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31P magnetic resonance spectroscopy of the liver in an infant with galactosaemia

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Abstract

Sequential studies of the liver of an infant with galactosaemia were made by phosphorus magnetic resonance spectroscopy (31P MRS). A peak attributable to galactose 1-phosphate (gal 1-P) was seen in early liver spectra. This peak diminished during dietary therapy in the early months of life, corresponding to a falling level of gal 1-P in red blood cells.

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Authors and Affiliations

  1. Department of Paediatrics, John Raddiffe Hospital, Oxford, UK

    J. P. Smyth & P. L. Hope

  2. Medical Research Council Biochemical and Clinical Magnetic Resonance Unit, John Radcliffe Hospital, Oxford, UK

    R. M. Dixon, R. Ouwerkerk, B. Rajagopalan & G. K. Radda

Authors
  1. J. P. Smyth
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  2. P. L. Hope
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  3. R. M. Dixon
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  4. R. Ouwerkerk
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  5. B. Rajagopalan
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  6. G. K. Radda
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Smyth, J.P., Hope, P.L., Dixon, R.M. et al. 31P magnetic resonance spectroscopy of the liver in an infant with galactosaemia. MAGMA 1, 119–121 (1993). https://doi.org/10.1007/BF01769412

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  • DOI: https://doi.org/10.1007/BF01769412

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