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Methods for the synthesis of thyroxine and triiodothyronine

  • Methods of Synthesis and Technology of Drug Production
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Literature cited

  1. A. s. 405869, USSR (1971).

  2. T. Berzin, The Biochemistry of Hormones [in Russian], Moscow (1964).

  3. B. M. Gorovits, E. A. Eremin, and A. P. Osipov, Zh. Vses. Khim. Obshch. im. G. I. Mendeleeva,34 No. 1, 125 (1989).

    Google Scholar 

  4. S. A. Eremin and S. K. Morales, All-Union Conference on the Use of Enzymes in Biochemical Analyses: Abstracts. Palanga (1982), Part 2, p. 19.

  5. P. Karrer, Course in Organic Chemistry [Russian translation], Leningrad (1960).

  6. V. R. Klyachko, Sov. Med., No. 9, 44–52 (1975).

    Google Scholar 

  7. M. D. Mashkovskii, Therapeutic Substances [in Russian], Moscow (1984), Vol. 1, pp. 544–548.

    Google Scholar 

  8. D. B. Papkovskii, O. A. Stafeeva, and A. P. Savitskii, Probl. Endokrinol.,34, No. 1, 57–61 (1988).

    Google Scholar 

  9. Patent 598691, England (1948); Chem. Abstr.,43, 262 (1949).

  10. Patent 65933, GDR (1970).

  11. Patent 2435947, USA (1948); Chem. Abstr.,42, 2732 (1948).

  12. Patent 2784222, USA (1957).

  13. Patent 2823164, USA (1958).

  14. Patent 2839583, USA (1958).

  15. Patent 2886592, USA (1959).

  16. Patent 2894977, USA (1959).

  17. Patent 2895927, USA (1959).

  18. Patent 2993928, USA (1961).

  19. Patent 896946, FRG (1953).

  20. Patent 1064529, FRG (1960).

  21. Patent 1065855, FRG (1960).

  22. Patent 1077673, FRG (1961); Chem. Abstr.,55, N14390e (1961).

  23. Z. N. Rosen, Basic Endocrinology [Russian translation], Moscow (1980).

  24. M. V. Rubtsov and A. G. Baichikov, Synthetic Chemicopharmaceutical Drugs [in Russian], Moscow (1971), pp. 111–114.

  25. Contemporary Hormonal Drugs of Animal Origin: Review [in Russian], P. M. Kochergin (ed.), Moscow (1983), pp. 14–16.

  26. Contemporary Hormonal Drugs of Animal Origin: Review [in Russian], P. M. Kochergin and G. T. Chernenko, eds., Moscow (1984), pp. 2–36.

  27. Ya. Kh. Turakulov, The Normal and Pathological Biochemistry of Tyroid Hormones [in Russian], Tashkent (1962).

  28. Ya. Kh. Turakulov, T. A. Babaev, and T. Saatov, Thyroid Iodoproteins [in Russian], Tashkent (1974).

  29. I. V. Tysyachnaya, V. I. Yakovleva, and A. K. Aren, Prikl. Biokhim.,17, No. 5, 645–649 (1981).

    Google Scholar 

  30. I. V. Tysyachnaya, M. Kh. Rodriges, V. I. Yakovleva, et al., Prikl. Biokhim.,20, No. 1, 79–87 (1984).

    Google Scholar 

  31. V. I. Yakovleva, M. B. Kuplyatskaya, and I. V. Tysyachnaya, Vestn. MGU, Ser., 2,20, No. 5, 485–498 (1979).

    Google Scholar 

  32. G. H. Barnes, J. Chem. Soc., pp. 2824–2833 (1950).

  33. F. M. Beringer et al., J. Am. Chem. Soc.,75, 2705–2708 (1953).

    Google Scholar 

  34. B. Blank, R. F. Pfeiffer, M. C. Greenberg, et al., J. Med. Chem.,6, 554–563 (1963).

    Google Scholar 

  35. P. Block and G. Powell, J. Am. Chem. Soc.,65, 1430–1431 (1943).

    Google Scholar 

  36. M. B. Bolger, B. Michael, E. C. Jorgensen, et al., J. Biol. Chem.,255, 10271–10278 (1980).

    Google Scholar 

  37. E. T. Borrows, Y. C. Clayton, and B. A. Hems, J. Chem. Soc., Supplement 1, p. 185 (1949).

    Google Scholar 

  38. E. T. Borrows, Y. C. Clayton, B. A. Hems, and A. G. Long, J. Chem. Soc., Supplement 1, pp. 190–199 (1949).

    Google Scholar 

  39. M. Bovarnick, K. Bloch, and G. L. Foster, J. Am. Chem. Soc.,61, 2472–2474 (1939).

    Google Scholar 

  40. A. Burger, Medicinal Chemistry (3rd edn.), New York (1970), part 2, pp. 838–858.

  41. A. Canzenelli, C. R. Harington, and C. C. Randall, Biochem. J.,28, 68 (1934).

    Google Scholar 

  42. Y. R. Chalmers, G. T. Dickson, Y. Elks, and B. A. Hems, J. Chem. Soc., 3424–3433 (1949).

  43. S. W. Dietrich, M. B. Bolger, P. A. Kollman, and E. C. Jorgensen, J. Med. Chem.,20, 863–880 (1977).

    Google Scholar 

  44. H. Erikson, J. Nilsson, and B. Mattiasson, Appl. Biochem. Biotechnol.,8, 1–8 (1983).

    Google Scholar 

  45. Y. Gross and R. Pitt-Rivers, Lancet,ii, 766 (1951).

    Google Scholar 

  46. Y. Gross and R. Pitt-Rivers, Biochem. J.,53, 645–654 (1953).

    Google Scholar 

  47. C. R. Harington, Biochem. J.,20, 293–300 (1926).

    Google Scholar 

  48. C. R. Harington and R. Barger, Biochem. J.,21, 169 (1927).

    Google Scholar 

  49. C. R. Harington, Biochem. J.,22, 1429 (1928).

    Google Scholar 

  50. C. R. Harington, The Thyroid Gland: Its Chemistry and Physiology, Oxford (1933).

  51. B. A. Hems, Chem. Ind., p. 663 (1950).

  52. G. Hillmann, Z. Naturforsch.,115, 419–420 (1956).

    Google Scholar 

  53. G. Hillmann, Z. Naturforsch.,118, 424.

  54. D. Ira, Y. George, G. Cyrena, et al., J. Biol. Chem.,251, 4233–4238 (1976).

    Google Scholar 

  55. E. C. Jorgensen and R. A. Wiley, J. Med. Pharm. Chem.,5, 1307 (1962).

    Google Scholar 

  56. E. C. Jorgensen, J. Med. Chem.,7, 701–705 (1964).

    Google Scholar 

  57. E. C. Jorgensen and J. A. W. Reid, J. Med. Chem.,8, 533–536 (L965).

  58. E. C. Jorgensen et al., Excerpta Med. Int. Congr. Ser., p. 403 (1977).

  59. E. C. Kendall, Throxine, New York (1929).

  60. O. Kennard, Biochem. J.,53, 650–652 (1953).

    Google Scholar 

  61. G. Kleinhammer, H. Zenz, R. Zinke, et al., Enzyme Immunoassay, Stuttgart (1978), pp. 42–51.

  62. R. Y. Meltzer and R. Y. Stanabak, J. Org. Chem.,26, 1977 (1961).

    Google Scholar 

  63. The Merck Index: An Encyclopedia of Chemicals and Drugs [9th edition), (1976), pp. 1116, 1215, 1243–1244.

  64. H. Nahm and W. Siedel, Chem. Ber.,96, 1–9 (1963).

    Google Scholar 

  65. A. Nishinaga, H. Kon, and H. J. Cahnmann, J. Org. Chem.,33, 157–162 (1968).

    Google Scholar 

  66. R. Pitt-Rivers, Biochim. Biophys. Acta,2, 311–318 (1948).

    Google Scholar 

  67. R. Pitt-Rivers, Nature,161, 308 (1948); Chem. Abstr.,42, N4142a (1948).

    Google Scholar 

  68. R. Pitt-Rivers, Biochem. J.,43, 223–231 (1948); Chem. Abstr.,43, N2256b (1949).

    Google Scholar 

  69. R. Pott-Rivers and J. R. Tata, The Thyroid Hormones, London (1959).

  70. R. Pitt-Rivers and J. R. Tata, Chem. Abstr.,54, N25242h (1960).

    Google Scholar 

  71. J. Roche and R. Michel, Adv. Protein Chem.,6, 253 (1951).

    Google Scholar 

  72. J. Roche, R. Lissitzky, and R. Michel, C. R. Acad. Sci. (Paris),234, 997 (1952).

    Google Scholar 

  73. J. Roche, C. R. Acad. Sci. (Paris),239, 597 (1954).

    Google Scholar 

  74. J. Roche, R. Michel, and W. Wolf, C. R. Acad. Sci. (Paris),240, 251–253 (1955).

    Google Scholar 

  75. J. Roche, R. Michel, W. Wolf, et al., C. R. Acad. Sci. (Paris), 921–923 (1955).

  76. J. Roche, C. R. Acad. Sci. (Paris),243, 1067 (1956).

    Google Scholar 

  77. J. Roche, R. Michell, and W. Wolf, Bull. Soc. Chim. Fr.,4, 462–471 (1957).

    Google Scholar 

  78. S. R. Singh, A. C. Carter, D. M. Kydd, et al., Endocrinol. Res. Commun.,3, 119–131 (1976).

    Google Scholar 

  79. F. Vilalonga, Pub. Centr. Invest. Tisiol.,14, 63–71 (1952); Chem. Abstr.,46, N2524a (1952).

    Google Scholar 

  80. W. M. Wiersinga and Y. J. Chopra, Meth. Enzymol.,84D, 272–303 (1982).

    Google Scholar 

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Authors and Affiliations

  1. S. Ordzhonikidze Science Research Chemicopharmaceutical Institute, Moscow

    P. M. Kochergin, R. M. Palei, A. N. Kravchenko & E. V. Popova

Authors
  1. P. M. Kochergin
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  2. R. M. Palei
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  3. A. N. Kravchenko
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  4. E. V. Popova
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Translated fron Khimiko-farmatsevticheskii Zhurnal, Vol. 24, No. 6, pp. 43–49, June, 1990.

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Kochergin, P.M., Palei, R.M., Kravchenko, A.N. et al. Methods for the synthesis of thyroxine and triiodothyronine. Pharm Chem J 24, 430–438 (1990). https://doi.org/10.1007/BF00765794

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  • DOI: https://doi.org/10.1007/BF00765794

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