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The relative effect of 2,3-diphosphoglycerate on the oxygen affinity of fetal and adult hemoglobin in whole blood

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Riassunto

Experimenti condotti sul sangue intero di individui neonati e adulti hanno dimostrato che l'affinità del sangue per l'ossigeno (P 50) dipende dalla concentrazione intraeritrocitaria di 2,3-difosfoglicerato (DPG) e dalle proporzioni relative di emoglobina adulta (HbA) e fetale (HbF). I risultati ottenuti indicano che nel sangue in toto l'effetto del DPG sulla P50 della HbF è circa il 40% di quello sulla P50 della HbA.

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Author notes

  1. M. M. Orzalesi

    Present address: M. M. O., Via Cimone 93, B, 00141, Roma, Italy

Authors and Affiliations

  1. Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA

    M. M. Orzalesi & W. W. Hay

Authors
  1. M. M. Orzalesi
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  2. W. W. Hay
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Orzalesi, M.M., Hay, W.W. The relative effect of 2,3-diphosphoglycerate on the oxygen affinity of fetal and adult hemoglobin in whole blood. Experientia 28, 1480–1481 (1972). https://doi.org/10.1007/BF01957865

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  • DOI: https://doi.org/10.1007/BF01957865

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