One of the measures set forth by the European Green Deal to decarbonize the freight transport sector is the promotion of inland waterway transport (IWT), and particularly intermodal transport in Europe. To facilitate intermodal transport on the Danube, we developed six new barge designs for the transport of 45′ pallet-wide high-cube containers using a four-step approach. Our approach consisted of detailed desk research, followed by the design and further analysis of the identified barge types, considering, for example, sightlines and stability. Their container carrying capacity reaches up to 90 containers in three layers, which is double the capacity of existing standard barges on the Danube. Nevertheless, three-layer transport is hardly feasible in several cases, due to restrictions regarding sightlines and stability. We conclude that each loading condition must be evaluated separately to determine the best barge design option for each case. This study is limited by its geographical scope and the type of container used to develop the new barge designs. A possible direction for further research could be using other container types and/or extending the geographical scope to extend the usability of our container barge designs. Full article

During the COVID-19 pandemic, the education and healthcare sectors were severely affected. There is a need to investigate the ways in which these workers in at-risk sectors can be protected and through what mechanisms. The aims of this research are, therefore, (1) to assess the mediating role of job demands and resources in the relationship between psychosocial safety climate (PSC) and work engagement and emotional exhaustion, and (2) to test for sector-specific differences among education and healthcare professionals during the COVID-19 pandemic. In the study, which employed a longitudinal design including three measurement times, 70 education professionals and 69 healthcare professionals completed a questionnaire measuring PSC, psychological demands, social support, recognition, work engagement, and emotional exhaustion. The results show that PSC was significantly higher among education professionals than among healthcare professionals. When considering both job sectors together, mediation analyses show that social support mediates the PSC–work engagement relationship, while psychological demands mediate the PSC–emotional exhaustion relationship. Moderated mediation analyses show that job sector is a moderator: among education professionals, colleague support and recognition mediate the PSC–work engagement relationship, and psychological demands mediate the PSC–emotional exhaustion relationship. PSC is associated with more balanced job demands and resources, higher work engagement, and lower emotional exhaustion among education and healthcare professionals. The study of these two sectors, which are both vital to society but also more exposed to adverse work conditions, shows the importance that managers and executives must attach to their mental health by improving their respective working conditions. Full article

Podophyllotoxin (PPT) is an active pharmaceutical ingredient (API) with established antitumor potential. However, due to its systemic toxicity, its use is restricted to topical treatment of anogenital warts. Less toxic PPT derivatives (e.g., etoposide and teniposide) are used intravenously as anticancer agents. PPT has been exploited as a scaffold of new potential therapeutic agents; however, fewer studies have been conducted on the parent molecule than on its derivatives. We have undertaken a study of ultrastructural changes induced by PPT on HaCaT keratinocytes. We have also tracked the intracellular localization of PPT using its fluorescent derivative (PPT-FL). Moreover, we performed molecular docking of both PPT and PPT-FL to compare their affinity to various binding sites of tubulin. Using the Presto blue viability assay, we established working concentrations of PPT in HaCaT cells. Subsequently, we have used selected concentrations to determine PPT effects at the ultrastructural level. Dynamics of PPT distribution by confocal microscopy was performed using PPT-FL. Molecular docking calculations were conducted using Glide. PPT induces a time-dependent cytotoxic effect on HaCaT cells. Within 24 h, we observed the elongation of cytoplasmic processes, formation of cytoplasmic vacuoles, progressive ER stress, and shortening of the mitochondrial long axis. After 48 h, we noticed disintegration of the cell membrane, progressive vacuolization, apoptotic/necrotic vesicles, and a change in the cell nucleus’s appearance. PPT-FL was detected within HaCaT cells after ~10 min of incubation and remained within cells in the following measurements. Molecular docking confirmed the formation of a stable complex between tubulin and both PPT and PPT-FL. However, it was formed at different binding sites. PPT is highly toxic to normal human keratinocytes, even at low concentrations. It promptly enters the cells, probably via endocytosis. At lower concentrations, PPT causes disruptions in both ER and mitochondria, while at higher concentrations, it leads to massive vacuolization with subsequent cell death. The novel derivative of PPT, PPT-FL, forms a stable complex with tubulin, and therefore, it is a useful tracker of intracellular PPT binding and trafficking. Full article

Type 2 diabetes mellitus (T2DM) is a risk factor for male infertility, but the underlying molecular mechanisms remain unclear. Advanced glycation end products (AGEs) are pathogenic molecules for diabetic vascular complications. Here, we investigated the effects of the DNA aptamer raised against AGEs (AGE-Apt) on testicular and sperm abnormalities in a T2DM mouse model. KK-Ay (DM) and wild-type (non-DM) 4- and 7-week-old male mice were sacrificed to collect the testes and spermatozoa for immunofluorescence, RT-PCR, and histological analyses. DM and non-DM 7-week-old mice were subcutaneously infused with the AGE-Apt or control-aptamer for 6 weeks and were then sacrificed. Plasma glucose, testicular AGEs, and Rage gene expression in 4-week-old DM mice and plasma glucose, testicular AGEs, oxidative stress, and pro-inflammatory gene expressions in 7-week-old DM mice were higher than those in age-matched non-DM mice, the latter of which was associated with seminiferous tubular dilation. AGE-Apt did not affect glycemic parameters, but it inhibited seminiferous tubular dilation, reduced the number of testicular macrophages and apoptotic cells, and restored the decrease in sperm concentration, motility, and viability of 13-week-old DM mice. Our findings suggest that AGEs-Apt may improve sperm abnormality by suppressing AGE–RAGE-induced oxidative stress and inflammation in the testes of DM mice. Full article

Background: The role of Enterobius vermicularis infestation in the context of appendicitis is largely overlooked, but Enterobius vermicularis is considered an unexpected and significant appendicectomy finding. The aim of this study was to investigate the frequency of Enterobius vermicularis findings in appendectomies and to evaluate the clinical and histopathologic features of patients with Enterobius vermicularis-associated acute appendicitis and those with appendiceal Enterobius vermicularis infestation. Methods: The medical records of all children who underwent an appendectomy in two large pediatric centers in Croatia between 1 January 2009 and 1 January 2024 were retrospectively reviewed. Of 6359 appendectomies, 61 (0.96%) children were diagnosed with Enterobius vermicularis on histopathology and included in further analysis. The groups were compared with regard to demographic characteristics, laboratory values, clinical features and histopathological findings. Results: The incidence of enterobiasis fluctuated slightly in the individual study years, but was constant overall. The median age of all patients was 11 years (IQR 8.5, 13), with females predominating (60.7%). Acute appendicitis was observed in 34% of the appendiceal species. The patients with Enterobius vermicularis infestation, without appendicitis, were younger (9 years (IQR 8, 13) vs. 12 years (IQR 10, 15); p = 0.020), had longer duration of symptoms (36 h (IQR, 12, 48) vs. 24 h (IQR, 12, 36); p = 0.034), lower body temperature (37 °C (IQR 36.8, 37.4) vs. 37.6 °C (IQR, 37, 38.6) p = 0.012), lower Appendicitis Inflammation Response (AIR) score (3 (IQR 2, 5) vs. 7 (IQR 5, 9.5) p < 0.001), lower incidence of rebound tenderness (57.1% vs. 20%; p = 0.003) and less frequent vomiting (12.5% vs. 47.6%; p = 0.004) compared to the patients with Enterobius vermicularis-associated acute appendicitis. Acute inflammatory markers in the laboratory showed significantly higher values in the group of patients with acute appendicitis: C-reactive protein (p = 0.009), White blood cells (p = 0.001) and neutrophils (p < 0.001). Eosinophilia was not found in any of the groups, although eosinophil counts were significantly higher in children who had Enterobius vermicularis infestation than in those with Enterobius vermicularis-related appendicitis (2.5% (IQR 0.9, 4.3) vs. 1.8% (IQR 0.7, 2.1); p = 0.040). Conclusions: Pediatric surgeons should consider Enterobius vermicularis infestation as a differential diagnosis when removing a vermiform appendix. Younger age, longer duration of symptoms, lower body temperature, lower AIR score, lower diameter of the appendix and normal laboratory inflammatory markers could predict Enterobius vermicularis infection in children presenting with right iliac fossa pain and avoid unnecessary appendectomy. Full article

The aim of this systematic review was to assess the effects of plyometric-jump training (PJT) on the physical fitness of youth with cerebral palsy (CP) compared with controls (i.e., standard therapy). The PRISMA 2020 guidelines were followed. Eligibility was assessed using the PICOS approach. Literature searches were conducted using the PubMed, Web of Science, and SCOPUS databases. Methodological study quality was assessed using the PEDro scale. Data were meta-analyzed by applying a random-effects model to calculate Hedges’ g effect sizes (ES), along with 95% confidence intervals (95% CI). The impact of heterogeneity was assessed (I² statistic), and the certainty of evidence was determined using the GRADE approach. Eight randomized-controlled studies with low-to-moderate methodological quality were included, involving male (n = 225) and female (n = 138) youth aged 9.5 to 14.6 years. PJT interventions lasted between 8 and 12 weeks with 2–4 weekly sessions. Compared with controls, PJT improved the muscle strength (ES = 0.66 [moderate], 95% CI = 0.36–0.96, p < 0.001, I² = 5.4%), static (ES = 0.69 [moderate], 95% CI= 0.33–1.04, p < 0.001, I² = 0.0%) and dynamic balance (ES = 0.85 [moderate], 95% CI = 0.12–1.58, p = 0.023, I² = 81.6%) of youth with CP. Therefore, PJT improves muscle strength and static and dynamic balance in youth with CP compared with controls. However, more high-quality randomized-controlled trials with larger sample sizes are needed to provide a more definitive recommendation regarding the use and safety of PJT to improve measures of physical fitness. Full article

Flooding, exacerbated by climate change, poses a significant threat to certain areas, increasing in frequency and severity. In response, the construction of supplementary dams has emerged as a reliable solution for flood management. This study employs a geospatial approach to assess the feasibility of constructing a supplementary dam near Linville, Brisbane, Australia, with the aim of mitigating floods and preventing overtopping failure at Wivenhoe Dam. Using QGIS software and a 25 m resolution DEM from the Queensland Spatial Catalogue ‘QSpatial’ website, four potential dam sites were analysed, considering cross-sections, watershed characteristics, and water volume calculations. Systematic selection criteria were applied on several dam wall options to identify the cost-effective and optimal one based on the dam wall dimensions, volume-to-area, and volume-to-cost ratios. The selected option was further assessed against predefined criteria yielding the optimal choice. The study provides insights into the feasibility and effectiveness of supplementary dam construction for flood mitigation in the region, with recommendations for future research and implementation plans for the asset owners. Full article

The HIV-1 nucleocapsid protein (NC) is a multifunctional viral protein necessary for HIV-1 replication. Recent studies have demonstrated that reverse transcription (RT) completes in the intact viral capsid, and the timing of RT and uncoating are correlated. How the small viral core stably contains the ~10 kbp double stranded (ds) DNA product of RT, and the role of NC in this process, are not well understood. We showed previously that NC binds and saturates dsDNA in a non-specific electrostatic binding mode that triggers uniform DNA self-attraction, condensing dsDNA into a tight globule against extending forces up to 10 pN. In this study, we use optical tweezers and atomic force microscopy to characterize the role of NC’s basic residues in dsDNA condensation. Basic residue mutations of NC lead to defective interaction with the dsDNA substrate, with the constant force plateau condensation observed with wild-type (WT) NC missing or diminished. These results suggest that NC’s high positive charge is essential to its dsDNA condensing activity, and electrostatic interactions involving NC’s basic residues are responsible in large part for the conformation, size, and stability of the dsDNA-protein complex inside the viral core. We observe DNA re-solubilization and charge reversal in the presence of excess NC, consistent with the electrostatic nature of NC-induced DNA condensation. Previous studies of HIV-1 replication in the presence of the same cationic residue mutations in NC showed significant defects in both single- and multiple-round viral infectivity. Although NC participates in many stages of viral replication, our results are consistent with the hypothesis that cationic residue mutations inhibit genomic DNA condensation, resulting in increased premature capsid uncoating and contributing to viral replication defects. Full article

The periosteum plays a critical role in bone repair and is significantly influenced by the surrounding immune microenvironment. In this study, we employed 10× single-cell RNA sequencing to create a detailed cellular atlas of the swine cranial periosteum, highlighting the cellular dynamics and interactions essential for cranial bone injury repair. We noted that such injuries lead to an increase in M2 macrophages, which are key in modulating the periosteum’s immune response and driving the bone regeneration process. These macrophages actively recruit periosteal stromal cells (PSCs) by secreting Neuregulin 1 (NRG1), a crucial factor in initiating bone regeneration. This recruitment process emphasizes the critical role of PSCs in effective bone repair, positioning them as primary targets for therapeutic interventions. Our results indicate that enhancing the interaction between M2 macrophages and PSCs could significantly improve the outcomes of treatments aimed at cranial bone repair and regeneration. Full article

The importance of natural plant materials in modern medicine is considerable, and raw materials with antiviral, antibacterial, antifungal, and anticancer properties are still sought because of microbe resistance and difficulties in anticancer therapy. This review focuses on the lemongrass Cymbopogon citratus (DC.) Stapf. and on the lemongrass oil properties and applications. Multiple applications of this plant were described in different latitudes and cultures, including cases of digestive disorders and anti-inflammatory, antipyretic, diaphoretic, stimulating, and antispasmodic conditions. Data from the literature on the composition of essential oil and extracts from C. citratus were analyzed, and the results of research on the antifungal, antibacterial, and antiviral effects were quoted. Essential oil inhibits the growth of fungi (Aspergillus niger, A. fumigatus, Candida spp.) and has an antibacterial effect (Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa). It also shows antiviral activity and deters insects. Lemongrass contains active substances with potential anticancer effects. This plant has apoptosis-stimulating properties, mainly through the activity of apigenin, which is the main active flavonoid in this plant. This active substance helps inhibit cell proliferation by stopping the cell cycle and directing cancer cells toward apoptosis. Full article

As firms increasingly engage in both corporate social responsibility (CSR) and irresponsibility (CSIR) activities, this study expands the traditional question “does it pay to do more CSR?” to explore the less-studied question “does it pay to do less CSIR?”. We employ stakeholder theory and expectancy disconfirmation theory to outline three sustainable strategies for firms to financially benefit (enlightened self-interest) from CSR/CSIR activities: proactive strategy (increasing CSR, or doing more good), rectification strategy (reducing CSIR, or doing less bad), and aggressive strategy (increasing CSR while reducing CSIR, or doing more good and less bad). Our research objective is to evaluate the financial viability of different CSR/CSIR strategies. We hypothesize that the rectification strategy will surpass the proactive approach, while anticipating that the aggressive strategy will emerge as the most financially advantageous. Our dataset consists of 12,567 firm-year observations (3422 firms) spanning 1994 to 2013, and we conduct rigorous analyses to evaluate these strategies. The findings reveal that the rectification strategy surpasses the proactive strategy, with the aggressive strategy emerging as the most advantageous. The study contributes theoretically and offers managerial insights into these results. Full article

Online medical teams (OMTs), a new mode of online healthcare service, have emerged in online health communities (OHCs) in China. This study attempts to explore the underlying mechanism of how OMTs’ engagement influences patient satisfaction through the lens of semantic features. This study also scrutinizes the moderating effect of multiple specializations on the link between OMTs’ engagement and semantic features. We utilized a linear model that had fixed effects controlled at the team level for analysis. A bootstrapping approach using 5000 samples was employed to test the mediation effects. The findings reveal that OMTs’ engagement significantly improves language concreteness in online team consultations, which subsequently enhances patient satisfaction. OMT engagement has a negative impact on emotional intensity, ultimately decreasing patient satisfaction. Multiple specializations strengthen the impact of OMT engagement on both language concreteness and emotional intensity. This study contributes to the literature on OMTs and patient satisfaction, providing insights into patients’ perceptions of OMTs’ engagement during online team consultation. This study also generates several implications for the practice of OHCs and OMTs. Full article

Histones are keys to many epigenetic events and their complexes have therapeutic and diagnostic importance. The determination of the structures of histone complexes is fundamental in the design of new drugs. Computational molecular docking is widely used for the prediction of target–ligand complexes. Large, linear peptides like the tail regions of histones are challenging ligands for docking due to their large conformational flexibility, extensive hydration, and weak interactions with the shallow binding pockets of their reader proteins. Thus, fast docking methods often fail to produce complex structures of such peptide ligands at a level appropriate for drug design. To address this challenge, and improve the structural quality of the docked complexes, post-docking refinement has been applied using various molecular dynamics (MD) approaches. However, a final consensus has not been reached on the desired MD refinement protocol. In this present study, MD refinement strategies were systematically explored on a set of problematic complexes of histone peptide ligands with relatively large errors in their docked geometries. Six protocols were compared that differ in their MD simulation parameters. In all cases, pre-MD hydration of the complex interface regions was applied to avoid the unwanted presence of empty cavities. The best-performing protocol achieved a median of 32% improvement over the docked structures in terms of the change in root mean squared deviations from the experimental references. The influence of structural factors and explicit hydration on the performance of post-docking MD refinements are also discussed to help with their implementation in future methods and applications. Full article

Sheep and goat may become carriers of some zoonotic diseases. They are important livestock and experimental model animals for human beings. The fast and accurate identification of genetic materials originating from sheep and goat can prevent and inhibit the spread of some zoonotic diseases, monitor market product quality, and maintain the stability of animal husbandry and food industries. This study proposed a methodology for identifying sheep and goat common specific sites from a genome-wide perspective. A total of 150 specific sites were selected from three data sources, including the coding sequences of single copy genes from nine species (sheep, goat, cow, pig, dog, horse, human, mouse, and chicken), the dbSNPs for these species, and human 100-way alignment data. These 150 sites exhibited low intraspecific heterogeneity in the resequencing data of 1450 samples from five species (sheep, goat, cow, pig, and chicken) and high interspecific divergence in the human 100-way alignment data after quality control. The results were proven to be reliable at the data level. Using the process proposed in this study, specific sites of other species can be screened, and genome-level species identification can be performed using the screened sites. Full article

A rare consensus points to the question of normativity, with an inclination towards the Eurocentric Frankfurt School of Critical Theory, which seems to have been central to Critical Terrorism Studies (CTS). Given the universality of knowledge exerting pressure on scholars to conform with traditional theoretical perspectives, terrorism studies pose inequality from Eurocentricity emerging in “the battle for hearts and minds” research. Some of these studies fall to the allure of connivance with the progressively “authoritarian demands of Western, liberal state and media practice”. Consequently, terrorism research risks being dominated by ethical and logical blindness within established research formations. In Africa, for example, some CTS scholars are subdued to cynically use their Africanity to authenticate the neo-colonial and neo-liberal agenda in terrorism research. This article explores the reimaging of subjugated knowledge through decolonisation of methods in CTS. Rooting for cognitive justice and adequate space for alternative knowledge to imperial science, the article contests the battle for Africa’s hearts and minds as a failed process that needs transformation. Consequently, this work is a contribution to epistemological debate between the global North and South, and the subsequent theoretical contestations in CTS. We argue for hybridity by re-constructing alternative frameworks of knowledge production. Full article

The International Maritime Organization (IMO) is currently rolling out more restrictive regulations in order to achieve net-zero GHG emissions by 2050. In response, the shipping industry is planning to pivot to green energy sources such as hydrogen fuel. However, since hydrogen has an extremely low boiling point (−253 °C), materials for storing liquid hydrogen must be highly resistant to low-temperature brittleness and hydrogen embrittlement. A 316L stainless steel is a typical material that meets these requirements, and various welds have been studied. In this study, 3 pass butt welding was performed by applying the FCAW (flux cored arc welding) process to 10 mm thick ASTM-A240M-316L stainless steel, with the size of the fusion zone and HAZ investigated by mechanical testing and heat transfer FE analysis according to process variables, such as heat input, welding speed, and the number of passes. In all cases, the yield and tensile strengths were about 10% and 3% higher than the base metal, respectively. Furthermore, heat transfer FE analysis showed an average error rate of 1.3% for penetration and 10.5% for width and confirmed the size of the HAZ, which experienced temperatures between 500 °C and 800 °C. Full article

In this study, we prepared the SnO₂/ZnFe₂O₄ (SZ) composite magnetic photocatalyst via a two-step hydrothermal method. Structural and performance analyses revealed that SZ-5 with a ZnFe₂O₄ mass ratio of 5% (SZ-5) exhibited optimal photocatalytic activity, achieving a 72.6% degradation rate of Rhodamine B (RhB) solution within 120 min. SZ-5 consisted of irregular nano blocks of SnO₂ combined with spherical nanoparticles of ZnFe₂O₄, with a saturated magnetization intensity of 1.27 emu/g. Moreover, the specific surface area of SnO₂ loaded with ZnFe₂O₄ increased, resulting in a decreased forbidden bandwidth and expanded light absorption range. The construction of a Z-type heterojunction structure between SnO₂ and ZnFe₂O₄ facilitated the migration of photogenerated charges, reduced the recombination rate of electron-hole pairs, and enhanced electrical conductivity. During the photocatalytic reaction, RhB was degraded by·OH, O₂⁻, and h⁺, in which O₂⁻ played a major role. Full article

Background: Resection margins are an important prognostic factor for patients with head and neck cancer. In general, for head and neck surgery, a margin > 5 mm is advised by the Royal College of Pathologists. However, this cannot always be achieved during laryngeal and hypopharyngeal surgery. The aim of this study is to identify the resection surfaces and measure the maximum feasible margins per subsite. The clinical relevance of these maximum feasible resection margins were analyzed in this descriptive anatomical study. Methods: head and neck surgeons and a pathologist from the Erasmus MC performed a total laryngectomy and laryngopharyngectomy on a head and neck specimen specifically available for research. Results: For a total laryngectomy, resection margins > 5 mm were not feasible for the ventral and dorsal resection surface. For a total laryngopharyngectomy, resection margins > 5 mm were not feasible for the ventral, dorsal and lateral resection surface. Conclusion: Clear resection margins, defined as a margin > 5 mm, are not always feasible in laryngeal and hypopharyngeal surgery, due to the anatomy of the larynx and tumor location. However, striving for a maximum feasible margin is still the main goal. We propose a new guideline for maximum feasible but adequate resection margins in larynx and hypopharynx tumor surgery. Full article

The influence of elevated temperatures and strain rate on the mechanical and structural properties of steel 42CrMo4 were analysed experimentally in this paper. The experiments were based on uniaxial tension and compression tests at high temperatures between 700 °C and 1100 °C and strain rates in the range 0.0018–0.1 s⁻¹. The influence of temperature and strain rate on yield stress, strain to fracture, hardness, structural changes, and fracture characteristics were analysed. The non-uniformity of deformations obtained at different values of the strain rate and temperature were also analysed. Analysis by scanning electron microscopy showed the ductile behaviour of the material. The degree of damage in the material caused by the presence of cavities increased with increasing deformation temperature. For all the presented deformation conditions, the formation of the fracture through the ductile fracture mechanism resulted from localized necking and the coalescence of microvoids. By increasing the deformation temperature and reducing the strain rate, the fracture behaviour of 42CrMo4 steel can be improved. Full article

The genus Brassica is an important source of food in the Mediterranean diet with documented nutritional and medicinal properties. However, few studies have investigated the phytochemical composition and the biological activity of wild Sicilian taxa. Thus, we aimed to study the chemical profile and the antioxidant potential, in vitro and in LPS-stimulated RAW 264.7 cells, of a methanolic extract of leaves of wild Brassica macrocarpa Guss (B. macrocarpa) (Egadi Islands; Sicily-Italy). B. macrocarpa methanolic extract showed a large amount of glucosinolates and different phenolic compounds. It exhibited antioxidant activity in the DPPH assay and in LPS-stimulated RAW 264.7 cells, being able to reduce NO and ROS levels and NOS2 mRNA expression. Our study demonstrated that Sicilian B. macrocarpa methanolic extract, in LPS-stimulated macrophages, efficiently counteracts oxidative stress and displays radical scavenging activity. Future studies are required to identify the contribution of the single phytocomponents, to characterize the action mechanism, and to reveal possible applications in human health. Full article

Unsupervised domain adaptation (UDA) aims to reapply the classifier to be ever-trained on a labeled source domain to a related unlabeled target domain. Recent progress in this line has evolved with the advance of network architectures from convolutional neural networks (CNNs) to transformers or both hybrids. However, this advance has to pay the cost of high computational overheads or complex training processes. In this paper, we propose an efficient alternative hybrid architecture by marrying transformer to contextual convolution (TransConv) to solve UDA tasks. Different from previous transformer based UDA architectures, TransConv has two special aspects: (1) reviving the multilayer perception (MLP) of transformer encoders with Gaussian channel attention fusion for robustness, and (2) mixing contextual features to highly efficient dynamic convolutions for cross-domain interaction. As a result, TransConv enables to calibrate interdomain feature semantics from the global features and the local ones. Experimental results on five benchmarks show that TransConv attains remarkable results with high efficiency as compared to the existing UDA methods. Full article

Currently, there are many enterprises involved in extracting and processing of primary raw materials. The danger of working in this industry consists in the formation of cracks in rocks of the pit side slopes, which can lead to destruction. This article discusses the existing systems for monitoring the pit collapse prevention. The most promising is the use of systems with fiber-optic sensors. However, use of these systems is associated with some difficulties due to high costs, low noise immunity, and in some cases, the requirement for additional equipment to improve the reliability of measurements. A completely new method of processing the data from a fiber-optic sensor that simplifies the design and reduces the cost of the device is proposed considering the experience of previous developments. The system uses artificial intelligence, which improves the data processing. The theoretical part is dedicated to the development of foundations, and the analysis of the nonlinear properties of the physical and mathematical model of optical processes associated with the propagation of an electromagnetic wave in a fiber-optic material was developed. The results of experimental and theoretical applied research, which are important for the development of fiber-optic systems for monitoring the pit collapse prevention, are presented. The dependences of optical losses and the number of pixels on the dis-placement were obtained. The accuracy of the method corresponds to the accuracy of the device by which it is calibrated and is 0.001 mm. The developed hardware-software complex is able to track the rate of changing the derivative of the light wave intensity in time, as well as changing the shape of the spot and transition of pixels from white to black. Full article