References
Anderson TW, Reid DBW (1974) A double-blind trial of vitamin E in angina pectoris. Am J Clin Nutr 27:1174–1178
Bierenbaum ML, et al. (1985) The effect of supplemental vitamin E on serum parameters in diabetics, postcoronary and normal subjects. Nutr Res Int 31:1171–1180
Bursell SE, et al. (1999) High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes. Diabetes Care 22:1245–1251
FSA (Food Standards Agency) (2003) Expert Group on Vitamins and Minerals. Risk assessment of vitamin E, pp 145–154
Gillilan RE, et al. (1977) Quantitative evaluation of vitamin E in the treatment of angina pectoris. Am Heart J 93:444–449
Heart Protection Study Collaborative Group (2002) MRC/BHF Heart protection study of antioxidant vitamin supplementation in 20.536 high-risk individuals: a randomised placebo-controlled trial. Lancet 360:23–32
Kim JM, White RH (1996) Effect of vitamin E on the anticoagulant response to warfarin. Am J Cardiol 77:545–546
Leppälä JM, et al. (2000a) Controlled trial of a-tocopherol and b-carotene supplements on stroke incidence and mortality in male smokers. Arterioscler Thromb Vasc Biol 20:230–235
Leppäla JM, et al. (2000b) Vitamin E and beta carotene supplementation in high risk for stroke. A subgroup analysis of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Arch Neurol 57:1503–1509
Meydani SN, et al. (1998) Assessment of the safety of supplementation with different amounts of vitamin E in healthy older adults. Am J Clin Nutr 68:311–318
Primary Prevention Project (2001) Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Lancet 357:89–95
Sano M,et al. (1997) A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer’s disease. The Alzheimer’s Disease Cooperative Study. N Engl J Med 336:1216–1222
SCF (Scientific Committee on Food) (2003) Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Vitamin E
Stephens NG, et al. (1996) Randomized controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 347:781–786
Yusef S, et al. (2000) Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes prevention Evaluation Study Investigators. N Engl J Med 342:154–160
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Azzi, A., Brigelius-Flohé, R., Kelly, F. et al. On the opinion of the European Commission “Scientific Committee on Food” regarding the tolerable upper intake level of vitamin E (2003). Eur J Nutr 44, 60–62 (2005). https://doi.org/10.1007/s00394-005-0549-8
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00394-005-0549-8