Insights into mitochondrial DNA packaging
A study by Isaac et al. presents mtFiber-seq, a method that measures individual mitochondrial genome packaging at nucleotide resolution, providing insight into the architecture of mtDNA packaging.
A study by Isaac et al. presents mtFiber-seq, a method that measures individual mitochondrial genome packaging at nucleotide resolution, providing insight into the architecture of mtDNA packaging.
Cryo-electron microscopy of brain tissue from two individuals with Down syndrome showed amyloid-β (Aβ) and tau filaments identical to those found in individuals with sporadic or dominantly inherited Alzheimer disease (AD), but also two types of Aβ40 filaments with distinct structures different from those previously reported in AD and cerebral amyloid angiopathy.