Abstract
THE shrinkage temperature of the collagen of dura mater or fascia lata has been shown to increase with age1. Shrinkage of these tissues and tendon or skin can be watched and a micro-melting point apparatus was used for their determinations. The transition can also be detected from force–temperature curves, and use of this method has shown an increase of shrinkage temperature with age for tendon collagen, except when measurements were made at pH less than 4.5. If the fibres were maintained at constant length during the heating, the shrinkage temperature showed little variation with age (or pH)2–4.
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DICKSON, I., HAPPEY, F., PEARSON, C. et al. Decrease in Hydrothermal Stability of Collagen on Ageing in the Human Intervertebral Disk. Nature 215, 50–52 (1967). https://doi.org/10.1038/215050b0
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DOI: https://doi.org/10.1038/215050b0
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