The 2023 MDPI Annual Report has
been released!
 
18 pages, 21225 KiB  
Article
Thought to Be Extinct, but Still Alive Today: The Miocene Genus Primascena Klimaszewsi, 1997 (Hemiptera: Psyllidae) in the Light of Two Extant Species from Brazil
by Daniel Burckhardt and Dalva L. Queiroz
Insects 2024, 15(6), 382; https://doi.org/10.3390/insects15060382 (registering DOI) - 23 May 2024
Abstract
Fossils can document the morphological diversification through time and date lineages, providing relevant characters are preserved. Primascena Klimaszewsi, 1997 was erected for P. subita Klimaszewsi, 1997 on the basis of a single, partly damaged male from Dominican amber. Originally assigned to Rhinocolidae: Paurocephalinae, [...] Read more.
Fossils can document the morphological diversification through time and date lineages, providing relevant characters are preserved. Primascena Klimaszewsi, 1997 was erected for P. subita Klimaszewsi, 1997 on the basis of a single, partly damaged male from Dominican amber. Originally assigned to Rhinocolidae: Paurocephalinae, the genus was subsequently transferred to Psyllidae: Aphalaroidinae. Recently, two undescribed species resembling the fossil species were discovered in Brazil (Mato Grosso do Sul), allowing a detailed morphological study of adults and immatures. Based on the morphological study, a revised diagnosis of the genus is provided, including the previously unknown female and fifth instar immatures. Primascena subita is redescribed and P. empsycha n. spec. and P. ruprechtiae n. spec. are formally described and illustrated. An identification key is provided for the species of Primascena. A cladistic morphological analysis supports the placement of the two new species in Primascena, and of this genus in the Aphalaroidinae. It is sister to all but Aphalaroida, though with little support. The two Brazilian species develop on Ruprechtia spp. (Polygonaceae: Eriogonoideae), an unusual psyllid host. Immatures of P. ruprechtiae are free-living on the lower leaf face and do not induce galls. Full article
(This article belongs to the Special Issue Phylogeny and Morphological Evolution of Hemiptera)
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19 pages, 10014 KiB  
Article
Landscape Pattern Changes of Aquatic Vegetation Communities and Their Response to Hydrological Processes in Poyang Lake, China
by Zhengtao Zhu, Huilin Wang, Zhonghua Yang, Wenxin Huai, Dong Huang and Xiaohong Chen
Water 2024, 16(11), 1482; https://doi.org/10.3390/w16111482 (registering DOI) - 23 May 2024
Abstract
Hydrology is an important environmental factor for the evolution of wetland landscape patterns. In the past 20 years, Poyang Lake, the largest freshwater lake in China, has experienced significant inundation shrinkage and water level decrease, posing a significant threat to the local vegetation [...] Read more.
Hydrology is an important environmental factor for the evolution of wetland landscape patterns. In the past 20 years, Poyang Lake, the largest freshwater lake in China, has experienced significant inundation shrinkage and water level decrease, posing a significant threat to the local vegetation community. To explore the potential relationship between aquatic vegetation and hydrological processes in the recent hydrological situation, in this study, the landscape patterns of aquatic vegetation communities in Poyang Lake were studied using time-series Landsat remote sensing images and a support vector machine classifier. The stepwise regression analysis method was adopted to analyze the relationship between the vegetation area and hydrological factors. The results indicated that the area of submerged and emergent vegetation in the entire lake decreased significantly from 2001 to 2017, whereas the area of moist vegetation showed a remarkably increasing trend. The average distribution elevation of the submerged vegetation increased by 0.06 m per year. The corresponding landscape patterns showed that the degree of fragmentation of aquatic vegetation communities in Poyang Lake increased. Several hydrological factors were selected to quantify the potential impact of water level fluctuations. The correlation analysis results indicated that hydrological conditions during the rising- and high-water periods may be the key factors affecting the area of aquatic vegetation. This study systematically investigated the evolution of vegetation communities in Poyang Lake wetlands over the past two decades, which contributes to the protection and management of this unique ecosystem. Full article
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20 pages, 1014 KiB  
Article
Analyzing Potential Failures and Effects in a Pilot-Scale Biomass Preprocessing Facility for Improved Reliability
by Rachel M. Emerson, Nepu Saha, Pralhad H. Burli, Jordan L. Klinger, Tiasha Bhattacharjee and Lorenzo Vega-Montoto
Energies 2024, 17(11), 2516; https://doi.org/10.3390/en17112516 (registering DOI) - 23 May 2024
Abstract
This study demonstrates a failure identification methodology applied to a preprocessing facility generating conversion-ready feedstocks from biomass meeting conversion process critical quality attribute (CQA) specifications. Failure Modes and Effects Analysis (FMEA) was used as an industrially relevant risk analysis approach to evaluate a [...] Read more.
This study demonstrates a failure identification methodology applied to a preprocessing facility generating conversion-ready feedstocks from biomass meeting conversion process critical quality attribute (CQA) specifications. Failure Modes and Effects Analysis (FMEA) was used as an industrially relevant risk analysis approach to evaluate a logging residue preprocessing system to prepare feedstock for pyrolysis conversion. Risk evaluations considered both system-level and operation unit-level assessments considering process efficiency, product quality, cost, sustainability, and safety. Key outputs included estimations of semi-quantitative risk scores for each failure, identification of the failure impacts, identification of failure causes associated with material attributes and process parameters, ranking success rates of failure detection methods, and speculation of potential mitigation strategies for decreasing failure risk scores. Results showed that deviations from moisture specifications had cascading consequences for other CQAs along with process safety implications. Failures linked to fixed carbon specifications carried the highest risk scores for product quality and process efficiency impacts. As increased throughput can be inversely related to meeting product quality specifications; achieving throughput and other material-based CQAs simultaneously will likely require system optimization or prioritization based on system economics. Ultimately, this work successfully demonstrates FMEA as a risk analysis approach for other bioenergy process systems. Full article
(This article belongs to the Special Issue Thermochemical Conversions of Biomass and Its Safety Evaluation)
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18 pages, 7828 KiB  
Article
A Few-Shot Object Detection Method for Endangered Species
by Hongmei Yan, Xiaoman Ruan, Daixian Zhu, Haoran Kong and Peixuan Liu
Appl. Sci. 2024, 14(11), 4443; https://doi.org/10.3390/app14114443 (registering DOI) - 23 May 2024
Abstract
Endangered species detection plays an important role in biodiversity conservation and is significant in maintaining ecological balance. Existing deep learning-based object detection methods are overly dependent on a large number of supervised samples, and building such endangered species datasets is usually costly. Aiming [...] Read more.
Endangered species detection plays an important role in biodiversity conservation and is significant in maintaining ecological balance. Existing deep learning-based object detection methods are overly dependent on a large number of supervised samples, and building such endangered species datasets is usually costly. Aiming at the problems faced by endangered species detection, such as low accuracy and easy loss of location information, an efficient endangered species detection method with fewer samples is proposed to extend the few-shot object detection technique to the field of endangered species detection, which requires only a small number of training samples to obtain excellent detection results. First, SE-Res2Net is proposed to optimize the feature extraction capability. Secondly, an RPN network with multiple attention mechanism is proposed. Finally, for the classification confusion problem, a weighted prototype-based comparison branch is introduced to construct weighted category prototype vectors, which effectively improves the performance of the original classifier. Under the setting of 30 samples in the endangered species dataset, the average detection accuracy value of the method, mAP50, reaches 76.54%, which is 7.98% higher than that of the pre-improved FSCE method. This paper also compares the algorithm on the PASCOL VOC dataset, which is optimal and has good generalization ability compared to the other five algorithms. Full article
(This article belongs to the Topic Artificial Intelligence Models, Tools and Applications)
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18 pages, 526 KiB  
Review
Telerehabilitation by Videoconferencing for Balance and Gait in People with Parkinson’s Disease: A Scoping Review
by Carla Silva-Batista, Filipe Oliveira de Almeida, Jennifer L. Wilhelm, Fay B. Horak, Martina Mancini and Laurie A. King
Geriatrics 2024, 9(3), 66; https://doi.org/10.3390/geriatrics9030066 (registering DOI) - 23 May 2024
Abstract
Although supervised and real-time telerehabilitation by videoconferencing is now becoming common for people with Parkinson’s disease (PD), its efficacy for balance and gait is still unclear. This paper uses a scoping approach to review the current evidence on the effects of telerehabilitation by [...] Read more.
Although supervised and real-time telerehabilitation by videoconferencing is now becoming common for people with Parkinson’s disease (PD), its efficacy for balance and gait is still unclear. This paper uses a scoping approach to review the current evidence on the effects of telerehabilitation by videoconferencing on balance and gait for patients with PD. We also explored whether studies have used wearable technology during telerehabilitation to assess and treat balance and gait via videoconferencing. Literature searches were conducted using PubMed, ISI’s Web of Knowledge, Cochrane’s Library, and Embase. The data were extracted for study design, treatment, and outcomes. Fourteen studies were included in this review. Of these, seven studies investigated the effects of telerehabilitation (e.g., tele-yoga and adapted physiotherapy exercises) on balance and gait measures (e.g., self-reported balance, balance scale, walking speed, mobility, and motor symptoms) using videoconferencing in both assessment and treatment. The telerehabilitation programs by videoconferencing were feasible and safe for people with PD; however, the efficacy still needs to be determined, as only four studies had a parallel group. In addition, no study used wearable technology. Robust evidence of the effects of telerehabilitation by videoconferencing on balance and gait for patients with PD was not found, suggesting that future powered, prospective, and robust clinical trials are needed. Full article
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20 pages, 3280 KiB  
Article
Comprehensive Study on the Properties of AZ91/x-Si3N4 Composites for Their Prospective Application
by Md Tanwir Alam, Tarique Ahmad, Abdulnaser M. Alshoaibi, Abdul Aziz, Dilawar Husain and Shameem Ahmad
Appl. Sci. 2024, 14(11), 4444; https://doi.org/10.3390/app14114444 (registering DOI) - 23 May 2024
Abstract
Metal alloy matrix composites are generally lightweight structural materials with a high strength-to-weight ratio. They can be extensively used in various fields of modern engineering applications, such as aerospace and automotive components and biomedical engineering. This study focuses on the development and characterization [...] Read more.
Metal alloy matrix composites are generally lightweight structural materials with a high strength-to-weight ratio. They can be extensively used in various fields of modern engineering applications, such as aerospace and automotive components and biomedical engineering. This study focuses on the development and characterization of lightweight metal alloy matrix composites for industrial applications, with a particular emphasis on magnesium (Mg) alloys as a replacement for aluminum-based alloys. Mg alloys offer significant weight advantages, being 33% lighter than aluminum and 75% lighter than steel, making them highly desirable for use in various engineering fields. In the present study, Mg (AZ91) alloy reinforced with x-Si3N4 composites (x = 0, 1, 3, 5, 7, 9 wt.%) were fabricated using a liquid state process. The AZ91/x-Si3N4 composites were evaluated through physical, mechanical, wear, and microstructural characterization. The experimental results, supported by statistical analysis, demonstrated that the incorporation of Si3N4 particles amplified the mechanical properties, wear resistance, and porosity of the composites. However, the presence of the reinforced particles resulted in reduced forgeability and elongation, limiting certain deformation characteristics. The existence of the reinforced particles within the composites was confirmed through SEM analysis, providing visual evidence of their distribution and interaction within the Mg alloy matrix. Finally, it was concluded that the implication of the study could be sought for the light structural parts of aerospace, automotive, biomedical, and prosthetic applications. Full article
(This article belongs to the Special Issue Mechanical Properties and Fatigue Behavior of Composite Materials)
13 pages, 1777 KiB  
Article
Leaf Fermentation Products of Allium sativum L. Can Alleviate Apple Replant Disease (ARD)
by Chengwen Yin, Rong Zhang, Yiming Zhao, Gongshuai Wang, Chengmiao Yin, Yusong Liu and Zhiquan Mao
Horticulturae 2024, 10(6), 546; https://doi.org/10.3390/horticulturae10060546 (registering DOI) - 23 May 2024
Abstract
Apple replant disease (ARD) is a serious threat to newly replanted apple seedlings. The alleviation of ARD is of great significance for the healthy development of the apple industry. In this study, we investigated the effects of leaf fermentation products (LFP) of Allium [...] Read more.
Apple replant disease (ARD) is a serious threat to newly replanted apple seedlings. The alleviation of ARD is of great significance for the healthy development of the apple industry. In this study, we investigated the effects of leaf fermentation products (LFP) of Allium sativum L. on the replanted soil environment and Malus hupehensis Rehd. seedlings. The results showed that LFP increased biomass accumulation, changed root architecture, increased root anti-oxidant enzyme activity, and decreased root MDA content under replanted conditions. In addition, the application of LFP increased soil nutrients and soil enzyme activity and reduced phenolic acid content. Furthermore, the LFP enriched the number of beneficial bacteria and reduced the number of harmful fungi, which positively affected the soil microbial community structure. Overall, our results demonstrated that LFP of A. sativum L. could alleviate the occurrence of ARD and provide new insights for the reuse of the leaves of A. sativum L. and the prevention of ARD. Full article
(This article belongs to the Section Protected Culture)
10 pages, 627 KiB  
Article
Antimicrobial Peptide Reduces Cytotoxicity and Inflammation in Canine Epidermal Keratinocyte Progenitor Cells Induced by Pseudomonas aeruginosa Infection
by Jae-Eun Hyun and Cheol-Yong Hwang
Vet. Sci. 2024, 11(6), 235; https://doi.org/10.3390/vetsci11060235 (registering DOI) - 23 May 2024
Abstract
The direct effects and antimicrobial activity of synthetic antimicrobial peptides (AMPs) obtained from dogs, including cBD, cBD103, and cCath, against P. aeruginosa wild-type strain PAO1 and canine keratinocytes were analyzed. Antibacterial effects on planktonic bacteria were assessed by determining the minimum bactericidal concentrations [...] Read more.
The direct effects and antimicrobial activity of synthetic antimicrobial peptides (AMPs) obtained from dogs, including cBD, cBD103, and cCath, against P. aeruginosa wild-type strain PAO1 and canine keratinocytes were analyzed. Antibacterial effects on planktonic bacteria were assessed by determining the minimum bactericidal concentrations (MBCs) of AMPs and by a time-kill assay. Antibiofilm effects were assessed using the microtiter plate assay. We also evaluated the effects of AMPs on cell cytotoxicity and host immune response induced by stimulating canine epidermal keratinocyte progenitor (CPEK) cells with PAO1 and its LPS. cBD, cBD103, and cCath all exhibited dose-dependent antimicrobial and antibiofilm effects. In particular, 25 μg/mL cBD103 showed rapid bactericidal activity within 60 min and inhibited biofilm formation. In addition, pretreatment with cBD103 (25 µg/mL) and cCath (50 µg/mL) 1 h before stimulation significantly reduced the cytotoxicity of the CPEK cells by PAO1 and LPS-induced IL-6 and TNF-a expressions. cBD had little effect on the response to PAO1 and LPS in the cells. These results indicate the therapeutic potential of AMPs in P. aeruginosa skin infections. However, further studies on the mechanism of action of AMPs in keratinocytes and clinical trials are needed. Full article
(This article belongs to the Special Issue Antimicrobial Use in Companion Animals)
15 pages, 661 KiB  
Article
Video Summarization Generation Network Based on Dynamic Graph Contrastive Learning and Feature Fusion
by Jing Zhang, Guangli Wu, Xinlong Bi and Yulong Cui
Electronics 2024, 13(11), 2039; https://doi.org/10.3390/electronics13112039 (registering DOI) - 23 May 2024
Abstract
Video summarization aims to analyze the structure and content of videos and extract key segments to construct summarization that can accurately summarize the main content, allowing users to quickly access the core information without browsing the full video. However, existing methods have difficulties [...] Read more.
Video summarization aims to analyze the structure and content of videos and extract key segments to construct summarization that can accurately summarize the main content, allowing users to quickly access the core information without browsing the full video. However, existing methods have difficulties in capturing long-term dependencies when dealing with long videos. On the other hand, there is a large amount of noise in graph structures, which may lead to the influence of redundant information and is not conducive to the effective learning of video features. To solve the above problems, we propose a video summarization generation network based on dynamic graph contrastive learning and feature fusion, which mainly consists of three modules: feature extraction, video encoder, and feature fusion. Firstly, we compute the shot features and construct a dynamic graph by using the shot features as nodes of the graph and the similarity between the shot features as the weights of the edges. In the video encoder, we extract the temporal and structural features in the video using stacked L-G Blocks, where the L-G Block consists of a bidirectional long short-term memory network and a graph convolutional network. Then, the shallow-level features are obtained after processing by L-G Blocks. In order to remove the redundant information in the graph, graph contrastive learning is used to obtain the optimized deep-level features. Finally, to fully exploit the feature information of the video, a feature fusion gate using the gating mechanism is designed to fully fuse the shallow-level features with the deep-level features. Extensive experiments are conducted on two benchmark datasets, TVSum and SumMe, and the experimental results show that our proposed method outperforms most of the current state-of-the-art video summarization methods. Full article
(This article belongs to the Section Artificial Intelligence)
20 pages, 4306 KiB  
Article
PMSNet: Multiscale Partial-Discharge Signal Feature Recognition Model via a Spatial Interaction Attention Mechanism
by Yi Deng, Jiazheng Liu, Kuihu Zhu, Quan Xie and Hai Liu
Sensors 2024, 24(11), 3342; https://doi.org/10.3390/s24113342 (registering DOI) - 23 May 2024
Abstract
Partial discharge (PD) is a localized discharge phenomenon in the insulator of electrical equipment resulting from the electric field strength exceeding the local dielectric breakdown electric field. Partial-discharge signal identification is an important means of assessing the insulation status of electrical equipment and [...] Read more.
Partial discharge (PD) is a localized discharge phenomenon in the insulator of electrical equipment resulting from the electric field strength exceeding the local dielectric breakdown electric field. Partial-discharge signal identification is an important means of assessing the insulation status of electrical equipment and critical to the safe operation of electrical equipment. The identification effect of traditional methods is not ideal because the PD signal collected is subject to strong noise interference. To overcome noise interference, quickly and accurately identify PD signals, and eliminate potential safety hazards, this study proposes a PD signal identification method based on multiscale feature fusion. The method improves identification efficiency through the multiscale feature fusion and feature aggregation of phase-resolved partial-discharge (PRPD) diagrams by using PMSNet. The whole network consists of three parts: a CNN backbone composed of a multiscale feature fusion pyramid, a down-sampling feature enhancement (DSFB) module for each layer of the pyramid to acquire features from different layers, a Transformer encoder module dominated by a spatial interaction–attention mechanism to enhance subspace feature interactions, a final categorized feature recognition method for the PRPD maps and a final classification feature generation module (F-Collect). PMSNet improves recognition accuracy by 10% compared with traditional high-frequency current detection methods and current pulse detection methods. On the PRPD dataset, the validation accuracy of PMSNet is above 80%, the validation loss is about 0.3%, and the training accuracy exceeds 85%. Experimental results show that the use of PMSNet can greatly improve the recognition accuracy and robustness of PD signals and has good practicality and application prospects. Full article
(This article belongs to the Section Electronic Sensors)
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21 pages, 12155 KiB  
Article
Reprogramming Glioblastoma Cells into Non-Cancerous Neuronal Cells as a Novel Anti-Cancer Strategy
by Michael Q. Jiang, Shan Ping Yu, Takira Estaba, Emily Choi, Ken Berglund, Xiaohuan Gu and Ling Wei
Cells 2024, 13(11), 897; https://doi.org/10.3390/cells13110897 (registering DOI) - 23 May 2024
Abstract
Glioblastoma Multiforme (GBM) is an aggressive brain tumor with a high mortality rate. Direct reprogramming of glial cells to different cell lineages, such as induced neural stem cells (iNSCs) and induced neurons (iNeurons), provides genetic tools to manipulate a cell’s fate as a [...] Read more.
Glioblastoma Multiforme (GBM) is an aggressive brain tumor with a high mortality rate. Direct reprogramming of glial cells to different cell lineages, such as induced neural stem cells (iNSCs) and induced neurons (iNeurons), provides genetic tools to manipulate a cell’s fate as a potential therapy for neurological diseases. NeuroD1 (ND1) is a master transcriptional factor for neurogenesis and it promotes neuronal differentiation. In the present study, we tested the hypothesis that the expression of ND1 in GBM cells can force them to differentiate toward post-mitotic neurons and halt GBM tumor progression. In cultured human GBM cell lines, including LN229, U87, and U373 as temozolomide (TMZ)-sensitive and T98G as TMZ-resistant cells, the neuronal lineage conversion was induced by an adeno-associated virus (AAV) package carrying ND1. Twenty-one days after AAV-ND1 transduction, ND1-expressing cells displayed neuronal markers MAP2, TUJ1, and NeuN. The ND1-induced transdifferentiation was regulated by Wnt signaling and markedly enhanced under a hypoxic condition (2% O2 vs. 21% O2). ND1-expressing GBM cultures had fewer BrdU-positive proliferating cells compared to vector control cultures. Increased cell death was visualized by TUNEL staining, and reduced migrative activity was demonstrated in the wound-healing test after ND1 reprogramming in both TMZ-sensitive and -resistant GBM cells. In a striking contrast to cancer cells, converted cells expressed the anti-tumor gene p53. In an orthotopical GBM mouse model, AAV-ND1-reprogrammed U373 cells were transplanted into the fornix of the cyclosporine-immunocompromised C57BL/6 mouse brain. Compared to control GBM cell-formed tumors, cells from ND1-reprogrammed cultures formed smaller tumors and expressed neuronal markers such as TUJ1 in the brain. Thus, reprogramming using a single-factor ND1 overcame drug resistance, converting malignant cells of heterogeneous GBM cells to normal neuron-like cells in vitro and in vivo. These novel observations warrant further research using patient-derived GBM cells and patient-derived xenograft (PDX) models as a potentially effective treatment for a deadly brain cancer and likely other astrocytoma tumors. Full article
(This article belongs to the Special Issue Glioblastoma: What Do We Know?)
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13 pages, 3066 KiB  
Article
Context Privacy Preservation for User Validation by Wireless Sensors in the Industrial Metaverse Access System
by John Owoicho Odeh, Xiaolong Yang, Cosmas Ifeanyi Nwakanma and Sahraoui Dhelim
Algorithms 2024, 17(6), 225; https://doi.org/10.3390/a17060225 (registering DOI) - 23 May 2024
Abstract
The Industrial Metaverse provides unparalleled prospects for increasing productivity and efficiency across multiple sectors. As wireless sensor networks play an important role in data collection and transmission within this ecosystem, preserving context privacy becomes critical to protecting sensitive information. This paper investigates the [...] Read more.
The Industrial Metaverse provides unparalleled prospects for increasing productivity and efficiency across multiple sectors. As wireless sensor networks play an important role in data collection and transmission within this ecosystem, preserving context privacy becomes critical to protecting sensitive information. This paper investigates the issue of context privacy preservation for user validation via AccesSensor in the Industrial Metaverse and presents a technological method to address it. We explore the need for context privacy, look at existing privacy preservation solutions, and propose novel user validation methods that are customized to the Industrial Metaverse’s access system. This method is evaluated on time-based efficiency, privacy method and bandwidth utilization. Our method performs better as compared to the DPSensor. Our research seeks to provide insights and recommendations for developing strong privacy protection methods in wireless sensor networks that operate within the Industrial Metaverse ecosystem. Full article
(This article belongs to the Special Issue AI Algorithms for Positive Change in Digital Futures)
13 pages, 599 KiB  
Article
Effects of Functional Fatigue Protocol and Visual Information on Postural Control in Patients with Chronic Ankle Instability
by Kyungeon Kim, Hyunsoo Kim, Kyeongtak Song, Suji Yoon, Eun Ji Hong, Hyung Gyu Jeon, Kyoung Uk Oh and Sae Yong Lee
Appl. Sci. 2024, 14(11), 4445; https://doi.org/10.3390/app14114445 (registering DOI) - 23 May 2024
Abstract
Chronic ankle instability (CAI) patients often exhibit postural control deficits and rely on visual information to maintain static balance to compensate for decreased proprioception. Fatigue impairs neuromuscular control, in addition to postural control, in CAI patients. However, whether functional fatiguing exercises alter postural [...] Read more.
Chronic ankle instability (CAI) patients often exhibit postural control deficits and rely on visual information to maintain static balance to compensate for decreased proprioception. Fatigue impairs neuromuscular control, in addition to postural control, in CAI patients. However, whether functional fatiguing exercises alter postural control and sensory organization strategies during single-leg balance tests in CAI patients remains unclear. This study involved a controlled trial on 28 CAI patients in a laboratory setting. Each participant performed a single-leg balance test with eyes open (EO) and eyes closed (EC) before and after a functional fatigue protocol. Two-way repeated-measures ANOVA evaluated fatigue (pre- vs. post-fatigue) × vision (EO vs. EC) interactions for outcome variables. Additionally, paired-sample t-tests examined differences between two conditions (pre- vs. post-fatigue) for time-to-boundary (TTB) minima (%modulation). We found significant interactions between fatigue and vision conditions in ML and AP TTBmeans and AP TTBsds. %Modulations were significantly decreased after fatigue in AP TTBmean, ML TTBsd, and AP TTBsd. In conclusion, static postural control ability decreased after the functional fatigue protocol with EO, but was unchanged with EC. This suggests that decreased balance ability is more pronounced with EO under fatigue due to less visual dependence. This may increase ankle sprain incidence under fatigue. Full article
(This article belongs to the Special Issue Advances in Foot Biomechanics and Gait Analysis)
25 pages, 6060 KiB  
Article
A Multisubstructure-Based Method for the Assessment of Displacement and Stress in a Fluid–Structure Interaction Framework
by Changchuan Xie, Kunhui Huang, Yang Meng, Nongyue Gao and Zhitao Zhang
Aerospace 2024, 11(6), 423; https://doi.org/10.3390/aerospace11060423 (registering DOI) - 23 May 2024
Abstract
A multisubstructure-based method for assessing the deformation and stress of a fine-meshed model according to a coarse model was proposed. Integrating boundary conditions in a local fine-meshed model, a displacement mapping matrix from the coarse model to the fine-meshed model was constructed. The [...] Read more.
A multisubstructure-based method for assessing the deformation and stress of a fine-meshed model according to a coarse model was proposed. Integrating boundary conditions in a local fine-meshed model, a displacement mapping matrix from the coarse model to the fine-meshed model was constructed. The method was verified by a three-level panel in a fluid–structure interaction (FSI) framework by integrating the steady vortex lattice method (VLM). A comparison between the inner deformation distribution of the coarse model and that of the global fine-meshed model obtained from MSC.Nastran was carried out, and the results showed that the coarse model failed to demonstrate reliable strains and stresses. In contrast, the proposed method in this paper can effectively depict the inner deformation and critical stress distribution. The deformation error was lower than 8%, meeting engineering requirements. Moreover, the results of different working conditions can achieve a similar relative error of displacement for an identical position. The easy storage of the displacement mapping matrix and the convenience of the boundary information transformation among all substructure levels are prominent aspects. As a result, there is a solid foundation for addressing the time-dependent problem in spite of the simultaneity and region. Full article
(This article belongs to the Special Issue Multiscale Modelling in Aerospace Engineering)
47 pages, 4890 KiB  
Article
A Taxonomic and Phylogenetic Contribution on Inosperma Section Inosperma (Agaricales, Inocybaceae) in Europe: Calamistratum and Geraniodorum Groups
by Fernando Esteve-Raventós, Ellen Larsson, Fermín Pancorbo, Enrico Bizio, Alberto Altés, Yolanda Turégano, Gabriel Moreno and Ibai Olariaga
J. Fungi 2024, 10(6), 374; https://doi.org/10.3390/jof10060374 (registering DOI) - 23 May 2024
Abstract
The aim of this study is to carry out a taxonomic revision of the groups Calamistratum and Geraniodorum of the genus Inosperma sect. Inosperma in Europe. For this purpose, a multigenic phylogenetic analysis was carried out using the ITS, LSU, RPB1 and RPB2 [...] Read more.
The aim of this study is to carry out a taxonomic revision of the groups Calamistratum and Geraniodorum of the genus Inosperma sect. Inosperma in Europe. For this purpose, a multigenic phylogenetic analysis was carried out using the ITS, LSU, RPB1 and RPB2 markers, covering a total of 111 sequences, including those generated from the existing type-material collections. This analysis led to the recognition of nine clades or terminal groups for the European continent, correlating with nine morphological species. Three of them, I. calamistratum, I. neohirsutum sp. nov. and I. turietoense sp. nov., are distributed in humid and temperate forests, whereas I. geminum sp. nov., I. geraniodorum, I. gracilentum sp. nov., I. praetermissum comb. nov., I. subhirsutum and I. veliferum seem to be restricted to the colder altimontane, boreal and alpine climates. It is concluded that the study of morphological and ecological characteristics allows the recognition of species without the need for an often-subjective interpretation of organoleptic characteristics. Inocybe hirsuta is considered a synonym of Inosperma calamistratum, Inosperma praetermissum as a different species from I. calamistratum, and Inocybe geraniodora var. gracilenta f. salicis-herbaceae as a synonym of I. praetermissum. Four new species and one new combination are proposed. A key for the recognition of the European species is provided. Illustrations and photographs of macro- and micromorphological characters and SEM spores of all species are presented. Full article
(This article belongs to the Special Issue Taxonomy, Systematics and Evolution of Forestry Fungi, 2nd Edition)
32 pages, 1972 KiB  
Review
Induced Partial Saturation: From Mechanical Principles to Engineering Design of an Innovative and Eco-Friendly Countermeasure against Earthquake-Induced Soil Liquefaction
by Lucia Mele, Stefania Lirer and Alessandro Flora
Geosciences 2024, 14(6), 140; https://doi.org/10.3390/geosciences14060140 (registering DOI) - 23 May 2024
Abstract
Earthquake-induced soil liquefaction is a catastrophic phenomenon that can damage existing building foundations and other structures, resulting in significant economic losses. Traditional mitigation techniques against liquefaction present critical aspects, such as high construction costs, impact on surrounding infrastructure and effects on the surrounding [...] Read more.
Earthquake-induced soil liquefaction is a catastrophic phenomenon that can damage existing building foundations and other structures, resulting in significant economic losses. Traditional mitigation techniques against liquefaction present critical aspects, such as high construction costs, impact on surrounding infrastructure and effects on the surrounding environment. Therefore, research is ongoing in order to develop new approaches and technologies suitable to mitigate liquefaction risk. Among the innovative countermeasures against liquefaction, Induced Partial Saturation (IPS) is considered one of the most promising technologies. It consists of introducing gas/air bubbles into the pore water of sandy soils in order to increase the compressibility of the fluid phase and then enhance liquefaction resistance. IPS is economical, eco-friendly and suitable for urbanised areas, where the need to reduce the risk of liquefaction must be addressed, taking into account the integrity of existing buildings. However, IPS is still far from being a routine technology since more aspects should be better understood. The main aim of this review is to raise some important questions and encourage further research and discussions on this topic. The review first analyses and discusses the effects of air/gas bubbles on the cyclic behaviour of sandy soils, focusing on the soil volume element scale and then extending the considerations to the real scale. The use of useful design charts is also described. Moreover, a section will be devoted to the effect of IPS under shallow foundations. The readers will fully understand the research trend of IPS liquefaction mitigation and will be encouraged to further explore new practical aspects to overcome the application difficulties and contribute to spreading the use of this technology. Full article
(This article belongs to the Special Issue Earthquake-Induced Soil Liquefaction: From Small to Large Scale)
19 pages, 2293 KiB  
Article
In Vitro and In Silico Anti-Glioblastoma Activity of Hydroalcoholic Extracts of Artemisia annua L. and Artemisia vulgaris L.
by Jurga Bernatoniene, Emilija Nemickaite, Daiva Majiene, Mindaugas Marksa and Dalia M. Kopustinskiene
Molecules 2024, 29(11), 2460; https://doi.org/10.3390/molecules29112460 (registering DOI) - 23 May 2024
Abstract
Glioblastoma, the most aggressive and challenging brain tumor, is a key focus in neuro-oncology due to its rapid growth and poor prognosis. The C6 glioma cell line is often used as a glioblastoma model due to its close simulation of human glioma characteristics, [...] Read more.
Glioblastoma, the most aggressive and challenging brain tumor, is a key focus in neuro-oncology due to its rapid growth and poor prognosis. The C6 glioma cell line is often used as a glioblastoma model due to its close simulation of human glioma characteristics, including rapid expansion and invasiveness. Alongside, herbal medicine, particularly Artemisia spp., is gaining attention for its anticancer potential, offering mechanisms like apoptosis induction, cell cycle arrest, and the inhibition of angiogenesis. In this study, we optimized extraction conditions of polyphenols from Artemisia annua L. and Artemisia vulgaris L. herbs and investigated their anticancer effects in silico and in vitro. Molecular docking of the main phenolic compounds of A. annua and A. vulgaris and potential target proteins, including programmed cell death (apoptosis) pathway proteins proapoptotic Bax (PDB ID 6EB6), anti-apoptotic Bcl-2 (PDB ID G5M), and the necroptosis pathway protein (PDB ID 7MON), mixed lineage kinase domain-like protein (MLKL), in complex with receptor-interacting serine/threonine-protein kinase 3 (RIPK3), revealed the high probability of their interactions, highlighting the possible influence of chlorogenic acid in modulating necroptosis processes. The cell viability of rat C6 glioma cell line was assessed using a nuclear fluorescent double-staining assay with Hoechst 33342 and propidium iodide. The extracts from A. annua and A. vulgaris have demonstrated anticancer activity in the glioblastoma model, with the synergistic effects of their combined compounds surpassing the efficacy of any single compound. Our results suggest the potential of these extracts as a basis for developing more effective glioblastoma treatments, emphasizing the importance of further research into their mechanisms of action and therapeutic applications. Full article
16 pages, 4092 KiB  
Article
Dynamic Analysis and Sliding Mode Synchronization Control of Chaotic Systems with Conditional Symmetric Fractional-Order Memristors
by Huaigu Tian, Mingwei Zhao, Jindong Liu, Qiao Wang, Xiong Yu and Zhen Wang
Fractal Fract. 2024, 8(6), 307; https://doi.org/10.3390/fractalfract8060307 (registering DOI) - 23 May 2024
Abstract
In this paper, the characteristics of absolute value memristors are verified through the circuit implementation and construction of a chaotic system with a conditional symmetric fractional-order memristor. The dynamic behavior of fractional-order memristor systems is explored using fractional-order calculus theory and the Adomian [...] Read more.
In this paper, the characteristics of absolute value memristors are verified through the circuit implementation and construction of a chaotic system with a conditional symmetric fractional-order memristor. The dynamic behavior of fractional-order memristor systems is explored using fractional-order calculus theory and the Adomian Decomposition Method (ADM). Concurrently, the investigation probes into the existence of coexisting symmetric attractors, multiple coexisting bifurcation diagrams, and Lyapunov exponent spectra (LEs) utilizing system parameters as variables. Additionally, the system demonstrates an intriguing phenomenon known as offset boosting, where the embedding of an offset can adjust the position and size of the system’s attractors. To ensure the practical applicability of these findings, a fractional-order sliding mode synchronization control scheme, inspired by integer-order sliding mode theory, is designed. The rationality and feasibility of this scheme are validated through a theoretical analysis and numerical simulation. Full article
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13 pages, 594 KiB  
Article
Molecular Markers and Antimicrobial Resistance Patterns of Extraintestinal Pathogenic Escherichia coli from Camel Calves Including Colistin-Resistant and Hypermucoviscuous Strains
by Domonkos Sváb, Zoltán Somogyi, István Tóth, Joseph Marina, V. Jose Shantymol, John Jeeba, Anas Safna, Judit Juhász, Péter Nagy, Ahmed Mohamed Taha Abdelnassir, Ahmed Abdelrhman Ismail and László Makrai
Trop. Med. Infect. Dis. 2024, 9(6), 123; https://doi.org/10.3390/tropicalmed9060123 (registering DOI) - 23 May 2024
Abstract
Extraintestinal pathogenic Escherichia coli (ExPEC) strains are capable of causing various systemic infections in both humans and animals. In this study, we isolated and characterized 30 E. coli strains from the parenchymatic organs and brains of young (<3 months of age) camel calves [...] Read more.
Extraintestinal pathogenic Escherichia coli (ExPEC) strains are capable of causing various systemic infections in both humans and animals. In this study, we isolated and characterized 30 E. coli strains from the parenchymatic organs and brains of young (<3 months of age) camel calves which died in septicemia. Six of the strains showed hypermucoviscous phenotype. Based on minimum inhibitory concentration (MIC) values, seven of the strains were potentially multidrug resistant, with two additional showing colistin resistance. Four strains showed mixed pathotypes, as they carried characteristic virulence genes for intestinal pathotypes of E. coli: three strains carried cnf1, encoding cytotoxic necrotizing factor type 1, the key virulence gene of necrotoxigenic E. coli (NTEC), and one carried eae encoding intimin, the key virulence gene of enteropathogenic E. coli (EPEC). An investigation of the integration sites of pathogenicity islands (PAIs) and the presence of prophage-related sequences showed that the strains carry diverse arrays of mobile genetic elements, which may contribute to their antimicrobial resistance and virulence patterns. Our work is the first to describe ExPEC strains from camels, and points to their veterinary pathogenic as well as zoonotic potential in this important domestic animal. Full article
(This article belongs to the Special Issue Foodborne Zoonotic Bacterial Infections)
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12 pages, 22239 KiB  
Article
Microstructure Evolution of Polyacrylonitrile-Based Fibers during Thermal Pre-Oxidation
by Yue Sun, Yanxiang Wang, Lanzhong Wang, Yongbo Wang, Bohan Ding, Jinghe Guo, Shichao Dai and Yuxia Wang
J. Compos. Sci. 2024, 8(6), 198; https://doi.org/10.3390/jcs8060198 (registering DOI) - 23 May 2024
Abstract
In this work, pre-oxidized polyacrylonitrile fibers are treated with ultrasonic etching and solution etching to produce ultra-thin sections. The evolution of the fibers’ microstructure in the pre-oxidation process is observed, and the transformation model of the microstructure of the pre-oxidized fibers is proposed. [...] Read more.
In this work, pre-oxidized polyacrylonitrile fibers are treated with ultrasonic etching and solution etching to produce ultra-thin sections. The evolution of the fibers’ microstructure in the pre-oxidation process is observed, and the transformation model of the microstructure of the pre-oxidized fibers is proposed. Scanning electron microscopy and high-resolution transmission electron microscopy were used to observe the microstructure changes of the fibers. Fourier transform infrared spectroscopy and X-ray diffraction were used to observe the chemical structure transformation and crystallization degree of the fibers in the pre-oxidation process. The results revealed that pre-oxidized fibers exhibited a smooth surface, while their interior consisted of fibrils. The longitudinal microfibrils were connected by the transverse microfibrils and amorphous regions. The fracture morphology of the fibers shifted from ductile to brittle, and the cross-section gradually became smoother. The linear molecular chain of PAN transformed into a ring structure as pre-oxidation progressed, subsequently leading to the cross-linking of this ring structure into an orderly trapezoidal configuration. The connection between the fibrils was enhanced, and the fiber structure became more compact and stable. Full article
(This article belongs to the Special Issue Polymer Composites and Fibers, Volume II)
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15 pages, 1857 KiB  
Article
Accumulation of Particles in an Annular Centrifugal Contactor Cascade and the Effect upon the Extraction of Nitric Acid
by Alastair Baker, Alex Fells, Natalia Domenech-Garcia, Chris J. Maher and Bruce C. Hanson
Separations 2024, 11(6), 163; https://doi.org/10.3390/separations11060163 (registering DOI) - 23 May 2024
Abstract
Centrifugal contactors (CCs) are a technology candidate for the development of advanced reprocessing flowsheets. While they offer many advantages, such as process intensification, there are still uncertainties regarding their industrial deployment. The presence of particles in the process streams in particular may present [...] Read more.
Centrifugal contactors (CCs) are a technology candidate for the development of advanced reprocessing flowsheets. While they offer many advantages, such as process intensification, there are still uncertainties regarding their industrial deployment. The presence of particles in the process streams in particular may present a challenge to both performance and operability. Preliminary studies have been undertaken to evaluate the accumulation of particles in the contactors and the effect upon the extraction behaviour of nitric acid. Aluminium oxide (Al2O3) particles were suspended in the aqueous feed solution during the operation of a three-stage, 40 mm diameter CC cascade. The presence of insoluble solid particles in the aqueous feed, up to 7 g/L, were not observed to affect phase separation and entrainment under the experimental conditions investigated. The particles were centrifuged out of solution and accumulated as a thin cake/bed in the rotors of each stage. This work also illustrates that particles do entrain through the cascade. The predominant effect on the rate of accumulation was particle concentration in the aqueous feed solution, and increasing solids loading was observed to have an impact upon the extraction of nitric acid across the cascade. Full article
(This article belongs to the Section Separation Engineering)
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17 pages, 1379 KiB  
Article
Experimental Investigation and Theoretical Analysis of Flame Spread Dynamics over Discrete Thermally Thin Fuels with Various Inclination Angles and Gap Sizes
by Xiaoliang Zhang, Shibing Kuang, Yanli Zhao, Jun Zhang and Shengfeng Luo
Fire 2024, 7(6), 177; https://doi.org/10.3390/fire7060177 (registering DOI) - 23 May 2024
Abstract
Flame spread over discrete fuels is a typical phenomenon in fire scenes. Experimental and theoretical research on flame spread over discrete thermally thin fuels separated by air gaps with different inclination angles was conducted in the present study. Experiments with six inclination angles [...] Read more.
Flame spread over discrete fuels is a typical phenomenon in fire scenes. Experimental and theoretical research on flame spread over discrete thermally thin fuels separated by air gaps with different inclination angles was conducted in the present study. Experiments with six inclination angles ranging from 0° to 85° and various fuel coverage rates from 0.421 to 1 were designed. The flame spread behavior, the characteristic flame size, and the flame spread rate were analyzed. The results show that the flow pattern, stability, and flame size exhibit different characteristics with different inclination angles and gap sizes. As the inclination angle increases, particularly with smaller gaps, turbulent and oscillating flames are observed, while larger gap sizes promote flame stability. The mechanism of flame propagation across the gap depends on the interplay between the flame jump effect and heat transfer, which evolves with gap size. Average flame height, average flame width, and flame spread rate initially increase and then decline with the increase in fuel coverage, peaking at fuel coverage rates between 0.93 and 0.571 for different inclination angles. A theoretical model is proposed to predict the flame spread rate and the variation in the flame spread rate with inclination angle and fuel coverage. Furthermore, the map determined by inclination angle and fuel coverage is partitioned into distinct regions, comprising the accelerated flame spread region, the flame spread weakening region, and the failed flame spread region. These findings provide valuable insights into flame spread dynamics over discrete thermally thin fuels under diverse conditions. Full article
23 pages, 3014 KiB  
Article
Tool Wear Monitoring In Micro-Milling Based on Digital Twin Technology with an Extended Kalman Filter
by Christiand, Gandjar Kiswanto, Ario Sunar Baskoro, Zulhendri Hasymi and Tae Jo Ko
J. Manuf. Mater. Process. 2024, 8(3), 108; https://doi.org/10.3390/jmmp8030108 (registering DOI) - 23 May 2024
Abstract
In order to avoid catastrophic events that degrade the quality of machined products, such as tool breakage, it is vital to have a prognostic system for monitoring tool wear during the micro-milling process. Despite the long history of the tool wear monitoring field, [...] Read more.
In order to avoid catastrophic events that degrade the quality of machined products, such as tool breakage, it is vital to have a prognostic system for monitoring tool wear during the micro-milling process. Despite the long history of the tool wear monitoring field, creating such a system to track, monitor, and foresee the rapid progression of tool wear still needs to be improved in the application of micro-milling. On the other hand, digital twin technology has recently become widely recognized as significant in manufacturing and, notably, within the Industry 4.0 ecosystem. Digital twin technology is considered a potential breakthrough in developing a prognostic tool wear monitoring system, as it enables the tracking, monitoring, and prediction of the dynamics of a twinned object, e.g., a CNC machine tool. However, few works have explored the digital twin technology for tool wear monitoring, particularly in the micro-milling field. This paper presents a novel tool wear monitoring system for micro-milling machining based on digital twin technology and an extended Kalman filter framework. The proposed system provides wear progression notifications to assist the user in making decisions related to the machining process. In an evaluation using four machining datasets of slot micro-milling, the proposed system achieved a maximum error mean of 0.038 mm from the actual wear value. The proposed system brings a promising opportunity to widen the utilization of digital twin technology with the extended Kalman filter framework for seamless data integration for wear monitoring service. Full article

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