Insects readily evolve resistance to insecticidal proteins that are introduced into genetically modified crop plants. Continuous directed evolution has now been used to engineer a toxin that overcomes insect resistance. See Article p.58
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Notes
References
Betz, F. S., Hammond, B. G. & Fuchs, R. L. Regul. Toxicol. Pharmacol. 32, 156–173 (2000).
Tabashnik, B. E., Brévault, T. & Carrière, Y. Nature Biotechnol. 31, 510–521 (2013).
Badran, A. H. et al. Nature 533, 58–63 (2016).
Pardo-López, L., Soberón, M. & Bravo, A. FEMS Microbiol. Rev. 37, 3–22 (2013).
Lu, Y., Wu, K., Jiang, Y., Guo, Y. & Desneux, N. Nature 487, 362–365 (2012).
Carpenter, J. E. Nature Biotechnol. 28, 319–321 (2010).
Esvelt, K. M., Carlson, J. C. & Liu, D. R. Nature 472, 499–503 (2011).
http://www.un.org/en/development/desa/news/population/2015-report.html
Godfray, H. C. J. et al. Science 327, 812–818 (2010).
Carrière, Y., Fabrick, J. A. & Tabashnik, B. E. Trends Biotechnol. 34, 291–302 (2016).
Author information
Authors and Affiliations
Corresponding author
Related links
Rights and permissions
About this article
Cite this article
Dovrat, D., Aharoni, A. Evolved to overcome Bt-toxin resistance. Nature 533, 39–40 (2016). https://doi.org/10.1038/nature17893
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature17893