The 2023 MDPI Annual Report has
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14 pages, 1892 KiB  
Article
Associations between PM2.5 Components and Mortality of Ischemic Stroke, Chronic Obstructive Pulmonary Disease and Diabetes in Beijing, China
by Hao Feng, Yisen Yang, Hong Ye, Jing Xu, Meiduo Zhao, Ye Jin and Shuyang Zhang
Toxics 2024, 12(6), 381; https://doi.org/10.3390/toxics12060381 - 23 May 2024
Abstract
Ischemic stroke (IS), chronic obstructive pulmonary disease (COPD) and diabetes mellitus (DM) account for a large burden of premature deaths. However, few studies have investigated the associations between fine particular matter (PM2.5) components and mortality of IS, COPD and DM. We [...] Read more.
Ischemic stroke (IS), chronic obstructive pulmonary disease (COPD) and diabetes mellitus (DM) account for a large burden of premature deaths. However, few studies have investigated the associations between fine particular matter (PM2.5) components and mortality of IS, COPD and DM. We aimed to examine these associations in Beijing, China. Data on daily mortality, air pollutants and meteorological factors from 2008 to 2011 in Beijing were collected. Daily concentrations of five PM2.5 components, namely, sulfate ion (SO42−), ammonium ion (NH4+), nitrate ion (NO3), organic matter (OM) and black carbon (BC), were obtained from the Tracking Air Pollution (TAP) database in China. The association between PM2.5 components and daily deaths was explored using a quasi-Poisson regression with the distributed lag nonlinear model (DLNM). The average daily concentrations of SO42−, NH4+, NO3, OM and BC were 11.24, 8.37, 12.00, 17.34 and 3.32 μg/m3, respectively. After adjusting for temperature, relative humidity, pressure, particulate matter less than 10 μm in aerodynamic diameter (PM10), nitrogen dioxide (NO2) and sulfur dioxide (SO2), an IQR increase in OM at lag day 2 and lag day 6 was associated with an increased DM mortality risk (RR 1.038; 95% CI: 1.005–1.071) and COPD mortality risk (RR 1.013; 95% CI: 1.001–1.026). An IQR increase in BC at lag day 0 and lag day 6 was associated with increased COPD mortality risk (RR 1.228; 95% CI: 1.017–1.48, RR 1.059; 95% CI: 1.001–1.121). Cumulative exposure to SO42− and NH4+ was associated with an increased mortality risk for IS, with the highest effect found for lag of 0–7 days (RR 1.085; 95% CI: 1.010–1.167, RR 1.083; 95% CI: 1.003–1.169). These effects varied by sex and age group. This study demonstrated associations of short-term exposure to PM2.5 components with increased risk of IS, COPD and DM mortality in the general population. Our study also highlighted susceptible subgroups. Full article
(This article belongs to the Section Air Pollution and Health)
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15 pages, 6037 KiB  
Article
Oyster Peptides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis via Modulating the Gut Microbiota and Inhibiting the TLR4/NF-κB Pathway
by Haixiang Guo, Wenyin Xie, Zhonghao Ji, Bingbing Wang, Wenzhi Ren, Wei Gao and Bao Yuan
Nutrients 2024, 16(11), 1591; https://doi.org/10.3390/nu16111591 - 23 May 2024
Abstract
Ulcerative colitis (UC) is an inflammatory bowel disease with an increasing prevalence year over year, and the medications used to treat patients with UC clinically have severe side effects. Oyster peptides (OPs) have anti-inflammatory and antioxidant properties as functional foods that can alleviate [...] Read more.
Ulcerative colitis (UC) is an inflammatory bowel disease with an increasing prevalence year over year, and the medications used to treat patients with UC clinically have severe side effects. Oyster peptides (OPs) have anti-inflammatory and antioxidant properties as functional foods that can alleviate a wide range of inflammatory conditions. However, the application of oyster peptides in ulcerative colitis is not well studied. In this work, an animal model of acute colitis was established using 3% dextran sulfate sodium (DSS), and the impact of OP therapy on colitis in mice was examined. Supplementing with OPs prevented DSS-induced colitis from worsening, reduced the expression of oxidative stress and inflammatory markers, and restored the intestinal barrier damage caused by DSS-induced colitis in mice. The 16S rDNA results showed that the OP treatment improved the gut microbiota structure of the UC mice, including increasing microbial diversity, increasing beneficial bacteria, and decreasing harmful bacteria. In the UC mice, the OP therapy decreased the relative abundance of Family_XIII_AD3011_group and Prevotella_9 and increased the relative abundance of Alistipes. In conclusion, OP treatment can inhibit the TLR4/NF-κB pathway and improve the intestinal microbiota in UC mice, which in turn alleviates DSS-induced colitis, providing a reference for the treatment of clinical UC patients. Full article
18 pages, 9164 KiB  
Article
Enhancing Photovoltaic Performance with BaTiO3/MWCNTs Composite Photoelectrodes in Dye-Sensitized Solar Cells
by Carlos Armando Polo Bravo, Brayan Yeraldyn Caceres Osnayo, Jesús Alfredo Chacaltana García, Jesús Plácido Medina Salas, Francisco Gamarra Gómez, Hugo Alfredo Torres Muro, Alberto Bacilio Quispe Cohaila, Ramalinga Viswanathan Mangalaraja and Elisban Juani Sacari Sacari
Crystals 2024, 14(6), 489; https://doi.org/10.3390/cryst14060489 - 23 May 2024
Abstract
Dye-sensitized solar cells (DSSCs) have attracted renewed research interest as a potential low-cost substitute for conventional silicon photovoltaics. This work aims to improve the photovoltaic performance of the DSSCs by incorporating multi-walled carbon nanotubes (MWCNTs) into the BaTiO3 photoelectrode. The pure BaTiO [...] Read more.
Dye-sensitized solar cells (DSSCs) have attracted renewed research interest as a potential low-cost substitute for conventional silicon photovoltaics. This work aims to improve the photovoltaic performance of the DSSCs by incorporating multi-walled carbon nanotubes (MWCNTs) into the BaTiO3 photoelectrode. The pure BaTiO3 and BaTiO3/MWCNT nanocomposites were sensitized with N719 dye and fabricated into solar cell devices for testing. The structural characterization confirmed the successful formation of the nanocomposite with an optimal dispersion at 6% of MWCNT incorporation, beyond which agglomeration effects manifested. The optical analysis verified the modulation of defect states and bandgap engineering induced by the MWCNT network. The morphological studies revealed irregular nanoparticle clusters with embedded nanotubes. Solar cell testing under AM1.5G-simulated sunlight demonstrated a peak power conversion efficiency of 4.044% for 6% of MWCNT doping, constituting a 6-fold increment versus pure BaTiO3 (0.693%). It originated from the simultaneous enhancements in the open-circuit voltage and short-circuit current enabled by the favorable band structure alterations and percolation-assisted charge transport. However, further increasing MWCNT content deteriorated the device metrics, owing to emerging limitations like trapping. The rational integration of multi-walled carbon nanotubes with lead-free ferroelectric metal oxides can contribute to the development of emerging organic-inorganic hybrid solar platforms. Full article
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21 pages, 2728 KiB  
Article
Wearable-Based Integrated System for In-Home Monitoring and Analysis of Nocturnal Enuresis
by Sangyeop Lee, Junhyung Moon, Yong Seung Lee, Seung-chul Shin and Kyoungwoo Lee
Sensors 2024, 24(11), 3330; https://doi.org/10.3390/s24113330 - 23 May 2024
Abstract
Nocturnal enuresis (NE) is involuntary bedwetting during sleep, typically appearing in young children. Despite the potential benefits of the long-term home monitoring of NE patients for research and treatment enhancement, this area remains underexplored. To address this, we propose NEcare, an in-home monitoring [...] Read more.
Nocturnal enuresis (NE) is involuntary bedwetting during sleep, typically appearing in young children. Despite the potential benefits of the long-term home monitoring of NE patients for research and treatment enhancement, this area remains underexplored. To address this, we propose NEcare, an in-home monitoring system that utilizes wearable devices and machine learning techniques. NEcare collects sensor data from an electrocardiogram, body impedance (BI), a three-axis accelerometer, and a three-axis gyroscope to examine bladder volume (BV), heart rate (HR), and periodic limb movements in sleep (PLMS). Additionally, it analyzes the collected NE patient data and supports NE moment estimation using heuristic rules and deep learning techniques. To demonstrate the feasibility of in-home monitoring for NE patients using our wearable system, we used our datasets from 30 in-hospital patients and 4 in-home patients. The results show that NEcare captures expected trends associated with NE occurrences, including BV increase, HR increase, and PLMS appearance. In addition, we studied the machine learning-based NE moment estimation, which could help relieve the burdens of NE patients and their families. Finally, we address the limitations and outline future research directions for the development of wearable systems for NE patients Full article
(This article belongs to the Section Wearables)
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30 pages, 1261 KiB  
Review
Merits and Demerits of Machine Learning of Ferroelectric, Flexoelectric, and Electrolytic Properties of Ceramic Materials
by Kyuichi Yasui
Materials 2024, 17(11), 2512; https://doi.org/10.3390/ma17112512 - 23 May 2024
Abstract
In the present review, the merits and demerits of machine learning (ML) in materials science are discussed, compared with first principles calculations (PDE (partial differential equations) model) and physical or phenomenological ODE (ordinary differential equations) model calculations. ML is basically a fitting procedure [...] Read more.
In the present review, the merits and demerits of machine learning (ML) in materials science are discussed, compared with first principles calculations (PDE (partial differential equations) model) and physical or phenomenological ODE (ordinary differential equations) model calculations. ML is basically a fitting procedure of pre-existing (experimental) data as a function of various factors called descriptors. If excellent descriptors can be selected and the training data contain negligible error, the predictive power of a ML model is relatively high. However, it is currently very difficult for a ML model to predict experimental results beyond the parameter space of the training experimental data. For example, it is pointed out that all-dislocation-ceramics, which could be a new type of solid electrolyte filled with appropriate dislocations for high ionic conductivity without dendrite formation, could not be predicted by ML. The merits and demerits of first principles calculations and physical or phenomenological ODE model calculations are also discussed with some examples of the flexoelectric effect, dielectric constant, and ionic conductivity in solid electrolytes. Full article
17 pages, 8974 KiB  
Article
Garnet Geochemistry of Pertek Skarns (Tunceli, Turkey) and U-Pb Age Findings
by Ayşe Didem Kilic, Nevin Konakci and Ahmet Sasmaz
Minerals 2024, 14(6), 539; https://doi.org/10.3390/min14060539 (registering DOI) - 23 May 2024
Abstract
The Fe skarn and vein-type Cu mineralization types are common in the Eastern Taurus Mountains. This study aims to determine the U-Pb geochronology of garnets of varying sizes within the skarn zone developed at the quartz diorite–marble contact zone in Ayazpınar, Pertek District, [...] Read more.
The Fe skarn and vein-type Cu mineralization types are common in the Eastern Taurus Mountains. This study aims to determine the U-Pb geochronology of garnets of varying sizes within the skarn zone developed at the quartz diorite–marble contact zone in Ayazpınar, Pertek District, Tunceli Province, Turkey. Additionally, this study aims to determine the age of the skarnization and the types of inclusion minerals in the garnets. Faulting and magma emplacement along the thrust plane caused mineralization in the Eastern Taurus Mountains, especially at the marble and quartz diorite contact zone between the cities of Elazığ and Tunceli. The greenish garnets found in the Ayazpınar deposit are characteristic of distal skarns, while red or brown Pertek garnets are observed in the proximal skarns. The garnets typically feature a core–rim texture. The cores of the garnet crystals are large, reddish in color, and have a high REE (Ce, Pr) content. Moreover, the cores have higher Fe and lower Al ratios, alongside higher La, Ce, and Pr contents, than the rims. We propose that the compositional differences between the rims and the cores reflect the transition from oxidized REE- and Fe3+-rich liquids to liquids with lower REE and Fe3+ contents, producing the differences in the garnet colors. Green garnets show lower REE contents than brown garnets with Fe-rich cores. The skarn under study includes the following successively formed zones: diorite → epidote skarn → garnet–magnetite → pyrite–garnet–magnetite → calcite carbonate. Diopside, magnetite, and hematite, including small grains, are surrounded or enveloped by garnets. The U-Pb age of the mineralization is 74.1 ± 5 Ma, indicating that the mineralization occurred concurrently with the intrusion settlement. Full article
(This article belongs to the Section Mineral Geochemistry and Geochronology)
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24 pages, 6158 KiB  
Article
Computational Discovery of Novel Imidazole Derivatives as Inhibitors of SARS-CoV-2 Main Protease: An Integrated Approach Combining Molecular Dynamics and Binding Affinity Analysis
by Benjamin Ayodipupo Babalola and Abayomi Emmanuel Adegboyega
COVID 2024, 4(6), 672-695; https://doi.org/10.3390/covid4060046 - 23 May 2024
Abstract
One of the most pressing challenges associated with SARS treatment is the emergence of new variants that may be transmissible, causing more severe disease or being resistant to the current standard of treatment. This study aimed to identify potential drug candidates from novel [...] Read more.
One of the most pressing challenges associated with SARS treatment is the emergence of new variants that may be transmissible, causing more severe disease or being resistant to the current standard of treatment. This study aimed to identify potential drug candidates from novel imidazole derivatives against SARS-CoV-2 main protease (Mpro), a crucial drug target for treating viral infection, using a computational approach that integrated molecular docking and dynamics simulation. In this study, we utilized AutoDock Vina within the PyRx workspace for molecular docking analysis to explore the inhibitory effects of the compounds on the Mpro, a drug target for SARS-CoV-2. The ADMET properties of these compounds, including absorption, distribution, metabolism, excretion, and toxicity, were evaluated using the SwissADME and ADMETLab servers. Each of the 18 compounds that were tested demonstrated strong binding affinities towards Mpro, with imidazolyl–methanone C10 showing the most significant binding affinity. Moreover, pyridyl–imidazole C5, thiophenyl–imidazole C1, and quinoline–imidazole C14 displayed binding affinities of −8.3, −8.2, and −7.7 Kcal/mol, respectively. These compounds interacted with specific amino acid residues (HIS A:41—CYS A:145) within the Mpro protein. To assess the stability of the ligand with the best binding affinity, molecular dynamics (MD) simulations were conducted using Schrodinger software, which revealed its stability over the simulation period. The study provides valuable insights into the potential of imidazole derivatives as SARS-CoV-2 Mpro inhibitors. All compounds including C10 display promising characteristics and hold potential as drug candidates for SARS-CoV-2. However, further optimization and experimental validation of these compounds are necessary to advance their development as effective therapeutics against viral infections. Full article
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14 pages, 2790 KiB  
Article
Closing the Diagnostic Gap in Encephalitis and Acute Disseminated Encephalomyelitis through Digital Case Classification and Viral Metagenomics
by Patrick E. Obermeier, Xiaolin Ma, Albert Heim and Barbara A. Rath
Microbiol. Res. 2024, 15(2), 900-913; https://doi.org/10.3390/microbiolres15020059 - 23 May 2024
Abstract
Encephalitis and acute disseminated encephalomyelitis (ADEM) are often caused or triggered by viruses—but the specific pathogen commonly remains unidentified in routine care. We explored the use of viral metagenomic next-generation sequencing (mNGS) in addition to PCR testing of non-invasive stool samples to see [...] Read more.
Encephalitis and acute disseminated encephalomyelitis (ADEM) are often caused or triggered by viruses—but the specific pathogen commonly remains unidentified in routine care. We explored the use of viral metagenomic next-generation sequencing (mNGS) in addition to PCR testing of non-invasive stool samples to see if unbiased testing could potentially increase diagnostic yield. To identify specific clinical cases at the point of care, we took advantage of a previously published digital app allowing instant clinical case classification based on consensus case criteria, the VACC-Tool. This hospital-based prospective digital surveillance program assessed 100 pediatric patients (mean age: 11 years, range: 0.15–17.85; 49% male) with case-confirmed encephalitis and/or ADEM. Analysis of case classification at the point of care revealed that in routine care, 96% of confirmed encephalitis/ADEM cases had been missed. Overall agreement of routine care diagnoses with digital encephalitis/ADEM case classification was <50%. Also in routine care, only 13% of cases held a virus-related diagnosis, i.e., herpesvirus (n = 8) and enterovirus infection (n = 5). Use of mNGS increased the yield of virus detection by 77% (n = 23 virus hits). Specifically, mNGS identified 10 additional virus species beyond herpes- and enteroviruses. Of the additional 23 virus hits detected with mNGS, PCR confirmation was possible post hoc in 14 cases (61%). Linking digital case classification, mNGS, and PCR testing may not be feasible in routine care at this point but may help to provide hints to the pathogenesis of encephalitis/ADEM in childhood, warranting further research and exploration. Full article
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19 pages, 1114 KiB  
Article
The Detection of Propionate Utilization by Bacteria Isolated from a Plastic Recycling Site
by Shuyan Wu, Pornchanok Subharat, Faith Palevich, John Mills and Gale Brightwell
Appl. Microbiol. 2024, 4(2), 856-874; https://doi.org/10.3390/applmicrobiol4020059 - 23 May 2024
Abstract
(1) The study aims to utilize a reported approach for culturing mesophilic bacteria from a plastic waste environment; (2) The work revived mesophilic microbial population from an aged PET recycling site using a culture-based approach, and determined the purified isolates in genus level [...] Read more.
(1) The study aims to utilize a reported approach for culturing mesophilic bacteria from a plastic waste environment; (2) The work revived mesophilic microbial population from an aged PET recycling site using a culture-based approach, and determined the purified isolates in genus level in 16S identification; (3) A total of 59 bacterial isolates were obtained, in which microbial species, including Pseudomonas spp, Rhodococcus spp, and Burkholderia spp were identified as abundance. It was observed that the surviving microbes favoured sodium propionate as a short-chain carbon source for growth, rather than the intended plastic substrate, PET. The preference of sodium propionate utilization by several bacterial isolates, including 5601W (detected as Rhodococcus spp.), 5601Y, 7801, and 7802 (detected as Burkholderia spp.), was confirmed through growth curve analysis and cell enumeration conducted in a medium where sodium propionate served as the sole carbon source.; (4) The microbial demonstration revealed the metabolic complex of microbial communities in the environment and indicated the challenges associated with bacterial isolation from environments with accumulated plastic waste. Full article
10 pages, 679 KiB  
Article
Serological and Molecular Survey of Babesia ovis in Healthy Sheep in Türkiye
by Mehmet Bozan, Mehmet Can Ulucesme, Arda Eyvaz, Onur Ceylan, Ferda Sevinc, Munir Aktas and Sezayi Ozubek
Parasitologia 2024, 4(2), 162-171; https://doi.org/10.3390/parasitologia4020014 - 23 May 2024
Abstract
Babesiosis, caused by Babesia ovis, is a major seasonal issue in sheep, particularly in countries like Türkiye with high Rhipicephalus bursa tick populations. Previous studies employing various methods such as microscopy, serology, or molecular techniques have reported different epidemiological data [...] Read more.
Babesiosis, caused by Babesia ovis, is a major seasonal issue in sheep, particularly in countries like Türkiye with high Rhipicephalus bursa tick populations. Previous studies employing various methods such as microscopy, serology, or molecular techniques have reported different epidemiological data concerning ovine babesiosis. Addressing this knowledge gap, our study employed a combined nested PCR (nPCR)/indirect ELISA (iELISA) approach, analyzing blood samples collected from 414 sheep between April and July 2023 using both techniques. nPCR amplified the 18S ribosomal RNA gene of B. ovis and determined a molecular prevalence of 1.9%. Conversely, serological testing using iELISA targeted the BoSA1 antigen and revealed a significantly higher positivity rate of 59.9% for anti-B. ovis antibodies. The temporary presence of Babesia after recovery reduces nPCR sensitivity, resulting in lower molecular prevalence. However, even if Babesia is not present in the host, anti-B. ovis antibodies remain in the serum for a long time and can be detected serologically. Our study underscores the necessity of concurrently employing molecular and serological methods for an accurate assessment of B. ovis prevalence. It highlights the importance of comprehensive epidemiological approaches for effective disease management in sheep populations. Full article
12 pages, 388 KiB  
Review
Instruments for Evaluating the Nutritional Status of Cancer Patients Undergoing Antineoplastic Treatment: A Scoping Review
by Erik Medina Cruz, Natacha Palenzuela Luis, Natalia Rodríguez Novo, Miriam González Suarez, Raquel Casas Hernández and María Mercedes Novo Muñoz
Nurs. Rep. 2024, 14(2), 1312-1323; https://doi.org/10.3390/nursrep14020099 - 23 May 2024
Abstract
The use of validated tools to evaluate the nutritional status of the cancer patient provides guaranteed precision and reliability in their nutritional evaluation, ensuring that the information is accurate and reflects the patient's situation. The aim of this study was to identify the [...] Read more.
The use of validated tools to evaluate the nutritional status of the cancer patient provides guaranteed precision and reliability in their nutritional evaluation, ensuring that the information is accurate and reflects the patient's situation. The aim of this study was to identify the valid and reliable instruments in the evaluation of the nutritional status of cancer patients with a diagnosis of solid tumor undergoing antineoplastic treatment (chemotherapy and/or immunotherapy). A scoping review was conducted to search for original articles published in scientific journals in English, Spanish, or Portuguese in the past five years. In order to identify potentially relevant documents, searches were performed in the following databases: SCOPUS, WOS, CINAHL, MEDLINE, BVS, and PUBMED. DECS-MeSH descriptors and Boolean operators were used. In addition, the Arksey and O’Malley protocol, the Joanne Briggs Institute (JBI) method, and the flow chart of the Preferred Information Elements for Systematic Reviews and Meta-Analyses, known as PRISMA, were followed. The initial search strategy identified a total of 164 references, which were examined successively, leaving a final selection of ten studies. It was found that the most used instrument for nutritional evaluation was the Patient-Generated Subjective Global Assessment (PG-SGA). Other questionnaires also stood out such as the Mini Nutritional Assessment (MNA), the Malnutrition Universal Screening Tool (MUST), the Nutritional Risk Screening (NRS 2002), and the Functional Assessment of Anorexia/Cachexia Therapy (FAACT). The variation in the tools used ranges from subjective assessments to objective measurements, thus underlining the need for a comprehensive and individualized approach. Full article
11 pages, 220 KiB  
Article
Assistive Technology for Higher Education Students with Disabilities: A Qualitative Research
by Konstantinos Papadopoulos, Eleni Koustriava, Lisander Isaraj, Elena Chronopoulou, Flavio Manganello and Rafael Molina-Carmona
Digital 2024, 4(2), 501-511; https://doi.org/10.3390/digital4020025 - 23 May 2024
Abstract
The objective of this qualitative investigation is to identify the assistive technology recognized by students with disabilities and to determine the assistive technology (software apps and devices) they require both at university and at home. A total of forty-two students, comprising 20 males [...] Read more.
The objective of this qualitative investigation is to identify the assistive technology recognized by students with disabilities and to determine the assistive technology (software apps and devices) they require both at university and at home. A total of forty-two students, comprising 20 males and 22 females, were recruited from four different countries (Germany, Greece, Italy, and Spain) for participation in this study. The sample encompassed 10 students with visual impairments, 11 with hearing impairments, 11 with mobility impairments, and 10 with specific learning disabilities. Semi-structured interviews were conducted with the students either online or in person. Content analysis was employed to scrutinize the data obtained from these interviews. The outcomes of this analysis shed light on the assistive technology acknowledged, utilized, or desired by students with disabilities in both academic and domestic settings. The findings from this study carry practical implications for fostering inclusive and accessible education within higher education institutions, benefiting accessibility units/offices staff as well as teaching personnel. Full article
(This article belongs to the Special Issue Digital in 2024)
13 pages, 1837 KiB  
Article
Research on Stability Control of Distributed Drive Vehicle with Four-Wheel Steering
by Jiahao Zhang, Chengye Liu, Jingbo Zhao and Haimei Liu
World Electr. Veh. J. 2024, 15(6), 228; https://doi.org/10.3390/wevj15060228 - 23 May 2024
Abstract
The four-wheel steering distributed drive vehicle is a novel type of vehicle with independent control over the four-wheel angle and wheel torque. A method for jointly controlling the distribution of the wheel angle and torque is proposed based on this characteristic. Firstly, the [...] Read more.
The four-wheel steering distributed drive vehicle is a novel type of vehicle with independent control over the four-wheel angle and wheel torque. A method for jointly controlling the distribution of the wheel angle and torque is proposed based on this characteristic. Firstly, the two-degrees-of-freedom model and ideal reference model of four-wheel steering vehicle are established; then, the four-wheel steering controller and torque distribution controller are designed. The rear wheel angle is controlled by the feedforward controller and the feedback controller. The feedforward controller takes the side slip angle of the center of mass as the control target, and the feedback controller takes the yaw angle as the control target. Torque is controlled by two control layers, the additional yaw moment of the upper layer is calculated by the vehicle motion state and fuzzy control theory, and the lower layer distributes wheel torque through the road adhesion coefficient and wheel load. Finally, a simulation platform is established to verify the effectiveness of the proposed control algorithm. Full article
(This article belongs to the Special Issue Vehicle System Dynamics and Intelligent Control for Electric Vehicles)
19 pages, 3069 KiB  
Article
Free Riding of Vehicle Companies under Dual-Credit Policy: An Agent-Based System Dynamics Model
by Zhong Zhou and Yuqi Shen
World Electr. Veh. J. 2024, 15(6), 227; https://doi.org/10.3390/wevj15060227 - 23 May 2024
Abstract
The dual-credit policy promotes green transition in automobile companies. This paper investigates the dual-credit policy framework in the Chinese automotive industry, with a focus on the phenomenon of free riding. This occurs when traditional vehicle manufacturers within an alliance benefit from the excess [...] Read more.
The dual-credit policy promotes green transition in automobile companies. This paper investigates the dual-credit policy framework in the Chinese automotive industry, with a focus on the phenomenon of free riding. This occurs when traditional vehicle manufacturers within an alliance benefit from the excess credits generated by a transitioning vehicle company without fully committing to their own green transitioning. The focus of this study lies on an alliance constituted by a transitioning vehicle company in partnership with two traditional vehicle manufacturers, all interconnected via equity ties. Utilizing an agent-based system dynamics model, this study explores the strategic behaviors emerging from such credit collaborations and their consequent effects on operational efficiency and financial performance. The findings reveal that 1. free riding negatively impacts the transitioning company’s revenue but benefits the alliance by easing transition pressures and boosting collective performance; 2. stricter policies increase intra-alliance credit transfers and performance, while lower credit prices reduce transfer value and harm the transitioning company’s earnings. This study implies that transitioning vehicle companies with equity-linked partners can benefit from a nuanced understanding of how policy mechanisms interact with alliance dynamics under free riding. By adjusting credit transfer strategies in line with market conditions and policy trends, they can better navigate the dual-credit policy landscape, balancing individual profitability with the needs of the broader alliance and long-term sustainability goals. Full article
(This article belongs to the Special Issue New Energy Special Vehicle, Tractor and Agricultural Machinery)
17 pages, 3584 KiB  
Article
Community Attachment to AlUla Heritage Site and Tourists’ Green Consumption: The Role of Support for Green Tourism Development
by Ibrahim A. Elshaer, Mansour Alyahya, Alaa M. S. Azazz and Sameh Fayyad
Heritage 2024, 7(6), 2651-2667; https://doi.org/10.3390/heritage7060126 - 23 May 2024
Abstract
This study explores the interrelationship between community attachment in AlUla Heritage City (located in Saudi Arabia) and tourists’ green consumption practices, testing support for green tourism development as a mediator. The old historical city of AlUla, a significant city experiencing ongoing preservation and [...] Read more.
This study explores the interrelationship between community attachment in AlUla Heritage City (located in Saudi Arabia) and tourists’ green consumption practices, testing support for green tourism development as a mediator. The old historical city of AlUla, a significant city experiencing ongoing preservation and tourism development, represents an adequate context for exploring the link between community attachment and green tourism practices. This study employs a quantitative approach, including surveys with 328 local residents of AlUla. A structural equation modeling partial least square (PLS-SEM) analysis is conducted to explore the indirect influence of community attachment on tourists’ green consumption through the mediating role of support for green tourism development. The findings indicated a positive path from community attachment in AlUla to tourists’ tendencies toward green consumption behavior. Moreover, the mediating effects of support for green tourism development suggested that a deep sense of community attachment improves tourists’ support for green practices in the tourism sector. This study adds to the extended body of the literature on place attachment and green tourism by emphasizing the significance of community place attachment in stimulating tourists’ green consumption practices. Several practical implications for policymakers seeking to promote green tourism practices in heritage cities like AlUla are explored from the study results. Full article
(This article belongs to the Special Issue Heritage Tourism and Sustainable City Dynamics)
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18 pages, 463 KiB  
Article
Adherence, Disease Control, and Misconceptions Related to the Use of Inhalation Therapy in Patients with Obstructive Pulmonary Diseases: A Cross-Sectional Study
by Dejan Živanović, Jovan Javorac, Dejana Savić, Andrijana Mikić, Marija Jevtić, Miroslav Ilić, Violeta Kolarov, Ivana Minaković, Bela Kolarš, Mirjana Smuđa and Vesna Mijatović Jovin
Medicina 2024, 60(6), 853; https://doi.org/10.3390/medicina60060853 - 23 May 2024
Abstract
Background and Objectives: Inadequate treatment of asthma and chronic obstructive pulmonary disease (COPD) might have a negative impact on their progression. Inhalation therapy is the cornerstone of pharmacotherapy for these conditions. However, challenges such as low adherence, negative attitudes, and misconceptions about [...] Read more.
Background and Objectives: Inadequate treatment of asthma and chronic obstructive pulmonary disease (COPD) might have a negative impact on their progression. Inhalation therapy is the cornerstone of pharmacotherapy for these conditions. However, challenges such as low adherence, negative attitudes, and misconceptions about inhaled medications still persist, impeding effective disease management. This study aimed to evaluate adherence, ascertain the level of disease control in asthma and COPD, explore potential misconceptions surrounding inhalation therapy among patients with obstructive lung diseases and the general population in Vojvodina, and evaluate the reliability of newly developed questionnaires employed in the study. Materials and Methods: This cross-sectional study utilized a battery of questionnaires encompassing sociodemographic data, the Asthma Control Test (ACT), the COPD Assessment Test (CAT), along with two novel questionnaires—one for assessing adherence and another for analyzing attitudes toward inhalation therapy. Statistical analyses were conducted using SPSS software, version 25.0. Results: The average ACT score among patients with asthma was 17.31, while it was 19.09 for the CAT questionnaire among COPD patients. The composite score on the newly developed adherence assessment questionnaire was 2.27, exhibiting a reliability coefficient lower than recommended (α = 0.468). Significant statistical differences emerged among sample subgroups regarding attitudes and misconceptions toward inhalation therapy. The reliability coefficient for this questionnaire was deemed satisfactory (α = 0.767). Conclusions: Adherence rates were notably suboptimal in both subgroups of the studied population. The disease control levels were higher among asthma patients, while they exhibited less prevalent misconceptions regarding inhalation therapy compared to COPD patients and the healthy population. Full article
(This article belongs to the Section Pulmonary)
22 pages, 3671 KiB  
Article
Estimating Fire Radiative Energy Density with Repeat-Pass Aerial Thermal-Infrared Imaging of Actively Progressing Wildfires
by Alexander J. McFadden, Douglas A. Stow, Philip J. Riggan, Robert Tissell, John O’Leary and Henry Scharf
Fire 2024, 7(6), 179; https://doi.org/10.3390/fire7060179 - 23 May 2024
Abstract
Studies on estimating cumulative fire intensity from spreading wildland fires based on fire radiative energy density (FRED) have primarily been conducted through controlled experiments. The objective of this study was to assess the potential for estimating FRED for freely-burning wildfires at landscape scales. [...] Read more.
Studies on estimating cumulative fire intensity from spreading wildland fires based on fire radiative energy density (FRED) have primarily been conducted through controlled experiments. The objective of this study was to assess the potential for estimating FRED for freely-burning wildfires at landscape scales. Airborne thermal infrared image sequences collected 8 and 9 December 2017 during the Thomas Fire were used for surface temperature derivation and FRED estimation. Sensitivity of varying ambient temperatures, and a newly developed method that adjusts for ash radiances on fire radiative flux density (FRFD) and FRED estimates were tested. Pixel-level image classification was run to identify FRFD time sequences that were complete or incomplete because of cloud obscuration and provided the basis for an obscuration gap filling technique. Variations in estimated ambient temperature used to estimate FRFD had little impact on FRED estimates, while our ash adjustment led to notable differences. An exponential decay model characterized FRFD time sequences well, providing a basis for gap filling irregular sequences caused by atmospheric obscuration. FRED estimates were regressed on rate of spread (ROS) magnitudes and found to be positively and significantly correlated. FRED magnitudes were higher on 9 December when the Thomas Fire burned under higher wind speeds and lower relative humidity levels (Santa Ana weather conditions) than on 8 December. Full article
(This article belongs to the Special Issue Monitoring Wildfire Dynamics with Remote Sensing)
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13 pages, 4226 KiB  
Article
Monte Carlo Analysis for Evacuation in Multipurpose Event Spaces
by Adéla Snohová, Petr Kučera, Jiri Pokorny and Ales Bernatik
Fire 2024, 7(6), 178; https://doi.org/10.3390/fire7060178 - 23 May 2024
Abstract
This paper addresses the evacuation of people from multipurpose halls and introduces an innovative approach that uses a probabilistic model, specifically the Monte Carlo method, to analyse iterative evacuation processes. The aim is to explore how this modern technology can contribute to the [...] Read more.
This paper addresses the evacuation of people from multipurpose halls and introduces an innovative approach that uses a probabilistic model, specifically the Monte Carlo method, to analyse iterative evacuation processes. The aim is to explore how this modern technology can contribute to the development of effective and safe evacuation plans for mass events. The Monte Carlo method was applied to a specific example of a multipurpose hall that offers different configurations for events such as sports matches, concerts, or performances. The evacuation of people was analysed for two configurations: a hockey match with a capacity of 9500 people and a concert with a capacity of 11,000 people. In both cases, the total evacuation of people from the hall was analysed, and the evacuation time was evaluated when two parameters were changed: speed of movement and preference for door selection. The results of the simulations can provide valuable information for the design of effective safety measures in multipurpose halls and other similar multipurpose venues. This innovative approach to evacuation analysis allows for a comprehensive assessment of the evacuation process, identification of critical areas, and verification of the layout of the space. Full article
(This article belongs to the Special Issue Probabilistic Risk Assessments in Fire Protection Engineering)
27 pages, 392 KiB  
Article
Multiple Normalized Solutions to a Choquard Equation Involving Fractional p-Laplacian in RN
by Xin Zhang and Sihua Liang
Fractal Fract. 2024, 8(6), 310; https://doi.org/10.3390/fractalfract8060310 - 23 May 2024
Abstract
In this paper, we study the existence of multiple normalized solutions for a Choquard equation involving fractional p-Laplacian in RN. With the help of variational methods, minimization techniques, and the Lusternik–Schnirelmann category, the existence of multiple normalized solutions is obtained [...] Read more.
In this paper, we study the existence of multiple normalized solutions for a Choquard equation involving fractional p-Laplacian in RN. With the help of variational methods, minimization techniques, and the Lusternik–Schnirelmann category, the existence of multiple normalized solutions is obtained for the above problem. Full article
(This article belongs to the Special Issue Variational Problems and Fractional Differential Equations)
20 pages, 1654 KiB  
Article
Atmospheric Sound Propagation over Rough Sea: Numerical Evaluation of Equivalent Acoustic Impedance of Varying Sea States
by Andrea Vecchiotti, Teresa J. Ryan, Joseph F. Vignola and Diego Turo
Acoustics 2024, 6(2), 489-508; https://doi.org/10.3390/acoustics6020026 - 23 May 2024
Abstract
This work presents a numerical study on atmospheric sound propagation over rough water surfaces with the aim of improving predictions of sound propagation over long distances. A method for generating pseudorandom sea profiles consistent with sea wave spectra is presented. The proposed method [...] Read more.
This work presents a numerical study on atmospheric sound propagation over rough water surfaces with the aim of improving predictions of sound propagation over long distances. A method for generating pseudorandom sea profiles consistent with sea wave spectra is presented. The proposed method is suited for capturing the logarithmic nature of the energy distribution of the waves. Sea profiles representing fully developed seas for sea states 2, 3, 4, and 5 are generated from the Elfouhaily et al. (ECKV) sea wave spectra. Excess attenuation caused by refraction and surface roughness is predicted with a parabolic equation (PE) solver. A novel method for estimating equivalent effective impedance based on PE predictions at different sea states is presented. Parametric expressions using acoustic frequency and significant wave height are developed for effective surface impedances. In this work, sea surface roughness is on a scale comparable with the acoustic wavelength. Under this condition, the acoustic scattering is primarily incoherent. This work shows the limitations of using an equivalent surface impedance in such incoherent scattering cases. Full article
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22 pages, 1094 KiB  
Article
Fractional Second-Grade Fluid Flow over a Semi-Infinite Plate by Constructing the Absorbing Boundary Condition
by Jingyu Yang, Lin Liu, Siyu Chen, Libo Feng and Chiyu Xie
Fractal Fract. 2024, 8(6), 309; https://doi.org/10.3390/fractalfract8060309 - 23 May 2024
Abstract
The modified second-grade fluid flow across a plate of semi-infinite extent, which is initiated by the plate’s movement, is considered herein. The relaxation parameters and fractional parameters are introduced to express the generalized constitutive relation. A convolution-based absorbing boundary condition (ABC) is developed [...] Read more.
The modified second-grade fluid flow across a plate of semi-infinite extent, which is initiated by the plate’s movement, is considered herein. The relaxation parameters and fractional parameters are introduced to express the generalized constitutive relation. A convolution-based absorbing boundary condition (ABC) is developed based on the artificial boundary method (ABM), addressing issues related to the semi-infinite boundary. We adopt the finite difference method (FDM) for deriving the numerical solution by employing the L1 scheme to approximate the fractional derivative. To confirm the precision of this method, a source term is added to establish an exact solution for verification purposes. A comparative evaluation of the ABC versus the direct truncated boundary condition (DTBC) is conducted, with their effectiveness and soundness being visually scrutinized and assessed. This study investigates the impact of the motion of plates at different fluid flow velocities, focusing on the effects of dynamic elements influencing flow mechanisms and velocity. This research’s primary conclusion is that a higher fractional parameter correlates with the fluid flow. As relaxation parameters decrease, the delay effect intensifies and the fluid velocity decreases. Full article
23 pages, 2616 KiB  
Review
Lead-Free NaNbO3-Based Ceramics for Electrostatic Energy Storage Capacitors
by Sairatun Nesa Soheli, Zhilun Lu, Dongyang Sun and Islam Shyha
Ceramics 2024, 7(2), 712-734; https://doi.org/10.3390/ceramics7020047 - 23 May 2024
Abstract
The burgeoning significance of antiferroelectric (AFE) materials, particularly as viable candidates for electrostatic energy storage capacitors in power electronics, has sparked substantial interest. Among these, lead-free sodium niobate (NaNbO3) AFE materials are emerging as eco-friendly and promising alternatives to lead-based materials, [...] Read more.
The burgeoning significance of antiferroelectric (AFE) materials, particularly as viable candidates for electrostatic energy storage capacitors in power electronics, has sparked substantial interest. Among these, lead-free sodium niobate (NaNbO3) AFE materials are emerging as eco-friendly and promising alternatives to lead-based materials, which pose risks to human health and the environment, attributed to their superior recoverable energy density and dielectric breakdown strength. This review offers an insightful overview of the fundamental principles underlying antiferroelectricity and the applications of AFE materials. It underscores the recent advancements in lead-free NaNbO3-based materials, focusing on their crystal structures, phase transitions, and innovative strategies devised to tailor their electrostatic energy storage performance. Finally, this review delineates the prevailing challenges and envisages future directions in the realm of NaNbO3-based electrostatic energy storage capacitors, with the goal of fostering further advancements in this pivotal field. Full article
(This article belongs to the Special Issue Advances in Electronic Ceramics)
17 pages, 484 KiB  
Review
Role of Sport Vision in Performance: Systematic Review
by Andrea Buscemi, Flora Mondelli, Ilaria Biagini, Stella Gueli, Angela D'Agostino and Marinella Coco
J. Funct. Morphol. Kinesiol. 2024, 9(2), 92; https://doi.org/10.3390/jfmk9020092 - 23 May 2024
Abstract
Sport Vision is a speciality of multidisciplinary interest aimed at improving the performance of the visual system to achieve benefits in practiced sports, as well as in daily life and in preventive care. The type of training practiced by the athlete, his or [...] Read more.
Sport Vision is a speciality of multidisciplinary interest aimed at improving the performance of the visual system to achieve benefits in practiced sports, as well as in daily life and in preventive care. The type of training practiced by the athlete, his or her physical condition, cognitive level, and level of fatigue condition affects the speed of the reaction time and, consequently, the speed of motor response. Specific orthoptic exercises, the use of technological devices, the recovery of static and dynamic postural stability by using unstable platforms and the dual-task paradigm can help to achieve the expected results. The aim of this systematic review of Sport Vision was to assess the overall existing literature on Sport Vision, paying particular attention to the effects of visual training and its application in different sports and in rehabilitation and preventive settings. We analysed published English language studies about the role of sport vision in athletic performance from 1950 to 2023. We searched through the Medline database. The PRISMA 2020 checklist was used to assess the transparency and reproducibility of this review. The enrolled papers were evaluated with the Jadad Scale, Amstar 2 Scale and Newcastle–Ottawa Scale. 25 (16 studies, 5 reviews, 2 comments, 1 editorial, 1 descriptive paper) out of 476 studies met the inclusion criteria. Due to the variability in the age of the samples, the different techniques, the treatments among the participants in the studies and the finding of non-evaluable articles, a meta-analysis was not conducted. The limitations of this review are the single database research, the studies analyzed contain a non-statistically representative sample size and the lack of a control group. There is no standardized test to measure performance. It was shown that the development of visual skills can benefit athletes in injury prevention, and can lead to improved sports performance and motor function at any age, acquiring adaptive motor behaviour even when the visual system is impaired, due to task repetition and familiarity of the gesture. We intended to identify a multidisciplinary approach and a manual treatment scheme to optimize the circuitry involved in sport vision in order to increase the results that are achieved, but further studies will be needed to this end. Full article
(This article belongs to the Special Issue Biomechanics and Neuromuscular Control of Gait and Posture)

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