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Effect of dimethylsulfate on the structure and cytoarchitectonics of rat thymus

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Changes of structure and cell ratios of different functional zones in the thymus under conditions of long-term dimethylsulfate administration at 0.1 and 2.0 mg/m3 on the organism are studied morphometrically on histological preparations from Wistar rats. Cyclic reactions of the thymus to the toxic substance are found to be due to compensatory processes. It is shown that the nature of the reaction does not depend on the concentration of toxic substance but that the extent of changes is a function of the dimethylsulfate concentration.

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Authors and Affiliations

  1. Laboratory of Functional Anatomy, Research Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow

    L. M. Erofeeva & M. R. Sapin

Authors
  1. L. M. Erofeeva
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  2. M. R. Sapin
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 1, pp. 96–100, January, 1995

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Erofeeva, L.M., Sapin, M.R. Effect of dimethylsulfate on the structure and cytoarchitectonics of rat thymus. Bull Exp Biol Med 119, 91–95 (1995). https://doi.org/10.1007/BF02445942

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  • DOI: https://doi.org/10.1007/BF02445942

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