Abstract
Feeding of raw and heated soy flour (RSF & HSF) for 4 or 8 weeks to weanling swine was compared with feeding of casein diets. There was essentially no growth in pigs fed RSF, whereas body weight increased 4.5 fold over 8 weeks with either casein or HSF. No change in pancrease weight as percent body weight was found in any group in either experiment. Both total pancreatic RNA and DNA were decreased in RSF groups, although RNA and DNA/mg pancreas were increased by the RSF diets. Total pancreatic protein, as well as protein/mg, were decreased in RSF-fed pigs compared to casein and HSF. Pancreatic trypsin, chymotrypsin, lipase, and amylase, and fecal trypsin were decreased in RSF-fed pigs to varying degrees compared to either HSF or casein. HSF and casein performance was equivalent in all parameters measured. Results of these experiments are compared with results of feeding similar diets to rats and monkeys.
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References
FAO/WHO (1973) Energy and Protein Requirements. World Health Org Tech Rep Ser No 522
Gertler A, Birk Y, Bondi A (1967) A comparative study of the nutritional and physiological significance of pure soybean trypsin inhibitors and of ethanol-extrated soybean meals in chicks and rats. J Nutr 91:358–370
Harper AE (1979) Human requirements for lysine and sulfur amino acids. In: Wilcke HL, Hopkins DT, Waggle DH (eds.)Soy Protein and Human Nutrition. New York: Academic Press pp 171–186
Kakade ML, Hoffa DE, Leiner IE (1973) Contribution of trypsin inhibitors to the deleterious effect of unheated soybeans fed to rats. J Nutr 103:772–778
Kakade ML, Thompson RD, Engelst WE, Behrns GC, Yoder RD (1975) Failure of soybean trypsin inhibitor to exert deleterious effects in calves. J Dairy Sci 59:1484–1489
Liener IE (1978) Protease inhibitors and other toxic factors in seeds. In:Plant Proteins Norton GE (ed), London: (Butterworth and Co), pp 117–140
Liener IE (1977) Toxicological considerations in the utilization of new protein foods (Adler-Nissen J (ed) (Copenhagen, Denmark: FEBS), pp 129–138
McGuiness EE, Morgan RGH, Levinson DA, Frape DL, Hopwood D, Wormsley KG (1980) The effects of long term feeding of soya flour on the rat pancreas. Scand J Gastroenterol 15:497–502
McGuiness EE, Morgan RGH, Levinson DA, Hopwood D, Wormsley KG (1981) Interaction of azaserine and raw soya flour on the rat pancreas. Scand J Gastroenterol 16:49–56
Morgan RGH, Wormsley KG (1977) Cancer of the pancreas. Gut 18:580–596
National Research Council (1978) Nutrient requirements of the laboratory rat. In: Nutrient Requirements of Laboratory Animals, 3rd rev. ed., National Academy of Sciences, Washington DC, pp 7–37
Nitsan Z, Liener IE (1976) Enzymic activities in the pancreas, digestive tract and feces of rats fed raw or heated soy flour. J Nutr 106:300–305
Steele RGD, Torrie JH (1960)Principles and Procedures of Statistics McGraw-Hill Book Co. New York: pp 16–18, 106–198
Struthers BJ, MacDonald JR, Dahlgren RR, Hopkins DT (1983) Effects on the monkey, pig, and rat pancreas of soy products with varying levels of trypsin inhibitor and comparison with the administration of cholecystokinin. J Nutr 113:86–97
Yen JT, Hymowitz T, Jensen AH (1974) Effects of soybeans of different trypsin inhibitor activities on performance of growing swine. J Anim Sci 38:304–309
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Struthers, B.J., Macdonald, J.R. Effects of raw soy flour feeding in weanling pigs: comparison with rats and monkeys. Plant Food Hum Nutr 35, 331–337 (1985). https://doi.org/10.1007/BF01092202
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DOI: https://doi.org/10.1007/BF01092202