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Comparaison des modeles de neurone de Hodgkin-Huxley et de Nelson

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Abstract

Le modèle de Nelson peut-être considéré comme une approximation du modèle de Hodgkin-Huxley. Moins précis, il est plus maniable. Le modèle de Nelson peut également être considéré comme une généralisation du modèle de Hodgkin-Huxley. En effet, il introduit des liaisons synaptiques localisées ou diffusantes, et un processus de facilitation. Le mécanisme des liaisons synaptiques ne se traduit pas facilement dans le langage de Hodgkin-Huxley. Par contre, le processus de facilitation s'interprète facilement.

Nelson's model can be taken as an approximation of Hodgkin-Huxley's model. Its precision is lesser, but it is more usable. Nelson's model can also be taken as a generalization of Hodgkin-Huxley's one; for it introduces localized or diffusing synaptic connexions and a facilitating process. The mechanism of synaptic connexions cannot be easily translated into Hodgkin-Huxley's language. On the contrary, the facilitating process is easily interpreted.

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Nelson, P. Comparaison des modeles de neurone de Hodgkin-Huxley et de Nelson. Bulletin of Mathematical Biophysics 28, 347–354 (1966). https://doi.org/10.1007/BF02476815

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  • DOI: https://doi.org/10.1007/BF02476815

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