Summary
Attenuated poliovirus is inactivated in a synergistic manner when exposed simultaneously to heat and ionizing radiation. The synergistic response is observed in both the thermally labile and stable forms of the virus. A three-term kinetic model may be used to describe the inactivation response of the virus in a theral and/or radiation environment
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Dugan, V.L., Trujillo, R.E. Heat-acclerated radioinactivation of attenuated poliovirus. Radiat Environ Biophys 12, 187–195 (1975). https://doi.org/10.1007/BF01327346
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DOI: https://doi.org/10.1007/BF01327346