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  • Books  (173)
  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry  (173)
  • IntechOpen  (173)
  • 2020-2024  (173)
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  • Books  (173)
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  • 2020-2024  (173)
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  • 1
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Biophysical chemistry is one of the most interesting interdisciplinary research fields. Some of its different subjects have been intensively studied for decades. Now the field attracts not only scientists from chemistry, physics, and biology backgrounds but also those from medicine, pharmacy, and other sciences. We aimed to start this version of the book Biophysical Chemistry from advanced principles, as we include some of the most advanced subject matter, such as advanced topics in catalysis applications (first section) and therapeutic applications (second section). This led us to limit our selection to only chapters with high standards, therefore there are only six chapters, divided into two sections. We have assumed that the interested readers are familiar with the fundamentals of some advanced topics in mathematics such as integration, differentiation, and calculus and have some knowledge of organic and physical chemistry, biology, and pharmacy. We hope that the book will be valuable to graduate and postdoctoral students with the requisite background, and by some advanced researchers active in chemistry, biology, biochemistry, medicine, pharmacy, and other sciences.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 2
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: In recent years, great progress has been made in the field of essential oils as scientific research has revealed new insights into the biological benefits, healing properties, and other uses. Interest in their use in various industries, such as medicine, agriculture, food, and cosmetics, has increased. Essential oils have found their place in many applications, thus fueling a wave of scientific research and industrial applications. This book explores these recent developments in detail, revealing new perspectives and applications of essential oils. It combines historical knowledge with the latest research to provide a comprehensive overview of the field. By exploring the ancient legacy of aromatic plants and their traditional medicinal uses, as well as delving into the latest research and industrial applications, this book provides a comprehensive understanding of essential oils and their potential.
    Keywords: thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 3
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 4
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Amino Acid - New Insights and Roles in Plant and Animal provides useful information on new aspects of amino acid structure, synthesis reactions, dietary application in animals, and metabolism in plants. Section 1 includes chapters that describe the therapeutic uses, antiallergic effects, new aspects in the D-amino acid structure, historical background of desmosines, and stereoselective synthesis of ?-aminophosphonic acids. Section 2 presents the role of amino acids in plants, which includes new insights and aspects of D-amino acids, metabolism and transport in soybean, changes during energy storage compound accumulation of microalgae, and determination of amino acids from natural compounds. Section 3 describes the chapters on methodologies and requirement of dietary amino acids for Japanese quails, laying hens, and finishing pigs. The final chapter identifies potential importance of glutathione S-transferase activity for generating resistance to triclabendazole in Fasciola hepatica.
    Keywords: amino acids, biomarkers, bacteria, microalgae, phytochemicals, physiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 5
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or addition of an oxygen radical, resulting in the oxidative damage of polyunsaturated fatty acids (PUFA). PUFAs are more sensitive than saturated fatty acids because of the presence of a double bond adjacent to a methylene group that makes the methylene C-H bond weaker and therefore the hydrogen is more susceptible to abstraction. This leaves an unpaired electron on the carbon, forming a carbon-centered radical, which is stabilized by a molecular rearrangement of the double bonds to form a conjugated diene, which then combines with oxygen to form a peroxy-radical.In pathological situations the reactive oxygen and nitrogen species are generated at higher than normal rates, and as a consequence, lipid peroxidation occurs with deficiency of endogenous antioxidants as alpha-tocopherol deficiency or reduced glutathione. In addition to containing high concentrations of PUFAs and transition metals, biological membranes of cells and organelles are constantly being subjected to various types of damage.This book presents systematic and comprehensive reviews on free radicals and their involvement in lipid peroxidation with special emphasis on their important role in different diseases.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 6
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Lactation is a fascinating process. Research over the last decade has provided new insights into the regulation of mammary gland development and involution. Lactation is the last step in reproduction, and therefore it is linked to reproduction strategy. Photoperiod species such as sheep, or pseudo-ovulatory (at mid-gestation) species as the rodent Lagostomus maximus, are interesting and unique models to study mammary gland physiology. This book also offers updated insights into the mechanisms that control postlactational involution, therefore also providing information to better understand breast cancer. Small noncoding RNA has opened new understanding in gene regulation. In this regard, our knowledge of mammary gland development and milk secretion has increased extremely. This book provides current scientific information on all these interesting topics. It will certainly be of great benefit to those interested in biomedical sciences.
    Keywords: mammary gland, breast cancer, microrna, melatonin, genome editing, cell death ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 7
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Chlorophyll, a green pigment present in almost all plants, algae, and cyanobacteria, is a significant biomolecule essential to photosynthesis, the process by which plants convert light into energy. This book provides a comprehensive and easy-to-understand source of information on the latest developments in chlorophyll research. It is a collection of contributions from leading specialists in the subject. Topics discussed include the medicinal uses of chlorophyll, the electronic structure of chlorophyll monomers and oligomers, and chlorophyll estimate from fluorescence vertical profiles in the ocean.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 8
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Proteomics Technologies and Applications reviews and describes the nature and application of molecules with proteins or peptides, and elucidates and predicts the possible molecular and physiological causes related to changing proteomic profiles. Chapters target various methods and tools available for analysis, detection, separation, quantification, and localization of cell proteomes of a biological system, which are helpful as biomarkers for various disease prognoses and diagnoses.
    Keywords: mass spectrometry, biomarkers, breast cancer, colorectal cancer, melanoma, glioblastoma ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 9
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Stem cells have a prominent role in normal life and also in pathogenesis of disorders. Today, these cells are clinically applicable in hematopoietic stem cell transplantation but expansion of their application in many more disorders needs more work. For safe and effective application of these cells, we need better knowledge of their biology, their interaction with other cells (especially supporting niche cells), growth, maturation and also immigration of stem cells through body in normal and abnormal conditions. Also for clinical application we need to understand better, their separation methods and safe manipulation. This book is written to clarify some aspects of stem cell biology, their characteristics, assessment of damage to cells during ex vivo manipulation and also their role in a model of cancers (chronic myeloid leukemia).
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 10
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Embryonic stem cells are one of the key building blocks of the emerging multidisciplinary field of regenerative medicine, and discoveries and new technology related to embryonic stem cells are being made at an ever increasing rate. This book provides a snapshot of some of the research occurring across a wide range of areas related to embryonic stem cells, including new methods, tools and technologies; new understandings about the molecular biology and pluripotency of these cells; as well as new uses for and sources of embryonic stem cells. The book will serve as a valuable resource for engineers, scientists, and clinicians as well as students in a wide range of disciplines.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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