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Title:	Allosteric coupling from G protein to the agonist-binding pocket in GPCRs
Source:	Nature [0028-0836] DeVree, Brian yr:2016

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description	3.	Isogai, S. "Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor." Nature 530.7589 (2016): 237-241.
description	4.	Ring, Aaron M. "Adrenaline-activated structure of Î²2-adrenoceptor stabilized by an engineered nanobody." Nature 502.7472 (2013): 575-579.
description	5.	Pierce, Kristen L. "Signalling : Seven-transmembrane receptors." Nature Reviews. Molecular Cell Biology 3.9 (2002): 639-650.
description	6.	Weis, William I. "Structural insights into G-protein-coupled receptor activation." Current opinion in structural biology 18.6 (2008): 734-740.
description	7.	Lagerström, Malin C C. "Structural diversity of G protein-coupled receptors and significance for drug discovery." Nature reviews. Drug discovery 7.4 (2008): 339-57.
description	8.	Rosenbaum, M. "The structure and function of G-protein-coupled receptors." Nature 459.7245 (2009): 356-63.
description	9.	Pitcher, Julie A. "G PROTEIN–COUPLED RECEPTOR KINASES." Annual review of biochemistry 67.1 1 (1998): 653-692.
description	10.	Moukhametzianov, R. "Two distinct conformations of helix 6 observed in antagonist-bound structures of a {beta}1-adrenergic receptor." Proceedings of the National Academy of Sciences of the United States of America 108.20: 8228-8232.
description	11.	Rosenbaum, D. "Structure and function of an irreversible agonist-beta(2) adrenoceptor complex." Nature 469.7329 (2011): 236-242.
description	12.	Rasmussen, S. "Crystal structure of the human beta(2) adrenergic G-protein-coupled receptor." Nature 450.7168 (2007): 383-53.
description	13.	Shaywitz, A J J. "CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals." Annual review of biochemistry 68.1 (1999): 821-861.
description	14.	Hendrickson, Rebecca C. "Noradrenergic dysregulation in the pathophysiology of PTSD." Experimental neurology 284.Pt B (2016): 181-195.
description	15.	Piacentino, Cynthia L. "RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins." Development 143.4 (2016): 703-14.
description	16.	Opitz, C. "An economic approach to efficient isotope labeling in insect cells using homemade 15N-, 13C- and 2H-labeled yeast extracts." Journal of biomolecular NMR 62.3 (2015): 373-85.
description	17.	Bouvier, M. "Unraveling the structural basis of GPCR activation and inactivation." Nature structural & molecular biology 20.5 (2013): 539-541.
description	18.	Stevens, Raymond C. "The GPCR Network: a large-scale collaboration to determine human GPCR structure and function." Nature reviews. Drug discovery 12.1 (2012): 25-34.
description	19.	KONSTANTOPULOS, A. "Adrenaline and blood lipids." Nature 188 (1960): 1115-6.
description	20.	Akram, K. "Prospective and retrospective recording of severe hypoglycaemia, and assessment of hypoglycaemia awareness in insulin-treated Type 2 diabetes." Diabetic medicine 26.12 (2009): 1306-1308.