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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Translational Neuroscience of Speech and Language Disorders: State of the Art. -2. Translational Neuroscience of Aphasia and Adult Language Rehabilitation. -3. Treatment and intervention approaches for the improvement of language abilities in neurodegenerative diseases -- 4. Neural and Genetic Mechanisms of Dyslexia -- 5. The role of memory systems in neurodevelopmental disorders of language -- 6. Transcranial direct current stimulation (tDCS) and Language/Speech: Can patients benefit from a combined therapeutic approach? -- 7. Transcranial Magnetic Stimulation in Aphasia Rehabilitation -- 8. The Cerebellum: A Therapeutic Target in Treating Speech and Language Disorders -- 9. Navigated rTMS for Mapping the Language Network in Preoperative Settings: Current Status and Future Prospects -- 10. Presurgical Language fMRI in Epilepsy: An Introduction -- 11. Lesion-symptom mapping in speech and language disorders: a translational perspective.
    Abstract: This edited volume provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative conditions on speech and language. It brings together contributions from several leading experts in a markedly broad range of disciplines, including Speech and Language Therapy, Neuropsychology and Neurology, but also Neurosurgery, Neuroimaging and Neurostimulation, as well as Engineering and Genetics.
    Type of Medium: Online Resource
    Pages: XVII, 290 p. 18 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030356873
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Anatomy. ; Internal medicine. ; Cytology. ; Biochemistry. ; Neuroscience. ; Anatomy. ; Internal Medicine. ; Cell Biology. ; Biochemistry.
    Description / Table of Contents: Neurosecretion: A Historical Overview -- Neurosecretion: Hypothalamic Somata versus Neurohypophysial Terminals -- Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus -- Somato-Dendritic Secretion of Neuropeptides -- Neurosecretory Vesicles: Structure, Distribution, Release and Breakdown -- Molecular Controls on Regulated Neurotransmitter and Neurohormone Secretion -- Secretory Astrocytes -- Action Potential-Induced Ca2+ Influx for Both Acute and Sustained Insulin Secretion in Pancreatic Beta Cells -- Plasticity in the Morphology of Lactotrophs and Folliculo-Stellate Cells and Prolactin Secretion -- Neuroendocrine and Metabolic Regulation of Plasma Growth Hormone Secretory Profiles -- Role of the TWIK-Related Potassium (TREK)-1 Channels in the Regulation of Adrenocorticotropic Hormone (ACTH) Secretion from Pituitary Corticotropes -- How Do Bacterial Neurotoxins Affect Neurosecretion? -- Secretory Mechanisms in Paramecium.
    Abstract: How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley.
    Type of Medium: Online Resource
    Pages: XIII, 307 p. 65 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030229894
    Series Statement: Masterclass in Neuroendocrinology, 8
    DDC: 612.8
    Language: English
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  • 3
    Keywords: Biotechnology. ; Plant diseases. ; Microbial ecology. ; Bacteria. ; Biology Technique. ; Biotechnology. ; Plant Pathology. ; Microbial Ecology. ; Bacteria. ; Biological Techniques.
    Description / Table of Contents: Chapter 1. Hairy Roots Biotechnology Unzipped: A Journey of Reality and Promises -- Chapter 2. Hairy Roots as a Source of Tropane Alkaloids -- Chapter 3. Induction, Metabolite Analysis and Transgenesis of Hairy Roots From Coleus Forskohlii -- Chapter 4. Establishment of Hairy Roots of Endangered Himalayan Plantswertiachirata: A Sustainable Alternative to Extraction from Nature -- Chapter 5. A Protocol for the Selection of Spontaneous Variants From Established Catharanthusroseus Hairy Root Cultures -- Chapter 6. Strategies for the Optimization of Culture Conditions for Increasing Metabolite Production Through Hairy Root Cultures. Monoterpenoid Indole Alkaloid Production in Catharanthus Roseus Hairy Roots -- Chapter 7. Protocol for Enhanced Withaferin-a Production in Elicited Withania Somnifera (l.)Dunal Hairy Root Cultures -- Chapter 8. Establishment of Hairy Root Cultures of Pentalinonandrieuxii for the Production of Betulinic Acid -- Chapter 9. Tropane Alkaloid Production by the Establishment Of Hairy Root Cultures of Brugmansia Candida and Elicitation -- Chapter 10. Elicitation as an Essential Strategy For Enhancing Anthraquinone Accumulation In Hairy Root Cultures of Rubia Tinctorum -- Chapter 11. Establishment of Hairy Root Cultures for the Production of Biopharmaceuticals and Optimization of Methods for Recombinant Protein Secretion In The Culture Medium -- Chapter 12. An Improved Protocol for Agrobacterium Rhizogenes-Mediated Transformation of Recalcitrant Plants for Root Biology Studies: A Case Study of Tea Plants (Camellia Sinensis Var. Sinensis) -- Chapter 13 Functional Analysis of Plant Genes Related to Arbuscular Mycorrhiza Symbiosis Using Agrobacterium Rhizogenes-Mediated Root Transformation and Hairy Root Production -- Chapter 14. Functional Characterization of Genes Involved in Legume Nodulation Using Hairy Root Cultures -- Chapter 15. Fluidigm Biomark Diagnostic Panel for Analysis of the Expression of Nicotiana Tabacum Genes, Associated with Alkaloid Synthesis. .
    Abstract: The book discusses the various methods and protocols available in hairy root culture-based research. The utilization of Agrobacterium mediated genetic transformation and establishment of hairy root cultures has paved the way for large-scale secondary metabolite production in medicinal plants. Presenting recent research and offering insights from eminent research groups, the book covers a range of topics related to hairy root-based applications, including (i) establishment of hairy roots and native production of SM (ii) yield enhancement strategies for increased SM production, like elicitation (iii) hairy roots as a tool for value-added applications such as plant-microbe interaction, characterization of plant genes and root biology studies. As such it is an informative guide and experimental manual for researchers in diverse fields of plant biology.
    Type of Medium: Online Resource
    Pages: XIV, 237 p. 47 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811540554
    Series Statement: Rhizosphere Biology,
    DDC: 660.6
    Language: English
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  • 4
    Keywords: Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Description / Table of Contents: Ch 1: Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging -- Ch 2: Genetic and Molecular Aspects of the Aging Auditory System -- Ch 3: The Aging Cochlea and Auditory Nerve -- Ch 4: Age-Related Changes in the Auditory Brainstem and Inferior Colliculus -- Ch 5: Age related changes in the primate auditory cortex -- Ch 6: The Aging Auditory System: Electrophysiology -- Ch 7: Age-Related Changes in Segregation of Sound Sources -- Ch 8: Causes and Consequences of Age-Related Hearing Loss -- Ch 9: Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences -- Ch 10: Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener -- Ch 11: Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention -- Ch 12: Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss.
    Abstract: This volume provides contemporary discussions on new developments in aging research. It serves as an important update on the current state of research on the aging auditory system. Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging Karen S. Helfer and Edward L. Bartlett Genetic and Molecular Aspects of the Aging Auditory System Shinichi Someya and Mi-Jung Kim The Aging Cochlea and Auditory Nerve Kevin K. Ohlemiller and Christopher Spankovich Age-Related Changes in the Auditory Brainstem and Inferior Colliculus Josef Syka Age-Related Changes in the Primate Auditory Cortex Gregg Recanzone The Aging Auditory System: Electrophysiology Kelly C. Harris Age-Related Changes in Segregation of Sound Sources Frederick J. Gallun and Virginia Best Causes and Consequences of Age-Related Hearing Loss Jennifer A. Deal, Nicholas S. Reed, Emily C. Pedersen, and Frank R. Lin Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences Sandra Gordon-Salant, Maureen J. Shader, and Arthur Wingfield Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener Stefanie E. Kuchinsky and Kenneth I. Vaden, Jr. Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention Larry E. Humes, M. Kathleen Pichora-Fuller, and Louise Hickson Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss Robert D. Frisina, Carlos J. Cruz, Tanika T. Williamson, Xiaoxia Zhu, and Bo Ding .
    Type of Medium: Online Resource
    Pages: XVII, 323 p. 62 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030493677
    Series Statement: Springer Handbook of Auditory Research, 72
    DDC: 612.8
    Language: English
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  • 5
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Atoms. ; Molecules. ; Biotechnology. ; Atomic, Molecular and Chemical Physics.
    Description / Table of Contents: Photonic crystals for biomolecule sensing applications -- Recent advances in Surface Plasmon Resonance for biosensing applications and future prospects -- Surface-enhanced Raman Scattering for biology and medicine -- Nanophotonic techniques for single cell analysis -- Biointerface Characterization by Nonlinear Optical Spectroscopy -- Chemiluminescence and its biomedical applications -- Luminescent Conjugated Polymer Dots for Biomedical Applications -- Dark-Field Hyperspectral Imaging (DF-HSI) Modalities for Characterization of Single Molecule and Cellular Processes -- Additive Manufacturing Technologies based on Photopolymerization.
    Abstract: This book summarizes the latest advances in nanophotonics for biomedical applications, including biomolecular sensing and imaging, additive fabrications, and biophotonics. The engineering of nanophotonics will have significant impacts on the life sciences and medicine alike. Given its scope, the book offers a valuable asset for researchers, scientists, engineers, and graduate students in the fields of biomedical engineering, electrical engineering, materials sciences, optics, biology, and medicine.
    Type of Medium: Online Resource
    Pages: V, 282 p. 160 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811561375
    DDC: 660.6
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Computer vision. ; Radiology. ; Biotechnology. ; Computer Vision. ; Radiology.
    Description / Table of Contents: Introduction -- Preliminaries -- Fuzzy spatial objects (fuzzy geometry and topology, set theoretic operations) -- Mathematical morphology -- Distances and similarities between fuzzy sets -- Machine learning in image processing and understanding -- Fusion -- Spatial relations -- Structural representations.
    Abstract: This book provides a thorough overview of recent methods using higher level information (object or scene level) for advanced tasks such as image understanding along with their applications to medical images. Advanced methods for fuzzy image processing and understanding are presented, including fuzzy spatial objects, geometry and topology, mathematical morphology, machine learning, verbal descriptions of image content, fusion, spatial relations, and structural representations. For each methodological aspect covered, illustrations from the medical imaging domain are provided. This is an ideal book for graduate students and researchers in the field of medical image processing. This book also: Enriches reader understanding of the latest fuzzy sets methods using higher level information (object or scene level) for advanced tasks, such as image understanding Shares many insights into fuzzy spatial objects, including fuzzy geometry and topology as well as set theoretical operations Covers in detail machine learning in image processing and understanding, with special focus on clustering, classification, and basic and advanced fuzzy methods .
    Type of Medium: Online Resource
    Pages: XIII, 302 p. 97 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031194252
    DDC: 660.6
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Water. ; Hydrology. ; Biotic communities. ; Social sciences. ; Humanities. ; Environmental management. ; Freshwater and Marine Ecology. ; Water. ; Ecosystems. ; Humanities and Social Sciences. ; Environmental Management.
    Description / Table of Contents: Part I. Introduction -- Chapter 1. Southern Baltic Coastal Systems Analysis: Questions, Conceptions and Red Threads -- Chapter 2. Coastal Ecosystems from a Social-Ecological Perspective -- Part II. Ecological Structures and Functions of the German Baltic Sea Coast -- Chapter 3. The Abiotic Background: Climatic, Hydrological and Geological Conditions of the Southern Baltic -- Chapter 4. Geological and Sedimentary Conditions -- Chapter 5. Environmental Conditions at the Coast: The Terrestrial Ecosystems -- Chapter 6. Environmental Conditions at the Coast: Shoreline Ecosystems -- Chapter 7. Ecosystem and Landscape Functions of the Coast: Recent Research Results -- Chapter 8: Benthic Habitats and Their Inhabitants -- Part III. Ecological Structures and Functions of Coastal Water and Offshore Ecosystems -- Chapter 9. Introducing the Ecological Aspects -- Chapter 10. Baltic Sea Aquatic Ecosystems in a Gradient from Land to Open Sea -- Chapter 11. Comparison of Abiotic Parameters and Dominant Primary Producers Between the Two Main Investigation Areas -- Chapter 12. Short-Term Variability, Long-Term Trends and Seasonal Aspects in the Darß-Zingst Bodden Chain -- Chapter 13. Carbon Fluxes/Food-Webs: Effect of Macrophytes on Food Web Characteristics in Coastal Lagoons -- Chapter 14. Ecological Structure in Benthic Habitats of Offshore Waters -- Chapter 15. Patterns of Bioturbation and Associated Matter Fluxes -- Chapter 16. Seasonal Aspects and Short-Term Variability of the Pelagic Offshore Ecosystems -- Chapter 17. Long-Term Trends of the Offshore Ecosystems -- Chapter 18. Nutrient and Limitation Regimes in Coastal Water Ecosystems -- Part IV. Combining the Aspects: Ecosystem Service Assessment -- Chapter 19. The Human Factor: Coastal Social-Ecological Systems -- Chapter 20. Introduction: The Concept of Ecosystem Service Assessment Applied to Coastal Systems -- Chapter 21. The Missing Links in Ecosystem Service Research -- Chapter 22. Eudaimonic Valuation of Cultural Ecosystem Services -- Chapter 23. Economic Valuation of Cultural Ecosystem Services -- Chapter 24. Spatial Ecosystem Service Assessment Across the Land-Sea-Interface -- Chapter 25. Temporal Changes in Aquatic Ecosystem Services Provision: Approach and Examples -- Chapter 26. Assessing Temporal Changes in Ecosystem Service Provisions: Conceiving Future Pathways -- Part V. Synthesis: Assessment as a Tool for Managing Coastal Ecosystems? -- Chapter 27. Applying the Integrated Approach -- Chapter 28. Mechanisms of Ecosystem Service Production: An Outcome of Ecosystem Functions and Ecological Integrity in Coastal Lagoons -- Chapter 29. Ecosystem Service Assessment in European Coastal and Marine Policies -- Chapter 30. Ecosystem Services and Sustainable Development: The Case for Strong Sustainability -- Chapter 31. Concluding Remarks.
    Abstract: This book gives an overall analysis of the current knowledge status about structures, functions, utilization for German Baltic coast ecosystems. The main focus of this book is on the aquatic area, but land/sea interactions as well as river outfalls are included as well. Characteristic for this book is the inclusion of social science aspects. Approximately one third of its extent will be about the ecosystem services. In this segment the results of the last 6 years are presented in which a comprehensive quantification of the social relevance of ecosystems was carried out covering the entire area of the German Baltic Sea. This part builds directly on the results of scientific investigations and are in relation to social ideals. The assessment will not only be economically and ethically but also the mechanisms that are used for the valorisation of the ecosystem services will be evaluated. Both sub-areas, the classic natural science part as well as the part of social science aspects, deal with the changes caused by increasing anthropogenic influence and social (including demographic) changes. This will be among others in the sense of an exemplary historical outline. The final chapter of the synthesis therefore not only presents a summary of the level of knowledge gained and a deduction of the research needs. It further contains a presentation of the application aspects resulting from the analysis of the social relevance gained from basic scientific research. The book is aimed at scientists (and students) of natural, life and social sciences, analysing functioning and structures of coastal ecosystems with regard to sustainable use and nature protection, including aspects of coastal protection. Besides, it is thought to become a reference for all levels of decision makers and stakeholders in coastal and marine management of the Baltic and North Sea region, providing also a blueprint for system analysis respecting for societal as well as biological aspects world-wide.
    Type of Medium: Online Resource
    Pages: XV, 387 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031136825
    Series Statement: Ecological Studies, Analysis and Synthesis, 246
    DDC: 577.6
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Human physiology. ; Neurology . ; Life sciences. ; Physiology. ; Neuroscience. ; Human Physiology. ; Neurology. ; Life Sciences. ; Animal Physiology. ; Life Sciences.
    Description / Table of Contents: Part I: HISTORY -- Chapter 1: Transmissible Spongiform Encephalopathy: from its beginnings to Daniel Carleton Gajdusek -- Part II: GENERAL ASPECTS OF PRIONS -- Chapter 2: The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein -- Chapter 3: Mammalian Prion Structures -- Chapter 4: Insoluble Cellular Prion Protein and Other Neurodegeneration-related Misfolded Protein Aggregates in the Brain of Asymptomatic Individuals -- Part III: CONVERSION AND STRAIN OF PRIONS -- Chapter 5: Prion Conversion and Deformed Templating -- Chapter 6: Prion Strain Interference -- Chapter 7: Molecular Mechanisms Encoding Strains of Prions and Prion-Like Misfolded Proteins -- Chapter 8: Cofactor Involvement in Prion Propagation -- Chapter 9: Prion Protein Conversion and Lipids -- Part IV: ENVIRONMENT AND TRANSMISSION OF PRIONS -- Chapter 10: Prions in the Environment -- Chapter 11: Environmentally Acquired Transmissible Spongiform Encephalopathy -- Chapter 12: Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion -- Chapter 13: Species Barriers in Prion Disease -- Part V: MODELLING OF PRIONS -- Chapter 14: Modeling the Cell Biology of Prions -- Chapter 15: Transgenic Mice Modelling in Prion Diseases -- Chapter 16: Stem Cell Models in Prion Research -- Chapter 17: Drosophila Models of Prion Diseases -- Part VI: HUMAN PRION DISEASES AND OTHER PATHOLOGIES -- Chapter 18: Human Sporadic Prion Diseases -- Chapter 19 Genetic Creutzfeldt-Jakob and Gerstmann-Sträussler-Scheinker Diseases -- Chapter 20: Glycoform-selective Prions in Sporadic and Inherited Variably Protease-sensitive Prionopathies -- Chapter 21: The Spectrum of Tau Pathology in Human Prion Disease -- Chapter 22: Prion Protein Complex with mGluR5 Mediates Amyloid-ß Synaptic Loss in Alzheimer’s Disease -- Chapter 23: Prion and Cancers -- Chapter 24: Protective Role of Cellular Prion Protein in Tissue Ischemic/Reperfusion Injury -- Part VII: ANIMAL PRION DISEASES -- Chapter 25: Bovine Spongiform Encephalopathy -- Chapter 26: Classical and Atypical Scrapie in Sheep and Goats -- Chapter 27: Research models for studying chronic wasting disease -- Part VIII: YEAST PRIONS -- Chapter 28: Introduction to Yeast and Fungal Prions -- Chapter 29: Yeast Prions Are Folded, In-Register Parallel Amyloids Subject to Multiple Anti-prion Systems -- Part IX: DIAGNOSIS AND HUMAN PRION SURVEILLANCE -- Chapter 30: Real-time quaking-induced conversion (QuIC) assays for the detection and diagnosis of human prion diseases -- Chapter 31: Protein Misfolding Cyclic Amplification -- Chapter 32: Skin Misfolded Proteins as Biomarkers for Diagnosis of Prion and Prion-like Diseases -- Chapter 33: Diagnosis of Prion Disease: Conventional Approaches -- Chapter 34: Human Prion Disease Surveillance -- Part X: TREATMENT -- Chapter 35: Overview on Treatment of Prion Diseases and Decontamination of Prions -- Chapter 36: Gene Therapy Strategies for Prophylactic and Therapeutic Treatments of Human Prion Diseases -- Chapter 37: Immunomodulation.
    Abstract: Transmissible spongiform encephalopathies (TSE), now known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains the most authoritative views about the past, present, and future of prions and prion diseases covering fresh perspectives on important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.
    Type of Medium: Online Resource
    Pages: XII, 793 p. 81 illus., 62 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031205651
    DDC: 612.8
    Language: English
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  • 9
    Keywords: Neurosciences. ; Biomedical engineering. ; Nanotechnology. ; Biophysics. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Nanoengineering. ; Bioanalysis and Bioimaging. ; Biological Imaging.
    Description / Table of Contents: Part 1 -- Optically-Pumped Magnetometers Compatible with Large Transient Magnetic Fields -- Small animal biomagnetism applications -- Supine OPM-MEG in Multi-layer Cylindrical Shield -- Ambulatory MEG Arrays -- Part 2 -- "Tri-axial helium-4 optically-pumped -- magnetometers for MEG" -- Person-Sized Magnetoencephalography Systems with Optically Pumped Magnetometers -- On-scalp MEG with High-Tc SQUIDs -- "Fiber Coupled OPM in Purely Coil -- Shielded Environment" -- SERF-OPM usability for MEG in two-layer shielded rooms -- Turning OPM-MEG into a Wearable Technology -- Part 3 -- OPM Gradiometer for Magnetorelaxometry -- Unshielded High Bandwidth Magnetorelaxometry of Magnetic Nanoparticles with Optically Pumped Magnetometers -- Adult Magnetocardiography: Principles and Clinical Practice -- Fetal Magnetocardiography with OPMs -- Emerging MR sensors for biomagnetic measurements -- Index.
    Abstract: This contributed volume reviews the latest advances in all the new technologies currently developed for MagnetoEncephaloGraphy (MEG) recordings, as well as sensor technologies and integrated sensor arrays for on-scalp MEG. The book gives an account of the first MEG imaging studies and explores the new field of feasible, experimental paradigms of on-scalp MEG. This is an ideal book for engineers, researchers, and students in the neurosciences interested in MEG imaging. .
    Type of Medium: Online Resource
    Pages: IX, 315 p. 104 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031053634
    DDC: 612.8
    Language: English
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  • 10
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Introduction Food and Brain -- 2. Food and Behavior -- 3. Food and Psychological Wellbeing -- 4. Food and Cognition -- 5. Autism and Food -- 6. Healthy Brains: Types of Food and their Active Pharmacological Ingredients -- 5. Dieting: Importance of Diet and Diet Types -- 6. Nutrigenomics -- 7. Epigenetics -- 8. Gut Microbiota (microbiome) -- 9. Personalized Nutrition -- 10. Vegetables -- 11. Fruits -- 12. Nuts, Seeds and Spices -- 13. Grains [Oats, Barley & Quinoa] -- 14. Seafood [fish like Salmon, Oyster, Sea vegetables (algae)] -- 15. Other -- 16. Autism Management through Food and Diet -- 17. Personalized Nutrition Therapy.
    Abstract: The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.
    Type of Medium: Online Resource
    Pages: XX, 693 p. 111 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030304027
    Series Statement: Advances in Neurobiology, 24
    DDC: 612.8
    Language: English
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  • 11
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Cytology. ; Nanoscience. ; Biotechnology. ; Cell Biology. ; Nanophysics.
    Description / Table of Contents: Chapter 1: Introduction: Fluorescent materials for cell imaging -- Chapter 2: Semiconductor quantum dots for cell imaging -- Chapter 3: Carbon nanodots for cell imaging -- Chapter 4: Silicon nanoparticles for cell imaging -- Chapter 5: Fluorescent metal nanoclusters for bioimaging -- Chapter 6: Lanthanide-based upconversion nanoparticles for bioimaging applications -- Chapter 7: Conjugated polymers and polymer dots for cell imaging -- Chapter 8: Aggregation-induced emission (AIE) probes for cell imaging -- Chapter 9: Luminescent coordination compounds for cell imaging.
    Abstract: This book focuses on the latest fluorescent materials for cell imaging. Cell imaging is a widely used basic technique that helps scientists gain a better understanding of biological functions through studies of cellular structure and dynamics. In the past decades, the development of a variety of new fluorescent materials has significantly extended the applications of cellular imaging techniques. This book presents recently developed fluorescent materials, including semiconductor quantum dots, carbon dots, silicon nanoparticles, metal nanoclusters, upconversion nanoparticles, conjugated polymers/polymer dots, aggregation-induced emission (AIE) probes, and coordination compounds, used for various cellular imaging purposes. It will appeal to cell biologists and other researchers in academia, industry and clinical settings who are interested in the technical development and advanced applications of fluorescence imaging in cells, tissues and organisms to explore the mechanisms of biological functions and diseases.
    Type of Medium: Online Resource
    Pages: V, 247 p. 140 illus., 128 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811550621
    DDC: 660.6
    Language: English
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  • 12
    Keywords: Neurosciences. ; Pharmacology. ; Anesthesiology. ; Neuroscience. ; Pharmacology. ; Anesthesiology.
    Description / Table of Contents: Chapter 1. Analgosedation -- Chapter 2. Inhalational Anesthetics -- Chapter 3. Intravenous Anesthetic Agents -- Chapter 4. Local Anesthetics -- Chapter 5. Neuromuscular Blocking Drugs (nmbds) -- Chapter 6. Reversal Agents and Antagonists -- Chapter 7. Anticholinergics -- Chapter 8. Anti-epileptic Drugs (aeds) -- Chapter 9. Osmotherapy -- Chapter 10. Antibiotics -- Chapter 11. Anti-viral -- Chapter 12. Antifungal -- Chapter 13. Anticoagulants and Antiplatelets -- Chapter 14. Glucocorticoids -- Chapter 15. Antihypertensives -- Chapter 16. Vasopressors -- Chapter17. Antipsychotics -- Chapter 18. Miscellaneous drugs. .
    Abstract: The pharmacodynamics and pharmacokinetics of several drugs is expected to be known to clinicians and researchers at all times. With advances in sciences and development of newer drugs very frequently, it is very important to keep your knowledge updated at all times. This title is a quick guide to researchers and clinicians for a quick reference. The title is also a vital resource for all streams of neurosciences (neuroanesthesia and neurointensive care) and is much different from a conventional pharmacology titles, being more reader friendly and to the point facilitated with numerous flowcharts and algorithms with each chapter being prepared in a standard structured manner.
    Type of Medium: Online Resource
    Pages: VII, 1074 p. 331 illus., 108 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811535918
    DDC: 612.8
    Language: English
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  • 13
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Animal migration. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Biodiversity. ; Animal Migration.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. European pearl mussel: background information and literature review -- Chapter 3. Materials and methods -- Chapter 4. Results -- Chapter 5. Discussion -- Chapter 6. Conclusions.
    Abstract: The monograph focuses on the European freshwater pearl mussel Margaritifera margaritifera, which is an endangered bivalve species. Most of its populations in the Russian section of the Baltic Sea basin had never been studied, although they were known in the past to the pearl fishers. “Rediscovery” included search for the previously unknown populations, revealing the facts of population extinctions, analysis of negative impacts, elaboration of conservation measures, and revealing of regularities in distribution. Patterns of land use and river management were analyzed. The procedure of “rediscovery” was applied for other animal species of Northwest Russia, which are threatened on a global scale – thick-shelled mussel, Unio crassus; curlew Numenius arquata; black-tailed godwit, Limosa limosa; Northern Lapwing, Vanellus vanellus; European mink, Mustela lutreola; pond bat, Myotis dasycneme; Atlantic sturgeon, Acipenser sturio; and broad-clawed crayfish, Astacus astacus. The methods and principles of conservation studies were discussed. The obtained data were analyzed with respect to current global change of biosphere. The book will appeal to specialists dealing with conservation studies and activities such as red lists, river protection, and conservation of endangered species. Moreover, a part of the book represents an interest for biogerontology as it presents discredit of the popular concept on “negligible senescence.” The data on distribution of some animals in Russia will be interesting in terms of zoology and biogeography, as they are not yet sufficiently represented in the international editions. The book can be used as supplemental reading for courses in biological invasions, ecology and conservation, and biodiversity. The work also contains chapters on global processes (deforestation, desertification, river degradation) and can therefore also be used for general courses in environmental sciences.
    Type of Medium: Online Resource
    Pages: XI, 246 p. 88 illus., 87 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030662554
    DDC: 577.6
    Language: English
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  • 14
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Evolution (Biology). ; Biodiversity. ; Animal culture. ; Plant genetics. ; Climatology. ; Freshwater and Marine Ecology. ; Evolutionary Biology. ; Biodiversity. ; Animal Science. ; Plant Genetics. ; Climate Sciences.
    Description / Table of Contents: Part I: Introduction -- Marine Population Genomics: Challenges and Opportunities -- Part II: Marine Microbes -- Part III: Genetic Diversity, Population Structure, and Biogeography -- Population Genomics of Marine Zooplankton -- Population Genomics of Early-Splitting Lineages of Metazoans -- Population Genomics and Biogeography of the Northern Acorn Barnacle (Semibalanus balanoides) Using Pooled Sequencing Approaches -- Part IV: Seascape Genomics -- Seascape Genomics: Contextualizing Adaptive and Neutral Genomic Variation in the Ocean Environment -- Part V: Adaptation, Acclimation, and Speciation -- Clinal Adaptation in the Marine Environment -- The Population Genomics of Parallel Adaptation: Lessons from Threespine Stickleback -- Mechanisms of Adaptive Divergence and Speciation in Littorina saxatilis: Integrating Knowledge from Ecology and Genetics with New Data Emerging from Genomic Studies -- Ecological Speciation in Corals -- Environmental Epigenomics and Its Applications in Marine Organisms -- Part VI: Protection, Conservation, and Management of Marine Organisms -- Marine Invasion Genomics: Revealing Ecological and Evolutionary Consequences of Biological Invasions -- Population Genomics Applied to Fishery Management and Conservation -- Marine Conservation and Marine Protected Areas -- Index.
    Abstract: Population genomics has provided unprecedented opportunities to unravel the mysteries of marine organisms in the oceans' depths. The world's oceans, which make up 70% of our planet, encompass diverse habitats and host numerous unexplored populations and species. Population genomics studies of marine organisms are rapidly emerging and have the potential to transform our understanding of marine populations, species, and ecosystems, providing insights into how these organisms are evolving and how they respond to different stimuli and environments. This knowledge is critical for understanding the fundamental aspects of marine life, how marine organisms will respond to environmental changes, and how we can better protect and preserve marine biodiversity and resources. This book brings together leading experts in the field to address critical aspects of fundamental and applied research in marine species and share their research and insights crucial for understanding marine ecosystem diversity and function. It also discusses the challenges, opportunities and future perspectives of marine population genomics. .
    Type of Medium: Online Resource
    Pages: XVI, 456 p. 75 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030379360
    Series Statement: Population Genomics,
    DDC: 577.6
    Language: English
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  • 15
    Keywords: Biotechnology. ; Food science. ; Microbiology. ; Biotechnology. ; Food Science. ; Microbiology.
    Description / Table of Contents: Part 1. Microalgae in Food Product Development -- Chapter 1. Food and high value products from microalgae: market opportunities and challenges -- Chapter 2. Algae as a mainstream food ingredient: demand and supply perspective -- Chapter 3. Microalgae pigments: a source of natural food color -- Chapter 4. Algal biotechnology: a sustainable route for omega-3 fatty acids and carotenoids production -- Part 2. Microalgae in Health Product Development -- Chapter 5. Microalgae in human health and medicine -- Chapter 6. Astaxanthin production from microalgae -- Chapter 7. Microalgae nutraceuticals: the role of lutein in human health -- Part 3. Microalgae for Cosmetic Formulations -- Chapter 8. Algae and Aging -- Chapter 9. Extracts and bioactives from microalgae (sensu stricto): opportunities and challenges for a new generation of cosmetics -- Part 4. Other High Value Application -- Chapter 10. Microalgae as Vaccine Delivery System to Aquatic Organisms -- Chapter 11. Microalgal as a sustainable source for bioplastic -- Chapter 12. Microalgae as biofertillizer in modern agriculture -- Part 5. Biomass Production -- Chapter 13. Microalgae biomass production, drying and storage -- Chapter 14. Microalgal carbohydrate and proteins: synthesis, extraction, application and challenges -- Chapter 15. Pretreatment and lipid extraction from wet microalgae: Challenges, potential and application for industrial scale application.
    Abstract: "Microalgae Biotechnology for Food, Health and High Value Products” presents the latest technological innovations in microalgae production, market status of algal biomass-based products, and future prospects for microalgal applications. It provides stimulating overviews from different perspectives of application that demonstrate how rapidly the commercial production of microalgae-based food, health and high value products is advancing. It also addresses a range of open questions and challenges in this field. The book highlights the latest advances of interest to those already working in the field, while providing a comprehensive overview for those readers just beginning to learn about the promise of microalgae as a sustainable source of both specialty and commercial products. It offers a valuable asset for commercial algae producers, algae product developers, scientific researchers and students who are dedicated to the advancement of microalgae biotechnology for applications in health, diet, nutrition, cosmetics, biomaterials etc. .
    Type of Medium: Online Resource
    Pages: X, 483 p. 91 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811501692
    DDC: 660.6
    Language: English
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  • 16
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Nanotechnology. ; Cancer. ; Stem cells. ; Diseases. ; Biotechnology. ; Nanotechnology. ; Cancer Biology. ; Stem Cell Biology. ; Diseases.
    Description / Table of Contents: Chapter 1.Current Advances in Nanotechnology and Medicine -- Chapter 2. Least Explored Small Wonders: Nano-biotechnology -- Chapter 3. Modern Approaches in Nanomedicine for neuroAIDS and CNS drug delivery -- Chapter 4. Nanobiotechnology: Paving the way to personalized medicine -- Chapter 5. Nanomedicine in cancer stem cell therapy -- Chapter 6. Nanobiosensor: Current Trends and Applications -- Chapter 7. Transition Metal Oxide Nanoparticles: A New Horizon in Cancer Treatment -- Chapter 8. Nanomedicine meets microRNA expression and function in prostate cancer -- Chapter 9. Biomedical applications of Viral Nanoparticles in vaccine therapy -- Chapter 10. HIV: Biology to Nanomedicine -- Chapter 11. Current Advances in Phage Inspired Nanocarriers Based Therapy -- Chapter 12. Nanophytotherapeutic potential of Essential Oils against Candida infections -- Chapter 13. Molecular tests for the Diagnosis of Tuberculosis: Nanodiagnostics Approaches -- Chapter 14. Molecular Mechanisms of drug resistance in Mycobacterium tuberculosis: Role of nanoparticles against Multi-Drug Resistant tuberculosis (MDR-TB) -- Chapter 15. Nano-Mass spectrometry (nano-MS) based lipidomics -- Chapter 16. Techniques to understand Mycobacterial Lipids and use of Lipid Based Nanoformulations for Tuberculosis Management -- Chapter 17. Recent trends and challenges in Patches for cardiac tissue reengineering: role of Nanomaterials -- Chapter 18. Cyclic dinucleotides: Big roles of small molecules and its role in nanotechnology and medicine -- Chapter 19. Antibodies: Biology to Therapeutics and its role in nanomedicine -- Chapter 20. Nanotoxicology in Medicine -- Chapter 21. Antibody-targeted nanoparticles for cancer treatment -- Chapter 22. Nanoparticle mediated combined photothermal and photodynamic therapy -- Chapter 23. Nanotechnology based devices and its applications in medicine- Chapter 24. Opportunities in clinical translation and commercialization of nanomedicine. .
    Abstract: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology. .
    Type of Medium: Online Resource
    Pages: XX, 517 p. 90 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813298989
    DDC: 660.6
    Language: English
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    Keywords: Neurosciences. ; Animal culture. ; Veterinary medicine. ; Neuroscience. ; Animal Science. ; Veterinary Science.
    Description / Table of Contents: Rodents -- Carnivores -- Sheep and goats -- Swine -- Rabbits -- Bovines -- Non-human primates -- Humans -- Squirrels.
    Abstract: Modern neuroscience has presented new opportunities for exploring the molecular and neural mechanisms controlling specific social responses. This book reviews insights into the neural circuits underlying a particularly fascinating form of social interaction, parental behavior. This book presents a detailed review of maternal and paternal behavior of particular mammalian species. It offer neuroscientists a spectrum of specific mammals that can be used as experimental models to explore particular topics on the functions of the nervous system. It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild. It also discusses the implications of this research for human parental behavior. .
    Type of Medium: Online Resource
    Pages: V, 309 p. 45 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030977627
    Series Statement: Advances in Neurobiology, 27
    DDC: 612.8
    Language: English
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  • 18
    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Enzymology. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Enzymology. ; Nanotechnology.
    Description / Table of Contents: Immobilization: Then and Now -- Cell immobilization strategies for tissue engineering: Recent trends and future perspectives -- Strategies and advancement in growth factor immobilizable ECM for tissue engineering -- Prospects Of Cell Immobilization In Cancer Research And Immunotherapy -- Nano systems for repairing retinal degeneration -- Systemic drug delivery to the posterior segment of the eye: Overcoming blood-retinal barrier through smart drug design and nanotechnology -- The effects of irradiation with cold atmospheric-pressure plasma on cellular function -- Immobilization of biomolecules on plasma functionalized surfaces for biomedical applications -- A wide portray of Upconversion-nanoparticles: surface modification for bio-applications -- Advances in Amphiphilic Assemblies and its Immobilization in Room Temperature Supercooled Matrices. .
    Abstract: This book delves into the field of immobilizing biologically active and non-active molecules. It discusses the designing strategy of immobilization and the current state-of-the-art applications for advancing biomedical, agricultural, environmental and industrial practices. It focuses on aspects ranging from fundamental principles to current technological advances at multi-scale levels (macro, micro, and nano) which are suitable for cell, enzyme, and nano-catalyst based applications. Written by experts from across the globe, the contents deal with illustrated examples of molecular and cellular interactions with materials/scaffolds and discussions on factors that can affect the functionality and yield of the process. With its discussions on material science, design of delivery vehicles, separation science, additive manufacturing, agriculture and environmental science, this book will be a useful reference for researchers across multiple disciplines.
    Type of Medium: Online Resource
    Pages: X, 666 p. 143 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811579981
    Series Statement: Gels Horizons: From Science to Smart Materials,
    DDC: 660.6
    Language: English
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  • 19
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Geography. ; Environment. ; Power resources. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Regional Geography. ; Environmental Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Intro: Navigating Patagonian freshwaters- and this book -- 1: Are freshwaters wetlands? -- 2: Patagonian Andean lakes and climate change -- 3: Current state and recent changes of glaciers in the Patagonian Andes (35 °S to 55°S) -- 4: Biogeographical patterns of Patagonian freshwater microbiota -- 5: Extreme freshwater ecosystems from Patagonia: The Copahue-Agrio system -- 6: Mercury in aquatic systems of North Patagonia: sources, processes and trophic transfer -- 7: Diversity patterns across aquatic communities from peat bogs -- 8: Hydrologic Systems, water uses and emerging conflicts around freshwater availability in Patagonia -- 9: Land-use effects on aquatic ecosystems: An overview of environmental impacts and tools for ecological assessment -- 10: Patagonian wetlands: vertientes, vegas, mallines,turberas and lagunas -- 11: Fish and fisheries of the Patagonian steppe -- 12: Invasive species: The case of Didymosphenia geminata in Neuquén Province -- 13: Influence of the fish introduction in lakes of the arid Patagonia -- 14: Patagonian cultural limnology: knowledge and water management in Mapuche rural communities -- 15: Political Ecology, water valoration and Water Law deliberation in the Province of Tierra del Nacional de Tierra del Fuego -- 16: Freshwater systems in protected areas in Patagonia -- 17: Amphibians and waterbirds as bridges to conserve aquatic and terrestrial habitat in Patagonia -- 18: Integrated long term conservation strategies to recover the critically endangered Hooded Grebe (Podiceps gallardoi),an endemic waterbird of Austral Patagonia -- Conclusion: Reaching out for the UNDP Sustainable Development Goals in Patagonia.
    Abstract: The Freshwaters of Patagonia adopts a socioecological approach, in which experts from across Patagonia review recent, scientifically rigorous literature and data of their own, thus synthesizing the current knowledge directly relevant to understand the present state and future trends of icefields, freshwater and wetland ecosystems in this region. The book’s organization into three parts provides a studied and comprehensive view on the patterns and processes of the various ecosystems in Patagonia, and describes the sociological aspects of freshwater ecosystems, as well as characterizes the conservation of the freshwater and wetland ecosystems, in Patagonia. The chapters offer a broad, state-of-the-art overview of the current status of glaciers, freshwater and wetland ecosystems of this region, as well as studies of both local and large scale biodiversity patterns, and study cases of extreme and naturally polluted environments.The volume concludes with the current status of Patagonian freshwaters, and discusses the scientific, legal and administrative tools aimed at their sustainable management within the framework of the UNEP Sustainable Development Goals 2030 Agenda. A broad audience of students, scientists, engineers, environmental managers, and policy makers will be interested in this volume.
    Type of Medium: Online Resource
    Pages: XI, 541 p. 104 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031100277
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577.6
    Language: English
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  • 20
    Keywords: Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Abstract: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Type of Medium: Online Resource
    Pages: XIV, 256 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811943249
    DDC: 612.8
    Language: English
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  • 21
    Keywords: Neurosciences. ; Pain medicine. ; Neurology . ; Anesthesiology. ; Neuroscience. ; Pain Medicine. ; Neurology. ; Anesthesiology.
    Description / Table of Contents: Introduction to Acute, Chronic, and Episodic Pain -- Inflammation and Pain -- Animal Models of Pain and Anti-inflammatory Treatments -- Inflammatory Mediators, Nociceptors, and Their Interactions in Pain -- Immune and Glial Cells in Pain and Their Interactions with Nociceptive Neurons -- Sex Differences in Neuroimmune Interactions and Pain -- Neuroimmune Interactions in Itch -- Toll-like Receptors in Pain and Itch -- Immunotherapy and Pain -- Cell Therapy and Regenerative Pain Medicine - Preclinical Studies -- Cell-based Therapies in Pain Management -- Platelet-Rich Plasma and Autologous Conditioned Serum: Non-Cellular Biologic Therapies for Neuroimmune Modulation and the Treatment of Arthritis Pain -- Exercise and Diet in the Control of Inflammation and Pain -- Mechanism-Based Pain Therapies -- Neuromodulation in Pain Management -- What Patients Need to Know about Pain Therapy?.
    Abstract: As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be the turning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.
    Type of Medium: Online Resource
    Pages: X, 364 p. 45 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031292316
    DDC: 612.8
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Stem cells. ; Hematology. ; Regenerative medicine. ; Biotechnology. ; Stem Cell Biology. ; Hematology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Hematopoietic Stem Cells -- Mesenchymal Stem Cells -- Cord Blood Stem Cells -- Neural Stem Cells and Their Niche -- Skeletal Muscle Stem Cells -- Heart Muscle Tissue Engineering -- Induced Pluripotent Stem Cells -- Epigenetics of Somatic Cell Reprogramming -- Human Pluripotent Stem Cells and Neural Regeneration -- Dopaminergic Neuron-Related Stem Cells -- Liver Disease Modelling -- Organoids in Developmental Biology Research and Application -- Extracellular Vesicles -- Ethics in Stem Cell Applications.
    Abstract: This textbook describes the biology of different stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal cord blood, neural and muscle stem cells and also covers induced pluripotent stem cells and their applications. Further, it includes chapters on organoids, stem-cell based disease modelling, extracellular vesicles and one chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on lectures of the international master program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and participation of collaborating professors from Tongji University Shanghai, the book is a valuable source for students, postdocs and researchers, who would like to have introductory chapters on stem cell biology. It also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.
    Type of Medium: Online Resource
    Pages: XIV, 242 p. 37 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339234
    Series Statement: Learning Materials in Biosciences,
    DDC: 660.6
    Language: English
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  • 23
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Neurology . ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Neuroscience. ; Neurology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Description / Table of Contents: Sleep: Basic and Historical Aspects -- Sleep: Findings in Invertebrates and Lower Vertebrates -- Sleep: Evolutionary and Adaptive Changes in Birds and Mammals -- Sleep Loss: What Does it do to our Brain and Body -- Sleep: Neural Optimization as An Ultimate Function for Memory Consolidation -- Sleep: Disorders and Clinical Implications.
    Abstract: This book discusses the evolution of sleep and its possible function in the higher invertebrates and vertebrates, including humans. It describes the current concept of sleep and its functions, based on research on the mammalian system. To date, electrophysiological recordings of the brain waves, muscle activity, and eye movements are the only tools available for characterizing the sleep architecture in the majority of animals. In mammals and birds, only two distinct types of sleep are found – non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. Since the discovery of REM sleep, studies have been performed to understand the purpose of the two distinct sleep states in higher vertebrates (birds and mammals), and how REM sleep was evolved. The book summarizes the role of both REM and NREM sleep in the proper functioning of the brain and body. It covers various aspects of the role of sleep in important physiological processes, including memory consolidation, induction of synaptic plasticity, energy restoration, enhancing immune response, and maturation of neuronal circuitries during early life. Lastly, the book reviews the effects of chronic/acute sleep deprivation on memory consolidation, obesity, and the immune system in animal models and humans.
    Type of Medium: Online Resource
    Pages: XIV, 118 p. 30 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811571756
    DDC: 612.8
    Language: English
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  • 24
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Engineering design. ; Heart Surgery. ; Control engineering. ; Robotics. ; Automation. ; Biotechnology. ; Engineering Design. ; Cardiac Surgery. ; Control, Robotics, Automation.
    Description / Table of Contents: Chapter 1. Evolution of Artificial Heart Technology -- Chapter 2. Mechanisms of Heart Failure -- Chapter 3. Basis of Artificial Heart Technologies -- Chapter 4. Artificial Heart: Rotary Pump -- Chapter 5. Artificial Heart: Volume-Displacement Pump -- Chapter 6. Total Artificial Heart -- Chapter 7. Evaluation of Artificial Hearts -- Chapter 8. Selection of Artificial Heart Devices -- Chapter 9. Therapy Management of VADs -- Chapter 10. Challenges of Artificial Heart Devices -- Chapter 11. A Primary Study for Biocompatible Ventricular Assist Devices.
    Abstract: This book provides a comprehensive introduction to artificial hearts, summarizing the latest advances in basic technologies, design, evaluation, and management. Featuring 11 chapters, it discusses the origins of the artificial heart, the mechanisms of heart failure, and the principles of artificial heart technologies. Further, it offers an overview of rotary pumps and volume-displacement pumps, and addresses total artificial hearts. Lastly, the book covers evaluation, selection, therapy management, challenges, and the latest innovations. Given its scope, it is a valuable resource for researchers and technicians in the area of biomedical engineering, as well as surgeons.
    Type of Medium: Online Resource
    Pages: XV, 212 p. 37 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811543784
    DDC: 660.6
    Language: English
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  • 25
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Using electrical stimulation to explore and augment the functions of parietal-frontal cortical networks in primates -- 2. Multi-system benefits of epidural stimulation following spinal cord injury. 3. Neurostimulator for hippocampal memory prosthesis -- 4. Modern approaches to augmenting the brain functions -- 5. Brain machine interfaces within a critical perspective -- 6. An implantable wireless device for ECoG and cortical stimulation -- 7. BCI Performance improvement by special low jitter quasi-steady State VEP paradigm -- 8. Communication with Brain-Computer Interfaces in Medical Decision-Making -- 9. Neuroprotection and neurocognitive augmentation by photobiomodulation -- 10. Avoiding partial sleep - the way for augmentation of brain function -- 11. Augmentation of brain functions by nanotechnology -- 12. The impact of ageing and age-related comorbidities on stroke outcome in animal models and humans -- 13. Diagnostic markers of sub-clinical depression based on functional connectivity -- 14. Transcranial magnetic stimulation in autism spectrum disorders: modulating brainwave abnormalities and behaviors -- 15. Neurofeedback training with concurrent psychophysiological monitoring in children with autism spectrum disorder with comorbid attention deficit/hyperactivity disorder -- 16. Augmentation through interconnection: brain-nets and telemedicine -- 17. Cognitive augmentation via a brain/cloud interface -- 18. Augmentation of neuro-marketing by neural technology -- 19. Augmentation of nutrition by nanotechnology -- 20. Neural spintronics: noninvasive augmentation of brain functions -- 21. Does the power to suppress an action make us free? -- 22. Deep brain stimulation for Parkinson’s disease-future directions for enhancing motor function -- 23. Neuromodulation for gait -- 24. Augmentation and rehabilitation with active orthotic devices -- 25. Effects of rTMS on behavioral and electrocortical measures of error monitoring and correction function in children with autism spectrum disorder -- 26. Affective Virtual Reality Gaming for Autism -- 27. A machine learning approach to automatic phobia therapy with virtual reality -- 28. Vision augmentation by pharmacological enhancement of the visual experience -- 29. Cognitive enhancing substances and the developing brain: risks and benefits -- 30. Pharmacological approaches in the augmentation and recovery of brain function.
    Abstract: This book covers recent advances in the neural technology that produces enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the behavior and mind. Augmentation of brain function is achieved using brain implants for recordings, stimulation and drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. Existing methods of brain augmentation are evaluated, and new approaches are introduced. Brain circuitry and neuronal mechanisms that are candidates for augmentation are discussed. This volume provides novel insights into brain disorders, and new devices for brain repair. Information in this book is relevant to researchers in the field of neuroscience, engineering, and clinical practice. Philosophical and ethical implications of brain augmentation are also addressed. “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” – Ray Kurzweil "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " – Ioan Dumitrache “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” – György Buzsáki.
    Type of Medium: Online Resource
    Pages: XXII, 747 p. 189 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030545642
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 26
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomedical engineering. ; Radiology. ; Bioinformatics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Radiology. ; Computational and Systems Biology.
    Description / Table of Contents: Deep Learning in Medical Image Analysis -- Medical Image Synthesis via Deep Learning -- Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation -- Deep Learning Computer Aided Diagnosis for Breast Lesion in Digital Mammogram -- Decision support system for lung cancer using PET/CT and microscopic images -- Lesion Image Synthesis using DCGANs for Metastatic Liver Cancer Detection -- Retinopathy analysis based on deep convolution neural network -- Diagnosis of Glaucoma on retinal fundus images using deep learning: detection of nerve fiber layer defect and optic disc analysis -- Automatic segmentation of multiple organs on 3D CT images by using deep learning approaches -- Techniques and Applications in Skin OCT Analysis -- Deep Learning Technique for Musculoskeletal Analysis -- Index.
    Abstract: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
    Type of Medium: Online Resource
    Pages: VIII, 181 p. 131 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331283
    Series Statement: Advances in Experimental Medicine and Biology, 1213
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Plant physiology. ; Biotic communities. ; Population biology. ; Plant ecology. ; Freshwater and Marine Ecology. ; Plant Physiology. ; Community and Population Ecology. ; Plant Ecology.
    Description / Table of Contents: Antarctic Seaweeds: Biogeography, Adaptation and Ecosystem Services -- Diversity of Antarctic Seaweeds -- Biogeographic Processes Influencing Antarctic and Sub-Antarctic Seaweeds -- Detached Seaweeds as Important Dispersal Agents Across the Southern Ocean.-Biogeography of Antarctic Seaweeds Facing Climate Changes -- Comparative Phylogeography of Antarctic Seaweeds: Genetic Consequences of Historical Climatic Variations -- Underwater Light Environment of Antarctic Seaweeds -- Production and Biomass of Seaweeds in Newly Ice-Free Areas: Implications for Coastal Processes in a Changing Antarctic Environment -- Carbon Balance Under a Changing Light Environment -- Life History Strategies, Photosynthesis and Stress Tolerance in Propagules of Antarctic Seaweeds -- Form and Function in Antarctic Seaweeds: Photobiological Adaptations, Zonation Patterns and Ecosystem Feedbacks -- Successional Processes in Antarctic Benthic Algae -- Seaweed-Herbivore Interactions: Grazing as Biotic Filtering in Intertidal Antarctic Ecosystems -- Diversity and Functioning of Antarctic Seaweed Microbiomes -- Seaweeds in the Antarctic Marine Coastal Food Web -- Trophic Networks and Ecosystem Functioning -- Chemical Mediation of Antarctic Macroalgal-Grazer Interactions -- Brown Algal Phlorotannins: An Overview of their Functional Roles.
    Abstract: Seaweeds (macroalgae) represent the most striking living components in the Antarctic’s near-shore ecosystems, especially across the West Antarctic Peninsula and adjacent islands. Due to their abundance, their central roles as primary producers and foundation organisms, and as sources of diverse metabolically active products, seaweed assemblages are fundamental to biogeochemical cycles in Antarctic coastal systems. In recent years, the imminence of climate change and the direct impacts of human beings, which are affecting vast regions of the Antarctic, have highlighted the importance of seaweed processes in connection with biodiversity, adaptation and interactions in the benthic network. Various research groups have been actively involved in the investigation of these topics. Many of these research efforts have a long tradition, while some “newcomers” have also recently contributed important new approaches to the study of these organisms, benefiting polar science as a whole. This book provides an overview of recent advances and insights gleaned over the past several years. Focusing on a timely topic and extremely valuable resource, it assesses the challenges and outlines future directions in the study of Antarctic seaweeds.
    Type of Medium: Online Resource
    Pages: XIV, 397 p. 68 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030394486
    DDC: 577.6
    Language: English
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    Keywords: Biotechnology. ; Microbiology. ; Plant diseases. ; Microbial ecology. ; Biotechnology. ; Microbiology. ; Plant Pathology. ; Microbial Ecology.
    Description / Table of Contents: Bacterial Endophytes: Diversity, Functional Importance, and Potential for Manipulation -- Rhizosphere Carbon Turnover from Cradle to Grave: The Role of Microbe–Plant Interactions -- Root–Soil–Microbe Interactions Mediating Nutrient Fluxes in the Rhizosphere -- Diazotrophic Nitrogen Fixation in the Rhizosphere and Endosphere -- Root Microbiome Structure and Microbial Succession in the Rhizosphere -- Rhizosphere Legacy: Plant Root Interactions with the Soil and Its Biome -- Rhizosphere Microbiome and Soil-Borne Diseases -- Root Disease Impacts on Root-Rhizosphere Microbial Communities -- Newly Introduced or Modified Genes in Plants Potentially Modulate the Host Microbiome -- Rhizosphere Plant–Microbe Interactions Under Abiotic Stress -- Arbuscular Mycorrhizal Fungi Interactions in the Rhizosphere -- Microbial–Faunal Interactions in the Rhizosphere -- Inter-Organismal Signaling in the Rhizosphere -- Molecular Mechanisms of Plant–Microbe Interactions in the Rhizosphere as Targets for Improving Plant Productivity -- Inoculation Effects in the Rhizosphere: Diversity and Function.
    Abstract: This book presents a detailed discussion on the direct interactions of plants and microorganisms in the rhizosphere environment. It includes fifteen chapters, each focusing on a specific component of plant-microbe interactions, such as the influence of plants on the root microbiome, and the downstream effects of rhizosphere microbial dynamics on carbon and nutrient fluxes in the surroundings. As such, the book helps readers gain a better understanding of diversity above the ground, and its effect on the microbiome and its functionality.
    Type of Medium: Online Resource
    Pages: XVIII, 356 p. 36 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811561252
    Series Statement: Rhizosphere Biology,
    DDC: 660.6
    Language: English
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  • 29
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Entrepreneurship. ; New business enterprises. ; Public health. ; Biotechnology. ; Biomedical Research. ; Entrepreneurship. ; Public Health.
    Description / Table of Contents: Part I. What Is Wrong with Health? What Should the Future of Health Be? -- INNOVATION DESIGN for the FUTURE of HEALTH -- Health Innovations from an Innovators’ Perspective -- From SICKCARE to HEALTHCARE to HEALTH -- Future Look on Health: Opportunities -- Navigating Towards a Future of “One Health” -- Part II. Exponential Medicine + Technologies + Mindset -- Exponential Technologies for an Exponential Medicine -- Exponential Medicine: Challenges of Human Spaceflight Bringing Innovations for Earth—A Case Study -- Healthy Longevity -- The Science of Health Longevity -- Space Healthtech: Innovation Base for Longevity -- Part III. Future Health Value Propositions -- Healthcare the Melting Pot of Technology, Humanity, and Confusion -- Democratize Health Delivery -- Health Innovation Process: Definitions and Short Methodology Introductions -- Prevention, Prediction, Personalization, and Participation as Key Components in Future Health -- Digital Health Business Models: Transformation Is on the Horizon -- Value Propositions for Future Health Developments: Digital, Portable, Connected, Experience-Enhancing, Supportive, Patient-Centric, and Affordable -- (Digital) Patient Journey and Empowerment: Digital Twin -- Part IV. Innovation Methodology Basics -- Stanford Biodesign as Base: Empathy and Patient Centricity as the Main Driver -- Purpose Launchpad Methodology: Introduction -- Design Thinking for Innovations in Healthcare -- VPC to BMC to Exponential Canvas: Canvas Interconnectivity for Exponential Scaling -- Innovation Methodology I3 EME: Awareness for Biomedical Engineers -- Part V. Ethics + Health Innovation -- Integrating Ethical Considerations into Innovation Design -- Part VI. Health Innovation Design -- Case Studies Used Throughout the Book: Innovation Categories Explained -- Why Is Healthcare Different with Respect to Innovation and Entrepreneurial Activities? -- Purpose Launchpad Health (PLH) Methodology Introduction -- Part VII. Purpose Launchpad Health -- Purpose Launchpad Health: Exploration and Evaluation Phases—Actual Case Studies -- Part VIII. Health Leadership, Skills and other Methodologies -- Soft Skills Needed for Problem Understanding and Innovation Generation -- Leadership in Healthcare: A Novel Approach. Healthcare Executives’ Traits, Styles, and Approaches -- Future Skills Framework in Healthcare -- Porter’s Five Forces Analysis: Quo Vadis Immunotherapy Industry -- Part IX. Health Entrepreneurship -- Global Health Markets and Their Different Needs -- Patient: Health Relation and Digital Health Entrepreneurship -- Health Start-Up: Create Impact and be Investment Ready Intra- and Entre-Preneurs -- Regulatory Issues for Health Innovations -- Innovation Think Tank Frameworks for Resolving “The Innovator’s Dilemma” in Healthcare -- A Primer on Patents and IP for Health Innovations -- Successfully Implementing Ambidexterity in the Medical Industry -- Reverse Innovation: Circumvent Digital Health Transformation Issues -- Part X. Health Innovation Education and Incubation -- Health Innovation Design: “CAMPing” for the Unmet Clinical Need -- Health Technology Innovation Generation (HTIG) Lecture and Project Classes at AGH University -- Health Innovation Design at a University: INKA INNOLAB at Otto-von-Guericke-University -- Clinical Innovation at Acibadem Biodesign Center -- Example of a Needs-Driven Innovation Training Program: The BioMedical Design Novo Nordisk Foundation Fellowship Program -- Addressing the Healthcare Needs with Innovation Think Tank Global Infrastructure and its Methodology -- The Power of a Collaborative Ecosystem: Introducing the Edison™ Accelerator -- HealthTec Networks and Clusters (Global): Innovation Clusters in Medtech in Europe -- Leadership-Compass: “Networking and Synapting Empowered by Health Captains” -- Part XI. Purpose Launchpad Health: Toolset Templates and Principles -- PLH Templates and Principles.
    Abstract: This book highlights the reasons for an urgently needed revision of the current global healthcare setup, discusses the needed mindset for a future of health, and provides a comprehensive development toolset for disruption (and for the needed incremental innovations towards disruption). Today’s biomedical and health innovation related research in universities encourages activities that lead to incremental innovations with a relatively low risk of failure. The healthcare industry on the other hand provides tools and devices for established healthcare providers to improve the diagnosis and therapy/ treatment of the patients’ health problems. The patient is not in the center of healthcare provision however, and prevention and prediction are not core goals. The current health setup needs to be challenged and disrupted. Disruptions are coming from technologies or processes that lead to a significant (〉10x) reduction in cost or price/ performance and that also come with new business models. The need for change, effects of exponential technologies, and the needed shift to prevention and to homecare for health democratization and patient empowerment will be discussed in detail in the first parts of the book. The subsequent sections address several innovation methods with a focus on a novel meta methodology named Purpose Launchpad Health. This is followed by a comprehensive discussion on health entrepreneurship activities and needs. The final section of the book addresses how to train students to become entrepreneurial health innovators, presenting successful curricula and examples of health incubation and accelerator setups. All of the innovation tools presented and used in this book are summarized in the final chapter to help the reader get started planning an entrepreneurial venture. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments. Chapters are concise and enriched with key messages, learning objectives and real innovation examples to bridge theory and practice. This book aims to serve as a teaching base for health innovation design and to prepare for health-related entrepreneurial ventures. Readers with medical, biomedical, biotechnology, and health economics backgrounds - and anyone who wants to become a future oriented health innovator or who believes in disruptive approaches - will find this book a useful resource and teaching tool for developing validated products/ services and processes for the future of health.
    Type of Medium: Online Resource
    Pages: XXXIV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031081910
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Medicine Research. ; Biology Research. ; Psychology. ; Neuroscience. ; Biomedical Research. ; Behavioral Sciences and Psychology.
    Description / Table of Contents: Chapter 1: Neural Circuits Underlying Innate Fear -- Chapter 2: Neurobiology and Neural Circuits of Aggression -- Chapter 3: Neural Regulation of Feeding Behavior -- Chapter 4: Neural Circuits for Reward -- Chapter 5: Neuronal response and behavioral modulation in social interaction -- Chapter 6: Neural circuit mechanisms that underlie parental care -- Chapter 7: Spatial navigation -- Chapter 8: Neural circuits for sleep-wake regulation.
    Abstract: This book summarizes the latest research findings in the neurocircuitry of innate behaviors, covering major topics such as innate fear, aggression, feeding, reward, social interaction, parental care, spatial navigation, and sleep-wake regulation. For decades, humans have been fascinated by wild animals’ instincts, like the annual two-thousand-mile migration of the monarch butterfly in North American, and the “imprint” behavior of newborn birds. Since these instincts are always displayed in stereotypical patterns in most individuals of a given species, the neural circuits processing such behaviors must be genetically hard-wired in the brain. Recently, with the development of modern techniques, including optogenetics, retrograde and anterograde virus tracing, and in vivo calcium imaging, researchers have been able to determine and dissect the specific neural circuits for many innate behaviors by selectively manipulating well-defined cell types in the brain. This book discusses recent advances in the investigation of the neural-circuit mechanisms underlying innate behaviors.
    Type of Medium: Online Resource
    Pages: IX, 112 p. 13 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811570865
    Series Statement: Advances in Experimental Medicine and Biology, 1284
    DDC: 612.8
    Language: English
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    Keywords: Biotechnology. ; Food science. ; Biomaterials. ; Nanotechnology. ; Ceramic materials. ; Biotechnology. ; Food Science. ; Biomaterials. ; Nanotechnology. ; Ceramics.
    Description / Table of Contents: Carbon materials from various sources for composite materials -- Carbon Fibre Reinforced Polymer (CFRP) Composites: Machining Aspects and Opportunities for Manufacturing Industries -- Surface modification of graphene nanoplatelets (GNP) towards preparation of natural/synthetic rubber blend nanocomposites -- Mechanical properties of nanoclay composite materials -- Fireproof capability of rigid polyurethane foam based composite materials -- Structural behavior of composite materials in fire -- Natural resources based green composite materials -- Composite materials for wind turbine structure -- Electrochromic Smart Windows: An Energy-efficient Technology -- Graphitic Carbon Nitride/ Metal Oxides Nanocomposites and Their Applications in Engineering -- Application of Nanofiber-based Composites: Progressive Health Impact -- Polymer-based Nanocomposite: Recent Trends in Safety Assessments in biomedical applications -- Modern approach of hydroxyapatite based composites for biomedical applications -- Hybrid Composite in Orthopedic applications -- Polymer-based composite in biomedical applications -- Components of All-solid-state Ion-Selective Electrodes (AS-ISEs) -- Nanocellulose and Nanocellulose-based Composites for Food Applications -- Nanocomposite Materials in Food Packaging: Opportunities, Challenges and Safety Assessment -- Biodegradability and Composite Coatings: Past, Present and Future Prospects -- Nanocomposite Film for Food Packaging: Opening Doors to Future Applications -- Functional Chitosan-Based Composites for Potential Application in Food Industry -- Metal-insulator-metal as a biosensing platfrom .
    Abstract: Composite materials are formed when the combination of separate materials acquire new properties distinct from its components. They have a range of applications in fields such as mechanical and electrical engineering, food science and biomedicine and represent a fast-growing area of research. Composite Materials: Applications in Engineering, Biomedicine and Food Science provides an overview of current technologies and applications related to composite materials in these fields. Organized by discipline, the text encompasses a wide variety of composite materials, including polymer, ceramic, biomaterial, hydroxyapatite, nanofiber and green composites. Early chapters detail the enhanced mechanical, magnetic, dielectric properties of electrical and thermal conductive composite materials, which are essential in daily science. Subsequent chapters focus on filler or reinforcement materials, including carbon materials, hybrid materials and nanomaterials. Particular emphasis is placed on nanocomposite materials, as these have increasingly diverse field applications. Various manufacturing methods, such as the synthesis method and top-down/bottom-up manufacturing, are also discussed. Coverage of the recent progress, challenges and opportunities surrounding composite materials make this text a one-stop reference for engineers, scientists and researchers working in this exciting field.
    Type of Medium: Online Resource
    Pages: XI, 484 p. 213 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454890
    DDC: 660.6
    Language: English
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    Keywords: Neurosciences. ; Cognitive neuroscience. ; Psychobiology. ; Human behavior. ; Sociology. ; Neuroscience. ; Cognitive Neuroscience. ; Behavioral Neuroscience. ; Sociology.
    Description / Table of Contents: Molecular imaging of the human emotion circuit -- The neurocognitive mechanisms of unconscious emotional responses -- Social and Affective Neuroscience of Embodiment -- The neuroscience of beauty -- Mirror Neurons … in action: ERPs and neuroimaging evidence -- Sex differences in social cognition -- Development of morality and emotional processing -- Trust in Social Interaction: From Dyads to Civilizations -- The time has come to be mindwanderful: Mind wandering and the intuitive psychology mode -- Social Cognition development and socio affective dysfunction in childhood and adolescence -- Clinical neuroscience meets second-person neuropsychiatry -- EEG and ERPs in the study of Language and Social Knowledge -- fMRI and fNIRS methods for social brain studies: hyperscanning possibilities -- Modulating the Social and Affective Brain with transcranial stimulation techniques -- What our eyes can tell us about our social and affective brain? -- Facial EMG – Investigating the interplay of facial muscles and emotions.
    Abstract: This Open Access book presents the current state of the art knowledge on social and affective neuroscience based on empirical findings. This volume is divided into several sections first guiding the reader through important theoretical topics within affective neuroscience, social neuroscience and moral emotions, and clinical neuroscience. Each chapter addresses everyday social interactions and various aspects of social interactions from a different angle taking the reader on a diverse journey. The last section of the book is of methodological nature. Basic information is presented for the reader to learn about common methodologies used in neuroscience alongside advanced input to deepen the understanding and usability of these methods in social and affective neuroscience for more experienced readers.
    Type of Medium: Online Resource
    Pages: XXXIII, 302 p. 55 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031086519
    DDC: 612.8
    Language: English
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    Keywords: Biotechnology. ; Agriculture. ; Botany. ; Microbiology. ; Biology Technique. ; Biotechnology. ; Agriculture. ; Plant Science. ; Microbiology. ; Biological Techniques.
    Description / Table of Contents: 1.An Introduction to Beta Glucan and Beta Glucanases -- 2.Industrial Applications of Beta Glucanases -- 3.Microbial Sources of Beta Glucanase Enzymes -- 4.Role of Beta Glucanases in Animal Nutrition -- 5.Betaglucanse in Breweries -- 6. Exploitation of Actinobacteria for Beta Glucanolytic enzymes –Screening and Characterisation -- 7.Structural Characterisation of Beta Glucanase Genes from Actinobacteria -- 8.Application of Codon Optimization in Actinobacterial Beta Glucanases -- 9.Actinobacterial Beta Glucanases: Recombinant Expression of in E. coli -- 10.Purification and Properties of Recombinant Beta Glucanases Enzymes -- 11.Fungal Beta Glucanases -- 12.Industrial Production and Characterisation of Beta Glucanases -- 13.Protein Engineering of Beta Glucanase Enzymes -- 14.Biotechnological Avenues in Hybrid Beta Glucanase Enzyme Production.
    Abstract: This book offers an overview of the current knowledge on beta glucanase enzymes derived from actinobacterial source, their structure, functions and industrial applications. It summarizes the exploitation of actinomycetes, assay methods for beta glucanase screening, structural characterisation, genetic engineering, protein engineering, strategies for purification, characterisation and finally how to synthesize a hybrid enzyme of beta glucanases.Enzyme beta glucanases have considerable interest in industrial biotechnology owing to its distinct effect on the hydrolysis of insoluble beta glucan molecules and applications in particular industrial sectors such as food, feed and beverages industries. The beta glucanases are characterized extensively in microorganisms viz. bacteria, fungi and also in plants. A wide varieties of actinobacterial β- glucanases have exclusively active on β-glucan substrates and cleave the mixed linkage β-glucan chains at different points. This is significant for picking precise substrates for the assay of each type of enzymes within this enzyme groups. The well recognized specificity and mechanism of action within the enormous substrates allow to understand that most of them are varied from cellulases, excluding β-1,4-glucanases. The progress in genetic and protein engineering in actinobacterial beta glucanases improves the stability, activity and thermodynamic properties in relation with industrial relevance. This book will be useful for researchers and students engaged in industrial biotechnology, enzyme production, molecular biology, protein engineering and many more.
    Type of Medium: Online Resource
    Pages: X, 195 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811964664
    Series Statement: Interdisciplinary Biotechnological Advances,
    DDC: 660.6
    Language: English
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    Keywords: Freshwater ecology. ; Marine ecology. ; Reproduction. ; Physiology. ; Pollution. ; Freshwater and Marine Ecology. ; Reproductive Physiology. ; Pollution.
    Description / Table of Contents: 1. Pesticide and xenobiotic metabolism in aquatic organisms -- 2. Endocrine disrupting activity of xenobiotics in aquatic animals -- 3. Water contamination through xenobiotics and their toxic effects on aquatic animals -- 4. Cypermethrin induced reproductive toxicity in zebrafish: biochemical and molecular perspective -- 5. Impact of Pesticides Application on Aquatic Environments And Biodiversity -- 6. Impact of microplastics on reproductive and physiological aspects of aquatic inhabitants -- 7. The Impact of Xenobiotics in Development & Reproduction of fresh water Fishes -- 8. Mixtures and Reproduction in Aquatic Organisms – benefits and challenges -- 9. Phytoestrogens as Endocrine-Disrupting Agents In Aquaculture -- 10. A Proteomic Approach to Studying the Effects of Xenobiotics on Aquatic Living Organisms -- 11. Role of Cytochrome P450 in xenobiotic metabolism in fishes -- 12. Pharmacokinetic-Pharmacodynamic modelling of Xenobiotics: Fate and effect in Aquatic Animals -- 13. Occurrence of xenoestrogen alkylphenols (Octylphenols and Nonylphenol), and its impact on the aquatic ecosystem -- 14. Xenobiotics' effect on fish reproduction and development -- 15. Scientometric analysis of ecotoxicological investigations of xenobiotics in aquatic animals -- 16. Toxic effects of nanomaterials on aquatic animals and their future prospective -- 17. Microplastic Contamination in Aquatic organisms: An Ecotoxicological perspective -- 18. Effect of xenobiotics and their degradation in aquatic life -- 19. Transcriptome analysis of aquatic species exposed to endocrine disruptors -- 20. Fundamentals of genotoxicity and antiparasitic drugs associated with genotoxicity in fish -- 21. Endocrine disrupting compounds (EDCs) as emerging aquatic contaminants: Emphasis on Reproduction and Development.
    Abstract: This book summarizes the latest understanding of the impact of xenobiotics on the developmental and reproductive processes of aquatic animals, particularly nektonic forms, which comprise an important group of aquatic ecosystems. Aquaculture is quickly becoming the largest contributor of fish protein for human consumption. As the aquaculture business expands, farmed fish will be exposed to more environmental toxins, necessitating the use of chemical therapeutic drugs for fish. This book brings together experts on the regulation of environmental toxins and food chemicals from around the world, as well as researchers looking into the metabolism and disposal of foreign chemicals (xenobiotics) in fish species. The impact of xenobiotics on reproductive and developmental biology of all living forms has become of prime importance at the current time. As the effect of these xenobiotics on aquatic animals is an emerging area for research and development, several groups across the world are working on these aspects, targeting different groups of fishes in both marine and freshwater ecosystems. This collective work highlights several key and updated recent aspects of different types of xenobiotics entering aquatic ecosystems, impacts of these agents on reproductive physiology, developmental biology, breeding biology, hormonal imbalance, aquatic ecology, and pollution on the aquatic ecosystem. The unique aggregation of different types of stressors to aquatic animals under a single volume will be a useful reference for readers, including scientists, teachers, students, researchers and policymakers and those involved in aquaculture and environment conservation.
    Type of Medium: Online Resource
    Pages: XXIX, 427 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819912148
    DDC: 577.6
    Language: English
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  • 35
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomaterials. ; Mathematical models. ; Dentistry. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Mathematical Modeling and Industrial Mathematics. ; Dentistry. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1 - Systematic Errors in Longitudinal Measurements -- Chapter 2 - Endodontic Treatment and Vertical Root Fracture -- Chapter 3 - Debonding of Resin Composite Restorations -- Chapter 4 - Attenuation of Curing Light through Resin Composite Restorations -- Chapter 5 - Release of Ions or Molecules from Dental Restorations -- Chapter 6 - Heat Generated from Dental Resin Composites during Curing -- Chapter 7 - Mechanical Failure of Dental Restorations – The Weakest-Link Theory -- Chapter 8 - Stability of Dental Implants -- Chapter 9 - Kinetics of Photo-polymerization -- Index.
    Abstract: This book presents a mechanistic approach—mathematical modeling—for carrying out dental materials research. This approach allows researchers to go beyond the null hypothesis and obtain a solution that is more general and therefore predictive for conditions other than those considered in a study. Hence it can be used either on its own or to complement the commonly used statistical approach. Through a series of practical problems with wide-ranging application, the reader will be guided on: How to construct a mathematical model for the behavior of dental materials by making informed assumptions of the physical, chemical, or mechanical situation How to simplify the model by making suitable simplifications How to calibrate the model by calculating the values of key parameters using experimental results How to refine the model when there are discrepancies between predictions and experiments Only elementary calculus is required to follow the examples and all the problems can be solved by using MS Excel© spreadsheets. This is an ideal book for dental materials researchers without a strong mathematical background who are interested in applying a more mechanistic approach to their research to give deeper insight into the problem at hand. Advance praise for Mathematical Models for Dental Materials Research: “This is a nice addition for research students on how to conduct their work and how to manage data analysis. It brings together a number of important aspects of dental materials investigations which has been missing in the literature. The practical examples make it much easier to understand.” – Michael F. Burrow, Clinical Professor in Prosthodontics, The University of Hong Kong “The great strengths of this volume are the real world examples of dental materials research in the successive chapters. In turn, this is an outcome of the outstanding expertise of both authors. I warmly recommend this book to the dental biomaterials community worldwide.” – David C. Watts, Professor of Biomaterials Science, University of Manchester, UK.
    Type of Medium: Online Resource
    Pages: XIV, 77 p. 41 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378493
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Environment. ; Renewable energy sources. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Biotechnology. ; Environmental Sciences. ; Renewable Energy. ; Fossil Fuel.
    Description / Table of Contents: Chapter 1. Growth of Biofuels Sector: Opportunities, Challenges and Outlook -- Chapter 2. Bioconversion of Agro-Industrial Residues to Second-Generation Bioethanol -- Chapter 3. Catalytic Transformation of Ethanol to Industrially Relevant Fine Chemicals -- Chapter 4. Selective Bioethanol Conversion to Chemicals and Fuels via Advanced Catalytic Approaches -- Chapter 5. A Spotlight on Butanol and Propanol as Next-Generation Synthetic Fuels -- Chapter 6. Technological Advancements in the Production and Application of Biomethanol -- Chapter 7. Biorefinery Approaches for Production of Fuels and Chemicals from Lignocellulosic and Algal Feedstocks -- Chapter 8. Conversion of Rice Husk and Nutshells into Gaseous, Liquid and Solid Biofuels -- Chapter 9. A Review of Thermochemical and Biochemical Conversion of Miscanthus to Biofuels -- Chapter 10. Process Improvements and Techno-Economic Feasibility of Hydrothermal Liquefaction and Pyrolysis of Biomass for Bio-Crude Oil Production -- Chapter 11. Biocrude Oil Production via Hydrothermal Liquefaction of Algae and Upgradation Techniques to Liquid Transportation Fuels -- Chapter 12. Co-pyrolysis of Lignocellulosic Biomass and Polymeric Wastes for Liquid Oil Production -- Chapter 13. Conversion of Waste Biomass to Bio-oils and Upgradation by Hydrothermal Liquefaction, Gasification and Hydrodeoxygenation -- Chapter 14. Upgrading of Bio-oil from Biomass Pyrolysis: Current Status and Future Development -- Chapter 15. Heterogeneous catalysis in Hydroxymethylfurfural Conversion to Fuels and Chemicals -- Chapter 16. Conversion of Glycerol to Value-added Products -- Chapter 17. Recent Advances in Steam Reforming of Glycerol for Syngas Production -- Chapter 18. Conversion of Biogas to Syngas via Catalytic Carbon Dioxide Reforming Reaction: An Overview of Thermodynamic Aspects, Catalytic Design and Reaction Kinetics -- Chapter 19. Opportunities of Biodiesel Compatibility as a Modern Combustion Engine Fuel -- Chapter 20. Current Advancements in Microbial Fuel Cell Technologies.
    Abstract: This book summarizes recent advances in the processing of waste biomass resources to produce biofuels and biochemicals. Worldwide interest in clean energy sources, environmental protection, and mitigating global warming is rapidly gaining momentum and spurring on the search for alternative energy sources, especially for the transportation and industrial sectors. This book reviews the opportunities presented by low-cost organic waste materials, discussing their suitability for alternative fuel and fine chemical production, physicochemical characterization, conversion technologies, feedstock and fuel chemistry, refining technologies, fuel upgrading, residue management, and the circular economy. In addition, it explores applied aspects of biomass conversion by highlighting several significant thermochemical, hydrothermal and biological technologies. In summary, the book offers comprehensive and representative descriptions of key fuel processing technologies, energy conversion and management, waste valorization, eco-friendly waste remediation, biomass supply chain, lifecycle assessment, techno-economic analysis and the circular bioeconomy.
    Type of Medium: Online Resource
    Pages: XVIII, 494 p. 111 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811518041
    DDC: 660.6
    Language: English
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  • 37
    Keywords: Neurosciences. ; Neurology . ; Pharmacology. ; Neuroscience. ; Neurology. ; Pharmacology.
    Description / Table of Contents: Chapter 1: Why study Drug Resistant Epilepsy? -- Chapter 2: Pharmacoresistance in Epilepsy -- Chapter 3: Experimental models for the study of drug-resistant epilepsy -- Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy -- Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy -- Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level? -- Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy -- Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy -- Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy -- Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy -- Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP -- Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance -- Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance -- Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration -- Chapter 15: Application of proteomics in the study of molecular markers in epilepsy -- Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies -- Chapter 17: Genes involved in pharmacoresistant epilepsy -- Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders -- Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery -- Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses -- Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility -- Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy -- Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy -- Chapter 24: Vagus Nerve Stimulation for Intractable Seizures -- Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy -- Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.
    Abstract: This new edition of Pharmacoresistance in Epilepsy addresses all issues relating to drug-resistance in epilepsy, including studies in patients as well in experimental models and presents the basis for an understanding of recent developments in the pathogenesis and treatment of this condition. Important issues associated with drug-resistant epilepsy are reviewed and updated, such as abnormalities in inhibitory mechanisms, neurotoxicity and changes the immune system associated with this disorder, and the development of drug-resistance as consequence of chronic exposure to antiseizure-medications. Considering that a major obstacle is that epilepsy associated with drug-resistance cannot be controlled with the traditional antiseizure medications, specific chapters describe therapeutic strategies to prevent or reduce the progression of the disease with complementary medical therapies, such as transcranial focal stimulation to promote neuroprotection. Pharmacoresistance in Epilepsy is a valuable resource for anyone working in the field, whether studying epilepsy in the lab or treating it in an office.
    Type of Medium: Online Resource
    Pages: XV, 596 p. 84 illus., 79 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031365263
    DDC: 612.8
    Language: English
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  • 38
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurology . ; Developmental neurobiology. ; Neuroscience. ; Neurology. ; Development of the Nervous System.
    Description / Table of Contents: The development of the cerebellum: from the beginnings -- Part I: Responsibilities and liabilities -- Chapter2. The embryology and anatomy of the cerebellum -- Chapter 3. Cellular and genetic programs underlying cerebellum development -- Chapter 4. Early Purkinje Cell Development and the Origins of Cerebellar Patterning. - Chapter 5. Development of the Fish Cerebellum. -Chapter 6. Cerebellar developmental disorders and cerebellar nuclei -- Chapter 7. Motor circuit abnormalities during cerebellar development -- Chapter8. Developmental disorders of the cerebellum and neurotrophic factors -- Chapter9. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development -- Chapter10. The ubiquitin proteasome system and cerebellar developmental disease -- Chapter11. Epigenetics and Cerebellar Neurodevelopmental Disorders -- Chapter12.. Hormonal regulation of cerebellar development and its disorders -- Chapter13. Infections of the Cerebellum -- Chapter14. Neuroimmune mechanisms of cerebellar development and its developmental disorders -- Chapter15. Teratogenic influences on cerebellar development -- Chapter16. Primary pediatric brain tumors of the posterior fossa -- Chapter17. Primary pediatric brain tumors of the posterior fossa -- Chapter18. Can cerebellar neurodevelopmental disorders affect behavioral disorders or vice versa -- Chapter19. Neurodevelopmental disorders of the cerebellum: autism spectrum disorder -- Chapter20. Congenital cerebellar disease -- Chapter21. Clinical features, assessment, and management of patients with developmental and other cerebellar disorders -- Chapter22. Epidemiology of cerebellar disorders -- Chapter23. Cerebellar transplantation: a potential model to study repair and development of neurons and circuits in the cerebellum. - Chapter 24. Non-coding RNAs and cerebellar development. - Chapter 25. Defining the Cerebellar Cytoarchitecture Using MRI. .
    Abstract: This updated reference covers diverse aspects of cerebellar development from a full range of viewpoints, including the epidemiology of cerebellar genetic disorders, developmental anatomy, cell biology, genetics, epigenetics, infectious diseases, and mechanisms involved in the regulation of cell fate, while also focusing on information that is relevant to clinicians caring for patients with cerebellar disorders. The chapters are written by experts in the field of cerebellar development, and the chapters cover diseases related to the cerebellum, along with their epidemiology, clinical features, assessment, and management. In addition to updating the content to cover the significant developments in the field since the first edition, the second edition will include new chapters on Non-Coding RNAs and Cerebellar Development, Development of the Fish Cerebellum, the Role of nNOS/NO on Cerebellar Development in Health and Disease, and rehabilitation in cerebellar ataxia. The effect of the COVID-19 on the cerebellum has been included in related chapters. Development of the Cerebellum from Molecular Aspects to Diseases, 2nd edition, is designed to be valuable reference for both neuroscientists and clinicians.
    Type of Medium: Online Resource
    Pages: IX, 639 p. 116 illus., 88 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031231049
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 39
    Keywords: Neurosciences. ; Neurology . ; Neuroscience. ; Neurology.
    Description / Table of Contents: PART 1: WAKEFULNESS -- Chapter 1. Exploring Oscillations in Expert Sensorimotor Anticipation: the Tennis Return of Serve -- Chapter 2. Theta Rhythm in Hippocampus and Cognition -- Chapter 3. Oscillations and Synchrony in Attention -- Christian Keitel, Gregor Thut, and Joachim Gross -- Chapter 4. Pathological High-Frequency Oscillations in Mesial Temporal Lobe Epilepsy -- PART TWO: SLEEP -- Chapter 5. Cellular Mechanisms of Thalamocortical Oscillations in the Sleeping Brain -- Chapter 6. Neuroimaging of Brain Oscillations During Human Sleep -- Chapter 7. A Role for Neuronal Oscillations of Sleep in Memory and Cognition -- Chapter 8. Sleep Oscillations and Aging -- Chapter 9. Sleep Oscillations and Psychiatric Disorders.
    Abstract: This edited volume reviews recent findings that highlight the mechanisms and functions of the neuronal oscillations that structure brain activity across the sleep-wake cycle. An increasing number of studies conducted in humans and animals use a variety of techniques, ranging from intracellular recording to functional neuroimaging, that provide important insight into the mechanisms and functional properties of these brain rhythms. This book explores how the studies of these rhythms are fundamental not only for basic neuroscience, but also for clinical neuroscience. At the basic science level, neuronal oscillations shape the interactions between different areas of the brain and profoundly impact neural responses to the environment, thereby mediating the processing of information in the brain. At the clinical level, brain oscillations are affected in numerous neurological conditions and might provide useful biomarkers that inform about patients’ evolution and vulnerability. During sleep, these brain rhythms could provide functional support to internal states that govern the basic maintenance of local circuit and systemic interactions. During wake, the rhythmicity of cortical and subcortical circuits have been linked with sensory processing, cognitive operations, and preparation for action.This volume attempts to link together these sleep and wake functional roles at the level of neuroimaging and electroencephalographic measures, local field potentials, and even at the cellular level. .
    Type of Medium: Online Resource
    Pages: XXI, 277 p. 40 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9781071606537
    DDC: 612.8
    Language: English
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  • 40
    Keywords: Biotechnology. ; Sustainability. ; Biomaterials. ; Biotechnology. ; Sustainability. ; Biomaterials.
    Description / Table of Contents: Chapter 1_Biomass to liquid fuels: Recent trends in techniques in catalytic conversions -- Chapter 2_Towards sustainable production of hydrogen and biogas from biomass residues -- Chapter 3_ Biorefinery for biofuel production: A Case Study -- Chapter 4_Techno economic analysis and profitability analysis of biofuel production -- Chapter 5_Life cycle analysis and environmnetal impact of bio fuel production -- Chapter 6_Valorization of non lignocellulosic bio waste for BioChemicals -- Chapter 7_State of art technologies for production of biochemicals from biomass -- Chapter 8_Nutraceuticals functional foods and specialty chemicals -- Chapter 9_Technoeconomical analysis of BioChemical production: A Case study -- Chapter 10_Life cycle assessment and sustainability for production of pectin -- Chapter 11_Production of biofertilizers from agro residue: sustainability issues and challenges -- Chapter 12_Utilization of activated carbon obtained from biomass in waste water treatment -- Chapter 13_Sustanability and life cycle assessment of nano-materials from biomass -- Chapter 14_Biorefinery approach for production of enzymes from fruit peel waste -- Chapter 15_Production of Biomaterials: A Case study.
    Abstract: This book discusses recent trends and concepts in the field of biorefinery. It discusses optimal and economic strategies for converting biomass to value-added products to maximize profits with minimal environmental impact with a sustainability approach. The chapters of the book are focused on the current technologies, techno-economical aspects, life cycle assessment, and case studies. The book is divided into three sections; the first section presents strategies for the production of biofuels like bioethanol, biomethane, biohydrogen, bio-oil, gasification, etc., from the biomass in a sustainable way. The second sections review the extraction of bioactive chemicals, phenolic antioxidants, enzymes, and carboxylic acid from the biomass residue. The last section examines the utilization of biomass for the production of bioactive materials, including biofertilizers, bioadsorbents, activated carbon, nano-materials, and pigments. This book explores the relation between biofuels and the sustainable development goals (SDGs) 7.
    Type of Medium: Online Resource
    Pages: XII, 409 p. 56 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811974816
    DDC: 660.6
    Language: English
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  • 41
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Neurosciences. ; Medical care. ; Neurology . ; Biomedical engineering. ; Biotechnology. ; Neuroscience. ; Health Care. ; Neurology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1: Application of reinforcement and deep learning techniques in brain machine interfaces -- Chapter 2: Specific muscle activation patterns in athletic and orthopedic populations: considerations for using surface electromyography in assistive and biofeedback device applications -- Chapter 3: Kineto-dynamic modeling of human upper limb for robotic manipulators and assistive applications -- Chapter 4: Learning from the human hand: force control and perception using a soft-synergy prosthetic hand and non-invasive haptic feedback -- Chapter 5: Design of a soft glove-based robotic hand exoskeleton with embedded synergies -- Chapter 6: Model predictive control based knee actuator allocation during a standing-up motion with a powered exoskeleton and functional electrical stimulation -- Chapter 7: Deep brain stimulation for gait and postural disturbances in Parkinson’s disease -- Chapter 8: Cognitive and physiological intent for the adaptation of motor prostheses -- Index.
    Abstract: This book provides a comprehensive review of recent developments in the field of motor neuroprosthetics and brain-machine interfaces. Chapters in this book are provided by leading experts in the field and include topics such as the design and control of multidimensional prosthetics and exoskeletons, deep brain stimulation, functional electrical stimulation, deep learning for brain machine interfaces, biofeedback, and cognitive intent for adaptation of motor prostheses. This book is a great resource for undergraduate and graduate students, researchers, engineers from related disciplines, entrepreneurs, and anyone interested in the latest progress in the field of motor neuroprostheses.
    Type of Medium: Online Resource
    Pages: XII, 162 p. 57 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030387402
    DDC: 660.6
    Language: English
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  • 42
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Semiotics. ; Communication. ; Ethnology. ; Social sciences. ; Humanities. ; Behavioral Neuroscience. ; Semiotics. ; Media and Communication. ; Ethnography. ; Humanities and Social Sciences.
    Description / Table of Contents: Chapter 1: Bateson, Cybernetics, and Nonverbal Communication -- Chapter 2: Analog and Digital Communication, and Similar Contrasts -- Chapter3: The Slash Mark: Gregory Bateson’s Cybernetic Semiotic -- Chapter4: Intention Movements and Peacemaking Ceremonies -- Chapter5: Relational Communication in Octopus -- Chapter6: Cuban Missile Crisis -- Chapter7: False and True Lessons from the Cuban Missile Crisis -- Chapter8: A Level too Low.
    Abstract: This book develops Gregory Bateson’s ideas regarding “communication about relationship” in animals and human beings, and even nations. It bases itself on Bateson’s theory of relational communication, as he described it in the zoosemiotics of octopus, mammals, birds, and human beings. This theory includes, for example, the roles of metaphor, play, analog and digital communication, metacommunication, and Laws of Form. It is organized around a letter from Gregory Bateson to his fellow cybernetic thinker Warren McCulloch at the time of the Cuban Missile Crisis. In this letter Bateson argued that what we would today call zoosemiotics, including Bateson’s own (previously unpublished) octopus research, should be made a basis for understanding the relationship between the two blocs of the Cold War. Accordingly the book shows how Bateson understood interactive processes in the biosemiotics of conflict and peacemaking, which are analyzed using examples from recent animal studies, from primate studies, and from cultural anthropology. The Missile Crisis itself is described in terms of Bateson’s critique of game theory which he felt should be modified by an understanding of the zoosemiotics of relational communication. The book also includes a previously unpublished piece by Gregory Bateson on wolf behavior and metaphor/ abduction.
    Type of Medium: Online Resource
    Pages: XIX, 189 p. 7 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030521011
    Series Statement: Biosemiotics, 20
    DDC: 612.8
    Language: English
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  • 43
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Microbiology. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Industrial microbiology. ; Biotechnology. ; Microbiology. ; Medical Microbiology. ; Biomedical Research. ; Industrial Microbiology.
    Description / Table of Contents: Chapter 1. The sugar-nucleotide providing enzyme, opportunity and future in the antibody and peptide medicine area -- Chapter 2. The Next Generation of Microalgae-Based Products -- Chapter 3. Advanced techniques for enzymatic and chemical bleaching for pulp and paper industries -- Chapter 4. Commercial bioinoculant development: Techniques and challenges -- Chapter 5. Protein nanostructures with purpose-designed properties in biotechnology and medicine -- Chapter 6. Recent advances in biosynthetic production of Biopigments from microlagae -- Chapter 7. Revealing of the features of the oxidative enzyme production by white-rot basidiomycetes during fermentation of plant raw materials -- Chapter 8. Endophytic bacterial applications in phytoremediation of organic pollutants and toxic metals -- Chapter 9. Biotechnological interventions for Arbuscular Mycorrhizal Fungi (AMF) based biofertilizer: technological perspectives -- Chapter 10. Probiotics and prebiotics: Techniques used and its relevance -- Chapter 11. Techniques of Evaluation of the chemical and microbiological quality of the coastal environment -- Chapter 12. Enzyme engineering techniques for biotechnological applications.
    Abstract: This book compiles the latest research on the multifarious roles of microbial enzymes, and provides an overview of microbial enzymes and biotechnologies. It discusses the use of microbial enzymes in innovative areas like nanomedicine and synthetic biotechnology, as well as the use of starch digesting enzymes and bioactive proteins as biotherapeutics, all of which have applications in modern drug discovery processes. The book also examines the concept of microbial biotransformation and protein engineering, and covers topics such as the immobilization of therapeutic enzymes, bioengineering of enzymes for bioactive compounds, the production of hydrolytic and oxidative enzymes from plant raw materials, and prebiotics and probiotics. Given its multidisciplinary scope, this book will appeal to researchers and industry experts in the fields of microbiology, biotechnology and molecular medicine.
    Type of Medium: Online Resource
    Pages: XIV, 249 p. 83 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811568954
    DDC: 660.6
    Language: English
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  • 44
    Keywords: Biotechnology. ; Food science. ; Biotechnology. ; Food Science.
    Description / Table of Contents: Section A: Food Processing and Technology Innovations -- Chapter 1. Food Innovation and Sustainable Development: A Bio-economics Perception -- Chapter 2. Fermented pearl millet weaning food: an innovation of food technology and application in food processing and management -- Chapter 3. Processing methodologies for few crops in India: Arecanut, betelvine, cashew, cocoa and oil palm -- Chapter 4. Omega 3 fatty acid from plant sources and its application in Food Technology -- Chapter 5. Taizzy Smoked Cheese -- Chapter 6. Plant-Based Milk Substitutes: A novel non-dairy source -- Chapter 7. Makhana: Dry Food and a potential aquatic cash crop.-Chapter 8. An insight over creal β glucan as functional ingredient -- Section B: Food and Industrial Microbiology -- Chapter 9. Rediscovering Medicinal activity and Food Significance of Shogaol (4, 6, 8, 10 and 12): A comprehensive view.-Chapter 10. Exopolysaccarides derived from Beneficial Microorganisms: Antimicrobial, Food and Health benefits.-Chapter 11. Biofilm threat for food and industrial microbiology: An approach for its Elimination Using Herbal food components -- Chapter 12. Cyanobacterial exopolysaccharides as natural source for food packaging application.-Chapter 13. Microbial laccase production and its industrial applications -- Chapter 14. Lichens are the next promising candidates for active compounds.-Chapter 15. Microbial Production and Applications of L-lysine.-Chapter 16. Pomegranate peel: Nutritional values and its emerging potential for use in food systems -- Section C: Food Technology and Environmental Biotechnology -- Chapter 17. Bio-fertilizer from Trichoderma: Boom for Agriculture Production and Management of soil-borne and root-borne plant pathogens -- Chapter 18. Influence of heavy metal on food security: Recent advances -- Chapter 19. Utilization and management of agro and food processing waste -- Chapter 20. Nexus between Climate Change and Food Innovation Technology: Recent Advances -- Chapter 21. Antibiotic Residues in Food: A Global Concern for Human Health -- Chapter 22. Effects of toxicant from pesticides on food security: Current developments -- Chapter 23. Cr pollution, its impact and mitigation -- Chapter 24. Biosorption: A Novel Biotechnological Application For Removal of Hazardous Pollutants -- Section D: Agriculture, Food, Nutrition and Health Security -- Chapter 25. Emerging dichlorvos-based air freshener pertube kidney function in male albino rats -- Chapter 26. Consumption of green chilli& its nutritious effect on human health -- Chapter 27. Synthesis, characterization and evaluation of toxicity of melatonin loaded poly (D, L-lactic acid) Nano-Particles (Mel-PLA-Nano-Particles) and its putative use in osteoporosis -- Chapter 28. Nutritional Physiology -- Chapter 29. Caffeine: Nutraceutical and Health Benefit of Caffeine Containing Commodities and Products -- Chapter 30. Nutraceuticals potential of major edible oilseeds of India -- Chapter 31. Elimination of fungal Leaf Mosaic disease of Bottle Gourd (LagenariaSiceraria ) using Fungo-Phage Therapy: A possible approach for food security with plant protection -- Chapter 32. β- sitosterol - predominant phytosterol of therapeutic potential -- Chapter 33. Odonto-nutraceuticals: Phytochemicals for Oral Health Care -- Chapter 34. Pharmacological potential of thymol -- Chapter 35. TRIKATU- transforming food into medicines -- Chapter 36. Dietary factors associated with cancer. .
    Abstract: This book gathers a collection of essays that describe recent innovations in food technology including food processing, packaging, food safety, and novel ingredients. By 2050, the world will face the challenge of having to feed an estimated 9 billion people. In order to meet that challenge, innovations in food research are of the utmost importance. The book is divided into four sections, each of which explores an important aspect like food processing, food microbiology, and nutritional security. Written by respected scholars in the field, the respective chapters discuss a range of new and enhanced food materials, as well as processing innovations to extend shelf life and reduce toxic effects. The book also addresses the health potential of various nutraceuticals, bio-absorption of metals and their positive impacts on living systems, as well as methods for reducing food wastage, preventing the loss of nutritive value, and preserving or enhancing palatability. Given its scope, the book will be highly interesting for food scientists, both in academia and the food industry. It will also benefit advanced graduate students and senior researchers.
    Type of Medium: Online Resource
    Pages: XXIV, 522 p. 95 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811561214
    DDC: 660.6
    Language: English
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  • 45
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Endocrine glands. ; Neuroscience. ; Endocrine System.
    Description / Table of Contents: Photoperiodism and Circannual Timing: Introduction and Historical Perspective.-The Pars Tuberalis and Seasonal Timing -- Tanycytes and Their Pivotal Role in Seasonal Physiological Adaptations -- Epigenetic Mechanisms in Developmental and Seasonal Programs -- Plasticity of Neuroendocrine Mechanisms Regulating Seasonal Reproduction in Sheep -- Clocks and Calendrars in Birds -- Calendar Timing in Teleost Fish -- Action of Light on the Neuroendocrine Axis -- Seasons, Clocks, and Mood -- Photoperiodic Modulation of Clock Gene Expression in the SCN -- Circadian Timekeeping in the Suprachiasmatic Nucleus: Genes, Neurotransmitters, Neurons and Astrocytes. .
    Abstract: This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of “clock“ gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. .
    Type of Medium: Online Resource
    Pages: XII, 244 p. 64 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030556433
    Series Statement: Masterclass in Neuroendocrinology, 10
    DDC: 612.8
    Language: English
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  • 46
    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Opportunities for real time monitoring of biomolecules using FRET-based nanosensors -- Chapter 2. Current status of nanosensors in biological sciences -- Chapter 3. Biosensor: An Approach Towards a Sustainable Environment -- Chapter 4. Nanobiosensor in health sector: The milestones achieved and future prospects -- Chapter 5. Nanosensors based on DNA as an emerging technology for the detection of disease -- Chapter 6. Genetically Encoded Nanobiosensors for Nutrients and their applications -- Chapter 7. Development of highly sensitive optical sensors based on Carbon Nanotube (CNTs) -- Chapter 8. Recent advances of Fluorescent Resonance Energy Transfer-based nanosensors for the detection of human ailments -- Chapter 9. Application Of Nanosensors in Agriculture and Food Processing -- Chapter 10. Fluorescent Protein pairs and their application in FRET-based Nanobiosensors -- Chapter 11. Probes for Detection of Free Radicles -- .
    Abstract: This informative book compiles the most up-to-date applications of nanobiosensors in fields ranging from agriculture to medicine. The introductory section describes different types of nanobiosensors and use of nanobiosensors towards a sustainable environment. The applications are divided into four broad sections for easy reading and understanding. The book discusses how manipulation, control and integration of atoms and molecules are used to form materials, structures, devices and systems in nano-scale. Chapters in the book shed light on the use of nanosensors in diagnostics and medical devices. Application in food processing as well as in cell signaling is also described. Nanobiosensors have immense use, and this book captures the most important ones.
    Type of Medium: Online Resource
    Pages: XI, 223 p. 65 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811583469
    DDC: 660.6
    Language: English
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  • 47
    Keywords: Biotechnology. ; Bioinformatics. ; Medical genetics. ; Biotechnology. ; Computational and Systems Biology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Global Alignment of PPI Networks -- Chapter 2: Integrated Network-Based Computational Analysis for Drug Development -- Chapter 3: Effective Random Walk Models for Comparative Network Analysis -- Chapter 4: Computational Methods for Protein-Protein Interaction Network Alignment -- Chapter 5: Network Propagation for the Analysis of Multi_Omics Data -- Chapter 6: Motifs in Biological Networks -- Chapter 7: Bio Fabric Visualization of Network Alignments -- Chapter 8: Module Identification of Biological Networks via Graph Partition -- Chapter 9: Network Module Detection to Decipher the Heterogeneity of Cancer Mutations.
    Abstract: This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights. .
    Type of Medium: Online Resource
    Pages: XII, 217 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571733
    DDC: 660.6
    Language: English
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  • 48
    Keywords: Neurosciences. ; Neurology . ; Medical genetics. ; Neuroscience. ; Neurology. ; Medical Genetics.
    Description / Table of Contents: 1. Behavioural variant FTD: recent advances in the diagnosis and understanding of the disorder -- 2. The neuropsychiatry of frontotemporal dementia -- 3. Nosology and Neuropathology of Language in Primary Progressive Aphasia -- 4. Measuring Behavior and Cognition in FTLD -- 5. Clinical update on C9orf72: FTD, ALS and beyond -- 6. Clinical aspects of familial FTLD associated with MAPT and GRN mutations -- 7. Neuroimaging in Frontotemporal Lobar Degeneration -- 8. The FTD Prevention Initiative - linking together genetic FTD cohort studies -- 9. Fluid Biomarkers of Frontotemporal Lobar Degeneration -- 10. Cross-cultural perspectives on frontotemporal degeneration -- 11. Clinical characteristics and Neuropathology of PSP, CBD and Related 4R-Tauopathies -- 12. Tau protein and frontotemporal dementias -- 13. FTLD-TDP pathological subtypes: clinical and mechanistic significance -- 14. Lysosomal dysfunction as a pathogenic mechanism in FTD: Evidence from PGRN and TMEM106B genetics and biology -- 15. Future trends in understanding the pathological role of TDP-43 and FUS proteins -- 16. Description of a new data resource for FTD including multiomic data on human post mortem brain (MAPT, GRN, C9orf72), matching mouse models and iPS models -- 17. Mendelian and sporadic FTD: avenues from genetics to disease pathways through in-silico prediction and modeling -- 18. FTLD treatment: Current Practice and Future Possibilities.
    Abstract: Under the name of Frontotemporal Dementias (FTD) numerous hereditary and sporadic disorders are listed. FTD may take away speech and language, social skills and ethical judgement, wishes and will, empathy and emotions; it may also impair motor functions. FTD may affect men and women in midlife or during old age leading to the demolition of the uniqueness of the human mind. In the last decade of the 20th century and in the first two decades of the 21st century, progress in the understanding of clinical, neuropathological, biochemical, and genetic aspects of FTD has accelerated. The novel awareness about FTD has directed young generations of researchers toward the study of this complex group of disorders. This Volume has been formulated with the participation of some of the leading scientists who have contributed to the development of knowledge in the clinical and basic science arenas. It captures the current central elements that are relevant to an up-to-date understanding of causes and pathogenesis of multiple forms of FTD. The volume is an opus that represents a distillation of the work of many scientists and addresses the current directions in the study of one of the most complex groups of diseases. In view of its structure, the book could also be used as a textbook, that offers both a broad and deep analysis of major areas in FTD. This book, planned by the International Society for Frontotemporal Dementias, is distinctive as it opens a window to a wide landscape about the biology of FTD. Thus, the book represents a moment of reflection on the present state of our knowledge of FTD and a collective vision toward scientific progress. The authors of each chapter share their knowledge and vision aimed at reducing the suffering which is caused by FTD.
    Type of Medium: Online Resource
    Pages: X, 320 p. 46 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030511401
    Series Statement: Advances in Experimental Medicine and Biology, 1281
    DDC: 612.8
    Language: English
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  • 49
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Zoology. ; Biodiversity. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Ecology. ; Zoology. ; Biodiversity.
    Description / Table of Contents: Introduction: Christopher Clark and Ellen Garland -- Ch 1: Overview. Christopher Clark -- Ch. 2: Anatomy and physiology. Joy Reidenberg -- Ch. 3: Movement, Residency & Migration. Alex Zerbini and Sue Moore,- Ch. 4: Feeding strategies. Ari Friedlaender -- Ch. 5: Molecular genetics. Emma Carroll -- Ch. 6: Social organization. Peter Tyack -- Ch. 7: Ethological and bioacoustic variability. Christopher Clark -- Ch. 8: Baleen whale culture. Ellen Garland and Emma Carroll -- Ch. 9: Blue whale – Global diversity & behavioral variability in a specialist. Ana Sirovic -- Ch. 10: Humpback whale – Global diversity & behavioral plasticity in a court jester. Rebecca Dunlop -- Ch. 11: Humpback whale song - Global diversity & behavioral plasticity in a court jester. Danielle Cholewiak, Sal Cerchio and Ellen Garland -- Ch. 12: Bowhead whale – Acoustic variability in the almost-a-right whale that went north. Kate Stafford -- Ch. 13: Right whales - From north to south, what’s the big difference? Susan Parks -- Ch. 14: Minke Whale – Diversity and variability. Denise Risch -- Ch. 15: Omura’s Whale – An enigma. Sal Cerchio. .
    Abstract: In this book, an international team of leading marine mammal scientists, with a remarkably diverse set of backgrounds and areas of expertise, lead you through a synthesis of current knowledge on baleen whales. Baleen whales are the largest animals ever to have lived on this planet. They also have the lowest and most intense voices on Earth, most likely evolved to take advantage of ocean acoustic transmission conditions so as to be detectable across ocean basins. Some baleen whales can live to be 150-200 years old. They migrate many thousands of kilometers between feeding and breeding areas. They produce songs and calls that serve as behavioral foundations for establishing, maintaining and expanding their cultural identities. To conclude that we know the behavioral limits of these large brained, long-lived animals would be naïve. As baleen whale scientists, we are still beginning to comprehend the enormous complexities and natural histories of these remarkable animals. Today, the fact that whales sing is known throughout much of the world. This awareness started 50 years ago with the publication and popularization of a collection of humpback song recordings that motivated research into baleen whale behavioral ethology. In this book’s chapters, a reader’s experiences will stretch from learning about baleen whale laryngeal anatomy associated with their different voices to learning about the vast ocean areas over which their voices can be heard and the emerging complexities of their culturally defined societies. These are accompanied by chapters on the fundamental ethological contexts of socializing, migrating, and foraging. Two common themes permeate the book. One theme highlights the phenomenal increase in scientific knowledge achieved through technological advancements. The other theme recognizes the impacts of human-made activities on ocean acoustic environments and the resultant influences on the health and survival of individual whales and their populations. Although the book is intentionally ambitious in its scope, as scientists, we fully recognize that baleen whale science is still in its infancy. Many profound revelations await discovery by cohorts of young, multi-talented explorers, some of whom are stretching their wings in this volume and some of whom are reading these scientific stories for the first time.
    Type of Medium: Online Resource
    Pages: XVI, 384 p. 87 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030984496
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    DDC: 577.6
    Language: English
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    Keywords: Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Abstract: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Type of Medium: Online Resource
    Pages: XV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676062
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Stem cells. ; Nervous system Regeneration. ; Neuroscience. ; Stem Cell Biology. ; Regeneration and Repair in the Nervous System.
    Description / Table of Contents: 1 Regenerative Therapies in Ischemic Stroke Recovery -- 2 Application of Nanotechnology In Stroke Recovery -- 3 Nanotechnology: A daydream for advanced Imaging, Diagnosis and Therapeutic Approach for Cerebral Ischemia -- 4 Cell-Mediated Neurorestorative Mechanisms Underpinning Beneficial Effects in Ischemic Stroke -- 5 Induced Pluripotent Stem Cells for the Treatment of Neurodegenerative Disease: Current and Future Prospects -- 6 Imaging of Stem Cell Therapy for Stroke and Beyond -- 7 Nano-Medicine Mediated Stem Cell Therapeutics In Stroke -- 8 The Influence of Preconditioning on the Homing Behaviour of Stem Cells -- 9 Role of microRNAs in stroke pathology and recovery -- 10 Exosomes as a diagnostic tool and stem cells exosomes as a promising cell-based cell-free therapeutic tool for ischemic stroke 11 Role of nanomedicine in treating ischemic stroke -- 12 Insights into therapeutic targets in stroke -- 13 Signalling Pathways of Interest for Recovery from Ischemic Stroke.
    Abstract: This book illustrates the importance and significance of regenerative medicine in stroke recovery. It discusses stem-cell-based treatment strategies and offers mechanistic insights into their role in neurological recovery. It also examines the challenges and advances in using adult stem cells for enhanced therapeutic efficacy. Further, it presents the strategies as well as the strengths and weaknesses of various delivery methods to administer stem cells in ischemic stroke. It examines the role of non-coding RNA in our understanding the stroke pathogenesis, their regulatory role in ischemic stroke and potential as biomarkers and therapeutic targets. Lastly, it explores exosomes in the treatment of stroke, and the underlying mechanism of their action as therapeutic vectors for stroke. Given its scope, it is an excellent resource for neurologists, neuroscientists and researchers involved in regenerative therapy for stroke.
    Type of Medium: Online Resource
    Pages: XIII, 353 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811685620
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Cancer. ; Microtechnology. ; Microelectromechanical systems. ; Biomedical engineering. ; Biotechnology. ; Cancer Biology. ; Microsystems and MEMS. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Part 1 -- Conventional nanosized drug delivery systems for cancer applications -- Homing peptides for cancer therapy -- Radiolabeling of theranostic nanosystems -- Boosting nanomedicine efficacy with hyperbaric oxygen therapy -- Part 2 -- Mesoporous Silica Nanoparticles as Carriers for Biomolecules in Cancer Therapy -- Clearable Nanoparticles for Cancer Photothermal Therapy -- Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds -- Electrospun Nanofibers for Cancer Therapy -- Nanoneedle-based materials for intracellular studies -- Part 3 -- In vitro assays for nanoparticle-cancer cell interaction studies -- 3D tumor spheroid models for in vitro therapeutic screening of nanoparticles -- In vitro and in vivo tumor models for the evaluation of anticancer nanoparticles -- Part 4 -- Nanotechnology for the Development of Nanovaccines in Cancer Immunotherapy -- Viral nanoparticles: cancer vaccines and immune modulators -- Industrial Perspective on Cancer Immunotherapy -- Index.
    Abstract: The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.
    Type of Medium: Online Resource
    Pages: VIII, 360 p. 80 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030581749
    Series Statement: Advances in Experimental Medicine and Biology, 1295
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Biotic communities. ; Population biology. ; Evolution (Biology). ; Conservation biology. ; Ecology . ; Freshwater and Marine Ecology. ; Biodiversity. ; Ecosystems. ; Community and Population Ecology. ; Evolutionary Theory. ; Conservation Biology.
    Description / Table of Contents: The Coral Tree at the End of the World: Introductory Notes to Coralline Mythology and Folklore from the Indian and Pacific oceans -- The Marine Animal Forests Of South Africa: Importance For Bioregionalisation And Marine Spatial Planning -- Coral and reef fish communities in the thermally extreme Persian/Arabian Gulf: Insights into potential climate change effects -- Marginal reefs in the Anthropocene: they are not Noah’s Ark -- Animal Forests in Submarine Caves -- The Tubeworm Forests of Hydrothermal Vents and Cold Seeps -- Bryozoans: the ‘forgotten’ bioconstructors -- Polychaetes as habitat former: structure and function -- Chemical war in marine animal forests: Natural products and chemical interactions -- The nursery role of marine animal forests -- From Trees To Octocorals: The Role Of Self-Thinning And Shading In Underwater Animal Forests -- Marine animal forests as Carbon immobilizers or why we should preserve these three-dimensional alive structures -- Invasive alien species and their effects on marine animal forests -- Plastics, an additional threat for coral ecosystems -- Visual methods for monitoring mesophotic-to-deep reefs and animal forests: finding a compromise between analytical effort and result quality -- Advances in the Marine Animal Forests Scientific Outreach and Citizen Science.
    Abstract: Marine Animal Forests (MAFs) are spread all over the world. Composed by suspension feeding organisms (e.g. corals, gorgonians, sponges, bryozoans, bivalves, etc.), MAFs constitute a vast number of marine ecosystems such as coral reefs, cold water corals, sponge grounds, bivalve beds, etc. The surface covered by these systems is prominent (at the scale of the oceans of the planet), though poorly known. In a previous book (Marine Animal Forests, the ecology of benthic biodiversity hotspots), several aspects of the MAFs were described and discussed, building the basis for a holistic approach with the aim of putting these shallow and deep sea ecosystems under a common umbrella. The main target of the present book is to identify and address important topics which were not covered in the previous three volumes. Bryozoans or Polychaeta, for example, are treated in this volume, as well as hydrothermal vents ecosystems and submarine caves, the chemical ecology in MAFs or the nursery effect on these ecosystems. The vastity of the MAF concept opens new insights in the biology, physiology, biodiversity of the organisms structuring these highly biodiverse ecosystems and on the dangers threatening them (such as microplastics or the role of invasive species as an impact of their trophic ecology or distribution). In a fast changing world, in which the complexity of MAFs is at risk, we propose an in-depth analysis of many aspects that may be inspirational for future research lines in marine biology and ecology.
    Type of Medium: Online Resource
    Pages: XII, 530 p. 120 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030570545
    DDC: 577.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Industrial microbiology. ; Food Microbiology. ; Pharmaceutical chemistry. ; Biotechnology. ; Industrial Microbiology. ; Food Microbiology. ; Pharmaceutics.
    Description / Table of Contents: Module 1. Introduction -- Module 2. Screening of Biosurfactants -- Module 3. Commercial production, optimization and purification -- Module 4. Industrial and environmental applications -- Module 5. Role of biosurfactants in Agriculture and soil reclamation -- Module 6. Toxicity assessment.
    Abstract: This book illustrates the importance and significance of the biosurfactants obtained from microorganisms, preferably from bacteria and yeast. It explains the superiority of biosurfactants (green molecule) over chemically synthesized surfactants for the sustainable future. The content of the present book addresses the quest for novel biosurfactants producing strains, high throughput screening methods, and production strategies. It finely describes the aptness of biosurfactants for industrial and environmental applications. It elaborately describes the technical background and cutting-edge advancement of the commercial aspect of biosurfactants. In the later part of the book, the role of green biosurfactants in food processing, control of food spoilage, incorporation in personal health care products, environmental and agricultural remediation are discussed. Finally, the book elucidates a comprehensive and representative description of toxicity assessment of the biosurfactants, which highlights the risk assessment of the incorporation of the microbial biosurfactants in food, healthcare, and pharmaceutical formulations.
    Type of Medium: Online Resource
    Pages: XI, 194 p. 54 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811627057
    DDC: 660.6
    Language: English
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    Keywords: Neurosciences. ; Biotechnology. ; Cognitive psychology. ; Nonlinear Optics. ; Neuroscience. ; Biotechnology. ; Cognitive Psychology. ; Nonlinear Optics.
    Description / Table of Contents: Neural Dynamics in Motor and Sensory Systems and in Cognitive Functions -- Cognitive Network and Multi-Scale Neural Network Dynamics -- Neuroengineering, Neuroinformation and Brain Computer Interaction -- Modelling Higher-Order Functions and Dysfunctions -- Oscillation, Synchronization, Neural Plasticity, and Coordination Dynamics from Neural to Social Systems.
    Abstract: This book contains original articles submitted to the Seventh International Conference on Cognitive Neurodynamics (ICCN 2019). The brain is an endless case study of a complex system characterized by multiple levels of integration, multiple time scales of activity, and multiple coding and decoding properties. The contribution of several disciplines, mathematics, physics, computer science, neurobiology, pharmacology, physiology, and behavioral and clinical sciences, is necessary in order to cope with such seemingly unattainable complexity that transforms the experimental information into a tricky puzzle which hides the correspondence with model predictions. This conference gathered active participants to discuss ideas and pose new questions from different viewpoints, ranging from single neurons and neural networks to animal/human behavior in theoretical and experimental studies. The conference is organized with plenary lectures, mini-symposia, interdisciplinary round tables, and oral and poster sessions.
    Type of Medium: Online Resource
    Pages: XIX, 293 p. 97 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811603174
    Series Statement: Advances in Cognitive Neurodynamics,
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Cognitive neuroscience. ; Social evolution. ; Neuroscience. ; Cognitive Neuroscience. ; Social Evolution.
    Description / Table of Contents: Part I Differentiation-Integration Dynamics: Ultimate Causes -- Chapter 1: Introduction -- Chapter 2: Purposeless Design -- Chapter 3: Darwinian Evolutionary Theory -- Chapter 4: Principles of Differentiation and Integration -- Chapter 5: The Information Trend in Science -- Chapter 6: Is Social Cohesion a Different Mechanism of Evolution? -- Part II Roots and Mechanisms: Proximate Causes -- Chapter 7: Fundamental Physical Forces, Genes, and Epigenetics -- Chapter 8: Biological Origins -- Chapter 9: Neural Mechanisms of Sociality -- Chapter 10: Psychological Features -- Chapter 11: Cognitive Science Underpinnings -- Chapter 12: A Sociological Systems Theory -- Chapter 13: Developmental Roots -- Chapter 14: Metaphysical, Religious, and Spiritual Aspects -- Part III Survival Value -- Chapter 15: Sociality’s Survival Value -- Part IV Conclusions -- Chapter 16: A New Framework: A Theory of Integration.
    Abstract: This book is an exploration of the integration-differentiation dynamics that result in a drive, or impulse, toward human sociality, arguing that our need to connect with other people is as fundamental as our need for food and shelter. In The Social Impulse: The Evolution and Neuroscience of What Brings Us Together, Jaime Pineda presents the evidence that social cohesion is a complementary force to natural selection, the Darwinian drive for differentiation and diversity. The book addresses the distinctive aspects of social behavior that arise from integration principles and seeks to answer the following questions: (1) Why does social cohesion arise? (2) What is the history of social dynamics? (3) How does social cohesion work? (4) When do the developmental aspects of social dynamics arise? A final section of the book addresses the value of sociality and social cohesion. By exploring the differences, similarities, and, most important, the interactivity between natural selection and social cohesion, this unique book provides a wealth of interesting, challenging, and unexpected insights.
    Type of Medium: Online Resource
    Pages: XXV, 190 p. 7 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084393
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biotic communities. ; Biodiversity. ; Population biology. ; Microbial ecology. ; Freshwater and Marine Ecology. ; Ecosystems. ; Biodiversity. ; Community and Population Ecology. ; Microbial Ecology.
    Description / Table of Contents: Chapter 1 Lake Alchichica: History of Human Settlements -- Chapter 2 Geological Evolution of the Alchichica Crater -- Chapter 3 Paleoenvironmental Change in Central Mexico During the Last 20,000 Years -- Chapter 4 Recent Climate of Serdán-Oriental Basin -- Chapter 5 Hydrogeology and Hydrochemistry of the Serdán-Oriental Basin and the Lake Alchichica -- Chapter 6 Meteorological Regime, Local Climate, and Hydrodynamics of Lake Alchichica -- Chapter 7 Physicochemical Characteristics -- Chapter 8 The Littoral Environment -- Chapter 9 Aquatic Vegetation -- Chapter 10 The Littoral Community -- Chapter 11 Bacterioplankton -- Chapter 12 -- Phytoplankton of Alchichica: A Unique Community for an Oligotrophic Lake -- Chapter 13 Protozooplankton -- Chapter 14 Metazooplankton: The Joys and Challenges of Living in a Saline, Oligotrophic, Warm Monomictic Lake -- Chapter 15 Alchichica Silverside -- Chapter 16 -- The Axolotl of Alchichica -- Chapter 17 The Deep Benthic Zone. - Chapter 18 Lake Metabolism. - Chapter 19 Lake Food Webs -- Chapter 20 Diversity and Endemisms -- Chapter 21 Conservation Actions -- Chapter 22 Microbialites: Diversity Hotspots in the Mexican Plateau -- Chapter 23 The Lake Alchichica from an Astrobiological Perspective -- Chapter 24 Lake Alchichica Traditions, Myths, and Legends: Interviews with Local Residents. .
    Abstract: The book provides a comprehensive account of a tropical lake, Alchichica, considering that tropical limnology is by far less well-understood than temperate. Many of the well-known temperate limnology paradigms do not apply in tropical limnology, such as the ≥ 1ºC/m thermocline concept, or the role of phosphorous as limiting nutrient. Lake Alchichica is - most likely – the best limnologically known Mexican lake up to date. Twenty years of continuous monitoring has led us to understand this deep, warm monomictic lake. The peculiar chemical composition of this saline lake – sodium-alkaline with high concentration in magnesium waters, and groundwater-fed – led to the formation of its unique stromatolite ring that has become world-famous, studied by scientists from various countries. From a biological point of view, this relatively small maar lake displays a low species richness, but surprisingly is plentiful in microendemic species for a recently-formed lake (12,000 years old, at the onset of Holocene Epoch), eleven of which already described, with more to come. Researchers and students interested in tropical limnology, extreme ecosystems, evolutionary biology, and microbiology will find this book a must-read.
    Type of Medium: Online Resource
    Pages: XXI, 433 p. 179 illus., 144 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030790967
    DDC: 577.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Pain medicine. ; Clinical psychology. ; Neuroscience. ; Pain Medicine. ; Clinical Psychology.
    Description / Table of Contents: Chapter 1. Conceptualising Pain in Critically-Ill Neonates or Infants -- Chapter 2. Pain in the Fetus and the Preterm Baby -- Chapter 3. Developmental Influences on the Meanings of Pain in Children -- Chapter 4. “Ooh, You Got to Holler Sometime:” Pain Meaning and Experiences of Black Older Adults -- Chapter 5. Exploring the Meaning of Chronic Low Back Pain as a Life of ‘Living Death’ in Rural Nigeria -- Chapter 6. Painworld: A Phenomenological View of Veteran Experiences of Living with Chronic Pain -- Chapter 7. “It’s Just One of Them Things You’ve Got to Try and Manage”: Meanings of Pain for People with Brain Injury.
    Abstract: This book, the third and final volume in the Meaning of Pain series, describes what pain means to people with pain in “vulnerable” groups, and how meaning changes pain – and them – over time. Immediate pain warns of harm or injury to the person with pain. If pain persists over time, more complex meanings can become interwoven with this primitive meaning of threat. These cognitive meanings include thoughts and anxiety about the adverse consequences of pain. Such meanings can nourish existential sufferings, which are more about the person than the pain, such as loss, loneliness, or despair. Although chronic pain can affect anyone, there are some groups of people for whom particular clinical support and understanding is urgently needed. This applies to “vulnerable” or “special” groups of people, and to the question of what pain means to them. These groups include children, women, older adults, veterans, addicts, people with mental health problems, homeless people, or people in rural or indigenous communities. Several chapters in the book focus on the lived experience of pain in vulnerable adults, including black older adults in the US, rural Nigerians, US veterans, and adults with acquired brain injury. The question of what pain experience could mean in the defenceless fetus, neonate, pre-term baby, and child, is examined in depth across three contributions. This book series aspires to create a vocabulary on the “meanings of pain” and a clinical framework with which to use it. It is hoped that the series stimulates self-reflection about the role of meaning in optimal pain management. Meanings of Pain is intended for people with pain, family members or caregivers of people with pain, clinicians, researchers, advocates, and policy makers. Volume I was published in 2016; Volume II in 2019.
    Type of Medium: Online Resource
    Pages: VII, 147 p. 5 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030958251
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Religion and sociology. ; Biotechnology. ; Biotechnology. ; Sociology of Religion.
    Description / Table of Contents: Preface -- Geography, Economy and Nationality of Shimenkan of Weining -- Methodist Churches in Zhaotong -- Shimenkan and Christianity -- Governance of the Miao nationality by the national government in Weining -- The Miao Nationality in Weining in Early People's Republic of China -- Social Reform of the Miao nationality in Weining -- Cooperative and People's Movement in Weining -- Socialist Education Movement" and "the Cultural Revolution" in Weining -- Reform and Opening up of Weining -- Shimenkan after Reform and Opening up -- Conclusion.
    Abstract: This book explores Shimenkan—a Miao-inhabited area in Weining County, China—and its rural society from a comprehensive and long-term perspective, drawing on research conducted by the author in the course of ten years. Located in the northwest of Weining County in Guizhou Province, Shimenkan is a multiethnic area, where, e.g., the Hans, Miaos, Yis, Huis, and Buyis live. Until the early twentieth century, it was a small mountain village; the introduction of Christianity led to significant cultural and social changes in this area. Focusing on China in the twentieth century, the book addresses the traditional culture of the Miao people, the popularity of Christianity in early modern times, the management and control by the government, the socialist reform in the period of the People’s Republic of China, and the changes following the reform and opening-up in recent years. Covering a century’s worth of history, it discusses the major historical events in Northeastern Yunnan and Northwestern Guizhou around Shimenkan and analyzes local social structures, religions, ideologies, customs, and ethnic psychologies, making it a valuable addition to the study of regional social history. The book draws on archives, literature reviews, and field surveys and pursues a multi-disciplinary approach combining history, anthropology, and other disciplines. It offers a valuable resource for researchers in history, religion, and ethnology, as well as readers interested in the spread of Christianity in the Miao-inhabited areas of southwestern China.
    Type of Medium: Online Resource
    Pages: XIV, 273 p. 45 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811989834
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Feminism. ; Feminist theory. ; Economic development. ; Biotechnology. ; Feminism and Feminist Theory. ; Development Studies.
    Description / Table of Contents: 1. Introduction -- 2. Environment as a feminist issue -- 3. Silesian coal: history of Silesian industrialisation, the emergence of industrial society and its present restructuring -- 4. Silesian modernizations: analysis of the discourses of change -- 5. Coal perception in the region -- 6. Silesian narratives about the energy and ecology -- 7. The changing roles and values of Silesian women -- 8. Silesian women’s identity: the might of myth -- 9. Women's activity: "I" towards the change -- 10. Post-coal Silesia – the emergence of new regional identity -- 11. Upper Silesia: towards a sustainable future?.
    Abstract: This volume takes an ecofeminist perspective in analysing societal changes related to energy transition, with a focus on Upper Silesia in Europe, following the closure of coal-mining industries in the region. It provides both a macro and micro view of how energy transition in societies built around an energy industry can lead to major shifts in societal and familial dynamics, and how women locate themselves in this transition period affecting the economy as well as social and environmental structures and values. Densely populated Upper Silesia in southern Poland, with one of the longest histories of industrialization, extractivism and environmental degradation in Europe, can be considered as a microcosm of regions that have undergone such changes due to energy transition. The traces of telling socio-economic changes, as well as the tangle of modernity and conservatism, are both clearly visible in the local region and society. The book documents the Silesian changes and highlights the female perspective: their culture, identities, as well as empowerment and the agency. The paradigm of feminist and masculinity studies helps in presenting the complexity and the challenges of the just energy transition. This is a topical volume, given that many regions of the world are undergoing similar changes, and is an interesting read for decision-makers, policy experts, environmentalists, as well social scientists who study issues related to sustainability and environmental/societal challenges in energy transition. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030784164
    DDC: 660.6
    Language: English
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    Keywords: Freshwater ecology. ; Marine ecology. ; Invertebrates. ; Biotic communities. ; Biodiversity. ; Applied ecology. ; Water. ; Hydrology. ; Freshwater and Marine Ecology. ; Invertebrate Zoology. ; Ecosystems. ; Biodiversity. ; Applied Ecology. ; Water.
    Description / Table of Contents: Preface -- Chapter 1: Evolution of Bilateria from a Meiofauna Perspective – Miniaturization in the Focus -- Chapter 2: Meiofauna Shaping Biogeochemical Processes -- Chapter 3: Meiofauna and Biofilms – the Slimy Universe -- Chapter 4: Meiofauna Meets Microbes: Chemosynthetic Symbioses -- Chapter 5: Marine Meiofauna Diversity and Biogeography – Paradigms and challenges -- Chapter 6: Freshwater Meiofauna – a Biota with Different Rules? -- Chapter 7: Hidden Players – Meiofauna Mediates Ecosystem Effects of Anthropogenic Disturbances in the Ocean -- Chapter 8: Deep-Sea Meiofauna – a World of its Own or Deeply Connected? -- Chapter 9: Polar Meiofauna – Antipoles or Parallels? -- Chapter 10: Cave Meiofauna - Models for Ecology and Evolution -- Chapter 11: Meiofauna – Adapted to Life at the Limits -- Concluding Remarks -- Index.
    Abstract: Since research on meiobenthos was last compiled in a textbook (2008/2009), the number of theoretical and applied studies has been growing rapidly. Supported by new methods and digital evaluation, meiobenthology has developed into a wide field, with more and more researchers studying cross-disciplinary aspects. New perspectives were summarized in a booklet (2019) to draw attention to promising research directions. The present book, written by leading experts, is a compilation of new thinking, data, methods and approaches in many relevant fields of recent meiobenthos research. The topics addressed range from bacteria and biofilms to globally changing processes, from polar regions to the deep-sea and from freshwater ecosystems to the ocean. So, this book is not simply another meiobenthos textbook - it is an attempt to identify new horizons in meiobenthos research, driven by the vision of advancing knowledge and understanding of benthic ecosystems.
    Type of Medium: Online Resource
    Pages: XII, 407 p. 49 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031216220
    DDC: 577.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry.
    Description / Table of Contents: 1.How Immune-inflammatory processes link neurodegenerative and psychiatric disorders -- 2.Gut-Microbiota-Brain Axis: pathophysiological mechanism in neuropsychiatric disorders -- 3.Microbiome- induced autoimmunity and novel therapeutic intervention -- 4.The key role of microlia and circulating monocytes in etipathology neuropsychiatric disorders -- 5.Neuro-immuno-epigenetics of prenatal psychological stress -- 6.C-reactive protein (CRP): a potent inflammation biomarker in psychiatric disorders -- 7.Neuroinflammation, neurognesis and neuroprotection in schizophrenia -- 8.Autoimmue psycosis: concept, clinical manifestation and management -- 9.Stress, autonomic nervous system and kynurenine pathway in major depression -- 10.Brain-gut-microbiome axis in major depression : novel therapeutic approach -- 11.Glial-Neuronal Interaction in Synapses: A Possible Mechanism of the Pathophysiology of Bipolar Disorder -- 12.Neuroimmaging of inflammation in depression and anxiety disorders -- 13.Neuroinflammation and immune-kynureinine pathway in anxiety disorders -- 14.Inflammatory-mediated responses in development of neurogeneartive diseases -- 15.The connection between gut-brain axis and PTSD -- 16.Eating disorders : Gut microbiota-immune-brain interactions -- 17.Sleep-immune crosstalk and sleep disorders -- 18.Obsessive-compulsive disorder: immuno-inflammatory disorder? -- 19.Cytokine, neuroinflammation and neurodeneration in Alzheimer’s disease -- 20.Molecular imaging of neuroinflammation in Alzheimer's disease and MCI -- 21.The role of N-Methyl-D-Aspartate Receptor Neurotransmission and mictobiota in Alzheimer’s disease -- 22.Neuroglial activation and neuroinflammation in the brain of patients with autism -- 23.Suicide and inflammation -- 24.Anti-inflammatory effect of Traditional Chinese Medicine on the concept of Mind-body interface -- 25.Anti-inflammatory therapy as a promising target in neupsychiatric disorders.
    Abstract: This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.
    Type of Medium: Online Resource
    Pages: XVII, 554 p. 28 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811973765
    Series Statement: Advances in Experimental Medicine and Biology, 1411
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurophysiology. ; Gastroenterology. ; Neuroscience. ; Neurophysiology. ; Gastroenterology.
    Description / Table of Contents: Tools for optogenetic probing of nociceptive pathways; Monitoring activity -- An open science model to accelerate the generation, implementation and distribution of optogenetics and viral tools -- Vagal neuroinflammation accompanying respiratory viral infection: An overview of mechanisms and possible clinical significance -- Stress-induced Visceral Analgesia: Concept and Pathways -- Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders -- EPIGENETIC REGULATION OF STRESS-INDUCED VISCERAL PAIN -- The biomechanics and mechanotransduction in visceral nociception -- VISCERAL NOCICEPTION IN GASTROINTESTINAL DISEASE -- Epithelial-Neuronal Communication in Visceral Pain -- Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome -- A fentanyl analogue that activates u-opioid receptors in acidified tissues inhibits colitis pain without opioid side effects -- Signalling in the Gut -- Translating colonic sensory afferent peripheral mechanosensitivity into the spinal cord dorsal horn -- Translating colonic afferent peripheral sensitivity into the spinal cord dorsal horn -- Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain -- Pre-clinical Models of Endometriosis -- Spinal afferent innervation of the uterus -- Post-infectious bladder hypersensitivity in the development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
    Abstract: The chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field.
    Type of Medium: Online Resource
    Pages: VIII, 255 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031257025
    DDC: 612.8
    Language: English
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  • 64
    Keywords: Biotechnology. ; Religion and sociology. ; Biotechnology. ; Sociology of Religion. ; Biotechnology.
    Description / Table of Contents: Introduction -- Chapter 1. Religion outside one’s homeland -- Chapter 2. Asylum seekers, immigrants, new Europeans: setting the scene -- Chapter 3. Young foreign Christian Catholics: a portrait -- Chapter 4. Being Muslim in Hard Times in Europe: New Opportunities and Old Challenges -- Chapter 5. God will save us! Faith, identity and practices in refugee welcoming centers -- Chapter 6. Similarities and differences: the Me3 generation at the mirror -- Chapter 7. Does religious capital still matter? Local secularized societies face with a renewal of religious pluralism -- Concluding remarks.
    Abstract: This monograph considers the Catholic/Christian religious identity of young immigrants within the migratory diasporas in Southern Europe. It details important ethnographical work on various groups, such as the family, ethnic communities, and peers. The author also considers the role of institutional figures in mainstream society. These include teachers, administrators, and social workers. This valuable research material helps readers to better understand the viewpoint of young people (especially the children of immigration) in relation to various environments which are important in their lives. The investigation examines theoretical and practical questions regarding the study of relations between religion and migrations. It pays particular attention to both the youth perspective and the effects of the current refugee crisis on the perception of religious diversity and identity. Coverage also looks at similarities and differences between young migrant and their native peers. In addition, three case studies further help illustrate the main points of the author's argument. The book uses preliminary research carried out in Italy. It also features interviews collected in Portugal and Spain. Those interviewed include people with migratory background who are permanent residents, belong to the second generations, or are recently-arrived asylum seekers. Overall, the author provides readers with an interesting and innovative portrait of children of immigrants and their relations with faith in the post-secularized Europe: indeed, by considering both academic debates and original empirical data, the book offers the possibility of reframing the link between migrations and religious identities. .
    Type of Medium: Online Resource
    Pages: XXVII, 130 p. 5 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030840563
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Medical genetics. ; Biotechnology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Brief Introduction to CRISPR Cas 9 -- Chapter 2: Introduction To Anticipatory Ethics -- Chapter 3: CRISPR, Phenomenology and Lived Experience -- Chapter 4: CRISPR and the Concept of Personhood -- Chapter 5: The use and access to CRISPR in historically socio-economically disadvantaged and marginalized communities -- Chapter 6: Future use of CRISPR: Gene Drive -- Chapter 7: Future use of CRISPR II: CRISPR Kill Switches -- Chapter 8: Domestic and International Regulation of CRISPR -- Chapter 9: Policy Recommendations with respect to CRISPR Germline Editing in Humans -- Chapter 10: Conclusions.
    Abstract: Can we move forward with the use of CRISPR in humans without a well-formed policy and ethical framework to support it? In this new book, neuroscientist Michael W. Nestor and philosopher Richard Wilson argue that the answer is a resounding “no.” Does an ethical and policy program need to be restrictive concerning the use of CRISPR in humans? Nestor and Wilson argue that, although the future of gene editing in humans is inevitable using CRISPR technologies, the scientific, policy, ethics, and clinical communities must work together to provide the necessary frameworks to help CRISPR flourish as an essential tool to treat human disease. To achieve the most inclusive, equitable, and ethically sound use of CRISPR in humans, the scientific/policy/clinical community must involve the most comprehensive set of stakeholders possible, including the lay public. This book sets a framework for shared understanding and discussion across disciplines with an appeal to scientists and non-scientists alike. The authors urge all stakeholders to engage in active dialogue about the appropriate context for using CRISPR and other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, exploring its positive potential to treat mental disorders and the potential to induce other cognitive enhancements.
    Type of Medium: Online Resource
    Pages: XIX, 145 p. 13 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030983680
    DDC: 660.6
    Language: English
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    Keywords: Neurosciences. ; Materials Analysis. ; Imaging systems. ; Nervous system Diseases. ; Nervous system Radiography. ; Neuroscience. ; Imaging Techniques. ; Neurological Disorders. ; Neuroradiology.
    Description / Table of Contents: Optical coherence tomography in brain gliomas detection and peritumoral white matter state evaluation -- Two Photon Fluorescence Lifetime Imaging of Reduced nicotinamide adenine dinucleotide in Brain Research -- Types of Raman Scattering Techniques for Neurodegenerative Diseases -- Drosophila brain advanced multiphoton imaging -- Myelin imaging -- Brainbow: Principle, Technique and Applications -- Photoacoustic Imaging of Brain -- Photodynamic therapy of brain diseases -- Advanced Magnetic Resonance Imaging (MRI) of Brain -- Indirect imaging -- Multimodal Noninvasive Imaging Strategies for Clinically Monitoring Degenerative Disorders of the Brain -- Machine learning approach in brain imaging -- Transgenic Brain mapping Techniques in Drosophila melanogaster -- Behavioural phenotyping to study cognitive and non-cognitive symptoms in the rodent model of Alzheimer's disease.
    Abstract: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.
    Type of Medium: Online Resource
    Pages: XII, 257 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913525
    DDC: 612.8
    Language: English
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    Keywords: Biotechnology. ; Refuse and refuse disposal. ; Environmental engineering. ; Bioremediation. ; Renewable energy sources. ; Biotechnology. ; Waste Management/Waste Technology. ; Chemical Bioengineering. ; Environmental Engineering/Biotechnology. ; Renewable Energy.
    Description / Table of Contents: Part I: Introduction -- Chapter 1. Sustainable technologies for recycling organic solid wastes -- Part II: Production of Biofuels and Chemicals by Thermo-chemical Conversion Processes -- Chapter 2. Recent advances in the catalytic co-pyrolysis of lignocellulosic biomass and different polymer wastes: from laboratory scale to pilot plant -- Chapter 3. Roadmap to Low-Cost Catalytic Pyrolysis of Plastic Wastes for Production of Liquid Fuels -- Chapter 4. Production of Valuable Compounds from Leaves by Supercritical CO2 Extraction -- Part III: Production of Biofuels and Chemicals by Biodegradation -- Chapter 5. Recovery of biohydrogen and biomethane by anaerobic fermentation of organic solid waste -- Chapter 6 Recycling of multiple organic solid wastes into biogas via anaerobic digestion -- Chapter 7. Recycling of multiple organic solid wastes into chemicals via biodegradation -- Part IV Production of Liquid Biofuels with New Technologies -- Chapter 8. Producing value-added products from organic bioresources via Photo-BioCatalytic processes -- Chapter 9. Depolymerisation of fossil fuel and biomass-derived polyesters -- Chapter 10 Producing Value-added Products from Organic Solid Wastes with Mechanochemical Processes -- Chapter 11. Fundamentals of Hydrothermal Processing of Biomass-Related Molecules for Converting Organic Solid Wastes into Chemical Products -- Chapter 12 Third Generation Biorefineries Using Micro- and Macro-Algae -- Part V. Techno-Economic Analysis -- Chapter 13. Prospects and perspectives for producing biodiesel, bioethanol and bio-chemicals from fruit waste: Case study in Brazil and Serbia -- Chapter 14. Sustainable Recycling and Valorization of Organic Solid Wastes for Fuels and Fertilizers.
    Abstract: This book covers sustainable recycling processes (e.g. physical, biological, chemical, and thermo-chemical) of multiple organic solid wastes, provides methods for material recycle of wastes into value-added products including fuels and commodity chemicals that are able to be directly applied to promote manufacturing processes. Aimed at improving the awareness of effective conversion protocols and for developing innovative biomass conversion processes, this text was conceived as a collection of studies on state-of-art techniques and know-how for production of biofuels and chemicals from sustainable recycling of organic solid wastes. Topics in the text are discussed in terms of addressing recent advances, assessing and highlighting promising new methods or new technological strategies and direct conversion of organic solid wastes to process feeds. Highly-recognized authorities, experts and professionals have contributed individual chapters in selected areas to cover the overall topic in a comprehensive manner. .
    Type of Medium: Online Resource
    Pages: XVII, 506 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811661624
    Series Statement: Biofuels and Biorefineries, 11
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Psychiatry.
    Description / Table of Contents: Part 1: Considering sex and gender in research studies -- Sex and Gender Science -- Best practices in the study of sex? -- Best practices in the study of Gender Differences -- The special case of a lack of sex differences – the naked mole rat? -- Lateralization and -- Part 2: Sex differences in cognitive and mental health across the lifespan -- Depression -- Schizophrenia -- Immune and neurodevelopmental disorders – autism? -- Social Cognition -- Cognition and cognitive ageing -- Part 3: Diseases of the brain and relevance of sex -- Epilepsy -- Stroke -- AD -- Parkinson’s -- Multiple Sclerosis.
    Abstract: Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines of psychology, neuroscience, psychiatry and neurology. Understanding how brain function and resultant behaviors may differ between the sexes impacts upon our knowledge of the pathology and development of treatments for various neurological and psychiatric disorders, particularly those that show significant sex differences in either prevalence and/or manifestation of symptoms. This volume covers three main themes of research into sex differences in basic neurobiology, psychology, preclinical research and clinical research. It begins by exploring our understanding of sex and gender in relation to both animal and human behaviors and discusses the relevance, and importance, of considering sex and gender when conducting research into brain function and behaviors. The second theme focuses on how sex and gender influence mental health and considers the impact of our immune system and the changes that occur with ageing. Finally, the third aspect focuses on examples of neurological disorder which show sex differences in terms of their aetiology and/or symptomology and considers the relevance in the development of treatment for these disorders including dementia, stroke and multiple sclerosis. This volume is of considerable interest to mental health and neurology professionals, including psychiatrists, neurologists, nurses, allied health clinicians and pharmacists. It is also helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology.
    Type of Medium: Online Resource
    Pages: X, 373 p. 70 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031267239
    Series Statement: Current Topics in Behavioral Neurosciences, 62
    DDC: 612.8
    Language: English
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    Keywords: Biotechnology. ; Biomaterials. ; Biology Technique. ; Biotechnology. ; Biomaterials. ; Biological Techniques.
    Description / Table of Contents: Introduction to Biobanking -- Scientific Relevance, Problems and the Destitution for Principles of Biobanks and Biobanking Activities -- Types of Biobanks -- Ethical and Legal Principles in the Field of Biobanking -- Business Planning for Biobanks -- Biobanking Concepts Specific for Developing Countries -- Methods of Implementation and Set-up of National Biobanking Networks -- Implementation of Ethical and Legal Considerations in a Biobanking Network -- Collection and Management of Samples -- Quality Control and Risk Management in Biobanks -- Governance and Stakeholder Analysis -- Biobanking IT Systems, Database Structure and Web Applications -- Management Model and Sustainability Plan of Biobanks -- Sustainability Plan and Project Management of a Biobanking Network -- Establishing a Biobank Using Standardisation -- Science and Innovation of Biobanks -- Running a Biobank Network -- Infrastructure: Delivering on the Promise of Biobanking -- Design Considerations and Equipment of Biobanks -- Software Tools for Biobanking in LMICs -- The Importance of Cancer Biobanks in Low- and Middle-Income Countries -- Biobanking in Paediatrics: A Look from Armenia as a Middle-Income Country -- Biobanking of the Central Nervous System -- The Importance of Biobanking COVID-19 Samples -- Oncobiobanking in a Middle-Income Country: The Example of Russia -- Sustainability of Biobanks and Biobanking in LMICs -- Biobanks for Enabling Research and Development by Trusted Patient Data Environment -- Future Perspective of the Biobanking Field.
    Abstract: This book introduces the fundamentals of biobanking and guides through the practical planning thereof, with a special focus on the situation in low- and middle-income countries. On the example of the setup of a Ukrainian biobank the book discusses the main steps and aspects of successful biorepository implementation and management. Topics covered include collection, storage and shipping of samples, establishment of an IT system, development of a sustainability plan, and project and risk management. Furthermore, the importance of the formation of international biobanking societies such as the Ukraine Association of Biobanks is highlighted, and their main objectives and tasks are discussed. The book addresses life science and business professionals as well as national authorities who are interested in biobanking in general and in setting up a biobank in particular.
    Type of Medium: Online Resource
    Pages: XVII, 235 p. 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030876371
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Lipids. ; Food science. ; Biotechnology. ; Lipidology. ; Food Science.
    Description / Table of Contents: Chapter 1. Vegetable Oils and Animal Fats: Sources, Properties and Recovery -- Chapter 2. Exotic Oil: Sources, Properties and Recovery -- Chapter 3. Seed Oil: Sources, Properties and Recovery -- Chapter 4. Vegetable Oil Refining -- Chapter 5. MINOR COMPONENTS IN EDIBLE OIL -- Chapter 6. Blending, Hydrogenation, Fractionation and Interesterification Processing -- Chapter 7. Ionic Liquid as a Green Solvent for Lipid Processing -- Chapter 8. Diacylglycerol Oil: Health Benefits, Synthesis and Applications -- Chapter 9. Medium-and Long-Chain Triacylglycerol: Production, Health Effects and Applications -- Chapter 10. Enzymatic synthesis of human milk fat substitutes -- Chapter 11. Cocoa Butter Alternatives for Food Applications -- Chapter 12. Oleogel: Production and Application -- Chapter 13. Characterization of Nanoemulsions: The Way Forward -- Chapter 14. Processing Contaminants In Edible Oil -- Chapter 15. Enzymatic Biodiesel Production from Low-Quality Waste Oils and Non-edible Oils: Current Status and Future Prospects -- Chapter 16. Sustainability and Traceability in the Malaysian Oil Palm Industry -- Chapter 17. Adulteration in Oils and Fats Industry.
    Abstract: This book is written by international experts with both academic and industrial credentials. It presents for the first time, a collection of up-­to-­date scientific advances in the area of edible fats and oils technology, over a span of 10 years from 2009 to the year 2019. The book covers the existing and recent advanced techniques adopted in the edible fats and oils research and touches on the processing and modification, to the traceability and sustainability issues of fats and oils. Some recent technologies like supercritical carbon dioxide, microwave, ultrasound, and enzymatic‐ assisted processes, ionic liquid, enzymatic processes, biosensor and membrane technology are presented in the book. The book aims to provide the technologists and researchers in research, development and operations in the edible fats and oils industries with critical and readily accessible information on the recent advances in the field. The book is divided into three broad sections- Fats and Oils Chemistry and Processing, Fats and Oils Modification and Health Implications, and Fats and Oils Safety, Social, Environmental and Economic Impacts. It is an extremely comprehensive and valuable resource, which serves as an essential reference for students and lipid scientists from academia or industry.
    Type of Medium: Online Resource
    Pages: X, 492 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811651137
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Zoology. ; Behavior genetics. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Ecology. ; Biodiversity. ; Zoology. ; Behavioral Genetics.
    Description / Table of Contents: Evolution – Analisa Berta -- Sensory and cognition – Tentative Colleen Reichmuth and others -- Communication – Isabelle Charrier -- Physiology – Dan Crocker -- Movement – Luis Huckstadt and Ryan Reisinger -- Navigation – Patrick Robinson -- Foraging ecology and behavior – Don Bowen -- Reproductive behavior and lactation strategies – Dan Costa and Jen Maresh -- Breeding behavior – Paddy Pomeroy and Kelly Robinson -- Conservation – Samantha Simmons and others.
    Abstract: Phocid (or earless or true) seals are ecologically diverse, occupying habitats from the tropics to the poles in marine and freshwater and feeding on anything from tiny zooplankton to other marine mammals. There are 18 species of phocid seals, the smallest species (ringed seal) is more than 20 times smaller than the largest (southern elephant seal), with marked sexual dimorphism present in some species. This book examines the behavior, ecology, and physiology that allow phocid seals to inhabit such a wide range of habitats. The book is composed of 16 chapters written by 37 authors from 8 countries. The book first describes the general patterns of phocid behavior, followed by descriptions of what is known about well-studied species. We have taken a holistic approach, focusing not only on the behaviors themselves but also on the factors that constrain the expression of behavior and the proximate mechanisms driving behavior. In many cases, the chapters represent collaborations between well-established researchers and early-mid career individuals who bring new perspectives to help carry the field of phocid behavioral ecology well into the future.
    Type of Medium: Online Resource
    Pages: XVIII, 645 p. 180 illus., 161 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030889234
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    DDC: 577.6
    Language: English
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    Keywords: Neurosciences. ; Neurology . ; Pharmaceutical chemistry. ; Cognitive neuroscience. ; Neuroscience. ; Neurology. ; Pharmaceutics. ; Cognitive Neuroscience.
    Description / Table of Contents: Part I: Basic Science of Cerebellum and Ataxias -- Functional anatomy of the cerebellum -- Cerebellar physiology -- Cerebellar biochemistry/pharmacology -- Genetics of dominant ataxias -- Autosomal and X-linked degenerative ataxias: from genetics to promising therapeutics -- Seeking therapies for Spinocerebellar Ataxia: from gene silencing to systems-based approaches -- Ion Channel Genes and Ataxia -- Part II: Biomarkers and tools of trials -- How to Design a Therapeutic Trial in SCAs -- Therapy development for spinocerebellar ataxia: Rating Scales and Biomarkers -- Clinical rating scales for ataxia -- Scale for Ocular motor Disorders in Ataxia (SODA): Procedures and Basic Understanding -- Cerebellar learning in the prism adaptation task -- Blood and CSF biomarkers in autosomal dominant cerebellar ataxias -- Part III: Autosomal Dominant Cerebellar Ataxias -- Riluzole in progressive cerebellar ataxias -- ASOs against ATXN2 in preclinical and phase 1 trials -- Antisense oligonucleotide therapy against SCA3 -- Spinocerebellar ataxia type 7: From mechanistic pathways to therapeutic opportunities -- Experimental neurotransplantation for cerebellar ataxias -- Development of mesenchymal stem cells therapy for the treatment of polyglutamine SCA: from bench to bedside -- Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia -- Cerebellar Transcranial Magnetic Stimulation in Cerebellar Ataxias -- Physical therapy in Cerebellar Ataxia -- Part IV: Autosomal Recessive Cerebellar Ataxias -- Recent advances on therapeutic approaches for Friedreich’s Ataxia -- Therapeutic use of interferon gamma in Friedreich ataxia -- Metabolic treatments of cerebellar ataxia -- Clinical Trials in Fragile X-Associated Tremor/Ataxia Syndrome -- Part V: Sporadic Ataxias -- Therapeutic strategies in immune-mediated cerebellar ataxias -- Coenzyme Q10 in MSA -- State of the Art and History of Therapeutics in Ataxias.
    Abstract: Despite the critical importance of the cerebellum in brain functions, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.
    Type of Medium: Online Resource
    Pages: XI, 727 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031243455
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Life sciences. ; Physiology. ; Agriculture. ; Biotechnology. ; Life Sciences. ; Animal Physiology. ; Agriculture.
    Description / Table of Contents: Chapter 1: Nutrition and Metabolism: Foundations for Animal Growth, Development, Reproduction, and Health -- Chapter 2: Insights into the Regulation of Implantation and Placentation in Humans, Rodents, Sheep, and Pigs -- Chapter 3: A Role for Fructose Metabolism in Development of Sheep and Pig Conceptuses -- Chapter 4: Nutritional Regulation of Embryonic Survival, Growth and Development -- Chapter 5: Phosphate, Calcium, and Vitamin D: Key Regulators of Fetal and Placental Development in Mammals -- Chapter 6: Nutritional and Physiological Regulation of Water Transport in the Conceptus -- Chapter 7: Amino Acids in Microbial Metabolism and Function -- Chapter 8: Potential Replacements for Antibiotic Growth Promoters in Poultry: Interactions at the Gut Level and their Impact on Host Immunity -- Chapter 9: Microbiomes in the Intestine of Developing Pigs: Implications for Nutrition and Health -- Chapter 10: L-Arginine Nutrition and Metabolism in Ruminants -- Chapter 11: Hepatic Glucose Metabolism and Its Disorders in Fish -- Chapter 12: Protein-Sourced Feedstuffs for Aquatic Animals -- Chapter 13: Functional Molecules of Intestinal Mucosal Products in Animal Nutrition and Health -- Chapter 14: Use of Genome Editing Techniques to Produce Transgenic Farm Animals -- Chapter 15: Cows as Bioreactors for the Production of Nutritionally and Biomedically Significant Proteins -- Chapter 16: Use of Agriculturally Important Animals as Models in Biomedical Research -- Chapter 17: Pigs (Sus Scrofa) in Biomedical Research.
    Abstract: This book covers hot topics in the nutrition and metabolism of terrestrial and aquatic animals, including the interorgan transport and utilization of water, minerals, amino acids, glucose, and fructose; the development of alternatives to in-feed antibiotics for animals (e.g., swine and poultry); and metabolic disorders (or diseases) resulting from nutrient deficiencies. It enables readers to understand the crucial roles of nutrients in the nutrition, growth, development, and health of animals. Such knowledge has important implications for humans. Readers will also learn from well-written chapters about the use of new genome-editing biotechnologies to generate animals (e.g., cows and swine) as bioreactors that can produce large amounts of pharmaceutical proteins and other molecules to improve the health and well-being of humans and other animals, as well as the growth and productivity of farm animals. Furthermore, the book provides useful information on the use of animals (e.g., cattle, swine, sheep, chickens, and fish) as models in biomedical research to prevent and treat human diseases, develop infant formulas, and improve the cardiovascular and metabolic health of offspring with prenatal growth restriction. Editor of this book is an internationally recognized expert in nutrition and metabolisms. He has about 40 years of experience with research and teaching at world-class universities in the subject matters. He has published more than 660 papers in peer-reviewed journals, 90 chapters in books, and authored two text/reference books, with a very high H-index of 127 and more than 66,000 citations in Google Scholar. This publication is a useful reference for nutrition and biomedical professionals, as well as undergraduate and graduate students in animal science, aquaculture, zoology, wildlife, veterinary medicine, biology, biochemistry, food science, nutrition, pharmacology, physiology, toxicology, and other related disciplines. In addition, all chapters provide general and specific references to nutrition and metabolism for researchers and practitioners in animal agriculture (including aquaculture), dietitians, animal and human medicines, and for government policy makers.
    Type of Medium: Online Resource
    Pages: VI, 346 p. 43 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030856861
    Series Statement: Advances in Experimental Medicine and Biology, 1354
    DDC: 660.6
    Language: English
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  • 74
    Keywords: Neurosciences. ; Nervous system Diseases. ; Neurology . ; Neurophysiology. ; Neuropsychology. ; Neurons. ; Neuroscience. ; Neurological Disorders. ; Neurology. ; Neurophysiology. ; Neuropsychology. ; Cellular Neuroscience.
    Description / Table of Contents: Introduction: Neuroglia in psychiatric disorders -- Chapter 1. Astrocytes: The housekeepers and guardians of the CNS -- Chapter 2. Principles of astrogliopathology -- Chapter 3. Morphological appearance of astroglia in neuropsychiatric disorders -- Chapter 4. Astrocytes and neurotransmission: Glutamate and GABA in cognitive and mood disorders -- Chapter 5. Astroglia in bipolar disorder -- Chapter 6. Astroglia abnormalities in mood disorders -- Chapter 7. Astroglia in major depression and suicide -- Chapter 8. Neuroglia in Schizophrenia -- Chapter 9. Glutamate turnover in Schizophrenia -- Chapter 10. Astroglia and dopanime transmission in Schizophrenia -- Chapter 11. Kynurenic acid in Schyzophrenia -- Chapter 12. Astrocytes in addictive disorders -- Chapter 13. Astroglia in the vulnerability and maintenance of alcohol dependence -- Chapter 14. Astroglia in response to stress -- Chapter 15. Astroglia and Obsessive compulsive disorder -- Chapter 16. Astrocytes in regulation of food intake -- Chapter 17. Astrocytes in anorexia nervosa -- Chapter 18. Astroglial serotonin receptors as the central target of classic antidepressants -- Chapter 19. Lithium targets astrocytes -- Epilogue.
    Abstract: This contributed volume discusses the multiple roles of astrocytes, which determine the progression and outcome of neuropsychiatric diseases. This emerging area of study examines the ways in which astrocytes are involved in various aspects of disease initiation, progression and resolution. This monograph aims to integrate the body of information that has accumulated in recent years revealing the active role of astrocytes in neuropsychiatric pathology and in psychiatric disorders. Understanding roles of astrocytes in pathology will provide new targets for medical intervention and aid the development of much needed therapeutics. This book will be valuable for researchers and workers in the fields of neurobiology, neurology, and psychiatry, as well as fill the need for a textbook used in advanced courses/graduate seminars in glial pathophysiology.
    Type of Medium: Online Resource
    Pages: VI, 377 p. 36 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030773755
    Series Statement: Advances in Neurobiology, 26
    DDC: 612.8
    Language: English
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  • 75
    Keywords: Freshwater ecology. ; Marine ecology. ; Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Freshwater and Marine Ecology. ; Microbiology. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: 1. Marine Biotechnology: A Frontier for the Discovery of Nutraceuticals, Energy, and Its Role in Meeting 21st Century Food Demands -- 2. Biotechnological Utilization of the Marine Environment for Food, Drugs and Energy -- 3. Grouper Hybridization: An Effective Biotechnological Tool for Food Security -- 4. The Application of Molecular Markers to Fish Breeding and Aquaculture -- 5. Aquaculture and Applications of Green Seaweeds of the Genus Caulerpa J.V. Lamouroux, 1809 -- 6. Potential and Challenges of Sea Cucumber Holothuria Scabra Mariculture in Sabah, Malaysia -- 7. Sea Cucumber (Echinodermata: Holothuroidea) Species Diversity on the West Coast of Sabah, Malaysia -- 8. Sea Cucumbers: Source of Nutritional, Medicinal, and Cosmeceutical Products -- 9. Marine Biotechnology and its Applications in Drug Discovery -- 10. Bacteriophage as Therapeutic Strategy Against Pathogenic Vibrio -- 11. Bacterial Diversity in the Marine Environment and the Cutting-edge Tools for Isolation, Identification, and Characterization of the Marine Microbiome -- 12. Biotechnological Applications of Jellyfish-Derived Products -- 13. Application of Biotechnology in White Syndrome Coral Disease Identification -- 14. The Synergy of Remote Sensing in Marine Invasion Science -- 15. The Utilization of Agro-based Wastes by Marine Phototrophic Microbes -- 16. Artificial Intelligence Methods in Marine Biotechnology.
    Abstract: This contributed volume covers the applications of marine biotechnology for food, drugs and energy production using marine resources. It introduces many aspects of marine biotechnology, including bioenergy, pharmaceutical development, food security from mariculture, pollution handling, legal issues and conflicts. Information in the book is accompanied by clear images, flow charts, quantitative and qualitative data. Marine biotechnology is essential for realizing the previously untapped potential of marine bio-resources. These resources are used to develop innovative goods and procedures that aid in the global management of food, energy, and disease management. The development of innovative tools and solutions for more sustainable marine environmental management is another important section of this title. This reference book is of interest to teachers, researchers, and climate change scientists. It serves as an additional reading material for college, undergraduate, and graduate students of marine science and aquaculture. This is also a good research guide for food and fishing industry scientists.
    Type of Medium: Online Resource
    Pages: XIII, 354 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819906246
    DDC: 577.6
    Language: English
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  • 76
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Neurology . ; Neuroscience. ; Neuropsychology. ; Neurology.
    Description / Table of Contents: Chapter 1: Understanding the Mechanisms of Dendritic Arbor Development: Integrated Experimental and Computational Approaches -- Chapter 2: Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive -- Chapter 3: Environmental enrichment and functional plasticity in the hippocampus, an update on the mechanisms involved -- Chapter 4: Translatable Models of Brain and Cognitive Reserve -- Chapter 5: Cognitive Reserve: A Life-Course Perspective -- Chapter 6: Neural Correlates of Brain Reserve: A Neuroimaging Perspective -- Chapter 7: Non-pharmacological Approaches Based on Mind-Body Medicine to Enhancement of Cognitive and Brain Reserve in Humans -- Chapter 8: Roles of Synaptic Plasticity in Functional Recovery After Brain Injury -- Chapter 9: Integrated Methods of Neuromodulation for Guiding Recovery Following Stroke -- Chapter 10: Resilience in Brain Networks After Stroke -- Chapter 11: Epigenetics and brain plasticity: back to function -- Chapter 12: Functional Role of Physical Exercise and Omega-3 Fatty Acids on Depression and Mood Disorders -- Chapter 13: BRAIN RECOVERY IN CHILDHOOD: THE INTERACTION BETWEEN DEVELOPMENTAL PLASTICITY AND REGENERATIVE MECHANISMS -- Chapter 14: Estrogen Neuroprotective Activity After Stroke and Spinal Cord Injury -- Chapter 15: Making Meaning of Acquired Brain Injury: Resources for Functional Recovery -- Chapter 16: An Update on Premorbid Personality Traits and Brain Recovery - Another Aspect of Resilience -- Chapter 17: Psychological Aspects of Recovery After Brain Injury: A Focus on Psychodynamic Factors -- Chapter 18: Artificial Intelligence applications for Traumatic Brain Injury research and clinical management.
    Abstract: The importance of this unique book's approach lies in addressing the impact of neurobiological factors as well as psychological influences on brain recovery following injury. There is growing evidence that emotional, motivational, and cognitive factors along with personality traits play a crucial role in brain plasticity, resilience, and recovery. Topics include synaptic and neuronal plasticity, development of brain reserves, biological markers, environmental factors, emotional resilience, and personality traits. By combining the latest research on neural mechanisms and psychological resilience the authors present a book that will help lead to the development of better treatment strategies for functional recovery from brain damage. The new edition is fully updated throughout and contains completely new chapters on brain recovery in childhood, epigenetic aspects of brain recovery, and artificial intelligence techniques in traumatic brain injury research.
    Type of Medium: Online Resource
    Pages: XXIV, 406 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031249303
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 77
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Animal biotechnology. ; Physiology. ; Freshwater ecology. ; Marine ecology. ; Animal Biotechnology. ; Animal Physiology. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Chapter 1. Biotechnological Approaches in Fish Health Management -- Chapter 2. RNA Interference and Its Potential Applications in Aquatic Animal Health Management -- Chapter 3. Biotechnological Advances in the Development of Outer Membrane Protein-Based Vaccines for Use in Aquaculture -- Chapter 4. Application Of Carbon Nanotubes In Advancement Of Fish Vaccine -- Chapter 5. Biotechnological Interventions In Developing Vaccines Against Aeromonas Infection In Aquaculture -- Chapter 6. Gene Editing Technology For Fish Health Management -- Chapter 7. Applications of Fish Cell Cultures -- Chapter 8. Recent Advances In Antimicrobial Peptides To Improve Fish Health -- Chapter 9. Gut Microbiome Research: A New Avenue For Aquaculture Disease Management. Chapter 10. Recent Understanding of Immunological Defence in Freshwater Pearl Mussel for Better Health Management -- Chapter 11. Prebiotic-Synbiotic Nexus: Critical Dietary Role in Aquaculture -- Chapter 12. Biofloc Technology: An Eco-Based Emerging Avenue In Aquaculture Health Management -- Chapter 13. Metabolomic Advances in Fish Nutritional Research and Health Management -- Chapter 14. Vaccines to Prevent Diseases in Aquaculture -- Chapter 15. A Progress on Biotechnological Advances on Immunostimulants and Gene Interaction -- Chapter 16. Probiotic Supplements in Aquaculture: Latest Developments & Future Trend -- Chapter 17. Heat Shock Proteins (Chaperones) and Role in Aquatic Animal Disease Management -- Chapter 18. Nanotechnology in Fish Health and Welfare: Recent Advancements and New Perspectives -- Chapter 19. Advances in Management Methods for Argulosis in Aquaculture -- Chapter 20. Metagenomic Approaches to Identify Fish Gut Microbiome and The Effect of Prebiotic Supplements on Gut Microbes and Health Management -- Chapter 21. Microbiome Interventions for The Prevention and Control of Disease Outbreaks in Shrimp Aquaculture. Chapter 22. Reinventing the Micronutrients Beyond Nutrition: Functions in Immune Modulation and Stress Mitigation of Fish -- Chapter 23. Health-Promoting Effects of Amino Acids in Fish -- Chapter 24. Application of Indian Pennywort Centella Asiatica in Carp Aquaculture Against Flavobacterium Columnare Infection.
    Abstract: This book is an inclusive coverage of advances in aquaculture health management. It offers latest updates as well as explains the novel concepts and issues related to aquatic animal health management. To support the understanding of the concepts, there is extensive use of illustrations. Chapters emphasize on the state of art techniques and hold great promise for the sustainable development of aquaculture. This book is of interest to teachers, researchers, aquatic biologists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of aquatic sciences, marine sciences, biotechnology, ecology, and environmental sciences. National and international aquatic scientists, policy makers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XXIV, 579 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811651953
    DDC: 660.6
    Language: English
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  • 78
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. The Auditory Cognitive Neuroscience of Speech Perception in Context -- 2. Subcortical Processing of Speech Sounds -- 3. Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology -- 4. A Parsimonious Look at Neural Oscillations in Speech Perception -- 5. Extracting Language Content From Speech Sounds: The Information Theoretic Approach -- 6. Speech Perception under Adverse Listening Conditions -- 7. Adaptive Plasticity in Perceiving Speech Sounds -- 8. Development of Speech Perception -- 9. Interactions Between Audition and Cognition in Hearing Loss and Aging.
    Abstract: This volume reviews contemporary developments in the auditory cognitive neuroscience of speech perception, including both behavioral and neural contributions. It serves as an important update on the current state of research in speech perception. The Auditory Cognitive Neuroscience of Speech Perception in Context Lori L. Holt, and Jonathan E. Peelle Subcortical Processing of Speech Sounds Bharath Chandrasekaran, Rachel Tessmer, and G. Nike Gnanateja Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology Yulia Oganian, Neal P. Fox, and Edward F. Chang A Parsimonious Look at Neural Oscillations in Speech Perception Sarah Tune, and Jonas Obleser Extracting Language Content From Speech Sounds: The Information Theoretic Approach Laura Gwilliams, and Matthew H. Davis Speech Perception under Adverse Listening Conditions Stephen C. Van Hedger, and Ingrid S. Johnsrude Adaptive Plasticity in Perceiving Speech Sounds Shruti Ullas, Milene Bonte, Elia Formisano, and Jean Vroomen Development of Speech Perception Judit Gervain Interactions Between Audition and Cognition in Hearing Loss and Aging Chad S. Rogers, and Jonathan E. Peelle .
    Type of Medium: Online Resource
    Pages: XVI, 252 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030815424
    Series Statement: Springer Handbook of Auditory Research, 74
    DDC: 612.8
    Language: English
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  • 79
    Keywords: Neurosciences. ; Anatomy. ; Internal medicine. ; Neuroscience. ; Anatomy. ; Internal Medicine.
    Description / Table of Contents: PART I. Glial-Neuronal Interactions in the Control of Hypothalamic Development -- The Role of Microglia in the Developing Hypothalamus -- PART II. Glial-Neuronal Interactions in the Control of the Magnocellular Neuroendocrine System -- Functional Consequences of Morphological Plasticity in the Adult Hypothalamo-Neurohypophysial System -- Fenestrated Capillary and Dynamic Neuro-Glial-Vascula Reorganization of the Adult Neurohypophysis -- Astrocyte-Magnocellular Neuron Interactions in Hypothalamic Memory -- The Multifaceted Roles of Hypothalamic Astrocytes and Microglial Cells in Neuroendocrine and Autonomic Regulation in Health and Disease -- PART III. Gial-Neuronal Interactions in the Control of Metabolic Function -- Control of Systemic Metabolism by Astrocytes in the Brain -- Glia-Neuron Communication: Not a One-way Street -- PART IV. Glial-Neuronal Interactions in the Control of the Stress Response -- Retrograde Signaling Via Dendritic Activation of Glial-Neuronal Circuits -- PART V. Glial-Neuronal Interactions in the Control of Reproductive Function -- Microglia, Hormones, and Behavior -- Hypothalamic Astrocytes and the Role of Neuroprogesterone in Estrogen Positive Feedback -- PART VI. Glial-Neuronal Interactions that Link Brain and Periphery -- Unveiling the Importance of Tanycytes in the Control of the Dialogue Between the Brain and the Periphery -- Tanycyte Regulation of Hypophysiotropic TRH Neurons.
    Abstract: This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today. Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication. Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems. This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 324 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030623838
    Series Statement: Masterclass in Neuroendocrinology, 11
    DDC: 612.8
    Language: English
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  • 80
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biotic communities. ; Landscape ecology. ; Water. ; Hydrology. ; Biodiversity. ; Conservation biology. ; Ecology . ; Freshwater and Marine Ecology. ; Ecosystems. ; Landscape Ecology. ; Water. ; Biodiversity. ; Conservation Biology.
    Description / Table of Contents: Introduction -- Part I. Historical Perspectives -- Vertebrates of Upper Mesopotamia: Present Evidence and Archaeological Data -- Fishing Gears and Methods: A Comparison of Ancient Mesopotamia and Other Ancient Worlds -- Ichthyological Characteristics Available in the Fish Images Existed in the Art of the Ancient Mesopotamia -- The Effectiveness of Ancient Mesopotamian Medical Practices: The Example of šūšu-Licorice -- Part II. The Abiotic Aspects of the Tigris–Euphrates River System -- Management of Water Resources Using Storage Reservoirs -- Estimation of Irrigated Agricultural Area and Water Consumption in Iraq -- The Nature of Tigris–Euphrates Rivers Flow: Current Status and Future Prospective -- Streamflow Alteration Impacts with Particular Reference to the Lower Zab River, Tributary of the Tigris River -- Ecohydrology in Iraq: Challenges and its Future Pathways -- Oil Pollution in the Shatt Al-Arab River and its Estuary 1980–2018 -- Pesticides in the Waters, Sediments, and Biota of the Shatt Al-Arab River for the Period 1980–2017 -- Surface Water Salinity of the Euphrates, Tigris, and Shatt al-Arab Rivers -- Renewable Energy for Water–Energy Nexus in Euphrates and Tigris River Basin: A Literature Review -- Impacts of Dams on Aquatic Biodiversity, Fisheries, Fishes and Their Environment: Problems that Could Be Present in Iraq with Recommendations -- Water, Politics and Dams in the Mesopotamia Basin of the Northern Middle East: How Turkey Instrumentalises the South-Eastern Anatolia Project for Political, Military and Strategic Interests -- Dams and their Impacts on Fishes in Iran -- Part III. The Biotic Aspects of the Tigris–Euphrates River System -- Preliminary Review of the Aquatic Biodiversity in Al-Kahla River, Missan Province, Iraq -- Freshwater Fish Biodiversity in Iraq: Importance, Threats, Status, and Conservation Challenges -- Effect of Climate Changes on the Freshwater Biodiversity in the Mesopotamian Plain: Recommendations for Avoidance and Plans for the Future -- River Corridors as a Refuge for Freshwater Biodiversity: Basic Information and Recommendations to the Policymakers for Possible Implications in Iraq -- Biodiversity of Fungi in Aquatic Environment of Iraq -- Potability of Drinking Water in Basra-Iraq -- Algal Studies in Iraqi Inland Waters. A Review -- The Distribution of Epilitic Diatoms in the Turkish Part of the Tigris-Euphrates River Basin -- Plant Biodiversity in Shatt Al-Arab Estuary and Ecological Variations -- Medicinal Plants of Shatt al-Arab River and Adjacent Area -- The Role of Plants as a Canopy in the Inland Waters: Basic Information for Application in Iraq -- The Zooplankton Fauna of the Turkish Part of the Euphrates-Tigris River Basin -- Kinds and Distribution of Icthyoplankton in Shatt Al-Arab River -- Rotifer Diversity in Iranian Waters: A Review -- Biodiversity of the Freshwater Amphipods in Iran -- The Freshwater Molluscs of the Mesopotamian Plain -- Freshwater Annelida of Iraq -- A Critical Checklist of the Inland Fishes Native to the Euphrates and Tigris Drainages -- Fish Fauna of Shatt al-Arab River, Basrah, Iraq: A More than Quarter a Century of Changes -- The Common Carp, Cyprinus carpio: Effect on the Environment and the Indigenous Fish Species in Iraq -- The Good and the Bad in Releasing the Grass Carp Ctenopharyngodon idella in the Freshwater System: Recommendations for the Policymakers in Iraq -- The Avifauna of Tigris and Euphrates River Basin -- The Feasible Approaches to Assist Migratory Birds Visiting the Southern Reaches of Mesopotamia -- A Proposal for Establishing Bird Observatory Centre in the South of Iraq -- The Potential Role of Waterbirds as a Vector in Dispersing Invertebrates and Plants in the South of Iraq -- The Wild Mammals of the Tigris and Euphrates Rivers Basin -- The Amphibians and Reptiles of Euphrates and Tigris Basin -- A Preliminary Pictorial Guide to the Herpetofauna of Tigris and Euphrates River Basin -- Policy Guidance for Sustainable Aquaculture in the Inland Waters of Iraq -- How Possible to Use the Desert Area in Iraq for Aquaculture Industry: Basic Facts and Recommondations -- Aquaculture Industry in Iraq: Past, Present, and Future Perspectives -- Towards an Improved Tilapia Farming in Iraq: Recommendations for Future Application -- Information and Recommendations of Aquaculture Stress and its Source in Hatcheries: The Iraqi Aquaculture Industry Investors -- Exotic and Invasive Freshwater Fishes in the Tigris-Euphrates River System -- Part IV. Water Resources -- The Ecology and Modelling of the Freshwater Ecosystems in Iran -- Enhancing Rural Women’s Participation in Fisheries in Iraq -- The Impact of Destructive Fishing Gear on the Fish Biodiversity in the Inland Waters of Iraq -- Evaluating Variations in Fisheries by Means of Fishers’ Information: Suggested Methodology to Improve Small-Scale Fisheries in Rivers in Iraq -- A Possibility to Apply a Traditional Fisheries Enforcement Programme in the Inland Waters of Iraq -- Market-Resource Relations and Fish Seller Livelihood as Seen in Inland Waters of Iraq -- The Potential Impact of Deformities in Fishes upon Aquatic Production: Case of Iraq -- The Impact of some Social Taboos on Fisheries in Iraq -- Inland Water Fishes and Fisheries in Iran -- The Possibility of Introducing an Inland Fisheries Education in Iraq -- The Marine and Diadromous Fisheries of Iraq -- Part V. Stress of the Environment of the Two Rivers -- Fish Deformities in the Freshwater Fishes of Iraq: A Short Review and a Study Case on the Indian Catfish Heteropneustes fossilis -- The Phenomenon of Fluctuating Asymmetry: As Fish Welfare Indicator Represented by Case Study from the Freshwater Fishes of Iraq -- The Studies on Sediments Pollution by Different Types of Metals in Turkey -- Macroplastic and Microplastic in the Freshwater Environment of Southern Iraq: Evidences Obtained from Freshwater Fish Species -- Heavy Metals in Freshwater Invertebrates of Iran: A Review on the Bioaccumulation and Effects -- Fish Parasites of Tigris and Euphrates River Systems -- The Parasites of Fishes of the Euphrates and Tigris Rivers: Iraq and Turkey -- Ornamental Fishes: A Looming Danger for Inland Fish Diversity of Iraq -- Part VI. The Health of the Human Community Inhabiting Freshwater Zones -- Aquatic Snails as a Vector of Diseases to the Human in Iran -- Death by Drowning in Rivers in Iraq -- The Dangerous Catfish Species in the Freshwater System of Iraq: First Time Reports on Cases of Envenomation -- Fish Species of the Order Cypriniformes as a Source of Ichthyootoxin and Ichthyogallotoxin in Iraq: Cases Reports -- First Reports on Cases of Hallucinatory Fish Poisoning (Ichthyoallyeinotoxism) and Scombrotoxic Fish Poisoning in Iraq -- Part. VII. Conservation -- Freshwater Management and Conservation in Iran: Past, Present, and Future -- The Need of Biodiversity Conservation Strategies in Iraq: The State of Protected Areas -- Benthic Macroinvertebrates of the Tigris and Euphrates Rivers in Turkey -- Freshwater Ecosystem Conservation in Iraq: Recommendations for Management -- Utilising Phenotypic Difference to Regulate Protection Value: A Scheme for Application of a Novel Approach to the Inland Water of Iraq -- Hatchery-Reared Fish Stocks Released into the Wild: A Conservation Problem as Seen in a Case Study from Iraq -- Part VIII. Social Perspectives -- Is the Glass Half Empty or Half Full? An Appraisal of the Four Decades of Turkey’s Southeastern Anatolia Project (GAP) -- Part IX. Food Security -- How Possible to Build Rice–Fish Farming in Iraq in order to Support Food Security Plan: Positive and the Negative Aspects -- The Importance of Non-commercial and Small-Sized Fish Species: A Proposal for an Additional Revenue to Iraq -- Sociocultural Aspects Influence Food Consumption Habits in Iraq: Management of Food Security -- A Preliminary Investigation of Determinants of Food Security in Rural Areas of Basrah Province, Iraq.
    Abstract: The system of the Tigris-Euphrates Rivers is one of the great river systems of southwestern Asia. It comprises the Tigris and Euphrates Rivers, which follow roughly parallel courses through the heart of the Middle East. The lower portion of the region that they run through is known as Mesopotamia, was one of the cradles of civilisation. There are several environmental factors that govern the nature of the two rivers and shape the landscape the two rivers running through. Geological events create rivers, climate monitor the water supply, the surrounding land influences the vegetation and the physical and chemical features of water. The Tigris-Euphrates system runs through the territory of four countries, Iraq, Iran, Turkey and Syria. Therefore, any scientific approach to the environment of these two rivers should include the natural history events in these countries. The book "Tigris and Euphrates Rivers: Their Environment from Headwaters to Mouth" will be divided into nine parts. These parts deal with the issues of the environment, the status of the flora and fauna, the abiotic aspects, ecology, hydrological regime of the two rivers, the biotic aspects, water resources, stress of the environment, conservation issues. Since the book of Julian Rzoska "Euphrates and Tigris Mesopotamian Ecology and Destiny" in 1980, no book or major reference has been published that includes between its cover the facts and information that the present book will present. Therefore, the importance of the present book falls in stating the present status of the environment of the two rivers and the comparison of their environment between now and that of 37 years ago as given by J. Rzoska (1980). The recent studies showed that there are a large number of natural and political events that happened within the last three decades in the area of the Tigris-Euphrates river system that for sure have done a great change to the environment of the two rivers and consequently changing the biological and non-biological resources of the two rivers. This book will be a reference book to both academic researchers and students across the Middle East in different disciplines of knowledge to use in their researches on Tigris-Euphrates river system. The scholars interested in this area will use this book as a guide to compare this freshwater system with other areas in Asia and the world. .
    Type of Medium: Online Resource
    Pages: XXIII, 1640 p. 387 illus., 317 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030575700
    Series Statement: Aquatic Ecology Series, 11
    DDC: 577.6
    Language: English
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  • 81
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Zoology. ; Neurochemistry. ; Neuroscience. ; Zoology. ; Neurochemistry.
    Description / Table of Contents: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.
    Abstract: This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.
    Type of Medium: Online Resource
    Pages: XII, 501 p. 96 illus., 73 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031123900
    Series Statement: Advances in Neurobiology, 29
    DDC: 612.8
    Language: English
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  • 82
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Behavioral Neuroscience.
    Description / Table of Contents: Part I Preclinical Research: Neuroendocrine Mechanisms of Social Bonds and Separation Stress in Rodents, Dogs, and Other Species -- Methods and Challenges in Investigating Sex-Specific Consequences of Social Stressors in Adolescence in Rats: Is It the Stress or the Social or the Stage of Development?- Social stress-induced neuroinflammation and mitochondrial dysfunction as a link to depression and cardiovascular disease comorbidity -- Mean Girls: Social Stress Models for Female Rodents -- Development of Mixed Anxiety/ Depression-Like State as a Consequence of Chronic Anxiety: Review of Experimental Data -- Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse -- Social Stress and Aggression in Murine Models -- More or less: glucocorticoid roles in aggression -- Neurobiological Bases of Urges for Alcohol Consumption After Social Stress -- Epigenetics of Aggression -- Part II Human Research: Early Life Stress and Neurodevelopment in Adolescence: Implications for Risk and Adaptation -- Effects of Parenting Environment on Child and Adolescent Social-Emotional Brain Function -- The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans -- Social Acts and Anticipation of Social Feedback -- Clinical Outcomes of Severe Forms of Early Social Stress -- Childhood Violence Exposure, Inflammation, and Cardiometabolic Health -- Social Support Effects on Neural Stress and Alcohol Reward Responses -- Neural Underpinnings of Social Stress in Human Addiction.
    Abstract: Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
    Type of Medium: Online Resource
    Pages: VIII, 515 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031042560
    Series Statement: Current Topics in Behavioral Neurosciences, 54
    DDC: 612.8
    Language: English
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  • 83
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Psychiatry. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Section I. Anhedonia – History, Etiology, and Assessments -- 1. Historical Perspective -- 2. Clinical and Behavioral Assessments -- 3. Developmental Trajectories: Preclinical -- 4. Developmental Trajectories: Clinical -- 5. Genetics Contributions -- 6. Environmental Contributions -- Section II. Anhedonia in Psychiatric and Neurological Disorders -- 7. Depression and Bipolar Disorder -- 8. Schizophrenia -- 9. Substance Use Disorder -- 10. Nicotine Dependence -- 11. Posttraumatic Stress Disorder -- 12. Anxiety -- 13. Eating Disorders -- 14. Autism and Developmental Disorders -- 15. Neurodegenerative Disorders -- Section III. Reward Processing Systems in Anhedonia -- Reward Responsiveness -- 16. Pleasure -- 17. Anticipation -- Reward Valuation -- 18. Reward Value – Delay and Reward Magnitude -- 19. Effort/Motivation -- Reward Learning -- 20. Reward Prediction Error -- 21. Probabilistic and Reinforcement Learning -- Section IV. Treatments -- 22. Pharmacological Treatments for Anhedonia -- 23. Psychological Treatments for Anhedonia -- 24. Neurostimulation -- Section V. Special Topics -- 25. Inflammation and Anhedonia -- 26. Computational Modeling of Anhedonia -- 27. Anhedonia and Suicide.
    Abstract: Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.
    Type of Medium: Online Resource
    Pages: XI, 535 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031096839
    Series Statement: Current Topics in Behavioral Neurosciences, 58
    DDC: 612.8
    Language: English
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  • 84
    Keywords: Neurosciences. ; Neurophysiology. ; Developmental neurobiology. ; Neuroscience. ; Neurophysiology. ; Development of the Nervous System.
    Description / Table of Contents: Chapter 1: Introduction: What are dendritic spines? -- Chapter 2: Techniques to render dendritic spines visible in the microscope -- Chapter 3: Electrophysiology of dendritic spines: information processing, dynamic compartmentalization and synaptic plasticity -- Chapter 4: Dendritic spines, synaptogenesis and synaptic pruning for the developmental organization of brain circuits -- Chapter 5: Neurotrophic factors and dendritic spines -- Chapter 6: Glial cell modulation of dendritic spine structure and synaptic function -- Chapter 7: Dendritic spines in learning and memory: from first discoveries to current insights -- Chapter 8: Steroid hormone interaction with dendritic spines: implications for neuropsychiatric disease -- Chapter 9: Morphological features of human dendritic spines.
    Abstract: This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.
    Type of Medium: Online Resource
    Pages: XV, 499 p. 123 illus., 103 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031361593
    Series Statement: Advances in Neurobiology, 34
    DDC: 612.8
    Language: English
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  • 85
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Clinical psychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Clinical Psychology. ; Psychiatry.
    Description / Table of Contents: Preface -- PART 1: To fear or not -- Disambiguating fear as an emotional state vs. threat detection. Molecular and Neural circuits of fear extinction. Psychological and theoretical elements on the concept of fear extinction. Neural circuit of fear extinction: psychophysiology -- PART 2: Individual differences in fear extinction -- The impact of sex differences and sex hormones on fear extinction. Impact of sleep on fear extinction. Impact of stress and exercise on fear extinction. Intersect between the intrinsic and extrinsic factors that modulate fear extinction -- PART 3: Psychopathology -- Fear extinction and its relevance to psychopathology. Developmental fear and its extinction imaging. Fear extinction and adult psychopathology -- Part 4: Therapeutics and neuromodulations of fear extinction -- Exposure therapy and other behavioral therapeutics targeting fear extinction circuits. Novel pharmacotherapeutics targeting fear extinction circuits. Reconsolidation and its link and impact on fear extinction. Technological advances in exposure therapy: virtual and augmented reality. Novel approaches using neurostimulation targeting fear extinction.
    Abstract: This book aims to provide the reader a neuroscientific understanding surrounding a very simple question: how do we learn not to fear? Exploring answers to this question is very important for two reasons. First, learning about the neural mechanisms of fear extinction is of relevance to everyone’s life - it is such a basic yet relevant question to our daily experiences. Therefore, understanding brain mechanisms of fear and its regulation is essential from a basic neuroscience point of view. Second, excessive fear and the inability to regulate its expression is one of the hallmarks of fear-, anxiety-, trauma-, and stressor-related psychopathologies. And as such, learning about how fear is acquired, stored, expressed, and regulated could help advance our understanding of the etiology of psychopathology, the maintenance of symptoms pertaining to failure to regulate fear, and could help us develop novel therapeutics to equip providers and patients with the tools to better quell their fears. The contributions contained in this book are provided by experts in the fields of basic and clinical neuroscience, experimental and clinical psychology, and neuropsychiatry. The contributions are organized to start the reader with basic definitions of how we define fear, how we study its neural circuits at the molecular and cellular levels, how to study human behavior and the brain using state-of-the art experimental and statistical tools, to how much fear contributes to psychopathology. This volume ends with current advances aimed to enhance the capacity to extinguish fear; a clinical result that would aid in the treatment of multiple psychiatric disorders, followed by a discussion on future directions of this highly important and relevant field.
    Type of Medium: Online Resource
    Pages: VIII, 387 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031430053
    Series Statement: Current Topics in Behavioral Neurosciences, 64
    DDC: 612.8
    Language: English
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  • 86
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Freshwater ecology. ; Marine ecology. ; Animal culture. ; Biotechnology. ; Animal biotechnology. ; Freshwater and Marine Ecology. ; Animal Science. ; Biotechnology. ; Animal Biotechnology.
    Description / Table of Contents: Chapter 1_ Recent developments in Biosensor Technology for Fisheries and Aquaculture -- Chapter 2_Application of CRISPR-Cas9 Technology in Fish -- Chapter 3_ Nano-technological applications in Aquatic Health Management -- Chapter 4_Phenotypic plasticity and transgenerational immune priming: opportunities and potential in fisheries -- Chapter 5_Heat shock proteins in stress response: a promising tool for fish health management -- Chapter 6_Immunostimulants: Boon for disease management in Aquaculture -- Chapter 7_Molecular markers and their application in fisheries and aquaculture -- Chapter 8_Applications of Electronics in Fisheries and Aquaculture -- Chapter 9_Metatranscriptomics: A tool to study the host-microbe interactions and functional profile of fish intestinal microbiota under changing environmental conditions -- Chapter 10_Bioremediation and its application in aquaculture -- Chapter 11_Application of Probiotics in Aquaculture -- Chapter 12_Identifying novel antibiotic resistance genes (ARGs): Important aspect of metagenomic research.
    Abstract: This edited book is focused on SDG 14: life below water. This book covers all aspects of fish biotechnology and health management. A detailed description is provided of CRISPR Cas9 technology application in the development of superior variety of fish with better growth, disease resistance, etc., accompanied by numerous helpful photographs and schematic diagrams. In addition, recent developments in nanotechnology and its application in fisheries production enhancement have been discussed. Further, topics includes, probiotics, immunostimulants, fish genetic markers, bioremediation, metagenomics, transgenerational immune priming, application of cell culture in fisheries and nano-biosensor application on fish disease diagnosis, pollution monitoring, etc. are provided in details. . The book is helpful for researchers, teachers, students, farmers, and entrepreneurs in utilizing the knowledge on recent advancements in different aspects of fish genetics and biotechnology for future research and aquaculture production enhancement.
    Type of Medium: Online Resource
    Pages: XVIII, 246 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819929818
    DDC: 577.6
    Language: English
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  • 87
    Keywords: Freshwater ecology. ; Marine ecology. ; Ecology . ; Biodiversity. ; Freshwater and Marine Ecology. ; Ecology. ; Biodiversity.
    Description / Table of Contents: Chapter 1_ An Introduction to the Functions and Ecosystems Services associated with aquatic macrophytes -- Chapter 2_ Factors structuring Aquatic Macrophytes -- Chapter 3_ Aquatic Macrophytes: Ecology, Function and Services in Niger Delta, Nigeria -- Chapter 4_ Environmental and Ecological Importance of Indian Aquatic Macrophytes -- Chapter 5_ Macrophytes used as complementary medicines for curing human ailments to facilitate livelihood opportunities -- Chapter 6_ Macrophytes and their role in wetland ecosystems -- Chapter 7_ Ecotoxicology of REEs in aquatic macrophytes and prospect for bioremediation of REEs -- Chapter 8_ Efficiency of Aquatic Plants for Remediation of Wastewater -- Chapter 9_ Phytoremediation of organic contaminants: An ecofriendly approach based application of aquatic macrophytes -- Chapter 10_ Remediation of heavy metals by different aquatic macrophytes -- Chapter 11_ Translocations of heavy metals in aquatic macrophytes naturally grown in the riverine ecosystem -- Chapter 12_ Enhanced Effluent Treatment and Bioelectricity Generation Using Coupled Constructed Wetland-Microbial Fuel Cell (CW-MFC) Technology: Challenges and Opportunities -- Chapter 13_ Role of microbial communities and aquatic macrophytes in constructed wetlands for tannery wastewater treatment: Challenges and opportunities -- Chapter 14_ Role of plant-bacteria association in constructed wetlands for the removal of iron (Fe) from contaminated water. .
    Abstract: This book is a comprehensive collection of information about the features, functions, and services of aquatic macrophytes. As primary producers, aquatic macrophytes form the basis of food webs, play a major role in highly productive aquatic ecosystems, and have a significant impact on ecosystem functions and services. Macrophytes are also known to strongly influence the micro-climate and biogeochemical processes occurring in the littoral zones of marine ecosystems and the sediment dynamics of freshwater systems. They also serve as highly effective carbon sinks and play an important role in carbon sequestration. This book deals with various aspects of aquatic macrophytes, including nutrient recycling, biogeochemical processes, biomass production, wetland ecosystems, water resource management, carbon sequestration, environmental clean-up, and bioenergy production. Additionally, it presents the current status of aquatic macrophytes and discusses the impact of climate change on these plants. The book also highlights the major challenges associated with harnessing the benefits provided by aquatic macrophytes as ecosystem services. The book holds value and relevance for academicians and scientists working in the related domain. Additionally, it will serve as a valuable resource for students and researchers working in the field of ecology, biogeochemistry, wetland conservation, phytoremediation, elements biomonitoring, wastewater management, bioenergy production, etc.
    Type of Medium: Online Resource
    Pages: X, 311 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938223
    DDC: 577.6
    Language: English
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  • 88
    Keywords: Biotechnology. ; Molecular biology. ; Agriculture. ; Biotechnology. ; Molecular Biology. ; Agriculture.
    Description / Table of Contents: 1. Bioenergy Crops in the Perspective of Climate Change -- 2. Major and Potential Biofuel Crops -- 3. Biotechnological approaches for the production of Bioenergy -- 4. Integrated OMIC approaches for bioenergy crops -- 5. Genomics of Bioenergy Crops -- 6. Omics Approaches for Sorghum: Paving the Way to a Resilient and Sustainable Bioenergy Future -- 7. Exploring Omics Approaches to Enhance Stress Tolerance in Soybean for Sustainable Bioenergy Production -- 8. Advanced and Sustainable Approaches in Sugarcane Crop Improvements with Reference to Environmental Stresses -- 9. Role of endophytes in the regulation of metabolome in bioenergy crops -- 10. Cotton Stalks - Potential Biofuel Recourses for Sustainable Environment -- 11. Harmful Insects in Some Biofuel Plants and Their Biology -- 12. Perspectives use of mustards in biofuel production in Turkey -- 13. Current status and future prospectus of Bioenergy crops.
    Abstract: This edited book summarizes the efforts made to develop sustainable bioenergy production through different generations. The topics included in the book cover information about different bioenergy crops, their classification and use as biofuel, agronomic practices to improve biomass yield, classic breeding techniques, genetic diversity, current status and future perspective of bioenergy crops in the omics era. It also discusses application of modern biotechnological and molecular biotechnological techniques for the improvement of bioenergy crops this having enhanced biomass and plant based products. The book explores growing biofuel crops and their impact on environment, bioethics and biosafety issues related to the modern approaches. Another important aspect is the incorporation of nanotechnology for bioenergy crops and biofuel production. All book chapters are contributed renowned researchers in their respective field. This is a unique book covering the bioeneragy crops in the modern omics era. The book is useful for the researchers and post-graduate students to guide them in the field of bioenergy crops.
    Type of Medium: Online Resource
    Pages: XV, 288 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819949540
    DDC: 660.6
    Language: English
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  • 89
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Zoology. ; Ecology . ; Oceanography. ; Conservation biology. ; Freshwater and Marine Ecology. ; Biodiversity. ; Zoology. ; Biooceanography. ; Conservation Biology.
    Description / Table of Contents: Part I. Introduction -- Chapter 1. Insights from Cuban Coral Reefs -- Part II. History -- Chapter 2. Research History of Corals and Coral Reefs in Cuba -- Part III. Description -- Chapter 3. Physical-Geographic Characteristics of Cuban Reefs -- Chapter 4. Outline of the Geology, Geomorphology and Evolution of the Late Qua-ternary Shelf and Uplifted Marine Terraces of Cuba; Tectonic and Sea Level Control of Present Day Coral Reef Distribution -- Chapter 5. A Remote Sensing Appraisal of the Extent and Geomorphological Diversity of the Coral Reefs of Cuba -- Part IV. Biota -- Chapter 6. Macrophytes Associated with Cuban Coral Reefs -- Chapter 7. Sponges: Conspicuous Inhabitants of the Cuban Coral Reefs and Their Potential as Bioindicators of Contamination -- Chapter 8. Species List of Cuban Stony Corals: Class Anthozoa, Order Scleractinia; Class Hydrozoa, Suborders Capitata and Filifera -- Chapter 9. Octocoral Forests: Distribution, Abundance, and Species Richness in Cuban Coral Reefs -- Chapter 10. Current State of Knowledge of Reef Mollusks in Cuba -- Chapter 11. Herbivory on Cuban Coral Reefs -- Chapter 12. Chronology of the Lionfish Invasion in Cuba and Evaluation of Impacts on Native Reef Fishes -- Chapter 13. Sharks and Rays in Cuban Coral Reefs: Ecology, Fisheries, and Conservation -- Chapter 14. Mesophotic Coral Ecosystems of Cuba -- Part V. Ecology, Conservation and Management -- Chapter 15. Status of Cuban Coral Reefs -- Chapter 16. Population Genetics of Cuba’s Scleractinian Corals -- Chapter 17. Multiple Cumulative Effects on Coral Reefs of the Northwestern Cuban Region -- Chapter 18. Guanahacabibes National Park: Research, Monitoring and Man-Agement for the Conservation of Coral Reefs -- Chapter 19. Ciénaga de Zapata Biosphere Reserve: Integrating Science with the Management of Coral Reefs -- Chapter 20. Coral Reefs in Cuban Marine Protected Areas -- Part VI. Economic Valuation -- Chapter 21. Economic Valuation of the Coral Reefs of Jardines de la Reina and Punta Francés National Parks, Cuba -- Chapter 22. The Economic Value of Coral Reefs in the Context of Marine Protected Areas: Experiences of the South Cuban Archipelago Project -- Chapter 23. Fish Can Be More Valuable Alive Than Dead.
    Abstract: This comprehensive volume gathers foremost experts on the coral reefs of Cuba who represent a spectrum of disciplines, including biology, conservation ecology, economics and geology. The volume is organized along general themes including the Cuban Reef biota, reefs occurring in the Mesophotic and Eutrophic zones, ecology, conservation, management and the economic importance of the coral reefs of Cuba. The combination of case studies, new and previously published research, historical overview and examples of the ways in which research has contributed to the management and conservation of Cuban coastal resources provides a unique reference for graduate students and professionals holding a wide range of interests and expertise related to coral reef systems.
    Type of Medium: Online Resource
    Pages: XI, 438 p. 176 illus., 147 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031367199
    Series Statement: Coral Reefs of the World, 18
    DDC: 577.6
    Language: English
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  • 90
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Ecology . ; Oceanography. ; Bioclimatology. ; Environmental management. ; Freshwater and Marine Ecology. ; Biodiversity. ; Biooceanography. ; Climate Change Ecology. ; Environmental Management. ; Ocean Sciences.
    Description / Table of Contents: Chapter 1. A Global View of the Cold-Water Coral Reefs of the World -- Chapter 2. Biology, Ecology and Threats to Cold-Water Corals on Brazil’s Deep-Sea Margin -- Chapter 3. Cold-Water Corals of the World: Gulf of Mexico -- Chapter 4. Cold-Water Coral Reefs of the Southeastern United States -- Chapter 5. Norwegian Coral Reefs -- Chapter 6. Waters of Ireland and the UK -- Chapter 7. Life and Death of Cold-Water Corals across the Mediterranean Sea -- Chapter 8. Cold-Water Coral Reefs in the Oxygen Minimum Zones off West Africa -- Chapter 9. New Zealand: South West Pacific Region -- Chapter 10. Deep-Sea Corals of the North and Central Pacific Seamounts.
    Abstract: Cold-water corals form reef structures in continental margin and seamount settings world-wide, making them more wide-spread and abundant than shallow-water reefs. Their role in these ecosystems is no less important than the influence that shallow-water coral reefs have on tropical systems. They create habitat structure, host endemic species, enhance elemental cycling, alter current flow, sequester carbon, and provide many other ecosystem services that we are just beginning to understand. The rapidly evolving state of knowledge of cold-water and deep-sea coral reefs has not been compiled in over 10 years. This volume synthesizes recent and historical information, reveals new findings from reefs that have been discovered only recently, and presents key avenues for future research. We are on the cusp of understanding the critical role that cold-water coral reefs play in the world’s oceans, and this book lays the foundation on which this knowledge will be built in the future.
    Type of Medium: Online Resource
    Pages: XVI, 293 p. 107 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031408977
    Series Statement: Coral Reefs of the World, 19
    DDC: 577.6
    Language: English
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  • 91
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Biotechnology. ; Plant genetics. ; Environmental policy. ; Biotechnology. ; Plant Genetics. ; Environmental Policy.
    Abstract: This book is a translation of an original French edition. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. The evolution of genome’s modification by genetic engineering was characterized by a major technological breakthrough with the discovery of CRISPR in 2012. A distinction is now made between first-generation biotechnologies developed in the 20th century and current second-generation biotechnologies, NGT or New Genomic Techniques, including genome editing. How do we consider these genomic modifications compared to those that occur spontaneously in nature? What are the applications of these techniques in the fields of plants, animals, and human health? What prospects in terms of development and independence for countries and at least what regulations are in force on the different continents? The book questions what GMOs are, genome editing products and the place of genomic transformations today and tomorrow in our societies. It tries to give some geostrategic and regulatory benchmarks on biotech products in order to better understand the current issues.
    Type of Medium: Online Resource
    Pages: XXI, 157 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031382376
    DDC: 660.6
    Language: English
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  • 92
    Keywords: Freshwater ecology. ; Marine ecology. ; Biodiversity. ; Zoology. ; Sustainability. ; Population biology. ; Conservation biology. ; Ecology . ; Freshwater and Marine Ecology. ; Biodiversity. ; Zoology. ; Sustainability. ; Population Dynamics. ; Conservation Biology.
    Description / Table of Contents: Part I. Fish Resources and Fishing Areas of the Western Balkans -- Chapter 1. Fish Resources of Inland Waters and Fisheries in Slovenia, Management, Sustainability and Conservation -- Chapter 2. Inland Fisheries in Croatia: Historical Aspects, Fish Resources, Management and Conservation -- Chapter 3. Fish Resources and Fisheries in Bosnia and Herzegovina – Overview, Sustainability, and Conservation -- Chapter 4. Inland Fisheries in Serbia: Historical Aspect, Fish Resources, Management and Conservation -- Chapter 5. The Freshwater Fish Resources and Freshwater Fisheries of Montenegro, Management, Sustainability and Conservation – With a Special Perspective on Lake Skadar -- Chapter 6. Fish and Fisheries of the Republic of North Macedonia, Current Situation and Its Perspective -- Chapter 7. Fish Resources of Inland Waters and Fisheries in Albania, Management, Sustainability and Conservation -- Part II. Some Fish Species of the Western Balkans Important for Fisheries and Conservation -- Chapter 8. Freshwater Crayfish of Western Balkan: Is It Possible to Use Them Sustainably or Do They Need Prompt Conservation Actions? -- Chapter 9. Salmonid Fish Species – Opportunities for Sustainable Use under Multiple Pressures and Current Climatic Change -- Chapter 10. Past and Future of Sturgeon Species (Acipenseridae) in Western Balkans – Case for Permanent Conservation or Sustainable Management -- Part III. Effects of Stressors on Inland Water Ecosystems and Fish Resources -- Chapter 11. Eutrophication of Fishing Waters and the Influence of Cyanobacterial Occurrence and Blooming on Fish Resources – Case Studies in Serbia -- Chapter 12. Pollution of Fishing Waters of the Western Balkan – Potentially Toxic Elements and Their Impact on the Ecological Sustainability of Fish Resources -- Chapter 13. Invasive Macroinvertebrate and Fish Species and Their Impact on Fish Resources: A Case Study on Fishing Waters of Serbia -- Part IV. Fish Stock Assessment Methods -- Chapter 14. A Brief Overview of the Development of the ES-HIPPO Model for Assessing the Sustainability and Conservation Priorities of Fish, Fish Resources, and Inland Water Habitats -- Part V. Conservation and Aquaculture -- Chapter 15. Тhe Role and Importance of Aquaculture for the Ecological Sustainability of Fish Resources in the Inland Water of Serbia -- Chapter 16. Huchen Hucho hucho (Linnaeus, 1758) in Croatia: Distribution, Genetic Diversity, Threats and Conservation -- Chapter 17. Future Perspective of Sustainable Development of Freshwater Fisheries and Conservation of Threatened Fish Species, Crustaceans and Molluscs -- Part VI. Social Aspect -- Chapter 18. Political and Socio-Economic aspects of Fisheries in Inland and Coastal Waters of the Western Balkan -- Chapter 19. Fish Resources of the Western Balkans, Sustainable Use and/or Conservation?.
    Abstract: This book provides a detailed evaluation of the hydro-ecological characteristics of the Western Balkans, an area characterized by still preserved inland waters and fish resources important for the European continent, as well as the biodiversity of inland waters important for the planet Earth. Freshwater ecosystems cover only 1% of the Earth's surface; however, they are a habitat for about 40% of fish species. At the same time, inland fisheries make less than 12% of the world's global fish catch, with 43% coming from low-income and food-deficient countries (Africa, South America, Southeast Asia). In Europe, the Western Balkans have significant fishing waters and fish resources, including the Middle Danube drainage (Sava, Drina, Velika Morava river systems), large ancient lakes (Skadar/Shkodra, Ohrid, Prespa, Dojran), and the Adriatic basin characterized by endemic and commercially important species. However, in contrast to the high fishing potential in a significant part of the Western Balkans, diverse and specific political, economic, and social factors largely had a negative impact on the state of fish resources. This volume is multidisciplinary and provides a sound knowledge base for scientific and practical fisheries. In addition, it may be a valuable guide for managers and conservationists worldwide to adapt methods and procedures for the ecological sustainability of fish resources under specific local, natural, and socio-economic conditions. Finally, the content is a good reference for natural sciences and agriculture students studying fish, fish resources, and fisheries sciences. It would improve their knowledge and perspectives on the challenges of sustainable use and conservation of inland water resources.
    Type of Medium: Online Resource
    Pages: XXII, 707 p. 261 illus., 233 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031369261
    Series Statement: Fish & Fisheries Series, 43
    DDC: 577.6
    Language: English
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  • 93
    Keywords: Biotechnology. ; Microbiology. ; Chemical engineering. ; Agricultural genome mapping. ; Biomaterials. ; Biotechnology. ; Microbiology. ; Chemical Process Engineering. ; Agricultural Genetics. ; Plant Materials.
    Description / Table of Contents: Methods for hemicellulose deconstruction aiming to xylose recovery: Recent progress and future perspectives -- Detoxification of hemicellulosic hydrolysates for improved xylitol production -- Fermentative production of xylitol from various lignocellulosic hydrolysates -- Strain improvement methods for enhanced xylitol production -- Fermentative methods for xylitol production: a comparative account on batch, fed-batch and continuous fermentation -- Methods for xylitol recovery: appraisal and future perspectives -- Critical analysis on xylitol production employing integrated approaches in sugarcane and corn processing mills -- Techno-economic analysis of xylitol production in standalone and integrated biorefineries -- Applications of xylitol in food, health and medical sector -- Market, consumption trends and commercial status of xylitol production.
    Abstract: This book explores recent advances in the microbial production of xylitol and its applications in food and medical sector. Xylitol is an important biomolecule from lignocellulose biorefinery which is produced from the xylose by chemical reactions or microbial fermentation methods. Currently, the demand of xylitol at commercial scale is being met through chemical methods. However, recent breakthroughs made in plant cell wall destruction, genetic engineering to develop the designer microorganisms, fermentation methods and media formulations and downstream processing have led the ways for sustainable production of xylitol at commercial scale in lignocellulose biorefineries. Microbial production of xylitol is preferred over the chemical processes as it is environmentally friendly, higher process efficiency with the desired product yield, and product recovery with minimum impurities. This book is a unique compilation of 11 book chapters written by experts in their respective fields. These chapters present critical insights and discuss the current progress and future progress in this area into fermentative xylitol production. Chapter 9 is licensed under the terms of the Creative Commons Attribution 4.0 International License. For further details see license information in the chapter.
    Type of Medium: Online Resource
    Pages: XII, 251 p. 40 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031049422
    DDC: 660.6
    Language: English
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  • 94
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Animal migration. ; Biology Technique. ; Physiology. ; Behavioral Neuroscience. ; Animal Migration. ; Experimental Organisms. ; Animal Physiology.
    Description / Table of Contents: Preface -- Chapter 1. Studying Birds -- Chapter 2. Mapping Sentences and Facet Theory -- Chapter 3. How to Develop a Mapping Sentence: The Example of Avian Sleep -- Chapter 4. Complex Avian Behaviour and Cognition: A Mapping Sentence Approach -- Chapter 5 -- Studying Avian Cognition in the Wild: Avian Psychometrics -- Chapter 6. Interpreting Avian Play, Murmuration of Starlings and Oology (Classifying Birds' Eggs) -- Chapter 7. Conclusion -- Glossary -- Index.
    Abstract: This book presents the facet theoretical framework as a tool for facilitating the conception of complex animal behaviour research and the design of research procedures through employing mapping sentences. Using the facet theoretical framework, this book takes a holistic view of bird behaviour. Components of bird behavior are identified and then reassembled to facilitate an understanding of the behaviour in the context of its natural occurrence. This provides new insight on both the parts of the behaviour and how these interact as a whole. The multi-faceted approach to designing, evaluating and understanding bird behavior presented offers a template that is adaptable for investigating a wide variety of avian species and different forms of behaviour. Behavioural biologists, animal and comparative psychologists, other natural and behavioural scientists, as well as students of these disciplines will find this book to be an interesting and enlightening read.
    Type of Medium: Online Resource
    Pages: XXXVII, 203 p. 29 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030121921
    DDC: 612.8
    Language: English
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  • 95
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Nanotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Genetics. ; Biotechnology. ; Nanotechnology. ; Microsystems and MEMS. ; Genetics and Genomics. ; Chemical Bioengineering.
    Description / Table of Contents: Introduction: DNA basics (a primer on DNA) -- Hiding and storing messages and data in DNA -- DNA as a nanoscale building material -- DNA machines and nanobots -- DNA-based nanoelectronics -- Concluding remarks.
    Abstract: This is the first book portraying to a wide readership many fields of DNA in the world of materials altogether in a single volume. The book provides underlying concepts and state-of-art developments in the emerging fields of DNA electronics, structural DNA nanotechnology, DNA computing and DNA data storage, DNA machines and nanorobots. Future possibilities of innovative DNA-based technologies, such as DNA cryptography, DNA identity tags, DNA nanostructures in biosensing and nanomedicine, as well as DNA-based nanoelectronics are all covered, too. This book is valuable for university students studying engineering and technology; biotech, nanotech, and medical device R&D managers, practitioners and investors; and IP analysts who would like to extend their background in advanced DNA technologies. It is nicely illustrated, which makes it very readable, and it conveys science and principles in a lively language to appeal to a broad audience, from professionals and academics to students and lay readers. Advance Praise for DNA Beyond Genes: “Most students of DNA, and lay readers as well, are interested in the absolutely essential role it plays in biology. However, the properties which make DNA the carrier of genetic information also make it an extraordinary material that can be used as the backbone for a wide variety of nanoengineering applications – these range from information storage and computation to molecular machines and devices to artfully designed logos and symbols. The perfect self-recognition of DNA sequences makes it an ideal building block to synthesize more and more elaborate constructions and imaginative scientists have probably only just scratched the surface of what can eventually be created. Here for the first time in this wonderful book Vadim Demidov explores the full range of the non-biological applications of DNA.” Charles R. Cantor Professor Emeritus of Biomedical Engineering, Boston University Member of the USA National Academy of Sciences.
    Type of Medium: Online Resource
    Pages: XX, 107 p. 66 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030364342
    DDC: 660.6
    Language: English
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  • 96
    Keywords: Neurosciences. ; Public health. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Public Health. ; Biomedical Research.
    Description / Table of Contents: 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection.
    Abstract: This book examines the correlation of the coronavirus disease-19 [CE1] [AAS2] (COVID-19) infection with sleep, circadian rhythm, and sleep disorders. The chapters of the book explore sleep problems during the COVID-19 pandemic and its association with psychological distress and also review the prevalence of clinical cases of insomnia, anxiety, and depression in COVID-19 patients. The book further presents the correlation between sleep, circadian rhythms, and immunity that contributes toward more severe COVID-19. It summarizes the evidence on the interplay between circadian biology, sleep, and COVID-19. The chapters of the book discuss the relationship between obstructive sleep apnea (OSA) and adverse COVID-19 outcomes. Towards the end, the book presents studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin and provides mechanistic insights into the potential therapeutic use of melatonin during the SARS-CoV-2 infection. The last chapter describes the publication output of sleep-related research during the pandemic and provides an overview and trends on sleep and covid-19 publication output. This book is an excellent source for neurologists, sleep specialists, and public health specialists.
    Type of Medium: Online Resource
    Pages: XXVI, 430 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819902408
    Series Statement: Progress in Sleep Research,
    DDC: 612.8
    Language: English
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  • 97
    Keywords: Biotechnology. ; Nanotechnology. ; Regenerative medicine. ; Immunology. ; Biotechnology. ; Nanotechnology. ; Regenerative Medicine and Tissue Engineering. ; Immunology.
    Description / Table of Contents: Chapter 1. Nanomaterials, classifications, and properties -- Chapter 2. Engineering nanomaterials for bio-interfacing -- Chapter 3. Biomaterials and surface modification strategies -- Chapter 4. Nano materials as a nanotheronostic agent -- Chapter 5. Nanobiomaterials in biomedicine: Designing strategies and critical concepts -- Chapter 6. Phytofabricated nanodelivery systems: Engineering principles and applications -- Chapter 7. Nanobiosensors based diagnostics system: Transducers and surface materials -- Chapter 8. Nanobiomaterials and nanocomposites in clinical diagnostics -- Chapter 9. Tissue Engineering and Regenerative Medicines based on nanobiomaterials -- Chapter 10. Prospects and advantages of microfluidics utilizing various nanobiomaterials -- Chapter 11. Electrochemical nanoengineered sensors in infectious disease diagnosis -- Chapter 12. Multiplexing utilizing various nanobiomaterials -- Chapter 13. Future perspects of nanobiomaterials in human health care -- Chapter 14. Commercial aspects of nanobiomaterials: Short-coming and future aspects.
    Abstract: This book comprehensively documents the application of Nanobiomaterials in the field of bio-medicine and diagnostics technologies by involving classical concepts/examples. Nanobiotechnology is an emerging area which encompasses all the facets of research of nano and biomaterials with their interaction with biological systems. The book summarises design and development of various nanobiomaterials and their composites for diagnostics and therapeutic applications. It skilfully reviews the utilization of the nanomaterials alone or in combination with other bio-molecules as a contrast enhancer in in-vivo imaging, Nano-Theranostics, drug delivery, and sensing transducer matrix. It also discusses the current research on designing of the new Nanobiomaterials and their implementation in numerous fields including bio-medicine and diagnostics. Finally, it summarizes the future prospects and the commercial viability of Nanobiomaterials in the human health care.
    Type of Medium: Online Resource
    Pages: XII, 294 p. 108 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813298408
    DDC: 660.6
    Language: English
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  • 98
    Keywords: Biotechnology. ; Biomaterials. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Insights into the emergence, clinical prevalence and significance of Staphylococcus aureus small colony variants -- Periprosthetic Joint Infection -- Complications in orthopedic trauma surgery: fracture related infection -- Chiral Stereochemical Strategy for Antimicrobial Adhesion -- Perspectives on and need to develop new infection control strategies -- Battling bacteria with free and surface-immobilized polymeric nanostructures -- Engineering Approaches to Create Antibacterial Surfaces on Biomedical Implants and Devices -- 3D Printed Ceramic-Polymer Composites for Treating Bone Infection -- Bioinspired interfaces for the management of skin infections -- Antimicrobial endodontic materials -- Local Delivery of Anti-biofilm Therapeutics -- Device-Related Infections -- Advances in polysaccharide based antimicrobial delivery vehicles -- Antibacterial Coatings on Medical Implants -- Perspectives on biomaterial-associated infection: pathogenesis and current clinical demands -- Polymeric Nanoparticulate Delivery Vehicles of Antimicrobials for Biofilm Eradication -- Pathogenesis of biomaterial-associated infection -- Metal- and Polymer-Based Nanoparticles for Advanced Therapeutic and Diagnostic System Applications -- Antimicrobial Material in Arthroplasty -- Antimicrobial Hydrogels: Key Considerations and Engineering Strategies for Biomedical Applications -- Antibacterial Polymeric and Peptide Gels/Hydrogels to Prevent Biomaterial-related Infections -- The Impact of Bacterial Biofilms in Transfusion Medicine -- Mechanisms of Action and Chemical Origins of Biologically Active Antimicrobial Polymers -- When the Race is Lost: The Clinical Impact of Prosthetic Joint Infections -- Antibacterial Hydroxyapatite: An Effective Approach to Cure Infections in Orthopedics -- Index.
    Abstract: This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.
    Type of Medium: Online Resource
    Pages: XI, 650 p. 158 illus., 122 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030344757
    DDC: 660.6
    Language: English
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  • 99
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Biotechnology. ; Chemical Bioengineering.
    Description / Table of Contents: Chapter 1. Introduction of nanobiotechnology (Kwee Yum Lee, Xuan-Hung Pham, Won-Yeop Rho, Hyejin Chang, Sang Hun Lee, Jaehi Kim, Eunil Hahm, Jong Hun Lee, Yoon-Sik Lee, Bong-Hyun Jun) -- Chapter 2. General in Colloidal Nanoparticles (Jaehi Kim, Xuan-Hung Pham, Hyejin Chang, Byung Sung Son, Eunil Hahm, Sang Hun Lee, Won-Yeop Rho, Bong-Hyun Jun) -- Chapter 3. Silica Nanoparticles (HyeJin Chang, Jaehi Kim, Won-Yeop Rho, Xuan-Hung Pham, Jong Hun Lee, Sang Hun Lee, Dae Hong Jeong, Bong-Hyun Jun) -- Chapter 4. Luminescent Nanomaterials (I) (Hyejin Chang, Michael M. Murata, Won-Yeop Rho, Jaehi Kim, Jong Hun Lee, Sang Hun Lee, Dae Hong Jeong, Bong-Hyun Jun) -- Chapter 5. Luminescent nanomaterials (II) (Hyejin Chang, Jaehi Kim, Sang Hun Lee, Won-Yeop Rho, Jong Hun Lee, Dae Hong Jeong, Bong-Hyun Jun) -- Chapter 6. Plasmonic Nanoparticles: Basics to Applications (I) (Hyejin Chang, Won-Yeop Rho, Byung Sung Son, Jaehi Kim, Sang Hun Lee, Dae Hong Jeong, Bong-Hyun Jun) -- Chapter 7. Plasmonic Nanoparticles: Advanced Researches (II) (Hyejin Chang, Sang Hun Lee, Jaehi Kim, Won-Yeop Rho, Xuan-Hung Pham, Dae Hong Jeong, Bong-Hyun Jun) -- Chapter 8. Magnetic Nanoparticles (San Kyeong, Jaehi Kim, Hyejin Chang, Sang Hun Lee, Byung Sung Son, Jong Hun Lee, Won-Yeop Rho, Xuan-Hung Pham, Bong-Hyun Jun) -- Chapter 9. Lithography Technology for Micro- and Nanofabrication (Da-hee Baek, Sang Hun Lee, Bong-Hyun Jun, and Seung Hwan Lee) -- Chapter 10. Bioapplications of Nanomaterials (Kim-Hung Huynh, Kwee Yum Lee, Hyejin Chang, Sang Hun Lee, Jaehi Kim, Xuan-Hung Pham, Yoon-Sik Lee, Won-Yeop Rho, Bong-Hyun Jun) -- Chapter 11. Carbon nanomaterials for biomedical application (Sang Hun Lee, Won-Yeop Rho, Hyejin Chang, Jong Hun Lee, Jaehi Kim, Seung Hwan Lee, and Bong-Hyun Jun) -- Chapter 12. Optical and Electron Microscopy for Analysis of Nanomaterials (Hyoyeon Kim, Michael M. Murata, Hyejin Chang, Sang Hun Lee, Jaehi Kim, Jong Hun Lee, Won-Yeop Rho, Bong-Hyun Jun) -- Chapter 13. Conclusion and Perspective (Jaehi Kim, Xuan-Hung Pham, Hyejin Chang, Sang Hun Lee, Won Yeop Rho, Byung Sung Son, Yoon-Sik Lee, Dae Hong Jeong, Bong-Hyun Jun).
    Abstract: This book documents the tremendous progress in the use of nanotechnology for a range of bioapplications with the aim of providing students, researchers, technicians, and other professionals with an up-to-date overview of the field. After a general introduction to the surface modifications of nanoparticles required for different biological applications, and to the properties of the modified nanoparticles, a series of chapters describe the state of the art in respect of different types of nanoparticle, including silica nanoparticles, fluorescent nanomaterials, metal nanoparticles, magnetic nanoparticles, carbon-based nanostructures, and other novel nanomaterials. Detailed information is supplied on methods of preparation, chemical and physical properties, and current and potential applications. The closing chapters discuss lithography methods for the top-down approach to nanoparticle synthesis and the use of spectroscopic studies as a tool for the characterization of each nanoparticle. Future prospects and challenges for the development of further nanomaterials with bioapplications are also covered.
    Type of Medium: Online Resource
    Pages: VI, 292 p. 119 illus., 97 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813361584
    Series Statement: Advances in Experimental Medicine and Biology, 1309
    DDC: 660.6
    Language: English
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  • 100
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Biology Technique. ; Biotechnology. ; Biomedical Research. ; Experimental Organisms.
    Description / Table of Contents: Morphology Study – Optical Microscopy Imaging, Electron Microscopy Imaging, Confocal Microscopy Imaging, Live Cell Imaging -- Methods to Detect Autophagic Flux -- Biomarkers in Autophagy -- Drugs and Molecular Biology Technology in Autophagy Study -- Animal Models in Autophagy Study.
    Abstract: This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 3 focuses on the technical aspects of autophagy research. It is comprised of two parts. The first part discusses the basic process of autophagy, including its overall classification and individual stages in the life cycle of autophagosomes. The second part discusses the tools, strategies, and model systems in current autophagy research, including cell and animal models, detection and manipulation methods, as well as screening, genomic, proteomic and bioinformatic approaches. The book is written and edited by a team of active scientists. It is intended as a practical reference resource for interested researchers to get started on autophagy studies.
    Type of Medium: Online Resource
    Pages: XIV, 453 p. 85 illus., 79 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811628306
    Series Statement: Advances in Experimental Medicine and Biology, 1208
    DDC: 660.6
    Language: English
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