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  • 1
    Keywords: Neurosciences. ; Pharmacology. ; Anesthesiology. ; Neuroscience. ; Pharmacology. ; Anesthesiology.
    Description / Table of Contents: Chapter 1. Analgosedation -- Chapter 2. Inhalational Anesthetics -- Chapter 3. Intravenous Anesthetic Agents -- Chapter 4. Local Anesthetics -- Chapter 5. Neuromuscular Blocking Drugs (nmbds) -- Chapter 6. Reversal Agents and Antagonists -- Chapter 7. Anticholinergics -- Chapter 8. Anti-epileptic Drugs (aeds) -- Chapter 9. Osmotherapy -- Chapter 10. Antibiotics -- Chapter 11. Anti-viral -- Chapter 12. Antifungal -- Chapter 13. Anticoagulants and Antiplatelets -- Chapter 14. Glucocorticoids -- Chapter 15. Antihypertensives -- Chapter 16. Vasopressors -- Chapter17. Antipsychotics -- Chapter 18. Miscellaneous drugs. .
    Abstract: The pharmacodynamics and pharmacokinetics of several drugs is expected to be known to clinicians and researchers at all times. With advances in sciences and development of newer drugs very frequently, it is very important to keep your knowledge updated at all times. This title is a quick guide to researchers and clinicians for a quick reference. The title is also a vital resource for all streams of neurosciences (neuroanesthesia and neurointensive care) and is much different from a conventional pharmacology titles, being more reader friendly and to the point facilitated with numerous flowcharts and algorithms with each chapter being prepared in a standard structured manner.
    Type of Medium: Online Resource
    Pages: VII, 1074 p. 331 illus., 108 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811535918
    DDC: 612.8
    Language: English
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  • 2
    Keywords: Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Abstract: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Type of Medium: Online Resource
    Pages: XIV, 256 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811943249
    DDC: 612.8
    Language: English
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  • 3
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Neurology . ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Neuroscience. ; Neurology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Description / Table of Contents: Sleep: Basic and Historical Aspects -- Sleep: Findings in Invertebrates and Lower Vertebrates -- Sleep: Evolutionary and Adaptive Changes in Birds and Mammals -- Sleep Loss: What Does it do to our Brain and Body -- Sleep: Neural Optimization as An Ultimate Function for Memory Consolidation -- Sleep: Disorders and Clinical Implications.
    Abstract: This book discusses the evolution of sleep and its possible function in the higher invertebrates and vertebrates, including humans. It describes the current concept of sleep and its functions, based on research on the mammalian system. To date, electrophysiological recordings of the brain waves, muscle activity, and eye movements are the only tools available for characterizing the sleep architecture in the majority of animals. In mammals and birds, only two distinct types of sleep are found – non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. Since the discovery of REM sleep, studies have been performed to understand the purpose of the two distinct sleep states in higher vertebrates (birds and mammals), and how REM sleep was evolved. The book summarizes the role of both REM and NREM sleep in the proper functioning of the brain and body. It covers various aspects of the role of sleep in important physiological processes, including memory consolidation, induction of synaptic plasticity, energy restoration, enhancing immune response, and maturation of neuronal circuitries during early life. Lastly, the book reviews the effects of chronic/acute sleep deprivation on memory consolidation, obesity, and the immune system in animal models and humans.
    Type of Medium: Online Resource
    Pages: XIV, 118 p. 30 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811571756
    DDC: 612.8
    Language: English
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  • 4
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Medicine Research. ; Biology Research. ; Psychology. ; Neuroscience. ; Biomedical Research. ; Behavioral Sciences and Psychology.
    Description / Table of Contents: Chapter 1: Neural Circuits Underlying Innate Fear -- Chapter 2: Neurobiology and Neural Circuits of Aggression -- Chapter 3: Neural Regulation of Feeding Behavior -- Chapter 4: Neural Circuits for Reward -- Chapter 5: Neuronal response and behavioral modulation in social interaction -- Chapter 6: Neural circuit mechanisms that underlie parental care -- Chapter 7: Spatial navigation -- Chapter 8: Neural circuits for sleep-wake regulation.
    Abstract: This book summarizes the latest research findings in the neurocircuitry of innate behaviors, covering major topics such as innate fear, aggression, feeding, reward, social interaction, parental care, spatial navigation, and sleep-wake regulation. For decades, humans have been fascinated by wild animals’ instincts, like the annual two-thousand-mile migration of the monarch butterfly in North American, and the “imprint” behavior of newborn birds. Since these instincts are always displayed in stereotypical patterns in most individuals of a given species, the neural circuits processing such behaviors must be genetically hard-wired in the brain. Recently, with the development of modern techniques, including optogenetics, retrograde and anterograde virus tracing, and in vivo calcium imaging, researchers have been able to determine and dissect the specific neural circuits for many innate behaviors by selectively manipulating well-defined cell types in the brain. This book discusses recent advances in the investigation of the neural-circuit mechanisms underlying innate behaviors.
    Type of Medium: Online Resource
    Pages: IX, 112 p. 13 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811570865
    Series Statement: Advances in Experimental Medicine and Biology, 1284
    DDC: 612.8
    Language: English
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  • 5
    Keywords: Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Abstract: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Type of Medium: Online Resource
    Pages: XV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676062
    DDC: 612.8
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Stem cells. ; Nervous system Regeneration. ; Neuroscience. ; Stem Cell Biology. ; Regeneration and Repair in the Nervous System.
    Description / Table of Contents: 1 Regenerative Therapies in Ischemic Stroke Recovery -- 2 Application of Nanotechnology In Stroke Recovery -- 3 Nanotechnology: A daydream for advanced Imaging, Diagnosis and Therapeutic Approach for Cerebral Ischemia -- 4 Cell-Mediated Neurorestorative Mechanisms Underpinning Beneficial Effects in Ischemic Stroke -- 5 Induced Pluripotent Stem Cells for the Treatment of Neurodegenerative Disease: Current and Future Prospects -- 6 Imaging of Stem Cell Therapy for Stroke and Beyond -- 7 Nano-Medicine Mediated Stem Cell Therapeutics In Stroke -- 8 The Influence of Preconditioning on the Homing Behaviour of Stem Cells -- 9 Role of microRNAs in stroke pathology and recovery -- 10 Exosomes as a diagnostic tool and stem cells exosomes as a promising cell-based cell-free therapeutic tool for ischemic stroke 11 Role of nanomedicine in treating ischemic stroke -- 12 Insights into therapeutic targets in stroke -- 13 Signalling Pathways of Interest for Recovery from Ischemic Stroke.
    Abstract: This book illustrates the importance and significance of regenerative medicine in stroke recovery. It discusses stem-cell-based treatment strategies and offers mechanistic insights into their role in neurological recovery. It also examines the challenges and advances in using adult stem cells for enhanced therapeutic efficacy. Further, it presents the strategies as well as the strengths and weaknesses of various delivery methods to administer stem cells in ischemic stroke. It examines the role of non-coding RNA in our understanding the stroke pathogenesis, their regulatory role in ischemic stroke and potential as biomarkers and therapeutic targets. Lastly, it explores exosomes in the treatment of stroke, and the underlying mechanism of their action as therapeutic vectors for stroke. Given its scope, it is an excellent resource for neurologists, neuroscientists and researchers involved in regenerative therapy for stroke.
    Type of Medium: Online Resource
    Pages: XIII, 353 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811685620
    DDC: 612.8
    Language: English
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  • 7
    Keywords: Neurosciences. ; Biotechnology. ; Cognitive psychology. ; Nonlinear Optics. ; Neuroscience. ; Biotechnology. ; Cognitive Psychology. ; Nonlinear Optics.
    Description / Table of Contents: Neural Dynamics in Motor and Sensory Systems and in Cognitive Functions -- Cognitive Network and Multi-Scale Neural Network Dynamics -- Neuroengineering, Neuroinformation and Brain Computer Interaction -- Modelling Higher-Order Functions and Dysfunctions -- Oscillation, Synchronization, Neural Plasticity, and Coordination Dynamics from Neural to Social Systems.
    Abstract: This book contains original articles submitted to the Seventh International Conference on Cognitive Neurodynamics (ICCN 2019). The brain is an endless case study of a complex system characterized by multiple levels of integration, multiple time scales of activity, and multiple coding and decoding properties. The contribution of several disciplines, mathematics, physics, computer science, neurobiology, pharmacology, physiology, and behavioral and clinical sciences, is necessary in order to cope with such seemingly unattainable complexity that transforms the experimental information into a tricky puzzle which hides the correspondence with model predictions. This conference gathered active participants to discuss ideas and pose new questions from different viewpoints, ranging from single neurons and neural networks to animal/human behavior in theoretical and experimental studies. The conference is organized with plenary lectures, mini-symposia, interdisciplinary round tables, and oral and poster sessions.
    Type of Medium: Online Resource
    Pages: XIX, 293 p. 97 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811603174
    Series Statement: Advances in Cognitive Neurodynamics,
    DDC: 612.8
    Language: English
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  • 8
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry.
    Description / Table of Contents: 1.How Immune-inflammatory processes link neurodegenerative and psychiatric disorders -- 2.Gut-Microbiota-Brain Axis: pathophysiological mechanism in neuropsychiatric disorders -- 3.Microbiome- induced autoimmunity and novel therapeutic intervention -- 4.The key role of microlia and circulating monocytes in etipathology neuropsychiatric disorders -- 5.Neuro-immuno-epigenetics of prenatal psychological stress -- 6.C-reactive protein (CRP): a potent inflammation biomarker in psychiatric disorders -- 7.Neuroinflammation, neurognesis and neuroprotection in schizophrenia -- 8.Autoimmue psycosis: concept, clinical manifestation and management -- 9.Stress, autonomic nervous system and kynurenine pathway in major depression -- 10.Brain-gut-microbiome axis in major depression : novel therapeutic approach -- 11.Glial-Neuronal Interaction in Synapses: A Possible Mechanism of the Pathophysiology of Bipolar Disorder -- 12.Neuroimmaging of inflammation in depression and anxiety disorders -- 13.Neuroinflammation and immune-kynureinine pathway in anxiety disorders -- 14.Inflammatory-mediated responses in development of neurogeneartive diseases -- 15.The connection between gut-brain axis and PTSD -- 16.Eating disorders : Gut microbiota-immune-brain interactions -- 17.Sleep-immune crosstalk and sleep disorders -- 18.Obsessive-compulsive disorder: immuno-inflammatory disorder? -- 19.Cytokine, neuroinflammation and neurodeneration in Alzheimer’s disease -- 20.Molecular imaging of neuroinflammation in Alzheimer's disease and MCI -- 21.The role of N-Methyl-D-Aspartate Receptor Neurotransmission and mictobiota in Alzheimer’s disease -- 22.Neuroglial activation and neuroinflammation in the brain of patients with autism -- 23.Suicide and inflammation -- 24.Anti-inflammatory effect of Traditional Chinese Medicine on the concept of Mind-body interface -- 25.Anti-inflammatory therapy as a promising target in neupsychiatric disorders.
    Abstract: This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.
    Type of Medium: Online Resource
    Pages: XVII, 554 p. 28 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811973765
    Series Statement: Advances in Experimental Medicine and Biology, 1411
    DDC: 612.8
    Language: English
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  • 9
    Keywords: Neurosciences. ; Materials Analysis. ; Imaging systems. ; Nervous system Diseases. ; Nervous system Radiography. ; Neuroscience. ; Imaging Techniques. ; Neurological Disorders. ; Neuroradiology.
    Description / Table of Contents: Optical coherence tomography in brain gliomas detection and peritumoral white matter state evaluation -- Two Photon Fluorescence Lifetime Imaging of Reduced nicotinamide adenine dinucleotide in Brain Research -- Types of Raman Scattering Techniques for Neurodegenerative Diseases -- Drosophila brain advanced multiphoton imaging -- Myelin imaging -- Brainbow: Principle, Technique and Applications -- Photoacoustic Imaging of Brain -- Photodynamic therapy of brain diseases -- Advanced Magnetic Resonance Imaging (MRI) of Brain -- Indirect imaging -- Multimodal Noninvasive Imaging Strategies for Clinically Monitoring Degenerative Disorders of the Brain -- Machine learning approach in brain imaging -- Transgenic Brain mapping Techniques in Drosophila melanogaster -- Behavioural phenotyping to study cognitive and non-cognitive symptoms in the rodent model of Alzheimer's disease.
    Abstract: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.
    Type of Medium: Online Resource
    Pages: XII, 257 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913525
    DDC: 612.8
    Language: English
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  • 10
    Keywords: Neurosciences. ; Public health. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Public Health. ; Biomedical Research.
    Description / Table of Contents: 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection.
    Abstract: This book examines the correlation of the coronavirus disease-19 [CE1] [AAS2] (COVID-19) infection with sleep, circadian rhythm, and sleep disorders. The chapters of the book explore sleep problems during the COVID-19 pandemic and its association with psychological distress and also review the prevalence of clinical cases of insomnia, anxiety, and depression in COVID-19 patients. The book further presents the correlation between sleep, circadian rhythms, and immunity that contributes toward more severe COVID-19. It summarizes the evidence on the interplay between circadian biology, sleep, and COVID-19. The chapters of the book discuss the relationship between obstructive sleep apnea (OSA) and adverse COVID-19 outcomes. Towards the end, the book presents studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin and provides mechanistic insights into the potential therapeutic use of melatonin during the SARS-CoV-2 infection. The last chapter describes the publication output of sleep-related research during the pandemic and provides an overview and trends on sleep and covid-19 publication output. This book is an excellent source for neurologists, sleep specialists, and public health specialists.
    Type of Medium: Online Resource
    Pages: XXVI, 430 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819902408
    Series Statement: Progress in Sleep Research,
    DDC: 612.8
    Language: English
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