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Detection of morphine and monoacetylmorphine (MAM) in human hair

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Summary

The detection of opiates and their metabolites in human hair has obtained an increasing importance in forensic toxicology, but many compounds [e.g. the heroin marker 6-monoacetylmorphine (MAM)] are regularly destroyed by the use of invasive extraction and hydrolysis procedures. This paper describes a method for the analysis of such sensible structures by means of guanidine/mercaptoethanol treatment, followed by specific solid phase extraction. The detection limit is better than 1 μg/g hair.

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References

  1. Baumgartner AM, Jones PF, Baumgartner WA, Black CT (1979) J Nucl Med 20:748–752

    Google Scholar 

  2. Sachs H, Arnold W (1989) J Clin Chem Clin Biochem 27:873–877

    Google Scholar 

  3. Fehn J, Megges G (1985) J Anal Toxicol 9:134–138

    Google Scholar 

  4. Denk R, Raff I, Sachs H (1991) Toxichem + Krimtech 58:79–83

    Google Scholar 

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Authors and Affiliations

  1. Institute for Legal Medicine, University of Giessen, Frankfurter Strasse 58, W-6300, Giessen, Federal Republic of Germany

    B. Ahrens, F. Erdmann, G. Rochholz & H. Schütz

Authors
  1. B. Ahrens
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  2. F. Erdmann
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  3. G. Rochholz
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  4. H. Schütz
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Ahrens, B., Erdmann, F., Rochholz, G. et al. Detection of morphine and monoacetylmorphine (MAM) in human hair. Fresenius J Anal Chem 344, 559–560 (1992). https://doi.org/10.1007/BF00324655

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  • DOI: https://doi.org/10.1007/BF00324655

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