Summary
Hydrochlorothiazide, acutely injected in rats, has a weak analgesic activity per se and potentiates and prolongs the antinociceptive effect of morphine.
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This work was supported in part by grants from Consiglio Nazionale delle Ricerche, and by Ministero della Pubblica Istruzione, Roma.
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Poggioli, R., Vergoni, A.V. & Bertolini, A. Influence of hydrochlorothiazide on the pain threshold and on the antinociceptive activity of morphine, in rats. Experientia 41, 265–266 (1985). https://doi.org/10.1007/BF02002628
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DOI: https://doi.org/10.1007/BF02002628