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Cup–plate Assay of Serum Fibrinolysin

Abstract

IN recent years, attention has been given to the quantitative estimation of serum fibrinolysin. Study of the plate test of Permin1 indicated that some modification of this method was necessary to estimate numerous unknown enzyme samples. The cup–plate assay method described by Dingle, Reid and Solomons2 seemed suitable, since it was designed to estimate large numbers of samples over a wide range of enzyme concentrations. We have found that a combination of the principles of these two methods is applicable to the measurement of serum fibrinolysis.

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References

  1. Permin, P. M., Nature, 160, 571 (1947). “Fibrinolytiske Enzymer”, thesis, Copenhagen (1949); Acta Physiol. Scand., 20, 388 (1950).

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  2. Reid, W. W., Nature, 166, 569 (1950). Dingle, J. T., Reid, W. W., and Solomons, G. L., J. Sci. Food and Agric., 3, 149 (1953).

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  3. Brownlee, K. A., et al., J. Gen. Microbiol., 2, 40 (1948).

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DINGLE, J., THOMAS, D. Cup–plate Assay of Serum Fibrinolysin. Nature 175, 728–729 (1955). https://doi.org/10.1038/175728b0

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  • DOI: https://doi.org/10.1038/175728b0

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