Summary
This paper describes the induction of uterine eosinophilia as well as of deep endometrial edema and increase of uterine wet weight in the immature rat by the catecholestrogens 2-OH-estradiol and 4-OH-estradiol. These effects are thought to be mediated by eosinophils via a specific eosinophil receptor system. 4-OH-estradiol was equipotent with estradiol, whereas the effect of 2-OH-estradiol was significantly weaker.
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01 March 1986
An Erratum to this paper has been published: https://doi.org/10.1007/BF01942525
Literature
Jensen, E. V., and De Sombre, E. R., A. Rev. Biochem.41 (1972) 203.
Tchernitchin, A., Steroids19 (1972) 575.
Tchernitchin, A. N., J. Steroid Biochem.19 (1983) 95.
Tchernitchin, A., J. Steroid Biochem.4 (1973) 277.
McLusky, N. J., Barnes, E. R., Clark, C. R., and Naftolin, F., in: Catecholestrogens, p. 151–165. Eds. R. G. Merriam and M. B. Lipsett, Raven Press, New York 1983.
Stubenrach, G., and Knuppen, R., Steroids28 (1976) 733.
Schneider, W. C., in Methods in Enzymology III, pp. 680–684. Eds. S. P. Colwick and N. O. Kaplan. Academic Press, New York 1957.
Bradford, M., Analyt. Biochem.72 (1974) 248.
Tchernitchin, A., Roorjick, R., Tchernitchin, X., Vandenhende, J., and Galand, P., Nature248 (1974) 142.
Grunert, G., and Tchernitchin, A. N., J. Endocr.94 (1982) 307.
Grunert, G., Fernandez, S., and Tchernitchin, A. N., Hormone Res.19 (1984) 253.
Ball, P., and Knuppen, R., Acta Endocr.93 Suppl. 232 (1980) 98.
Lipsett, M. B., Merriam, G. R., Kono, S., Brandon, D. D., Pfeiffer, D. G., and Loriaux, D. L., in: Catecholestrogens, pp. 105–114. Eds. G. R. Merrian and M. B. Lipsett. Raven Press, New York 1983.
Clark, J. H., and Peck, E. J. Jr., Female Sex Steroids-Receptors and Functions. Springer Verlag, Berlin 1979.
Katzenellenbogen, B. S., and Gorski, J., in: Biochemical Action of Hormones, p. 187–243. Eds. G. Litwack, Academic Press, New York 1975.
Gorski, J., and Gannon, F., A. Rev. Physiol.38 (1976) 425.
Tchernitchin, A. N., and Galand, P., J. Endocr.99 (1980) 123
Tchernitchin, A. N., Barrera, J., Arroyo, P., Mena, M. A., Vilches, K., and Grunert, G., Agents Actions, in press 1985.
Grunert, G., Porcia, M., Neumann, G., Sepulveda, S., and Tchernitchin, A. N., J. Endocr.102 (1984) 295.
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Acknowledgments. This work was supported by Grant B-1493-8435 from the University of Chile. We are indebted to Prof. R. Knuppen, Lübeck, for providing the CE.
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Baumann, P., Tchernitchin, A.N., Grunert, G. et al. Effect of various doses of catecholestrogens on uterine eosinophilia in the immature rat. Experientia 42, 165–167 (1986). https://doi.org/10.1007/BF01952449
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DOI: https://doi.org/10.1007/BF01952449