Abstract
Till and McCulloch1 have observed that cells obtained from mouse bone marrow can produce colonies of cells with haematopoietic competence when injected into the spleens of irradiated mice. Their findings verify the earlier reports of other workers, notably Jacobson et al.2 and Cole et al.3, who observed that the partial shielding of either bone marrow or spleen, or the injection of homogenates of these tissues from normal animals into irradiated animals, would prevent deaths normally associated with the haematopoietic syndrome.
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References
Till, J. E., and McCulloch, E. A., Radiat. Res., 14, 213 (1961).
Jacobson, L. O., Simmons, E. L., Bethard, W. F., Marks, E. K., and Robson, M. J., Proc. Soc. Exp. Biol. and Med., 13, 455 (1950).
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McCulloch, E. A., Rev. Franç. Etudes Clin. et Biol., 8, 15 (1963).
McCulloch, E. A., and Till, J. E., J. Cell. Comp. Physiol., 61, 301 (1963).
Proc. Dec. 1965 Conf. Bone Marrow Transplantation and Radiation Recovery.
Gurney, C. W., “The Regulation of Hemopoietic Stem Cell Compartment”, paper presented at Dec. 1965 Conf. Bone Marrow Transplantation and Radiation Recovery.
Hennessy, T. G., and Huff, R. L., Proc. Soc. Exp. Biol. and Med., 73, 436 (1950).
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Popp, R. A., Congdon, C. C., and Goodman, J. W., Experimental Hematology, 8, 21 (1965).
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OKUNEWICK, J., SPENCER, M., GLANCY, G. et al. Erythropoiesis in the Regenerating Spleen. Nature 213, 302–303 (1967). https://doi.org/10.1038/213302a0
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DOI: https://doi.org/10.1038/213302a0
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