hemispheres. This revision resulted in formulation of a new zonobiome system, considering the geographic peculiarities of both Hemispheres, hence creating a new, powerful tool of global nature-resource survey and conservation. The system has a potential to attract the interest of the global climate modeling community as the concept of biome (and associated hierarchical system) has a strong functional focus. All zonal biomes of the Southern Hemisphere are featured, and the major challenges we face in understanding their origins, structure, and functioning are discussed. The book contains a wealth of original data resulting from collation of bioclimatic data and vegetation mapping.
    Type of Medium: Online Resource
    Pages: XIV, 219 p. 71 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031267390
    Series Statement: Biome Ecology, 1
    URL: https://doi.org/10.1007/978-3-031-26739-0
    DOI: 10.1007/978-3-031-26739-0
    DDC: 580
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    Biodiesel from Flowering Plants (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Anatomy. ; Biotechnology. ; Plant Science. ; Anatomy. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. History of Biodiesel -- Chapter 3. Anacardiaceae -- Chapter 4. Apocynaceae -- Chapter 5. Arecaceae -- Chapter 6. Asteraceae -- Chapter 7. Betulaceae -- Chapter 8. Brassicaceae -- Chapter 9. Caryocaraceae -- Chapter 10. Chrysobalanaceae -- Chapter 11. Clusiaceae -- Chapter 12. Combretaceae -- Chapter 13. Compositae -- Chapter 14. Cornaceae -- Chapter 15. Cucurbit -- Chapter 16. Cyperaceae -- Chapter 17. Dipterocarpaceae -- Chapter 18. Euphorbiaceae -- Chapter 19. Fabaceae -- Chapter 20. Irvingiaceae -- Chapter 21. Linaceae -- Chapter 22. Magnoliaceae -- Chapter 23. Malvaceae -- Chapter 24. Meliaceae -- Chapter 25. Nyssaceae -- Chapter 26. Oleaceae -- Chapter 27. Papavaraceae -- Chapter 28. Pedaliaceae -- Chapter 29. Poaceae -- Chapter 30. Putranjivaceae -- Chapter 31. Rosaceae -- Chapter 32. Rutaceae -- Chapter 33. Salicaceae -- Chapter 34. Salvadoraceae -- Chapter 35. Sapindaceae -- Chapter 36. Sapotaceae -- Chapter 37. Schisandraceae -- Chapter 38. Simaroubaceae -- Chapter 39. Simmondsiaceae -- Chapter 40. Solanaceae -- Chapter 41. Sterculiaceae -- Chapter 42. Theaceae -- Chapter 43. Zygophyllaceae -- Chapter 44. Catalyst for Transesterification -- Chapter 45. Standards for Biodiesel.
    Abstract: This book offers an exhaustive coverage of process modifications in biodiesel production from oil drawn from 84 oleaginous plant species occurring in all parts of the world, thereby enlisting the scope and potential of many new and non-conventionally obscure plant sources. Biodiesel, now prepared from major vegetable oils, has become a compulsion to offset the dwindling reserve of petro-diesel, which naturally intrudes into the cooking oil demand. This has necessitated search for new sources. The book consolidates the biodiesel production from oils being extracted from conventional plants and also from a plethora of new and non-conventional plants along with their habit and habitats, history of biodiesel’s invention, explanation on species-wise biodiesel process variables, catalytic inclusions, global standards, fuel properties varying with species, blending benefits, cost effectiveness, shelf life, ignition characteristics, fuel consumption and engine performances with eco-friendly exhaust. This book is of immense use to teachers, researchers, scientists of climatology and carbon footprint, energy consultants, fuel chemists, students of agriculture and forestry, automobile engineering, industrial chemistry, environmental sciences and policy makers or anyone who wishes to scale up the biodiesel industry.
    Type of Medium: Online Resource
    Pages: XXIV, 675 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647758
    URL: https://doi.org/10.1007/978-981-16-4775-8
    DOI: 10.1007/978-981-16-4775-8
    DDC: 580
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    The Citron Compendium : The Citron (Etrog) Citrus medica L.: Science and Tradition (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Judaism. ; Religion and science. ; Arts. ; Plant Science. ; Judaism. ; Religion and Sciences. ; Arts.
    Description / Table of Contents: The Biology of the Citron -- Citron Genomics -- Citron Phytochemistry -- Selected Aspects of Commercial Production in Etrog Orchards -- Preserving Etrog Quality After Harvest: Doctrine and Practice -- Citron Arthropod Pests in the Mediterranean, Their Origin and Notes On Their Biology and Management -- Diseases of the Etrog Citron and Other Citrus Trees -- The Citron ( Citrus medica L.) in China -- The Citron in Italy and Its cultivation in Calabria -- The Citron in Corsica -- The Citron in the United States -- The Citron in Mediterranean Food and Beverages -- 'Fruit of the Goodly Trees’: The Talmudic Discourse on the Etrog Citron -- From Theophrastus to the Present: The Citron in Medicine -- The Etrog Citron in Art -- The Etrog Citron in Midrashic and Kabbalistic Literature -- From ‘An Etrog’ to ‘One's Etrog’: A Literary Analysis of S.Y. Agnon’s Story -- History of the Citron in Ancient Israel and the Near East -- The Etrog Citron Trail to the North: Genoa and Trieste -- The Corfu Etrog Citron Polemic -- The Grafted Etrog Citron Controversy -- Etrog Citrons of the Land of Israel in Modern Times.
    Abstract: This comprehensive book covers the theoretical and practical aspects of citron trees and fruit. The citron (Citrus medica L.), one of the three primary species ancestral to most citrus types, is used for traditional medicine and is highly revered in the Jewish religion during the Tabernacles feast, referred to by the name 'Etrog'. This book’s three sections address biology (botany, genomics, Chinese and Mediterranean citrons, diseases, pests, and horticulture), tradition (Talmudic discourse, mysticism, medicine, literature, art, food, and beverages) and history (archaeology, trade, grafting controversies); these sections are supplemented by a glossary and pictorial album. The 22 chapters, some new and some translated and considerably expanded from the 2018 Hebrew edition, were written by world-renowned specialists from Israel, Italy, France, the U.S.A., China and Australia. The book is written in an accessible scientific style aimed at a wide range of readers. .
    Type of Medium: Online Resource
    Pages: XVIII, 607 p. 228 illus., 196 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031257759
    URL: https://doi.org/10.1007/978-3-031-25775-9
    DOI: 10.1007/978-3-031-25775-9
    DDC: 580
    Language: English
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    Plant-Based Therapeutics, Volume 1 : Cannabis sativa (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Alternative medicine. ; Pharmacology. ; Medicinal chemistry. ; Physiology. ; Agriculture. ; Plant Science. ; Complementary and Alternative Medicine. ; Pharmacology. ; Medicinal Chemistry. ; Physiology. ; Agriculture.
    Description / Table of Contents: Chapter 1 The History of Cannabis -- Chapter 2 The Bioactive Components of Plants -- Chapter 3 Chemical Constituents of Cannabis -- Chapter 4 The Bioactive Components of Cannabis -- Chapter 5 Neurological Effects of Cannabis -- Chapter 6 Psychotropic Effects of Cannabis -- Chapter 7 The Analgesic effects of Cannabis -- Chapter 8 Cannabis and Perinatal Development -- Chapter 9 Cannabis and Multiple Sclerosis -- Chapter 10 Cannabis and Cancer -- Chapter 11 Cannabis and Parkinson’s disease -- Chapter 12 Cannabis and the Skin -- Chapter 13 Antiviral Activities of Cannabis -- Chapter 14 Alkaline Phosphatase Stimulation.
    Abstract: By examining historical applications of the compounds found in plants, this five-volume series serves as a reference for quality assurance, research, product development, and regulatory guidance of the compounds found in plant-based medicines. This work supports the growing consumers' interest in herbal medicine for wellness and health. Plant-Based Therapeutics, Volume 1: Cannabis sativa, the first in the series, covers a unique plant species and provides the framework to integrate its evidence-based scientific discoveries with healthcare therapies. Cannabis has been used in religious ceremonies and medical purposes for thousands of years. Cannabidiol (CBD), the main non-psychoactive component of Cannabis, was isolated in the 1940s, and its structure was established in the 1960s. In 1964 tetrahydrocannabinol (THC), the psychoactive component, was isolated. Cannabis has more than 500 components, of which 104 cannabinoids have been identified. Two of them, THC and CBD, have been the primary components of scientific investigations. They were approved by the FDA for chemotherapy-induced nausea and vomiting in 1985; for appetite stimulation in wasting conditions, such as AIDS, in 1992, and in 2018 for treating two forms of pediatric epilepsy, Dravet syndrome and Lennox-Gastaut syndrome. Beyond the indications for which cannabinoids are FDA-approved, the evidence reveals that cannabinoid receptors are present throughout the body, embedded in cell membranes, and are believed to be more numerous than any other receptor system. When cannabinoid receptors are stimulated, a variety of physiologic processes ensue. Thus, other constituents of Cannabis are extremely promising either as individual compounds or their potential synergistic or entourage effects in the treatment of numerous medical conditions. .
    Type of Medium: Online Resource
    Pages: XXI, 657 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031351556
    URL: https://doi.org/10.1007/978-3-031-35155-6
    DOI: 10.1007/978-3-031-35155-6
    DDC: 580
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    Basic Organic Chemistry for the Life Sciences (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Life sciences. ; Chemistry, Organic. ; Enzymology. ; Biochemistry. ; Biomedical Research. ; Life Sciences. ; Organic Chemistry. ; Enzymology. ; Biochemistry.
    Description / Table of Contents: 1. Alkanes, composition, constitution, and configuration -- 2. Functional groups -- 3. Electronic structure of organic molecules -- 4. Alkenes and alkynes -- 5. Substitutions on saturated carbon atom -- 6. Nucleophilic additions -- 7. Stereochemistry, symmetry, and molecular chirality -- 8. Derivatives of carboxylic acids -- 9. Electrophilic substitutions -- 10. Pericyclic reactions -- 11. Organic natural products -- 12. Organic supramolecular and supermolecular structures.
    Abstract: This textbook is designed for students of biology, molecular biology, ecology,medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions.
    Type of Medium: Online Resource
    Pages: XV, 205 p. 339 illus., 114 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030924386
    URL: https://doi.org/10.1007/978-3-030-92438-6
    DOI: 10.1007/978-3-030-92438-6
    DDC: 610.72
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    Genomic Designing for Abiotic Stress Resistant Oilseed Crops (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Genomic Designing For Abiotic Stress Tolerant Soybean -- Designing the Rapeseed Genome for Abiotic Stress Tolerance -- Sunflower and Abiotic Stress: Genetics and Breeding for Resistance in the Post-Omics Era -- Integration of Genomics Approaches in Abiotic Stress Tolerance in Groundnut (Arachis hypogaea L.): An overview -- Drought Tolerance in Rape and Mustard: Conventional and Molecular Approaches -- Genomic Designing For Sesame Resistance To Abiotic Stresses -- Abiotic Stresses in Castor Plant -- Designing Genomic Solutions to Enhance Abiotic Stress Resistance in Flax.
    Abstract: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in oilseed crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The eight chapters each dedicated to a oilseed crop in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Type of Medium: Online Resource
    Pages: XXIII, 283 p. 18 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030900441
    URL: https://doi.org/10.1007/978-3-030-90044-1
    DOI: 10.1007/978-3-030-90044-1
    DDC: 580
    Language: English
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    Food Packaging: The Smarter Way (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Food science. ; Nanotechnology. ; Biomedical Research. ; Food Science. ; Food Engineering. ; Food Nanotechnology.
    Description / Table of Contents: Chapter 1. Chapter 1. Food packaging industry - An introduction -- Chapter 2. Toward Smarter Food Packaging -- Chapter 3. Novel packaging development, assessment and authentication using smart technologies, non-invasive biometric sensory tools, and artificial intelligence -- Chapter 4. Biodegradable packaging materials and techniques to improve their performance -- Chapter 5. Smart Freshness Indicator for Animal Based Products Packaging - Current Status.-Chapter 6. Packaging of dairy products-Emerging strategies -- Chapter 7. Functional packaging materials for fishery products applications -- Chapter 8. Edible films and coatings: Major challenges and potential applications in food Packaging: A Review.-Chapter 9. Role of sensors to improve food/beverage packaging -- Chapter 10. Functional nanomaterials for food packaging applications -- Chapter 11. Rules and regulations related with packaging.
    Abstract: This book reviews the science and technology of food packaging and covers the potential innovations in the food packaging sector. At the same time, it highlights the issues and prospects for linking the laboratory research to the market. In addition to typical packaging requirements such as food quality, shelf life, protection, communication, and marketing, the book emphasizes the need for novel packaging materials, including biodegradable packaging for a variety of food products. A wide range of food products has been kept in focus and includes animal-based food products such as dairy products and sea foods. The book presents the next level of packaging solutions i.e., smart packaging with the applications of potential tools such as intelligent and active packaging, and includes the latest research on emerging digital technologies for packaging development, assessment, and acceptability. It further highlights the strategies including blends, reinforcing agents, cold plasma, UV light applications, chemical, and enzymatic methods and explores the new opportunities leading to improvement in the packaging performance. Smart freshness indicator applications, including gas and time-temperature indicators for quality and safety of packaged products, have been covered in detail. The book also includes the functional characteristics of edible films and coatings, including their bioactive characteristics. Finally the book presents the rules and regulation related to packaging.
    Type of Medium: Online Resource
    Pages: XI, 286 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811671968
    URL: https://doi.org/10.1007/978-981-16-7196-8
    DOI: 10.1007/978-981-16-7196-8
    DDC: 610.72
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    Coronavirus Therapeutics – Volume II : Clinical Management and Public Health (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Virology. ; Clinical medicine Research. ; Epidemiology. ; Public health. ; Biomedical Research. ; Virology. ; Clinical Research. ; Epidemiology. ; Public Health.
    Description / Table of Contents: Clinical features, diagnostic evaluation and management of COVID-19 patients -- Outbreak of COVID-19: A Detailed Overview and Its Consequences -- A paradigm gap in host-pathogen interaction studies: Lesson from the COVID-19 pandemic -- SARS/CoV-2: Behavioral Host Manipulation -- Management of COVID-19 in the Intensive Care Unit -- First wave of Covid-19 pandemic in Italy: data and evidence -- Risk factors for COVID-19: diabetes, hypertension and obesity -- Current challenges for the effective management of the COVID-19 pandemic -- COVID-19 Outbreak Challenges in Indian Migrant Pregnant and Lactating Mothers: Learnt Lesson Demands Phronesis and Hierarchical Strategies for Such Future Pandemics -- COVID-19 and Extracorporeal Membrane Oxygenation -- COVID-19's Clinical-Pathological Evidence in Relation to its Repercussion on the Central and Peripheral Nervous System -- Anatomopathological Aspects and Clinical Correlation of COVID-19: A Systematic Review -- SARS-CoV-2 liability: the hidden mystery behind its presentation in children.
    Abstract: The book Coronavirus Therapeutics Volume II provides the most comprehensive review on contemporary knowledge on the consequences during the outbreak of Coronavirus. This also describes the clinical features, diagnostic evaluation and management of Coronavirus patients. Using an integrative approach to the understanding of paradigm gap in host-pathogen interaction studies to the management of Coronavirus patients in the Intensive Care Unit to the current challenges for the effective management of Coronavirus pandemic risk factors including diabetes, hypertension, obesity and repercussion on the central and peripheral nervous system. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 241 p. 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851132
    Series Statement: Advances in Experimental Medicine and Biology, 1353
    URL: https://doi.org/10.1007/978-3-030-85113-2
    DOI: 10.1007/978-3-030-85113-2
    DDC: 610.72
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    Coronavirus Therapeutics – Volume I : Basic Science and Therapy Development (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Virology. ; Clinical medicine Research. ; Epidemiology. ; Biomedical Research. ; Virology. ; Clinical Research. ; Epidemiology.
    Description / Table of Contents: Origin and structural biology of Novel Coronavirus (SARS-CoV-2) -- The Molecular Virology of Coronaviruses with Special Reference to SARS-CoV-2 -- Epidemiology, transmission and molecular immunopathology of SARS-CoV-2 -- Epidemiology and Etiopathogeny of Covid-19 -- Immunological and Hematological Response in COVID-19 -- Toll-like receptors (TLRs) as Therapeutic Targets for Treating SARS-CoV-2: An Immunobiological Perspective -- Potential drug strategies to target Coronaviruses -- Possible therapeutic intervention strategies for COVID-19 by manipulating the cellular proteostasis network -- The potential impact of statins in the treatment of patients with COVID-19 infection -- Anticoronavirus activity of water-soluble pristine C60 fullerenes: in vitro and in silico screening -- Application of Nanoscale materials and nanotechnology against viral infection: A special focus on Coronaviruses -- Obesity: A Risk Factor for Covid-19 -- Cytokine Storm and Failed Resolution in COVID-19: Taking Cue from Multiple Sclerosis.
    Abstract: The book Coronavirus Therapeutics Volume I provides the most comprehensive review on contemporary knowledge on the origin, structural biology and molecular aspects of Coronaviruses. It also describes the etiology and pathogeny and therapeutic targets including vaccine drug candidates against Coronaviruses in the light of current scientific knowledge. Using an integrative approach to the understanding of Coronaviruses structure, function and immunobiology, the contributors provide a synopsis of novel mechanisms by which Coronaviruses can be treated. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 222 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851095
    Series Statement: Advances in Experimental Medicine and Biology, 1352
    URL: https://doi.org/10.1007/978-3-030-85109-5
    DOI: 10.1007/978-3-030-85109-5
    DDC: 610.72
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    Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID-19 (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Biochemical markers. ; Proteins. ; Metabolism. ; Genomics. ; Biomarkers. ; Proteins. ; Metabolism. ; Genomics.
    Description / Table of Contents: Chapter 1. The COVID-19 Pandemic: SARS-CoV-2 Structure, Infection, Transmission, Symptomology and Variants of Concern -- Chapter 2. Long-term Vaccination and Treatment Strategies for COVID-19 Disease and Future Coronavirus Pandemics -- Chapter 3. Consequences of the Lockdown - Domestic Violence during the COVID-19 Pandemic -- Chapter 4. Psychological distress impact of Coronavirus disease (COVID-19) outbreak on three continents: A systematic review and meta-analysis -- Chapter 5. A Molecular Biomarker-based Triage Approach for Targeted Treatment of Post-COVID-19 Syndrome Patients with Persistent Neurological or Neuropsychiatric Symptoms -- Chapter 6. Genetic Associations with Coronavirus Susceptibility and Disease Severity -- Chapter 7. COVID Diagnostics: from Molecules to Omics -- Chapter 8. Assessing Biomarkers in Viral Infection -- Chapter 9. Proteomic Investigation of COVID-19 Severity During the Tsunamis Second Wave in Mumbai -- Chapter 10. NMR-Metabolomics in COVID-19 Research -- Chapter 11. Potential Biomarkers of Mitochondrial Dysfunction Associated with COVID-19 Infection -- Chapter 12. Red Cell Distribution Width as a Prognostic Indicator for Mortality and ICU Admission in Patients with COVID-19 -- Chapter 13. Predicting the COVID-19 Patients Status using Chest CT Scan Findings: A Risk Assessment Model Based on Decision Tree Analysis -- Chapter 14. Inferring Recombination Events in SARS-CoV-2 Variants In Silico -- Chapter 15. Amplicon-based Nanopore Sequencing of Patients Infected by the SARS-CoV-2 Omicron (B.1.1.529) Variant in India -- Chapter 16. Perspectives on Rapid Antigen Tests for Downstream Validation and Development of Theranostics -- Chapter 17. Machine Learning and COVID-19: Lessons from SARS-CoV-2 -- Chapter 18. The Relationship between Psoriasis, COVID-19 Infection and Vaccination during Treatment of Patients -- Chapter 19. Immunogenicity of Inactivated SARS-CoV-2 Vaccine (BBIBP-CorV; Sinopharm) and Short-term Clinical Outcomes in Vaccinated Solid Organ Transplant Recipients: A Prospective Cohort Study -- Chapter 20. Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective -- Chapter 21. Antiviral Mechanisms of Curcumin and its Derivatives in Prevention and Treatment of COVID-19: A review -- Chapter 22. Evaluation of Curcumin-Piperine Supplementation in COVID-19 Patients Admitted to the Intensive Care: A Double-Blind, Randomized Controlled Trial -- Chapter 23. Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases of COVID-19: A Hypothetical Approach -- Chapter 24. The Potential Effect of Royal Jelly on Biomarkers Related to COVID-19 Infection and Severe Progression -- Chapter 25. Statins: Beneficial Effects in Treatment of COVID-19 -- Chapter 26. Multiplex Immunoassay Approaches Using Luminex® xMAP® Technology for the Study of COVID-19 Disease -- Chapter 27. Rapid Detection of SARS-CoV-2 Variants of Concern by Genomic Surveillance Techniques.
    Abstract: The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.
    Type of Medium: Online Resource
    Pages: XI, 513 p. 87 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031280122
    Series Statement: Proteomics, Metabolomics, Interactomics and Systems Biology, 1412
    URL: https://doi.org/10.1007/978-3-031-28012-2
    DOI: 10.1007/978-3-031-28012-2
    DDC: 610.72
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    Baccharis : From Evolutionary and Ecological Aspects to Social Uses and Medicinal Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Ecology . ; Conservation biology. ; Botanical chemistry. ; Plant physiology. ; Pharmacology. ; Plant Science. ; Ecology. ; Conservation Biology. ; Plant Biochemistry. ; Plant Physiology. ; Pharmacology.
    Description / Table of Contents: Part I: Ecological and Evolutionary pathways -- Chapter 1: The Ecological and Applied Potential of Baccharis -- Chapter 2: Baccharis: Diversity and Distribution -- Chapter 3: The Evolution of Genetic Studies of Baccharis -- Chapter 4: Intersexual Differences in Demography, Resource Investment, and Herbivory in Baccharis -- Chapter 5: Multitrophic and Indirect Interactions in the Baccharis dracunculifolia System -- Chapter 6: Endophytic Fungi of Baccharis -- Chapter 7: Baccharis as Nurse Plants -- Chapter 8: Biological Invasion by Baccharis -- Part II: Structure and Chemistry of Baccharis -- Chapter 9: Morpho-anatomical Characteristics of Species of Baccharis -- Chapter 10: Essential Oils of Baccharis: Chemical Composition and Biological Activities -- Chapter 11: Flavonoids of Baccharis -- Chapter 12: Chemistry and Biological Activities of Phenolic Compounds from Baccharis Genus -- Chapter 13: Baccharis Terpenoid Compounds -- Chapter 14: Macrocyclic Trichothecenes of Baccharis -- Chapter 15: Livestock Intoxication by Baccharis -- Part III: Baccharis: Applications and Innovations -- Chapter 16: An Overview of the Cultural and Popular Use of Baccharis -- Chapter 17: CPQBA 1: First Cultivar Registered and Protected From a Brazilian Medicinal Plant -- Chapter 18: Perspectives of Baccharis Secondary Metabolites as Sources for New Anticancer Drug Candidates -- Chapter 19: Innovation and Knowledge of Prospective Studies on the Genus Baccharis -- Part IV: Propolis of Baccharis -- Chapter 20: Chemical Constituents and Antioxidant Properties of Green Propolis -- Chapter 21: Possible Role of Propolis-derived Components in the Prevention and Treatment of Obesity and Diabetes -- Chapter 22: Effects of the Green Propolis on the Immune Response -- Chapter 23: From Innovation to Market: an Analysis of the Propolis Production Chain.
    Abstract: This book has a broad scope and provides a comprehensive overview of the most up-to-date knowledge of the plant genus Baccharis. The book is organized into four major topics encompassing the evolution, ecology, chemistry, as well as environmental and medical applications of the genus. This publication is a major reference for an audience of practising researchers, academics, PhD students, and other scientists in a wide-ranging collection of fields, from Sociology to Medicine to bioeconomy.
    Type of Medium: Online Resource
    Pages: XIX, 578 p. 137 illus., 79 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030835118
    URL: https://doi.org/10.1007/978-3-030-83511-8
    DOI: 10.1007/978-3-030-83511-8
    DDC: 580
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    Targets of Cancer Diagnosis and Treatment : Ion Transport in Tumor Biology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Internal medicine. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Internal Medicine. ; Physiology.
    Description / Table of Contents: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges -- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer -- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk -- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics -- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research -- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions -- Ion Transport and Radioresistance -- Ion Transporting Proteins and Cancer: Progress and Perspectives.
    Abstract: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges Alina L. Capatina, Dimitris Lagos, and William J. Brackenbury Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk Jerry J. Fan and Xi Huang Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu Ion Transport and Radioresistance Bastian Roth and Stephan M. Huber Ion Transporting Proteins and Cancer: Progress and Perspectives Mustafa B. A. Djamgoz.
    Type of Medium: Online Resource
    Pages: X, 277 p. 30 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031039942
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 183
    URL: https://doi.org/10.1007/978-3-031-03994-2
    DOI: 10.1007/978-3-031-03994-2
    DDC: 610.72
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    Fundamentals of Field Crop Breeding (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Agriculture. ; Genetics. ; Biotechnology. ; Plant Science. ; Agriculture. ; Genetics and Genomics. ; Biotechnology.
    Description / Table of Contents: Chapter 1: Breeding Field Crops – History, Current Status And Introspections -- Chapter 2: Wheat Breeding -- Chapter 3: Rice Breeding -- Chapter 4: Maize Breeding -- Chapter 5: Barley Breeding -- Chapter 6: Pearl Millet Breeding. Chapter 7: Sorghum Breeding. Chapter 8: Small Millets Breeding -- Chapter 9: Sugarcane Breeding -- Chapter 10: Jute Breeding -- Chapter 11: Cotton Breeding -- Chapter 12: Maintenance Breeding Of Pusa Basmati Varieties -- Chapter 13: Maintenance Breeding -- Chapter 14: Efficient Breeding Of Crop Plants -- Chapter 15: Brassica Breeding -- Chapter 16: Groundnut Breeding -- Chapter 17: Soybean Breeding -- Chapter 18: Castor Breeding -- Chapter 19: Sunflower Breeding -- Chapter 20: Chickpea Breeding -- Chapter 21: Pigeonpea Breeding -- Chapter 22: Mungbean Breeding -- Chapter 23: Urdbean Breeding -- Chapter 24: Lentil Breeding -- Chapter 25: Fieldpea Breeding -- Chapter 26: Lathyrus Breeding.
    Abstract: This book is an advanced textbook and a reference book for the post-graduate plant-breeding students and the plant breeders. It consolidates fundamental concepts and also the latest advances in plant-breeding practices including development in crop genomics. It contains crop wise explanation on origin, reproduction, genetics of yield contributing traits, biotic and abiotic stresses, nutritional improvement and crop specific plant-breeding procedures and techniques. The chapters are planned to describe crop-focused breeding procedure for the major crop plants as per their economic importance. The recent developments in breeding of field crops have been reported. The recent progress made in mapping traits of economic importance has been critically reviewed for each crop. The progress made in markers assisted selected in few crops has been summarized. This book bridges the knowledge gap and bring to the researchers and students information on modern breeding tools for developing biotic and abiotic stress tolerant, climate resilient and micronutrient rich varieties of field crops. The chapters in book are contributed by experienced Plant Breeders.
    Type of Medium: Online Resource
    Pages: XIV, 1389 p. 109 illus., 98 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692574
    URL: https://doi.org/10.1007/978-981-16-9257-4
    DOI: 10.1007/978-981-16-9257-4
    DDC: 580
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    Managing Landscapes for Change (2020)
    Cham :Springer International Publishing :
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    Keywords: Human geography. ; Environmental management. ; Agriculture. ; Physical geography. ; Energy policy. ; Energy and state. ; Human Geography. ; Environmental Management. ; Agriculture. ; Physical Geography. ; Energy Policy, Economics and Management.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. What is a Landscape? -- Chapter 3. Drivers of Landscape Change -- Chapter 4. Landscape Trajectories -- Chapter 5. Options for Managing Landscape for Change -- Chapter 6. Barriers to Managing for Change -- Chapter 7. Social and Institutional Innovations -- Chapter 8. Technologies for Innovating Forward -- Chapter 9. Conclusions and Recommendation.
    Abstract: This book discusses how future landscapes will be shaped by pervasive change and where, when, and how society should manage landscapes for change. Readers will learn about the major anthropogenic drivers of landscape change, including climate change and human induced disturbance regimes, and the unique consequences that multiple and simultaneously occurring change agents can have on landscapes. The author uses landscape trajectories as a guide to selecting the appropriate course of action, and considers how landscape position, inertia, and direction will determine landscape futures. The author introduces the concept of landscapes as socio-technical-ecological systems (STES), which combines ecological and technological influences on future landscape change and the need for society to acknowledge both when considering landscape management. Thinking beyond solutions, the author identifies barriers to managing landscapes for change including the cost, cultural identity of local populations, and the fear of taking action under uncertain conditions. Nevertheless, processes, tools, and technologies exist for overcoming social and ecological barriers to managing landscapes for change, and continued investment in social and scientific infrastructure holds out hope for maintaining our landscape values even as we enter an era of unprecedented change and disruption.
    Type of Medium: Online Resource
    Pages: XI, 111 p. 36 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030620417
    Series Statement: Landscape Series, 27
    URL: https://doi.org/10.1007/978-3-030-62041-7
    DOI: 10.1007/978-3-030-62041-7
    DDC: 304.2
    Language: English
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    Medicinal Plants: Biodiversity, Biotechnology and Conservation (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Botany. ; Biodiversity. ; Plant biotechnology. ; Plant Science. ; Biodiversity. ; Plant Biotechnology.
    Description / Table of Contents: 1. The Current Status of Population Extinction and Biodiversity Crisis of Medicinal Plants -- 2. Medicinal Plants and Bioactive Phytochemical Diversity: A Fountainhead of Potential Drugs against Human Diseases -- 3. Threats and opportunities for sustainable use of medicinal plants in Brazilian Atlantic Forest based on the knowledge of Indigenous Peoples and Local Communities -- 4. Climate Change Impact on Medicinal Plants: An Insight from the IUCN Red List Of Threatened Species -- 5. Securing Conservation Status of Paris Polyphylla, a Medicinally Important Plant of the Indian Himalayan Region -- 6. Endophytic Fungal Diversity in Solanaceous Medicinal Plants and Their Beneficial Impact -- 7. Genetic Studies on Threatened Medicinal Plants of Brazil: Mind the Gap -- 8. Medicinal Plants of North-east India: Biodiversity and Their Ethno-Medicinal Values -- 9. Strategies for Conservation and Sustainable Use of Medicinal Plants -- 10. Scientific Databases for Conservation of Medicinal Plants -- 11. International Trade of Medicinal and Aromatic Plants (MAPs) -- 12. Inventorization of Ecology, Ethnobotany and Conservation Status of Dactylorhiza hatagirea: Problems Progress and Prospects -- 13. Conservation and Sustainable Use of Medicinal Plants -- 14. Traditional Practices of Ethnomedicinal Plants in North-East Region of India and Their Conservation for Sustainable Utilization -- 15. Occurrence and Diversity of Major Naphthoquinones in Higher Plants: Their Distribution and Conservation Strategies -- 16. Astragalus fridae genetic Source,Applications, and Conservation -- 17. Tinospora cordifolia as a Potential Candidate for Health Care Of Post-Menopausal Women -- 18. The Potential Role of Medicinal Plants, Traditional Herbal Medicines and Formulations to Overcome SARS-CoV-2 Induced Health Crisis -- 19. Bioactive Compounds from Medicinal Plants and Its Therapeutic Uses in the Traditional Health Care System -- 20. In-Vitro conservation and propagation of endangered Ethno-Medicinal Orchids from the Northeast Region of India -- 21. Artificial Seed Production and Cryopreservation Technology for Conservation of Plant Germplasm with Special Reference to Medicinal Plants -- 22. Biotechnological Studies on Nasturtium Officinale (Watercress) - An Endangered Species of Significant Relevance in Medicine, Cosmetic, and Food Industries -- 23. Isatis tinctoria L. (woad) – Cultivation, Phytochemistry, Pharmacology, Biotechnology, and Utilization -- 24. Tissue Culture Techniques to Conserve Endangered Medicinal Plants with Antimicrobial and Antiviral Activities -- 25. Insights into the In Vitro Approaches for the Production of Secondary Metabolites Towards The Conservation of Medicinal Orchids -- 26. Biotechnological Approaches for Ex Situ Conservation of Medicinal Plants -- 27. Conservation of Medicinal Plants by Tissue Culture Techniques -- 28. Current Status of Metabolic Engineering of Medicinal Plants for Production of Plant-derived Secondary Metabolites -- 29. Stationary, Agitated and Bioreactor Cultures of Verbena officinalis L. (Common Vervain) - A Potential Rich Source of Bioactive Phenolic Compounds for Pharmacy, Health Food Industry and Cosmetology.
    Abstract: This contributed volume provides a comprehensive, in-depth and subject-based reviews on the current status of active ingredients, sustainable use, biodiversity and conservation of certain endangered medicinal plants. The book also explores conventional and non-conventional biotechnological interventions for their biodiversity conservation. Medicinal plants have been used in worldwide as a major source of raw material for the traditional herbal healthcare practices as well as for drug discovery and development in pharmaceutical industry. The cumulative consequences of various human activities and environmental factors cause decline in the biodiversity of medicinal plants at an unprecedented rate worldwide. Thus, the overall understanding of ecology, species and genetic diversity along with assessment of the status of different threats and their impact on medicinal plants is crucial to sustain existing biodiversity, its utilization and conservation. All the latest advancements in the biotechnological approaches for the conservation research of endangered medicinal plants and the future perspectives have been described. This book provides comprehensive reviews spreading over about 25 chapters divided in three sections. The chapters of this book are written by recognized scientists in their respective fields which are useful to students, academicians, researchers, botanists, biotechnologists, policy makers, conservationists and industries interested in biodiversity conservation and medicinal plant research for the production of secondary metabolites.
    Type of Medium: Online Resource
    Pages: XIX, 906 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811999369
    Series Statement: Sustainable Development and Biodiversity, 33
    URL: https://doi.org/10.1007/978-981-19-9936-9
    DOI: 10.1007/978-981-19-9936-9
    DDC: 580
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    Aspects of Brazilian Floristic Diversity : From Botany to Traditional Communities (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Biodiversity. ; Plant ecology. ; Conservation biology. ; Ecology . ; Plant Science. ; Biodiversity. ; Plant Ecology. ; Conservation Biology.
    Description / Table of Contents: Flowering phenology in a restinga community: seven years of study -- Dioecy: the dimorphic sexual system and pollination in restinga vegetation -- Male and female sterility in flowering plants -- Broad-scale variation of phytoplankton richness in Brazilian inland waters -- The Importance of Palynology to Taxonomy -- Ecological Palynology -- Scientific Exploration Commission (1859-1861): Freire Allemão and the invisible network of collaborators -- The former Imperial Plant Nursery of Quinta da Boa Vista -- Medicinal plants used in Quilombola communities in Piranga, State of Minas Gerais, Brazil -- From mulungu to mamulengo”: The sharing of knowledge among teachers, academic researchers and mamulengueiros (traditional puppeteers) in a participatory workshop -- Biocultural heritage through museological narrative as a way of return on research in historical ethnobotany -- Conclusion of the reflections on Aspects of Brazilian Floristic Diversity: From Botany to Traditional Communities.
    Abstract: Aspects of Brazilian Floristic Diversity: From Botany to Traditional Communities offers a unique approach in floristic diversity of the Neotropical region, specifically encompassing the Brazilian flora. This volume combines both theoretical and applied aspects of scientific making knowledge in different perspectives of Botanical Science. In this volume, botanical specialists discuss the many different approaches of taxonomic, reproductive, ecological and ethnobotanical aspects of Brazilian floristic diversity, thereby enlightening the global interest in Neotropical species, in particular those from the Brazilian territory. The book addresses relevant questions from many points of view, including anatomy, reproduction, palinology, conservation and ethnobotany, creating an in-depth perception of the flora in its complexity constitution. The book provides a comprehensive outlook on Botany Sciences, considering the history and traditional knowledge of plants, and relating it to contemporary problems and concerns of flora conservation today. With this current perspective, this book reaches a vast audience from the research lines of Botany, and encompasses a broader and interdisciplinary understanding of Aspects of Brazilian Floristic Diversity.
    Type of Medium: Online Resource
    Pages: XXIV, 268 p. 49 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031074530
    URL: https://doi.org/10.1007/978-3-031-07453-0
    DOI: 10.1007/978-3-031-07453-0
    DDC: 580
    Language: English
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    Mechanisms and Emerging Therapies in Tremor Disorders (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Neurology . ; Neurosciences. ; Nervous system Diseases. ; Biomedical Research. ; Neurology. ; Neuroscience. ; Neurological Disorders.
    Description / Table of Contents: PART I: Fundamental Aspects -- Chapter 1. Definition of Tremor -- Chapter 2. Membrane Mechanisms of Tremor -- Chapter 3 Advances in the Genetics of Human Tremor -- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor -- PART II:Tremor in Clinical Practice -- Chapter 5. Physiologic Tremor -- Chapter 6. Rest Tremor -- Chapter 7. Postural Tremors -- Chapter 8. Isometric Tremor -- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor -- Chapter 10. Cerebellar lesions and tremor -- Chapter 11. Orthostatic Tremor -- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders -- Chapter 13 Tremor in Childhood -- Chapter 14. Metabolic Causes of Tremor -- Chapter 15. Drug-Induced Tremor -- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis -- PART III: Assessment of tremor -- Chapter 17. Signal Processing -- Chapter 18. Diffusion imaging in Tremor -- Chapter 19. The role of the noradrenergic system in tremor pathogenesis -- Chapter 20. Metabolic Networks in Parkinson’s Disease -- PART IV: Therapies -- Chapter 21. Deep brain stimulation for tremor -- Chapter 22 Mechatronic Devices for Upper Limb Tremor.
    Abstract: Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment and provides practical information for daily management. This new edition is informed by the guidelines of the Tremor Task Force of the International Parkinson and Movement Disorders Society. New chapters include Classification of Tremors, Medically Induced Tremors, Resting State fMRI, and Gabaergic Pathways. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced.
    Type of Medium: Online Resource
    Pages: X, 558 p. 86 illus., 59 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031261282
    Series Statement: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-031-26128-2
    DOI: 10.1007/978-3-031-26128-2
    DDC: 610.72
    Language: English
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    Microplastic Occurrence, Fate, Impact, and Remediation (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Analytical chemistry. ; Toxicology. ; Biomedical Research. ; Analytical Chemistry. ; Toxicology.
    Description / Table of Contents: Microplastic research publications from 1991 to 2020 -- Characterization and toxicology of microplastics in soils, water and air -- Coral feeding behavior on microplastics -- Microplastics remediation in the aqueous environment -- Removal of environmental microplastics by advanced oxidation processes -- Techniques for removal and degradation of microplastics -- Occurrence and removal of microplastics in wastewater treatment plants -- Microplastic souces, transport, exposure, analysis and removal -- Airborne microplastics in outdoor and indoor environments -- Nanoplastic sources, characterization, ecological impact, remediation and policies -- Microplastics in soil-plant systems.
    Abstract: Microplastics and nanoplastics have been recently found in most environmental media and in living organisms, thus representing a serious health concern of yet poorly known adverse consequences. This book summarizes recent findings on the sources, behavior, transformation, toxicity and remediation of microplastics, with focus on soils, water, wastewater, air, soils, plants and corals. Advanced methods for sampling, characterization, removal and degradation of microplastics.
    Type of Medium: Online Resource
    Pages: VIII, 282 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031363511
    Series Statement: Environmental Chemistry for a Sustainable World, 73
    URL: https://doi.org/10.1007/978-3-031-36351-1
    DOI: 10.1007/978-3-031-36351-1
    DDC: 610.72
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    Textbook of Forensic Science (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Forensic sciences. ; Medical jurisprudence. ; Biomedical Research. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Module 1_Introduction to Forensic Science & Crime -- Module 2_Criminalistics -- Module 3_ Forensic Biological Sciences -- Module 4_Forensic Physical Sciences -- Module 5_Forensic Chemical Sciences -- Module 6_Emerging fields in Trends in Forensics.
    Abstract: This textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tears, sweat, vaginal fluids, urine, and sweat. It also provides an overview of forensic examination of different types of evidence and also includes comprehensive detailing of forensic ballistics including firearm classification, bullet comparison and matching. Further, it explores the examinations of drugs, chemicals, explosives, and petroleum products. It focuses on the various aspects of forensic toxicology, including the study of various poisons/toxins, associated signs and symptoms, a fatal dose /fatal period of poisons. The book also emphasizes digital and cyber forensics, including classification, data recovery tools, encryption and decryption methods, image, and video forensics. It is a useful resource for graduate and post-graduate students in the field of Forensic Science.
    Type of Medium: Online Resource
    Pages: XV, 839 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819913770
    URL: https://doi.org/10.1007/978-981-99-1377-0
    DOI: 10.1007/978-981-99-1377-0
    DDC: 610.72
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    Root-Galling Disease of Vegetable Plants (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Plant physiology. ; Plant diseases. ; Plant Science. ; Plant Physiology. ; Plant Pathology.
    Description / Table of Contents: Chapter 1 -- Root-knot Nematodes (Meloidogyne spp.), Chapter 2 -- Meloidogyne species: Threat to Vegetable Produce, Chapter 3 -- hemotaxis in Root-Knot Nematodes, Chapter 4 -- Phytohormone-Mediated Feeding Site Development, Chapter 5 -- 5. Current and Future Studies on the Genes for Parasitism in Meloidogyne, Chapter 6 -- Natural Product Repertoire for Suppressing the Immune Response of Meloidogyne species, Chapter 7 -- Epigenetic Mechanisms and their Role in Root Gall Formation,Chapter 8 -- Mass Spectrometry Imaging (MSI) and Root Gall Elucidation, Chapter 9 -- 9. Root-Knot Disease Complex: An Interactive Perspective with Microorganisms, Chapter 10 -- Breeding for Resistance in Vegetables against Meloidogyne species causing Root Gall Disease, Chapter 11 -- An Overview of Predacious Fungi for the Management of Root-knot Disease in Vegetables, Chapter 12 -- Biofertilizer of Organic Origin for Management of Root Galling Disease of Vegetables, Chapter 13 -- Prospects for the Use of Metabolomics Engineering in Exploring and Harnessing Chemical Signalling in Root Galls.
    Abstract: This book provides the most comprehensive and up-to-date review of research on vegetable plants associated with root-galls disease caused by root-knot nematodes (RKNs), Meloidogyne spp. Vegetables retain a key position in cultural cuisines and their consumption worldwide due to rich sources of micronutrients, including vitamins, minerals and antioxidants, but root galls disease of these crops caused by RKNs steals both quantity and quality from production. The field of plant nematology has experienced exponential growth over the past decade, and these RKNs are now known as widely damaging obligate plant parasites of vegetable plants. Advances are being made in understanding their biology, parasitism in the root system, giant cell development, root gall formation, chemical signalling, root-knot disease complexes, and management systems. This compilation provides an invaluable resource for studying root-galls disease of vegetable plants to those readers associated with plant nematology, plant pathology, plant protection, and agricultural science, including researchers, teachers, advanced undergraduates and graduate students, and even agricultural extension agents and farmers.
    Type of Medium: Online Resource
    Pages: XIX, 338 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938926
    URL: https://doi.org/10.1007/978-981-99-3892-6
    DOI: 10.1007/978-981-99-3892-6
    DDC: 580
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    Crime Scene Management within Forensic Science : Forensic Techniques for Criminal Investigations (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Medicine Research. ; Biology Research. ; Forensic sciences. ; Toxicology. ; Biomedical Research. ; Forensic Science. ; Toxicology.
    Description / Table of Contents: 1 Forensic Dna Analysis: A Powerful Investigative Tool -- 2 “Crime Scene Management Within Forensic Science-Forensic Techniques For Criminal Investigations -- 3 Small Size, Big Impact: Insects For Cadaver Examination -- 4 Dermatoglyphics & Other Impressions: Deciphering The Potential Of A Unique Hominid Niche -- 5 Postmortem Toxicology: A facet of drugs of expedites crimes -- 6 Forensic Biology: A Passport For Biological Evidence -- 7 Sexual offences: Recent methods of Investigation -- 8 Investigation Of Disaster Victim Identification -- 9 Review On Clinical Forensic Medicine -- 10 Firearms and Ammunitions: A sentient approach in criminal investigation -- 11 Digital and Cyber Forensics: A Contemporary evolution in Forensic Sciences -- 12 Fire Investigation: Arson Or Accidental -- 13 Psychological Evaluations: An Indoor game of Criminal Minds -- 14 Competence of Evidences: A Pragmatic Approach in Court of Law -- 15 Penology: A friend or foe for criminal justice system -- 16 Chain Of Custody: Scaling The Investigation To The Event. .
    Abstract: This book, the second volume of Crime Scene Management in Forensic Sciences, reviews the role and impact of forensic evidence in criminal investigations. It also addresses the importance of post mortem examination in criminal cases. The book investigates the use of insects and arthropods to estimate post mortem intervals during forensic investigations. Further, it discusses the physiological effects of xenobiotics at the time of death, based on their concentration and distribution in the body at autopsy. Importantly, it also discusses digital forensic investigation, which can be used for the analysis of digital evidence produced at a court of law. Lastly, it defines the structure and legal framework of these forensic evidences for the effective administration of the criminal justice system. It is an excellent source of information for forensics scientists and legal professionals.
    Type of Medium: Online Resource
    Pages: VIII, 418 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811666834
    URL: https://doi.org/10.1007/978-981-16-6683-4
    DOI: 10.1007/978-981-16-6683-4
    DDC: 610.72
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    Genomic Designing for Abiotic Stress Resistant Cereal Crops (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Genomic Improvement of Rice for Drought, Aluminum, and Iron Toxicity Stress Tolerance -- Advances In Breeding For Abiotic Stress Tolerance in Wheat -- Resistance to Abiotic Stress: Theory and Applications in Maize Breeding -- Genetic Diversity for Barley Adaptation to Stressful Environments -- Advances in Genomic Designing for Abiotic Stress Tolerance in Sorghum -- Genomic Designing for Abiotic Stress Tolerance in Pearl Millet -- Genomic Designing for Abiotic Stress Tolerance in Foxtail millet -- Genomic-Assisted Breeding in Finger Millet.
    Abstract: This book presents abiotic stresses that cause crop damage in the range of 6-20%. Understanding the interaction of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., is important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in cereal crops is imperative for addressing FPNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has facilitated precise information about the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a cereal crop in this volume are deliberate on different types of abiotic stresses and their effects on and interaction with crop plants; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; are brief on the classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; elucidate on the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different emerging genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Type of Medium: Online Resource
    Pages: XXIV, 317 p. 24 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030758752
    URL: https://doi.org/10.1007/978-3-030-75875-2
    DOI: 10.1007/978-3-030-75875-2
    DDC: 580
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    Nuclear Receptors in Human Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Molecular biology. ; Metabolism. ; Genetics. ; Cytology. ; Biomedical Research. ; Molecular Biology. ; Metabolism. ; Genetics and Genomics. ; Cell Biology.
    Description / Table of Contents: Introduction (Moray J Campbell & Charlotte L Bevan) -- Overview (Jason Carroll) -- Part I: Reproduction and Development -- Chapter 1. Nuclear receptors in pregnancy and outcomes: clinical perspective (Luiza Borges Manna & Catherine Williamson) -- Chapter 2. Female Reproductive Systems: hormone dependence and receptor expression (Philippa TK Saunders) -- Chapter 3. Nuclear receptors in ovarian function (Darryl Russell & Doan Thao Dinh) -- Part II: Metabolism -- Chapter 4. Nuclear receptors in energy metabolism (Alina Walth, Stephan Herzig & Maria Rohm) -- Chapter 5. Nuclear Receptors and lipid sensing (James L Thorne and Giorgia Cioccoloni) -- Part III: Central Systems -- Chapter 6. Corticosteroid receptors in Cardiac health and disease (Jessica Ivy, Gillian Gray, Megan Holmes, Martin Denvir, Karen Chapman) -- Chapter 7. Physiological convergence and antagonism between GR and PPARγ in inflammation and metabolism (Marija Dacic, Gayathri Shibu and Inez Rogatsky) -- Chapter 8. Circadian Rhythm and Nuclear Receptors (David W Ray) -- Chapter 9. Vitamin D and gut health (James C Fleet) -- Part IV: Cancer -- Chapter 10. Estrogen Receptor alpha and ESR1 Mutations in Breast Cancer (Jaymin Patel & Rinath Jeselsohn) -- Chapter 11. AR structural variants and prostate cancer (Laura Cato) -- Chapter 12. ERβ and inflammation (Linnea Hases, Amena Archer & Cecilia Williams) -- Chapter 13. Genomic insights into non-steroidal nuclear receptors in prostate and breast cancer (Sajad A Wani & Moray Campbell) -- Part V: New developments in transcriptional control by nuclear receptors -- Chapter 14. Protein condensation in the nuclear receptor family; implications for transcriptional output (Monique Appelman, Elle Hollaar, Jurian Schuijers & Saskia WC van Mil) -- Chapter 15. Prostate cancer epigenetic plasticity and enhancer heterogeneity: molecular causes, consequences and clinical implications (Jeroen Kneppers, Andries M Bergman & Wilbert Zwart) -- Chapter 16. Epigenetic coregulation of androgen receptor signaling (Rayzel Fernandes, Damien A. Leach & Charlotte Bevan) -- Part VI: Clinical Translation -- Chapter 17. Cllnical Translation: Targeting the Estrogen Receptor (Jennifer O. Lauchle & Ciara Metcalfe) -- Chapter 18. Drugging the undruggable: targeting the N-terminal domain of nuclear hormone receptors (Marianne Sadar) -- Chapter 19. Genetic Variation and Mendelian Randomization approaches (Mojgan Yazdanpanah, Nahid Yazdanpanah & Despoina Manousaki) -- Index.
    Abstract: This book addresses and dissects the roles and crosstalk mechanisms for the 48 human nuclear receptors (NR) in human health and disease. After a State-of-the-Art introduction by an undisputed and celebrated field leader to provide an overview of the field and its significance, chapters are organized into six sections. The first three sections discuss NR roles in Reproduction & Development, Metabolism and Central Systems. These present to the reader our current understanding of NR signaling in the development and functioning of the reproductive system; the roles in the regulation of energy metabolism; and how NR signaling is more widely integrated into systemic functions from calcium flux to circadian rhythm. The subsequent three sections dissect how aberrant NR functions drive Cancer; how new insights into Genomic Interaction are helping to reveal how NR disruption drives disease; and finally, how Translational Efforts are exploiting this understanding from developing novel NR ligands to establishing how underlying genetic variation impacts NR function. Within these sections the chapters also illustrate emerging understanding of how the epigenome and non-coding genome combine to regulate NR function and impact dysfunction. Increasingly these insights cross-fertilize over cell and disease boundaries and it is unsurprising that NR are being explored in novel and new arenas such as the context of neurological disorders and depression. Thus, there is wide scope for re-purposing of licensed drugs and development of new NR-targeting therapies for a host of conditions and diseases. This unique book brings together many of the leading figures in NR research from across the globe, to discuss emerging roles and their implications for human health and disease. It summarizes the state of the art and shows signposts for future research to further shape this influential field.
    Type of Medium: Online Resource
    Pages: XII, 346 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031118364
    Series Statement: Advances in Experimental Medicine and Biology, 1390
    URL: https://doi.org/10.1007/978-3-031-11836-4
    DOI: 10.1007/978-3-031-11836-4
    DDC: 610.72
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    Mineral Biofortification in Crop Plants for Ensuring Food Security (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Human ecology Study and teaching. ; Plant Science. ; Environmental Studies.
    Description / Table of Contents: 1. Agronomic Biofortification- An Effective Tool for Alleviating Nutrient Deficiency in Plants and Human Diet -- 2. The Role of Biofortification in Enhancing Plant Growth, Development, Yield, and Quality -- 3. Improving Zinc Biofortification in Plants 4. Biofortification of Zinc: Uptake from the Soil and Transportation up to the Grains through ZIP Family Transporters -- 5. Mechanisms of Iron Uptake and Homeostasis in Plants: Implications for Biofortification in Cereal Grains -- 6. Selenium Biofortification in Agronomic Crops -- 7. Selenium Bio-fortification in Cereal Crops: An Overview -- 8. Nanoparticles Based Biofortification in Food Crops: Overview, Implications, and Prospects -- 9. Role of Nanoparticles in Improving Biofortification -- 10. Role of Nanoparticles in Improving Biofortification of Zinc and Iron in Vegetables -- 11. Scope of Seed Priming in Inducing Biofortification in Plants -- 12. Biofortification Through Seed Priming in Food Crops; Potential Benefits and Future Scope -- 13. Biochar for the Improvement of Crop Production -- 14. Phytohormones as Stress Mitigators in Plants.
    Abstract: This book provides a comprehensive summary of the recent advances in the biofortification of plants under climate change and how it affects food security globally. The need for mineral biofortification to eradicate or alleviate malnutrition through sustainable agriculture is also discussed. Biofortification of edible plants is considered the most appropriate approach to alleviate nutritional problems and nutrient deficiencies. In contrast, biofortification focuses on improving the nutritional content of the region's current agricultural biodiversity while preserving its habits and customs. Emphasis is also placed on recent advances and developments in omics, particularly metabolomics and related techniques, to unravel the potential alterations in plants caused by biofortification. The book brings together eminent scientists to present the latest developments in the field. This timely publication addresses practical scenarios of bio-fortified food production and climate change. The book focuses on the methods, techniques, and environmental changes used to enhance and improve agricultural products. This book is one of the first to provide information on the use of modern biotechnologies to modify crops for health benefits. It also examines the mechanisms of the plant responses to genetically induced biofortification, the production and responses of fortified plants under climate change, and their effects on food security. The book will be useful for students and researchers, especially crop scientists, environmental scientists, biotechnologists, botanists, and agronomists, to understand the techniques and mechanisms of biofortification, and responses of biofortified plants under climate change.
    Type of Medium: Online Resource
    Pages: XI, 338 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819940905
    URL: https://doi.org/10.1007/978-981-99-4090-5
    DOI: 10.1007/978-981-99-4090-5
    DDC: 580
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    Approaches for Science Illustration and Communication (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Anatomy. ; Information visualization. ; Biophysics. ; Biomedical Research. ; Anatomy. ; Data and Information Visualization. ; Bioanalysis and Bioimaging.
    Description / Table of Contents: Chapter 1. The Importance of Integrating the Visual Arts into the Medical Curriculum -- Chapter 2. Using Medical Illustration to Improve Understanding of Endometriosis -- Chapter 3. Editorial Medical and Scientific Illustration -- Chapter 4. Current Approaches in Narrative Medical Visualization -- Chapter 5. Animation for Science Communication: A Description of the Production Process and Contexts for Using Science Animation -- Chapter 6. Effect of the Rings: A Visual Story Design Comparing Three Chemical Characters -- Chapter 7. Diabetes Year One, Random Fluctuations and Mental Goblins: Auto-Ethnographic Pathographies and Medical Comics -- Chapter 8. Playing with Science: Games as a Medium of Science Communication -- Chapter 9. Increasing Microbiology Literacy about the Public Health Threat of Antimicrobial Resistance Through Art-Science Interactions -- Chapter 10. Collaged Creatures: Using Collage Art Practice and Posthuman Ethics to Discuss Bioengineering Hybrids.
    Abstract: This edited book explores the breadth of approaches undertaken by scientists, artists and communicators in their crucial role making science accessible, engaging and impactful. Contemporary approaches in science illustration and visualization include a variety of creative methodologies that are valuable for effective communication, teaching, learning and professional practice. These range in method from anatomical drawings used in medical curricula, to 2D animations and editorial illustrations available in the public realm. They also include unexpected approaches such as the use of tabletop board games, comics and collage in understanding our bodies, emergent health threats and cutting-edge science developments. If you are a scientist seeking to enhance your ability to communicate your research or an artist interested in biomedical visualization, this volume serves as an introduction to contemporary approaches in science illustration and communication. By understanding the creative methods and techniques employed in this field, we can collectively work towards fostering a deeper appreciation of art in science, and continue to captivate and inspire audiences worldwide. .
    Type of Medium: Online Resource
    Pages: XVI, 252 p. 158 illus., 140 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031416521
    Series Statement: Biomedical Visualization, 4
    URL: https://doi.org/10.1007/978-3-031-41652-1
    DOI: 10.1007/978-3-031-41652-1
    DDC: 610.72
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    The Alfalfa Genome (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Economic Importance, Practical Limitations to Production, Management and Breeding Targets of Alfalfa -- Chapter 2. Factors Influencing Yield and Quality -- Chapter 3. The Origin, Evolution and Genetic Diversity of Alfalfa -- Chapter 4. Germplasm Collection, Genetic Resources and Gene Pools in Alfalfa -- Chapter 5. Biotechnology Advances in Alfalfa -- Chapter 6. Sequencing, Assembly and Annotation of the Alfalfa Genome -- Chapter 7. Transcription Factors in Alfalfa (Medicago sativa L.): Genome-Wide Identification and a Web Resource Center AlfalfaTFDB -- Chapter 8. Genomics of Forage Quality in Alfalfa -- Chapter 9. Physiological, Morphological, Biochemical, and Genetic Responses of Alfalfa to Salinity -- Chapter 10. Developing SNPs and Strategies for Genomic Analysis in Alfalfa -- Chapter 11. Genomics Resources for Breeding in Alfalfa: Availability, Utility, and Adoption -- Chapter 12. Genomic Selection for Higher Yield and Quality in Alfalfa -- Chapter 13. Identification and Characterization of Disease Resistance Genes in Alfalfa and Medicago truncatula for Breeding Improved Cultivars -- Chapter 14. Genetic and Genomic Assessments for Improving Drought Resilience in Alfalfa -- Chapter 15. Self-Incompatibility, Inbreeding Depression, and Potential to Develop Inbred Lines in Alfalfa -- Chapter 16. Targeted Mutagenesis of Alfalfa.
    Abstract: This book is the first comprehensive compilation of deliberations on whole genome sequencing of the diploid and tetraploid alfalfa genomes including sequence assembly, gene annotation, and comparative genomics with the model legume genome, functional genomics, and genomics of important agronomic characters. Other chapters describe the genetic diversity and germplasm collections of alfalfa, as well as development of genetic markers and genome-wide association and genomic selection for economical important traits, genome editing, genomics, and breeding targets to address current and future needs. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, breeding, pathology, physiology, molecular genetics and breeding, biotechnology, and structural and functional genomics. The work is also useful to seed and forage industries.
    Type of Medium: Online Resource
    Pages: XXV, 283 p. 64 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030744663
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-74466-3
    DOI: 10.1007/978-3-030-74466-3
    DDC: 580
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    Polymeric Biomaterials for Tissue Regeneration : From Surface/Interface Design to 3D Constructs (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Regenerative medicine. ; Biomaterials. ; Biomedical Research. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials.
    Description / Table of Contents: Chapter 1. An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells -- Part I. Structural Scaffolds and Bio-activation -- Chapter 2. Polymeric and Biomimetic ECM Scaffolds for Tissue Engineering Applications -- Chapter 3. Versatile Hydrogels in Regenerative Medicine -- Chapter 4. Multilayer Microcapsules with Tailored Structures and Properties as Delivery Carriers for Drugs and Growth Factors -- Part II Biomaterials Surfaces/Interfaces and Bio-interactions. Chapter 5. Interactions of Biomaterial Surfaces with Proteins and Cells -- Chapter 6. Surface Modification of Tissue Engineering Scaffolds -- Chapter 7. Gradient Biomaterials and Their Impact on Cell Migration -- Chapter 8. Stem Cell Differentiation Mediated by Biomaterials/Surfaces -- Part III Regeneration of Some Clinic-Targeted Tissues -- Chapter 9. Cartilage Regeneration -- Chapter 10. Skin Regeneration -- Chapter 11. Regeneration of Blood Vessels -- Chapter 12. Cardiac repair and regeneration -- Chapter 13. Nerve Regeneration.
    Abstract: This book reviews state of the art of polymeric biomaterials for regenerative medicine and highlights advances in both fundamental science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physiochemical property modulation, as well as their influence on the adhesion and performance of biomolecules, cells, and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies. In the second edition, most of the chapters are updated according to the latest progress of this research field. A new chapter on nerve regeneration is also included.
    Type of Medium: Online Resource
    Pages: VIII, 577 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789819969487
    URL: https://doi.org/10.1007/978-981-99-6948-7
    DOI: 10.1007/978-981-99-6948-7
    DDC: 610.72
    Language: English
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    Spores : Tulips with Fever, Rusty Coffee, Rotten Apples, Sad Oranges, Crazy Basil. Plant Diseases that Changed the World as Well as My Life (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Food Safety measures. ; Plant diseases. ; Agriculture. ; Environment. ; Public health. ; Plant Science. ; Food Safety. ; Plant Pathology. ; Agriculture. ; Environmental Sciences. ; Public Health.
    Description / Table of Contents: Introduction -- Ancient Spores -- Spores of My Life -- Scary Spores -- Spores of the Future -- Conclusions.
    Abstract: This book aims to describe, though in a quite light way, the social role of plant diseases, letting the reader know the topical importance of plant pathology, as well as the role of plant pathologists in our society. Plant diseases caused, in the past, significant economic losses, deaths, famine, wars, and migration. Some of them marked the history of entire countries. One example among many: the potato late blight in Ireland in 1845. Today plant diseases are still the cause of deaths, often silent, in developing countries, and relevant economic losses in the industrialized ones. This book, written with much passion, neither wants to be a plant pathology text. On the contrary, it wants to describe, in simple words, often enriched by the author's personal experience, various plant diseases that, in different times and countries, did cause severe losses and damages. Besides the so-called “historical plant diseases”, in the process of writing this book, she wanted to describe also some diseases that, though not causing famine or billions of losses, because of their peculiarity, might be of interest for the readers. Thus, this book has not been conceived and written for experts, but for a broader audience, of different ages, willing to learn more about plant health and to understand the reasons why so many people in the past and nowadays choose to be plant pathologists. This is because plants produce most of the food that we consume, that we expect healthy and safe, and because plants make the world beautiful. The title “Spores” is evocative of the reproduction mean of fungi. Spores are small, light structures, often moving fast. The chapters of this book are short and concise. Just like spores!
    Type of Medium: Online Resource
    Pages: XXVI, 289 p. 174 illus., 166 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030699956
    URL: https://doi.org/10.1007/978-3-030-69995-6
    DOI: 10.1007/978-3-030-69995-6
    DDC: 580
    Language: English
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    Heat Shock Proteins in Human Diseases (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Proteins . ; Cytology. ; Biomedical Research. ; Protein Biochemistry. ; Cell Biology.
    Description / Table of Contents: Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and Cancer Immunotherapy -- Chaperonin Hsp60 and Cancer Therapies -- Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment -- Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics -- Multifaceted Roles of Heat Shock Factor 1 (HSF1) in Cancer -- Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer -- Heat Shock Proteins in Atrial Fibrillation -- Threading Microarrays into Novel Applications -- Regulation of Kaposi’s Sarcoma-associated Herpesvirus Biology by Host Molecular Chaperones -- Role of Heat Shock Factors in Diseases and Immunity -- Heat Shock Proteins and Pain -- Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway -- Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with diverse Cellular and Molecular Functions -- Roles of Heat Shock Proteins on Antigen Presentation -- Heat shock proteins mediate anastasis and plasticity of thermotolerant cells.
    Abstract: The book Heat Shock Proteins in Human Diseases provides the most comprehensive review on contemporary knowledge on the role of heat shock proteins (HSP) in various types of human diseases including cancer, cardiovascular disease, microbiology and inflammation. These diseases were specifically chosen due to their dismal prognosis, the survival benefit offered by the current standards do not greatly impact the overall survival statistics with the disease and are associated with toxicity. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in human diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 297 p. 31 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030622893
    Series Statement: Heat Shock Proteins, 21
    URL: https://doi.org/10.1007/978-3-030-62289-3
    DOI: 10.1007/978-3-030-62289-3
    DDC: 610.72
    Language: English
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    New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Drug delivery systems. ; Regenerative medicine. ; Biomedical Research. ; Pharmacology. ; Drug Delivery. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Approaches Towards Synthetic Signal Transduction in Phospholipid Bilayers -- Development of Novel Versatile Theranostic Platforms Based on Titanate Nanotubes: Towards Safe Nanocarriers for Biomedical Applications -- Metal-organic Framework—Polymer Mixed-Matrix Membranes -- Insights into Adaptive Selforganized Supramolecular Structures from Molecular Modeling and Visualization -- Self-Assembled Metallacages as Drug Delivery Systems: Design Concepts and Challenge -- Functional Microporous Polymer Networks: Synthesis and Applications -- A Story on Carbon Dioxide and its Hydration -- Inverse Design and Hierarchical Multiscale Modelling of Biological Matter -- DNA-Directed Self-assembly of Macromolecular Structures -- Luminescent Complexes and their Assemblies : from Understanding to Artificial Virus -- Tailor-Made Polymers and Nanoparticles for Applications in Nanomedicine -- Squalene-based Nanomedicines : An Original and Efficient Approach for the Treatment of Neurological Disorders without Crossing the Blood-Brain Barrier -- Biodegradable Nanoparticles for Specific Drug Transport -- Multivalent rotaxanes designed as antibiofilm agents -- Measuring Ionic Transport through Lipid Bilayers -- Polymeric Carriers for Transporting Nucleic Acids - Contributions to the Field -- Smart Polymeric Materials for Drug Delivery -- Supramolecular Guanosine-quadruplex Hydrogels and Hydrogel Composites for Cell Growth Applications -- Hydrogelation of Chitosan with Monoaldehydes towards Biomaterials with Tuned Properties -- Inorganic Nanoarticles as Free Radical Scavengers -- A Microbiological Epilogue - Nosocomial Infections -- Molecular Dynamic Simulations and In Silico Analysis of Supramolecular Self-Assembled Structures -- Validation of the Non Toxicity of Non Viral Genetic -- Kinetics Transport of Ions/Water Through Nano-Scale Channels : Review And Update.
    Abstract: This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations. The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.
    Type of Medium: Online Resource
    Pages: XII, 371 p. 174 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030574567
    URL: https://doi.org/10.1007/978-3-030-57456-7
    DOI: 10.1007/978-3-030-57456-7
    DDC: 610.72
    Language: English
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    Mineral nutrition of tropical plants (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Plant physiology. ; Agriculture. ; Forestry. ; Plant Science. ; Plant Physiology. ; Agriculture. ; Forestry.
    Description / Table of Contents: Introduction to Plant Nutrition -- Ion Uptake by Roots -- Foliar Ion Uptake -- Nitrogen -- Sulphur -- Phosphorus -- Potassium -- Calcium -- Magnesium -- Boron -- Zinc -- Manganese -- Iron -- Copper -- Molybdenum -- Chlorine -- Nickel -- Potentially toxic metals -- Visual and Leaf Diagnosis -- Interactions between nutrients.
    Abstract: This textbook aims to describe the role of minerals in plant life cycle; how these nutrients are absorbed, distributed, stored; what functions each mineral plays and the disorders that their excess or absence may cause. From an agronomic perspective, such knowledge is key to boost crop production and improve its quality, and it also helps understand how to better manage fertilizers and prevent environmental issues. The book has focus on tropical agriculture and its specific demands, providing examples of major crops (such as sugarcane, soybeans, coffee etc), silviculture and pasture species.
    Type of Medium: Online Resource
    Pages: XVII, 339 p. 119 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030712624
    URL: https://doi.org/10.1007/978-3-030-71262-4
    DOI: 10.1007/978-3-030-71262-4
    DDC: 580
    Language: English
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    Genomic Designing for Abiotic Stress Resistant Vegetable Crops (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Tomato -- Potato -- Capsicums -- Eggplant -- Vegetable Brassica -- Cucurbits -- Allums -- Amaranth.
    Abstract: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in vegetable crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a vegetable crop or crop group in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops.
    Type of Medium: Online Resource
    Pages: XXIII, 324 p. 16 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031039645
    URL: https://doi.org/10.1007/978-3-031-03964-5
    DOI: 10.1007/978-3-031-03964-5
    DDC: 580
    Language: English
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    Translating Physiological Tools to Augment Crop Breeding (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Botany. ; Plant physiology. ; Agricultural genome mapping. ; Agriculture. ; Plant Science. ; Plant Physiology. ; Agricultural Genetics. ; Agriculture.
    Description / Table of Contents: 1. Importance of integrating physiological breeding to augment crop breeding -- 2. Stacking of complex traits through physiological pre breeding -- 3. Strategies to develop heat and drought tolerant wheat varieties following physiological breeding -- 4. Developing crop varieties by physiological breeding for improving plant nutrition -- 5. Role of Transpiration in Regulating Leaf Temperature and its Application in Physiological Breeding -- 6. Photosynthesis as a trait for improving yield potential in crops -- 7. Cuticular waxes and its application in crop improvement -- 8. Radiation use efficiency (RUE)-target for improving yield potential: Current status and future prospect -- 9. Application of Stable Isotopes in Crop Improvement -- 10. Root phenotyping for improved resource use efficiency in crops -- 11. Root system architecture and phenotyping for improved resource use efficiency in crops -- 12. Harnessing Root associated traits and Rhizosphere efficiency for Crop improvement -- 13. High throughput phenomics of crops for water and nitrogen stress -- 14. Metabolomics as a selection tool for abiotic stress tolerance in crops -- 15. Remote Sensing Algorithms and their Applications in Plant Phenotyping -- 16. Endophyte mediated crop improvement: Manipulation of abiotic stress‐specific traits -- 17. Impact of high temperature stress on selected food grain crops -- 18. Morpho-physiological basis of finger millet to withstand climatic extremes: A special reference to drought -- 19. Comprehending the physiological efficiency of millets under abiotic stress -- 20. Role of Next-generation sequencing in trait identification, genetic mapping, and crop improvement -- 21. Application of Artificial Intelligence and Machine Learning in Agriculture.
    Abstract: This book covers different physiological processes, tools, and their application in crop breeding. Each chapter emphasizes on a specific trait/physiological process and its importance in crop, their phenotyping information and how best it can be employed for crop improvement by projecting on success stories in different crops. It covers wide range of physiological topics including advances in field phenotyping, role of endophytic fungi, metabolomics, application of stable isotopes, high throughput phenomics, transpiration efficiency, root phenotyping and root exudates for improved resource use efficiency, cuticular wax and its application, advances in photosynthetic studies, leaf spectral reflectance and physiological breeding in hardy crops like millets. This book also covers the futuristic research areas like artificial intelligence and machine learning. This contributed volume compiles all application parts of physiological tools along with their advanced research in these areas, which is very much need of the hour for both academics and researchers for ready reference. This book will be of interest to teachers, researchers, climate change scientists, capacity builders, and policy makers. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, physiology, botany, ecology, and environmental sciences. National and international agricultural scientists will also find this a useful resource.
    Type of Medium: Online Resource
    Pages: XIV, 457 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811974984
    URL: https://doi.org/10.1007/978-981-19-7498-4
    DOI: 10.1007/978-981-19-7498-4
    DDC: 580
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    Trends in Biomedical Research (2020)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Medical care. ; Human physiology. ; Biomedical Research. ; Health Care. ; Human Physiology.
    Description / Table of Contents: Targeted Drug Delivery from Titanium Implants: A Review of Challenges and Approaches -- Reliability of Magnetic Resonance Tractography in Predicting Early Clinical Improvements in Patients with Diffuse Axonal Injury -- Integrated Thermal Rehabilitation: a New Therapeutic Approach for Disabilities -- The Cat Pet as a Source Intensification of Atopic Dermatitis -- Clinical Course and Outcome of Community Acquired Bacterial Meningitis in Cancer Patients -- Influence of Coping Strategy on Perception of Anxiety and Depression in Patients with Non-Small Cell Lung Cancer -- Inflammatory Markers during Continuous High Cut-Off Hemodialysis in Patients with Septic Shock and Acute Kidney Injury -- Body Composition and Biochemical Markers of Nutrition in Non-Dialysis Dependent Chronic Kidney Disease -- Biocompatibility of hemodialysis -- Decreasing Vaccination Coverage Rates against Hepatitis B and Tuberculosis in Newborns -- Virological and Epidemiological Situation in the Influenza Epidemic Seasons 2016/17 and 2017/18 in Poland -- Epidemic Influenza Seasons from 2008 to 2018 in Poland: A Focused Review of Virological Characteristics.
    Abstract: This book addresses hot issues in the research and management of difficult-to-treat medical disorders that are commonly encountered, but for which the underlying mechanisms are often unknown. These include the adverse effects of hemodialysis and its biocompatibility in chronic kidney insufficiency, particularly related to malnutrition and inflammation, or the vulnerability of cancer patients to bacterial meningitis, the infection that remains underdiagnosed due to limited expression of symptoms. The book also covers other key topics, such as the psychological care of lung cancer patients; difficulties in the diagnosis of diffuse axonal injury in traumatic brain injury – a disorder with a poor prognosis and high mortality rate; and the virological aspects of seasonal influenza epidemic outbreaks – a perennial modern scourge. Further, it addresses recent developments in targeted drug delivery from titanium implants and a novel integrated thermal approach to rehabilitation of neurodegeneration-related disabilities. Featuring the latest interdisciplinary trends in biomedicine, this book connects research, theory and practice to help alleviate suffering caused by a variety of diseases. It is a resource for medical professionals, including academics, practitioners and all allied healthcare workers.
    Type of Medium: Online Resource
    Pages: VI, 121 p. 25 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030412197
    Series Statement: Clinical and Experimental Biomedicine, 1251
    URL: https://doi.org/10.1007/978-3-030-41219-7
    DOI: 10.1007/978-3-030-41219-7
    DDC: 610.72
    Language: English
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    Deep Learning for Biomedical Data Analysis : Techniques, Approaches, and Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Artificial intelligence. ; Bioinformatics. ; Biomedical Research. ; Artificial Intelligence. ; Bioinformatics.
    Description / Table of Contents: 1-Dimensional Convolution Neural Network Classification Technique for Gene Expression Data -- Classification of Sequences with Deep Artificial Neural Networks: Representation and Architectural Issues -- A Deep Learning Model for MicroRNA-Target Binding -- Recurrent Neural Networks Architectures for Accidental Fall Detection on Wearable Embedded Devices -- Medical Image Retrieval System using Deep Learning Techniques -- Medical Image Fusion using Deep Learning -- Deep Learning for Histopathological Image Analysis -- Innovative Deep Learning Approach for Biomedical Data Instantiation and Visualization -- Convolutional Neural Networks in Advanced Biomedical Imaging Applications -- Deep Learning for Lung Disease Detection from Chest X-Rays Images -- Deep Learning in Multi-Omics Data Integration in Cancer Diagnostic -- Using Deep Learning with Canadian Primary Care Data for Disease Diagnosis -- Brain Tumor Segmentation and Surveillance with Deep Artificial Neural Networks.
    Abstract: This book is the first overview on Deep Learning (DL) for biomedical data analysis. It surveys the most recent techniques and approaches in this field, with both a broad coverage and enough depth to be of practical use to working professionals. This book offers enough fundamental and technical information on these techniques, approaches and the related problems without overcrowding the reader's head. It presents the results of the latest investigations in the field of DL for biomedical data analysis. The techniques and approaches presented in this book deal with the most important and/or the newest topics encountered in this field. They combine fundamental theory of Artificial Intelligence (AI), Machine Learning (ML) and DL with practical applications in Biology and Medicine. Certainly, the list of topics covered in this book is not exhaustive but these topics will shed light on the implications of the presented techniques and approaches on other topics in biomedical data analysis. The book finds a balance between theoretical and practical coverage of a wide range of issues in the field of biomedical data analysis, thanks to DL. The few published books on DL for biomedical data analysis either focus on specific topics or lack technical depth. The chapters presented in this book were selected for quality and relevance. The book also presents experiments that provide qualitative and quantitative overviews in the field of biomedical data analysis. The reader will require some familiarity with AI, ML and DL and will learn about techniques and approaches that deal with the most important and/or the newest topics encountered in the field of DL for biomedical data analysis. He/she will discover both the fundamentals behind DL techniques and approaches, and their applications on biomedical data. This book can also serve as a reference book for graduate courses in Bioinformatics, AI, ML and DL. The book aims not only at professional researchers and practitioners but also graduate students, senior undergraduate students and young researchers. This book will certainly show the way to new techniques and approaches to make new discoveries.
    Type of Medium: Online Resource
    Pages: VI, 359 p. 130 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030716769
    URL: https://doi.org/10.1007/978-3-030-71676-9
    DOI: 10.1007/978-3-030-71676-9
    DDC: 610.72
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    Medical Visualization and Applications of Technology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Anatomy. ; Medical education. ; Virtual reality. ; Augmented reality. ; Biomedical Research. ; Anatomy. ; Medical Education. ; Virtual and Augmented Reality.
    Description / Table of Contents: Part I. Healthcare -- Chapter 1. Is It Time to FONA Friend? A Novel Mixed Reality Front of Neck Access Simulator -- Chapter 2. “Learning About Skin Breakdown” – Design, Development and Evaluation of an Augmented Reality Application to Inform about Pressure Ulcers (sores) and Moisture Lesions -- Chapter 3. The Use of 3D-Printing and Injection Moulding in the Development of a Low-Cost, Perfused Renal Malignancy Model for Training of Robot-Assisted Laparoscopic Partial Nephrectomy -- Chapter 4. The Co-IMMUNicate App: An Engaging and Entertaining Education Resource on Immunity to Respiratory Viruses -- Part II. Education -- Chapter 5. Application of AR and 3D Technology for Learning Neuroanatomy -- Chapter 6. Communicative Powers of Interactive Digital Mediums in the Field of Polyomics -- Chapter 7. SkilletonVR: Canine Skeleton VR -- Chapter 8. Using Holograms to Engage Young People with Anatomy -- Chapter 9. The Digital Dolphin: Are 3D Mobile Based and Interactive Models a Useful Aid to Volunteers on Stranding Schemes Learning the Basic Anatomy and Pathology of Cetaceans? -- Chapter 10. The Impact of the COVID Crisis on Anatomical Education: A Systematic Review.
    Abstract: This edited book explores the use of technology to enable us to visualize the life sciences in a more meaningful and engaging way. It will enable those interested in visualization techniques to gain a better understanding of the applications that can be used in visualization, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualization techniques and technologies for the historical and forensic settings. The reader will be able to explore the utilization of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences. We have something for a diverse and inclusive audience ranging from healthcare, patient education, animal health and disease and pedagogies around the use of technologies in these related fields. The first four chapters cover healthcare and detail how technology can be used to illustrate emergency surgical access to the airway, pressure sores, robotic surgery in partial nephrectomy, and respiratory viruses. The last six chapters in the education section cover augmented reality and learning neuroanatomy, historical artefacts, virtual reality in canine anatomy, holograms to educate children in cardiothoracic anatomy, 3D models of cetaceans, and the impact of the pandemic on digital anatomical educational resources.
    Type of Medium: Online Resource
    Pages: IX, 323 p. 270 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031067358
    Series Statement: Biomedical Visualization, 1
    URL: https://doi.org/10.1007/978-3-031-06735-8
    DOI: 10.1007/978-3-031-06735-8
    DDC: 610.72
    Language: English
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    Career Options in the Pharmaceutical and Biomedical Industry : An Insider’s Guide (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Vocational guidance. ; Career education. ; School management and organization. ; School administration. ; Biomedical Research. ; Career Counseling. ; Career Skills. ; Organization and Leadership.
    Description / Table of Contents: Part 1: Setting the scene -- Chapter 1: Life after Academia: Launching your Pharma/Biotech Career -- Chapter 2: Competences for Pharmacists -- Chapter 3: Job and Career Opportunities in the Pharmaceutical Industry: An Overview -- Part 2: Opportunities along the drug/product life cycle -- Chapter 4: Career Opportunities in Toxicology -- Chapter 5: Job Possibilities in Clinical Research -- Chapter 6: How to Get and Develop a Career in a Market Access Role in the Medical Devices Industry -- Chapter 7: Job Opportunities in Pharmaceutical Marketing -- Chapter 8: Working in Medical Affairs and Clinical Operations: Life-Changing Careers -- Chapter 9: The Role of Medical Science Liaison -- Chapter 10: Career Development for Physicians in the Biopharmaceutical Industry -- Part 3: Opportunities in Supportive Functions -- Chapter 11: Job and Career Opportunities in Regulatory Affairs/Science -- Chapter 12: Job Opportunities in Clinical Research Quality Assurance -- Chapter 13: Job Opportunities in Quality Assurance Related to Manufacturing of Medicinal Products -- Part 4: Other Opportunities in the Pharmaceutical and Biomedical Sector -- Chapter 14: Careers Perspective in a Science and Technology Park -- Chapter 15: To be or not to be: Entrepreneurship and Enterprise Creation as a Way to Innovate in Life Sciences -- Chapter 16: How to Become a Successful Hospital and Community Pharmacist -- Part 5: Practical tips and tricks -- Chapter 17: A Successful Career in the Life Sciences Industry: How to Write your Strongest Resumé and Ace that Interview -- Chapter 18: Skill Building for Career Advancement: Public Speaking and Networking -- Chapter 19: Training Opportunities for a Career in the Pharmaceutical and Biomedical Industry/Sector.
    Abstract: Written by dedicated and active professionals from different areas of the pharmaceutical, biomedical, and medtech sectors, this book provides information on job and career opportunities in various life sciences industries. It also contains useful tips to launch your own startup. The pharmaceutical, biomedical and medical technology sectors offer a wide range of employment opportunities to talented and motivated young graduates. However, many of these employment prospects are not well known to early career scientists, who concentrate primarily on the scientific and academic content of their fields of interest. The book is divided into five parts: Part 1 provides an academic perspective that focuses on the specific preparation required in the final years of study to embark on a successful career in the pharmaceutical and biomedical industries. In Part 2, industry experts discuss employment possibilities all along the drug or product life cycle, from discovery research and development to commercialisation. Part 3 follows, highlighting opportunities in support functions such as regulatory affairs or quality assurance. Part 4 focuses on additional opportunities in the wider biomedical sector, while Part 5 contains practical tips and training opportunities for entering the pharmaceutical and biomedical industries. In the epilogue, the authors reflect on this fascinating field and its career prospects. The book offers a multidisciplinary perspective on career opportunities in the pharmaceutical and biomedical industry to a wide range of students and young life scientists. .
    Type of Medium: Online Resource
    Pages: XXI, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031149115
    URL: https://doi.org/10.1007/978-3-031-14911-5
    DOI: 10.1007/978-3-031-14911-5
    DDC: 610.72
    Language: English
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    Tuberculosis : Integrated Studies for a Complex Disease (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Clinical medicine Research. ; Epidemiology. ; Diseases Causes and theories of causation. ; Biomedical Research. ; Clinical Research. ; Epidemiology. ; Pathogenesis.
    Description / Table of Contents: 1. Introduction on Tuberculosis: Integrated Studies for a Complex Disease -- 2. Global Tuberculosis Epidemiology -- 3. Heterogeneity in Tuberculosis -- 4. The Unequivocal Relationship between Tuberculosis and Tobacco: Integration of Two Maladies -- 5. Relationship between Pre-existing Cancer and Tuberculosis -- 6. Laboratory Diagnosis of Tuberculosis -- 7. The Role of Diagnostic Microdevices in the Fight Against Tuberculosis -- 8. Immunodiagnostics of Tuberculosis: Recent Discoveries -- 9. Role of Bronchoscopy in Diagnostics and Treatment of Tuberculosis -- 10. Diagnosis of Childhood Tuberculosis in Low- and Middle-income Countries -- 11. Pediatric Tuberculosis: Current Evidence for Laboratory Diagnosis -- 12. A Multidisciplinary Approach Towards Finding and Treating All Tuberculosis Patients -- 13. Chemotherapy for Drug-Susceptible Tuberculosis -- 14. The Pharmacokinetic and Pharmacodynamic Properties of Antitubercular Medications -- 15. Immune Approaches In Tuberculosis Treatment -- 16. Inhalation Therapy in Pulmonary Tuberculosis -- 17. Role of Micronutrients in Tuberculosis Management -- 18. Drug Resistance in Tuberculosis: Mechanisms, Diagnosis, New Responses, and the Need for An Integrated Approach -- 19. Resistance in Tuberculosis: Molecular Mechanisms and Modulation -- 20. Personalized Tuberculosis Care for Drug-Resistant Tuberculosis -- 21. Important Targets and Inhibitors of Mycobacterium Tuberculosis -- 22. P-type ATPases: A Relevant Component in Mycobacterium tuberculosis Viability -- 23. The Challenges of Antitubercular Drug Discovery -- 24. Exploring Decaprenylphosphoryl-β-D-ribose 2’-Epimerase 1 (DprE1): A Target for Anti-Tubercular Drugs -- 25. Energy Pathways in Mycobacterium Tuberculosis -- 26. Drug Discovery for Non-Tuberculous Mycobacteria: Recent Updates -- 27. Challenges for Contact Tracing and Tuberculosis Preventive Therapy Scale-up -- 28. Exploring Problematizations Underlying Tuberculosis Control Strategies: A Cross-Country Analysis of India and Kenya -- 29. Challenges in Prevention and Management of Tuberculosis -- 30. Tuberculosis in Contacts and Healthcare Workers -- 31. Tuberculosis Among People Who Use Drugs: Multilevel Considerations for Prevention, Diagnosis, and Treatment -- 32. Anti-Tumor Necrosis Factor-α Antagonists and Tuberculosis -- 33. Breast Tuberculosis -- 34. Central Nervous System Tuberculosis: Pathogenesis, Diagnosis, and Management -- 35. Pleural Tuberculosis -- 36. Ocular Tuberculosis -- 37. Ocular Tuberculosis: Biomarkers for Risk Stratification -- 38. Bone and Joint Tuberculosis -- 39. Abdominal Tuberculosis: Pathogenesis, Clinical Features, and Diagnosis -- 40. Bovine Tuberculosis at The Interface of Cattle, Wildlife, and Humans -- 41. Evolution and Molecular Characteristics of Mycobacterium Tuberculosis and Mycobacterium Bovis -- 42. Animal Tuberculosis: Gross Lesions and Anatomopathological Diagnosis -- 43. Estimation of Microbial Mutation Rates in Tuberculosis Research -- 44. The Role of Epigenetics in the Development of Anti-Tuberculosis Drug Resistance -- 45. Multiomics Integration of Tuberculosis Pathogenesis -- 46. Lung Microbiome in Tuberculosis -- 47. The Correlation of Microbiota and Host Epigenome in Tuberculosis -- 48. The Pathogenesis and Progression of Sarcoidosis from The Standpoint of Tuberculosis -- 49. Tuberculosis: A Historical and Global Bioethical Perspective -- 50. The Problem of Tuberculosis: Myths, Stigma, and Mimics -- 51. Tuberculosis: Integrated Studies for a Complex Disease 2050.
    Abstract: Tuberculosis have been documented since antiquity and the search of the microbes that cause this disease started more than three hundred years ago. Nevertheless, tuberculosis remains an important global health issue, with millions of people affected per year in addition to millions that remain undiagnosed and untreated. Patients with tuberculosis face the full range of recurrence, reinfection, and resistance due to diagnostic, prophylactic, and therapeutic procedures that are not as effective as they should be. In addition, variability in susceptibility to tuberculosis pose a complex problem with numerous interrelated variables. This volume is devoted to the understanding of Tuberculosis focusing on its heterogeneity, its transmission, manifestations, related conditions, diagnosis, treatments, drug resistance and prevention.
    Type of Medium: Online Resource
    Pages: XXIV, 1116 p. 363 illus., 239 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031159558
    Series Statement: Integrated Science, 11
    URL: https://doi.org/10.1007/978-3-031-15955-8
    DOI: 10.1007/978-3-031-15955-8
    DDC: 610.72
    Language: English
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  • 97
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    Dietary Phytochemicals : A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Food science. ; Cancer Prevention. ; Nutrition   . ; Plant Science. ; Food Science. ; Cancer Prevention. ; Nutrition.
    Description / Table of Contents: 1. Etiology of obesity, cancer, and diabetes -- 2. Pathophysiology of Obesity and Diabetes -- 3. Pathophysiology of obesity and cancer: Drugs and signaling targets -- 4. Peptides Involved in body weight regulation -- 5. Insulin resistance- a link between obesity and cancer -- 6. Role of the cytoskeletal protein, actin in various diseases -- 7. Diabetes mellitus and its management with plant-based therapy -- 8. Fruits and vegetables as sources of functional phytochemicals for the management of obesity, diabetes, and cancer -- 9. Spices in diabetes, cancer and obesity treatment -- 10. MicroRNAs as Targets of Dietary Phytochemicals in Obesity and Cancer -- 11. Natural phenolic compounds as anti-obesityand anti-cardiovascular disease agent -- 12. Harnessing the Potential of Phytochemicals for Breast Cancer Treatment.
    Abstract: This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as anti-diabetic, anti-cancer and anti-obesity agents and describe their mechanisms to regulate cell metabolism. Written by global team of experts, Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes describes the potentials of novel phytochemicals, their sources, and underlying mechanism of action. The chapters were drawn systematically and incorporated sequentially to facilitate proper understanding. This book is intended for nutritionists, physicians, medicinal chemists, drug developers in research and development, postgraduate students and scientists in area of nutrition and life sciences.
    Type of Medium: Online Resource
    Pages: VIII, 265 p. 22 illus., 18 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030729998
    URL: https://doi.org/10.1007/978-3-030-72999-8
    DOI: 10.1007/978-3-030-72999-8
    DDC: 580
    Language: English
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  • 98
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    Online Resource
    Genomic Designing for Abiotic Stress Resistant Fruit Crops (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Genomics of Abiotic Stress Resistance in Malus domestica -- Genomic Designing for Abiotic Stress Resistant Banana -- Genetic Improvement of Citrus Limon (L. Burm f.) for Resistance to Mal Secco Disease -- Genomic Designing for Abiotic Stress Resistant Grapevine -- Wild and Related Species as a Breeding Source for Abiotic Stress Resistance of Peach Cultivars and Rootstocks -- Genomic Designing of new Almond-Peach Rootstock-variety Combinations Resistance to Plum pox virus -- Genomic Designing of New Plum Pox Virus Resistant Plumcot -- Integrated Genomic Designing and Insights for Disease Resistance and Crop Protection against Pathogens in Cherry -- Development of Abiotic Stress Tolerant Berries.
    Abstract: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in fruit crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing in many of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The seven chapters each dedicated to a fruit crop and a fruit crop group in this volume elucidate different types of abiotic stresses and their effects on and interaction with the crops; enumerate the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Type of Medium: Online Resource
    Pages: XXII, 249 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031098758
    URL: https://doi.org/10.1007/978-3-031-09875-8
    DOI: 10.1007/978-3-031-09875-8
    DDC: 580
    Language: English
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  • 99
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    Microbial Engineering for Therapeutics (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Industrial microbiology. ; Bioinformatics. ; Synthetic Biology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Industrial Microbiology. ; Computational and Systems Biology. ; Synthetic Biology.
    Description / Table of Contents: Part 1 Introduction to Microbial Engineering -- 1 Exploring the Potential of Microbial Engineering: The Prospect, Promise and Essence -- Part 2 Microbial Engineering Approaches -- 2 Role of System Biology in Microbial System -- 3 Synthetic Biology: Refining Human Health -- 4 Probiotic Engineering: A focus on Inflammatory Bowel Disease -- 5 Engineering microbes for smart diagnostics & Lab on Chip -- 6 Bacteriophage and Virus Engineering -- 7 CRISPR Technologies: A tool for Engineering Microbes -- Part 3 Health Benefits -- 8 Recombinant Vaccines: The Revolution Ahead -- 9 Microbe-Host Metabolic Interaction- Probiotic Approach -- 10 Designer Microbes: Oncotherapy approach -- 11 The human gut microbiome in health, disease and therapeutics -- 12 Use of Engineered Bacteria for Production of Green Chemicals & Pharmaceuticals -- 13 Fat Fighting Microbes. Part 4 Innovation & Translation -- 14 Scale-up of engineering strain for industrial applications -- 15 Affordable therapeutics through Engineered Microbes -- 16 COVID-19: Lesson Learnt from Diagnostics to therapeutics. .
    Abstract: This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.
    Type of Medium: Online Resource
    Pages: XI, 374 p. 45 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811939792
    URL: https://doi.org/10.1007/978-981-19-3979-2
    DOI: 10.1007/978-981-19-3979-2
    DDC: 610.72
    Language: English
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  • 100
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    Online Resource
    Phytoremediation : In-situ Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Agriculture. ; Pollution. ; Botanical chemistry. ; Plant Science. ; Agriculture. ; Pollution. ; Plant Biochemistry.
    Description / Table of Contents: In-Situ Phytoremediation of Metals -- Phytoremediation of Organic Pollutants -- Phytoremediation of Agricultural Pollutants -- Prinicples of Phytoremediation -- Rhizobacteria enhance root exudation, metal uptake and plant growth under abiotic stress -- Exploiting the Rhizosphere for Phytoremediation Enhancement -- Phytoremiediation of metals by aquatic macrophytes -- Phytoremediation using crop plants -- Phytoremediation using algae -- Impact of munitions compounds on native vegetation -- Phytoremediation of soils contaminated by hydrocarbon -- Exploitation of Rhizosphere for Phytoenhancement of HM Contaminated Industrial Soils using MYCORRHIZOREMEDIATION Technology -- Phytoremediation using Native Plants -- Phytoremediation using Aquatic Plants -- Growing Role of Biotechnology in Phytoremediation -- History of Phytoremediation -- Exploiting the Rhizosphere for Phytoremediation Enhancement -- Phytoremediation of wastewater -- Rhizosphere for Phytoremediation Enhancement.
    Abstract: This book provides in-situ phytoremediation strategies that are particularly well suited for developing nations. Its goal is to promote the use of field-tested phytoremediation methods for removing soil and water pollutants from agricultural, industrial, military, and municipal sources. These strategies include using algae and a variety of aquatic and terrestrial plants. The book subsequently discusses the use of crops and native plants for phytoremediation, and how phytoremediation efforts impact the rhizosphere. After having finished the book, readers will be able to directly adapt the strategies described here for their specific purposes. .
    Type of Medium: Online Resource
    Pages: VIII, 367 p. 38 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030000998
    Series Statement: Concepts and Strategies in Plant Sciences,
    URL: https://doi.org/10.1007/978-3-030-00099-8
    DOI: 10.1007/978-3-030-00099-8
    DDC: 580
    Language: English
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