Impact Factor: 0.4

Open Access Published since April 20, 1989

Pteridines

Official Journal of the International Society of Pteridinology

ISSN: 2195-4720

Editor-in-chief: Dietmar Fuchs

About this journal

Objective
Pteridines is an open acess international quarterly journal dealing with all aspects of pteridine research. Pteridines are heterocyclic fused ring compounds involved in a wide range of biological functions from the color on butterfly wings to cofactors in enzyme catalysis to essential vitamins. Of the pteridines, 5,6,7,8-tetrahydrobiopterin is the necessary cofactor of several aromatic amino acid monoxygenases, the nitric oxide synthases and glyceryl ether monoxygenase (GEMO). Neopterin plays an essential role in the immune system and is an important biomarker in laboratory medicine for diseases such as HIV, cardiovascular disease, malignant tumors, among others.

Topics

Neopterin, dihydroneopterin, monapterin
Biopterin, tetrahydrobiopterin
Folates, antifolates, riboflavin
Phenylalanine, tyrosine, phenylketonuria, serotonin, adrenalin, noradrenalin, L-DOPA, dopamine, related biogenic amines
Phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, nitric oxide synthases (iNOS), alkylglycerol monooxygenase (AGMO), dihydropterin reductase, sepiapterin reductase
Homocysteine, mediators of inflammation, redox systems, iron

Article formats
Original articles, reviews, mini reviews, commentaries, opinions on controversial subjects

Your Benefits

Your benefits:

Unique interdisciplinary forum devoted to conjugated and unconjugated pteridines
Basic and clinical approach to the topic combining the fields of chemistry, biochemistry, clinical chemistry, and laboratory medicine
International, authoritative editors and reviewers boosting the prestige of published papers
Free language-correction services for authors from non-English speaking regions
Worldwide dissemination and unrestricted access to all published articles
Promotion of each published article
Secure archiving by De Gruyter and the independent archiving service Portico

Pteridines is the official journal of the International Society of Pteridinology (ISP).

History

Pteridines was founded in 1989 and has been continued at De Gruyter since 2013.

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Supplementary Materials

Topics

External Links

Volume 34 Issue 1

January 2023

Research Article

Open Access May 11, 2023

Effect of NB-UVB therapy on IL-6 and neopterin levels in patients with psoriasis

Emine Buket Sahin, Sonia Sanajou, Gözde Girgin, Tülin Akan, Terken Baydar

Article number: 20220048

More Download PDF

Abstract

Background Psoriasis is a chronic and non-transient disease with increased epidermal proliferation in the skin. Dysregulation of the immune system is an important factor in this pathology. Inflammation markers, pro-inflammatory cytokines, and immune cells are reported to be changed in psoriasis. Study design In the current cohort study, the possible changes in interleukin-6 (IL-6), neopterin levels, and kynurenine (Kyn) pathway in 42 psoriasis patients compared to 30 controls, and their change with narrow-band (NB) UVB treatment were investigated. Methodology IL-6 and serum neopterin levels were analyzed with ELISA kits. HPLC analyses were performed to detect urinary neopterin, serum Kyn, and tryptophan (Trp) levels. Results IL-6 levels were lower, while Kyn levels and the Kyn-to-Trp ratio were higher in psoriasis patients compared to control subjects ( p < 0.01, all). Conclusion Narrow-band ultraviolet B (NB-UVB) treatment decreased Psoriasis Area and Severity Index (PASI) scores and increased urinary neopterin levels of the patients (both, p < 0.01). Serum neopterin was correlated with Kyn and Kyn/Trp levels before and after NB-UVB treatment ( p < 0.05, all). These findings point out that the measured parameters might be considered to support the PASI score in both diagnosis and prognosis of psoriasis rather than evaluating the severity of the disease.

Review Article

Open Access February 24, 2023

The advent of phyllobilins as bioactive phytochemicals – natural compounds derived from chlorophyll in medicinal plants and food with immunomodulatory activities

Angelika M. Vollmar, Simone Moser

Article number: 20220047

More Download PDF

Abstract

The degradation of the green plant pigment chlorophyll has fascinated chemists and biologists alike over the last few decades. Bioactivities of the compounds formed in this biochemical degradation pathway, however, have only come to light recently. These natural compounds that are formed from chlorophyll during plant senescence are now called phyllobilins. In this review, we shortly discuss chlorophyll degradation and outline the so-far known bioactivities of selected phyllobilins (phylloleucobilin, dioxobilin-type phylloleucobilin, and phylloxanthobilin), and we also highlight the recently discovered immunomodulatory effects of a yellow phylloxanthobilin.

Volume 28 (2017)

Volume 27 (2016)

Volume 26 (2015)

Volume 25 (2014)

Volume 24 (2013)

Volume 23 (2012)

Issue 1

Volume 22 (2011)

Issue 1

Volume 21 (2010)

Issue 1

Volume 20 (2009)

Issue 1

Volume 19 (2008)

Issue 1

Volume 18 (2007)

Issue 1

Volume 17 (2006)

Volume 16 (2005)

Volume 15 (2004)

Volume 14 (2003)

Volume 13 (2002)

Volume 12 (2001)

Volume 11 (2000)

Volume 10 (1999)

Volume 9 (1998)

Volume 8 (1997)

Volume 7 (1996)

Volume 6 (1995)

Volume 5 (1994)

Volume 4 (1993)

Volume 3 (1991)

Volume 2 (1990)

Volume 1 (1989)

Journal Impact Factor	0.4	2022, Journal Citation Reports (Clarivate, 2023)
5-year Journal Impact Factor	0.8	2022, Journal Citation Reports (Clarivate, 2023)
Journal Citation Indicator	0.12	2022, Journal Citation Reports (Clarivate, 2023)
CiteScore	1.2	2022, Scopus (Elsevier B.V., 2023)
SCImago Journal Rank	0.175	2022, SJR (Scimago Lab, 2023; Data Source: Scopus)
Source Normalized Impact per Paper	0.143	2022, CWTS Journal Indicators (CWTS B.V., 2023; Data Source: Scopus)
Index Copernicus Value	151.81

More information about journal rankings

Submit

MANUSCRIPTS
Pteridines encourages the submission of both substantial full-length bodies of work and shorter manuscripts that report novel findings. There are no specific length restrictions for the overall manuscript or individual sections; however, we urge the authors to present and discuss their findings in a concise and accessible manner.

All submissions must be made via online submission system Editorial Manager. In case of problems, please contact the Managing Editor of this journal (jedrzej.daszkiewicz@degruyter.com).

For detailed information, please see Instruction for Authors.

EDITORIAL POLICY
Unpublished material: Submission of a manuscript implies that the work described is not copyrighted, published or submitted elsewhere, except in abstract form. The corresponding author should ensure that all authors approve the manuscript before its submission.
Ethical conduct of research: The authors must describe and confirm safeguards to meet ethical standards when applicable. See Editorial Policy for details.
Conflict of interest: When authors submit a manuscript, they are responsible for recognizing and disclosing financial and/or other conflicts of interest that might bias their work and/or could inappropriately influence his/her judgment. If no specified acknowledgement is given, the Editors assume that no conflict of interest exists. Authors are encouraged to fill in the ICMJE Conflicts of Interest Form (available here) and send it in the electronic format to the Managing Editor.
Copyright: All authors retain copyright, unless – due to their local circumstances – their work is not copyrighted. The copyrights are governed by the Creative-Commons Attribution Only license (CC-BY) which is compliant with Plan-S. We may also publish a paper under CC-BY-NC-ND license on author's request. The corresponding author grants the journal the license to use of the article, by signing the License To Publish. Scanned copy of license should be sent to the journal, as soon as possible.
Authorship: Authorship should be limited to those who have made a significant contribution to the conception, design, execution, or interpretation of the reported study. All those who have made significant contributions should be listed as co-authors. Where there are others who have participated in certain substantive aspects of the research project, they should be named in an Acknowledgement section. The corresponding author should ensure that all appropriate co-authors (according to the above definition) and no inappropriate co-authors are included in the author list of the manuscript, and that all co-authors have seen and approved the final version of the paper and have agreed to its submission for publication.
Peer Review process: Our standard policy requires each paper to be reviewed by at least two Referees and the peer-review process is single-blind. The Editors reserve the right to decline the submitted manuscript without review, if the studies reported are not sufficiently novel or important to merit publication in the journal. Manuscripts deemed unsuitable (insufficient originality or of limited interest to the target audience) are returned to the author(s) without review. The Editor seeks advice from experts in the appropriate field. Research articles and communications are refereed by a minimum of two reviewers, review papers by at least three. Authors are requested to suggest persons competent to review their manuscript. However, please note that this will be treated only as a suggestion, and the final selection of reviewers is exclusively the Editor's decision. The final decision of acceptance in made by Managing Editor or, in case of conflict, by the Editor-in-Chief.
Scientific Misconduct: This journal publishes only original manuscripts that are not also published or going to be published elsewhere. Multiple submissions/publications, or redundant publications (re-packaging in different words of data already published by the same authors) will be rejected. If they are detected only after publication, the journal reserves the right to publish a Retraction Note. In each particular case Editors will follow COPE’s Core Practices and implement the advices.

Editorial

Editor-in-Chief
Prof. Dr. Dietmar Fuchs (Division of Biological Chemistry, Innsbruck Medical University, Innsbruck, Austria)

Editorial Board
Prof. Dr. Terken Baydar (Department of Toxicology, Hacettepe University, Ankara, Turkey)
Prof. Dr. Nenad Blau (Department of General Pediatrics, University Children's Hospital, Heidelberg, Germany)
Prof. Dr. Keith Channon (John Radcliffe Hospital, University of Oxford, Oxford, UK)
Prof. Dr. Basak Engin (Department of Toxicology, Gazi University, Ankara, Turkey)
Prof. Dr. Steven P. Gieseg (Free Radical Biochemistry Laboratory, University of Canterbury, Christchurch, New Zealand)
Dr. Viola Groehn (API Synthesis & Development, Schaffhausen, Switzerland)
Prof. Dr. Steven S. Gross (Joan and Sanford I. Weill Medical School, Cornell University, New York, USA)
Prof. Dr. Hiroshi Ichinose (Tokyo Institute of Technology, Fujita Health University School of Medicine, Yokohama, Japan)
Prof. Dr. Greg Kapatos (Wayne State University School of Medicine, Detroit, USA)
Dr. Piotr Koslinski (Department of Toxicology, Nicolaus Copernicus University, Torun, Poland)
Dr. Katharina Kurz (Department of Internal Medicine, Innsbruck Medical University, Innsbruck, Austria)
Prof. Dr. Aurora Martinez (Department of Biomedicine, University of Bergen, Bergen, Norway)
Prof. Dr. Bohuslav Melichar (Department of Oncology, Palacký University Medical School, Olomouc, Czech Republic)
Dr. Vojtech Parrak (NsP sv Cyrila a Metoda, Petrzalka, Bratislava, Slovakia)
Prof. Dr. Godefridus Peters (VU University Hospital, Amsterdam, The Netherlands)
Prof. Dr. Gilbert Reibnegger (Institute of Physiological Chemistry, Graz Medical University, Graz, Austria)
Prof. Dr. Haruro Shintaku (Department of Pediatrics, Osaka City Medical School, Osaka, Japan)
Prof. Dr. Knut Teigen (Department of Biochemistry and Molecular Biology, University of Bergen, Bergen, Norway)
Prof. Dr. Anders H. Thomas (Department of Chemistry, Universidad Nacional de La Plata, La Plata, Argentina)
Prof. Dr. Aristidis Michael Tsatsakis (Department of Forensic Sciences and Toxicology, University of Crete Medical School, Heraklion, Greece)
Prof. Dr. Guenter Weiss (Department of Internal Medicine, Innsbruck Medical University, Innsbruck, Austria)
Prof. Dr. Ernst R. Werner (Division of Biological Chemistry, Innsbruck Medical University, Innsbruck, Austria)
Prof. Dr. Jeongbin Yim (Department of Microbiology, Seoul National University, Seoul, South Korea)

Language Editors
Eileen ABLONDI, Harvard Medical School, USA
Dr Kate Grayson (University of Bristol, UK)
Dr Laura McVeigh (University of New South Wales, Australia)
Dr Morgan Milton (RTI International, USA)
Zandile Nare (University of Edinburgh, UK)

Associate Editor
Qian (Kevin) Liu M.D. (Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China)

Editorial Office
Publisher
DE GRUYTER Poland
Bogumiła Zuga 32A Str.
01-811 Warsaw, Poland
T: +48 22 701 50 15

Editorial Contact
Jędrzej Daszkiewicz, Managing Editor
Jedrzej.Daszkiewicz@degruyter.com

(Deutsch)

Type: Journal
Language: English
Publisher: De Gruyter
First published: April 20, 1989
Publication Frequency: 1 Issue per Year
Audience: Researchers in the fields of chemistry, biochemistry, clinical biochemistry, metabolic disorders, clinical chemistry, clinical immunology, immunology, laboratory medicine, biology, molecular biology, molecular medicine, nutrition, phytomedicine