Abstract
We performed fed-batch and continuous fermentations to extend the time of maximal nikkomycin production by Streptomyces tendae Tü 901/S 2566. This was achieved by the fed-batch culture technique. Furthermore, high productivity was obtained at slow growth rates in a continuous fermentation process. Different dilution rates with and without carbon limitation were done and the results were compared.
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Schüz, T.C., Fiedler, HP. & Zähner, H. Optimized nikkomycin production by fed-batch and continuous fermentation. Appl Microbiol Biotechnol 39, 433–437 (1993). https://doi.org/10.1007/BF00205028
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DOI: https://doi.org/10.1007/BF00205028