Overview
- Editors:
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Veronica Ghini
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Department of Chemistry, University of Florence, Sesto Fiorentino, Florence, Italy
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Kathleen A. Stringer
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Department of Clinical Pharmacy, University of Michigan–Ann Arbor, Ann Arbor, USA
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Claudio Luchinat
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Department of Chemistry, University of Florence, Sesto Fiorentino, Florence, Italy
- Demonstrates how to generate metabolomics data including lipidomics/lipoproteomics
- Helps understand mechanistic underpinnings of adverse drug events
- Covers applications of metabolomics for phenotyping complex diseases
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Table of contents (13 chapters)
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Front Matter
Pages i-viii
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- David S. Wishart, Manoj Rout, Brian L. Lee, Mark Berjanskii, Marcia LeVatte, Matthias Lipfert
Pages 1-41
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- Rylan Hissong, Kendra R. Evans, Charles R. Evans
Pages 43-71
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- Hye Kyong Kim, Young Hae Choi, Robert Verpoorte
Pages 117-141
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- G. A. Nagana Gowda, Daniel Raftery
Pages 143-164
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- Martin Forbes, Sabrina Geisberger, Matthias Pietzke, Guido Mastrobuoni, Stefan Kempa
Pages 165-180
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- Zuhal Eraslan, Marta Cascante, Ulrich L. Günther
Pages 181-207
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- Alessia Vignoli, Gaia Meoni, Veronica Ghini, Francesca Di Cesare, Leonardo Tenori, Claudio Luchinat et al.
Pages 209-245
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- Rachel S. Kelly, Margaret F. Cote, Sofina Begum, Jessica Lasky-Su
Pages 247-273
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- Maider Bizkarguenaga, Rubén Gil-Redondo, Chiara Bruzzone, Ganeko Bernardo-Seisdedos, Ana Laín, Beatriz González-Valle et al.
Pages 275-297
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- Ciao-Sin Chen, Daniel L. Hertz
Pages 299-337
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- Subhabrata Moitra, Arghya Bandyopadhyay, Paige Lacy
Pages 339-365
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- Ana E. Pacheco-Navarro, Angela J. Rogers
Pages 367-384
About this book
This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su,Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.