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Heat-acclerated radioinactivation of attenuated poliovirus

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Summary

Attenuated poliovirus is inactivated in a synergistic manner when exposed simultaneously to heat and ionizing radiation. The synergistic response is observed in both the thermally labile and stable forms of the virus. A three-term kinetic model may be used to describe the inactivation response of the virus in a theral and/or radiation environment

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Authors and Affiliations

  1. Department 5250, Sandia Laboratories, 87115, Albuquerque, New Mexico, USA

    V. L. Dugan &  R. E. Trujillo

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  1. V. L. Dugan
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  2. R. E. Trujillo
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Dugan, V.L., Trujillo, R.E. Heat-acclerated radioinactivation of attenuated poliovirus. Radiat Environ Biophys 12, 187–195 (1975). https://doi.org/10.1007/BF01327346

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  • DOI: https://doi.org/10.1007/BF01327346

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