Follow the leader

Latest research

1. 1. Developmental Biology
   2. Structural Biology and Molecular Biophysics

   Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling

   Samuel C Griffiths, Jia Tan ... Hsin-Yi Henry Ho
2. 1. Computational and Systems Biology
   2. Cancer Biology

   Comparison of Tug-of-War Models Assuming Moran versus Branching Process Population Dynamics

   Khanh N. Dinh, Monika K. Kurpas, Marek Kimmel
3. 1. Immunology and Inflammation

   Self-inhibiting percolation and viral spreading in epithelial tissue

   Xiaochan Xu, Bjarke Frost Nielsen, Kim Sneppen
4. 1. Developmental Biology
   2. Immunology and Inflammation

   Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

   Tobias Weinberger, Messerer Denise ... Christian Schulz

   In cardiac ischemia/reperfusion injury, resident macrophages orchestrate the immune response and positively influence postinfarct remodeling, whereas recruited macrophages determine infarct size.
5. 1. Cell Biology
   2. Developmental Biology

   Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

   Corey D Holman, Alexander P Sakers ... Patrick Seale

   Single-cell expression profiling and genetic lineage analysis show that aging impairs adipocyte differentiation from precursor cells and blocks the thermogenic activation of adipocytes during cold exposure.
6. 1. Neuroscience

   Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain

   Ya-Hui Lin, Li-Wen Wang ... Li-An Chu

   A new approach uses heat-induced antigen retrieval to enable tissue clearing, multiple-round immunostaining, and expansion microscopy for volumetric imaging of centimeter-scale clinical formalin-fixed paraffin-embedded specimens.
7. 1. Neuroscience

   Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles

   Yevgenia Rosenblum, Mahdad Jafarzadeh Esfahani ... Martin Dresler
8. 1. Microbiology and Infectious Disease
   2. Physics of Living Systems

   Potassium-mediated bacterial chemotactic response

   Chi Zhang, Rongjing Zhang, Junhua Yuan
9. 1. Developmental Biology

   Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells

   Adriana K. Alexander, Karina F. Rodriguez ... Humphrey Hung-Chang Yao
10. 1. Neuroscience

    Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons

    Ricardo Raudales, Gukhan Kim ... Z. Josh Huang