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Regioselectivity in the oxidative deamination of 2-methyl-1,4-diaminobutane catalyzed by diamine oxidases

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  • Chimica, Biochimica
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Summary

Diamine oxidase from pea seedlings (PDAO) catalyzes the oxidation of 2-methyl-1,4-diaminobutane in a regioselective fashion, whereas diamine oxidase from pig kidney (KDAO) shows no regioselectivity for the same reaction.

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Authors and Affiliations

  1. Istituto di Chimica, Facoltà di Medicina, Università di Milano, Via Saldini, 50, I-20133, Milano, Italy

    E. Santaniello, Ada Manzocchi, P. A. Biondi & Tatjana Simonic

  2. Istituto di Fisiologia Veterinaria e Biochimica, Università di Milano, Via Celoria, 10, I-20133, Milano, Italy

    E. Santaniello, Ada Manzocchi, P. A. Biondi & Tatjana Simonic

Authors
  1. E. Santaniello
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  2. Ada Manzocchi
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  3. P. A. Biondi
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  4. Tatjana Simonic
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Additional information

This work was supported by ‘Ministero della Pubblica Istruzione’. We thank Prof. A. Fiecchi and Prof. S. Ronchi for many helpful discussions.

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Santaniello, E., Manzocchi, A., Biondi, P.A. et al. Regioselectivity in the oxidative deamination of 2-methyl-1,4-diaminobutane catalyzed by diamine oxidases. Experientia 38, 782–784 (1982). https://doi.org/10.1007/BF01972268

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  • DOI: https://doi.org/10.1007/BF01972268

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