Semantic segmentation of remote sensing imagery stands as a fundamental task within the domains of both remote sensing and computer vision. Its objective is to generate a comprehensive pixel-wise segmentation map of an image, assigning a specific label to each pixel. This facilitates in-depth analysis and comprehension of the Earth’s surface. In this paper, we propose an approach for enhancing semantic segmentation performance by employing an ensemble of U-Net models with three different backbone networks: Multi-Axis Vision Transformer, ConvFormer, and EfficientNet. The final segmentation maps are generated through a geometric mean ensemble method, leveraging the diverse representations learned by each backbone network. The effectiveness of the base U-Net models and the proposed ensemble is evaluated on multiple datasets commonly used for semantic segmentation tasks in remote sensing imagery, including LandCover.ai, LoveDA, INRIA, UAVid, and ISPRS Potsdam datasets. Our experimental results demonstrate that the proposed approach achieves state-of-the-art performance, showcasing its effectiveness and robustness in accurately capturing the semantic information embedded within remote sensing images. Full article

Loquat (Eriobotrya japonica Lindl.), a non-climacteric fruit, is susceptible to physical and mechanical damage, as well as decay, especially after minimal processing, resulting in a short postharvest lifespan The objective of our study was to evaluate the impact of a cactus pear (OFI) mucilage-based edible coating enriched with glycerol and l-glutamine on the quality and nutraceutical value of minimally processed white-flesh Martorana loquat fruits during cold storage. After washing and processing the cladodes, mucilage was extracted, and two different coatings (EC1: 60% OFI mucilage, 40% glycerol; EC2: 67% OFI mucilage, 30% glycerol, 3% glutamine) were formulated and compared with an untreated sample (CTR). Our analyses covered various parameters, including color, total soluble solid content, titratable acidity, antioxidant activity, and total phenols. Additionally, sensory analysis was conducted and visual scores were obtained. The results suggest that the application of a cactus pear mucilage-based edible coating, supplemented with glycerol and L-glutamine, effectively preserves the quality attributes of minimally processed loquat fruits. Full article

This study of the strength and deformation of coal samples was triggered by the need to define the stress–strain characteristics of pillars during room and pillar mining in the shaft protective pillar at the ČSM Mine. It was probably the world’s deepest deployment of this mining method in a coal mine. In order to solve the bearing capacity of pillars, the dependence of coal strength on the slenderness ratio is used. For this reason, coal samples with different slenderness ratios were investigated. After considering the purpose of this research, slenderness ratios (width/height) of 1 to 7.7 were chosen. At the same time, the modulus of deformation as a function of the slenderness ratio was determined, and the vertical deformation of the pillars and the safety factor were calculated. Attention is also paid to the influence of sampling on the results of measured coal strengths. Full article

Hydra head formation depends on an organizing center in which Wnt/β-catenin signaling, that plays an inductive role, positively regulates Sp5 and Zic4, with Sp5 limiting Wnt3/β-catenin expression and Zic4 triggering tentacle formation. Using transgenic lines in which the HySp5 promoter drives eGFP expression in either the epidermis or gastrodermis, we show that Sp5 promoter activity is differentially regulated in each epithelial layer. In intact animals, epidermal HySp5:GFP activity is strong apically and weak along the body column, while in the gastrodermis, it is maximal in the tentacle ring region and maintained at a high level along the upper body column. During apical regeneration, HySp5:GFP is activated early in the gastrodermis and later in the epidermis. Alsterpaullone treatment induces a shift in apical HySp5:GFP expression towards the body column where it forms transient circular figures in the epidermis. Upon β-catenin(RNAi), HySp5:GFP activity is down-regulated in the epidermis while bud-like structures expressing HySp5:GFP in the gastrodermis develop. Sp5(RNAi) reveals a negative Sp5 autoregulation in the epidermis, but not in the gastrodermis. These differential regulations in the epidermis and gastrodermis highlight the distinct architectures of the Wnt/β-catenin/TCF/Sp5/Zic4 network in the hypostome, tentacle base and body column of intact animals, as well as in the buds and apical and basal regenerating tips. Full article

Human decision-making is increasingly supported by artificial intelligence (AI) systems. From medical imaging analysis to self-driving vehicles, AI systems are becoming organically embedded in a host of different technologies. However, incorporating such advice into decision-making entails a human rationalization of AI outputs for supporting beneficial outcomes. Recent research suggests intermediate judgments in the first stage of a decision process can interfere with decisions in subsequent stages. For this reason, we extend this research to AI-supported decision-making to investigate how intermediate judgments on AI-provided advice may influence subsequent decisions. In an online experiment (N = 192), we found a consistent bolstering effect in trust for those who made intermediate judgments and over those who did not. Furthermore, violations of total probability were observed at all timing intervals throughout the study. We further analyzed the results by demonstrating how quantum probability theory can model these types of behaviors in human–AI decision-making and ameliorate the understanding of the interaction dynamics at the confluence of human factors and information features. Full article

Lacquered brass objects are widely present in scientific and technical heritage collections. Localized atmospheric corrosion occurs on the metal when the coating fails to play its protective role. Although lacquered brass objects are not necessarily endangered by this phenomenon, the presence of dark, unpleasant corrosion spots alters the surface appearance, affecting the readability of the objects. Conservators are therefore frequently asked to clean these surfaces. We hereby present the results of a study conducted in the framework of the CleanLaB (Cleaning of Lacquered Brass) project at the Haute Ecole Arc of Neuchâtel for the cleaning of lacquered brass. This work investigates the effects of several gelled cleaning systems applied on artificially aged, lacquered brass samples to remove the corrosion products without affecting the integrity of the coating. The performance of complexing agents commonly used in conservation was compared on lacquered brass mock-ups coated with shellac resin by means of multiple non-invasive characterization and imaging techniques. The tests included conventional complexing agents like sodium citrate and disodium ethylenediaminetetraacetic acid, as well as a bio-originated system based on deferoxamine, a microbial metal chelator investigated as a green alternative in cleaning formulations. Full article

This review aims to highlight the main microbiological challenges faced in poultry transport and show the role of effective bacterial control during this process to ensure poultry health and meat safety and to reduce economic losses. Poultry infections are among the most frequent infections in production systems, manifesting themselves in hatcheries, farms, slaughterhouses, and during transport between these integration centers. Although the clinical symptoms of these infections can range from mild to severe, many of them can lead to irreversible conditions, resulting in death and compromising productive results. Bacteria are the main causative agents of these infections, although fungi, viruses, and protozoa may also be involved. During the transport of poultry from farms to slaughterhouses, poultry are very vulnerable to infectious conditions. Therefore, implementing effective antibacterial management, focused on professionals, transport crates, and transport vehicles, is essential to guarantee the survival and quality of poultry until the moment of slaughter. Full article

Automated ultrasonic testing (AUT) is a nondestructive testing (NDT) method widely employed in industries that hold substantial economic importance. To ensure accurate inspections of exclusive AUT data, expert operators invest considerable effort and time. While artificial intelligence (AI)-assisted tools, utilizing deep learning models trained on extensive in-laboratory B-scan images, whether they are augmented or synthetically generated, have demonstrated promising performance for automated ultrasonic interpretation, ongoing efforts are needed to enhance their accuracy and applicability. This is possible through the evaluation of their performance with experimental ultrasonic data. In this study, we introduced a real-world ultrasonic B-scan image dataset generated from proprietary recorded AUT data during industrial automated girth weld inspection in oil and gas pipelines. The goal of inspection in our dataset was detecting a common type of defect called lack of fusion (LOF). We experimentally evaluated deep learning models for automatic weld defect detection using this dataset. Our assessment covers the baseline performance of state-of-the-art (SOTA) models, including transformer-based models (DETR and Deformable DETR) and YOLOv8. Their flaw detection performance in ultrasonic B-scan images has not been reported before. The results show that, without heavy augmentations or architecture customization, YOLOv8 outperforms the other models with an F1 score of 0.814 on our test set. Full article

Western flower thrips, Frankliniella occidentalis (WFT), is one of the most destructive insect pests of vegetables and ornamental crops globally. Ultraviolet-C (UV-C) exposure has been shown to reduce populations of arthropod pests, including whiteflies and two-spotted spider mites, but has not been fully assessed for WFT. The goal of this study was to determine if UV-C radiance could be a viable strategy for inclusion in integrated pest management (IPM) programs for WFT. The objectives were to (1) assess the relationship among UV-C dose (irradiance × duration) and mortality of WFT adults and second instar larvae, (2) determine the effect of UV-C on WFT fecundity and egg hatch, and (3) assess the effect of the WFT lethal dose of UV-C on three WFT-prone ornamental plants. A UV-C dose is measured in Joules, which equals power (watts) × exposure time. A dose-dependent relationship between UV-C exposure and mortality of WFT larvae and adults was observed. At the doses of 0.98 and 0.68 J/cm² (5 and 4 min exposure, respectively), 50% of the larvae died within 24 and 48 h, respectively. The UV-C dose needed to achieve 50% mortality was higher for adults than larvae, occurring at 5.2 and 4.4 J/cm² (35 min and 25 min exposure, respectively) within 72 and 120 h, respectively. The number of eggs laid by surviving WFT subjected to UV-C treatment was less than by those that were untreated, and the egg-laying period was significantly shorter among those treated with UV-C. When leaves containing WFT eggs were exposed to UV-C doses known to cause 30–40% mortality in adults, 86–98% fewer eggs hatched compared to untreated controls. Ornamental plants exposed to UV-C doses lethal to eggs, second instars, and adult WFT either showed no damage, or when damage occurred, plants recovered within 14–30 days. Additional studies under controlled greenhouse conditions are needed to elucidate the effectiveness of UV-C radiance against WFT over time and its compatibility with biological control and other IPM practices. Full article

Scholars have documented positive and negative relationships between adolescents’ critical consciousness and mental health. This study aims to clarify the role of friendship networks contributing to these associations. Using egocentric network data from a nationwide adolescent sample (N = 984, 55.0% female, 23.9% nonbinary, 72.7% non-white), regression analyses examined whether adolescents’ psychological distress and flourishing were predicted by their friend group’s average critical consciousness and the difference between adolescents and their friends on critical consciousness dimensions (sociopolitical action, critical agency, and critical reflection), accounting for network and demographic covariates. Higher friend group critical consciousness positively predicted flourishing, and higher friend group sociopolitical action negatively predicted psychological distress. Adolescents who participated in sociopolitical action more frequently than their friends had higher psychological distress and lower flourishing. Those with higher agency than their friends had lower flourishing. At the individual level, adolescents’ sociopolitical action predicted higher psychological distress and flourishing, critical agency predicted higher flourishing, and critical reflection predicted higher psychological distress and lower flourishing. Adolescent mental health is uniquely related to their friends’ critical consciousness. Findings highlight the utility of social network analyses for understanding social mechanisms that underlie relationships between critical consciousness and mental health. Full article

Aspergillus fumigatus is commonly found in the airway and is associated with airway inflammatory diseases. Zinc oxide (ZO) is known to be an essential microelement that facilitates fungal survival, growth, and proliferation. This study aimed to investigate the impact of ZO on A. fumigatus-induced fungal sinusitis in rabbits. Twenty-eight New Zealand white rabbits were divided into four groups for this study. Group 1 (6 sides) was treated with intramaxillary phosphate buffer saline (PBS) served as the negative control, Group 2 (6 sides) received intramaxillary PBS and ZO, Group 3 (8 sides) was treated with intramaxillary A. fumigatus alone, and Group 4 (8 sides) treated with intramaxillary A. fumigatus with ZO. After 4 and 12 weeks, sinus mucosal cytokine and transcription factor expressions were determined. A histological analysis was performed to determine inflammatory cell infiltration, number of secretory cells, and mucosal thickness. Fungal biofilm formation was determined using confocal laser microscopy. The intramaxillary instillation of A. fumigatus conidia led to an increase in protein and mRNA expression of interleukin (IL)-1β and IL-8 in the maxillary sinus mucosa. They were associated with mitogen-activated protein kinase and activator protein-1. Furthermore, intramaxillary instillation of fungal conidia resulted in significant enhancement of inflammatory cell infiltration, epithelial thickening, and fungal biofilm formation. However, intramaxillary ZO did not have a significant impact on A. fumigatus-induced cytokine protein and mRNA expression, and inflammatory cell infiltration and epithelial thickness in sinonasal mucosa. While intramaxillary instillation of A. fumigatus increased mucosal inflammation, cytokine production, and biofilm formation, the intramaxillary application of ZO did not have a significant influence on inflammation in the maxillary sinus mucosa. Full article

Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii. One-third of the world’s population has come into contact with this parasite. In Mexico, the prevalence is between 15% and 50% in the general population and 34.9% in women with high-risk pregnancies. In pregnancy, the highest incidence of infection occurs in the third trimester and fetal damage is inversely proportional to gestational age. Maternal hormones play a fundamental role in the immune response. There are very few studies, with controversial results, on the levels of increased hormones and their relationship to the kinetics of T. gondii infections during pregnancy. The aim was to determine the serum levels of 17-β estradiol, prolactin, and progesterone, and their association with anti-T. gondii antibodies’ kinetics in pregnancy. Fifty-two pregnant patients were studied. A questionnaire with sociodemographic and clinical aspects was used. Afterward, 10 mL of venous blood was collected by venipuncture every trimester. The concentrations of 17-β estradiol, progesterone, and prolactin were measured, using the ELISA method. In addition, anti-Toxoplasma IgG and IgM antibodies were also determined in the first, second, and third trimester. The prevalence of anti-Toxoplasma IgG antibodies was 26.92% in the first and second trimester and 32.7% in the third trimester. In seropositive women, 17-β estradiol increased in the second and third trimesters of pregnancy. Progesterone increased significantly p < 0.039 in the third trimester in these women, while prolactin increased in the second trimester with a statistical significance of p < 0.021. In addition, 17-β estradiol, progesterone, and prolactin are associated with T. gondii infection during pregnancy. New studies are necessary to clarify the specific mechanisms of immune response related to these hormones during pregnancy. Full article

It is known that sialyllactose (SL) in mammalians is a major source of sialic acid (Sia), which can further form cytidine monophosphate sialic acid (CMP-Sia), and the final product is polysialic acid (polySia) using polysialyltransferases (polySTs) on the neural cell adhesion molecule (NCAM). This process is called NCAM polysialylation. The overexpression of polysialylation is strongly related to cancer cell migration, invasion, and metastasis. In order to inhibit the overexpression of polysialylation, in this study, SL was selected as an inhibitor to test whether polysialylation could be inhibited. Our results suggest that the interactions between the polysialyltransferase domain (PSTD) in polyST and CMP-Siaand the PSTD and polySia could be inhibited when the 3′-sialyllactose (3′-SL) or 6′-sialyllactose (6′-SL) concentration is about 0.5 mM or 6′-SL and 3 mM, respectively. The results also show that SLs (particularly for 3′-SL) are the ideal inhibitors compared with another two inhibitors, low-molecular-weight heparin (LMWH) and cytidine monophosphate (CMP), because 3’-SL can not only be used to inhibit NCAM polysialylation, but is also one of the best supplements for infant formula and the gut health system. Full article

It is crucial to increase the resilience of the global food production and distribution systems against the growing concerns relating to factors that could cause global catastrophic infrastructure losses, such as nuclear war or a worldwide pandemic. Currently, such an event would result in the global loss of industry, including the ability to drill and refine crude oil. In such an event, the existing above-ground reserves of diesel and gasoline are likely to still be intact but would only be able to power the production and transportation of food between 158 days and 481 days with 80% confidence, where the mean is 195 days at current rates. This paper investigates a novel group of interventions in relation to the scenario of providing food under these conditions. It was found that by using a plausible combination of wood gasification, increasing vehicle utilisation rate, and reducing food consumption, the stockpile duration could increase to between 382 days and 1501 days with 80% confidence, where the mean is 757 days. This is an improvement in mean duration by a factor of 3.9. It was discovered that diesel is the limiting fuel in all scenarios due to wood gas only being a partial replacement for diesel fuel and also because of the prevalence of diesel engines in both the agricultural and trucking industries. A sensitivity analysis was completed identifying that reducing food consumption to minimum levels was the most effective method to prolong diesel reserves. The other factors that benefited from extending fuel reserves in terms of their effectiveness are reducing the lag time before gasification devices are installed, increasing the rate at which gasification devices are installed, and increasing the agricultural equipment utilisation rate. Full article

In open and shared workplaces, like co-working spaces or educational studios, thermal preferences vary widely among occupants. With the rise of flexible organizational workplace strategies, the challenge lies in balancing optimum, efficient temperature setpoints with maintaining occupants’ comfort. A potential solution involves a deeper understanding of variations in indoor climate and building occupants’ decision-making and preferences. This paper explores how an Occupant-Centric Digital Twin (OCDT) might address this by mapping indoor microclimates through a grid of IoT temperature sensors in real time. A large-screen display is utilized to present and visualize these data in an open workplace. The goal is to enhance awareness and provide agency for occupants to identify zones that align with their individual thermal preferences. A mixed-method occupant study (N = 27) was conducted to validate the approach. Exposure to the OCDT display resulted in higher thermal satisfaction among participants (p-value = 1.269 × 10⁻⁵, 0.05 significance level). The novelty of OCDT lies in extending the use of digital twin technology from facility managers to occupants, by granting them the agency to address comfort issues even in buildings where they lack direct control over the thermostat. This approach paves the way for a future where occupants in open workspaces can make informed decisions about where to work and how to achieve thermal comfort in those choices. Full article

Acute kidney injury (AKI) is a highly prevalent and a critical complication of cardiac surgery (CS). Serum lactate (sLac) levels have consistently shown an association with morbimortality after CS. We performed a cross-sectional study including 264 adult patients that had a cardiac surgery between January and December 2020. Logistic regression analysis was performed to determine factors associated with AKI development. We measured the postoperative levels of sLac for all participants immediately after CS (T₀) and at 4 h (T₄) after the surgical intervention. A linear regression model was used to identify the factors influencing both sLac metrics. We identified four risk predictors of AKI; one was preoperative (atrial fibrillation), one intraoperative (cardiopulmonary bypass time), and two were postoperative (length of hospital stay and postoperative sLac). T₀ and T₄ sLac levels were higher among CS-AKI patients than in Non-CS-AKI patients. Postoperative sLac levels were significant independent predictors of CSA-AKI, and sLac levels are influenced by length of hospital stay, the number of transfused packed red blood cells, and the use of furosemide in CS-AKI patients. These findings may facilitate the earlier identification of patients susceptible to AKI after CS. Full article

Deep learning image reconstruction (DLIR) algorithms employ convolutional neural networks (CNNs) for CT image reconstruction to produce CT images with a very low noise level, even at a low radiation dose. The aim of this study was to assess whether the DLIR algorithm reduces the CT effective dose (ED) and improves CT image quality in comparison with filtered back projection (FBP) and iterative reconstruction (IR) algorithms in intensive care unit (ICU) patients. We identified all consecutive patients referred to the ICU of a single hospital who underwent at least two consecutive chest and/or abdominal contrast-enhanced CT scans within a time period of 30 days using DLIR and subsequently the FBP or IR algorithm (Advanced Modeled Iterative Reconstruction [ADMIRE] model-based algorithm or Adaptive Iterative Dose Reduction 3D [AIDR 3D] hybrid algorithm) for CT image reconstruction. The radiation ED, noise level, and signal-to-noise ratio (SNR) were compared between the different CT scanners. The non-parametric Wilcoxon test was used for statistical comparison. Statistical significance was set at p < 0.05. A total of 83 patients (mean age, 59 ± 15 years [standard deviation]; 56 men) were included. DLIR vs. FBP reduced the ED (18.45 ± 13.16 mSv vs. 22.06 ± 9.55 mSv, p < 0.05), while DLIR vs. FBP and vs. ADMIRE and AIDR 3D IR algorithms reduced image noise (8.45 ± 3.24 vs. 14.85 ± 2.73 vs. 14.77 ± 32.77 and 11.17 ± 32.77, p < 0.05) and increased the SNR (11.53 ± 9.28 vs. 3.99 ± 1.23 vs. 5.84 ± 2.74 and 3.58 ± 2.74, p < 0.05). CT scanners employing DLIR improved the SNR compared to CT scanners using FBP or IR algorithms in ICU patients despite maintaining a reduced ED. Full article

This epidemiological model forecasted reductions in recurrences and recurrence treatment cost savings with adjuvant atezolizumab vs best supportive care among Canadians with stage II-IIIA non-small cell lung cancer (NSCLC) at national and provincial levels. The population had resected, programmed cell death 1 ligand 1 (PD-L1)–high (≥50%), EGFR−, ALK−, stage II-IIIA NSCLC eligible for adjuvant treatment. Patients with recurrence or death and the costs of treating recurrences were estimated for those receiving adjuvant atezolizumab or best supportive care each year (2024–2034). Proportions of patients expected to be event free up to 10 years after treatment initiation were extrapolated with parametric survival analyses. In the base case analysis, 240 fewer recurrences were estimated to occur over 10 years (2024–2034) with adjuvant atezolizumab vs best supportive care across Canada, with 136 (57%) and 104 (43%) fewer locoregional and metastatic recurrences, respectively. Projected costs of treated recurrences were CAD 33.2 million less over 10 years with adjuvant atezolizumab at a national level (adjuvant atezolizumab, CAD 135.8 million; best supportive care, CAD 169.0 million). This model predicts a considerable long-term reduction in recurrences and substantial treatment cost savings with adjuvant atezolizumab vs best supportive care for patients with PD-L1–high early-stage NSCLC in Canada. Full article

The combined use of lasmiditan and triptan is unexplored in medical literature. This study aimed to investigate whether the intake of lasmiditan following triptan improves migraine pain. Following triptan intake, if headache relief was less than 50% at 1 h, patients took 50 mg of lasmiditan within 2 h of migraine onset. Patients recorded headache intensity and adverse events (AEs) caused by lasmiditan at 1, 2, and 4 h after the intake of an additional 50 mg of lasmiditan. A significant reduction in pain scale was observed post 50 mg lasmiditan intake (p < 0.001, t-test). Pain relief was reported for 32 migraine attacks (80%) at 1 h after additional lasmiditan intake. Although AEs were observed in 63% of the patients who took an additional lasmiditan, most were mild and resolved 1 h after lasmiditan intake. Our study revealed the significant headache relief provided by an additional lasmiditan for patients who did not achieve satisfactory results following initial triptan intake for treating migraine. The AEs associated with this treatment strategy were mild and lasted for a short time. This study suggested that the combination of triptan and lasmiditan is promising for the treatment of migraine and should be studied in a randomized placebo-controlled trial. Full article

Background: Investigations have shown the different impacts that ACEs have on an individual’s adult life, on both physical and mental health, but they have not yet shown the issue of the influence of ACEs on adults and young adults. Objective/Participants and Setting: This systematic review, performed according to the PRISMA norms and guidelines, intended to understand the most frequent outcomes of adverse childhood experiences in the life of young adults and adults. Methods: Studies were identified through multiple literature search databases at EBSCOhost, Web of Science, and PubMed April 2023, and a total of 279 studies, published between 1999 and 2002, were excluded, 256 because of multiple factors: being duplicates, showing statistical analysis with correlations only, being systematic reviews or case studies, comprising individuals under the age of 18, and not meeting the intended theme; ultimately, we selected for the review a total of 23 studies. Results and Conclusions: The impacts of the various articles are subdivided into three main themes: antisocial and criminal behaviour; sexual Behaviour and intimate partner violence; and attachment, quality of life, and therapeutic alliance. Full article

COVID-19, caused by the SARS-CoV-2 virus, is a highly pathogenic emerging infectious disease. Healthcare personnel (HCP) are presumably at higher risk of acquiring emerging infections because of occupational exposure. The prevalence of COVID-19 in HCP is unknown, particularly in low- to middle-income countries like El Salvador. The goal of this study was to determine the seroprevalence of anti-SARS-CoV-2 antibodies among HCP in El Salvador just prior to vaccine rollout in March 2021. We evaluated 2176 participants from a nationally representative sample of national healthcare institutions. We found 40.4% (n = 880) of the study participants were seropositive for anti-spike protein antibodies. Significant factors associated with infection included younger age; living within the central, more populated zone of the country; living in a larger household (≥7 members); household members with COVID-19 or compatible symptoms; and those who worked in auxiliary services (i.e., housekeeping and food services). These findings provide insight into opportunities to mitigate SARS-CoV-2 risk and other emerging respiratory pathogens in HCP in El Salvador. Full article